medicina Article Comparing Ictal Cardiac Autonomic Changes in Patients with Frontal Lobe Epilepsy and Temporal Lobe Epilepsy by Ultra-Short-Term Heart Rate Variability Analysis Sung-Min You 1 , Hyun-Jin Jo 2 , Baek-Hwan Cho 3,4 , Joo-Yeon Song 2 , Dong-Yeop Kim 2, Yoon-Ha Hwang 2, Young-Min Shon 2, Dae-Won Seo 2,* and In-Young Kim 1,* 1 Department of Biomedical Engineering, Hanyang University, 222, Wangsimni-ro, Seongdong-gu, Seoul 04763, Korea;
[email protected] 2 Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81, Irwon-ro, Gangnam-gu, Seoul 06351, Korea;
[email protected] (H.-J.J.);
[email protected] (J.-Y.S.);
[email protected] (D.-Y.K.);
[email protected] (Y.-H.H.);
[email protected] (Y.-M.S.) 3 Medical AI Research Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81, Irwon-ro, Gangnam-gu, Seoul 06351, Korea;
[email protected] 4 Department of Medical Device Management and Research, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University School of Medicine, 81, Irwon-ro, Gangnam-gu, Seoul 06351, Korea * Correspondence:
[email protected] (D.-W.S.);
[email protected] (I.-Y.K.); Tel.: +82-2-6007-5448 (D.-W.S.); +82-2-2291-1713 (I.-Y.K.) Citation: You, S.-M.; Jo, H.-J.; Cho, Abstract: Background and Objectives: Abnormal epileptic discharges in the brain can affect the central B.-H.; Song, J.-Y.; Kim, D.-Y.; Hwang, brain regions that regulate autonomic activity and produce cardiac symptoms, either at onset or Y.-H.; Shon, Y.-M.; Seo, D.-W.; Kim, during propagation of a seizure.