Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000009765Cyc: Streptomyces avermitilis MA-4680 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari an amino an amino an amino an amino an amino an amino an amino phosphate acid acid acid acid an amino an amino acid acid acid molybdate H + phosphate phosphate an amino an amino + spermidine α α sn-glycerol acid acid H -L- phosphate N-acetyl- -D-glucosamine ammonium ammonium putrescine D-gluconate 3-phosphate acid acid rhamnopyranose N,N'-diacetylchitobiose predicted predicted predicted predicted predicted predicted predicted predicted predicted ABC ABC ABC ABC ABC ABC ABC ABC ABC F0F1 ATP RS01065 RS27590 RS27105 FtsE RS25690 RS15815 RS14880 RS31535 RS31185 RS22825 RS14810 RS21405 RS20255 RS19445 RS06595 RS38395 RS38070 RS17995 RS36155 RS35865 YajC RS13495 RS17430 RS34865 RS05340 RS30815 RS17350 RS30720 RS30620 MycP RS30540 RS17195 RS30425 RS09640 RS34480 RS30245 RS30145 TatC RS17025 RS30065 RS30025 RS29890 RS34270 RS34265 RS01370 RS34205 RS34190 RS13090 RS29210 RS29140 RS01145 RS09170 RS29000 RS29060 RS34040 RS09180 RS29175 RS29425 RS16835 RS34195 RS13500 RS34055 RhaS RS20995 RS21000 RS33005 NgcE RS13800 RS28865 UgpC RS34500 RS30430 RS05155 RS24790 transporter transporter transporter transporter RS01425 RS36230 RS06090 transporter transporter transporter PntB RS36735 RS37665 RS18340 RS18555 RS11460 RS20065 MurJ RS21690 MurJ RS23120 RS15340 RS24375 RS25255 RS32425 RS26130 RS26665 RS16320 RS16450 transporter transporter synthase of an of an of an of an of an of an of an of molybdate of phosphate amino acid amino acid amino acid amino acid amino acid amino acid amino acid α-L- N-acetyl-α-D-glucosamine an amino an amino H + spermidine D-gluconate phosphate phosphate sn-glycerol H + rhamnopyranose phosphate N,N'-diacetylchitobiose ammonium ammonium an amino an amino acid acid putrescine 3-phosphate acid acid molybdate phosphate an amino an amino an amino an amino an amino an amino an amino acid acid acid acid acid acid acid

chaplin Cofactor, Carrier, and Vitamin Biosynthesis Aromatic Compound Amine and Polyamine Degradation Biosynthesis Macromolecule Modification tRNA processing ditrans,octacis- UDP-N-acetyl- a nascent Nα,Nε-diacetyl-lysyl- UDP-N-acetyl- (4R)-4-hydroxy- a [DNA]-3'- a 5'-phospho- phosphoenol 5-deoxy-D- 5-methoxybenzimidazole NaMN a purine menadione NADH H + meso- 3-phenylpropanoate a [glutamine- a lipid II formaldehyde predicted cob(II)yrinate a,c- Fatty Acid and Lipid Biosynthesis ethanolamine utilization adenosylcobinamide undecaprenyldiphospho- α-D-muramoyl-L- peptidoglycan α-D-muramoyl- 2-oxoglutarate glucuronate cob(II)yrinate a,c-diamide [2Fe-2S] iron-sulfur superpathway of coenzyme A biosynthesis I (bacteria) thiamine diphosphate NAD de novo biosynthesis adenosylcobalamin thiamine diphosphate salvage II mycothiol biosynthesis adeninyl adenosylcobamide biosynthesis NAD de novo biosynthesis chorismate biosynthesis I a polycistronic putrescine degradation IV superpathway of putrescine degradation I 4-aminobutanoate urea degradation II ribonucleoside diaminopimelate D-alanyl-D-alanine ATP synthetase]- hydroxyl [DNA] dGDP pyruvate dGDP dADP ABC diamide biosynthesis I from adenosylcobinamide-GDP I (from aspartate) allantoin degradation N-acetyl-(N-acetyl-β-D- alanyl-D-glutamate (meso-DAP bifunctional 3- L-alanyl-γ-D- glutathione- 5-deoxy- urea urea biosynthesis II (late cluster biosynthesis biosynthesis I (E. coli) II (from tryptophan) salvage from cobalamin tRNA precursor 4-aminobutanoate degradation III 5'-triphosphate L-tyrosine vitamin B12- transporter RS04910 (early cobalt insertion) 3-methyl-2- a 5,10- palmitate biosynthesis (type II fatty acid synthase) D-erythrose ethanolamine to ureidoglycolate II glucosaminyl)muramoyl- containing) phenylpropionate/ glutamyl-meso-2,6- independent vitamin B12- glucuronate cobalt incorporation) 4-amino-2-methyl-5- D-glucopyranose octanoyl-[acyl-carrier CDP-diacylglycerol putrescine degradation nicotinate-nucleotide-- D-alanyl-D-alanine D-alanyl-D-alanine bifunctional non- dependent of urea uroporphyrinogen-III oxobutanoate methylenetetrahydrofolate 2-[(2R,5Z)- 4-phosphate (ammonia producing) putrescine urea D-aspartate L-alanyl-γ-D-glutamyl-L- NADH-quinone cinnamic acid diaminopimeloyl- formaldehyde dependent isomerase: uroporphyrinogen-III L-cysteine desulfurase 2-carboxy-4- trp cob(I)alamin pyrimidinemethanol 6-phosphate asp protein] biosynthesis biosynthesis I 3-deoxy-7- 4-aminobutanoate 4-aminobutanoate dimethylbenzimidazole bifunctional oxidoreductase: UDP-N- carboxypeptidase/ carboxypeptidase/ 4-hydroxy-2- homologous ribonucleotide iolB bifunctional adenine ethanolamine (S)-(+)-allantoin urease: lysyl-D-alanyl-D-alanine dioxygenase D-alanyl-D-alanine bifunctional [glutamine dehydrogenase: pyruvate ribonucleotide acetate acetate bifunctional methylthiazol-5(2H tryptophan 2,3- bifunctional inositol-3-phosphate L-aspartate oxidase: an acetoacetyl-[acp] (mitochondria, yeast) phosphoheptulonate 4-aminobutyrate- 4-aminobutyrate- phosphoribosyltransferase: adenosylcobinamide SAVERM_RS24960 acetylmuramoyl-L- lytic transglycosylase D-alanyl-D-alanine- D-alanyl-D-alanine- oxoglutarate end-joining reductase: uroporphyrinogen-III 3-methyl-2-oxobutanoate ammonia-lyase: allantoinase SAVERM_RS14155 ferredoxin subunit: synthetase] SAVERM_RS37135 kinase: pyk reductase: 5-deoxy- uroporphyrinogen-III cysteine desulfurase: )-ylidene]ethyl dioxygenase: hydroxymethylpyrimidine synthase: SAVERM_RS24200 DHAP synthase class II: -2-oxoglutarate -2-oxoglutarate cobT kinase/ SAVERM_RS24970 alanyl-D-glutamate-- domain-containing endopeptidase: dacB endopeptidase: dacB aldolase/2- DNA SAVERM_RS12835 RS36145 RS06130 C-methyltransferase/ hydroxymethyltransferase: HMP-PP nicotinate-nucleotide-- an acetoacetyl-[acp] a tRNA precursor SAVERM_RS23480 AllB: allB 4-aminobutanal ureA SAVERM_RS32545 adenylyltransferase/ glutathione- pyruvate SAVERM_RS12835 glucuronate a metal a metal C-methyltransferase/ SAVERM_RS32555 phosphate SAVERM_RS23380 cob(II)alamin kinase/ SAVERM_RS22210 2-iminosuccinate 3-oxoacyl-[acyl- glycerol-3-phosphate SAVERM_RS31350 ribonuclease D: transaminase: transaminase: adenosylcobinamide- D-aspartate ligase: SAVERM_RS24975 nuoE 2, 6-diaminopimelate protein: D-alanyl-D-alanine penicillin- dehydro-3-deoxy- ligase: ligD uroporphyrinogen- panB N-Formyl-L- dimethylbenzimidazole 3-oxoacyl-[acyl- 3-deoxy- with a 5' extension eutC urease: nicotinate-nucleotide-- penicillin- bifunctional 3- [glutamine synthetase]- independent kinase: pyk ribonucleoside- isomerase: cation cation uroporphyrinogen- [+ 2 isozymes] phosphomethylpyrimidine carrier-protein] dehydrogenase: SAVERM_RS11695 allantoate 4-aminobutanal gabT gabT phosphate SAVERM_RS25075 nuoF SAVERM_RS24990 ligase: SAVERM_RS30135 carboxypeptidase/ binding phosphogluconate [+ 3 isozymes] ribonucleoside- sulfite RS08495 sulfite III synthase: kynurenine phosphoribosyltransferase: carrier-protein] D-arabino- and a long 3' trailer a tRNA precursor with succinate gamma- succinate SAVERM_RS36495 dimethylbenzimidazole binding phenylpropionate/ adenylyl-L-tyrosine formaldehyde diphosphate iolB III synthase: thiamine phosphate cob(I)yrinic acid kinase: thiD Ins(3)P UDP-N-acetyl- quinolinate reductase: fabG SAVERM_RS13950 acetaldehyde guanylyltransferase: nuoH nuoI SAVERM_RS31505 [+ 5 isozymes] D-alanyl-D-alanine- protein aldolase: eda diphosphate 5-dehydro- SAVERM_RS24485 an S-sulfanyl-[L- α cobT reductase: fabG sn-glycerol heptulosonate a 5' extension and allantoate semialdehyde aminobutyraldehyde semialdehyde SAVERM_RS36500 phosphoribosyltransferase: protein cinnamic acid phosphorylase: dehydrogenase: reductase: SAVERM_RS24485 2-dehydropantoate synthase: a,c-diamide -D-glucosamine synthase 3-oxoacyl-[acyl- ribonuclease SAVERM_RS31080 SAVERM_RS25005 nuoK endopeptidase: dacB 2: mrdA reductase: 2-deoxy-D- cysteine desulfurase] HMP-P nicotinate-nucleotide-- 3-phosphate 7-phosphate a short 3' extension amidohydrolase: gamma- dehydrogenase: SAVERM_RS36505 cobT ditrans,octacis- 2: mrdA dioxygenase SAVERM_RS30780 SAVERM_RS05300 pyruvate SAVERM_RS15715 RS38495 uroporphyrinogen-III SAVERM_RS31415 adenosyltransferase: NadA: nadA carrier-protein] 3-oxoacyl-[acyl- PH: rph succinate- SAVERM_RS25020 nuoN UDP-N-acetyl- a mature a nascent penicillin- [DNA] dGTP SAVERM_RS15715 gluconate uroporphyrinogen-III D-inositol-3-phosphate dimethylbenzimidazole 3-dehydroquinate ribonuclease ethanol SAVERM_RS18060 aminobutyraldehyde SAVERM_RS04405 ammonium adenosyl- undecaprenyldiphospho-N- ferredoxin subunit: SAVERM_RS15720 C-methyltransferase: 2-dehydropantoate SAVERM_RS14935 reductase: fabG carrier-protein] ribonuclease D:polyribonucleotide semialdehyde α-D-muramoyl- peptidoglycan peptidoglycan binding glyoxylate pyruvate formate SAVERM_RS15720 sulfite RS33810 sulfite C-methyltransferase: asp 5-(2-hydroxyethyl) bifunctional glycosyltransferase: phosphoribosyltransferase: quinolinate synthase: ribonuclease D: P protein dehydrogenase: dehydrogenase: [+ 2 isozymes] allantoin degradation cobinamide acetyl-(N-acetylglucosaminyl) NADH-quinone α ε SAVERM_RS35725 a N- GDP ADP cobA 2-reductase: superpathway of tetrahydrofolate biosynthesis L-kynurenine cob(I)yrinic acid reductase: fabG SAVERM_RS11695nucleotidyltransferase: (S)-ureidoglycine 1-pyrroline dehydrogenase 5-methoxybenzimidazole nicotinate a purine L-alanyl-γ-D- with (L-alanyl- (meso-DAP N ,N -diacetyl- 3-(5,6- protein a [glutamine cobA thiamine -4-methylthiazole hydroxymethylpyrimidine mshA cobT a (3R)-3- a (3R)-3- SAVERM_RS35235 SAVERM_RS11695 component: SAVERM_RS35715 SAVERM_RS04405 succinate to ureidoglycolate phosphate muramoyl-L-alanyl-γ-D- oxidoreductase D-ala D-ala acetylglucosamine- precorrin-1 an S-sulfanyl-[cysteine SAVERM_RS09670 a,c-diamide carboxylating a 1-acyl-sn SAVERM_RS13170 (NADP(+)): 4-aminobutanoate ribotide phosphate ribonucleoside glutamyl-meso-2,6- γ-D-glutamyl- containing) with lysyl-D-alanine dihydroxycyclohexa-1,3- 2: mrdA synthetase]-O precorrin-1 aspartate 1- phosphate kinase/ hydroxybutanoyl-[acp] rnpA acetyl-CoA β 4 -N-acetylmuramyl- 2-dehydropantoate hydroxybutanoyl-[acp] 3-dehydroquinate [+ 2 isozymes] SAVERM_RS25870 I (urea producing) glutamyl-N-( -D-asparatyl) subunit NuoK: nuoK -(5'-adenylyl) chaplin desulfurase]-[disordered- decarboxylase: adenosyltransferase: phosphomethylpyrimidine 1-O-(2-acetamido- adenine ribotide nicotinate-nucleotide -glycerol 3- C1 Compound Utilization and Assimilation 5'-diphosphate diaminopimelate meso-2,6- GlcNAc terminus dien-1-yl)propanoate (tetrapeptide) bifunctional 2-reductase: thiamine- 3-hydroxyacyl- 3-hydroxyacyl- a tRNA precursor with ethanol -L-lysyl-D-alanyl-D-alanine -L-tyrosine bifunctional form scaffold SAVERM_RS37220 GTP cobO kinase: thiD 2-deoxy-α-D- adenosylcobinamide- phosphate diphosphorylase: phosphate phosphate (S)-(+)-allantoin diaminopimeloyl- UDP-N- pyrophosphoryl- RS09860 uroporphyrinogen-III SAVERM_RS30010 phosphate kinase: 4-methyl-5-(2- ACP dehydratase: ACP dehydratase: type II 3- a short 3' extension 4-aminobutanoate succinate uroporphyrinogen-III protein] complex cob(II)alamin- glucopyranosyl)-1D-myo SAVERM_RS24205 1-acyl-sn-glycerol- acetyltransferase: pta allantoinase formaldehyde oxidation + D-alanine) D-ala acetylmuramoyl- undecaprenol C-methyltransferase/ [cysteine desulfurase]-S- SAVERM_RS13930 3-hydroxy- phosphooxyethyl) 1,4-dihydroxy-6- GDP SAVERM_RS18860 dehydroquinate (S)-ureidoglycolate formaldehyde oxidation NAD menadiol C-methyltransferase/ β-alanine GTP [corrinoid HMP-PP -inositol 3-phosphate SAVERM_RS18860 3-phosphate a tRNA precursor AllB: allB VII (THF pathway) tetrapeptide L-alanyl-γ-D- uroporphyrinogen- sulfanylcysteine:[acceptor (R)-pantoate thiamine L-kynurenine thiazole naphthoate biosynthesis I NaMN dehydratase: aroQ V (bacillithiol-dependent) uroporphyrinogen- cyclohydrolase adenosyltranferase] a (2E)-but-2-enoyl-[acp] acyltransferase: with a 5' extension acetyl phosphate allantoate glutamyl-meso-2,6- RS11320 III synthase: protein]-cysteine diphosphate adenosylcobinamide- a (2E)-but-2-enoyl-[acp] III synthase: I FolE: folE menaquinol-6 biosynthesis SAVERM_RS31320 3-dehydroshikimate ribonuclease ribonuclease D: formaldehyde diaminopimeloyl- SAVERM_RS24485 sulfurtransferase: kynureninase: thiamine phosphate chorismate GDP nicotinate-nucleotide formaldehyde SAVERM_RS24485 pantoate--beta- 7,8- acyl-CoA/acyl-ACP [+ 6 isozymes] PH: rph SAVERM_RS11695 acetate kinase: allantoicase: D-alanine SAVERM_RS14355 kynU synthase: 1-(2-acetamido- ribazoletransferase: benzimidazolyl adenosylcobamide adenylyltransferase: enoyl-ACP ribonuclease RS01105 uroporphyrinogen-III alanine ligase: dihydroneopterin cob(I)alamin- dehydrogenase: a 1,2-diacyl- shikimate SAVERM_RS14690 alc uroporphyrinogen-III a [cysteine desulfurase]- SAVERM_RS31415 demethylmenaquinol-6 2-deoxy-α-D- SAVERM_RS31050 biosynthesis from adenosylcobinamide-GDP SAVERM_RS28275 reductase P protein C-methyltransferase: SAVERM_RS24195 3'-triphosphate 3-hydroxyanthranilate [corrinoid SAVERM_RS22490 sn-glycerol dehydrogenase: a 5,10- C-methyltransferase: S-sulfanyl-[disordered- demethylmenaquinone glucopyranosyl)- nicotinate adenine FabI: fabI component: S-(hydroxymethyl) a methylated UDP-N-acetyl-α-D- N-acetyl-muramoyl-(L- a DNA containing an sn-glycero-3- a [bis(guanylyl a [glutamine a peptide with RS14545 cobA adenosyltranferase] 3-[(1- Coα-[α-(adenin-9-yl)]- [+ 9 isozymes] 3-phosphate SAVERM_RS09380 acetate (S)-ureidoglycolate methylenetetrahydrofolate a [2-oxoglutarate dehydrogenase E2 hydrogen a reduced an L-asparaginyl- an L-cysteinyl- phosphoenol cobA form scaffold thiamine methyltransferase: 1D-myo-inositol benzimidazole dinucleotide [+ 2 isozymes] rnpA bacillithiol 5-hydroxybenzimidazole NaMN 6 2-oxoglutarate nucleobase muramoyl-L-alanyl- alanyl-γ-D-glutamyl-L- an apurinic/ phospho-N-(acyl) molybdopterin) glycerophosphoserine synthetase]-O an N-terminal 5-MTR-1-P a protein Coβ-adenosylcobamide phosphatidate shikimate ATP biosynthesis protein] N -dihydrolipoyl-L-lysine cys peroxide Asn Cys ATP roseoflavin dADP pyruvate protein] complex (R)-pantothenate cob(I)yrinic acid carboxyvinyl) bifunctional 5,10- γ 4 thioredoxin [tRNA ] [tRNA ] precorrin-2 phosphate SAVERM_RS24930 N-acetyl-1-D-myo- cytidylyltransferase: S-(hydroxymethyl) 2-oxoglutarate within DNA -D-glutamyl-meso- lysyl-D-alanyl-D-alanine) apyrimidinic site ethanolamine cofactor -(5'-adenylyl) L-methionine S-methyl-5- proteasome precorrin-2 cysteine desulfurase: 7,8- a,c-diamide menaquinol-6 oxy]benzoate 5'-phosphate nicotinate-nucleotide-- NAD+ synthase: NAD+ synthase: a butanoyl-[acp] dehydrogenase: methylenetetrahydrofolate D-alanyl-D-alanine 5'-phosphate inositol-2-amino- a butanoyl-[acp] SAVERM_RS13660 mycothiol dehydrogenase, 2,6-diaminopimelate chaperone]- -L-tyrosine thioribose-1- subunit RS04390 precorrin-2 SAVERM_RS32555 type III pantothenate dihydroneopterin 2-amino-3- adenosyltransferase: thiamine- aminofutalosine dimethylbenzimidazole SAVERM_RS30660 SAVERM_RS30660 SAVERM_RS35220 ADP dehydrogenase/5,10- nicotinate-nucleotide-- precorrin-2 C(20)- 2-deoxy-alpha- D- beta-ketoacyl- dehydrogenase: E2 component, alpha-ketoglutarate- L-cysteine glycerophosphoryl thioredoxin- phosphate beta: prcB dehydrogenase: [+ 2 isozymes] kinase: 3'-phosphate carboxymuconate- SAVERM_RS14935 phosphate kinase: synthase phosphoribosyltransferase: beta-ketoacyl- a CDP- F0F1 ATP synthase: methenyltetrahydrofolate dimethylbenzimidazole D-alanyl-D-alanine endonuclease glycerophosphoryl peptidyl-tRNA peptidyl-tRNA type I methionyl RS21745 methyltransferase: an S-sulfanyl-[cysteine chorismate glucopyranoside NAD + shikimate SAVERM_RS35715 dihydrolipoamide dependent diester dependent bifunctional pyruvate cobA SAVERM_RS24210 6-semialdehyde SAVERM_RS13930 MqnE: mqnE ACP synthase diacylglycerol an uncharged tRNA SAVERM_RS14965 Inorganic Nutrient Metabolism cyclohydrolase: UDP-N- carboxypeptidase/ III: nth diester bifunctional [glutamine hydrolase: hydrolase: aminopeptidase: isomerase: proteasome: cobI desulfurase]-S- cob(I)yrinic acid deacetylase: mshB Coα-[α-(adenin-7-yl)]- cobT ACP synthase phosphoribosyltransferase: succinyltransferase: sucB dioxygenase AlkB: phosphodiesterase thiol riboflavin kinase/ kinase: pyk aminodeoxychorismate thiamine II: fabF atpD SAVERM_RS03205 S-formylbacillithiol acetylmuramoyl- D-alanyl-D-alanine- bifunctional DNA- phosphodiesterase cysteine synthetase] SAVERM_RS11620 SAVERM_RS11620 map mtnA prcB prcA sirohydrochlorin sulfanyl-[disordered- type I pantothenate a,c-diamide 6-amino-6- Coβ-adenosylcobamide nicotinate-nucleotide-- II: fabF shikimate kinase: cobT SAVERM_RS06145 membrane domain- peroxidase: FAD synthetase: synthase: diphosphate [+ 2 isozymes] SAVERM_RS14975 multifunctional oxoglutarate tripeptide--D-alanyl- endopeptidase: dacB formamidopyrimidine membrane domain- desulfurase adenylyltransferase/ [+ 2 isozymes] [+ 2 isozymes] pyruvate [+ 3 isozymes] S-methyl-5- a peptide precorrin-3A form scaffold kinase: D-erythro-7,8- adenosyltransferase: GlcN-Ins deoxyfutalosine dimethylbenzimidazole [+ 2 isozymes] SAVERM_RS35230 selenate reduction a 5,10- nicotinate-nucleotide-- containing protein: bcp SAVERM_RS13280 SAVERM_RS06370 SAVERM_RS14980 assimilatory dimethyl sulfide urea cycle assimilatory sulfate activation decarboxylase/oxoglutarate alpha-ketoglutarate- D- alanine ligase: penicillin-binding glycosylase/ containing protein: DndA: dndA [glutamine synthetase]- kinase: pyk thioribose-1- RS33830 sirohydrochlorin protein] complex SAVERM_RS25600 dihydroneopterin cobO phosphoribosyltransferase: a 3-oxohexanoyl-[acp] methenyltetrahydrofolate dimethylbenzimidazole SAVERM_RS26110 RS07715 [cysteine desulfurase]-S- quinolinate adenosylcob(III) cysteine--1-D-myo- phosphatidylserine and shikimate 3- SAVERM_RS14985 sulfate reduction IV degradation II (oxidation) sulfate reduction III for sulfonation formaldehyde oxidation dehydrogenase thiamine dependent SAVERM_RS31510 protein 2: mrdA DNA-(apurinic SAVERM_RS26110 adenylyl-L-tyrosine phosphate cobaltochelatase: (R)-4'- aminodeoxychorismate/ cobT a 3-oxohexanoyl-[acp] selenate bifunctional 5,10- phosphoribosyltransferase: [+ 2 isozymes] [+ 7 isozymes] roseoflavin sulfanylcysteine:[acceptor dihydroneopterin alamin-[corrinoid inosityl 2-amino- phosphatidylethanolamine phosphate lipoprotein posttranslational modification SAVERM_RS14990 III (mycothiol-dependent) pyrophosphate-binding dioxygenase AlkB: or apyrimidinic [+ 7 isozymes] phosphorylase: an oxidized H O asn tRNA Asn cys a tRNA Cys met a peptide isomerase: SAVERM_RS32935 phosphopantothenate anthranilate synthase carboxylating benzimidazole 3-oxoacyl-[acyl- sulfate dimethyl sulfide arg sulfate methylenetetrahydrofolate cobT SAVERM_RS07680 2 adenine pyruvate protein]-cysteine aldolase: folB adenosyltranferase] 2-deoxy-alpha-D- demethylmenaquinol- 3-oxoacyl-[acyl- biosynthesis I 3-phosphoshikimate 1- SAVERM_RS14995 sulfate sulfate formate subunit/dihydrolipoyllysine- UDP-N-acetyl-α-D- N-acetyl-muramoyl-(L- site) lyase: mutM a [bis(guanylyl SAVERM_RS30780 thioredoxin dATP mtnA cobalt- bifunctional component II: nicotinate-nucleotide futalosine adenosylcobinamide- ribotide carrier-protein] adenylyltransferase sulfate dehydrogenase/5,10- dinucleotide S-methyl-5- precorrin-3B sulfurtransferase: adenosylcobinamide-GDP cob(I)yrinic acid glucopyranoside 8 biosynthesis II carrier-protein] carboxyvinyltransferase: a [prolipoprotein]- atpB sulfate sulfate formaldehyde residue succinyltransferase muramoyl-L-alanyl- alanyl-γ-D-glutamyl- D-ala ala molybdopterin) sn-glycerol sirohydrochlorin phosphopantothenoylcysteine 6-(hydroxymethyl) SAVERM_RS22415 diphosphorylase: GDP phosphate reductase: fabG a CDP-diacylglycerol subunit CysD: cysD adenylyltransferase methenyltetrahydrofolate sn-glycerol an N- ser thio-D-ribulose RS28055 SAVERM_RS14355 salvage from cobinamide I a,c-diamide ligase: mshC all-trans- reductase: fabG aroA L-cysteine adenylyltransferase adenylyltransferase 5-hydroxybenzimidazole subunit: SAVERM_RS15455 a nucleobase γ-D-glutamyl-meso- L-lysyl-D-alanine) cofactor 3-phosphate a [glutamine- precorrin-3B C(17)- a [cysteine decarboxylase/ -7,8-dihydropterin 4-amino-4- SAVERM_RS24205 futalosine hydrolase: 3-oxoacyl-[acyl- CDP-diacylglycerol--serine subunit CysD: cysD cyclohydrolase: nicotinate a [2-oxoglutarate dehydrogenase E2 formaldehyde succinate a 3'-terminal a 5'-phospho- 3-phosphate acylethanolamine 1-phosphate RS16440 adenosyltransferase: 1,4-dihydroxy- octaprenyl 5-methylbenzimidazolyl adenosylcobamide 5-enolpyruvoyl- prolipoprotein ATP sulfate subunit CysD: cysD dimethyl sulfoxide subunit CysD: cysD ribotide phosphate within DNA 2,6-diaminopimeloyl- chaperone]-S- ADP synthetase]- methyltransferase: desulfurase]-(S- phosphopantothenate-- 2-amino-4-hydroxy-6- deoxychorismate deacetylmycothiol SAVERM_RS20155 adenosylcobinamide- 3-oxoacyl-[acyl- O-phosphatidyltransferase: SAVERM_RS03205 6 unsaturated sugar [DNA] cob(II)inamide 6-naphthoate biosynthesis from adenosylcobinamide-GDP carrier-protein] shikimate 3- diacylglyceryl adenylyltransferase sulfate sulfate sulfate S-(hydroxymethyl) protein] N -S-succinyldihydrolipoyl-L-lysine D-alanyl-D-alanine L-tyrosine cobJ sulfanyl) -[disordered- cysteine ligase CoaBC: coaBC hydroxymethyldihydropteridine NaMN SAVERM_RS14935 diphosphate GDP carrier-protein] pssA sulfanyl-L-cysteine 2 aminodeoxychorismate cob(I)yrinic acid dehypoxanthine reductase: fabG a 3-sn-phosphatidyl- phosphate transferase: subunit CysD: cysD adenylyltransferase adenylyltransferase adenylyltransferase bifunctional mycothiol form scaffold (R)-4'- diphosphokinase: folK cob(I)yrinic acid superpathway of thiamine diphosphate biosynthesis II mycothiol ribazoletransferase: reductase: fabG adenosine 5'- cobalt-factor III lyase: SAVERM_RS34965 nicotinate-nucleotide a,c-diamide futalosine menaquinone 5-methylbenzimidazole a (3R)-3- L-serine chorismate SAVERM_RS31815 subunit CysD: cysD ammonium subunit CysD: cysD subunit CysD: cysD methylenetetrahydrofolate S-(hydroxymethyl) RS28895 RS12940 precorrin-4 protein] complex phosphopantothenoyl- (7,8-dihydropterin- a,c-diamide synthase: SAVERM_RS31050 phosphoselenate di-trans,octa-cis UDP-N-acetyl- a peptidoglycan a peptidoglycan an N-terminal- an N-terminal- a peptide with a (1->4)- adenylyltransferase: adenosyltransferase: dehypoxanthine biosynthesis a (3R)-3- hydroxyhexanoyl-[acp] phosphatidylserine synthase: a [prolipoprotein]- APS argininosuccinate APS APS dehydrogenase/ mycothiol 5-methoxy-6- ditrans,octacis- a 2-oxo sn-glycero-3- a [protein]- 6-yl)methyl mshD NaMN KDGP serotonin MoO - sec L-cysteine adenosyltransferase: a [ThiS sulfur- nicotinate-nucleotide-- hydroxyhexanoyl-[acp] dimethyl sulfone -undecaprenyl α-D-muramoyl- undecaprenyldiphospho-N- dimer (E. faeciums) DL-allothreonine dimer (S. aureus) L-ornithine L-methionyl-L- 2 L-methionyl-L- met an N-terminal ser a tRNA α-D-glucan precorrin-4 C(11)- 4-aminobenzoate SAVERM_RS28275 SAVERM_RS14935 futalosine decarboxylase: Coα-[α- decarboxylase: aroC S-1,2-diacyl-sn- lyase: argH glutamine- methenyltetrahydrofolate dehydrogenase: methylbenzimidazole carboxylate phosphoethanolamine L-glutamine ATP GTP 2-phospho- RS12805 bifunctional diphosphate cobO carrier protein] cys dimethylbenzimidazole 3-hydroxyacyl- adenylyl-sulfate phosphoadenylyl- phosphate L-alanyl-γ-D- acetyl-(N-acetylglucosaminyl) threonyl-[protein] molybdopterin alanyl-[protein] L-alanine 1,4-alpha- methyltransferase: nicotinate adenine cob(I)yrinic acid mycothiol cyclase: mqnC SAVERM_RS24820 (benzimidazolyl)]-Co 3-hydroxyacyl- SAVERM_RS10095 glyceryl-L-cysteine L-arginino- hydrolyzing adenylyl-sulfate cyclohydrolase: SAVERM_RS35715 L-lactate amino-acid N- phosphopantothenoylcysteine phosphoribosyltransferase: ACP dehydratase: chorismate kinase: cysC dimethyl sulfone L-ornithine sulfate reductase: glutamyl-meso-2,6- muramoyl-L-alanyl-γ-D- D-aspartate cofactor glucan cobM a [cysteine desulfurase]- dinucleotide a,c-diamide adenosylcobalamin cyclic β-adenosylcobamide ACP dehydratase: an L-1- succinate carbamoyl- kinase: cysC SAVERM_RS17805 D-alanyl-D-alanine D-alanyl-D-alanine acetyltransferase: cobalt-precorrin-3 decarboxylase/ dihydropteroate flavin biosynthesis I (bacteria and plants) cysteine desulfurase: cobT SAVERM_RS18860 signal peptidase II: selenite monooxygenase SAVERM_RS11185 S-formylmycothiol diaminopimeloyl- nicotinate-nucleotide-- isoglutaminyl-L-lysyl-D-alanine bifunctional ornithine- glycerophosphoryl transglutaminase branching RS27970 [scaffold protein- dehypoxanthine SAVERM_RS18860 adenylyl-sulfate phosphate adenylyl-sulfate polyphosphate 10 carboxypeptidase/ serine carboxypeptidase/ type I methionyl type I methionyl SAVERM_RS24230 aminopeptidase serine--tRNA precorrin-5 phosphopantothenate-- synthase: folP NAD+ synthase: adenosyltransferase: SAVERM_RS32555 demethylmenaquinol-8 5'-phosphate phosphatidylethanolamine SfnG: sfnG an N - D-alanyl-D-alanine dimethylbenzimidazole 4-hydroxy-2- -oxo-acid diester domain-containing molybdenum cofactor 2-phospho-L-lactate enzyme: (2Fe-2S)] complex futalosine nicotinate-nucleotide-- SAVERM_RS31580 kinase: cysC argininosuccinate synthase: sulfite kinase: cysC metabolism D-alanyl-D-alanine- hydroxymethyltransferase: D-alanyl-D-alanine- aminopeptidase: aminopeptidase: bifunctional N: pepN ligase: serS cysteine ligase CoaBC: coaBC dihydropteroate SAVERM_RS30660 [corrinoid cobO a carboxy- a (2E)-hex-2-enoyl-[acp] formyltetrahydrofolate phosphoribosyltransferase: oxoglutarate transaminase: phosphodiesterase protein: guanylyltransferase: guanylyltransferase: glgB a reduced D-glyceraldehyde [+ 2 isozymes] dimethylbenzimidazole a (2E)-hex-2-enoyl-[acp] methanesulfinate synthase: argG carA carB phospho-N- endopeptidase: dacB SAVERM_RS14445 endopeptidase: dacB map map glutamate N- [+ 3 isozymes] serine--tRNA a (1,6)-α-D- precorrin- synthase: folP adenosyltranferase]- adenylated- an [L-cysteine 1,4-dihydroxy-6- long-chain fatty an (S-diacyl-sn- PAPS PAPS long chain formyltetrahydrofolate cobT D-aspartate ligase: aldolase/2- rocD membrane domain- SAVERM_RS31470 SAVERM_RS22570 cofC H O c-type GTP 3-phosphate phosphoribosyltransferase: a lipoprotein argininosuccinate assimilatory sulfite acetylmuramoyl- serine [+ 3 isozymes] [+ 3 isozymes] ligase: serS 2 cytochrome 6A synthase 4'-phosphopantetheine NAD + cob(II)inamide [ThiS sulfur- desulfurase]-S- Coα-[α- acyl-CoA/acyl-ACP acid activation glyceryl)-L-cysteinyl- carbamoyl polyphosphate SAVERM_RS25075 penicillin-binding penicillin- containing protein: transglutaminase: acetyltransferase/ glucosyl-(1,4) cytochrome naphthoate synthase: cobT enoyl-ACP signal peptide synthase: reductase (NADPH): deformylase: purU pentapeptide- nicotinate-nucleotide-- dehydro-3-deoxy- ornithine- α an oxidized cobalt-precorrin-4 (deacetylating) a [co-chaperone]- 7,8- 1-deoxy-D-xylulose-5- carrier protein] sulfanyl-L-cysteine dehydrogenase: [apolipoprotein] selenodiglutathione phosphoadenylyl- ornithine phosphate formate protein 2: mrdA hydroxymethyltransferase: binding SAVERM_RS26110 amino-acid - -glucan c oxidase RS27535 GTP cyclohydrolase SAVERM_RS20160 (benzimidazolyl)]-Co reductase a long-chain SAVERM_RS34805 SAVERM_RS11175 transferase: dimethylbenzimidazole phosphogluconate -oxo-acid SAVERM_RS07900 adenylyl L-lactyl-2- O c-type pantetheine- phosphate synthase: SAVERM_RS22490 sulfate reductase: carbamoyltransferase: SAVERM_RS15105 acetyltransferase ala a peptide 2 : cobF [scaffold protein- dihydropteroate β-adenosylcobamide adenosylcobinamide- 5-methylbenzimidazole fatty acid apolipoprotein N- formate SAVERM_RS31515 phosphoribosyltransferase: protein aldolase: eda [+ 7 isozymes] an N-terminal L- molybdenum diphospho- an N-terminal L- a reduced cobalt precorrin- phosphate II: SAVERM_RS03220 SAVERM_RS08720 gly FabI: fabI long-chain fatty SAVERM_RS11185 SAVERM_RS18795 ditrans,octacis- transaminase: ArgJ: argJ sec cytochrome (2Fe-2S)] complex cysteine desulfurase: ribotide phosphate [+ 9 isozymes] acyltransferase: lnt hydrogen sulfide inorganic undecaprenyldiphospho- UMP a peptidoglycan tetramer 2: mrdA 6 met threonyl-[protein] met alanyl-[protein] an L-seryl-[tRNA ] 11 bifunctional [corrinoid 1,4-dihydroxy- an unknown GDP methanesulfonate cobT a [protein] N - cofactor 5'-guanosine H O c-type 4 (C )- precorrin-6A SSQ1 adenylyltransferase: [+ 3 isozymes] 1-deoxy-D-xylulose-5- [+ 2 isozymes] acid--CoA ligase: ornithine glyphosate polyphosphate/ N-acetylmuramoyl-L- undecaprenyldiphospho-N-acetyl- rocD N-acetyl-L- 2 folylpolyglutamate 2,5-diamino-6- adenosyltranferase]- glycine SAVERM_RS32555 6-naphthoate compound [+ 3 isozymes] sulfite with a D,D cross-link D-ala [(5-hydroxy-1H- CtaD cytochrome methyltransferase: chaperone: coaD phosphate synthase: a hexanoyl-[acp] SAVERM_RS24865 an N-acyl-(S-diacyl- a peptide carbamoyltransferase: degradation II ATP-NAD kinase: alanyl-γ-D-glutamyl-meso (N-acetylglucosaminyl)muramoyl- acetaldehyde D-glyceraldehyde sn-glycerol methionine an oxidized precorrin-6A synthase/ (5-phospho-D- cob(I)inamide [+ 2 isozymes] adenosylcobinamide- methanesulfonate 5-methoxy-6- γ β (Enterococcus faecium) gly a peptidoglycan pyruvate ethanolamine indol-3-yl)ethyl]- RS33385 cobA dnaK SAVERM_RS11760 oxidase a hexanoyl-[acp] [+ 14 isozymes] sn-glyceryl)-L- glutathioselenol L-citrulline SAVERM_RS12140 -2,6-diaminopimeloyl- L-alanyl- -D-isoglutaminyl-N-( - 3-phosphate 3-phosphate O c-type reductase: 3'-dephospho- dihydrofolate ribosylamino) GDP a long-chain octaheme sulfite monooxygenase: argF methylbenzimidazole nicotinate with D,D cross- D-ala a proteinogenic L-glutamate-5- L-glutamine 2 cobalt- a [chaperone-ATP]- cob(I)yrinic acid 1-deoxy-D- ThiO: thiO a thiocarboxylated- folate transformations III (E. coli) beta-ketoacyl- cysteinyl-[lipoprotein] glyphosate Degradation/ D-alanyl-D-alanine D-asparatyl)-L-lysyl-D-alanine cytochrome SAVERM_RS08490 CoA synthase: pyrimidin- ribazoletransferase: beta-ketoacyl- fatty acyl-CoA reductase: SAVERM_RS06500 [+ 2 isozymes] ribotide phosphate link (S. aureus) amino acid semialdehyde precorrin-5A [co-chaperone]- a,c-diamide xylulose 5- [ThiS sulfur- ACP synthase phosphate acquisition Utilization/ RS08770 dephospho- SAVERM_RS28150 4(3H)-one adenosyltransferase: 2-iminoacetate SAVERM_RS31050 ACP synthase SAVERM_RS11175 Assimilation - Other precorrin-6B [scaffold protein- phosphate carrier protein] II: fabF sulfite CoA kinase: SAVERM_RS14935 a tetrahydrofolate II: fabF glycine (2Fe-2S)] complex 7,8-dihydrofolate α α [+ 2 isozymes] hydrogen sulfide long chain acrylonitrile a ring-opened 7- a mature peptidoglycan a carboxy- β DNA combined a [lipoyl-carrier an unstable SAVERM_RS32090 AIR Co -[ -(5- hydrogen selenide a phosphate oxidase 3'-dephospho- a [protein]- methyl -D-glucoside a ribonucleoside 5-dehydro-4- a mycothiol an L-cysteinyl- RS33200 precorrin-6y C5,15- monoglutamate cob(I)yrinic acid thiazole synthase: [+ 2 isozymes] periplasmic disulfide bond formation polyphosphate degradation I methylguanine glutathione diphosphate H O FAD carbamoyl 6 RecA filament- methylbenzimidazolyl)]- monoester (meso-diaminopimelate CoA hypoglycin A adenylated- cys 2 L-threonine L-ornithine 6-phosphate deoxy-D-glucarate with exogenous glu ala S-conjugate a protein protein]-N -[(R) Pro cobalt- SSQ1 methionine a 3-oxooctanoyl-[acp] bifunctional RNase ThiO: thiO ATP phosphate diphosphate [tRNA ] methyltransferase coenzyme A 5-amino-6-(5- a,c-diamide phosphomethylpyrimidine SAVERM_RS31385 pyridoxal 5'-phosphate biosynthesis I dihydrofolate Coβ-adenosylcobamide in DNA containing) [ThiS sulfur- vitamin B12- 5-dehydro-4- DNA to form a alpha-lytic protease -dihydrolipoyl]- DNA complexDNA precorrin-5B chaperone synthase: metH a 3-oxooctanoyl-[acp] a [DsbB protein] a [DsbA protein] two reduced H/acid phosphatase: (decarboxylating) phospho-D- adenosyltransferase: synthase ThiC: thiC reductase: 5'-phosphate an electron- acrylonitrile carrier protein] dependent deoxyglucarate recombinational prodomain- L-lysine dihydrolipoyl repair RS16330 subunit CbiE: cbiE ATPase: dnaK ribosylamino)uracil D-ribulose cobO 2-[(2R,5Z)- methionine synthase: 3-oxoacyl-[acyl- with reduced L- carrying a cysteine residues SAVERM_RS30290 (aminomethyl) FAD:protein FMN 6-phospho-beta- endonuclease mycothiol D-erythrose SAVERM_RS16795 3-oxoacyl-[acyl- transfer quinone glyoxylate bifunctional DNA- gamma- RdgB/HAM1 family ornithine ribonucleotide dehydratase: junction glutamate-- containing protein: dehydrogenase: Cys- protein 5-phosphate HMP-P 2-carboxy-4- SAVERM_RS14320 carrier-protein] cysteine residues disulfide bond in a protein acid phosphatase: phosphonate lytic transglycosylase transferase: glucosidase: VII domain- conjugate RS32995 a 7,8-dihydrofolate 4-phosphate carrier-protein] formamidopyrimidine triphosphoribosyl- glutamyltransferase: non-canonical carbamoyltransferase: reductase: SAVERM_RS28795 cysteine ligase: SAVERM_RS33680 lpdA tRNA(Pro) RecO: precorrin-7 a [chaperone- bifunctional 3,4- adenosylcobinamide methylthiazol-5(2H reductase: fabG SAVERM_RS30775 domain-containing cysteine SAVERM_RS34755 SAVERM_RS27775 containing protein: amidase an [2Fe-2S] serine α α reductase: fabG acrylamide glycosylase/ dephospho- SAVERM_RS10215 purine NTP SAVERM_RS18795 SAVERM_RS12835 5-dehydro-4- SAVERM_RS35920 dihydrolipoyl deacylase: recO cobalt- ADP]-[disordered- dihydrofolate dihydroxy-2-butanone- bifunctional )-ylidene]ethyl Co -[ -(5- dipyrromethane 3-oxoacyl-[acyl- phosphate protein: desulfurase FAD:protein FMN 6-phospho-beta- resolution ofSAVERM_RS40655 Mca: mca alpha-lytic protease a stabilized precorrin-6y C5,15- cluster protein 2-methyladeninyl adenosylcobamide 5-amino-6-(5- bifunctional hydroxymethyltransferase: DNA-(apurinic CoA synthase: pyrophosphatase: deoxyglucarate dehydrogenase: ybaK precorrin-6A form scaffold reductase: 4-phosphate hydroxymethylpyrimidine phosphate a 7,8-dihydrofolate a 5-methyltetrahydrofolate methylbenzimidazolyl)]- cofactor biosynthesis 3-oxoacyl-[acyl- carrier-protein] amidase domain- SAVERM_RS30135 gamma- DndA: dndA transferase: ornithine glucosidase: ribonucleoside- recombinational[+ 5 isozymes] [+ 3 isozymes] prodomain- RecA filament- methyltransferase biosynthesis from adenosylcobinamide-GDP phospho-D- adenosylcobinamide SAVERM_RS14445 glycine cleavage system β or apyrimidinic SAVERM_RS21890 rdgB dehydratase: a [lipoyl-carrierlpdA cobalt-precorrin- protein] complex SAVERM_RS16795 synthase/GTP kinase/ 4-phospho- Co -adenosylcobamide an apo- carrier-protein] reductase: fabG containing protein: [+ 5 isozymes] glutamyltransferase: ggt [+ 2 isozymes] SAVERM_RS11500 carbamoyltransferase: SAVERM_RS09260 diphosphate junction containing protein: DNA complex RS33380 (decarboxylating) ribitylamino)uracil kinase/ [+ 2 isozymes] aminomethyltransferase site) lyase: mutM [+ 2 isozymes] SAVERM_RS32710 protein]-N 6 -[(R 6A reductase: non- cyclohydrolase II: phosphomethylpyrimidine D-erythronate [hydroxymethylbilane reductase: fabG SAVERM_RS32145 argF reductase: formation of two γ-L-glutamyl- GlcN-Ins a mercapturate SAVERM_RS05495 RS16040 subunit CbiE: cbiE 2-methyladenine bifunctional 5,10- a (3R)-3- 2'-(5''-triphospho- 2,5- )-lipoyl]-L-lysine Pro SAVERM_RS08490 chaperonin a tetrahydrofolate adenosylcobinamide- kinase: thiD GcvT: gcvT a (6S)-5-formyltetrahydrofolate a mature peptidoglycan a mature peptidoglycan a thiocarboxylated- SAVERM_RS15715 intact strands cys a tRNA SAVERM_RS35475 2-(2-carboxy-4- methylenetetrahydrofolate synthase]-L-cysteine a (3R)-3- hydroxyoctanoyl-[acp] [+ 4 isozymes] α-D-ribosyl)-3'- β-D-glucose dioxopentanoate D-alanine a peptide cobalt- molecular phosphate a [DNA]- 2,6-diamino-4- with (L-alanyl-γ-D- strand (non- adenine hypoglycin B L-cysteinylglycine ala [ThiS sulfur- a [protein]-FMN- SAVERM_RS15720 precorrin-8x nicotinate-nucleotide-- 1-deoxy-L- methylthiazol-5- dehydrogenase/5,10-5-formyltetrahydrofolate hydroxyoctanoyl-[acp] a 5'-phospho- AMP + MeOH a 2'- chaperone guanylyltransferase: HMP-PP a [hydroxymethylbilane 3-hydroxyacyl- fatty acid elongation -- saturated nucleotide- hydroxy-5-(N-methyl) 4-oxo-2-pentenal dephospho-CoA phosphate H AMP L-threonine 6-phosphate precorrin-6B dimethylbenzimidazole glycero-tetrulose yl)ethyl phosphate D-glyceraldehyde methenyltetrahydrofolatecyclo-ligase: Carbohydrate Degradation acrylate [DNA] glutamyl-meso-2,6- reducing terminus) carrier protein] L-citrulline deoxyribonucleoside ATPase: dnaK ARP SAVERM_RS31080 (3R)-3-hydroxy-2-oxo- pyruvate synthase] ES 3-hydroxyacyl- ACP dehydratase: 3'-phosphate formamidopyrimidine cobalt-precorrin-6B (C precorrin-8X phosphoribosyltransferase: 4-phosphate 3-phosphate methylenetetrahydrofolate 2 diaminopimeloyl-D- 5'-diphosphate an [Fe-S cluster 4 phosphooxybutanoate cyclohydrolase: SAVERM_RS18970 intermediate ACP dehydratase: SAVERM_RS18860 RS33285 RS26125 15 )-methyltransferase methylmutase: cobT adenosyl-cobinamide thiamine phosphate reductase [NAD(P)H]: metF SAVERM_RS03205 an acetoacetyl-[acp] D-galactose degradation I (Leloir pathway) alanine) tetrapeptide biosynthesis adenosylcobalamin biosynthesis phosphoserine hydroxymethylbilane SAVERM_RS18860 L-rhamnose degradation I [decarboxylating]: SAVERM_RS32940 nicotinate-nucleotide-- 6,7-dimethyl-8- phosphate synthase: 1-deoxy-D-xylulose-5- a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate 2-deoxy-D-ribose degradation II glycogen degradation II chitobiose degradation chaperone]-ATP from adenosylcobinamide-GDP I transaminase: synthase: hemC a (2E)-oct-2-enoyl-[acp] SAVERM_RS32950 dimethylbenzimidazole ribityllumazine SAVERM_RS31415 phosphate synthase: β α a 7,8-dihydro- (S)-2-oxo-4- an N-terminal- hydrogenobyrinate bifunctional serC hydroxymethylbilane a (2E)-oct-2-enoyl-[acp] -D-galactopyranose 2-deoxy-β-D- -L- a peptidoglycan dimer (meso 3-phospho- α L-alanyl-γ-D-glutamyl-L- 2-deoxy-D-ribose UDP-N-acetyl- a D-aspartyl- 5-dehydro- a [protein]-L- phosphoribosyltransferase: synthase: SAVERM_RS08720 bifunctional 5,10- DsbA family a glycogen N,N'-diacetylchitobiose 8-oxoguanine a 5-L-glutamyl- ADP- -D-glucose glu a (6S)-5- uroporphyrinogen-III hydroxy-4-carboxy- H O a pectin L-methionyl-L- a protein a cytidine 34 lys adenosylcobinamide acyl-CoA/acyl-ACP ribopyranose rhamnopyranose an amino acid -diaminopimelate containing) lysyl-D-alanyl-D-alanine 5-phosphate α-D-muramoyl- D-glt 2 asp 2-deoxy-D- methionine cobalt-precorrin-7 5,6-dimethylbenzimidazole 4-phosphooxy- methylenetetrahydrofolate synthase: hemC 6'-phosphate [peptide] D-glycerate GTP [tRNA ] Ile2 hydrogenobyrinate cobT SAVERM_RS35480 thiamine a [hydroxymethylbilane enoyl-ACP dehydrogenase: oxidoreductase: galactose mutarotase: in DNA formyltetrahydrofolate uroporphyrinogen-III 5-ureidoimidazoline gluconate seryl-[protein] in tRNA peptide- RS32515 kinase/ L-threonine 1-deoxy-D-xylulose-5- dehydrogenase/5,10- L-rhamnose L-alanine 2-oxo-4-hydroxy- 5-dehydro-2- ATP-dependent RS12680 a,c-diamide synthase: phosphate synthase] ES reductase SAVERM_RS22490 SAVERM_RS32875 SAVERM_RS29735 C-methyltransferase: methionine bifunctional cobalt- nicotinate-nucleotide-- adenosylcobinamide- phosphate synthase: 3 a 3-oxoacyl-[acp] mutarotase: D-alanyl-D-alanine deoxygluconokinase: pectinesterase: Clp protease: SAVERM_RS32970 biotin biosynthesis from 6,7-dimethyl-8-(1- methenyltetrahydrofolate intermediate a [DsbB protein] a [DsbA protein] [+ 2 isozymes] N-monoacetylchitobiose glucosyl-3- D-alanyl-D-alanine deoxyribose- cobA 4-carboxy-5- (S)-S-oxide precorrin-7 (C(5))- 2-methyladenine dimethylbenzimidazole phosphate thiamine- SAVERM_RS11760 FabI: fabI [+ 9 isozymes] an electron- an intra- SAVERM_RS37410 bifunctional DNA- gamma- carboxypeptidase/ bifunctional UDP-N- D-tyrosyl-tRNA(Tyr) iolC SAVERM_RS32790 type I methionyl SAVERM_RS28125 tRNA 8-amino-7-oxononanoate I D-ribityl)lumazine cyclohydrolase: hydroxymethylbilane carrying a with reduced L- 2-deoxy-ribono- 6'-phosphate phosphoglycerate carboxypeptidase/ phosphate aldolase: ureidoimidazoline GTPase reductase methyltransferase/ hydrogenobyrinate adenosylcobinamide- ribotide phosphate phosphoribosyltransferase: guanylyltransferase: phosphate kinase: [+ 2 isozymes] transfer quinol protein disulfide α-D-galactopyranose an α-limit dextrin formamidopyrimidine glutamyltransferase: D-alanyl-D-alanine- folylpolyglutamate acetylmuramoyl- bifunctional deacylase: aminopeptidase: SAVERM_RS28130 lysidine(34) 3-amino-1- 1-deoxy-D- molybdopterin biosynthesis SAVERM_RS03205 synthase: hemC an octanoyl-[acp] disulfide bond cysteine residues 1,5-lactone L-rhamnose 6-phospho-beta- synthase: D-alanyl-D-alanine- SAVERM_RS27560 decarboxylase: ObgE: obgE 5-dehydro-2- pectinesterase: MsrA: msrA cobalt-precorrin- a,c-diamide (8S)-8-amino-7- GDP cobT riboflavin synthase: SAVERM_RS31080 SAVERM_RS13930 glycosylase/ SAVERM_RS10215 endopeptidase: dacB synthase/ L-alanine--D- uroporphyrinogen-III SAVERM_RS20755 map clpX synthetase a protein-L- RS08270 hydroxyacetone xylulose 5- bifunctional hydroxymethylbilane an octanoyl-[acp] 3-oxoacyl-[acyl- mutarotase: 4-alpha- glucosidase: SAVERM_RS20305 endopeptidase: dacB deoxyribose- SAVERM_RS17560 [+ 6 isozymes] deoxygluconokinase: SAVERM_RS32795 6B (C(15))- putative oxononanoate nicotinate-nucleotide-- SAVERM_RS35465 galactokinase: DNA-(apurinic gamma- dihydrofolate glutamate ligase: C-methyltransferase/ [+ 3 isozymes] [+ 2 isozymes] TilS: tilS methionine- adenosylmethionine- bis(guanylyl molybdopterin) adenosylcobinamide- thiamine 1-phosphate phosphate methylenetetrahydrofolate synthase: hemC carrier-protein] SAVERM_RS38085 glucanotransferase: SAVERM_RS27775 penicillin-binding penicillin-binding phosphate 2-oxo-4-hydroxy- 5-dehydro- iolC RS33095 methyltransferase: cobaltochelatase: adenosylcobinamide- dimethylbenzimidazole molybdenum cofactor biosynthesis galK β or apyrimidinic glutamyltransferase: ggt synthase: SAVERM_RS31520 uroporphyrinogen- (S)-S-oxide -8-amino-7- cofactor sulfurylation GDP diphosphate a [hydroxymethylbilane beta-ketoacyl- reductase: fabG -L- protein 2: mrdA α 4-carboxy-5- + 2-deoxy-D- a peptide GDP riboflavin ATP dehydrogenase/ malQ 6-phospho-beta- 2-O-( -D- protein 2: mrdA aldolase: phosphate H asp a pectate SAVERM_RS32950 SAVERM_RS32980 phosphoribosyltransferase: 6 37 NADPH repair (prokaryotes) 2-deoxy- site) lyase: mutM SAVERM_RS28150 III synthase: tRNA D-aspartate MeOH 34 oxononanoate GTP methenyltetrahydrofolate synthase] ES ACP synthase 3-oxoacyl-[acyl- N -L-threonylcarbamoyladenosine α-D-galactose rhamnopyranose ADP glucopyranosyl) deoC ureidoimidazoline GDP gluconate 6- an N-terminal a lysidine ribazoletransferase: cobT 4 3-oxoacyl-ACP α D-ribonate a debranched glucosidase: SAVERM_RS24485 cobaltochelatase transaminase: bifunctional molybdate intermediate -modified tRNA biosynthesis UDP- -D-glucose L-rhamnose an α-(5-L- a peptidoglycan with UDP-N-acetyl- phosphate met in tRNA Ile2 cobalt-precorrin-8 SAVERM_RS31050 cys cys cyclohydrolase: II: fabF synthase I: carrier-protein] 1-phosphate α-limit dextrin SAVERM_RS09260 -3-phospho- γ decarboxylase: uraD L-seryl-[protein] SecE subunit CobN: cobN α riboflavin kinase/ hydroxymethylbilane Glycolysis a [DNA]- glutamyl)- L-alanyl- -D-glutamyl- α-D-muramoyl-L- precorrin-2 SAVERM_RS36435 adenosylcobinamide- -ribazole pyridoxine GTP 3',8- SAVERM_RS17805 [+ 2 isozymes] SAVERM_RS18875 reductase: fabG NADPH isomerase: a 5'-phospho- 7,8-dihydro- a peptide D,D cross-links (meso- D-ala D-glycerate D-ala a (6S)-5- (S)-(+)-allantoin cob(II)yrinate FAD synthetase: tetrahydrofolate salvage from predicted synthase: hemC N-acetyl-D-glucosamine nucleotide- 4-oxo-2-pentenal amino acid L-lysyl-D-alanine D-glyceraldehyde alanyl-D-glutamate cobalt-precorrin- (7R,8S)-diaminononanoate Coα-[α-(2- GDP 5'-phosphate cysteine desulfurase: molybdopterin 5'-phosphate cysteine desulfurase: cyclase thr rhaI [DNA] 8-oxoguanine diaminopimelate containing) formyltetrahydrofolate acetaldehyde 10 [+ 2 isozymes] 6-phosphate Detoxification 3-phosphate RS26565 8 methylmutase: a,c-diamide methyladenin-9-yl)]-Co SAVERM_RS13280 SAVERM_RS32555 5,10-methenyltetrahydrofolate ABC a carboxy- SAVERM_RS32555 an N -formyltetrahydrofolate hydroxymethylbilane a 3-oxodecanoyl-[acp] a 2,3,4-saturated a (3R)-3-hydroxyacyl- glycolysis III (from glucose) threonylcarbamoyl- 2-deoxy- 3'-phosphate ATP-dependent transporter molybdopterin pyridoxal 5'- MoaA: keto-L-rhamnulose SAVERM_RS32940 β-adenosylcobamide [+ 2 isozymes] adenylated [+ 2 isozymes] synthase: hemC fatty acyl-[acp] [acyl-carrier protein] AMP synthase: 3-dehydro- α-D- dethiobiotin adenosylcobinamide- FMN an [L-cysteine a 5,10- of molybdate: adenylyltransferase: phosphate synthase: moaA a holo- D-glucopyranose reactive oxygen species degradation 5'-phosphate [small subunit of an [L-cysteine (8S)-3',8-cyclo-7,8- 3-oxoacyl-[acyl- 3-hydroxyacyl- D-glucopyranose SAVERM_RS15115 D-ribonate glucopyranose β α a 3-O-acetylated an [RNA]-3'- an N-terminal- a protein-L- HtpX cobyrinate GDP methenyltetrahydrofolate [hydroxymethylbilane (L-threonylcarbamoyl) arsenate a purine base -D-ManNAc-(1->4)- -D- sn-glycerol a CDP- a [protein]- a [protein]- a nucleoside synthetase desulfurase]-S- bifunctional 5,10- modA modB SAVERM_RS22575 SAVERM_RS19760 molybdopterin desulfurase]-S- carrier-protein] ACP dehydratase: CDP-glycerol 2-oxoglutarate a [protein]-L-lysine oxaloacetate Ala oxaloacetate NADH ribazoletransferase: bifunctional dihydroguanosine (R)-NADPHX bifunctional ADP- 1-phosphate detoxification lesion in DNA GlcNAc-PP-undecaprenol diacylglycerol L-aspartate a malonyl-[acp] a palmitoleoyl-[acp] rhamnogalacturonan I L-glutamine RNA asp O-ureido-L- a glycyl-[tRNA ] ribonucleoside- L-saccharopine L-methionyl-L- a protein methionine- BioD: bioD sulfanyl-L-cysteine methylenetetrahydrofolate molybdopterin pyridoxamine synthase] sulfanyl-L-cysteine synthase] reductase: fabG SAVERM_RS18860 ROK family adenylate 3-phosphate ITP triphosphate cobyrinate A,C- SAVERM_RS31050 riboflavin kinase/ bis(guanylyl molybdate 5'-triphosphate dependent NAD(P)H- ROK family superoxide II (glutaredoxin) homoserine 2',3'- citrate synthase/ valyl-[protein] zinc-dependent (R)-S-oxide heme a biosynthesis cysteine desulfurase: dehydrogenase/5,10- adenine dinucleotide 5'-phosphate NAD salvage pathway I (PNC VI cycle) glucokinase: tRNA (adenosine(37)-N6)- L-rhamnulofuranose peptide- diamide synthase: dethiobiotin α α di-trans,poly-cis FAD synthetase: molybdopterin) cyclic pyranopterin 3-oxoacyl-[acyl- alpha-D-glucose glucokinase: cyclophosphateRNA 2',3'-cyclic methylcitrate metalloprotease: RS26555 Co -[ -(2- SAVERM_RS32555 SAVERM_RS10430 threonylcarbamoyltransferase hydrate dehydratase/ superoxide dismutase: arsenate bifunctional DNA- bifunctional glycosyltransferase aspartyl/ rhamnogalacturonan transglutaminase NAD(+) methionine SAVERM_RS32970 -undecaprenyl SAVERM_RS13280 cofactor methenyltetrahydrofolate oxidase: pdxH monophosphate carrier-protein] phosphate-specific SAVERM_RS10430 CDP-diacylglycerol-- beta- DNA-directed D-tyrosyl-tRNA(Tyr) phosphodiesterase: saccharopine synthase: SAVERM_RS15895 methyladenin-7-yl)]-Co adenosylcobalamin + complex: tsaE tsaB tsaD NAD(P)H-hydrate D-glyceroyl-CoA acetoacetate arsenate acetylesterase: argininosuccinate type I methionyl diphosphatase: (R)-S-oxide RS10245 protoheme phosphate biosynthesis [+ 2 isozymes] cyclohydrolase: molybdopterin synthase NAD reductase: fabG ROK family rhamnulokinase: phosphoglucomutase: SAVERM_RS27945 formamidopyrimidine family 2 protein/CDP- asparaginyl beta- domain-containing phosphoenolpyruvate SAVERM_RS12665 cob(II)yrinate biotin synthase β-adenosylcobamide 5'-phosphate a [bis(guanylyl an N 6 -L- epimerase: ROK family reductase ArsC: glycerol-3-phosphate 3- ketoacyl- SAVERM_RS32780 RNA polymerase synthase: argG deacylase: thpR dehydrogenase: aminopeptidase: zinc-dependent nudC reductase protoheme IX (2E,6E)-farnesyl FAD SAVERM_RS03205 molybdotransferase PLP a thiocarboxylated MoaC: moaC glucokinase: SAVERM_RS38050 SAVERM_RS04470 superoxide glycosylase/ glycerol:glycerophosphate hydroxylase domain- protein: carboxykinase (GTP) a,c-diamide BioB: bioB molybdopterin) S-adenosyl-L-methionine salvage II a (3R)-3- threonylcarbamoyladenine 37 SAVERM_RS25620 acetoacetate- glucokinase: SAVERM_RS19405 phosphatidyltransferase: ACP subunit alpha: argininosuccinate SAVERM_RS20755 RNA 2',3'-cyclic SAVERM_RS09435 citrate synthase 2: map metalloprotease: MsrB: msrB farnesyltransferase: diphosphate MoeA: [small subunit of cyclic SAVERM_RS31290 L-rhamnulose dismutase, Ni: sodN DNA-(apurinic glycerophosphotransferase: containing protein: rhamnogalacturonan SAVERM_RS31470 : SAVERM_RS17015 a [protein]-L- isoprenyl transferase: [bis-MGD cofactor cofactor bifunctional NAD+ synthase: NAD(+) hydroxydecanoyl-[acp] in tRNA (S)-NADPHX -CoA ligase: [+ 2 isozymes] SAVERM_RS31290 arsenite pgsA synthase SAVERM_RS02730 synthase: phosphodiesterase: SAVERM_RS19935 [+ 3 isozymes] SAVERM_RS24075 β SAVERM_RS32490 9-mercaptodethiobiotin SAVERM_RS18960 molybdopterin pyranopterin acyl-CoA/acyl-ACP D-glucopyranose 1-phosphate or apyrimidinic SAVERM_RS26270 SAVERM_RS03545 acetylesterase: transglutaminase: (2S,3S)-2- reduced - methionine SAVERM_RS29045 chaperone]- chaperone]-S- methylenetetrahydrofolate SAVERM_RS30660 diphosphatase: a 2,3,4-saturated a trans-2-enoyl- UDP-glucose:α- SAVERM_RS03300 hydrogen peroxide II: fabF [+ 3 isozymes] SAVERM_RS34805 an [RNA]-3'-thpR RS16030 ferroheme o synthase] phosphate NAD+ synthase: SAH 3-hydroxyacyl- dehydrogenase: 6-phosphate UDP-glucose site) lyase: mutM [+ 2 isozymes] SAVERM_RS11075 SAVERM_RS07900 methylcitrate a peptide nicotinamide D- folate polyglutamylation sulfanyl-L-cysteine dehydrogenase/ molybdopterin nudC bifunctional ADP- D-galactose- D-glycerate acetoacetate- CMP 1-(3-sn- a tRNA Ala gly ribunucleoside- allysine glu AMP RS24270 biotin synthase adenosylcobalamin isoprenyl transferase: bis-MGD ACP dehydratase: fatty acyl-[acp] SAVERM_RS31885 [acyl-carrier protein] 4-epimerase a [protein]- phosphoenolpyruvate an N-terminal ribonucleotide methenyltetrahydrofolate molybdotransferase SAVERM_RS30660 adenosylhomocysteinase: glucose-6- dependent NAD(P)H- 1-phosphate -CoA ligase: bifunctional phosphatidyl) 2'-phosphate thioredoxin heme A synthase: BioB: bioB di-trans,octa-cisSAVERM_RS16760 cytosolic NADPH production (yeast) nicotinate adenine SAVERM_RS18860 [+ 9 isozymes] GalE: galE a [DNA]- 3-hydroxy- succinate an (11Z)-3- a rhamnogalacturonan IDP met L-valyl-[protein] cyclohydrolase: MoeA: NMN SAVERM_RS26050 phosphate hydrate dehydratase/ uridylyltransferase: glycerate kinase: SAVERM_RS35800 rhamnulose-1- chitin degradation II (Vibrio) catalase: a 5'-phospho- a modified CMP Gro-P-ManNAc-GlcNAc- -sn-glycerol a protein with an RNA canavaninosuccinate pathway SAVERM_RS32510 -undecaprenyl dinucleotide 4-oxo-2-pentenal oxooctadec- acyl-carrier protein acetate 6 a tetrahydrofolate glutathione SAVERM_RS17805 SAVERM_RS22575 isomerase: pgi Respiration NAD(P)H-hydrate [+ 3 isozymes] SAVERM_RS10105 phosphate aldolase/ SAVERM_RS10660 arsenite nucleotide- [DNA] nucleobase PP-undecaprenol 3-phosphate L-aspartate type I N -(γ-glutamyl)- 10 L-homocysteine α-D-glucopyranose galT biotin diphosphate an N - + a (2E)-dec-2-enoyl-[acp] α 3'-phosphate 11-enoyl-[acp] an oxidized ferroheme i biosynthesis sulfo-bis(guanylyl NAD molybdopterin nicotinate-nucleotide glucose-6- epimerase: UDP- -D-galactose 2-phospho- acetoacetyl-CoA short-chain chitin [+ 3 isozymes] L-lysine crosslink undecaprenyl- formyltetrahydrofolate enoyl-[acyl- 1-phosphate H O hydroxyl radical RS26210 RS15400 serine MoO -molybdopterin adenylyltransferase: 5-methyltetrahydropteroyltriglutamate- 2-oxoisovalerate decarboxylation to isobutanoyl-CoA SAVERM_RS25620 dehydrogenase: 2 thioredoxin bifunctional diphosphate molybdopterin) 2 NAD(+)/NADH kinase: enoyl-ACP biotin-carboxyl carrier carrier-protein] phosphate D-glycerate acetyl-CoA C- phosphoribosylglycinamide cofactor SAVERM_RS38055 D-glucopyranose chitinase: heme A synthase: hydroxymethyltransferase: folylpolyglutamate phosphatase: cys glu cofactor SAVERM_RS25865 SAVERM_RS28275 - homocysteine S- reductase protein assembly reductase isomerase: pgi alpha-D-glucose acyltransferase: O 5-amino-5-(4- a [TusE sulfur D-cellobiose a 2-O-acetylated 3-benzyl-3,6 - a 1-acyl-2- an N-terminal- a peptide with an N-terminal- (3R,5S)-3- formyltransferase: an [apo BCAA NADPH 6-phosphate SAVERM_RS24910 2 a proteinogenic leukotriene-C4 a proteinogenic glutathione a uridine 34 in tRNA an N-modified acetylxylan O-phospho- 3',5'-ADP RNA (2E,6E)-farnesyl SAVERM_RS32510 an N 10 - SAVERM_RS14445 synthase/ SAVERM_RS07060 methyltransferase: metE FabI: fabI FabV: fabV phosphate-specific hydroxybenzyl)- SAM carrier protein]-S 6'-phosphate rhamnogalacturonan I bis(cysteinylglycine) arachidonoyl- L-methionyl-L- an N-terminal cys L-methionyl- hydroxy-1- SAVERM_RS17820 [+ 3 isozymes] a [biotin carboxyl- F6P dehydrogenase SAVERM_RS07380 chitinase: amino acid amino acid aminoacyl-[tRNA] L-homoserine diphosphate thioredoxin- formyltetrahydrofolate [+ 2 isozymes] dihydrofolate NaMN nicotinamide [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] alpha-ketoacid phosphoglucomutase: DHAP (S)-lactaldehyde 6-(D-ribitylimino) -sulfanylcysteine - 6-(hydroxymethyl) sn-glycerol cysteinyl-[protein] L-proline glycyl-[protein] squalene pyrroline-5- undecaprenyl- carrier protein]-L-lysine E2 protein] N 6 [+ 6 isozymes] SAVERM_RS29080 3'(2'),5'-bisphosphate disulfide hydroxyferroheme i synthase: glutamate-- a tetrahydrofolate NADP + bis(guanylyl molybdenum nicotinamidase: dehydrogenase SAVERM_RS04470 -5,6-dihydrouracil -diketopiperazine 3-phosphate CTP carboxylatepyrroline-5- MycP bifunctional diphosphate biotin--[acetyl-CoA- 6-phosphofructokinase: -lipoyl-L-lysine sucrose degradation III (sucrose invertase) 6-phospho-beta- rhamnogalacturonan acetylxylan esterase: nucleotidase CysQ: synthase reductase: a 5,10- SAVERM_RS28150 cysteine ligase: menaquinol-7 biosynthesis cofactor) biosynthesis SAVERM_RS26615 met a decanoyl-[acyl-carrier protein] Tetrapyrrole Biosynthesis subunit beta: acetyl-CoA ribonuclease carboxylate RS12550 folylpolyglutamate phosphatase: carboxylase] ligase: SAVERM_RS31335 [+ 2 isozymes] a chitodextrin gamma- gamma- tRNA 2- glucosidase: acetylesterase: peptidyl-tRNA type I methionyl prolyl SAVERM_RS06980 cystathionine SAVERM_RS02360 type I methionyl HpnC: hpnC trxB methylenetetrahydrofolate SAVERM_RS35920 MoO - dihydrolipoyl SAVERM_RS22560 PH: rph reductase: synthase/ SAVERM_RS36075 menaquinol-11 biosynthesis NADH 2 nicotinate [+ 2 isozymes] sucrose bifunctional FO glutamyltransferase: glutamyltransferase: thiouridine(34) SAVERM_RS32780 membrane phosphatidate hydrolase: aminopeptidase: acetylxylan esterase: gamma-synthase: aminopeptidase: presqualene [+ 3 isozymes] all-trans- glucose-6-phosphate NADP-dependent aldehyde molybdopterin methionine beta-ketoacyl- SAVERM_RS17240 dehydrogenase: D-glucopyranose SAVERM_RS27775 aminopeptidase: pip dihydrofolate bifunctional di-trans,octa-cis molybdopterin phosphoribosyltransferase: tetrapyrrole biosynthesis β alpha-ketoacid biosynthesis SAVERM_RS10215 SAVERM_RS10215 synthase dipeptidase: cytidylyltransferase: SAVERM_RS11620 map SAVERM_RS17110 map proC a tetrahydrofolate heptaprenyl 1,4-dihydroxy- dehydrogenase: isocitrate dehydrogenase cofactor adenosyltransferase: a [biotin carboxyl- -D-fructose 1,6- lpdA 6-phosphate 6-phospho-beta- rhamnogalacturonan SAVERM_RS07750 AMP diphosphate biotin RS27985 biotin synthase: folylpolyglutamate -undecaprenyl all-trans- SAVERM_RS26620 ACP synthase I (from glutamate) siroheme biosynthesis dehydrogenase rhamnogalacturonan type ribose phosphorylation protein CofGH: gamma- gamma- MnmA: mnmA SAVERM_RS25905 SAVERM_RS13660 [+ 2 isozymes] [+ 3 isozymes] [+ 3 isozymes] Hyp ferroheme a menaquinol-10 biosynthesis γ-L-glutamyl- diphosphate 2-naphthoate SAVERM_RS09335 dehydrogenase: (NADP(+)): NAD(+)/NADH kinase: SAVERM_RS35330 carrier protein]-N bisphosphate sucrase ferredoxin: glucosidase: acetylesterase: a nucleoside synthase a reduced phosphate factor 420 undecaprenyl 1,4-dihydroxy- II: fabF 6 dihydrolipoyl subunit beta: I degradation II (bacteria) RNA SAVERM_RS28150 synthase/ SAVERM_RS37060 SAVERM_RS32855 SAVERM_RS25865 molybdenum cofactor nicotinate -biotinyl-L-lysine a chitodextrin SAVERM_RS19605 glutamyltransferase: ggt glutamyltransferase: ggt SAVERM_RS11075 HpnD: hpnD thiol CydD thiol thioredoxin all-trans- L-cysteine polyglutamylation diphosphate 2-naphthoate glucose-6-phosphate [+ 2 isozymes] dehydrogenase: SAVERM_RS22630 SAVERM_RS12675 SAVERM_RS09260 a peptide pro xylan diphosphate 10 dihydrofolate SAM glu uroporphyrinogen-III class II fructose- β 34 3-benzyl-3,6 - a CDP-1-acyl- acetate L-cystathionine squalene 1,4-dihydroxy- an N - dehydrogenase: NAD(+)/NADH kinase: guanylyltransferase: lpdA a rhamnogalacturonan type I -D-ribopyranose a 2-thiouridine a [TusE sulfur carrier an uncharged an N-terminal L- an N-terminal decaprenyl synthase: oxidized glutamate-- bifunctional bisphosphate an [apo BCAA an [apo BCAA dehydrogenase D-ribose 7,8-didemethyl- bis(cysteinyl)- 6- gly 2-arachidonoyl- an N-modified met met RS15185 2-naphthoate formyltetrahydrofolate SAVERM_RS32475 SAVERM_RS05665 SAVERM_RS22570 a 3-oxododecanoyl-[acp] β-D-fructofuranose D-glucopyranose an α-(γ-L-glutamyl) an α-(γ-L-glutamyl) in tRNA protein]-L-cysteine a rhamnogalacturonan tRNA cysteinyl-[protein] glycyl-[protein] diphosphate SAVERM_RS28150 6 rhamnogalacturonase 5'-deoxyadenosine 8-hydroxy-5- leukotriene-D4 L-cysteinylglycine D-glucopyranose (hydroxymethyl) glycerol amino acid cytidylyl molybdenum factor 420-0coenzyme F420-0:L- pyridoxal 5'-phosphate biosynthesis II a [biotin carboxyl- tRNA ligase: uroporphyrinogen-III aldolase: fbaA dehydrogenase E2 protein] N -S-[2- (1,4)-β-D-xylan pyranase: met -L-amino acid -L-amino acid D-glucopyranose acetate type I thr thr NAD phosphorylation demethylmenaquinol-7 6 B precursor: deazariboflavin 6-phosphate -diketopiperazine RS24060 lipoate biosynthesis a 5,10- cofactor sulfurylation glutamate ligase: bis(molybdenum 3-oxoacyl-[acyl- carrier-protein dimer]- an L-glutamyl-SAVERM_RS14035 C-methyltransferase/ E2 protein] N - methylpropanoyl]dihydrolipoyl- degradation ROK family rbsD serine serine and transhydrogenation glutathione NADPH bis(guanylyl tungstenpterin) SAVERM_RS11080 and incorporation I methylenetetrahydrofolate 6 Glu uroporphyrinogen- dihydrolipoyl-L-lysine L-lysine glucokinase: β-D-ribofuranose beta-N- cytidylyl molybdenum demethylmenaquinone SAVERM_RS25985 DMKH2-11 cofactor) aldehydo-D-ribose D-glyceraldehyde gln cofactor biosynthesis carrier-protein] N -biotinyl-L-lysine [tRNA ] triose-phosphate oxidized menaquinol-9 biosynthesis III synthase: a (1->4)-β-D-xylan SAVERM_RS10430 4-deoxy-4,5-unsaturated α- acetylhexosaminidase: guanylyl molybdenum + methyltransferase: molybdenum cofactor reductase: fabG acetyl-CoA a [ribosomal an NDP-α- a peptidoglycan sn-glycero-3- DNA with adenine:7,8- a [protein] N- a [2-oxoglutarate cofactor (trioxo) NAD factor 420-1 demethylmenaquinone 5-phosphate 3-phosphate glutamyl-tRNA isomerase: endo-1,4-beta- D-galactopyranosyluronate- 3-aci- 3-phospho- an organic an unfolded RS23110 an octanoyl-[acp] DMKH2-10 cofactor biosynthesis SAVERM_RS24930 guanylyltransferase: 3-oxoacyl-[acyl- carboxylase SAVERM_RS24485 fructokinase: ROK family N,N'- SAVERM_RS26485 N,N',N''- a sulfurated protein S12] a ferrocytochrome palmitoyl-CoA D-glucose dimer (generic) phospho-N- dihydro-8- an N-acylated- urea-1-carboxylate terminal-formyl- a tRNA precursor cys L-homocysteine acetyl-CoA dehydrogenase N-ethylglycine a metal a metal NAD(+)/NADH kinase: F420-1:γ- methyltransferase: biotin carboxylase: reductase: SAVERM_RS32400D-glyceraldehyde xylanase: [rhamnogalacturonan dGTP nitropropanoate D-glycerate hydroperoxide protein RS10265 lipoyl(octanoyl) GTP SAVERM_RS10430 glucokinase: [sulfur carrier] 89 b D-amino acid 6 cation cation MoO - SAVERM_RS25865 demethylmenaquinol-9 SAVERM_RS22570 pyridoxal 5'- bis(tungstenpterin) carrier-protein] subunit beta: uroporphyrinogen-III DHAP diacetylchitobiose triacetylchitotriose L-aspartate 5 (arachidonoyl) oxoguanine mismatch L-methionine acetyl-CoA E2 protein] N thioredoxin- chaperonin demethylmenaquinone 2 an [MCD cofactor menaquinol-7 glutamyl ligase: SAVERM_RS24930 SAVERM_RS27245 SAVERM_RS24475 3-phosphate glyoxylate cycle SAVERM_RS25710 I oligosaccharide] transferase molybdopterin acyl carrier [+ 3 isozymes] NADP biosynthesis demethylmenaquinone menaquinol-8 biosynthesis bis(guanylyl phosphate cofactor reductase: fabG SAVERM_RS27245 C-methyltransferase: 2-oxo acid SAVERM_RS31290 D-ribofuranose beta-N- ethanolamine carboxylase -dihydrolipoyl- dependent GroEL: groL methyltransferase: chaperone]-MCD SAVERM_RS25985 (S)-4-amino-5- type I endo-1,4-beta- nitronate glucosyl-3- lytic transglycosylase allophanate dihydrolipoyl glycine a [lipoyl-carrier protein]LipB: lipB cofactor molybdenum cofactor protein activation NADP + menaquinol-11 methyltransferase: molybdopterin) synthase: [+ 2 isozymes] cobA dehydrogenase D-glucopyranose acetylhexosaminidase: acyl-CoA desaturase: A/G-specific adenine D-aminoacylase: cystathionine subunit beta: L-lysine thiol SAVERM_RS24930 cysteine desulfurase: oxidized a (3R)-3- oxopentanoate glyceraldehyde- xylanase: ribokinase: 30S ribosomal monooxygenase: phosphoglycerate domain-containing hydrolase subunit 1: peptide deformylase: ribonuclease D: dehydrogenase: oxidase chaperonin a metal a metal 6 SAVERM_RS24930 cofactor molybdenum cofactor a [carboxyl-carrier precorrin-1 subunit E2: succinate acetyl-CoA 6-phosphate SAVERM_RS26485 deoxyguanosinetriphosphate SAVERM_RS27245 peroxidase: RS11520 N -octanoyl-L-lysine guanylyltransferase: NAD + demethylmenaquinol-8 pdxS pdxT hydroxydodecanoyl-[acp] protein S12 SAVERM_RS08430 protein: glycerophosphodiester glycosylase: SAVERM_RS16990 SAVERM_RS37735 beta-synthase: ThiO: thiO GroEL: groL RS36185 an apo acyl- SAVERM_RS32555 Re/Si-specific NAD(P) factor 420-2 menaquinol-9 guanylyltransferase: 6 glutamate-1- 3-phosphate SAVERM_RS22565 β SAVERM_RS11020 2-O-(4-deoxy-β-L-threo- SAVERM_RS27450 SAVERM_RS28750 synthase: SAVERM_RS35640 SAVERM_RS11695 lpdA cation cation menaquinol-10 guanylyl SAVERM_RS22570 demethylmenaquinone protein dimer]-N - a (1->4)- -D-xylan glucose-6- N-acetyl-D- methylthiotransferase acyl-CoA desaturase: triphosphohydrolase: SAVERM_RS30135 phosphodiesterase: SAVERM_RS24295 D-aminoacylase: [+ 2 isozymes] SAVERM_RS18135 [+ 2 isozymes] bcp lipoyl carrier protein [+ 2 isozymes] (+) transhydrogenase NAD(+)/NADH kinase: SAVERM_RS22570 3-hydroxyacyl- semialdehyde bifunctional dehydrogenase: glyoxylate hex-4-enopyranuronosyl) D-ribofuranose [+ 3 isozymes] SAVERM_RS20305 allophanate dihydrolipoyl a protein molybdenum holo-ACP synthase: methyltransferase: carboxybiotinyl-L-lysine 2-oxo acid oligosaccharide D-xylose phosphate glucosamine RimO: rimO SAVERM_RS12015 SAVERM_RS29270 SAVERM_RS21845 SAVERM_RS19630 malonyl-CoA an alcohol synthase: lipA a [cytidylyl molybdenum subunit beta: pntB SAVERM_RS25865 PLP ACP dehydratase: 2,1- uroporphyrinogen-III gap malate synthase A: -α-L-rhamnopyranose 5-phosphate [+ 5 isozymes] hydrolase: atzF dehydrogenase: cofactor SAVERM_RS25615 SAVERM_RS24930 dehydrogenase beta-xylosidase: degradation I isomerase: pgi a [2-oxoglutarate ethylamine glyoxylate a [lipoyl-carrier cofactor chaperone]- [+ 3 isozymes] bis(guanylyl SAVERM_RS18860 aminomutase: C-methyltransferase/ SAVERM_RS10530 [unspecified 2-O-(α-D- [+ 7 isozymes] an apurinic site an N-terminal L- a nucleoside 5'- lpdA a metal a metal a holo acyl- + type I subunit E2: SAVERM_RS28850 fructose degradation formate a tRNA dehydrogenase RS36210 protein]-N 6 -[(R)- cytidylyl molybdenum NADPH NADP menaquinol-8 hemL uroporphyrinogen- isocitrate lyase:malate aceA synthase A: D-xylose glucose-6- a [ribosomal 3-oxopropanoate nitrite degradation a nucleoside GlcNAc-1,6- adenine within DNA methionyl-[protein] monophosphate L-cystathionine cation cation RS21975 carrier protein tungstenpterin) cofactor glyceraldehyde- SAVERM_RS22635 [+ 2 isozymes] 5'-deoxyadenosine an unsulfurated palmitoleoyl-CoA a ferricytochrome triphosphate glucopyranosyl) a lipid II a carboxylate E2 protein] N 6 dihydrolipoyl]-L-lysine cofactor (sulfo-dioxo) a (2E)-dodec-2-enoyl-[acp] III synthase: SAVERM_RS10750 xylose phosphate β met protein S12]-3- 2'-deoxyguanosine products] diphosphate anhydro-MurNAc- a D-amino acid ammonium CO 3-phosphate melibiose degradation -D-fructofuranose [sulfur carrier] b -3-phospho- sn-glycerol 2 -lipoyl-L-lysine 5-aminolevulinate β isomerase: pgi methylsulfanyl- 5 anandamide fatty acid biosynthesis SAVERM_RS24485 dehydrogenase: -D-xylopyranose isomerase: 4-deoxy-L-threo-hex- 1-phosphate D-glycerate pentapeptide 3-phosphate enoyl-ACP L-rhamnopyranose 1-phosphofructokinase: L-aspartate 89 a metal a metal initiation (type II) uroporphyrinogen-III gap xylA 4-enopyranuronate RS10500 reductase porphobilinogen F6P melibiose pfkB cation cation C-methyltransferase: D-xylulose β-D-fructose 1,6- RS15825 Amino Acid Biosynthesis FabI: fabI synthase: hemB D-threo-isocitrate (S)-malate 6 acetyl-CoA cobA 13-DPG bisphosphate a [DNA]-3'- a 5'-phospho- a [protein]- an O - 3D-(3,5/4)- an N-acetyl-α- a 2'- N-acetyl-D- a CDP- D-sedoheptulose 6-O-trans- a glucosylated xylulokinase: cob(II)inamide NAD + a ferrocytochrome stearoyl-CoA a peptidoglycan a peptide with a a RNA-DNA hybrid 4-hydroxy- [+ 2 isozymes] acetyl-CoA porphobilinogen alpha-galactosidase: hydroxyl [DNA] L-cysteine methylguanine trihydroxycyclohexane- D-glucosaminide deoxyribonucleoside [DNA] galactosamine diacylglycerol 1-phosphate methoxy-mycolyl- glycogenin precorrin-2 xylB ATP b leader sequence L-threonine GTP ATP 1,4-alpha- a metal a metal L-histidine biosynthesis carboxylase phosphoglycerate SAVERM_RS37320 5 in DNA 1,2-dione 5'-triphosphate 6-phosphate biotin trehalose 6- RS38320 L-lysine biosynthesis I L-arginine biosynthesis I (via L-ornithine) L-arginine biosynthesis II (acetyl cycle) L-tryptophan biosynthesis uracil degradation L-ornithine L-arginine L-homoserine L-cysteine biosynthesis I a dodecanoyl-[acp] D-xylulose 3D-(3,5/4)- glucan cation cation L-glutamate Polyprenyl Biosynthesis subunit beta: hydroxymethylbilane kinase: aconitate hydratase malate dehydrogenase: [+ 3 isozymes] adenylate/guanylate phosphate I (reductive) biosynthesis II degradation I biosynthesis precorrin-2 5-phosphate ATP-dependent lysozyme: trihydroxycyclohexane- alpha-N- bifunctional RNase CDP-diacylglycerol class II fructose- trehalose- branching biosynthesis II SAVERM_RS27245 synthase: hemC SAVERM_RS32395 AcnA: acnA SAVERM_RS17775 cob(I)yrinic acid a,c-diamide acyl-CoA desaturase: methylated-DNA-- signal group II N-acetylglucosamine- low specificity L- cyclase domain- RS07455 PRPP (arginase pathway) dehydrogenase: Alcohol Degradation DNA ligase: SAVERM_RS33010 1,2-dione acylhydrolase acetylglucosaminidase: H/acid phosphatase: diphosphatase: bisphosphate phosphatase: enzyme: asp N-acetylglutamyl- gln uracil ser [+ 2 isozymes] hydroxymethylbilane D-galactopyranose D-glucopyranose adenosyltransferase: cobO SAVERM_RS08430 [protein]-cysteine S- peptidase I: lepB intron reverse 6-phosphate threonine aldolase: containing protein: biotin--[acetyl-CoA- glu amino-acid N- chorismate 2-oxoglutarate trans, trans-farnesyl beta-ketoacyl- cobA 3-phospho-D-glycerate SAVERM_RS36655 lysozyme: (decyclizing): iolD SAVERM_RS30860 SAVERM_RS30290 SAVERM_RS39520 aldolase: fbaA trehalose-otsB glgB a metal a metal ATP 2-oxoglutarate phosphate asp geranyl diphosphate malonyl-CoA synthase: hemC methyltransferase: transcriptase/ deacetylase: nagA SAVERM_RS07905 SAVERM_RS17235 carboxylase] ligase: RS14385 aspartate kinase: glutamate acetyltransferase: glutamate arg diphosphate ACP synthase cob(I)yrinic acid a,c-diamide [+ 3 isozymes] acyl-CoA desaturase: SAVERM_RS15415 3D-(3,5/4)- alpha-N- [+ 3 isozymes] [+ 2 isozymes] trans-methoxy- cation cation phosphoribosyltransferase: amino-acid N- aspartate kinase: biosynthesis sirohydrochlorin glycerol and glycerophosphodiester degradation glycerol degradation V SAVERM_RS32260 maturase: ltrA cyclic-GMP SAVERM_RS17240 a glycogen SAVERM_RS23555 dehydrogenase: SAVERM_RS24230 dehydrogenase: biosynthesis II: fabF preuroporphyrinogen phosphoglyceromutase: cis-aconitate oxaloacetate ethanol degradation II adenosyltransferase: SAVERM_RS12015 trihydroxycyclohexane- acetylglucosaminidase: a 1,2-diacyl- mono-mycolate SAVERM_RS35490 acetyltransferase: anthranilate 5,6-dihydrouracil SAVERM_RS23555 laurate ACP S- [+ 2 isozymes] CMP D-erythrose SAVERM_RS08670 SAVERM_RS08670 [+ 2 isozymes] sirohydrochlorin SAVERM_RS20530 SAVERM_RS14935 N-acetyl-D- a N-acetylmuramoyl- 1,2-dione acylhydrolase SAVERM_RS10600 D-galactosamine sn-glycerol DHAP RS14405 1-(5-phospho- L-aspartyl-4-phosphate SAVERM_RS24230 bifunctional synthase component L-aspartyl- IPP IPP malonyltransferase: a glycerophosphodiester glycerol acetate glycolaldehyde N-acetyl-gamma- glu bifunctional chelatase: aconitate hydratase glycerol [DNA] NMN glucosamine pentapeptide- (decyclizing): iolD a leader sequence a peptide DNA a nucleoside 5'- 6-phosphate 3-phosphate gly biotinyl-5'- a metal a metal β-D-ribosyl)-ATP glu glutamate N- I: SAVERM_RS31770 dihydropyrimidinase: L-ornithine 4-phosphate isopentenyl- long-chain fatty SAVERM_RS29845 ethanol AMP a ferricytochrome oleoyl-CoA a [protein]-S- [DNA] RS26045 bifunctional glutamyl-phosphate O-acetyl-L-serine prenyltransferase: uroporphyrinogen-III SAVERM_RS29265 2-phospho-D-glycerate AcnA: acnA ethanol adenosylcobinamide diphosphoundecaprenol a guanine in DNA 5-deoxy-D- N-acetyl-D- monophosphate adenylate cation cation aspartate- acetyltransferase/ hydA hydrogen sulfide diphosphate acid--CoA ligase: citrate synthase/ b methyl-L-cysteine a non glycosylated phosphoribosyl-ATP glutamate N- reductase: SAVERM_RS30195 a 3-oxotetradecanoyl-[acp] triphosphate 5 glucuronate semialdehyde amino-acid glutamate 5-kinase: ornithine- aspartate- Delta- SAVERM_RS21755 a malonyl-[acp] C-methyltransferase/ [+ 2 isozymes] methylcitrate synthase: glycerophosphoryl dehydrogenase: glucosamine sugar acceptor diphosphatase: acetyltransferase/ acetylglutamate SAVERM_RS34730 anthranilate PRPP geranyl phosphopyruvate dehydrogenase: acetyltransferase 3-ureidopropanoate SAVERM_RS28245 -oxo-acid semialdehyde isomerase: idi [+ 14 isozymes] uroporphyrinogen- SAVERM_RS12665 diester SAVERM_RS35715 dihydroxyacetone SAVERM_RS35485 amino-acid kinase: argB cysteine synthase: diphosphate Amine and Polyamine Biosynthesis 3-oxoacyl-[acyl- siroheme hydratase: eno glycine glycine RS20505 SAVERM_RS23560 ArgJ: argJ transaminase: dehydrogenase: DMAPP ketoacyl-ACP III synthase: phosphodiesterase glycerol acetaldehyde RS26550 γ carrier-protein] citrate synthase: dihydroxyacetone 4 1-(5-phospho-β- acetyltransferase glu gln N-acetyl-L-glutamate β-ureidopropionase: -L-glutamyl SAVERM_RS26650 lauroyl-CoA synthase III: SAVERM_RS24485 (1S,2R)-1- an O - a peptide with betaine betaine N-acetyl-L-glutamate anthranilate rocD SAVERM_RS23560 reductase: fabG phosphoenolpyruvate SAVERM_RS27515 membrane domain- kinase subunit a [protein]- 2-hydroxy-4-oxobutane- DNA containing S-methyl-L- pyridoxamine a DNA containing an L-glutamyl- N-methyl-L- D-sedoheptulose D-ribosyl)-AMP aspartate- ArgJ: argJ 5-semialdehyde SAVERM_RS10280 5-phosphate ectoine biosynthesis SAVERM_RS29840 citrate acetaldehyde cob(II)alamin ala a pimeloyl-[acp] glycyl-glycine glutathione C-(indol-3- methylthymine an N-terminal L-homocysteine oxaloacetate a protein a protein phosphoribosyltransferase: trpD ornithine- aspartate- prenyltransferase: spermidine biosynthesis III putrescine uroporphyrinogen- acetyl-CoA Carboxylate Degradation containing protein: glycerol kinase DhaK: dhaK ATP ser L-cysteine ATP 1,2,4-tricarboxylate a base with lesion methionine 5'-phosphate a mismatch [tRNA Gln ] tryptophan 1,7-bisphosphate semialdehyde glutamine- acetylornithine glutamate-5- 3-oxoacyl-[acyl- [+ 3 isozymes] dehydrogenase: yl)glycerol in DNA a tRNA precursor Xaa-L-proline citrate synthase/ pyridoxal 5'- phosphoribosyl- N-acetyl-L- superpathway of branched chain amino acid biosynthesis -oxo-acid semialdehyde cys SAVERM_RS30195 biosynthesis I cadaverine III synthase: pyruvate SAVERM_RS26110 GlpK: glpK CTP Asp-tRNA(Asn) ATP- snapalysin: dehydrogenase: hydrolyzing transaminase: β carrier-protein] SAVERM_RS17320 methylcitrate fluoride CrcB fluoride AMP glutamate bifunctional -alanine semialdehyde dehydrogenase: biosynthesis SAVERM_RS26415 kinase: pyk [+ 7 isozymes] [+ 2 isozymes] DHAP 3-phosphate phosphate synthase: /Glu-tRNA(Gln) dependent zinc snpA RS20125 SAVERM_RS27860 carbamoyl- SAVERM_RS34745 N-(5-phosphoribosyl)-anthranilate transaminase: geranyl asp reductase: fabG an acetoacetyl-[acp] glycolate and gamma- methylated-DNA-- 4-carboxy-4-hydroxy- G/U mismatch- synthase: G/U mismatch- class II fructose- cyclohydrolase: glutamate N- dehydrogenase: SAVERM_RS27860 arg SAM pyruvate pyruvate decarboxylation to acetyl CoA I propanoyl CoA degradation I pyruvate fermentation to acetate IV oxalate degradation II acetate cob(I)yrinic acid a,c-diamide 8-amino-7- leucyl homocysteine S- SAVERM_RS19760 amidotransferase: N-methyl-L- metalloprotease snapalysin: pyruvate thr phosphate rocD diphosphate aspartate kinase: arg uroporphyrinogen-III glyoxylate glutamyltransferase: tryptophan [protein]-cysteine S- CCA tRNA 2-oxoadipate specific DNA SAVERM_RS12665 specific DNA bisphosphate hisI L-aspartate 4- acetylglutamate acetyltransferase/ SAVERM_RS28255 a (3R)-3- stearate biosynthesis kinase: pyk pyruvate fermentation adenosyltransferase: oxononanoate aminopeptidase: methyltransferase: pyridoxamine gatB gatA gatC tryptophan FtsH: ftsH snpA β synthase: bifunctional 1-(5- L-glutamate-5- L-aspartate 4- SAVERM_RS23555 lys degradation I SAVERM_RS10215 synthase: trpB methyltransferase: nucleotidyltransferase: aldolase/oxaloacetate glycosylase: glycosylase: an L-glutaminyl- aldolase: fbaA 1-(5-phospho- -D-ribosyl)- semialdehyde kinase: argB acetolactate amino-acid L-glutamate-5- prenyltransferase: hydroxytetradecanoyl-[acp] II (bacteria and plants) a [pyruvate dehydrogenase to acetate II oxalate sn-glycerol 3-phosphate acetate--CoA SAVERM_RS14935 synthase: SAVERM_RS31045 mmuM citrate synthase: 5'-phosphate oxidase: solA fluoride CrcB fluoride threonine carA carB phosphoribosyl)-5-((5- semialdehyde L-aspartyl- lysine pyruvate propanoyl-CoA pyruvate gamma- SAVERM_RS31805 decarboxylase: mug mug Gln a peptide a peptide 5-[(5-phosphoribosylamino) synthase: acetyltransferase semialdehyde glycolate 6 ligase: acs SAVERM_RS36445 SAVERM_RS32260 SAVERM_RS22225 SAVERM_RS27515 oxidase: pdxH [tRNA ] 4-hydroxy- N-acetylglutamyl- phosphoribosylamino) semialdehyde SAVERM_RS30195 decarboxylase 3-hydroxyacyl- E2 protein] N -lipoyl-L-lysine pyruvate acyl-CoA carboxylase: cob(I)yrinic acid a,c-diamide SAVERM_RS08570 1,2- methylideneamino]imidazole- SAVERM_RS09600 ammonia-lyase: ArgJ: argJ homoserine 4-phosphate agmatine glutamyltransferase: ggt [+ 2 isozymes] D-erythrose RS14415 tetrahydrodipicolinate phosphate carbamoyl phosphate L-ornithine methylideneamino)imidazole- L-glutamate ACP dehydratase: a palmitoyl-[acp] pyruvate SAVERM_RS12040 pyruvate adenosyltransferase: cobO D-glyceraldehyde a peptide with dihydroxypropane- PLP DHAP 4-carboxamide SAVERM_RS17090 ornithine- dehydrogenase: (2E,6E)-farnesyl DesA: desA acetyl-CoA a tRNA a proteinogenic a DNA containing a modified an apyrimidinic uracil formaldehyde 4-phosphate synthase: dapA acetolactate 4- carboxamide isomerase/ gamma- aspartate- agmatine dAdoMet cadaverine SAVERM_RS18860 beta-ketoacyl- pyruvate dehydrogenase SAVERM_RS12045 pyruvate 3-phosphate trp an N-terminal met 1,2,3-tricarboxylate trp N-acetyl-gamma- (2Z)-2-aminobut- N-acetyl-L-ornithine -oxo-acid diphosphate agmatinase: oxalyl-CoA (8S)-8-amino-7- γ amino acid an apurinic/ nucleobase site in DNA fluoride CrcB fluoride bifunctional 1-(5- 4-hydroxy- synthase: ilvN phosphoribosylanthranilate semialdehyde SAVERM_RS41635 semialdehyde ACP synthase glyoxylate dehydrogenase: (acetyl- dehydrogenase: acyl-carrier protein -L-glutamyl- a [protein]-S- containing a oxaloacetate pyruvate L-proline glutamyl-phosphate 2-enoate transaminase: speB (S)-methylmalonyl-[+ 2 isozymes] DHAP adenosylcobalamin oxononanoate L-cysteinylglycine a thymine in DNA apyrimidinic site phosphoribosyl)-5-((5- tetrahydrodipicolinate SAVERM_RS14240 isomerase PriA: priA dehydrogenase: dehydrogenase: a (2E)-tetradec-2-enoyl-[acp] II: fabF Fermentation mixed acid fermentation SAVERM_RS10925 transferring), SAVERM_RS10925 oxalyl-CoA triphosphate glycylglycine methyl-L-cysteine 3' CCA end phosphoribosylamino) reductase: rocD L-homoserine polyamine glyoxylate CoA acetyl-CoA formate synthase: dapA pruA SAVERM_RS23560 [+ 2 isozymes] homodimeric acetyl-CoA decarboxylase: RS19045 methylideneamino)imidazole- SAVERM_RS34730 (S)-2-acetolactate 1-(2-carboxyphenylamino)-1- ornithine- aminopropyltransferase: putrescine carboligase: [+ 2 isozymes] methylmalonyl- (2S,4S)-4- enoyl-ACP a 3-oxooctadecanoyl-[acp] phosphoenolpyruvate type: aceE SAVERM_RS09600 Cd 2+ CadA Cd 2+ 4- carboxamide isomerase/ N-acetyl-L- deoxy-D-ribulose 5-phosphate -oxo-acid glu L-cysteine biosynthesis V (mycobacteria) aspartate- SAVERM_RS23345 gcl CoA phosphate phosphate hydroxy-2,3,4,5- ornithine superpathway of L-cysteine reductase [+ 4 isozymes] α glutamate 5- ketol-acid semialdehyde acetyltransferase: pta UDP-N-acetyl- -D-muramoyl- 7,8-didemethyl- 3-(D-glyceryl) 7,8-didemethyl- enolpyruvoyl- α (1E,4S,5E,7R)- α phosphoribosylanthranilate L-isoleucine indole-3-glycerol transaminase: epimerase: mce acetyltransferase: pta formyl-CoA a [protein]- a DNA methyl + a D-tyrosyl- + (S)-1-pyrroline- dTDP- -D-glucose α tetrahydrodipicolinate 2-iminobutanoate carbamoyltransferase: 1 FabI: fabI 3-oxoacyl-[acyl- tartronate di-trans,octa-cis- a (4Z)-hexadec- pimeloyl-CoA NADPH NAD an N -methyl L-threo-3- protoheme ammonium NAD H O -amylose reductoisomerase: biosynthesis (mammalian) dehydrogenase: N -(3- a [pyruvate dehydrogenase a [pyruvate dehydrogenase L-alanyl-γ-D-glutamyl-L- 8-hydroxy-5- -diphospho- 8-hydroxy-5- 2-diphospho- a malonyl-[acp] ala 2 germacra-1(10) L-homocysteine sarcosine isomerase PriA: priA semialdehyde biosynthesis IV phosphate rocD pyruvate kinase: pyk phosphoenolpyruvate semialdehyde superpathway of acetate undecaprenyl phosphate 4-enoyl-[acp] L-cysteine phosphotriester L-amino acid phenylserine [tRNA Tyr ] 5-carboxylate dTDP- 4-hydroxy- SAVERM_RS18795 O-phospho- [+ 2 isozymes] carrier-protein] 6 6 (R)-methylmalonyl- L-glutamate 1,4-alpha- citrate RS33870 citrate acetylornithine ilvC a [CysO sulfur- SAVERM_RS27860 aminopropyl) E2 protein] N - E2 protein] N -S- acetyl phosphate formyl-CoA lysyl-D-alanyl-D-alanine deazariboflavin 5'-guanosine deazariboflavin 5'-guanosine ,5-dien-11-ol 2+ 2+ tetrahydrodipicolinate hydrogencarbonate synthase TrpC: trpC L-serine reductase: fabG pyruvate kinase: pyk carboxylase: ppc 2-hydroxy-3- CoA acetyl phosphate utilization and formation homocysteine S- glucose 4,6- Cd CadA Cd phosphoribulosylformimino- transaminase: (2R)-2,3- ornithine met L-ornithine carrier protein]- agmatine dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine transferase: frc gamma- glucan reductase: carbamoyltransferase: propanoate (1S,2R)-1-C-(indol-3- L-aspartate 4- a myristoyl-[acp] oxopropionate methylmalonyl-CoA methylated-DNA-- Re/Si-specific deferrochelatase/ nitrite methyltransferase: semialdehyde dehydratase: branching AICAR-phosphate SAVERM_RS34745 dihydroxy-3- thiocarboxylate spermidine biosynthesis I 3-oxoacyl-[acyl- acetate kinase: phospho-N- 2-phospho-L- 2-phospho-L- beta-ketoacyl- 8-amino-7- N-methyl-L- low specificity L- D-tyrosyl-tRNA(Tyr) germacradienol/ SAVERM_RS13160 glutamine- argF long-chain fatty yl)glycerol 3-phosphate L-glutamate semialdehyde pyruvate oxaloacetate reductase: mutase subunit beta: acetate kinase: acetate [protein]-cysteine S- NAD(P)(+) peroxidase EfeB: efeB reductase: mmuM glycine oxidase dehydrogenase: rfbB enzyme: methylbutanoate 2-oxobutanoate methionine carrier-protein] SAVERM_RS14690 formate acetate--CoA acetylmuramoyl- lactate transferase: lactate transferase: ACP synthase oxononanoate tryptophan threonine aldolase: deacylase: geosmin synthase: RS18625 hydrolyzing N-acetyl-L- acid--CoA ligase: beta-ketoacyl- SAVERM_RS14690 transhydrogenase nirD nirB ThiO: thiO dTDP-4-dehydro- 2+ 2+ imidazole (S)-2,3,4,5- dihydroxy-acid tryptophan adenosyltransferase: biosynthesis III adenylyltransferase/ diaminobutyrate- reductase: fabG SAVERM_RS10655 SAVERM_RS10725 ligase: acs pentapeptide- methyltransferase: [+ 2 isozymes] pruA glgB Co RS30150 Co carbamoyl- ornithine SAVERM_RS21755 ACP synthase malate acetate kinase: SAVERM_RS25990 SAVERM_RS25990 II: fabF synthase: subunit alpha: oxidase: solA SAVERM_RS07905 SAVERM_RS20755 SAVERM_RS11355 met 6-deoxy-α-D- glycerol tetrahydrodipicolinate dehydratase: acetolactate synthase: trpB SAVERM_RS35330 sulfurtransferase -2-oxoglutarate spermidine SAM [+ 3 isozymes] acetate transferase: SAVERM_RS32260 amylopectin phosphate [+ 14 isozymes] 2-oxoglutarate II: fabF a (3R)-3- dehydrogenase: D-glycerate acetate SAVERM_RS14690 SAVERM_RS36445 SAVERM_RS02520 glu glucopyranose phosphate 2,3,4,5- ilvD synthase: SAVERM_RS31805 MoeZ: moeZ transaminase: ectB pyruvate SAVERM_RS31515 [+ 2 isozymes] synthase: propanoyl-CoA hydroxyoctadecanoyl-[acp] SAVERM_RS17775 2+ nitrite SAVERM_RS09600 SAM glutamate synthase L-2,4- [+ 2 isozymes] dehydrogenase: succinyl-CoA oxidized 3PG- dehydro a (6Z)-3-oxooctadec- Fe protoporphyrin IX glyoxylate methylamine synthase: tetrahydropyridine- carA carB 3-methyl-2- ser a [CysO sulfur- glycerate kinase: D-gluconate acetyl phosphate acetyl-CoA acyl-carrier protein formaldehyde an L-amino acid benzaldehyde gly D-tyrosine a tRNA Tyr acetone (-)-geosmin Co 2+ CbiQ Co 2+ indole large subunit: gltB a [CysO sulfur- diaminobutanoate 3-hydroxyacyl- acetyl-CoASAVERM_RS10925 factor 420-0 GMP factor 420-0 GMP 6-enoyl-[acp] (8S)-8-amino-7- RS15985 hisH hisF 2,6-dicarboxylate N- oxobutanoate acetolactate 2-oxoacid:ferredoxin carrier protein]- (R)-lactate (S)-malate SAVERM_RS10105 degradation a [protein]-S- coenzyme A + L-citrulline glutamate carrier protein]- a 3-oxohexadecanoyl-[acp] ACP dehydratase: formate acetyl-CoA undecaprenyl-diphospho-N- UMP [DNA] oxononanoate NADH NADP succinyltransferase: carbamoyl L-ornithine synthase: ilvN oxidoreductase Gly-NH-CH - γ methyl-L-cysteine 2 diaminobutyrate SAVERM_RS18860 2-phospho- acetylmuramoyl-L-alanyl- -D- D-erythro-1- dapD phosphate 2-isopropylmalate SAVERM_RS14240 subunit beta: dehydrogenase: Gly-Gly-adenylate putrescine dAdoMet fumarate hydratase: D-gluconate branched-chain tryptophan C(O)-S-L-cysteine acetyltransferase: 3-oxoacyl-[acyl- glutamyl-L-lysyl- D-alanyl-D-alanine 2+ 2+ AICAR (imidazol-4- argininosuccinate SAVERM_RS08670 SAVERM_RS16665 D-glycerate gluconokinase: phosphate Co CorA Co synthase: leuA amino acid SAVERM_RS25160 synthase: trpB phosphate citrate synthase/ 2+ 2+ N-succinyl-2-amino- (S)-2-aceto-2- synthase: argG ectA carrier-protein] a (2E)-octadec-2-enoyl-[acp] SAVERM_RS34060 acetyltransferase: pta Mg Mg yl)-glycerol 6-ketopimelate ornithine aminotransferase: hydroxybutanoate SAVERM_RS31805 SAH glu fused MFS/ reductase: fabG acetyltransferase: pta methylcitrate class II fumarate 2-oxobutanoate (2S)-4-acetamido- UDP-N-acetyl-α-D- a 2-oxo 7,8-didemethyl- L-lactyl-2- a negatively 2251 a (1->4)- RS38330 3-phosphate carbamoyltransferase: (2S)-2- argininosuccinate hydratase: [+ 2 isozymes] 37 guanosine SAVERM_RS04665 ketol-acid adenylyltransferase/ spermidine synthase: 3-oxoacyl-[acyl- enoyl-ACP synthase: D-gluconate di-trans,octa-cis- γ 8-hydroxy-5- diphospho- 3-methylbutanoate hop-22(29)-ene SAM glycerophosphoglycerol DMAPP an adenosine adenosylcobinamide L-allo-threonine carbonic acid roseoflavin Ins(1)P phenylacetyl-CoA 5-deoxy-D-ribose α-D-glucan imidazoleglycerol- succinyldiaminopimelate SAVERM_RS18795 isopropylmalate synthase: 2-aminobutanoate CO H acetaldehyde SAVERM_RS16680 muramoyl-L-alanyl- -D- carboxylate ala UDP-N-acetyl- supercoiled DNA in 23S rRNA reductoisomerase: acetolactate adenosylhomocysteinase: SAVERM_RS27090 reductase 2 2 SAVERM_RS12665 6-phosphate undecaprenyl phosphate in tRNA bifunctional S-methyl-5- 1,4-alpha- Co 2+ Co 2+ phosphate transaminase: dapC branched-chain SAVERM_RS34805 trp sulfurtransferase carrier-protein] acetyl phosphate glutamyl-L-lysyl-D-alanine deazariboflavin 5'-guanosine bifunctional α-D-muramate DNA topoisomerase 23S rRNA inositol 2-phenylacetyl- RS10710 ornithine 3-isopropylmalate SAVERM_RS26050 ectoine synthase: [+ 3 isozymes] FabI: fabI citrate synthase: thioribose glucan 2+ 2+ dehydratase amino acid ilvC synthase: MoeZ: moeZ reductase: fabG ethanol fumarate adenosylcobinamide IV subunit A: (guanosine(2251) riboflavin kinase/ monophosphatase: CoA Mg Mg N-succinyl-L,L-2,6- carbamoyltransferase: dehydratase: [CysO sulfur- SAVERM_RS32890 [+ 2 isozymes] SAVERM_RS27515 2-oxoacid:ferredoxin acetate- glycerophosphodiester carbonic anhydrase: kinase: branching HisB: hisB aminotransferase: (R)-2,3-dihydroxy- L-arginino-succinate SAVERM_RS09600 acetate kinase: dehydrogenase: phospho-N- 2-phospho-L- adenosyl- tRNA (adenosine(37)-N6) kinase/ low specificity L- SAVERM_RS12645 -2'-O)- FAD synthetase: SAVERM_RS10210 epoxidase: diaminopimelate argF leuD leuC carrier protein] a (3R)-3- fumarate reductase/ Secondary Metabolite Degradation oxidoreductase -CoA phosphodiesterase: UDP-N- SAVERM_RS29185 mtnK enzyme: RS38140 3-(imidazol-4- SAVERM_RS14165 3-methylpentanoate acetolactate L-homocysteine ser ectoine spermidine SAVERM_RS14690 SAVERM_RS35715 acetylmuramoyl- lactate transferase: hopene -dimethylallyltransferase adenosylcobinamide- threonine aldolase: type I DNA methyltransferase SAVERM_RS13280 paaJ paaC α succinyl- superpathway of L-serine hydroxyhexadecanoyl-[acp] a stearoyl-[acp] subunit beta: ligase: acs SAVERM_RS21845 acetylmuramate-- inositol 5-deoxy- - 2+ 2+ yl)-2-oxopropyl dihydroxy-acid argininosuccinate synthase: ilvN succinate SAVERM_RS25990 transferase MiaA: miaA phosphate SAVERM_RS07905 topoisomerase: RlmB: rlmB [+ 3 isozymes] roseoflavin paaB paaA glgB Co Co 2-isopropylmaleate citrate pentapeptide- L-alanine ligase: 2-O- monophosphatase: 2-(1,2-epoxy-1,2- D-ribose 1- 2+ CorA 2+ diaminopimelate lyase: argH and glycine biosynthesis I 3-hydroxyacyl- ethanol dehydrogenase anhydromuropeptides recycling I SAVERM_RS25160 HpnH: hpnH [+ 7 isozymes] guanylyltransferase: 5'-phosphate Mg Mg phosphate dehydratase: SAVERM_RS14240 acetate transferase: topA 2251 starch desuccinylase: asp L-citrulline val L-proline biosynthesis cystathionine ACP dehydratase: flavoprotein subunit: L-idonate degradation SAVERM_RS11565 methylguanosine SAVERM_RS12560 dihydrophenyl) phosphate histidinol- 3-isopropylmalate ilvD aconitate hydratase 3-methylbutanoyl- 6 SAVERM_RS31080 SAVERM_RS16200 (S)-2-aceto-2- I (from L-glutamate) 3-phospho-D-glycerate SAVERM_RS18860 SAVERM_RS31515 oxidized diphosphate N -(3-methylbut- a relaxed DNA in 23S rRNA CO H O myo-inositol acetyl-CoA dehydratase: beta-synthase: SAVERM_RS25040 GlcNAc-1,6- a reduced CoA adenosyl-cobinamide 2 2 phosphate arg hydroxybutanoate ammonia assimilation cycle III AcnA: acnA + AMP 2-en-1-yl)- acetaldehyde (3S)-3-methyl-2- phosphoglycerate oleate β-oxidation Fatty Acid and Lipid Degradation an acyl-CoA CO H adenosyl hopane glycerol sn-glycerol gly UDP-N-acetyl-α-D- 2+ 2+ RS38025 SAVERM_RS18135 anhMurNAc- L-idonate 2 ferredoxin [iron- factor 420-0 GMP met Co Co transaminase: argininosuccinate leuD leuC oxopentanoate L-phenylalanine [+ 2 isozymes] testosterone degradation (anaerobic) undecaprenyl-diphospho-N 3-phosphate adenosine 37 phosphate RS16115 L,L-diaminopimelate 2-aceto-2-hydroxy- glu dehydrogenase: a (2E)-hexadec-2-enoyl-[acp] stearate L-Ala-γ-D-Glu- L-idonate 5- UMP muramoyl-L-alanine Mg 2+ Mg 2+ hisC (2R,3S)-3- biosynthesis I cis-aconitate γ sulfur] cluster synthase: argG branched-chain butanoate SAVERM_RS38415 ammonium Pentose Phosphate Pathways succinate dehydrogenase: -acetylmuramoyl-L-alanyl- - in tRNA isopropylmalate glutamate 5-kinase: oleate DAP-D-Ala histidinol-phosphate diaminopimelate argininosuccinate amino acid isomeroreductase: L-cystathionine phosphoglycerate enoyl-ACP long-chain fatty testosterone SAVERM_RS34045 D-glutamyl-L-lysyl- D-alanine transaminase: 3-isopropylmalate SAVERM_RS28245 chorismate reductase acid--CoA ligase: aconitate hydratase 5-dehydro- epimerase: synthase: aminotransferase: ilvC γ dehydrogenase: pentose phosphate pathway long-chain fatty 2+ 2+ L-tyrosine biosynthesis I -L-glutamyl chorismate mutase: 2-oxoglutarate glu AcnA: acnA Mg RS16130 Mg RS15450 SAVERM_RS31690 SAVERM_RS12895 SAVERM_RS34805 dehydrogenase: SAVERM_RS04665 (R)-2,3-dihydroxy- cystathionine SAVERM_RS14225 glutamate synthase FabI: fabI SAVERM_RS21755 acid--CoA ligase: 3-oxosteroid 1- D-gluconate a 2'- a 5'-phospho- 4-hydroxy- 5-phosphate SAVERM_RS25885 glutamine synthetase: ditrans,octacis-undecaprenyldiphospho- a pentaglycine cross- 6 6 (3Z)-hex- SAVERM_RS14170 gamma-lyase: D-glucopyranose dehydrogenase: a protein with MoO - N ,N -dimethyl- a ribonucleoside a single (S)-2- a uracil in DNA a D-tryptophanyl- an [RNA]- chitin an aryl sulfate DNA with lesion L(or D)-O- L-histidinol diaminopimelate 3-methylpentanoate 3-phosphooxypyruvate large subunit: gltB SAVERM_RS30690 [+ 2 isozymes] [+ 14 isozymes] D-threo-isocitrate SAVERM_RS21755 N-acetyl-β-D- L-alanyl-γ-D- 5-keto-D-gluconate N-acetyl-(N-acetylglucosaminyl) 2 deoxyribonucleoside glu ribonucleoside- 4-methyl-2- Ins(2)P a protein branched-chain glutamate-5- [+ 2 isozymes] bridge of peptidoglycan GTP L-arginine [DNA] triphosphate [tRNA Trp ] 3-en-1-ol epimerase: dapF L-arginino- (2S)-2-isopropyl- chorismate SAVERM_RS22095 6-phosphate SAVERM_RS08450 glucosamine-1,6- glutamyl-meso-2,6- 5-reductase: γ LAXTG motif molybdopterin 5'-triphosphate stranded DNA aminobutanoate 3'-hydroxyl [RNA] oxoglutarate CHAT domain- sulfatase: excinuclease phosphoserine phosphate amino acid dihydroxy-acid semialdehyde prephenate glutamate dehydrogenase: [+ 2 isozymes] stearoyl-CoA [+ 14 isozymes] muramoyl-L-alanyl- -D-isoglutaminyl- D-aspartate molybdopterin 4-carboxy-4-hydroxy- inositol succinate 3-oxosuccinate chorismate mutase: phosphoserine a palmitoyl-[acp] NADP-dependent SAVERM_RS34050 cofactor containing protein: SAVERM_RS29150 ABC subunit phosphoserine Na + RS23830 Na + histidinol- aminotransferase: dehydratase: ilvD dehydrogenase: SAVERM_RS08670 glucose-6-phosphate 1-dehydrotestosterone anhydro-N-acetyl- diaminopimeloyl- L-lysyl-D-alanyl-D-alanine beta-N- 2-oxoadipate monophosphatase: proteasome meso-diaminopimelate SAVERM_RS25885 prephenate cys transaminase: serC isocitrate oleoyl-CoA β-D-muramate D-alanine class E sortase: uracil-DNA SAVERM_RS11550 UvrB: uvrB phosphatase RS17985 phosphatase: argininosuccinate SAVERM_RS14165 SAVERM_RS28255 dehydrogenase: D-gluconate N(G),N(G)-dimethylarginine bifunctional DNA bifunctional DNA glutamate-- D-tyrosyl-tRNA(Tyr) RNA ligase (ATP): acetylhexosaminidase: aldolase/oxaloacetate sulfatase: SAVERM_RS10210 ATPase: arc [+ 2 isozymes] (3S)-3-methyl-2- dehydratase: L-threonine dehydrogenase: SAVERM_RS26865 molybdenum cofactor glycosylase: SerB: serB hisN lyase: argH imidazole glycerol SAVERM_RS09335 acyl-CoA/acyl-ACP beta-N- dimethylaminohydrolase: primase/polymerase: primase/polymerase: cysteine ligase: deacylase: SAVERM_RS33940 SAVERM_RS26485 decarboxylase: CHAT domain- SAVERM_RS41430 inositol excinuclease diaminopimelate prephenate oxopentanoate L-glutamate-5- pheA O-phospho-L-serine ammonium gln biosynthesis SAVERM_RS37060 D-aspartate ligase: guanylyltransferase: SAVERM_RS32125 an unfolded 4-methyl-2- ile phosphate glucose-6-phosphate dehydrogenase: acetylhexosaminidase: gluconokinase: [+ 3 isozymes] ddaH SAVERM_RS27045 SAVERM_RS27045 SAVERM_RS35920 SAVERM_RS20755 SAVERM_RS08570 containing protein: a phenol monophosphatase: ABC: uvrA uvrC serine Na + RS06335 Na + decarboxylase: branched-chain semialdehyde acyl-CoA hydrolysis SAVERM_RS25075 SAVERM_RS22570 [+ 2 isozymes] DNA without protein histidinol arg oxopentanoate prephenate 3-phenyl-2- synthase: hisH hisF dehydrogenase: 2-oxoglutarate SAVERM_RS22490 SAVERM_RS26485 L-alanyl-γ-D- SAVERM_RS34060 [+ 15 isozymes] [+ 8 isozymes] [+ 3 isozymes] N-acetyl-D- pyruvate SAVERM_RS16945 SAVERM_RS12560 SAVERM_RS18070 palmitate ∆ 1 lesion predicted amino acid oxopropanoate phosphoserine [+ 7 isozymes] L-homoserine SAVERM_RS32475 -dihydrotestosterone 1,6-anhydro-N- glutamyl-meso- [+ 2 isozymes] a protein with LAXT chitin (3Z)-hex-3- histidinol [+ 2 isozymes] branched-chain dehydrogenase: aminotransferase: glycine a 2,3,4-saturated [+ 8 isozymes] carboxyl end attached a peptide with an RNA glucosamine en-1-yl acetate myo-inositol ABC L-alanine phenylalanine phosphatase SerB: serB 6-phospho acetyl-β-muramate diaminopimelate D-gluconate ditrans,octacis-undecaprenyldiphospho- bis(guanylyl dimethylamine an apyrimidinic uracil Trp 2+ 2+ dehydrogenase: amino acid SAVERM_RS33530 biosynthesis IV homoserine kinase: long-chain fatty (2E,9Z)- N-terminal glycine L-citrulline ssDNA/pppN(pN) γ D-tryptophan a tRNA Co Co ectoine ectoine SAVERM_RS04665 transaminase: fatty acyl CoA D-glucono- N-acetyl-(N-acetylglucosaminyl)muramoyl- to a pentaglycine cross- molybdopterin) [DNA] -L-glutamyl-(S)- site in DNA RS03290 transporter hisD lys biosynthesis III aminotransferase: 3-(4- SAVERM_RS15145 acid--CoA ligase: acyl-CoA octadecenoyl-CoA 3-oxosteroid 1- anhydro-N- 6-phosphate hybrid Ni 2+ Ni 2+ (S)-1-pyrroline- γ β bridge of peptidoglycan n -1 2-aminobutanoate of ectoine alanine racemization hydroxyphenyl) branched-chain SAVERM_RS25330 ser O-phospho- SAVERM_RS21755 thioesterase: 1,5-lactone dehydrogenase: acetylmuramic L-alanyl- -D-isoglutaminyl-N-( -D- cofactor SAVERM_RS04665 5-carboxylate thr glu histidinal cys pyruvate amino acid L-homoserine [+ 14 isozymes] SAVERM_RS25935 6-phosphogluconolactonase: 1,17- SAVERM_RS08450 acid kinase: asparatyl)-L-lysyl-D-alanyl-D-alanine branched-chain pyrroline-5- phe threonine aldolase: serine RS36395 cysteine desulfurase: aminotransferase: [+ 5 isozymes] pgl dihydroxyandrostan- SAVERM_RS09035 Co 2+ Co 2+ amino acid SAVERM_RS24185 threonine synthase: a 2,3,4-saturated RS12195 histidinol ala SAVERM_RS14165 carboxylate hydroxymethyltransferase: palmitoyl-CoA N-acetyl-D- β 2+ 2+ SAVERM_RS32555 (S)-3-hydroxy-(9Z) 3-one androsta-1- superpathway of UDP-N-acetyl- undecaprenyldiphospho- a [prokaryotic 34 a thiocarboxylated a 2'- N-acetyl- -D- (R)-4-hydroxy- an [amino-group carrier Ni Ni dehydrogenase: aminotransferase: alanine racemase: reductase: low specificity L- SAVERM_RS14445 SAVERM_RS16525 fatty acid D-gluconate a uridine a Xaa-Pro dipeptidyl- a [DNA]-3'- benzoylsuccinyl- a [protein]-L- [+ 2 isozymes] TCA cycle -octadecenoyl-CoA ene-3,17-dione muramate 6- α-D-glucosamine pyruvate ubiquitin-like protein] [SAMP] C- deoxyribonucleoside glucosaminyl-(1 4-methyl-2- ω protein]-C-terminal-γ- propionamide acryloyl-CoA squalene SAVERM_RS14165 [+ 2 isozymes] 6-phosphate TCA cycle IV (2-oxoglutarate decarboxylase) D-glucarate and D- N-acetylmuramoyl-L- a [protein]-L-lysine in tRNA [DNA] hydroxyl a type IV prepilin CoA proline ( = 180) ATP repressor LexA hisD ala SAVERM_RS22190 ile proC threonine aldolase: [+ 2 isozymes] phosphate γ C-terminal L-glutamate terminal glycine 5'-triphosphate peptidase substrate -> 4)-N-acetyl- oxoglutarate FKBP-type amidase domain- crotonyl-CoA squalene tyr decarboxylating 6- 3-hydroxyacyl-CoA galactarate degradation alanyl- -D-glutamyl-meso 4-carboxy-4-hydroxy- (L-glutamyl)-L-glutamate alanine racemase: alr SAVERM_RS07905 thr N-acetylmuramic β-D-muramate peptidyl-prolyl cis- containing protein: adenylate/guanylate carboxylase/ transcriptional synthase RS36020 pro phosphogluconate oxaloacetate citrate synthase/ dehydrogenase: galactarate D-glucarate -2,6-diaminopimeloyl- 2-oxoadipate acetylglutamate a purine RS10610 a purine his leu D-ala gly gly 17-hydroxyandrostan- fatty acid β-oxidation I (generic) acid 6- pyruvate, tRNA 2- exodeoxyribonuclease benzoylsuccinyl- trans isomerase: SAVERM_RS32145 cyclase domain- reductase: repressor HpnC: dehydrogenase: gnd methylcitrate synthase: SAVERM_RS11710 D-alanyl-D-alanine bifunctional DNA Xaa-Pro dipeptidyl- aldolase/oxaloacetate kinase: argB 1,3-dione phosphate phosphate dikinase: Pup--protein III: xth prepilin peptidase: CoA thiolase: LexA: lexA hpnC SAVERM_RS12665 3-oxo-(9Z)- thiouridine(34) primase/polymerase: peptidase: beta-N- decarboxylase: SAVERM_RS34350 an [amino-group carrier [+ 4 isozymes] containing protein: ccrA [+ 2 isozymes] a (3Z)-alk-3- etherase: murQ undecaprenyldiphospho- SAVERM_RS29170 ligase: pafA synthase exodeoxyribonuclease SAVERM_RS24895 SAVERM_RS35785 SAVERM_RS17235 cleaved presqualene citrate synthase: octadecenoyl-CoA SAVERM_RS27045 SAVERM_RS08860 acetylhexosaminidase: SAVERM_RS08570 [+ 4 isozymes] protein]-C-terminal- propanoate [+ 2 isozymes] D-ribulose enoyl-CoA N-acetyl-D- muramoylpentapeptide beta-N- MnmA: mnmA III: xth a [protein]-L- cyclic-AMP (R)-methylmalonyl- repressor LexA diphosphate a purine RS08005 a purine SAVERM_RS27515 acetyl-CoA C- [+ 14 isozymes] SAVERM_RS26485 γ-(5-phospho-L- 5-phosphate glucosamine acetylglucosaminyltransferase: phosphoenol pyruvate proline (ω = 0) CoA SecF androstan- 5-dehydro-4- + N6-([prokaryotic glutamyl)-L-glutamate glutaminyl-tRNA gln Aminoacyl-tRNA Charging acyltransferase: 6-phosphate murG diphosphate H a dipeptide with a a cleaved type benzoyl-CoA succinyl-CoA malate dehydrogenase: AMP pyruvate ubiquitin-like protein]- a [SAMP] C- a 2-thiouridine 34 a [DNA]-3'- a 2'- a peptide ribose-5-phosphate SAVERM_RS11705 1,3,17-trione N-acetylglucosamine- deoxy-D-glucarate C-terminal L-proline a peptide N-acetyl-D- biosynthesis via transamidation ribulose- (S)-malate SAVERM_RS17775 citrate γ-L-glutamyl)- terminal glycine in tRNA [DNA] hydroxyl deoxyribonucleoside IV prepilin GlcNAc a sugar RS09280 a sugar phosphate 3- isomerase: acetyl-CoA C- 6-phosphate lipid II (meso UDP 5'-monophosphate muramate Secondary Metabolite Biosynthesis a (2E)-2- [protein]-L-lysine 2+ 2+ streptorubin B biosynthesis epimerase: SAVERM_RS28010 acyltransferase: deacetylase: nagA diaminopimelate containing) Zn RS29070 Zn glu methylerythritol phosphate pathway I actinorhodin biosynthesis fumarate hydratase: enoyl-CoA 3-hydroxyacyl- rpe SAVERM_RS16665 SAVERM_RS07380 D-glucosamine tartronate tRNA charging D-ribose 5- aconitate hydratase a 2,3,4-saturated CoA epimerase: a 2,3,4- long-chain fattyacyl-CoA/acyl-ACP 6-phosphate 6 predicted acetyl-CoA D-glyceraldehyde class II fumarate hydratase: saturated (3R)-3- semialdehyde N -(3-methylbut- 10 a methyl-esterified an [RNA] 38- pyruvate malonyl-CoA D-xylulose phosphate AcnA: acnA (7Z)-hexadecenoyl-CoA fatty acid dehydrogenase: SAVERM_RS11710 an L-methionyl- an N - a sulfurated [CysO sulfur- O-succinyl-L- a uridine an L-aspartyl- phosphoenol nitrate RS26410 nitrate 3-phosphate SAVERM_RS16680 acid--CoA ligase: hydroxyacyl-CoA phosphoglucosamine 2-hydroxy-3- a sulfurated [sulfur carrier] 2-en-1-yl)- phenylacetate succinate homogalacturonan containing aci-nitroethane succinate formyl-CoA L-threonine 3- pyrazinamide cys crotonyl-CoA a protein ABC gln ketoacyl-ACP 5-phosphate SAVERM_RS31885 [initiator tRNA Met ] formyltetrahydrofolate [sulfur carrier] carrier protein] homoserine 40 in tRNA [tRNA Asn ] pyruvate a sugar a sugar trp a tRNA Trp lys a tRNA Lys acyl-CoA/acyl-ACP SAVERM_RS24865 mutase: oxopropionate adenosine 37 in tRNA guanosine RluA family O-phosphate amidase domain- crotonyl-CoA pyruvate transporter synthase III: fumarate cis-aconitate [+ 8 isozymes] a 2,3,4- Asp-tRNA(Asn) cystathionine of a sugar an L-glutamyl- cys a tRNA Cys 1-deoxy-D-xylulose-5- dehydrogenase: [+ 14 isozymes] a 2,3,4-saturated SAVERM_RS25590 reductase: pseudouridine threonine-phosphate containing protein: carboxylase/ kinase: pyk hemin RS30685 hemin imidazole Gln SAVERM_RS29840 a 3,5,7,9,11,13,15-hepta- saturated (3S)-3- pectinesterase: formyl-CoA /Glu-tRNA(Gln) endopeptidase [tRNA ] ser Pro transketolase: aconitate hydratase SAVERM_RS22490 α ADP-forming succinate- nitronate SAVERM_RS32145 beta-synthase: ser a tRNA pro a tRNA phosphate synthase: oxo-hexadecanoyl-[PKS-acp] fatty acyl CoA -D-glucosamine SAVERM_RS10655 tRNA (N6-isopentenyl methionyl-tRNA adenylyltransferase/ phenylacetate-- SAVERM_RS32790 cystathionine synthase: decarboxylase: amidotransferase: reductase: La: lon pyruvate glycerol tryptophan- lysine--tRNA ligase: [+ 3 isozymes] SAVERM_RS08605 succinate dehydrogenase: AcnA: acnA hydroxyacyl-CoA -CoA ligase: sucD sucC ribonuclease N1: monooxygenase: transferase: SAVERM_RS18135 a sugar RS07745 a sugar Asp-tRNA(Asn) phe a tRNA Phe glu a tRNA glu tRNA asp asp elongator tRNA Met met initiator tRNA Met met arg a tRNA Arg ile a tRNA Ile thr a tRNA Thr SAVERM_RS08720 [+ 8 isozymes] 1-phosphate formyltransferase: sulfurtransferase CoA ligase: paaF gamma-synthase: SAVERM_RS31585 SAVERM_RS32930 gatB gatA gatC [+ 4 isozymes] ccrA kinase: pyk phosphate aldo/keto reductase: [+ 4 isozymes] 3-hydroxyacyl-CoA D-glycerate adenosine(37)-C2)- ADP-forming succinate- pectinesterase: SAVERM_RS35370 SAVERM_RS28750 frc (R)-1-amino- pyrazine-2- leu LeuE leu /Glu-tRNA(Gln) -tRNA SAVERM_RS24525 Val Leu Gly Tyr His Ala cysteinyl-tRNA SAVERM_RS37515 SAVERM_RS35345 MoeZ: moeZ SAVERM_RS17110 [+ 2 isozymes] an L-asparaginyl- [+ 2 isozymes] pyruvate synthase: val a tRNA leu a tRNA gly a tRNA tyr a tRNA his a tRNA a tRNA ala 1-deoxy-D-xylulose-5- (2E,7Z)- acetyl-CoA C- bifunctional UDP-N- methylthiotransferase SAVERM_RS32795 38- 2-propanol O lanthionine a peptide asn tRNA Asn gln a tRNA Gln serine--tRNA proline--tRNA ligase: ligase: trpS bifunctional synthetase: an acetoacetyl-[acp] SAVERM_RS29085 [+ 3 isozymes] dehydrogenase: -CoA ligase: sucD sucC [+ 3 isozymes] a pseudouridine [tRNA Asn ] carboxylate (2S)- hisH hisF amidotransferase: phosphate synthase: D-sedoheptulose D-glyceraldehyde hexadecenoyl-CoA acyltransferase: acetylglucosamine MiaB: miaB -2-phosphate phenylalanine-- ligase: serS SAVERM_RS13345 glutamate-- tryptophan- aspartate- methionine-- methionine-- arginine- lysylphosphatidylglycerol isoleucine-- threonine-- SAVERM_RS36220 [+ 21 isozymes] coenzyme A SAVERM_RS11710 glycerate kinase: a 5'-hydroxy- an [RNA]-3'- 40 in tRNA ethylmalonyl-CoA a sugar RS09645 a sugar gatB gatA gatC 3-oxoacyl-[acyl- SAVERM_RS11760 7-phosphate 3-phosphate SAVERM_RS07380 diphosphorylase/ an N-formyl- a [CysO sulfur- phenylacetyl-CoA diphosphate formate succinyl-CoA potassium- [+ 7 isozymes] a 5-phosphooxy- tRNA ligase: pheS serine--tRNA proline--tRNA ligase: tRNA ligase: -tRNA -tRNA tRNA ligase: tRNA ligase: -tRNA synthetase/lysine-- valine--tRNA ligase: leucine--tRNA ligase: glycine--tRNA ligase: tRNA ligase: tyrosine--tRNA ligase: tRNA ligase: histidine--tRNA ligase: alanine--tRNA cysteine--tRNA ligase: 9-hydroxy-3,5,7,11,13,15- a 2,3,4-saturated a 2,3,4-saturated SAVERM_RS10105 a tetrahydrofolate an unsulfurated AMP succinate ribonucleotide- guanosine- succinate D-threo-isocitrate glucosamine-1- N 6 -(3-methylbut-2-en- L-methionyl- carrier protein]- a homogalacturonan MeOH L-homocysteine K + transporting K + carrier-protein] NADP-dependent acetyl-CoA C- ADP phosphate succinyl-CoA acetaldehyde nitrite L-glutamyl- SAVERM_RS34630 ligase: serS SAVERM_RS13775 SAVERM_RS14035 ligase: trpS ligase: aspS SAVERM_RS22760 SAVERM_RS22760 ligase: argS tRNA ligase LysX: lysX SAVERM_RS28145 SAVERM_RS28335 SAVERM_RS29075 SAVERM_RS31570 SAVERM_RS33205 SAVERM_RS35060 SAVERM_RS35175 ligase: alaS SAVERM_RS20475 hexaoxohexadecanoyl-[PKS-acp] fatty acyl CoA 3-oxoacyl-CoA 2-phospho- an unsulfurated met [sulfur carrier] 3'-[RNA] 3'-phosphate ammonium reductase: fabG 1-deoxy-D-xylulose transaldolase: tal acyltransferase: phosphate N- 5'-deoxyadenosine 1-yl)-2-(methylsulfanyl) met [initiator tRNA ] thiocarboxylate ATPase [tRNA Gln ] neopentalenoketolactone and pentalenate biosynthesis isocitrate dehydrogenase: (S)-3-hydroxy-(7Z) D-glycerate 5-phosphate succinate-semialdehyde acetyltransferase adenosine 37 in tRNA [sulfur carrier] 3-oxoacyl-[acyl- transaldolase: tal SAVERM_RS37060 -hexadecenoyl-CoA SAVERM_RS11705 predicted an L-phenylalanyl- an L-asparaginyl- an L-glutaminyl- an L-tryptophanyl- an L-methionyl- an L-methionyl- 1-deoxy-D-xylulose- dehydrogenase (NADP(+) GlmU: glmU thiamine RS13645 thiamine Asp-tRNA(Asn) an L-seryl-[tRNA ser ] an L-prolyl-[tRNA Pro ] an L-glutamyl-[tRNA Glu ] an L-aspartyl-[tRNA asp ] an L-arginyl-[tRNA Arg ] an L-lysyl-[tRNA Lys ] an L-valyl-[tRNA Val ] an L-leucyl-[tRNA Leu ] a glycyl-[tRNA Gly ] an L-isoleucyl-[tRNA Ile ] an L-tyrosyl-[tRNA Tyr ] an L-threonyl-[tRNA Thr ] an L-histidyl-[tRNA His ] an L-alanyl-[tRNA Ala ] an L-cysteinyl-[tRNA Cys ] carrier-protein] ABC [tRNA Phe ] [tRNA Asn ] [tRNA Gln ] [tRNA Trp ] [elongator tRNA Met ] [initiator tRNA Met ] (2E,6E)-farnesyl NADH repair (prokaryotes) ): SAVERM_RS25870 3-hydroxyacyl-CoA α a sugar a sugar /Glu-tRNA(Gln) reductase: fabG 5-phosphate a (3'-hydroxy-2'-(3''- D-erythrose N-acetyl- -D- 6-O-cis-methoxy- transporter diphosphate F6P dehydrogenase: a [2-oxoglutarate- lysine within RNase III mRNA β-D-fructofuranose a [release factor]- a guanine 527 a uracil 1498 L-malic reductoisomerase: 4-phosphate glucosamine a sulfurated UDP-N-acetyl-α-D-muramoyl- D-alanyl-D-alanine isobutanoate 2-methylbutanoate a D-aminoacyl- leukotriene-D4 malonyl-CoA H + squalene of a sugar amidotransferase: a (3R)-3- oxobutanoyl)phenyl)-3,5- SAVERM_RS11710 phospholipases SAM dehydrogenase gcv protein H an octanoyl-[acp] processing 1-phosphate L-ornithine his mycolyl-trehalose SAVERM_RS13370 pentalenene NADH 1-phosphate [sulfur carrier] L-alanyl-γ-D-glutamyl-L-lysine [tRNA] L-glutamine in 16S rRNA in 16S rRNA semialdehyde gatB gatA gatC dioxohexanethioate-[PKS-acp] transketolase: succinate semialdehyde 2-oxoglutarate acetyl-CoA N-acetylglucosamine E2 protein] N 6 - substrate peptide chain 16S rRNA 16S rRNA aldehyde 6-phosphate squalene- RS10030 hydroxybutanoyl-[acp] synthase: 3-oxo-(7Z)- a 1,2-diacyl- SAVERM_RS08605 bifunctional UDP-N- degradation I octanoyl-L-lysine release factor (guanine(527)-N(7) (uracil(1498)-N(3))- dehydrogenase ornithine L-histidine N(alpha) trehalose- -hopene a sugar RS30810 a sugar 3-hydroxyacyl- MEP SAVERM_RS15575 hexadecenoyl-CoA a phosphatidylcholine sn-glycerol acetylglucosamine UDP-N-acetylmuramoyl- acetate- membrane type III polyketide class II fructose- cyclodeaminase: -methyltransferase: phosphatase: an L-glutaminyl- [+ 4 isozymes] lipoyl(octanoyl) acetate--CoA D-tyrosyl-tRNA(Tyr) N(5)-glutamine )-methyltransferase methyltransferase: (NADP(+)): cyclase: Nucleoside and Nucleotide Biosynthesis ACP dehydratase: acetyl-CoA C- 3-phosphate diphosphorylase/ N-acetyl-D- tripeptide--D-alanyl- -CoA ribonuclease III: dipeptidase: synthase: bisphosphate SAVERM_RS28985 egtD otsB Gln pentalenene D-glyceraldehyde lipoyl transferase ligase: acs methyltransferase: RsmG: rsmG SAVERM_RS28755 SAVERM_RS32855 shc [tRNA ] SAVERM_RS18860 2-C-methyl-D- 4-(3'-acetyl-5'-hydroxy-4'-oxo- acyltransferase: glucosamine ligase: acs deacylase: SAVERM_RS25905 SAVERM_RS36630 aldolase: fbaA an N 7 - an N 3 - trehalose- 3-phosphate glucosamine-1- synthase: D- alanine ligase: LipB: lipB SAVERM_RS13875 prmC erythritol 4-phosphate 1',4'-dihydronapthalen-2'-yl) multifunctional oxoglutarate 6-phosphateN-acetylglucosamine- SAVERM_RS20755 methylguanine 527 methyluracil 1498 (S)-malate pro hercynine cis-methoxy- hop-22(29)-ene a sugar RS05345 a sugar pentalenene (R)-NADHX SAVERM_RS11705 a 1-acyl-sn phosphate N- SAVERM_RS31510 a [release factor]-N 5 RS17640 superpathway of pyrimidine cytidylyltransferase: -3-oxobutanoate-[PKS-acp] decarboxylase/oxoglutarate lipA mono-mycolate superpathway of guanosine inosine-5'-phosphate biosynthesis I guanine and guanosine salvage 5-aminoimidazole ribonucleotide biosynthesis I adenine and adenosine salvage III guanine and guanosine salvage II a (2E)-but-2-enoyl-[acp] oxygenase: acetyl-CoA C- a phosphatidylcholine -glycero-3- acetyltransferase 6-phosphate a [glycine-cleavage (2S)-2- -methyl-L-glutamine in 16S rRNA in 16S rRNA ribonucleotides de novo biosynthesis superpathway of SAVERM_RS20485 bifunctional ADP- dehydrogenase thiamine isobutanoyl-CoA RNase III D-glyceraldehyde nucleotides de novo biosynthesis I SAVERM_RS15580 acyltransferase: phosphocholine GlmU: glmU D-glucosaminedeacetylase: nagA a [2-oxoglutarate α acyl-carrier protein complex H protein] diphosphate methylbutanoyl- diphosphate leukotriene-E4 gly octoketide DHAP adenosine nucleotides enoyl-ACP 4-(cytidine 5'- dependent NAD(P)H- pyrophosphate-binding 5'-deoxyadenosine an unsulfurated UDP-N-acetyl- -D-muramoyl-L-alanyl- AMP AMP an mRNA fragment processing an uncharged de novo biosynthesis I PRPP xanthine and hydrate dehydratase/ SAVERM_RS07380 UDP-N-acetyl- 6-phosphate met dehydrogenase γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine N 6 -octanoyl-L-lysine CoA a D-amino acid tRNA a sugar RS10445 a sugar gln AIR reductase diphospho)-2-C- pentalen-13-ol subunit/dihydrolipoyllysine- 6 [sulfur carrier] product mRNA hydrogencarbonate guanosine adenine guanosine xanthosine salvage 4-(3'-acetyl-5'-hydroxy-4'- NAD(P)H-hydrate a 2-acyl-sn α-D-glucosamine E2 protein] N RS36105 IMP 5-(carboxyamino)imidazole FabI: fabI methyl-D-erythritol oxo-1',4'-dihydronapthalen- residue succinyltransferase (5Z)-tetradecenoyl-CoA a phosphatidylcholine -glycero-3- -lipoyl-L-lysine IMP ribonucleotide synthase: purine-nucleoside amidophosphoribosyltransferase: purine-nucleoside 4-(cytidine 5'- pantalen-13- epimerase: subunit: SAVERM_RS15455 UDP-N-acetylglucosamine asp SAVERM_RS21355 phosphorylase: [+ 2 isozymes] 2'-yl)-3-oxobutanoate phosphocholine IMP SAVERM_RS25895 phosphorylase: diphospho)- ol oxygenase: (S)-NADHX SAVERM_RS25620 acyl-CoA/acyl-ACP 1-carboxyvinyltransferase: α-D-glucosamine a sugar RS05890 a sugar glutamine- SAVERM_RS17295 xanthosine hydroxylacyl-CoA dehydrogenase: N5-CAIR SAVERM_RS17295 5-phospho-β- gly 2-C-methyl-D- SAVERM_RS15580 dehydrogenase: SAVERM_RS11835 6-phosphate an L-1- an [HPr]- phosphoenol an 1-acyl-2- an (R)-2- dCDP a guanine 966 a [protein]-L- a (2E,4Z)-2,4- 6-O-trans-keto- hydrolyzing guanine adenosine guanine a butanoyl-[acp] dehydrogenase: phospholipase C, an L-lysyl- CDP-choline methanethiol O-succinyl-L- O-succinyl-L- 3-sulfocatechol canavaninosuccinate trans-aconitate purine-nucleoside bifunctional ADP- Lys phosphatidyl- arachidonoyl- cys a tRNA precursor β cys mycolyl-trehalose gly carbamoyl- adenylosuccinate guaB D-ribosylamine erythritol kinase: SAVERM_RS07210 SAVERM_RS31885 UDP-N-acetylglucosamine glucosamine- [tRNA ] L-histidine pyruvate homoserine homoserine halocarboxylate vitamin B12-dependent in 16S rRNA -isoaspartate dienoyl-CoA GTP phosphorylase: pentalen-13-al dependent NAD(P)H- phosphocholine- sn-glycerol sn-glycerol 16S rRNA protein-L- NADPH-dependent 6-phosphate RS36585 phosphate synthase: 5-(carboxyamino)imidazole beta-ketoacyl- SAVERM_RS18525 (S)-4-(3'-acetyl-5'-hydroxy-4'- [+ 8 isozymes] 1-carboxyvinyltransferase: 6-phosphate ribonucleotide reductase: trans-aconitate 2- adenosine deaminase: SAVERM_RS17295 hydrate dehydratase/ specific: (guanine(966)-N(2) isoaspartate O- 2,4-dienoyl- cystathionine trehalose- glycine predicted synthase: SAVERM_RS23495 XMP ribonucleotide mutase: purE hypoxanthine phosphoribosylamine- hypoxanthine xanthine ACP synthase 2-phospho-4-(cytidine oxo-1',4'-dihydronapthalen- pantalen-13- (2E,5Z)- murA deaminase: phosphoenolpyruvate- catechol 2,3- SAVERM_RS12835 methyltransferase: diguanylate cyclase: SAVERM_RS06315 NAD(P)H-hydrate SAVERM_RS09065 chloramphenicol cystathionine HAD family hydrolase: argininosuccinate )-methyltransferase methyltransferase: CoA reductase: beta-synthase: phosphatase: oxidase ABC carA carB phosphoribosyltransferase: hpt -glycine ligase: purD phosphoribosyltransferase: hpt II: fabF 5'-diphospho)-2-C- 2'-yl)-3-hydroxybutanoate al oxygenase: tetradecenoyl-CoA a 1,2-diacyl- UDP-N-acetyl-α- nagB bifunctional -protein cystathionine dioxygenase: SAVERM_RS18445 SAVERM_RS40815 a sugar a sugar CAIR [+ 4 isozymes] epimerase: a phosphatidylcholine phosphotransferase gamma-synthase: SAVERM_RS24410 ribonuclease Z: ribonucleoside- lyase: argH (E)-3- RsmD: rsmD SAVERM_RS01415 SAVERM_RS06930 SAVERM_RS18135 otsB ThiO: thiO transporter glutamine- [+ 2 isozymes] methyl-D-erythritol SAVERM_RS15580 sn-glycerol D-glucosamine- lysylphosphatidylglycerol phosphotransferase: ptsP gamma-synthase: SAVERM_RS08560 an N 2 - a protein L-β- [+ 2 isozymes] trehalose- adenylo-succinate 2-C-methyl-D- SAVERM_RS25620 CPT: cpt SAVERM_RS17110 [+ 9 isozymes] SAVERM_RS28775 diphosphate reductase: (methoxycarbonyl) a (2E)-2- glyoxylate of a sugar carbamoyl hydrolyzing GMP GAR enolpyruvate F6P synthetase/lysine-- SAVERM_RS17110 methylguanine 966 isoaspartate c-di-GMP ser trans-keto- RS05925 asp phosphoribosylaminoimidazolesuccinocarboxamide GMP inosine GMP erythritol 2,4- 1-deoxypentalenate SAVERM_RS15715 pent-2-enedioate enoyl-CoA phosphate adenylosuccinate synthase: guaA a 3-oxohexanoyl-[acp] 2-((1R,3S),-1',9'-dihydroxy- a 1-phosphatidyl- UDP-N- tRNA ligase LysX: lysX an [HPr protein]- (2Z,4E)-2- in 16S rRNA α-methyl ester mono-mycolate synthase: SAVERM_RS21425 cyclodiphosphate NADH a 1,2-diacyl- a 1-acyl-2- CMP an (S)-2- SAVERM_RS15720 predicted lyase: phosphoribosylglycinamide 1'-methyl-10'-oxo- 1D-myo-inositol π pyruvate succinate a single-stranded sulfite L-canavanine fumarate purine-nucleoside XMP synthase: (3E,5Z)-tetradeca- (S)-3-hydroxy-(5Z) sn-glycerol acetylmuramate N -phospho- arachidonoyl- met a halide anion hydroxyhexa- CDP ABC SAVERM_RS10055 GMP formyltransferase: 3-oxoacyl-[acyl- 3',4',5',10'-tetrahydro-1H- 4,5-bisphosphate L-cystathionine succinate hydroxycarboxylate mature tRNA oligoribonucleotide a sugar a sugar aspartate SAICAR phosphorylase: SAVERM_RS20480 1-deoxypentalenic 1-deoxypentalenate 3,5-dienoyl-CoA -tetradecenoyl-CoA dehydrogenase: 3-O-L-lysyl-1-O- L-histidine phosphatidylcholine 2,4-dienedioate transporter SAVERM_RS17820 carrier-protein] a tRNA Lys carbamoyltransferase adenylosuccinate SAVERM_RS17295 benzo[g]isochromen-3'-yl)acetate acid 11-beta- 1-hydroxylase: 3-hydroxyacyl-CoA SAVERM_RS25320 phosphatidylglycerol of a sugar adenylosuccinate lyase: reductase: fabG 2-C-methyl-D-erythritol- acyl-CoA Aromatic Compound Degradation Chlorinated RS18125 catalytic subunit: lyase: FGAR hydroxylase: ptlH SAVERM_RS02570 thioesterase: dehydrogenase: UDP-N-acetyl- Compound Degradation guanylate SAVERM_RS10055 3-oxoacyl-[acyl- 2,4-cyclodiphosphate α SAVERM_RS35275 SAVERM_RS36360 pyrimidine deoxyribonucleotides de novo biosynthesis III hypoxanthine SAVERM_RS25935 SAVERM_RS11710 -D-muramate predicted kinase: gmk adenylosuccinate lyase: carrier-protein] β cinnamate and 3-hydroxycinnamate phosphoribosylformylglycinamidine flavodoxin- 1-deoxy-11 - catechol degradation to 2- protocatechuate degradation parathion degradation 1,2-dichloroethane GDP-α-D- trans,octacis a mature peptidoglycan a 1-acyl,2-oleoyl- a 1-palmitoyl-2- an N-formyl-L- an (S)-2- a single- UDP an N-terminal L- a monocarboxylic 3-oxo-23,24- a (2E,4E)-2,4- a [protein]- 5-(methylsulfanyl) 4-methyl-3- ABC reductase: fabG pentalenate [+ 5 isozymes] 3-oxo-(5Z)- degradation to 2-hydroxypentadienoate (n) CDP-choline CDP-choline an alkylated DNA N-formimino- a sugar a sugar SAVERM_RS36360 UDP CTP synthase: purL purQ purS dependent (S)-DNPA hydroxypentalenate hydroxypentadienoate II II (ortho-cleavage pathway) degradation mannose -decaprenyl (meso-DAP containing) methionylaminoacyl- alanyl-[S18 protein bisnorchol-4- -2,3-dioxopentyl oxoadipate- D-ala transporter N-carbamoyl- AMP hypoxanthine (3E,5Z)- tetradecenoyl-CoA sn-glycerol acyl-sn-glycerol halocarboxylate stranded RNA vitamin B12-dependent acid amide L-glutamate dienoyl-CoA L-histidine GDP ribonucleoside- a (3R)-3- (E)-4-hydroxy- 1-deoxy-11-beta- phosphate tRNA of 30S ribosome]ribosomal protein amidase domain- en-22-oyl-CoA NADPH-dependent histidine kinase: 1-phosphate enol-lactone of a sugar RS38020 L-aspartate AICAR phosphoribosyltransferase: hpt tetradecadienoate acetyl-CoA C- cinnamate parathion UDP-N-acetyl- ribonucleotide reductase: formimidoylglutamate 3-oxosteroid 1- 3-oxoadipate glycine diphosphate reductase: FGAM hydroxyhexanoyl-[acp] 3-methylbut- hydroxypentalenate myo-inositol biosynthesis catechol protocatechuate 1,2-dichloroethane S18-alanine N- containing protein: 2,4-dienoyl- SAVERM_RS31325 acireductone acyltransferase: α-D-muramoyl- lytic transglycosylase chloramphenicol chloramphenicol HAD family hydrolase: polyribonucleotide DNA-3-methyladenine SAVERM_RS12835 deiminase: dehydrogenase: enol- oxidase dihydroorotase: adenylate kinase: bifunctional SAVERM_RS15715 CDP 2-enyl- dehydrogenase: ptlF catechol 2,3- protocatechuate haloalkane polyprenol acetyltransferase: SAVERM_RS32145 CoA reductase: synthase: mtnC predicted phosphoribosylformylglycinamidine 3-hydroxyacyl- SAVERM_RS07380 L-alanyl-γ-D- domain-containing protein: phosphotransferase phosphotransferase peptide deformylase: SAVERM_RS24410 nucleotidyltransferase: glycosylase: SAVERM_RS18055 SAVERM_RS08450 [+ 4 isozymes] lactonase: ThiO: thiO SAVERM_RS35280 SAVERM_RS25530 nucleoside- ribonucleoside- phosphoribosylaminoimidazolecarboxamide SAVERM_RS15720 IMP diphosphate 1-deoxy-11- D-glucopyranose bifunctional 3- dioxygenase: 3,4-dioxygenase: phosphotriesterase: dehalogenase: monophosphomannose ribonucleoside- rimI [+ 4 isozymes] 3-oxo-23,24- SAVERM_RS06930 a [protein]- 1,2-dihydroxy-5- ABC ribonucleoside- cyclo-ligase: SAVERM_RS21350 ACP dehydratase: 5-deoxy-dihydrokalafungin acetyl-CoA C- glutamyl-meso-2,6- SAVERM_RS30135 CPT: cpt CPT: cpt SAVERM_RS37735 [+ 9 isozymes] SAVERM_RS13170 SAVERM_RS33335 an N-terminal N-acetyl- a (2E)-2- pcaD a sugar a sugar diphosphate diphosphate formyltransferase/IMP cyclohydrolase: purH synthase: ispG oxopentalenate 6-phosphate phenylpropionate/ SAVERM_RS08560 pcaH pcaG SAVERM_RS07670 SAVERM_RS24675 synthase: diphosphate reductase: a monocarboxylate N-formyl- bisnorchol-1,4- N-phospho- (methylsulfanyl) 4-methyl-3- pyruvate transporter ADP vitamin B12-dependent diphosphate reductase: superpathway of pyrimidine SAVERM_RS18860 inositol-3-phosphate acyltransferase: diaminopimelate 2-chloroethanol [+ 5 isozymes] [+ 2 isozymes] L-alanyl-[S18 protein enoyl-CoA RS14050 (S)-dihydroorotate kinase: ndk reductase: cinnamic acid HMS 3-carboxy-cis,cis-muconate SAVERM_RS35565 SAVERM_RS15715 L-glutamate dien-22-yl-CoA L-histidine pent-1-en-3-one oxoadipate of a sugar FAICAR ribonucleotide reductase: SAVERM_RS15715 AIR nucleobases salvage flavodoxin- 1-deoxy-11- synthase: SAVERM_RS11705 3-hydroxycinnamate a 1-acyl-2-oleoyl- a 1-palmitoyl-2- a DNA containing of 30S ribosome] SAVERM_RS15715 a (2E)-hex-2-enoyl-[acp] dioxygenase CMP CMP an (S)-2- a nucleoside a single- an alkylated SAVERM_RS15720 vitamin B12- SAVERM_RS12835 SAVERM_RS15720 dependent oxopentalenate SAVERM_RS22210 3-carboxy- diethylthiophosphate 4-nitrophenol trans,octacis- a mature peptidoglycan GlcNAc-1,6-anhMurNAc- sn-glycero-3- acyl-sn-glycero-3- a halide anion an apurinic/ quinone-dependent uracil (3Z)-dodec- ferredoxin subunit: (n) a L-methionylaminoacyl- hydroxycarboxylate stranded RNA nucleobase dUDP dependent SAVERM_RS15720 bifunctional dUDP vitamin B12-dependent (E)-4-hydroxy- 22-[(1R,3S)-5,9,10- monooxygenase Ins(3)P cis,cis-muconate decaprenylphospho- (meso-DAP containing) L-Ala-γ-D-Glu-DAP-D-Ala phosphocholine phosphocholine formate diphosphate apyrimidinic site predicted dihydroorotate GTP uracil enoyl-ACP 3-enoyl-CoA SAVERM_RS32545 GDP tRNA ABC ribonucleotide vitamin B12- phosphoribosylaminoimidazolecarboxamide nucleoside- ribonucleotide reductase: 3-methylbut- trihydroxy-1-methyl-1H,3H,4H- (neopentalenolactone (2Z,4E)-2- cycloisomerase: pcaB β-D-mannose a sugar a sugar dehydrogenase: phosphoribosyltransferase: upp reductase ∆3,∆2-enoyl- 4-sulfocatechol transporter reductase: dependent formyltransferase/IMP cyclohydrolase: purH diphosphate kinase: ndk SAVERM_RS12835 2-enyl- naphtho[2,3-c]pyran-3-yl]acetate D producing): inositol bifunctional 3- hydroxyhexa- (2-carboxy-2,5-dihydro- chloroacetaldehyde RS38220 SAVERM_RS35300 bifunctional pyr operon FabI: fabI CoA isomerase: degradation of a sugar SAVERM_RS12835 ribonucleotide diphosphate SAVERM_RS15560 monophosphatase: phenylpropionate/ 2,4-dienedioate 5-oxofuran-2-yl)-acetate PRPP dUTP dCDP transcriptional regulator/uracil [+ 2 isozymes] SAVERM_RS11710 chlorpyrifos degradation aldehyde orotate reductase: cinnamic acid 34 ribonucleoside- IMP superpathway of pyrimidine deoxyribonucleoside salvage synthase: ispG SAVERM_RS10210 4-sulfocatechol 4-carboxymuconolactone diethylphosphate a 7-aminomethyl-7- a single 1,2-dipalmitoyl- a [protein]-S- a uridine a 1-(1-alkenyl) a cytidine 1402 (indol-3-yl) a guanine 46 dUTP diphosphatase: dut nucleoside- phosphoribosyltransferase neopentalenolactone D (2E)-dodec- dehydrogenase 34 CDP-choline coenzyme A FMN NAD(P)H H + 2-oxoglutarate ectoine 3'-ketolactose a dipeptide an aldehyde a 28S rRNA histidinol predicted diphosphate SAVERM_RS12835 (E)-4-hydroxy-3- inositol dioxygenase deazaguanosine SAM stranded DNA sn-glycerol VibB sulfanyl-L-cysteine in tRNA -sn-glycero-3- in 16S rRNA acetamide in tRNA Ap4A orotate diphosphate kinase: ndk PyrR: pyrR a hexanoyl-[acp] 2-enoyl-CoA protocatechuate decarboxylase: pcaC (NADP(+)): ABC reductase: nucleoside triphosphate 2'-deoxycytidine methylbut-2-en- THN neopentalenolactone monophosphatase: ferredoxin subunit: chlorpyrifos in tRNA phosphocholine 16S rRNA amidase domain- tRNA membrane aldehyde RICIN domain- diadenosine histidinol a sugar a sugar phosphoribosyltransferase: UMP (3E)-2-oxohex- 3,4-dioxygenase: (4,5-dihydro-5- SAVERM_RS32855 transporter RS03255 SAVERM_RS15715 pyrophosphohydrolase: dCTP beta-ketoacyl- 1-yl diphosphate D dioxygenase: SAVERM_RS12560 SAVERM_RS35725 phosphotriesterase: (cytidine(1402)-2'-O) containing protein: (guanosine(46)-N7) dipeptidase: dehydrogenase containing protein: tetraphosphate dehydrogenase: SAVERM_RS23360 3-enedioate pcaH pcaG oxofuran-2-yl)-acetate exodeoxyribonuclease chloramphenicol tRNA 2- FMN reductase: ectoine beta-glucosidase: of a sugar SAVERM_RS15720 dGDP SAVERM_RS18275 nucleoside deaminase: UMP kinase: ACP synthase SAVERM_RS15565 3-sulfomuconate SAVERM_RS07670 2-chloroacetate S-adenosylmethionine:tRNA holo-ACP synthase: SAVERM_RS09500 -methyltransferase: SAVERM_RS32145 -methyltransferase SAVERM_RS25905 (NADP(+)): SAVERM_RS05620 hydrolase: hisD SAVERM_RS13670 myo-inositol (2E)-3-(5,6- VII: SAVERM_RS16630 phosphotransferase thiouridine(34) SAVERM_RS24600 lysoplasmalogenase: hydroxylase: rsmI TrmB: trmB SAVERM_RS32855 adenine and dUMP SAVERM_RS24805 II: fabF (S)-3- 3-oxoadipate enol- diethylthiophosphate ribosyltransferase-isomerase: SAVERM_RS25615 a 2'-O- [+ 4 isozymes] an N 7 - [+ 2 isozymes] SAVERM_RS02965 1-hydroxy-2- neopentalenolactone E dihydroxycyclohexa- haloacid SAVERM_RS16635 CPT: cpt synthase [+ 3 isozymes] SAVERM_RS33145 thpD [+ 2 isozymes] a proteinogenic a 28S rRNA predicted orotidine 5'- nucleoside- [+ 5 isozymes] 3-sulfomuconate lactonase: pcaD catechol degradation to 1402 (indol-3-yl)acetate 46 a carboxylate his dADP adenosine salvage I dCMP UDP [+ 2 isozymes] methyl-2-butenyl actinorhodin hydroxydodecanoyl-CoA SAVERM_RS33275 MnmA: mnmA methylcytidine methylguanine amino acid ADP ABC phosphate diphosphate FAD-dependent 1,3-dien-1-yl) (2Z)-2- cycloisomerase: 2-hydroxypentadienoate I dehalogenase type fragments a sugar a sugar RS11240 nucleoside- 4-diphosphate neopentalenolactone enoyl-CoA 1,2-dipalmitoyl- 3-keto-β-D- in 16S rRNA in tRNA transporter kinase: ndk thymidylate synthase: 2'-deoxyuridine (d)CMP kinase: prop-2-enoate hydroxypenta- pcaB 3-oxoadipate II: SAVERM_RS04165 a ribonucleoside a single-stranded CMP a holo-[VibB aryl- D-glucopyranose a 3-oxooctanoyl-[acp] reductase: 34 3',5'-ADP + sn-glycero-3- 5-hydroxyectoine succinate orotidine-5'- nucleoside- SAVERM_RS13140 SAVERM_RS33535 diphosphate kinase: ndk E dioxygenase: hydratase/isomerase an epoxyqueuosine sn-glycero-3- 34 FMNH NAD(P) galactose of a sugar adenosine 2,4-dienoate catechol paraoxon degradation 5'-monophosphate oligodeoxyribonucleotide carrier protein] a [protein]- a 2-thiouridine 2 a fatty aldehyde phosphate diphosphate 1-hydroxy-2- SAVERM_RS08735 SAVERM_RS15565 family protein: 4-sulfomuconolactone glycolate adenine met in tRNA phosphocholine phosphocholine dGTP purine-nucleoside dTMP thymidine kinase: dCDP UTP 3-oxoacyl-[acyl- L-cysteine in tRNA decarboxylase: kinase: ndk methyl-2-butenyl 4-hydroxy-3-methylbut- SAVERM_RS11710 catechol 2,3- diethylphosphate predicted phosphorylase: SAVERM_RS12600 carrier-protein] neopentalenolactone F paraoxon pyrF nucleoside- CTP synthase: 4-diphosphate 2-enyl diphosphate dioxygenase: ABC RS18765 SAVERM_RS17295 dTMP kinase: tmk thymidine SAVERM_RS33445 reductase: fabG 3-oxododecanoyl-CoA 2,3-dihydroxy- a sugar a sugar dATP diphosphate kinase: ndk pyrimidine ribonucleosides salvage I reductase: reductase: methyl parathion degradation SAVERM_RS08560 transporter UMP adenine dUMP 3-oxoacyl-[acyl- trans-cinnamate dTDP CTP SAVERM_RS08735 SAVERM_RS16625 phosphotriesterase: an L-1- an (S-diacyl-sn- all-trans- an N-acetyl-β- an α(1,5)- a cytidine 1402 guanine 37 of a sugar dCTP acetyl-CoA C- HMS hydrogen selenide coenzyme A [EntB aryl- a homogalacturonan NADP + FMNH HMG-CoA (S)-5-hydroxyisourate 5-hydroxy- acetamide a uridine in tRNA long chain UMP kinase: thymidine kinase: cytidine carrier-protein] 2-maleylacetate glyceryl)-L-cysteinyl- O-acetyl-L-serine octaprenyl 2 D-hexosaminide L-arabinan D-ala Phe CMP phosphorylation adenine 4-hydroxy-3-methylbut- acyltransferase: SAVERM_RS07670 phosphatidylethanolamine 4-hydroxybenzoate in 16S rRNA in tRNA L-tryptophan polyphosphate SAVERM_RS13670 nucleoside- SAVERM_RS12600 reductase: fabG methyl parathion [apolipoprotein] carrier protein] diphosphate 16S rRNA tRNA amidase domain- tRNA phosphoribosyltransferase: 2-enyl diphosphate neopentalenoketolactone SAVERM_RS11705 predicted diphosphate kinase: ndk (2Z,4E,7E)-2- (cytosine(1402)-N(4) D-alanine--D- (guanosine(37)-N1) hydroxyisourate aromatic amino containing protein: dihydrouridine polyphosphate RS11455 UDP CMP SAVERM_RS35150 nucleoside deaminase: uridine kinase: a (3R)-3- reductase: pectate lyase: hydroxymethylglutaryl- beta-N- alpha-N- ABC (d)CMP kinase: dTTP IPP acetyl-CoA C- hydroxy-6-oxonona- diethylphosphate 4-nitrophenol apolipoprotein flavin reductase: )-methyltransferase alanine ligase: -methyltransferase hydrolase: uraH acid lyase: SAVERM_RS32145 synthase kinase 2: ppk2 a sugar a sugar adenine and SAVERM_RS24805 SAVERM_RS32215 hydroxyoctanoyl-[acp] SAVERM_RS16625 phosphotriesterase: cysteine synthase: holo-ACP synthase: SAVERM_RS32785 4-hydroxybenzoate CoA lyase: acetylhexosaminidase: arabinofuranosidase: transporter nucleoside- SAVERM_RS33535 acyltransferase: 2,4,7-triene-1,9-dioate acyltransferase: SAVERM_RS20355 RsmH: rsmH SAVERM_RS13945 TrmD: trmD (S)-2-oxo-4- SAVERM_RS18105 [+ 4 isozymes] DusB: dusB AMP adenosine salvage VI [+ 5 isozymes] uridine kinase: 3-oxoadipate SAVERM_RS07670 (2Z)-2- SAVERM_RS26650 SAVERM_RS25615 [+ 2 isozymes] octaprenyltransferase: SAVERM_RS27235 SAVERM_RS26485 SAVERM_RS29620 an N 4 - an N 1 - of a sugar diphosphate CDP dTMP 3-hydroxyacyl- SAVERM_RS07380 formate SAVERM_RS10295 [+ 3 isozymes] D-alanyl-D-alanine hydroxy-4-carboxy- serotonin a 5,6-dihydrouridine long chain SAVERM_RS17335 isopentenyl- hydroxypenta- SAVERM_RS24825 methylcytidine 1402 methylguanine 37 acetate kinase: ndk ACP dehydratase: [+ 3 isozymes] 5-ureidoimidazoline in tRNA polyphosphate gln nucleoside- dTMP kinase: tmk uridine diphosphate decanoyl-CoA 2,4-dienoate an N-acetyl-β- an α(1,5)- α-L- in 16S rRNA in tRNA Phe predicted RS19080 adenosine SAVERM_RS18860 echinomycin and triostin A biosynthesis dimethylthiophosphate 4-nitrophenol a holo-[EntB aryl- an unsaturated UTP diphosphate CMP Delta- pentalenolactone acetate a homogalacturonan + an alcohol ABC uridine kinase: an N-acyl-(S-diacyl- L-selenocysteine 3',5'-ADP pectate 4-hydroxy-3- FMN NADPH H acetoacetate acetyl-CoA D-hexosamine L-arabinan arabinofuranose a sugar a sugar kinase: ndk dTDP isomerase: idi biosynthesis acyl-CoA/acyl-ACP (2Z)-2-hydroxypenta- a 2-acyl-1-lyso- carrier protein] transporter adenosine kinase: SAVERM_RS32215 a (2E)-oct-2-enoyl-[acp] fumarate sn-glyceryl)-L- oligosaccharide octaprenylbenzoate CTP synthase: dehydrogenase: 2,4-dienoate phosphatidylethanolamine of a sugar CTP nucleoside- SAVERM_RS08020 uridine kinase: (2E,6E)-farnesyl cysteinyl-[lipoprotein] SAVERM_RS33445 enoyl-ACP ATP quinoxaline- SAVERM_RS22490 diphosphate kinase: ndk AMP SAVERM_RS17335 DMAPP diphosphate [+ 8 isozymes] RS11765 reductase pentalenene 2-carboxylate Nucleoside and Nucleotide Degradation a sugar RS38065 a sugar dTTP UMP 2503 β CTP FabI: fabI synthase: adenine a 2,3,4-saturated 4-fumaryl- N-acetyl- - (3R,6R)-1,3,4,6- a guanine 37 (2E)-dec-2-enoyl-CoA an apo [peptidyl- [EntF L-seryl- an aryl sulfate a phenol + a 1-haloalkane [+ 2 isozymes] SAVERM_RS15575 in 23S rRNA coenzyme A coenzyme A 1,2-diacyl-sn- FMN NADH H neuraminate CTP tetrachlorocyclohexa- an acyl phosphate salicyl-CoA MeOH precorrin-6B L-dopa a DNA segment 5'-deoxyadenosine carrier protein] carrier protein] acetoacetate in tRNA pentalenene purine ribonucleosides degradation pyrimidine deoxyribonucleosides degradation glycerol 3-phosphate CTP 1,4-diene tRNA bifunctional salicylyl- catalase: precorrin-6y C5,15- degradation I inosine 5'-phosphate haloalkane aromatic amino recombinase a sugar RS11005 a sugar an octanoyl-[acp] quinoxaline-2- N-acylneuraminate acylphosphatase: (guanosine(37)-N1) CoA 5-hydroxylase/ SAVERM_RS10660 methyltransferase pentalenene degradation 23S rRNA aryl-sulfate flavin reductase: haloalkane dehalogenase: acid lyase: RecA: recA RS11855 gluconeogenesis I Carbohydrate Biosynthesis carboxyl adenylate 2'-deoxycytidine holo-ACP synthase: phosphatidate fumarylacetoacetase: cytidylyltransferase: SAVERM_RS13845 -methyltransferase oxidoreductase: [+ 3 isozymes] (decarboxylating) GDP-mannose biosynthesis α Cell Structure Biosynthesis peptidoglycan maturation (meso-diaminopimelate containing) oxygenase: (S)-3- 5'-deoxyadenosine (adenine(2503)-C(2) holo-ACP synthase: sulfotransferase: SAVERM_RS20355 dehalogenase: SAVERM_RS24675 SAVERM_RS18105 UDP-N-acetyl-D- UDP- -D-glucose beta-ketoacyl- adenosine cytidylyltransferase: fahA SAVERM_RS17455 (1S,4R)-2,4,5- 1 TrmD: trmD SAVERM_RS12105 subunit CbiE: cbiE a DNA segment SAVERM_RS15580 acyl carrier protein: hydroxydecanoyl-CoA )-methyltransferase SAVERM_RS25615 SAVERM_RS25615 SAVERM_RS01595 [+ 3 isozymes] SAVERM_RS24675 an N - formaldehyde glucosamine biosynthesis I biosynthesis ACP synthase IMP a carboxylate 37 dopamine in reverse a sugar RS07100 a sugar D-glucopyranose lipid II (meso SAVERM_RS29835 S-methyl-5'- nucleoside RlmN: rlmN SAVERM_RS13660 trichloro-2,5- methylguanine gentisyl-CoA precorrin-8x (S)-malate II: fabF (S)-3- IMP orientation D-glucopyranose 6-phosphate D-glucopyranose diaminopimelate containing) methylerythritol phosphate pathway II pentalen-13-ol [+ 10 isozymes] thioadenosine adenosine deaminase: deaminase: a holo-[EntF CMP-N-acetyl- cyclohexadiene-1-diol in tRNA glucose-6- hydroxydecanoyl- dehydrogenase: a holo [peptidyl- 6-phosphate 6-phosphate [+ 2 isozymes] a quinoxaline-2- phosphorylase: SAVERM_RS06315 SAVERM_RS24805 thymidine 3',5'-ADP 3',5'-ADP an aryl sulfate a phenol + a halide anion a primary alcohol acetoacetate fumarate β-neuraminate RS20865 glucose-6- peptidoglycan 2503 L-seryl-carrier a CDP-2,3,4-saturated- FMNH NAD malate phosphate alpha-D-glucose D-glyceraldehyde pantalen-13- CoA dehydrogenase: SAVERM_RS18990 guaB [+ 4 isozymes] [+ 5 isozymes] a 2-methyladenine carrier protein] 2 phosphate glycosyltransferase: pyruvate ala carboxyl-[aryl- ser thymidine 5'-deoxyadenosine met protein] diacylglycerol predicted dehydrogenase: isomerase: pgi phosphate-specific a 3-oxodecanoyl-[acp] 3-phosphate ol oxygenase: SAVERM_RS11710 XMP in 23S rRNA isomerase: pgi rodA carrier protein] 5-deoxy-α-D- phosphorylase: ABC SAVERM_RS17775 glucose-6- phosphoglucomutase: SAVERM_RS15580 xanthosine adenosine inosine guanosine 2'-deoxyuridine thymine degradation a sugar a sugar pyruvate glucose-6- SAVERM_RS04470 a nascent peptidoglycan 3-oxoacyl-[acyl- 3-oxodecanoyl-CoA ribose 1-phosphate SAVERM_RS17405 transporter phosphate γ 1-deoxy-D-xylulose-5- pentalen-13-al quinoxaline-2- of a sugar phosphate [+ 2 isozymes] with (L-alanyl- -D-glutamyl- carrier-protein] RS14650 isomerase: pgi α-D-glucopyranose phosphate synthase: carboxyl-D-seryl-L- acetyl-CoA C- S-methyl-5- uracil phosphorylase: thymine thymine an apo-[LYS2 L- an α-D- an N 3 -methyladenine S-methyl-5- a double-stranded oxaloacetate meso-2,6-diaminopimeloyl-D- reductase: fabG + + 7,8-dihydroneopterin (2E,6E)-farnesyl isomerase: pgi F6P pantalen-13- acyltransferase: thioribose-1- tyr SAM ARP coenzyme A H hydrogencarbonate NAD(P)H a plastoquinone H 3-oxopropanoate [DNA] 4-methylcatechol thio-D-ribulose ethanol trp ser wound RNA phosphoenolpyruvate 1-phosphate alanyl-D-alanine) pentapeptide SAVERM_RS08720 alanine synthase: purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside SAVERM_RS17405 2-aminoadipyl- galactoside in DNA 2',3'-cyclic phosphate diphosphate oligonucleotide a sugar RS14665 a sugar F6P 3-oxoacyl-[acyl- al oxygenase: SAVERM_RS11705 phosphate malonic semialdehyde bifunctional DNA 1-phosphate ATP- synthase: UTP--glucose- 1-deoxy-D-xylulose-5- SAVERM_RS18800 phosphorylase: phosphorylase: phosphorylase: phosphorylase: carrier-protein] polyprenol catechol 2,3- catalase: glycogen biosynthesis III (from α-maltose 1-phosphate) bifunctional glucose-6- carrier-protein] SAVERM_RS15580 isomerase: mtnA xanthosine 5,6-dihydrothymine reductase: primase/polymerase: avermitilol synthase: methylthioribulose oligoribonuclease: tryptophan 7- L-serine dependent SAVERM_RS18195 glutamine-- 1-phosphate D-alanyl-D-alanine penicillin-binding phosphate synthase: acetyl-CoA C- SAVERM_RS17295 SAVERM_RS17295 SAVERM_RS17295 SAVERM_RS17295 NAD(P)H-quinone alpha-galactosidase: DNA-3-methyladenine phosphomannose- dioxygenase: SAVERM_RS10660 phosphate/mannose- reductase: fabG a quinoxaline-2- dihydropyrimidinase: carbonic anhydrase: SAVERM_RS03295 SAVERM_RS27045 SAVERM_RS00815 1-phosphate orn halogenase: ammonia-lyase: RNA helicase fructose-6- uridylyltransferase carboxypeptidase/ protein 2: SAVERM_RS11760 acyltransferase: S-methyl-5- bifunctional FO holo-ACP synthase: dehydrogenase: SAVERM_RS37320 glycosylase I: dependent alpha 1,6 SAVERM_RS08560 [+ 3 isozymes] RS14730 D-glucopyranose 6-phosphate 1-deoxypentalenate carboxyl-D-seryl-L- hydA SAVERM_RS29185 [+ 8 isozymes] (2Z,4E)-2-hydroxy- dehydratase: mtnB SAVERM_RS09215 SAVERM_RS14450 HrpA: hrpA a sugar RS07440 a sugar phosphate ADP-α-D-glucose GalU: galU D-alanyl-D-alanine- SAVERM_RS15350 a mature peptidoglycan with a (3R)-3- SAVERM_RS07380 thioribose-1- purine-nucleoside 2-deoxy-α- biosynthesis protein SAVERM_RS25615 SAVERM_RS17285 [+ 3 isozymes] SAVERM_RS16180 malonic semialdehyde mannosyltransferase a 2'- 5-(methylsulfanyl) a nucleoside 5'- phosphoenolpyruvate 6-phosphate isomerase: cys alanyl-[non-ribosomal val α-D-ribose-1-phosphate uracil [+ 3 isozymes] 5-methyl-6-oxohexa- avermitilol acetaldehyde 7-chloro-L- transaminase endopeptidase: dacB [+ 3 isozymes] (L-alanyl-γ-D-glutamyl-meso- hydroxydecanoyl-[acp] 1-deoxy-D-xylulose 1-deoxypentalenic phosphate phosphorylase: D-ribose 1- 3-(carbamoylamino)- CofGH: SAVERM_RS19605 reductase: MptB: mptB deoxyribonucleoside -2,3-dioxopentyl monophosphate pyruvate an unwound RNA SAVERM_RS26035 α peptide synthase] octanoyl-CoA 7,8-dihydroneopterin 2,4-dienoate tryptophan (isomerizing) UDP- -D-glucose 2,6-diaminopimeloyl-D-alanyl- 3-hydroxyacyl- 5-phosphate acid 11-beta- isomerase: mtnA SAVERM_RS17295 α-D-ribose 1,5- phosphate 2-methylpropanoate a holo-[LYS2 L- α a non SAVERM_RS16640 5'-monophosphate 1-phosphate phosphopyruvate penicillin-binding -D- an apurinic site 2'-phosphate mannose-6- a nascent peptidoglycan hydroxylase: ptlH + 3-hydroxypropanoate a sugar RS07515 a sugar hydratase: eno : glmS protein 2: mrdA D-alanine) pentapeptide ACP dehydratase: 1-deoxy-D-xylulose- acyl-CoA/acyl-ACP 5-deoxy-D-ribulose xanthine phosphomutase: β-ureidopropionase: 5-amino-5-(4-hydroxybenzyl)-6- 3',5'-ADP 2-aminoadipyl- CO H O a plastoquinol NAD(P) galactopyranose galactosylated 3-methyladenine phosphate with D,D cross-links (meso- β 5'-deoxyadenosine 2-iminoacetate 2 2 within DNA RS21930 glutamine-- SAVERM_RS18860 5-phosphate 1-deoxy-11 - dehydrogenase: 1-phosphate SAVERM_RS17300 SAVERM_RS10280 (D-ribitylimino)-5,6-dihydrouracil met carrier-protein] galactose acceptor trehalose-6- isomerase, a nascent peptidoglycan diaminopimelate containing) purine deoxyribonucleosides degradation I 2-phospho-D-glycerate fructose-6- reductoisomerase: hydroxypentalenate SAVERM_RS22490 phosphate synthase: class I: manA with (L-alanyl-γ-D-glutamyl- a (2E)-dec-2-enoyl-[acp] pyrimidine deoxyribonucleotides D-ribose 5-phosphate (R)-3-amino-2- phosphate SAVERM_RS13370 1-deoxy-11-beta- triostin A dithiol [+ 8 isozymes] a sugar RS12340 a sugar SAVERM_RS20310 D-mannopyranose meso-2,6-diaminopimeloyl- dephosphorylation adenosine deaminase: methylpropanoate transaminase hydroxypentalenate UDP-N-acetyl- decaprenyl-diphospho-N- p-nitrophenyl-α-D- α-D- a plant 6-phosphate nucleoside triphosphate 7,8-dihydrofolate + a 1,2-diacyl- an (S)-2- 7,8-dihydro- D-alanine) tetrapeptide a mature peptidoglycan enoyl-ACP MEP (2E)-oct-2-enoyl-CoA urate SAVERM_RS06315 2'-deoxyadenosine α coenzyme A an apo-[aryl- NADPH H CDP-choline 7,8-dihydroneopterin 4-nitrocatecholsulfate a folate CAIR RS14870 (isomerizing) dehydrogenase: ptlF pyrophosphohydrolase: -D-glucosamine acetylmuramoyl-pentapeptide monoglutamate sn-glycerol halocarboxylate galactopyranoside glucopyranose cys arabinogalactan thr 8-oxoguanine trp cys alpha-D-glucose phosphomannomutase/ with D,D cross-links (meso- reductase acetaldehyde DHAP [+ 4 isozymes] carrier protein] 2',3'-cyclic phosphate : glmS 1-deoxy-11- SAVERM_RS18275 1-phosphate dTTP polyprenol sulfatase: dihydrofolate type I 8-oxoguanine 5-(carboxyamino) a sugar RS15690 a sugar 3-phospho-D-glycerate phosphate-specific phosphoglucomutase: L,D-transpeptidase: L,D-transpeptidase: diaminopimelate containing) FabI: fabI 2-C-methyl-D- arabinogalactan threonine aromatic amino cystathionine D-glucosamine oxopentalenate dCTP dCMP undecaprenyldiphospho- phosphomannose- cysteine dioxygenase: SAVERM_RS29150 reductase: deaminase: imidazole phosphoglucomutase: α α SAVERM_RS26030 SAVERM_RS25625 SAVERM_RS25625 [+ 2 isozymes] erythritol 4-phosphate triostin A dihydrofolate chloramphenicol HAD family hydrolase: alpha-galactosidase: endo-1,4-beta- ammonia-lyase: acid lyase: gamma-lyase: phosphoglycerate 6-phosphate , -trehalose 1-deoxy-11- 2'-deoxyinosine 2'-deoxyguanosine S-methyl-5'- pseudouridine muramoylpentapeptide beta-N- glucose-1-phosphate dependent alpha 1,6 SAVERM_RS12975 sulfatase: SAVERM_RS16795 SAVERM_RS10615 ribonucleotide SAVERM_RS04470 α-D-mannose [+ 3 isozymes] a nascent peptidoglycan with [+ 3 isozymes] a mature peptidoglycan cytidylyltransferase: (S)-3- holo-ACP synthase: reductase: phosphotransferase SAVERM_RS24410 SAVERM_RS37320 galactosidase: SAVERM_RS17090 SAVERM_RS18105 SAVERM_RS22095 kinase: 6-phosphate γ γ oxopentalenate thioadenosine degradation acetylglucosaminyltransferase: thymidylyltransferase mannosyltransferase SAVERM_RS41430 mutase: purE phosphoglucosamine [+ 2 isozymes] 1-phosphate (L-alanyl- -D-glutamyl-meso- with (L-alanyl- -D-glutamyl- a decanoyl-[acyl-carrier protein] SAVERM_RS20485 dUTP diphosphatase: dut purine-nucleoside SAVERM_RS25615 SAVERM_RS16795 CPT: cpt [+ 10 isozymes] [+ 3 isozymes] SAVERM_RS07085 a sugar RS32455 a sugar RS12025 SAVERM_RS32395 trehalose- a nascent peptidoglycan a nascent peptidoglycan oxygenase: hydroxyoctanoyl-CoA degradation I murG RfbA: rfbA MptB: mptB 4-nitrocatechol a 7,8-dihydrofolate 2-oxobutanoate urate tryptamine pyruvate AIR mutase: 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- 4-(cytidine 5'- S-methyl-5'- nucleoside triphosphate phosphorylase: 3-sulfino-L-alanine a galactotetraose SAVERM_RS25590 phosphatase: with L,D cross links (meso- with (L-alanyl-γ-D-glutamyl- D-alanine) tetrapeptide beta-ketoacyl- diphospho)-2-C- SAVERM_RS15560 enoyl-CoA pyrophosphohydrolase: purine-nucleoside SAVERM_RS17295 purine-nucleoside S-methyl-5'- pseudouridine 7,8-dihydroneopterin 13-DPG thioadenosine CMP α otsB diaminopimelate containing) meso-2,6-diaminopimeloyl- ACP synthase echinomycin hydratase/isomerase phosphorylase: phosphorylase: thioadenosine a holo-[aryl- 5,6,7,8- + a (2R)-2- D-galactopyranose 4-nitrophenol 3'-phosphate -D-glucosamine methyl-D-erythritol pentalenolactone D degradation II SAVERM_RS18275 decaprenyl-pyrophosphoryl- UDP 3',5'-ADP NADP a phosphatidylcholine a halide anion dTDP-α-D-glucose glycine) tetrapeptide II: fabF 4-(cytidine 5'- family protein: dUTP dUMP SAVERM_RS17295 SAVERM_RS17295 carrier protein] tetrahydrofolate hydroxy fatty acid a sugar RS26290 a sugar type I glyceraldehyde- 1-phosphate α,α-trehalose GDP-α-D-mannose glycogen biosynthesis I (from ADP-D-Glucose) a mature peptidoglycan with S-methyl-5'- (N-acetylglucosamine)-N- diphospho)- SAVERM_RS11710 pseudouridine RS23115 3-phosphate bifunctional UDP-N- (L-alanyl-γ-D-glutamyl-meso- [+ 2 isozymes] pentalenolactone thioadenosine MTR acetylmuramyl-(pentapeptide) 2-C-methyl-D- S-methyl-5'- α 5'-phosphate dehydrogenase: gap acetylglucosamine maltose alpha-D- D-glucopyranose a mature peptidoglycan 2,6-diaminopimelate) tripeptide D dioxygenase: 3-oxooctanoyl-CoA 2-deoxy- -D-ribose 1-phosphate glucosyltransferase: 6-phosphate a 3-oxododecanoyl-[acp] erythritol kinase: thioadenosine 5-hydroxy-CTP 5-hydroxy-CMP S-methyl-5- diphosphorylase/ with L,D cross-links (meso- a mature peptidoglycan SAVERM_RS15565 pseudouridine- a [glycine-cleavage p-nitrophenyl- a supercoiled 6-O-cis-keto- a sugar RS26475 a sugar type I glyceraldehyde- phosphorylase: D-glucopyranose maltopentaose + an (R)-2- a [protein] (L-serine/L- treS alpha-D-glucose diaminopimelate containing) with (L-alanyl-γ-D-glutamyl- SAVERM_RS18525 acetyl-CoA C- thioribose 5'-phosphate complex H protein] coenzyme A AsbD acyl- phylloquinone NAD(P)H H β raffinose a [protein] Ser/Thr N-ethylmaleimide a chitodextrin L-homoserine methylglyoxal tyr thr mycolyl-trehalose triose-phosphate 3-phosphate glucosamine-1- α-D- 3-oxoacyl-[acyl- 2-phospho-4-(cytidine pentalenolactone E SAVERM_RS18990 a sulfurated [sulfur carrier] SAM halocarboxylate -D-galactoside threonine) phosphate duplex DNA maltose alpha-D- phosphate-specific meso-2,6-diaminopimeloyl- acyltransferase: kinase: glycosidase: N 6 -octanoyl-L-lysine carrier protein serine/threonine UvrD-helicase domain- chitinase: 6-phosphate RS23370 isomerase: dehydrogenase: gap phosphate N- glucopyranose carrier-protein] 5'-diphospho)-2-C- 5-MTR-1-P protein phosphatase glyoxalase: ADP-α-D-glucose glucosyltransferase: phosphoglucomutase: glycine) tetrapeptide SAVERM_RS11705 mtnK SAVERM_RS32245 protein kinase: containing protein: alkene reductase: SAVERM_RS24910 cystathionine aromatic amino L-threonine 3- trehalose- SAVERM_RS32400 acetyltransferase 1-phosphate reductase: fabG methyl-D-erythritol pentalenolactone 4-alpha- NAD(P)H-quinone beta-glucosidase: alpha-galactosidase: 2C domain- SAVERM_RS04145 a sugar RS13435 a sugar DHAP D-glyceraldehyde 3-phosphate GlmU: glmU treS SAVERM_RS04470 E dioxygenase: acetyl-CoA C- HAD family hydrolase: SAVERM_RS24885 SAVERM_RS26440 SAVERM_RS20690 chitinase: gamma-lyase: acid lyase: dehydrogenase: phosphatase: 3-oxoacyl-[acyl- 2-C-methyl-D- 5-MTR-1-P uracil lipoyl holo-ACP synthase: glucanotransferase: dehydrogenase: SAVERM_RS24410 SAVERM_RS09500 SAVERM_RS37320 containing protein: SAVERM_RS22095 [+ 2 isozymes] SAVERM_RS18105 tdh otsB α α [+ 2 isozymes] SAVERM_RS15565 acyltransferase: [+ 19 isozymes] [+ 6 isozymes] SAVERM_RS29080 N-acetyl- -D- -maltose-1- α-maltose erythritol 2,4- SAVERM_RS25615 malQ SAVERM_RS17285 [+ 2 isozymes] [+ 3 isozymes] SAVERM_RS27745 N,N'- trehalose-cis-keto- α-D- carrier-protein] SAVERM_RS07380 synthase: lipA [+ 9 isozymes] a [protein] (L-serine/L- a single N-ethylsuccinimide 2-oxobutanoate (R)-lactate p-tyramine aminoacetone glucosamine phosphate cyclodiphosphate [+ 3 isozymes] diacetylchitobiose mono-mycolate glucopyranose reductase: fabG pro pentalenolactone F threonine) phosphate stranded DNA a sugar RS27125 a sugar RS23600 1-phosphate synthase: synthase: hexanoyl-CoA α-D- a [protein] Ser/Thr class II fructose- maltokinase: 1-phosphate a (3R)-3- Amino Acid Degradation a [glycine-cleavage a holo-[AsbD acyl- maltose maltotetraose a (2R)-2- D-galactopyranose sucrose bifunctional UDP-N- glgA SAVERM_RS20480 3',5'-ADP NAD(P) + phylloquinol a halide anion 4-nitrophenol galactopyranose bisphosphate SAVERM_RS37970 5'-deoxyadenosine 6 an unsulfurated acetylglucosamine glucose-1-phosphate Metabolic Regulator Biosynthesis hydroxydodecanoyl-[acp] acyl-CoA/acyl-ACP met complex H protein] N carrier protein] hydroxy fatty acid aldolase: fbaA adenylyltransferase: 2-C-methyl-D-erythritol- L-valine degradation I -[(R)-lipoyl]-L-lysine [sulfur carrier] diphosphorylase/ α 3-hydroxyacyl- preQ biosynthesis dehydrogenase: L-isoleucine degradation I L-arginine degradation a sugar RS27460 a sugar PRPP biosynthesis -maltose 1- 2,4-cyclodiphosphate 0 L-arginine degradation V L-glutamate degradation L-histidine degradation I glucosamine-1- glgC ppGpp metabolism ACP dehydratase: SAVERM_RS22490 RS24125 phosphate mannosylglucosylglycerate trehalose biosynthesis V trehalose biosynthesis II an L-prolyl-[RedO pentalenolactone XIII (reductive (arginine deiminase pathway) VI (to pyruvate) a (1->4)- trehalose biosynthesis IV flavodoxin- [+ 8 isozymes] α D-ribose 5- phosphate N- ADP-α-D-glucose SAVERM_RS18860 prolyl-carrier protein] val Stickland reaction) XLXG xyloglucan β-D-glucose 6-O- -mycolyl- alpha-1,4-glucan-- α-D-glucan biosynthesis I dependent ile methylmalonate semialdehyde Reactive Blue 5 D-glucopyranose maltohexaose a β-D-galactoside D-threo-7,8- melibionate cellulose hydantoin a cytosine in DNA an N-hydroxy- cyanophycin chitosan (2S)- β-D-fructose 1,6-bisphosphate phosphate acetyltransferase pppGpp D-glucopyranose GTP his oligosaccharide phe 6-phosphate trehalose 6- a sugar RS27785 a sugar ribose-phosphate maltose-1-phosphate α glycogen a glycogen α α (2E)-hexenoyl-CoA arg glu dihydroneopterin arylamine ethylmalonyl-CoA GlmU: glmU UDP- -D-galactose bifunctional (p)ppGpp 3-phospho- ADP- -D-glucose 6-phosphate -maltose a (2E)-dodec-2-enoyl-[acp] (E)-4-hydroxy- GTP arg histidine endo-1,4-beta-glucanase: inositol-3-phosphate chitosanase: phosphate pyrophosphokinase: maltosyltransferase: synthase: UDP-α-D-glucose glycogen branched-chain DNA cytosine arylamine N- methylmalonyl- class II fructose- UDP-N-acetyl- biosynthesis synthetase/guanosine- D-glycerate maltose alpha-D- 3-methylbut- cyclohydrolase branched-chain arginine deiminase: ammonia- SAVERM_RS13395 dihydropyrimidinase: aromatic amino synthase: cyanophycinase: SAVERM_RS31865 trehalose- SAVERM_RS38245 SAVERM_RS37960 glgA debranching protein: enoyl-ACP amino acid CoA-acylating 4-alpha- beta-glucosidase: beta-glucosidase: alpha-galactosidase: methyltransferase: acetyltransferase: CoA RS24160 bisphosphatase: glpX α-D-glucosamine 3',5'-bis(diphosphate) 3'- trehalose-6- glucosyltransferase: treS a 1H-pyrrole-2-carbonyl- 2-enyl- 7,8- I FolE: folE amino acid SAVERM_RS12130 arginine deiminase: lyase: hutH Dyp-type peroxidase: dihydroneopterin endo-1,4-beta-glucanase: hydA acid lyase: SAVERM_RS22210 SAVERM_RS17150 chitosanase: phosphatase: ribose-phosphate a (1->4)- UDP-α-D-glucose a (1->4)- SAVERM_RS07760 reductase [RedO prolyl-carrier protein] diphosphate dihydroneopterin aminotransferase: aminotransferase: methylmalonate- glucanotransferase: SAVERM_RS09500 SAVERM_RS09500 SAVERM_RS37320 SAVERM_RS18105 SAVERM_RS28575 SAVERM_RS28680 epimerase: mce otsB a sugar RS13830 a sugar pyrophosphohydrolase: glucosyl-3- phosphate synthase: maltose alpha-D- malonyl-CoA SAVERM_RS12130 urocanate SAVERM_RS18590 aldolase: folB SAVERM_RS13425 β SAVERM_RS10605 diphosphokinase: α-D-glucan α-D-glucan [+ 3 isozymes] FabI: fabI SAVERM_RS04665 L-citrulline semialdehyde malQ [+ 2 isozymes] [+ 2 isozymes] [+ 3 isozymes] a 5-methylcytosine an N- N- -aspartyl- a chitosan (2R)- α, α'-trehalose F6P UDP-glucose SAVERM_RS35155 phosphoglycerate SAVERM_RS20310 glucosyltransferase: treS synthase: ispG 3'-triphosphate (S)-3- SAVERM_RS04665 a cellodextrin N-carbamoylglycine 2-phenylethylamine Ins(3)P SAVERM_RS18405 a maltodextrin glucosylglycerate α α branched-chain (2S, 3S)-3- dehydrogenase: mmsA in DNA acetoxyarylamine L-arginine fragment ethylmalonyl-CoA 6-α-mycolate 1,4-alpha- 4-epimerase 1,4-alpha- guanosine 3'- synthase: , -trehalose [+ 2 isozymes] flavodoxin- 6-carboxytetrahydropterin hydroxyhexanoyl-CoA branched-chain ornithine L-citrulline urocanate hydratase: glucose-6-phosphate PRPP bifunctional (p)ppGpp biosynthesis I amino acid methylaspartate 3-[(4-amino-6-chloro- XXXG xyloglucan α-D- glucan GalE: galE glucan diphosphate 5'- SAVERM_RS20305 malto- α,α-trehalose dependent synthase: 3-hydroxyhexanoyl- amino acid carbamoyltransferase: SAVERM_RS18065 2,2'-disulfonyl maltopentaose maltose D-galactopyranose a non galactosylated D-galactopyranose 6-(hydroxymethyl) glycolaldehyde D-gluconate RS24815 isomerase: pgi synthetase/guanosine- a dodecanoyl-[acp] a [RedX acyl-carrier aminotransferase: L-threonine degradation I 1,3,5-triazin-2-yl) phthalate oligosaccharide galactopyranose branching [+ 3 isozymes] branching triphosphate 3'- oligosyltrehalose 3-phospho- 6-phosphate (E)-4-hydroxy- SAVERM_RS09475 CoA dehydrogenase: aminotransferase: SAVERM_RS18795 4-imidazolone- azobenzene galactose acceptor -7,8-dihydropterin UDP-α-D-galactose 3',5'-bis(diphosphate) 3'- α α malonyl-CoA protein]-(1H-pyrrole- a malonyl-[RedN] SAVERM_RS14165 hydrogencarbonate NADH propanoyl-CoA H + amino]benzenesulfonate glucose-6-phosphate enzyme: enzyme: diphosphatase: 2-O-( -D- synthase: treY D-glycerate GDP- -D-glucose 6-carboxy-5,6,7,8- SAVERM_RS08890 SAVERM_RS14165 ornithine pyrophosphohydrolase: trehalose- 2-carbonyl)-L-cysteine 3-methylbut- ornithine 5-propanoate isomerase: pgi glgB glgB SAVERM_RS35155 glucopyranosyl) tetrahydropterin 3-hydroxyacyl-CoA 3-methyl-2- carbamoyltransferase: α a maltooligosyl- phosphatase: 2-enyl- (3S)-3-methyl-2- carbamoyltransferase: thr imidazolonepropionase: SAVERM_RS12890 -3-phospho- GDP- -D- oxobutanoate SAVERM_RS18795 mesaconate D-glucopyranose 6-phosphate a GlgE-glycogen a glycogen trehalose glucosyl-3- otsB diphosphate dehydrogenase: oxopentanoate argF threonine SAVERM_RS18050 D-glycerate mannose a [pyruvate dehydrogenase E2 a [mycoredoxin]- mycothiol- a 1-O-(alk-1-enyl)-sn-glycero- XXLG xyloglucan adenine 1518 / an insertion sequence 3-amino-4- (2R,3S)-3- (2R,3S)-3- RS12425 phosphoglycerate synthase: ispG SAVERM_RS11710 ornithine ammonia-lyase: D-glucopyranose a maltodextrin stachyose uroporphyrinogen-III oxaloacetate androstenedione acetoacetate homogentisate Fe 2+ malto- a dodecanoyl-[RedQ 6 1519 synthase: α,α-trehalose a malonyl-[RedL (E)-4-hydroxy-3- L-ornithine carbamoyltransferase: N-formimino- a sulfurated [sulfur carrier] SAM protein] N -octanoyl-L-lysine L-cysteine arsenate conjugate 3-phosphoethanolamine oligosaccharide adenine in 16S rRNA element IS30 hydroxybenzaldehyde isopropylmalate isopropylmalate oligosyltrehalose acyl-carrier protein] a 3-oxo-3-(1H-pyrrol- (2Z)-2-aminobut-SAVERM_RS17090 16S rRNA SAVERM_RS20305 polyketide synthase] methylbut-2-en- 7-carboxy-7- 3-oxohexanoyl-CoA argF L-glutamate transposase: arylamine N- phosphoenolpyruvate 3-oxosteroid 1- 3-isopropylmalate acetoacetate 3-isopropylmalate homogentisate trehalohydrolase: 2-yl)propanoyl-[RedN] 2-enoate (adenine(1518)-N(6)/ uroporphyrinogen 1-yl diphosphate deazaguanine isobutanoyl-CoA (2S)-2- ornithine- 4-alpha- beta-glucosidase: alpha-galactosidase: SAVERM_RS43520 acetyltransferase: carboxykinase (GTP) dehydrogenase: dehydrogenase: decarboxylase: dehydratase: 1,2-dioxygenase: bacterioferritin: bfr GTP ppGpp 2-[2-O-(α-D- treZ 2-O-(α-D- acetyl-CoA (S)-citramalate mycoredoxin: lysoplasmalogenase: adenine(1519)-N(6))- decarboxylase: hemE methylbutanoyl-CoA -oxo-acid carbamoyl glucanotransferase: SAVERM_RS09500 SAVERM_RS37320 [+ 15 isozymes] SAVERM_RS28680 : SAVERM_RS17015 SAVERM_RS08450 SAVERM_RS14170 SAVERM_RS07215 leuD leuC hmgA mannopyranosyl) glucopyranosyl) acetyltransferase: lipoyl synthase: lipA SAVERM_RS15955 SAVERM_RS33145 dimethyltransferase an insertion RS25315 α,α-trehalose trehalose biosynthesis I transaminase: L-ornithine malQ [+ 2 isozymes] [+ 3 isozymes] 3-acetylamino-4- phosphoenol androsta-1,4- 4-methyl-2- (2S)-2- 4-maleyl- 3+ -(1->2)-α-D- 1-hydroxy-2- SAVERM_RS09000 phosphate RsmA: rsmA coproporphyrinogen III sequence IS30 with acetone Fe -3-phospho- a 3-oxotetradecanoyl- 4-hydroxy-2,2'- rocD citramalate synthase: N 6 -dimethyladenine 1518 hydroxybenzaldehyde pyruvate diene-3,17-dione oxopentanoate isopropylmalate acetoacetate glucopyranosyl]- [+ 6 isozymes] integrated transposon D-glycerate D-glucopyranose methyl-2-butenyl preQ glutamine- 2-iminobutanoate glu a [mycoredoxin] α 6 1519 UDP-α-D-glucose [RedL polyketide synthase] bipyrrole-5-methanol 0 ornithine- SAVERM_RS14130 sn-glycero-3- XXXG xyloglucan -D- /N -dimethyladenine nucleoside- 3-phospho- 6-phosphate 4-diphosphate methylacrylyl-CoA (E)-2- hydrolyzing a [pyruvate dehydrogenase arsenite mycothiolyl-S-S- a maltodextrin maltose a fatty aldehyde D-galactopyranose raffinose bifunctional (p)ppGpp geosmin biosynthesis butanoyl-CoA -oxo-acid 5'-deoxyadenosine phosphoethanolamine oligosaccharide galactopyranose in 16S rRNA diphosphate D-glycerate reductase: methylcrotonoyl-CoA carbamoyl- met 6 an unsulfurated [sulfur carrier] synthetase/guanosine- transaminase: E2 protein] N -lipoyl-L-lysine L-cysteine disulfide RS12490 kinase: ndk GDP trehalose-6- SAVERM_RS08735 phosphate acetate pyruvate 3',5'-bis(diphosphate) 3'- 2-O-(α-D- 1-hydroxy-2- (2E,6E)-farnesyl acyl-CoA/acyl-ACP rocD pyrophosphokinase: phosphate synthase: 5-undecyl-1,2- 4-hydroxy-2,2'- synthase: pyrophosphohydrolase: glucopyranosyl) methyl-2-butenyl 4-hydroxy-3-methylbut- diphosphate dehydrogenase: SAVERM_RS35155 SAVERM_RS20310 dihydropyrrol-3-one bipyrrole-5-carbaldehyde germacradienol/ L-glutamate-5- carA carB 2-oxobutanoate 2-[2-O-(α-D- -D-glycerate 4-diphosphate 2-enyl diphosphate SAVERM_RS22490 (S)-3-hydroxy- glycine cleavage a plant soluble a long-linear 55 SAVERM_RS35155 (2S,3S)-3-hydroxy-2- UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N a 2-deoxy-D- XLLG xyloglucan α a uridine 3-amino-4- cholest-4- a supercoiled uridine mannopyranosyl) reductase: reductase: geosmin synthase: [+ 8 isozymes] isobutanoyl-CoA semialdehyde γ a nucleobase D-glucopyranose heteroglycan fumarate -D-glucopyranose α-D-glucan a reduced factor 420 uroporphyrinogen-I 2-hydroxyisobutyramide 15-cis-phytoene an arylamine citrate bifunctional (p)ppGpp α α methylbutanoyl-CoA carbamate -acetylmuramoyl-L-alanyl- - ribosyl-base asp oligosaccharide in tRNA hydroxybenzoate en-3-one duplex DNA -(1->2)-α-D- , -trehalose SAVERM_RS08735 SAVERM_RS16625 (1E,4S,5E,7R)-SAVERM_RS11355 a [glycine-cleavage NADPH-dependent amidase domain- uridine kinase: RS15870 6 D-glutamyl-L-lysyl- D-alanine tRNA arylamine N- arylamine N- 3-oxosteroid 1- DNA helicase aconitate synthetase/guanosine- 6-phosphate germacra-1(10) crotonyl-CoA complex H protein] N glycine cleavage system uroporphyrinogen phytoene desaturase: SAVERM_RS32215 glucopyranosyl]- 4-hydroxy-3-methylbut- undecaprenyldiphospho- 4-alpha- 4-alpha- F420 reductase: npdG containing protein: pseudouridine(55) acetyltransferase: acetyltransferase: dehydrogenase: RecQ: recQ hydratase 3',5'-bis(diphosphate) 3'- trehalose- 4-methoxy-2,2'- ,5-dien-11-ol -[(R)-lipoyl]-L-lysine aminomethyltransferase nucleoside 2- beta-glucosidase: decarboxylase: hemE SAVERM_RS05605 uridine kinase: D-glycerate 2-undecylpyrrole 2-enyl diphosphate propanoyl-CoA muramoylpentapeptide beta-N- glucanotransferase: L-aspartate oxidase: glucanotransferase: NADPH-dependent SAVERM_RS32145 synthase TruB: truB SAVERM_RS28680 SAVERM_RS28680 SAVERM_RS08450 AcnA: acnA pyrophosphohydrolase: phosphatase: bipyrrole-5-carbaldehyde germacradienol/ (S)-3-hydroxy- (S)-1-pyrroline- GcvT: gcvT deoxyribosyltransferase: SAVERM_RS09500 [+ 3 isozymes] SAVERM_RS17335 reductase: IPP acetylglucosaminyltransferase: malQ SAVERM_RS24200 malQ F420 reductase: [+ 4 isozymes] 55 SAVERM_RS12890 otsB geosmin synthase: isobutanoate 2-methylacetoacetyl-CoA 5-carboxylate glycine cleavage system SAVERM_RS43800 [+ 2 isozymes] coproporphyrinogen I 2-hydroxy-2- 9,15,9'-tri-cis a pseudouridine 3-acetylamino-4- an N- cholesta-1,4- a single stranded DNA UMP D-threo-isocitrate SAVERM_RS16625 CO phosphate aminomethyl- SAVERM_RS04030 ζ GDP SAVERM_RS11355 2 aminomethyltransferase murG - -carotene in tRNA hydroxybenzoate acetylarylamine dien-3-one RS08385 (S)-3- pyrroline-5- propionyltransferase: pta transferring methylpropanoate α,α-trehalose (8S,9S,10S)- GcvT: gcvT a plant soluble XXXG xyloglucan a short 1,4- an oxidized factor 420 isopentenyl- hydroxybutanoyl-CoA acetyl-CoA C- carboxylate glycine a 2-deoxy-D- maltose 8,10-dimethyl- propanoyl ditrans,octacis-undecaprenyldiphospho- UDP a nucleobase heteroglycan 2-iminosuccinate succinate oligosaccharide D-galactopyranose α-D-glucan diphosphate (S)-3-hydroxybutanoyl- acyltransferase: reductase: [+ 2 isozymes] dehydrogenase: ribosyl-base undecylprodigiosin 1-octalin (S)-methylmalonate- phosphate N-acetyl-(N-acetylglucosaminyl)muramoyl- Delta- germacradienol/ CoA dehydrogeanse: SAVERM_RS07380 proC gcvP L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine semialdehyde a [glycine-cleavage isomerase: idi geosmin synthase: SAVERM_RS08890 acetyl-CoA C- L-tryptophan acetate kinase: a [glycine-cleavage RS26275 pro degradation I complex H protein] N 6 - SAVERM_RS11355 3-hydroxyacyl-CoA acyltransferase: SAVERM_RS14690 complex H protein] N 6 CoA-acylating (via anthranilate) aminomethyldihydrolipoyl- UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- a 1-arachidonoyl- an [amino-group carrier protein]- 2-hydroxychromene- (1S,4R)-2,4,5-trichloro- a cytosine 967 (R)-3- γ-glutamyl- (S)-2- cytidine a double dehydrogenase: methylmalonate- SAVERM_RS11705 -dihydrolipoyl-L-lysine alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine CDP-choline D-glucopyranose maltotetraose a sialyloligosaccharide maltotriose a glucan C-terminal-γ-(L-glutamate 5- 4-guanidinobutyramide D-glucopyranose ferroheme o streptorubin B DMAPP (-)-geosmin propanoate L-lysine 2-acyl-sn-glycerol 2-carboxylate 2,5-cyclohexadiene-1-diol in 16S rRNA hydroxybutanoate isopropylamide hydroxyglutarate uridine kinase: stranded DNA SAVERM_RS11710 semialdehyde semialdehyde-2-yl)-L-glutamate 2-hydroxychromene- amidase domain- glucose 1- (S)-3-amino-2- trp undecaprenyldiphospho- N-acetyl-gamma- haloalkane rRNA cytosine-C5- 3-hydroxybutyrate ferredoxin: L-2- SAVERM_RS32215 dehydrogenase: tryptophan 2,3- 2-carboxylate containing protein: dehydrogenase: heme A synthase: DNA: acetoacetyl-CoA methylpropanoate acetyl-CoA propanoyl-CoA muramoylpentapeptide beta-N- chloramphenicol 4-alpha- exo-alpha-sialidase: 4-alpha- glutamyl-phosphate dehalogenase: methyltransferase: dehydrogenase: SAVERM_RS28325 hydroxyglutarate uridine kinase: RS16095 mmsA dioxygenase: L-cysteine degradation II isomerase: SAVERM_RS32145 SAVERM_RS19640 SAVERM_RS32510 gyrB gyrA acetylglucosaminyltransferase: phosphotransferase glucanotransferase: SAVERM_RS28930 glucanotransferase: reductase: SAVERM_RS24675 SAVERM_RS35350 SAVERM_RS07565 [+ 6 isozymes] oxidase: lhgO SAVERM_RS17335 acetyl-CoA C- SAVERM_RS23380 malQ malQ SAVERM_RS34730 SAVERM_RS18850 [+ 4 isozymes] 967 D-glucono- γ N-Formyl-L- glycine cleavage system L-serine degradation murG CPT: cpt [+ 3 isozymes] an [amino-group carrier protein]- trans-O- (1S,4S)-2,5-dichloro-2,5- a 5-methylcytosine acetoacetate N-( -L-glutamyl) ferroheme a 2-oxoglutarate CMP a negatively acyltransferase: propanoyl-CoA kynurenine aminomethyltransferase C-terminal-γ-(5-phospho- cyclohexadiene-1,4-diol 4-guanidinobutanoate in 16S rRNA 1,5-lactone -L-alaninol supercoiled DNA SAVERM_RS07380 cys hydroxybenzylidenepyruvate cystathionine GcvT: gcvT L-glutamyl)-L-glutamate L-threonine ser ditrans,octacis-undecaprenyldiphospho-N- UDP a 1-arachidonoyl-2-acyl-sn CMP maltose maltotriose N-acetylneuraminate an oligosaccharide a glucan D-glucopyranose RS03965 [+ 6 isozymes] L-arginine gamma-lyase: β degradation II L-glutamate L-serine acetyl-(N-acetyl- -D-glucosaminyl)muramoyl-L- -glycero-3-phosphocholine degradation γ acetyl-CoA degradation II 2-aminoprop-SAVERM_RS22095 ammonia-lyase: alanyl- -D-glutamyl-L-lysyl-D-alanyl-D-alanine III (arginine L-kynurenine L-glutamine thr 2-enoate L-glutamate 2-aminoprop-SAVERM_RS14450 decarboxylase/ α degradation I L-threonine 3- glu degradation I 2-enoate 5-amino-4- 6-[1-hydroxyethyl]-7- 4a-hydroxy-L- a 2-O-( -D-mannosyl)-1- 3-(4- 25-hydroxycholest- an organic dCTP agmatinase pathway) dethiobiotin a sulfurated PRPP isomaltose β-lindane protoporphyrinogen IX an aliphatic amine D-glucopyranose L-idonate (R)-lactate D-glucopyranose RS16315 dehydrogenase: arg kynureninase: aspartate SAM imidazolecarboxyamide methyl-7,8-dihydropterin erythro-5,6,7,8- phosphatidyl-1D-myo-inositol hydroxyphenyl) 4-en-3-one hydroperoxide [sulfur carrier] phosphatidylinositol gln tdh kynU transaminase: 2-amino-4-hydroxy-6- tetrahydrobiopterin pyruvate haloalkane 3-oxosteroid 1- copper amine glucose 1- alkyl hydroperoxide L-idonate 5- D-2-hydroxyacid dCTP deaminase: xylose L-2-amino-3- glu 4a-hydroxytetrahydrobiopterin mannoside protoporphyrinogen imidazole SAVERM_RS25330 2-iminopropanoate hydroxymethyldihydropteridine 4-hydroxyphenylpyruvate dehalogenase: dehydrogenase: oxidase: dehydrogenase: reductase: dehydrogenase: dehydrogenase: SAVERM_RS23060 isomerase: oxobutanoate NAD-glutamate adenine dehydratase: oligo-1,6-glucosidase: acyltransferase: oxidase: hemG glycerol anthranilate asp biotin diphosphokinase: folK dioxygenase: hppD SAVERM_RS24675 SAVERM_RS08450 SAVERM_RS11280 SAVERM_RS19640 SAVERM_RS16740 SAVERM_RS34045 SAVERM_RS27010 xylA agmatine dehydrogenase: 2-iminopropanoate phosphoribosyltransferase: SAVERM_RS09805 SAVERM_RS07005 SAVERM_RS35085 dUTP phosphate glycine C- synthase [1-(2-amino-7-methyl-4-oxo- α D-glucono- 5-dehydro- RS16335 SAVERM_RS26180 SAVERM_RS35150 (6R)-L-erythro-6,7- a 2-O-(6-O-acyl- -D-mannosyl)- 2,3,4,5,6- protoporphyrin IX 25-hydroxycholesta- an aldehyde an alcohol pyruvate keto-D-fructose synthase: acetyltransferase: agmatinase: aspartate ammonia- BioB: bioB 7,8-dihydro-3H-pteridin- homogentisate pentachlorocyclohexanol 1,4-dien-3-one 1,5-lactone D-gluconate glutamate dihydrobiopterin 1-phosphatidyl-1D-myo-inositol hisH hisF SAVERM_RS08625 speB lyase: aspA 6-yl)]ethyl diphosphate pyruvate dehydrogenase: α-D-glucopyranose D-glucopyranose [+ 7 isozymes] L-asparagine biotin 5'-deoxyadenosine an unsulfurated AICAR gly putrescine fumarate SAVERM_RS08670 pyruvate met glu degradation I 2-oxoglutarate [sulfur carrier] RS27800 asn L-glutamate degradation 10 β L-glutamine IX (via 4-aminobutanoate) 3-methyl-2- 5,10-methylene- trans,octacis-decaprenylphospho- 4a-hydroxy-N - an [amino-group carrier protein]-C- a single 3-phenyl-2- adenosyl-cob(III) a (1->6)- - CTP asparaginase: L-glutamate seleno-L- β 3-methylcatechol an α-limit dextrin reduced riboflavin dihydroxyacetone a 3-oxosteroid L-idonate β-D-allopyranose degradation II oxobutanoate tetrahydromethanopterin -D-arabinofuranose formyltetrahydrofolate terminal-γ-(L-ornithyl)-L-glutamate stranded DNA oxopropanoate yrinate a,c-diamide D-galactan SAVERM_RS07045 degradation X homocysteine decaprenylphospho-beta- L-alanine 4a-hydroxytetrahydrobiopterin acetylornithine catechol 2,3- 4-alpha- FMN reductase: 3-oxosteroid 1- L-idonate 5- endo-beta-1,6- dCTP deaminase: D-ribose RS28355 asparaginase: glu 5-methyltetrahydropteroyltriglutamate- D-erythro-pentofuranosid- deoxyribonuclease IV: 4-hydroxyphenylpyruvate cobyric acid synthase: dihydroxyacetone degradation IV dehydratase: transaminase: dioxygenase: glucanotransferase: SAVERM_RS24600 dehydrogenase: dehydrogenase: galactanase: SAVERM_RS23060 pyranase: gln SAVERM_RS20745 glutamate decarboxylase: glu 3-methyl-2-oxobutanoate - homocysteine S- 2-ulose 2-reductase: SAVERM_RS31375 dioxygenase: hppD SAVERM_RS32990 kinase: dhaK dhaL glutamate hydroxymethyltransferase: SAVERM_RS09805 SAVERM_RS34745 SAVERM_RS08560 malQ [+ 3 isozymes] SAVERM_RS08450 SAVERM_RS34045 SAVERM_RS26860 rbsD asp SAVERM_RS18600 glutamate methyltransferase: metE SAVERM_RS17665 an [amino-group carrier protein]- a α-limit dextrin a (1->6)-β- UTP synthase large ala panB an N 10 -formyl- (2-hydroxyphenyl) (2Z,4E)-2-hydroxy-6- a 3-oxo- 5-dehydro- β glutamate decarboxylase: dehydrogenase: trans,octacis-decaprenylphospho- γ a 5'-phosphooligonucleotide adenosylcobyrate riboflavin DHAP -D-allofuranose β C-terminal- -(L-glutamate 5- with short branches ∆ 1 D-gluconate D-galactan subunit: gltB alanine SeMet -D-erythro-pentofuranosid-2-ulose 7,8-dihydrofolate acetate oxohepta-2,4-dienoate -steroid glu SAVERM_RS24035 SAVERM_RS08670 semialdehyde-2-yl)-L-glutamate RS28950 dehydrogenase: ald 4-aminobutanoate 2-oxoglutarate pyruvate 2-dehydropantoate THMPT a branched- a branched- a reduced chain chain a reduced plastocyanin amino acid amino acid plastocyanin an oxidized choline choline a dipeptide a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate lipid II (meso glutamate glutamate glutamate an inorganic an inorganic an inorganic an oxidized plastocyanin an aliphatic an aromatic glycine betaine glycine betaine glycine betaine glycine betaine glycine betaine D-fructose D-glucose 6- a nicotinamide an a sugar 6- diaminopimelate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate plastocyanin benzoate (S)-lactate a dipeptide predicted predicted anion anion anion sulfonate carboxylate pro pro pro pro pro 1-phosphate phosphate mononucleotide oligopeptide phosphate containing) ABC ABC predicted predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC transporter transporter cytochrome ABC MreD RS27455 RS26670 RS26200 SecY RS15805 RS15640 RS24055 RS23130 RS14930 RS21700 RS14635 RS11820 MscL RS11215 RS38215 RS18225 RS17945 RS17750 RS35080 FtsW RS34860 RS17365 RS30640 RS09285 RS11785 RS09505 RS13430 RS14670 RS35015 RS07105 RS05635 transporter of transporter of transporter of transporter of transporter of RS11010 RS07445 RS11255 RS15685 RS07740 RS12345 RS25695 RS32685 RS32755 RS26480 RS27120 RS27780 RS09115 of a of a RS10340 RS27760 RS12955 RS23760 RS24365 RS11595 CtaD RS11205 RS08555 ProP RS34495 RS38030 RS26560 ProP RS22895 RS06905 RS35825 RS26025 RS35470 RS28945 RS19030 RS01660 RS30485 RS30510 RS30545 RS34620 RS34785 RS05335 RS17420 RS13485 SecD RS10440 RS18115 RS38075 RS38460 RS18685 RS14410 RS07165 RS07450 RS21965 RS23105 RS23575 RS12240 RS25050 RS12485 RS32580 RS26335 RS16245 RS27650 RS28915 RS16430 c oxidase transporter a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate branched- branched- of a dipeptide chain chain choline choline a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate amino acid amino acid an inorganic an inorganic an inorganic an aliphatic an aromatic glycine betaine glycine betaine glycine betaine D-fructose D-glucose a nicotinamide an a sugar lipid II (meso glutamate glutamate glutamate glycine betaine glycine betaine benzoate (S)-lactate a dipeptide a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate anion anion anion O sulfonate carboxylate pro pro pro mononucleotide oligopeptide diaminopimelate 2 O pro pro a dipeptide containing) H O 2 a branched- a branched- 2 H O 2 chain chain amino acid amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.