Anti-CD5L (C-Terminal) Polyclonal Antibody (CPBT- 65327RC) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-CD5L (C-terminal) polyclonal antibody (CPBT- 65327RC) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview This product detects an epitope within the C-terminal (CT) region of human CD5L, also known as Apoptosis Inhibitor expressed by Macrophages (AIM), and SP alpha. CD5L is a soluble 38kD glycoprotein which is specifically produced by mature macrophages, and has been shown to support their survival and enhance phagocytic function. CD5L expression is upregulated in response to LXR/RXR heterodimer activation. CD5L has been shown to mediate the survival of macrophages in atherosclerotic plaques. Western Blotting detects a band of approximately 38kDa in Raji cell lysates.

Specificity CD5L

Immunogen 13 amino acid peptide sequence near the carboxy terminus of human CD5L.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human, Mouse

Conjugate Unconjugated

Applications IHC-P; WB

Format Purified IgG - liquid

Size 100 μg

Preservative 0.02% Sodium Azide

Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Warnings For research purposes only

GENE INFORMATION

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Official Symbol CD5L

Synonyms CD5L; CD5 molecule-like; AIM; API6; PRO229; Spalpha; SP-ALPHA; CD5 antigen-like; CT-2; apoptosis inhibitor 6; igM-associated peptide; CD5 antigen-like (scavenger receptor cysteine rich family); CD5L;

Entrez Gene ID 922

Protein Refseq NP_005885

UniProt ID O43866

Chromosome Location 1q21-q23

Function scavenger receptor activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]