DOCSLIB.ORG

Lipids Posterpub2000.Pub

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

58th Annual Meeting of the Society of General Physiologists Organized by Don Hilgemann, Scott Emr & Pietro De Camilli September 8-12, 2004 Marine Biological Laboratory Woods Hole, Massachusetts Feature Lectures Lew Cantley - Harvard University Scott Emr - HHMI, UC - San Diego Lipid sensors, domains & energies Stuart McLaughlin - SUNY, Stony Brook Evan Evans - UBC, Vancouver Lipid Tobias Meyer - Stanford University Jim Hurley - NIDDK-NIH Michael Overduin - University of Colorado i Signaling Membrane trafficking n Pietro De Camilli - HHMI, Yale University Nils Brose - Max Planck, Göttingen Physiology Gisou van der Goot - Université de Geneve Sergio Grinstein - Hospital for Sick Children sponsored in part Toronto by a major grant from Pfizer, Inc. Cytoskeleton & motility Ion channels & transporters Mike Sheetz - Columbia University Bertil Hille - University of Washington Helen Yin - UTSW, Dallas Don Hilgemann - UTSW, Dallas Dieter Klopfenstein Diomedes Logothetis - Mount Sinai UC - San Francisco Roger Hardie - University of Cambridge Silvia Corvera UMass Worcester David Julius - UC - San Francisco Peter Devreotes HHMI, Johns Hopkins Feature Lecture Michael Brown - UTSW, Dallas New horizons in lipid-protein interactions Steve White - UC, Irvine Gunnar von Heijne - Stockholm University Roderick MacKinnon - HHMI, Rockefeller Feature Lecture Jack Dixon - University of California, San Diego A number of symposium awards are available to postdoctoral fel- Abstract deadline -April 15, 2004 lows and students to help defray costs of attending the 2004 SGP www.sgpweb.org symposium. 508-540-6719 Formal sessions begin at 7 p.m. on September 8 and end at 12:30 p.m. on September 11. The afternoon and evening of September 11 Society of General Physiologists, P.O. Box 257, Woods Hole, MA 02543 are free for continued discussions with poster presenters and T: 508-540-6719, F: 508-540-0155, E: [email protected], W: www.sgpweb.org meeting attendees as well as sight-seeing. .
Recommended publications
  • Bertil Hille

    Bertil Hille

    Bertil Hille BORN: New Haven, Connecticut October 10, 1940 EDUCATION: Yale University, B.S. (1962) The Rockefeller University, Ph.D. (1967) APPOINTMENTS: Fellow, Cambridge University, Physiological Laboratory, Cambridge, England (1967–1968) Assistant Professor, University of Washington, Department of Physiology and Biophysics (1968–1971); Associate Professor (1971–1974); Professor (1974–present) Wayne E. Crill Endowed Professor, University of Washington, Department of Physiology and Biophysics (2005–present) HONORS AND AWARDS (SELECTED): Kenneth S. Cole Award of the Biophysical Society Membrane Biophysics Subgroup (1975) Mathilde Solowey Award in Neurosciences from NIH Foundation for Advanced Education in the Sciences (1976) Member of NIH NINDS Physiology Study Section (1981–1984) National Academy of Sciences, U.S.A. (1986) Research Award from the McKnight Endowment Fund for Neuroscience (1988–1994) 3rd Annual Bristol-Myers Squibb Award for Distinguished Achievement in Neuroscience Research with Erwin Neher and Jean-Pierre Changeux (1990) Columbia University Louisa Gross Horwitz Prize for outstanding basic research in Biology or Biochemistry with Clay Armstrong (1996) 1999 Albert Lasker Award for Basic Medical Research, with Clay Armstrong and Roderick MacKinnon (1999) The 2001 Gairdner Foundation International Award with Clay Armstrong and Roderick MacKinnon (2001) Institute of Medicine (2002) Wayne E. Crill Endowed Professorship, Department of Physiology & Biophysics, University of Washington, Seattle (2005–) Doctorate of Science, honoris causa, The Rockefeller University (2008) Bertil Hille helped establish the concept of ion channels as membrane proteins forming gated aqueous pores. He showed that Na + and K+ channels of axons can be distinguished by drugs such as tetrodotoxin and tetraethylammonium ion, and that their ionic selectivity can be understood by a limiting pore size, the selectivity fi lter, and by movements of ions through a series of saturable sites.
  • Curriculum Vitae: Thomas E

    Curriculum Vitae: Thomas E

    June 12, 2018 Curriculum Vitae: Thomas E. DeCoursey {Blue = has not happened yet} Personal Married to: Carolyn Garver DeCoursey Children: Audrey G. DeCoursey, Jillian Z. DeCoursey Home: 833 S. Scoville, Oak Park, Illinois 60304-1408 Phone: (708) 524-8324 Professional Address: Department of Physiology & Biophysics Rush University Medical Center 1750 West Harrison Street Chicago, Illinois 60612-3824 Phone: (312) 942-3267 FAX (Dept.): (312) 942-8711 E-mail: [email protected] url: http://www2.phys.rush.edu/TomD/physiotd.html ORCID iD: 0000-0002-4263-180X Alter ego: Captain Proton Education Manchester College, Indiana 1969-1971 Georg-August-Universität Göttingen, W. Germany 1971-1972 McPherson College, Kansas (B.A.) 1972-1974 Biology. Valedictorian, summa cum laude University of Cincinnati, Ohio (Ph.D.) 1974-1979 Pharmacology and Cell Biophysics Sodium currents in normal and myotonic muscle fibers. 1979. Advisor: Shirley H. Bryant Postdoctoral Training 1980-1981 Otto F. Hutter, Institute of Physiology, University of Glasgow, Glasgow, Scotland, U.K. 1982-1985 Michael D. Cahalan, Department of Physiology & Biophysics, University of California, Irvine, California Positions 1985-1990. Assistant Professor, Department of Physiology, Rush Presbyterian St. Luke's Medical Center, Chicago, Illinois 1987-present. Co-director, Patch Clamp Center, Rush University Medical Center, Chicago, Illinois 1990-1998. Associate Professor, Department of Physiology/Molecular Biophysics and Physiology, Rush Presbyterian St. Luke's Medical Center, Chicago, Illinois 1998-2016. Professor, Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, Illinois 2017-present. Professor, Department of Physiology & Biophysics, Rush University, Chicago, Illinois 1 June 12, 2018 Honors, Fellowships, etc. Valedictorian, summa cum laude, McPherson College (1974) Fellow of the Albert J.
  • Kinetic and Pharmacological Properties of the Sodium Channel of Frog Skeletal Muscle

    Kinetic and Pharmacological Properties of the Sodium Channel of Frog Skeletal Muscle

    Kinetic and Pharmacological Properties of the Sodium Channel of Frog Skeletal Muscle DONALD T. CAMPBELL and BERTIL HILLE From the Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, Washington 98195. Dr. Campbell's present address is the Department of Physiology, Yale University School of Medicine, New Haven, Connecticut 06510. A B S T R A C T Na channels of frog skeletal muscle are studied under voltage clamp and their properties compared with those of frog myelinated nerve. A standard mathematical model is fitted to the sodium currents measured in nerve and in muscle to obtain a quantitative description of the gating kinetics. At 5°C the kinetics in frog nerve and skeletal muscle are similar except that activation proceeds five times faster in nerve. Block of Na channels by saxitoxin is measured in nerve and in muscle. The apparent dissociation constants for the inhibitory complex are about 1 nM and not significantly different in nerve and muscle. Block of Na channels by external protons in muscle is found to have an apparent pKa of 5.33 and a voltage dependence corresponding to action of 27% of the membrane potential drop. Both values are like those for nerve. Shift of the peak sodium permeability-membrane potential curve with changes of external pH and Ca ++ are found to be the same in nerve and muscle. It is concluded that Na channels of nerve and muscle are nearly the same. INTRODUCTION This paper examines properties of the Na channel of frog muscle membranes under voltage clamp conditions. The guiding question to ask is if the Na channel of muscle is similar to that of nerves taken from the same species.
  • Curriculum Vitae

    Curriculum Vitae

    Curriculum Vitae MICHAEL DANIEL CAHALAN, Ph.D. Department of Physiology & Biophysics Office Phone: (949) 824-7776 University of California Lab Phone: (949) 824-7776 Irvine, California 92697-4561 e-mail: [email protected] Lab: 285 Irvine Hall URL: http://crt.biomol.uci.edu/ EDUCATION Oberlin College: B.A. in Biology, 1970, Honors Research with Dr. Richard Levin University of Washington: Ph.D., 1974, Department of Physiology and Biophysics Laboratory of Dr. Bertil Hille Postdoctoral Training: University of Rochester, 1975. Department of Physiology, University of Pennsylvania, 1976-77. Marine Biological Lab, Woods Hole, MA Laboratory of Dr. Clay M. Armstrong FACULTY POSITIONS University of California, Irvine, California, Dept. of Physiology and Biophysics Assistant Professor, 1977 Associate Professor, 1983 Professor, 1985 Chair 1991-1995, 2007-present Distinguished Professor, 2010-present HONORS Phi Beta Kappa (junior year), 1969 Graduated Magna Cum Laude, 1970 Muscular Dystrophy Postdoc Award, 1976 NIH Research Career Development Award, 1982 Alexander von Humboldt Prize, Senior Scientist Award, Max Planck Institute for Biophysical Chemistry, Göttingen, West Germany, 1990 Athalie Clark Research Achievement Award, UCI, 1997 Kenneth S. Cole Award for Membrane Biophysics, Biophysical Society, 2000 Javits Neuroscience Investigator Award, NINDS, 2006-13 Henry Kunkel Society, elected 2008 Excellence in Teaching Award from medical students, 2009, 2011, 2013 U.S. National Academy of Sciences, elected 2010 UCI Distinguished Faculty Award for Research,
  • 2019 Historical Information

    2019 Historical Information

    2019 HISTORICAL INFORMATION Table of Contents 5515 Security Lane, Suite 1110 Rockville, Maryland 20852 Founding of the Society .......................................... ii Phone: 240-290-5600 Fax: 240-290-5555 Officers & Council ............................................... ii [email protected] Biophysical Journal .............................................. ii www.biophysics.org The Biophysicist ................................................ ii Committees ................................................... ii Subgroups ................................................... iii Future Meetings ............................................... iii Past Officers .................................................. iv Past Executive Board Members .................................... iv Past Council Members .......................................... v Past Biophysical Journal Editors & Editorial Board Members .............. vii Past Annual Meetings ........................................... xii Past BPS Lecturers .............................................. xiii Past Symposia Chairs & Topics ................................... xiii Past Award Winners .......................................... xxi Constitution & Bylaws ......................................... xxviii This document is provided by the Biophysical Society for the personal use of the members of the Society. Any commer- cial use is forbidden without written autho- rization from an officer of the Society. The use of photocopies of these pages or por- tions thereof as mailing