NATIONAL INSTITUTES OF HEALTH National Institute

to

Neoplasms

CONVERSION

of

NEOPLASMS BY TOPOGRAPHY AND MORPHOLOGY

from the

INTERNATIONAL CLASSIFICATION OF FOR , SECOND EDITION

to

INTERNATIONAL CLASSIFICATION OF DISEASES FOR ONCOLOGY, THIRD EDITION

Edited by: Constance Percy, April Fritz and Lynn Ries

Cancer Statistics Branch, Division of Cancer Control and Population Sciences

Surveillance, Epidemiology and End Results Program

National Cancer Institute

Effective for cases diagnosed on or after January 1, 2001

TABLE OF CONTENTS

Introduction ...... 1

Morphology Table ...... 7

INTRODUCTION

The International Classification of Diseases for Oncology, Third Edition1 (ICD-O-3) was published by the World Health Organization (WHO) in 2000 and is to be used for coding neoplasms diagnosed on or after January 1, 2001 in the United States. This is a complete revision of the Second Edition of the International Classification of Diseases for Oncology2 (ICD-O-2), which was used between 1992 and 2000.

The topography section is based on the chapter of the current revision of the International Classification of Diseases (ICD), Tenth Revision, just as the ICD-O-2 topography was. There is no change in this Topography section. The morphology section of ICD-O-3 has been updated to include contemporary terminology. For example, the non-Hodgkin section is now based on the World Health Organization Classification of Hematopoietic Neoplasms3. In the process of revising the morphology section, a Field Trial version was published and tested in both the United States and Europe.

Epidemiologists, statisticians, and oncologists, as well as cancer registrars, are interested in studying trends in both incidence and mortality. To be able to compare data over time, it is essential that conversion tables be available so that all data comparably coded. The following conversion (comparison or equivalency) tables convert ICD-O-2 morphology to ICD-O-3 morphology codes.

Since there is no change to the topography of ICD-O-2 and ICD-O-3, no conversion is necessary.

1 CONVERSION OF MORPHOLOGY

These conversion tables include all codes printed in ICD-O-2 as it was published in 1990, matrix terms identified from the SEER public use data file, and terms added to ICD-O-2 in the lymphoma and sections in North America. These additional terms are identified by a pound sign (#) for lymphoma terms used in North America from 1995 to 2000 diagnoses and a double pound (##) for leukemia terms used in North America from 1998 to 2000.

In the morphology conversion table, the two columns on the left show the morphology code from ICD-O-2 and its associated text (terms). The middle column is a flag to indicate whether the ICD-O-2 text should be hand-reviewed for optimal conversion to ICD- O-3. The two columns on the right show the morphology code and terms from ICD-O-3. The majority of morphology codes and terms are the same in both editions. However, sometimes terms were changed, synonyms added, subtracted or modified. The terms associated with each code (column one and column four) are listed in columns two and five as they appear in the appropriate edition.

The following codes for hand review are used:

0 No review required 1 Review required 2 Review optional (for optimal coding)

Code 0 means that there is a one-to-one relationship between the ICD-O-2 code and the ICD-O-3 code and no review of the output is necessary. (See also note under Code 2.)

Code 1 means that there is not a clear one-to-one relationship between the ICD-O-2 code and the ICD-O-3 code, and that review of the narrative text associated with the code i