Wednesday May 29 SEVENTH SESSION: QUALITY OF LIFE How to participate to Poster Session ANALYSIS Interested participants may visit the following link and Chairmen: Kassim Javaid and Pablo Florenzano read through the instructions for submission. 12.30 Bond a Platform for Rare Bone Disorders https://fibrousdysplasia.org/research/international-fd- mas-consortium-poster-abstract-submissions/ Luca Sangiorgi, Bologna, I 12.50 Driving Improvement in Clinical Centres – For more information and registration please contact: Effectiveness, Efficiency and Patient [email protected] Experience – Designing a Global Audit of Clinical Services Based on the Global Scientific Administration Pathway FIRMO Foundation Valter Dal Pos, Torino, I Via Reginaldo Giuliani, 195/a 13.10 Bringing Together Research Across 50141 | Borders: Natural History of Disease [email protected] Database Opportunities in the ERN Tel. +39 055 2336663 and Further Afield Michael Collins, NIH NIDCR Bethesda, USA Organisation Administration 13.30 Lunch and Poster Session EXPOS srl 13.30 End session ECM Via Ragazzi del 99, 51 14.00 International Patient Afternoon organized 50141 Florence | Italy 19.00 by Eamas Tel. +39 055 2336663

General Information Ecm Provider Nico Srl | Via Aurora 39 | 00187 | Italy ECM accredited event Number of credits provided: 11 With the support of: Accredited professions: Disciplines: Pathological Anatomy - Maxillofacial Surgery - Endocrinology - Physiology - Genetics - Internist, Neuro- surgery - Oncology - Orthopedics - Pediatrics - Radiology. Registration The conference is limited to 60 attendes. Those interested in participating please send an email with: Surname / name / address / email Send to: [email protected] Poster Session Scientific contributions will be accepted in the form of Po- Florence, May 28-29, 2019 sters that will be posted next to the presenter at the Con- ference. The author of the Poster must present next to the “This project has received funding from panel on the and on the the European Union’s Horizon 2020 Albani Hotel 28th May at 12.40pm 29th May research and innovation programme at 13.30pm. under grant agreement No 847078” Via Fiume, 12 - Florence 12.20. MAS – Associated Gastrointestinal Tuesday May 28 Pathologies Wednesday May 29 Michael Collins, NIH NIDCR Bethesda, USA 8.00 Registration 12.40 Lunch and Poster Session FIFTH SESSION: THE PAIN ISSUE 8.30 Opening and Welcome Chairmen: Maria Luisa Brandi THIRD SESSION: INSIGHT IN DIAGNOSIS and Anne Marie Heegaard FIRST SESSION: BASIC RESEARCH Chairmen: Natasha M Appelman-Dijkstra 8.30 Pathogenetic Mechanisms of Bone Pain Chairmen: Michael Collins and Luca Sangiorgi 14.00 Fibrous Dysplasia Imitating Malignancy Diego Fornasari, University of , I Rodolfo Capanna, University of Pisa, I 8.45 GNAS Spectrum of Disorders 8.50 Clinical Evaluation of Bone Pain Giovanna Mantovani, University of Milan, I 14.20 Use of Biological Markers in FD/MAS Renato Vellucci, AOU Careggi, Florence, I Pablo Florenzano, Catholic University 9.05 The Role of Stem Cells in FD Initiation of Santiago, Chile 9.10 What Are We Doing to Answer Patients’ and Maintenance Needs? Mara Riminucci, University of Rome 14.40 Imaging modalities in FD/MAS Roland Chapurlat, University of Lyon, F “La Sapienza”, I Alison Boyce, NIH NIDCR Bethesda, USA 9.30 Designing Analgesic Trials 9.25 Mouse Models of FD/MAS 15.00 Coffee Break Panel Discussion Yingzi Yang, Harvard Dental School, Boston, 10.10 Coffee Break MA, USA FOURTH SESSION: SURGICAL THERAPY Chairmen: Giovanni Beltrami and Lorenzo Genitori 9.45 Human Cellular Models of FD/MAS SIXTH SESSION: PHARMACOLOGICAL Ed Hsiao, UCSF, San Francisco, USA 15.15 Craniofacial Fibrous Dysplasia: THERAPY 10.05 Gene Mutation Analysis in FD/MAS The Point of View of the Neurosurgeon Chairmen: Alison Boyce and Aris Economides Luisa De Sanctis, University of , I Lorenzo Genitori, AOU Meyer, Florence, I 10.30 FD/MAS: Treating Children and 10.25 Future Agenda of Basic Research 15.35 Craniofacial Fibrous Dysplasia: Adolescents with Antiresorptive Panel Discussion The Point of View of the Maxillofacial Surgeon medications 10.45 Coffee Break Giuseppe Spinelli, AOU of Careggi, Florence Alison Boyce, NIH, Bethesda, USA 15.55 Scoliosis in FD/MAS 10.50 Results from Recent Clinical Trials SECOND SESSION: EXTRASKELETAL DISEASE Robert Stanton, Nemours Ch, Orlando, USA Roland Chapurlat, University of Lyon, F Chairmen: Neeven Hamdy and Daniele Tessaris 16.15 The Expert Orthopaedic Surgeon 11.10 Osteoporosis Treatment in Special Patient Populations 11.00 Endocrine Diseases in MAS Giovanni Beltrami, AOU of Careggi, Florence Laura Masi, AOU of Careggi, Florence, I Daniele Tessaris, University of Turin, I 16.35 Surgical Treatment of Bone Lesions 11.30 Denosumab Trials 11.20 Gonadal Diseases in MAS in Mc Cune- Albright Syndrome. Neveen Hamdy, Leiden University, NL Malgorzata Wasniewska, University A Twenty Years Experience. of Messina, I Ernesto Ippolito, University of Rome “Tor Vergata” 11.50 Prospects for the Future Panel Discussion 11.40 The Role of Inflammation in FD/MAS 16.55 Presentation from the Winner of the Roland Chapurlat, University of Lyon, F Charles Harles Award for Excellence in FD/MAS Research 12.00 Cancer Risk in FD/MAS Natasha M Appelman-Dijkstra, Leiden 17.10 FD/MAS International Consortium Terms University, NL of Reference