Notice of Opposition
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Guidance for Identification and Naming of Substance Under REACH
Guidance for identification and naming of substances under 3 REACH and CLP Version 2.1 - May 2017 GUIDANCE Guidance for identification and naming of substances under REACH and CLP May 2017 Version 2.1 2 Guidance for identification and naming of substances under REACH and CLP Version 2.1 - May 2017 LEGAL NOTICE This document aims to assist users in complying with their obligations under the REACH and CLP regulations. However, users are reminded that the text of the REACH and CLP Regulations is the only authentic legal reference and that the information in this document does not constitute legal advice. Usage of the information remains under the sole responsibility of the user. The European Chemicals Agency does not accept any liability with regard to the use that may be made of the information contained in this document. Guidance for identification and naming of substances under REACH and CLP Reference: ECHA-16-B-37.1-EN Cat. Number: ED-07-18-147-EN-N ISBN: 978-92-9495-711-5 DOI: 10.2823/538683 Publ.date: May 2017 Language: EN © European Chemicals Agency, 2017 If you have any comments in relation to this document please send them (indicating the document reference, issue date, chapter and/or page of the document to which your comment refers) using the Guidance feedback form. The feedback form can be accessed via the EVHA Guidance website or directly via the following link: https://comments.echa.europa.eu/comments_cms/FeedbackGuidance.aspx European Chemicals Agency Mailing address: P.O. Box 400, FI-00121 Helsinki, Finland Visiting address: Annankatu 18, Helsinki, Finland Guidance for identification and naming of substances under 3 REACH and CLP Version 2.1 - May 2017 PREFACE This document describes how to name and identify a substance under REACH and CLP. -
Issues in CPPD Nomenclature and Classification
Current Rheumatology Reports (2019) 21: 49 https://doi.org/10.1007/s11926-019-0847-4 CRYSTAL ARTHRITIS (L STAMP, SECTION EDITOR) Issues in CPPD Nomenclature and Classification Sara K. Tedeschi1 Published online: 25 July 2019 # Springer Science+Business Media, LLC, part of Springer Nature 2019 Abstract Purpose of Review This paper covers confusion and challenges in the nomenclature of calcium pyrophosphate deposition disease. Clinicians, investigators, and patients are faced with a variety of terms that are used to describe CPPD and its phenotypes, and clarity is greatly needed to help advance research and patient care. Motivation for the upcoming development of CPPD classification criteria is reviewed. Recent Findings EULAR proposed recommended terminology for CPPD in 2011. International Classification of Diseases (ICD- 9 and ICD-10) billing codes identify definite or probable CPPD with variable accuracy depending on the clinical setting and comparator group. READ diagnostic codes have been employed to identify pseudogout in UK datasets but their accuracy has not been evaluated. CPPD classification criteria will provide a system for identifying a relatively homogenous group of patients to be included in clinical studies, enabling comparison of outcomes across studies. Summary CPPD nomenclature remains challenging for clinicians, investigators, and patients. A lay-friendly definition of CPPD, using easily accessible terminology, would be welcome. CPPD classification criteria are a necessary step in moving forward CPPD clinical research and may involve a range of clinical, laboratory, and imaging modalities. Keywords CPPD . Pseudogout . Acute CPP crystal arthritis . Classification criteria . Terminology . Nomenclature Introduction experts have noted that confusing nomenclature and a lack of classification criteria hinder our understanding of this com- Calcium pyrophosphate deposition (CPPD) disease represents mon arthritis [1, 4, 5]. -
Guidance Document to Mitigate the Potential for Benzene Formation in Beverages
Guidance Document to Mitigate the Potential for Benzene Formation in Beverages Prepared in cooperation with the International Council of Beverages Associations For further information about this Guidance, please contact: Canadian Beverage Association 20 Bay St, WaterPark Place 11th Floor, Toronto ON M5J 2N8 Tel: (416) 362-2424 www.canadianbeverage.ca Guidance Document to Mitigate the Potential for Benzene Formation in Beverages TABLE OF CONTENTS 1. Introduction ........................................................................................................................ 1 2. Background ........................................................................................................................ 1 3. Trigger and Mitigating Factors for Benzene Formation in Beverages.................................. 2 4. Key recommendations to beverage producers to minimize benzene formation .................. 3 5. Guidance: Testing for the presence of benzene in beverages ........................................... 3 6. Guidance: Formulation Control Strategies ......................................................................... 4 Guidance Document to Mitigate the June 2006 Potential for Benzene Formation in Beverages 1 of 5 1. Introduction The Canadian Beverage Association is the national trade organization representing the broad spectrum of companies that manufacture and distribute non-alcoholic beverages in Canada. The members of the Canadian Beverage Association produce, distribute, and sell a variety of non-alcoholic beverages, -
Draft Screening Assessment Benzoates Chemical Abstracts
Draft Screening Assessment Benzoates Chemical Abstracts Service Registry Numbers 93-58-3 93-89-0 120-50-3 120-55-8 136-60-7 614-33-5 8024-05-3 27138-31-4 68052-23-3 Environment and Climate Change Canada Health Canada December 2017 Synopsis Pursuant to sections 68 and 74 of the Canadian Environmental Protection Act, 1999 (CEPA), the Minister of the Environment and the Minister of Health have conducted a screening assessment of 9 of 10 substances referred to collectively under the Chemicals Management Plan as the Benzoates group. These 9 substances were identified as priorities for assessment as they met categorization criteria under subsection 73(1) of CEPA or were considered a priority on the basis of other human health concerns. One of the 10 substances was subsequently determined to be of low concern for risk to ecological or human health and the decision for this substance is provided in a separate report.1 Accordingly, this screening assessment addresses the 9 substances listed in the table below. Substances in the Benzoates group CAS RN2 Domestic Substances List name Common name 93-58-3 Benzoic acid, methyl ester Methyl benzoate 93-89-0a Benzoic acid, ethyl ester Ethyl benzoate 120-50-3a Benzoic acid, 2-methylpropyl ester Isobutyl benzoate Diethylene glycol 120-55-8 Ethanol, 2,2’-oxybis-, dibenzoate dibenzoate 136-60-7 Benzoic acid, butyl ester Butyl benzoate 614-33-5 1,2,3-Propanetriol, tribenzoate Tribenzoin 8024-05-3b Oils, tuberose Tuberose oil Dipropylene glycol 27138-31-4 Propanol, oxybis-, dibenzoate dibenzoate 1,3-Pentanediol, 2,2,4-trimethyl-, Trimethylpentanediyl 68052-23-3 dibenzoate dibenzoate a This substance was not identified under subsection 73(1) of CEPA but was included in this assessment as it was considered a priority on the basis of other human health concerns. -
Physical Properties of Acidic Calcium Phosphate Cements
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1195 Physical Properties of Acidic Calcium Phosphate Cements JOHANNA UNOSSON ACTA UNIVERSITATIS UPSALIENSIS ISSN 1651-6214 ISBN 978-91-554-9081-2 UPPSALA urn:nbn:se:uu:diva-233637 2014 Dissertation presented at Uppsala University to be publicly examined in Polhemsalen, Ångströmlaboratoriet, Uppsala, Friday, 5 December 2014 at 09:15 for the degree of Doctor of Philosophy. The examination will be conducted in English. Faculty examiner: Professor Uwe Gbureck (University of Wuerzburg, Germany). Abstract Unosson, J. 2014. Physical Properties of Acidic Calcium Phosphate Cements. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1195. 73 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9081-2. The gold standard for bone replacement today, autologous bone, suffers from several disadvantages, such as the increased risk of infection due to the need for two surgeries. Degradable synthetic materials with properties similar to bone, such as calcium phosphate cements, are a promising alternative. Calcium phosphate cements are suited for a limited amount of applications and improving their physical properties could extend their use into areas previously not considered possible. For example, cement with increased strength could be used as load bearing support in selected applications. The focus of this thesis is, therefore, on how the physical properties of acidic calcium phosphate cements (brushite cements) are affected by compositional variations, with the ultimate aim of making it possible to formulate brushite cements with desired properties. In this thesis a method to measure the porosity of a cement was developed. -
Orthophosphoric Acid and Inorganic Phosphate Compounds, Including Ortho- and Condensed Phosphates) (Various Casrns Included in the Text)
EPA/690/R-11/040F l Final 3-01-2011 Provisional Peer-Reviewed Toxicity Values for Inorganic Phosphates (Orthophosphoric Acid and Inorganic Phosphate Compounds, Including Ortho- and Condensed Phosphates) (Various CASRNs included in the text) Superfund Health Risk Technical Support Center National Center for Environmental Assessment Office of Research and Development U.S. Environmental Protection Agency Cincinnati, OH 45268 AUTHORS, CONTRIBUTORS, AND REVIEWERS CHEMICAL MANAGER Custodio V. Muianga, PhD, MPH National Center for Environmental Assessment, Cincinnati, OH DRAFT DOCUMENT PREPARED BY ICF International 9300 Lee Highway Fairfax, VA 22031 PRIMARY INTERNAL REVIEWERS Dan D. Petersen, PhD, DABT National Center for Environmental Assessment, Cincinnati, OH Anuradha Mudipalli, MSc, PhD National Center for Environmental Assessment, Research Triangle Park, NC This document was externally peer reviewed under contract to Eastern Research Group, Inc. 110 Hartwell Avenue Lexington, MA 02421-3136 Questions regarding the contents of this document may be directed to the U.S. EPA Office of Research and Development’s National Center for Environmental Assessment, Superfund Health Risk Technical Support Center (513-569-7300). TABLE OF CONTENTS COMMONLY USED ABBREVIATIONS .................................................................................... ii BACKGROUND .............................................................................................................................3 HISTORY ...................................................................................................................................3 -
Chemical Names and CAS Numbers Final
Chemical Abstract Chemical Formula Chemical Name Service (CAS) Number C3H8O 1‐propanol C4H7BrO2 2‐bromobutyric acid 80‐58‐0 GeH3COOH 2‐germaacetic acid C4H10 2‐methylpropane 75‐28‐5 C3H8O 2‐propanol 67‐63‐0 C6H10O3 4‐acetylbutyric acid 448671 C4H7BrO2 4‐bromobutyric acid 2623‐87‐2 CH3CHO acetaldehyde CH3CONH2 acetamide C8H9NO2 acetaminophen 103‐90‐2 − C2H3O2 acetate ion − CH3COO acetate ion C2H4O2 acetic acid 64‐19‐7 CH3COOH acetic acid (CH3)2CO acetone CH3COCl acetyl chloride C2H2 acetylene 74‐86‐2 HCCH acetylene C9H8O4 acetylsalicylic acid 50‐78‐2 H2C(CH)CN acrylonitrile C3H7NO2 Ala C3H7NO2 alanine 56‐41‐7 NaAlSi3O3 albite AlSb aluminium antimonide 25152‐52‐7 AlAs aluminium arsenide 22831‐42‐1 AlBO2 aluminium borate 61279‐70‐7 AlBO aluminium boron oxide 12041‐48‐4 AlBr3 aluminium bromide 7727‐15‐3 AlBr3•6H2O aluminium bromide hexahydrate 2149397 AlCl4Cs aluminium caesium tetrachloride 17992‐03‐9 AlCl3 aluminium chloride (anhydrous) 7446‐70‐0 AlCl3•6H2O aluminium chloride hexahydrate 7784‐13‐6 AlClO aluminium chloride oxide 13596‐11‐7 AlB2 aluminium diboride 12041‐50‐8 AlF2 aluminium difluoride 13569‐23‐8 AlF2O aluminium difluoride oxide 38344‐66‐0 AlB12 aluminium dodecaboride 12041‐54‐2 Al2F6 aluminium fluoride 17949‐86‐9 AlF3 aluminium fluoride 7784‐18‐1 Al(CHO2)3 aluminium formate 7360‐53‐4 1 of 75 Chemical Abstract Chemical Formula Chemical Name Service (CAS) Number Al(OH)3 aluminium hydroxide 21645‐51‐2 Al2I6 aluminium iodide 18898‐35‐6 AlI3 aluminium iodide 7784‐23‐8 AlBr aluminium monobromide 22359‐97‐3 AlCl aluminium monochloride -
Chemical Specific Parameters May 2021
Regional Screening Level (RSL) Chemical-specific Parameters Supporting Table May 2021 Contaminant Molecular Weight Volatility Parameters Melting Point Density Diffusivity in Air and Water Partition Coefficients Water Solubility Tapwater Dermal Parameters H` HLC H` and HLC VP VP MP MP Density Density Dia Diw Dia and Diw Kd Kd Koc Koc log Kow log Kow S S B τevent t* Kp Kp Analyte CAS No. MW MW Ref (unitless) (atm-m3/mole) Ref (mmHg) Ref (C) Ref (g/cm3) Ref (cm2/s) (cm2/s) Ref (L/kg) Ref (L/kg) Ref (unitless) Ref (mg/L) Ref (unitless) (hr/event) (hr) (cm/hr) Ref Acephate 30560-19-1 1.8E+02 PHYSPROP 2.0E-11 5.0E-13 EPI 1.7E-06 PHYSPROP 8.8E+01 PHYSPROP 1.4E+00 CRC 3.7E-02 8.0E-06 WATER9 (U.S. EPA, 2001) 1.0E+01 EPI -8.5E-01 PHYSPROP 8.2E+05 PHYSPROP 2.1E-04 1.1E+00 2.7E+00 4.0E-05 EPI Acetaldehyde 75-07-0 4.4E+01 PHYSPROP 2.7E-03 6.7E-05 PHYSPROP 9.0E+02 PHYSPROP -1.2E+02 PHYSPROP 7.8E-01 CRC 1.3E-01 1.4E-05 WATER9 (U.S. EPA, 2001) 1.0E+00 EPI -3.4E-01 PHYSPROP 1.0E+06 PHYSPROP 1.3E-03 1.9E-01 4.5E-01 5.3E-04 EPI Acetochlor 34256-82-1 2.7E+02 PHYSPROP 9.1E-07 2.2E-08 PHYSPROP 2.8E-05 PHYSPROP 0.0E+00 EPI 1.1E+00 PubChem 2.2E-02 5.6E-06 WATER9 (U.S. -
Inhibition of a Gold-Based Catalyst in Benzyl Alcohol Oxidation: Understanding and Remediation
Catalysts 2014, 4, 89-115; doi:10.3390/catal4020089 OPEN ACCESS catalysts ISSN 2073-4344 www.mdpi.com/journal/catalysts Article Inhibition of a Gold-Based Catalyst in Benzyl Alcohol Oxidation: Understanding and Remediation Emmanuel Skupien 1,*, Rob J. Berger 2, Vera P. Santos 1, Jorge Gascon 1, Michiel Makkee 1, Michiel T. Kreutzer 3, Patricia J. Kooyman 1,*, Jacob A. Moulijn 1 and Freek Kapteijn 1 1 Catalysis Engineering, Chemical Engineering Department, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands; E-Mails: [email protected] (V.P.S.); [email protected] (J.G.); [email protected] (M.M.); [email protected] (J.A.M.); [email protected] (F.K.) 2 Anaproc c/o Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands; E-Mail: [email protected] 3 Product & Process Engineering, Chemical Engineering Department, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands; E-Mail: [email protected] * Authors to whom correspondence should be addressed; E-Mails: [email protected] (E.S.); [email protected] (P.J.K.); Tel.: +31-152-789-077 (P.J.K.); Fax: +31-152-785-006 (P.J.K.). Received: 9 October 2013; in revised form: 26 January 2014 / Accepted: 26 March 2014 / Published: 15 April 2014 Abstract: Benzyl alcohol oxidation was carried out in toluene as solvent, in the presence of the potentially inhibiting oxidation products benzaldehyde and benzoic acid. Benzoic acid, or a product of benzoic acid, is identified to be the inhibiting species. -
Benzene Fears Prompt Call for Banning Some Soft Drinks at Schools
______________________________________________________________________________ Knight Ridder Newspapers Benzene Fears Prompt Call for Banning Some Soft Drinks at Schools March 27, 2006 David Goldstein <<<>>> Retrieved 03/28/06 from http://www.bradenton.com/mld/bradenton/news/nation/14199793.htm ______________________________________________________________________________ WASHINGTON - Some leading public-health experts want education officials to ban certain soft drinks from public schools until they're proved safe and free of the cancer-causing chemical benzene. "It is irresponsible to provide to schoolchildren products that are unhealthy and may contain a carcinogen," they said in a letter sent last week to state education officials. Benzene is a common industrial chemical that the Environmental Protection Agency classifies as a human carcinogen. Long-term exposure can cause leukemia and other blood cancers, according to the Centers for Disease Control and Prevention. Benzene isn't an ingredient in soft drinks, but it can form when two commonly found ingredients react: ascorbic acid, otherwise known as vitamin C, and the preservatives sodium benzoate or potassium benzoate. The reaction can happen when products are exposed to light or heat. "Soft drinks that contain ascorbic acid and sodium or potassium benzoate include Diet Pepsi Wild Cherry, Fanta Orange, Hawaiian Punch, Mug Root Beer, Pepsi Vanilla, Sierra Mist, Sunkist and Tropicana Lemonade, among others," the letter said. The signatories, who included experts in pediatrics and activists for student health, asked that state and local education officials halt the marketing and sales of certain soft drinks in schools "until you can look parents in the eye and assure them that their children will suffer no harm." Kevin Keane, a spokesman for the American Beverage Association, the trade group that represents soft-drink manufacturers, said the letter was "irresponsible and reckless" and that the group behind the letter, Commercial Alert, has a history of "bashing" industry. -
Safety Data Sheet
SAFETY DATA SHEET Preparation Date: 10/13/2017 Revision Date: 10/13/2017 Revision Number: G1 1. IDENTIFICATION Product identifier Product code: P1173 Product Name: POTASSIUM BENZOATE, CRYSTAL, REAGENT Other means of identification Synonyms: Benzoic acid, potassium salt CAS #: 582-25-2 RTECS # DH6483850 CI#: Not available Recommended use of the chemical and restrictions on use Recommended use: Preservative. Uses advised against No information available Supplier: Spectrum Chemical Mfg. Corp 14422 South San Pedro St. Gardena, CA 90248 (310) 516-8000 Order Online At: https://www.spectrumchemical.com Emergency telephone number Chemtrec 1-800-424-9300 Contact Person: Martin LaBenz (West Coast) Contact Person: Ibad Tirmiz (East Coast) 2. HAZARDS IDENTIFICATION Classification This chemical is not considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Not a dangerous substance or mixture according to the Globally Harmonized System (GHS) Label elements Not classified Hazards not otherwise classified (HNOC) Not Applicable Other hazards Not available Product code: P1173 Product name: POTASSIUM 1 / 10 BENZOATE, CRYSTAL, REAGENT 3. COMPOSITION/INFORMATION ON INGREDIENTS Components CAS-No. Weight % Potassium Benzoate 582-25-2 100 4. FIRST AID MEASURES First aid measures General Advice: National Capital Poison Center in the United States can provide assistance if you have a poison emergency and need to talk to a poison specialist. Call 1-800-222-1222. Skin Contact: Wash off immediately with soap and plenty of water removing all contaminated clothing and shoes. Get medical attention if irritation develops. Consult a physician if necessary. Eye Contact: Flush eyes with water for 15 minutes. Get medical attention if irritation occurs. -
A Review on Calcium Pyrophosphate and Other Related Phosphate Nano Bio-Materials and Their Applications
4R4ev. Adv. Mater. Sci. 48 (2017) 44-57 S. R. Vasant and M. J. Joshi A REVIEW ON CALCIUM PYROPHOSPHATE AND OTHER RELATED PHOSPHATE NANO BIO-MATERIALS AND THEIR APPLICATIONS Sonal R. Vasant1 and M. J. Joshi2 1Government Engineering College, Rajkot, Gujarat, India 2Department of Physics, Saurashtra University, Rajkot, Gujarat, India Received: July 29, 2016 Abstract. Over the past few decades, a little word with big potential has been rapidly insinuating into the world’s consciousness, nano. The nano-scale structures permit the control of funda- mental properties of the materials without changing their chemical structure. Living organisms can create amazing ways to produce high performance materials that involve not only creation of implants, replacing bone tissues and organs, but also synthesis of biologically active materials promoting the fullest restoration of tissues and maintenance of necessary functions of an organ- ism. In the biomaterial research field, nowadays, a great attention is given to bone substitute materials, particularly, calcium phosphate based bio-materials play important roles in clinical applications as it possesses high bio-compatibility and excellent ability to undergo varying de- grees of resorbability. These materials show a positive interaction with living tissue that includes differentiation of immature cells towards bone cells and also have chemical bonding to the bone along the interface, thought to be triggered by the adsorption of bone growth-mediating proteins at the bio-materials surface. In the present review paper an attempt is made to cover properties and applications of various phosphate nano bio-materials like calcium phosphate, calcium polyphosphate, calcium pyrophosphate etc over a time span right from 1920 to 2016.