Forensic Library 1720110-01
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Forensic Library Forensic LC/MS/MS Library Version 1.0 for Cliquid® Software The following description outlines the 1250 forensic compounds available in the MRM Catalogue and Library. This library and MRM catalogue, created under stringent quality control conditions using certified reference materials, can be used stand-alone to create custom screening and/or quantification methods or in conjunction with the iMethod™ Test for Drugs of Abuse Screening. The iMethod™ Test provides a pre-configured method for the screening of 700 drugs of abuse in a single run, via an MRM triggered EPI workflow on a QTRAP® series instrument. This library is verified for use on AB SCIEX 3200 The MRM catalogue can be used to build methods without the QTRAP®, 4000 QTRAP® and AB SCIEX QTRAP® 5500 need to re-infuse standards to determine and optimize MRM LC/MS/MS systems. transitions. Screening methods can be created using either the The MRM Catalog and Spectral Library both contain information MRM triggered EPI workflow on a QTRAP® type instrument, or on over 1250 drugs of abuse, metabolites, and other compounds for traditional quantification/confirmation, using two or more of forensic interest. The MRM Catalog contains up to six MRM transitions per compounds and determining the ratio between the transitions and the Library contains up to 8 full scan EPI spectra two transitions. This traditional MRM ratio approach can be used for each compound. Each compound in the library has individual on either a triple quadrupole or QTRAP® instrument. Users spectra acquired using three distinct collision energies (20 eV, select the analytes from the MRM catalog, the number of 35 eV, or 50 eV), as well as a single spectrum that is a sum of transitions per compound to use, and whether an MRM-EPI or the three energies. If it is possible to ionize the compound in both MRM ratio method should be built. Cliquid® Software polarities, spectra for both are also included, bringing the automatically creates the acquisition and processing methods. potential total number of spectra present per compound to eight. The following is a list of the 1250 compounds currently present in the library. Please note that this library is continually being expanded to include additional compounds.