CDC14A Antibody Cat. No.: 59-028

CDC14A Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

This CDC14A antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 473-500 amino acids from the C-terminal region of human CDC14A.

TESTED APPLICATIONS: WB

APPLICATIONS: For WB starting dilution is: 1:1000

PREDICTED MOLECULAR 67 kDa WEIGHT:

Properties

This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

September 27, 2021 1 https://www.prosci-inc.com/cdc14a-antibody-59-028.html PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: CDC14A

Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A, ALTERNATE NAMES: CDC14A

ACCESSION NO.: Q9UNH5

PROTEIN GI NO.: 55976620

GENE ID: 8556

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, BACKGROUND: suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq].

REFERENCES: 1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

2) Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :

3) Mocciaro, A., et al. J. Cell Biol. 189(4):631-639(2010)

4) Song, S.Y., et al. APMIS 118(5):389-393(2010)

ANTIBODIES FOR RESEARCH USE ONLY.

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September 27, 2021 2 https://www.prosci-inc.com/cdc14a-antibody-59-028.html