Important Zoonotic Diseases: Prevention and Control
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Generic Amplification and Next Generation Sequencing Reveal
Dinçer et al. Parasites & Vectors (2017) 10:335 DOI 10.1186/s13071-017-2279-1 RESEARCH Open Access Generic amplification and next generation sequencing reveal Crimean-Congo hemorrhagic fever virus AP92-like strain and distinct tick phleboviruses in Anatolia, Turkey Ender Dinçer1†, Annika Brinkmann2†, Olcay Hekimoğlu3, Sabri Hacıoğlu4, Katalin Földes4, Zeynep Karapınar5, Pelin Fatoş Polat6, Bekir Oğuz5, Özlem Orunç Kılınç7, Peter Hagedorn2, Nurdan Özer3, Aykut Özkul4, Andreas Nitsche2 and Koray Ergünay2,8* Abstract Background: Ticks are involved with the transmission of several viruses with significant health impact. As incidences of tick-borne viral infections are rising, several novel and divergent tick- associated viruses have recently been documented to exist and circulate worldwide. This study was performed as a cross-sectional screening for all major tick-borne viruses in several regions in Turkey. Next generation sequencing (NGS) was employed for virus genome characterization. Ticks were collected at 43 locations in 14 provinces across the Aegean, Thrace, Mediterranean, Black Sea, central, southern and eastern regions of Anatolia during 2014–2016. Following morphological identification, ticks were pooled and analysed via generic nucleic acid amplification of the viruses belonging to the genera Flavivirus, Nairovirus and Phlebovirus of the families Flaviviridae and Bunyaviridae, followed by sequencing and NGS in selected specimens. Results: A total of 814 specimens, comprising 13 tick species, were collected and evaluated in 187 pools. Nairovirus and phlebovirus assays were positive in 6 (3.2%) and 48 (25.6%) pools. All nairovirus sequences were closely-related to the Crimean-Congo hemorrhagic fever virus (CCHFV) strain AP92 and formed a phylogenetically distinct cluster among related strains. -
2020 Taxonomic Update for Phylum Negarnaviricota (Riboviria: Orthornavirae), Including the Large Orders Bunyavirales and Mononegavirales
Archives of Virology https://doi.org/10.1007/s00705-020-04731-2 VIROLOGY DIVISION NEWS 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales Jens H. Kuhn1 · Scott Adkins2 · Daniela Alioto3 · Sergey V. Alkhovsky4 · Gaya K. Amarasinghe5 · Simon J. Anthony6,7 · Tatjana Avšič‑Županc8 · María A. Ayllón9,10 · Justin Bahl11 · Anne Balkema‑Buschmann12 · Matthew J. Ballinger13 · Tomáš Bartonička14 · Christopher Basler15 · Sina Bavari16 · Martin Beer17 · Dennis A. Bente18 · Éric Bergeron19 · Brian H. Bird20 · Carol Blair21 · Kim R. Blasdell22 · Steven B. Bradfute23 · Rachel Breyta24 · Thomas Briese25 · Paul A. Brown26 · Ursula J. Buchholz27 · Michael J. Buchmeier28 · Alexander Bukreyev18,29 · Felicity Burt30 · Nihal Buzkan31 · Charles H. Calisher32 · Mengji Cao33,34 · Inmaculada Casas35 · John Chamberlain36 · Kartik Chandran37 · Rémi N. Charrel38 · Biao Chen39 · Michela Chiumenti40 · Il‑Ryong Choi41 · J. Christopher S. Clegg42 · Ian Crozier43 · John V. da Graça44 · Elena Dal Bó45 · Alberto M. R. Dávila46 · Juan Carlos de la Torre47 · Xavier de Lamballerie38 · Rik L. de Swart48 · Patrick L. Di Bello49 · Nicholas Di Paola50 · Francesco Di Serio40 · Ralf G. Dietzgen51 · Michele Digiaro52 · Valerian V. Dolja53 · Olga Dolnik54 · Michael A. Drebot55 · Jan Felix Drexler56 · Ralf Dürrwald57 · Lucie Dufkova58 · William G. Dundon59 · W. Paul Duprex60 · John M. Dye50 · Andrew J. Easton61 · Hideki Ebihara62 · Toufc Elbeaino63 · Koray Ergünay64 · Jorlan Fernandes195 · Anthony R. Fooks65 · Pierre B. H. Formenty66 · Leonie F. Forth17 · Ron A. M. Fouchier48 · Juliana Freitas‑Astúa67 · Selma Gago‑Zachert68,69 · George Fú Gāo70 · María Laura García71 · Adolfo García‑Sastre72 · Aura R. Garrison50 · Aiah Gbakima73 · Tracey Goldstein74 · Jean‑Paul J. Gonzalez75,76 · Anthony Grifths77 · Martin H. Groschup12 · Stephan Günther78 · Alexandro Guterres195 · Roy A. -
An Investigation on First Outbreak of Kyasanur Forest Disease In
Journal of Entomology and Zoology Studies 2015; 3(6): 239-240 E-ISSN: 2320-7078 P-ISSN: 2349-6800 An investigation on first outbreak of Kyasanur JEZS 2015; 3(6): 239-240 © 2015 JEZS forest disease in Wayanad district of Kerala Received: 18-09-2015 Accepted: 21-10-2015 Prakasan K Prakasan K Abstract Post Graduate and Research As a new challenge to health scenario of Kerala, an outbreak of Kyasanur Forest Disease was reported Dept. of Zoology Maharajas from Wayanad and Malappuram districts of Kerala, India from January to March 2015. A study on tick College Ernakulam Kerala- vectors of Wayanad district confirmed the presence of larval and nymphal Haemaphysalis spinigera, the 682011, India. chief vector of KFD in the forest pastures of Pulppally area. But in other sites viz Kalpetta and Mananthavady its prevalence was found to be low. Presence of tick species like Haemaphysalis bispinosa, Haemaphysalis spinigera, Amblyomma integrum. and Boophilus(Rhipicephalus) annulatus. was also noticed from the host animals surveyed. Keywords: Kyasanur Forest Disease, Ixodid ticks, Ectoparasite, Haemaphysalis Kyasanur Forest Disease (KFD) 1. Introduction Kyasanur Forest Disease (KFD), also referred to as monkey fever is an infectious bleeding disease in monkey and human caused by a highly pathogenic virus called KFD virus. It is an acute prostrating febrile illness, transmitted by infective ticks, especially, Haemaphysalis spinigera. Later KFD viruses also reported from sixteen other species of ticks. Rodents, Shrews, Monkeys and birds upon tick bite become reservoir for this virus. This disease was first reported from the Shimoga district of Karnataka, India in March 1955. Common targets of the virus among monkeys are langur (Semnopithecus entellus) and bonnet monkey (Macaca radiata). -
Baseline Mapping of Severe Fever with Thrombocytopenia Syndrome Virology, Epidemiology and Vaccine Research and Development ✉ Nathen E
www.nature.com/npjvaccines REVIEW ARTICLE OPEN Baseline mapping of severe fever with thrombocytopenia syndrome virology, epidemiology and vaccine research and development ✉ Nathen E. Bopp1,8, Jaclyn A. Kaiser2,8, Ashley E. Strother1,8, Alan D. T. Barrett1,2,3,4 , David W. C. Beasley 2,3,4,5, Virginia Benassi 6, Gregg N. Milligan2,3,4,7, Marie-Pierre Preziosi6 and Lisa M. Reece 3,4 Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly emergent tick-borne bunyavirus first discovered in 2009 in China. SFTSV is a growing public health problem that may become more prominent owing to multiple competent tick-vectors and the expansion of human populations in areas where the vectors are found. Although tick-vectors of SFTSV are found in a wide geographic area, SFTS cases have only been reported from China, South Korea, Vietnam, and Japan. Patients with SFTS often present with high fever, leukopenia, and thrombocytopenia, and in some cases, symptoms can progress to severe outcomes, including hemorrhagic disease. Reported SFTSV case fatality rates range from ~5 to >30% depending on the region surveyed, with more severe disease reported in older individuals. Currently, treatment options for this viral infection remain mostly supportive as there are no licensed vaccines available and research is in the discovery stage. Animal models for SFTSV appear to recapitulate many facets of human disease, although none of the models mirror all clinical manifestations. There are insufficient data available on basic immunologic responses, the immune correlate(s) of protection, and the determinants of severe disease by SFTSV and 1234567890():,; related viruses. -
Interrupted Blood Feeding in Ticks: Causes and Consequences
University of Rhode Island DigitalCommons@URI Plant Sciences and Entomology Faculty Publications Plant Sciences and Entomology 2020 Interrupted Blood Feeding in Ticks: Causes and Consequences Djamel Tahir Leon Meyer Josephus Fourie Frans Jongejan Thomas N. Mather University of Rhode Island, [email protected] See next page for additional authors Follow this and additional works at: https://digitalcommons.uri.edu/pls_facpubs Citation/Publisher Attribution Tahir, D.; Meyer, L.; Fourie, J.; Jongejan, F.; Mather, T.; Choumet, V.; Blagburn, B.; Straubinger, R.K.; Varloud, M. Interrupted Blood Feeding in Ticks: Causes and Consequences. Microorganisms 2020, 8, 910. Available at: https://doi.org/10.3390/microorganisms8060910 This Article is brought to you for free and open access by the Plant Sciences and Entomology at DigitalCommons@URI. It has been accepted for inclusion in Plant Sciences and Entomology Faculty Publications by an authorized administrator of DigitalCommons@URI. For more information, please contact [email protected]. Authors Djamel Tahir, Leon Meyer, Josephus Fourie, Frans Jongejan, Thomas N. Mather, Valérie Choumet, Byron Blagburn, Reinhard K. Straubinger, and Marie Varloud This article is available at DigitalCommons@URI: https://digitalcommons.uri.edu/pls_facpubs/36 Review Interrupted Blood Feeding in Ticks: Causes and Consequences Djamel Tahir 1, Leon Meyer 1, Josephus Fourie 2, Frans Jongejan 3, Thomas Mather 4, Valérie Choumet 5, Byron Blagburn 6, Reinhard K. Straubinger 7 and Marie Varloud 8,* 1 Clinvet Morocco, -
Emergence and Resurgence of Zoonotic Infectious Diseases
WellBeing International WBI Studies Repository 2007 The Human/Animal Interface: Emergence and Resurgence of Zoonotic Infectious Diseases Michael Greger The Humane Society of the United States Follow this and additional works at: https://www.wellbeingintlstudiesrepository.org/acwp_tzd Part of the Animal Studies Commons, Other Animal Sciences Commons, and the Veterinary Infectious Diseases Commons Recommended Citation Greger, M. (2007). The human/animal interface: emergence and resurgence of zoonotic infectious diseases. Critical Reviews in Microbiology, 33(4), 243-299. This material is brought to you for free and open access by WellBeing International. It has been accepted for inclusion by an authorized administrator of the WBI Studies Repository. For more information, please contact [email protected]. The Human/Animal Interface: Emergence and Resurgence of Zoonotic Infectious Diseases Michael Greger The Humane Society of the United States CITATION Greger, M. (2007). The human/animal interface: emergence and resurgence of zoonotic infectious diseases. Critical reviews in microbiology, 33(4), 243-299. KEYWORDS agriculture, Avian Influenza, Borrelia burgdorferi, Bovine Spongiform Encephalopathy, bushmeat, Campylobacter; concentrated animal feeding operations, deltaretroviruses, disease ecology, disease evolution, domestic fowl, emerging infectious diseases, Escherichia coli O157, extraintestinal pathogenic Escherichia coli, farm animals, HIV, Influenza A Virus Subtype H5N1, Listeria monocytogenes, multiple drug resistance, Nipah -
The Tick Genera Haemaphysalis, Anocentor and Haemaphysalis
3 CONTENTS GENERAL OBSERVATIONS 4 GENUS HAEMAPHYSALIS KOCH 5 GENUS ANOCENTOR SCHULZE 30 GENUS COSMIOMMA SCHULZE 31 GENUS DERMACENTOR KOCH 31 REFERENCES 44 SUMMARY A list of subgenera, species and subspecies currently included in the tick genera Haemaphysalis, Anocentor and Cosmiomma, Dermacentor is given in this paper; included are also the synonym(s) and the author(s) for each species. Future volume will include the tick species for all remaining genera. Key-Words : Haemaphysalis, Anocentor, Cosmiomma, Dermacentor, species, synonyms. RESUMEN En este articulo se proporciona una lista de los subgéros, especies y subespecies de los géneros de garrapatas Haemaphysalis, Anocentor, Cosmiomma y Dermacentor. También se incluyen la(s) sinonimia(s) y autor(es) para cada especie. En futuros volùmenes se inclura las especies de garrapatas de los restantes géneros. Palabras-Clave : Haemaphysalis, Anocentor, Cosmiomma, Dermacentor, especies, sinonimias. 4 GENERAL OBSERVATIONS Following is a list of species and subspecies of ticks described in the genera Haemaphysalis, Anocentor, Cosmiomma, and Dermacentor. Additional volumes will include tick species for all the remaining genera. The list is intended to include synonyms for the species, as currently considered. For each synonym, date, proposed or used name, and author, are included. For species and subspecies, the basic information regarding author, publication, and date of publication is given, and also the genus in which the species or subspecies have been placed. The complete list of references is included at the end of the paper. If the original paper and/or specimens have not been directly observed by myself, an explanatory note about the paper proposing the new synonym is included. -
Supporting Information
Supporting Information Rosenberg et al. 10.1073/pnas.1307243110 SI Results and Discussion domestic ungulates (horses, cows, sheep, goats, camels, and pigs) Of the 83 arboviruses, nonhuman vertebrate hosts have been and rodents in both groups might be a consequence of spatial identified for 70 (84%); the remaining 13 are presumed to be proximity to humans. Sentinel monkeys were often used in pro- zoonoses because there is no indication they can be transmitted cedures to isolate arboviruses, which might account for their directly between humans by vectors (Table S1). Animal hosts have higher representation among arboviruses. In contrast, there are been identified for at least 57 (44%) of the 130 nonarboviruses; an few published records of bats being routinely sampled during additional 5 (8%) are presumed on epidemiological evidence to arbovirus studies, and only two arboviruses (3%) have been iso- have nonhuman reservoirs (Table S1). A number of viruses infect lated from bats. The reason a much larger number of arbovirus more than one nonhuman vertebrate host species and it is likely species (n = 16) have been isolated from birds than have that the variety of hosts is wider than has been recorded. The nonarbovirus species (n = 1) might, however, be characteristic of predominant host groups for arboviruses (n = 70) are nonhuman the pathogenicity of the togaviruses and flaviviruses, which are primates (31%), rodents (29%), ungulates (26%), and birds (23%); much more common among the arboviruses. The most prominent for the nonarboviruses (n = 57), they are rodents (30%), ungu- vectors of arboviruses were mosquitoes (67%), ticks (19%), and lates (26%), bats (23%), and primates (16%). -
Species Composition of Hard Ticks (Acari: Ixodidae) on Domestic Animals and Their Public Health Importance in Tamil Nadu, South India
Acarological Studies Vol 3 (1): 16-21 doi: 10.47121/acarolstud.766636 RESEARCH ARTICLE Species composition of hard ticks (Acari: Ixodidae) on domestic animals and their public health importance in Tamil Nadu, South India Krishnamoorthi RANGANATHAN1 , Govindarajan RENU2 , Elango AYYANAR1 , Rajamannar VEERAMANO- HARAN2 , Philip Samuel PAULRAJ2,3 1 ICMR-Vector Control Research Centre, Puducherry, India 2 ICMR-Vector Control Research Centre Field Station, Madurai, Tamil Nadu, India 3 Corresponding author: [email protected] Received: 8 July 2020 Accepted: 4 November 2020 Available online: 27 January 2021 ABSTRACT: This study was carried out in Madurai district, Tamil Nadu State, South India. Ticks were collected from cows, dogs, goats, cats and fowls. The overall percentage of tick infestation in these domestic animals was 21.90%. The following ticks were identified: Amblyomma integrum, Haemaphysalis bispinosa, Haemaphysalis paraturturis, Haemaphy- salis turturis, Haemaphysalis intermedia, Haemaphysalis spinigera, Hyalomma anatolicum, Hyalomma brevipunctata, Hy- alomma kumari, Rhipicephalus turanicus, Rhipicephalus haemaphysaloides and Rhipicephalus sanguineus. The predomi- nant species recorded from these areas is R. sanguineus (27.03%) followed by both R (B.) microplus (24.12%) and R. (B.) decoloratus (18.82%). The maximum tick infestation rate was recorded in animals from rural areas (25.67%), followed by semi-urban (21.66%) and urban (16.05%) areas. This study proved the predominance of hard ticks as parasites on domestic animals and will help the public health personnel to understand the ground-level situation and to take up nec- essary control measures to prevent tick-borne diseases. Keywords: Ticks, domestic animals, Ixodidae, prevalence. Zoobank: http://zoobank.org/D8825743-B884-42E4-B369-1F16183354C9 INTRODUCTION longitude is 78.0195° E. -
Arboviruses of Human Health Significance in Kenya Atoni E1,2
Arboviruses of Human Health significance in Kenya Atoni E1,2#, Waruhiu C1,2#, Nganga S1,2, Xia H1, Yuan Z1 1. Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China 2. University of Chinese Academy of Sciences, Beijing, 100049, China #Authors contributed equally to this work Correspondence: Zhiming Yuan, [email protected]; Tel.: +86-2787198195 Summary In tropical and developing countries, arboviruses cause emerging and reemerging infectious diseases. The East African region has experienced several outbreaks of Rift valley fever virus, Dengue virus, Chikungunya virus and Yellow fever virus. In Kenya, data from serological studies and mosquito isolation studies have shown a wide distribution of arboviruses throughout the country, implying the potential risk of these viruses to local public health. However, current estimates on circulating arboviruses in the country are largely underestimated due to lack of continuous and reliable countrywide surveillance and reporting systems on arboviruses and disease vectors and the lack of proper clinical screening methods and modern facilities. In this review, we discuss arboviruses of human health importance in Kenya by outlining the arboviruses that have caused outbreaks in the country, alongside those that have only been detected from various serological studies performed. Based on our analysis, at the end we provide workable technical and policy-wise recommendations for management of arboviruses and arboviral vectors in Kenya. [Afr J Health Sci. 2018; 31(1):121-141] and mortality. Recently, the outbreak of Zika virus Introduction became a global public security event, due to its Arthropod-borne viruses (Arboviruses) are a cause ability to cause congenital brain abnormalities, of significant human and animal diseases worldwide. -
Tick Cell Lines for Study of Crimean-Congo Hemorrhagic Fever
Edinburgh Research Explorer Tick Cell Lines for Study of Crimean-Congo Hemorrhagic Fever Virus and Other Arboviruses Citation for published version: Sakyi, L, Kohl, A, Bente, DA & Fazakerley, JK 2012, 'Tick Cell Lines for Study of Crimean-Congo Hemorrhagic Fever Virus and Other Arboviruses', Vector-Borne and Zoonotic Diseases, vol. 12, no. 9, pp. 769-781. https://doi.org/10.1089/vbz.2011.0766 Digital Object Identifier (DOI): 10.1089/vbz.2011.0766 Link: Link to publication record in Edinburgh Research Explorer Document Version: Peer reviewed version Published In: Vector-Borne and Zoonotic Diseases General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights. Take down policy The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer content complies with UK legislation. If you believe that the public display of this file breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. Download date: 26. Sep. 2021 7/9/13 Tick Cell Lines for Study of Crimean-Congo Hemorrhagic Fever Virus and Other Arboviruses VECTOR BORNE AND ZOONOTIC DISEASES Vector Borne Zoonotic Dis. 2012 September; 12(9): 769–781. PMCID: PMC3438810 doi: 10.1089/vbz.2011.0766 Tick Cell Lines for Study of Crimean-Congo Hemorrhagic Fever Virus and Other Arboviruses Lesley Bell-Sakyi, 1,* Alain Kohl,1,* Dennis A. -
Diversity and Evolutionary Origin of the Virus Family Bunyaviridae
Diversity and Evolutionary Origin of the Virus Family Bunyaviridae Dissertation zur Erlangung des Doktorgrades (Dr. rer. nat.) der Mathematisch-Naturwissenschaftlichen Fakultät der Rheinischen Friedrich-Wilhelms-Universität Bonn vorgelegt von Marco Marklewitz aus Hannover Bonn, 2016 Angefertigt mit Genehmigung der Mathematisch-Naturwissenschaftlichen Fakultät der Rheinischen Friedrich-Wilhelms-Universität Bonn 1. Gutachter: Prof. Dr. Christian Drosten 2. Gutachter: Prof. Dr. Bernhard Misof Tag der Promotion: 21.12.2016 Erscheinungsjahr: 2017 Danksagung Zu Beginn möchte ich mich ganz herzlich bei meinem Doktorvater Prof. Christian Drosten bedanken, dass er mir ermöglicht hat, an einem solch vielfältigen und spannenden Thema zu arbeiten. Für Fragen hatte er jederzeit ein offenes Ohr und bei auftretenden Problemen war er immer sehr hilfsbereit. Des Weiteren möchte ich mich herzlich bei meiner Prüfungskommission, bestehend aus meinem 2. Gutachter Prof. Bernhard Misof sowie Prof. Clemens Simmer und PD Dr. Lars Podsiadlowski, für ihre Zeit und Bereitschaft danken mich zu prüfen. Mein ganz besonder Dank geht an PD Dr. Sandra Junglen für ihre hervorragende und kompetente Betreuung während der Jahre meiner Doktorarbeit. Ich habe es als eine Ehre empfunden, ein Teil ihrer zu Beginn noch sehr jungen Arbeitsgruppe zu sein, danke ihr sehr für ihr Vertrauen und hoffe, sie mit meiner (zukünftigen) Arbeit stolz zu machen. Die Atmosphäre in ihrer Arbeitsgruppe ist immer sehr positiv und ermöglicht, die Arbeit mit viel Spaß zu verbinden. Insbesondere möchte ich herausstellen, dass ich ihr für die Möglichkeit besonders dankbar bin, neben meiner Doktorarbeit Feldarbeiten in Panama durchzuführen. Diese Zeit hat mein Leben auf die positivste Art und Weise nachhaltig beeinflusst. Mein großer Dank gilt auch allen Kolleginnen und Kollegen in den Virologie-Laboratorien der Augenklinik für ihre ständige Hilfs- und Diskussionsbereitschaft, ihr Zuhören bei Problemen sowie für ihre Freundschaft über all die Jahre.