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The Informant Issue10v2
The Friedman Brain Institute is proud to present the 10th issue of the FBI Informant. The Informant is a triennial newsletter highlighting announcements and events for basic and clinical neuroscience at Mount Sinai. The purpose of riedman rain nstitute the Informant is to keep everyone abreast of all that is going on in and out of the F B I labs and clinics that comprise the Friedman Brain Institute, as well as acknowledge those individuals responsible for its success. In addition to sharing the information, our hope is that the Informant can be used as a tool to inspire, informant congratulate, and support one another. Announcements 5th Annual Neuroscience Retreat While exciting science and the exchange of information form the centerpiece of the Friedman Brain Institute’s Annual Neuroscience Retreat, it is the participation and social interactions of the various departments that make these retreats so effective and enjoyable. This year’s retreat took place on Friday, April 26th, 2013 at the New York Academy of Medicine. The morning session included a April 26, 2013 New York Academy of Medicine 1216 Fifth Avenue Dr. Daniela Schiller Geoffrey W. Smith Lauren Friedman stirring talk from Eric Nestler, director of the Friedman Brain Keynote Speaker Guest Speaker Guest Speaker Assistant!Professor of Director, President, Psychiatry and Center for Technology, Sinai Neuroscience Neuroscience Innovation and Outreach Program “SNOP” Institute and chair of Neuroscience Department. Dr. Nestler Entrepreneurship highlighted the successes of the Friedman Brain Institute and the 5th Annual Neuroscience Retreat presented ideas for the path forward. Friedman Brain Institute and the Neuroscience Training Area Keynote speaker Daniela Schiller gave a thought-provoking lecture about her group’s work aimed at understanding how the brain handles social interaction tasks. -
Schizophrenia: Could It Be Prevented?
SCHIZOPHRENIA : COULD IT BE PREVENTED ? A SATELLITE MEETING OF THE 2014 ANNUAL MEETING OF THE SOCIETY OF BIOLOGICAL PSYCHIATRY MAY 7, 2014 NEW YORK HILTON MIDTOWN TABLE OF CONTENTS WELCOME MESSAGE 3 ACKNOWLEDGMENTS 4 PROGRAM 5 INTRODUCTION – PROF . MICHEL CUENOD 6 SESSION 1: CHAIRS & SPEAKERS 7 SESSION 2: CHAIRS & SPEAKERS 14 SESSION 3: CHAIRS & SPEAKERS 19 2 WELCOME MESSAGE Early detection of psychotic disorders has recently become a focus for research and clinical development, leading to a major conceptual shift in psychiatry, and to the development of a preventive approach to psychiatric disorders. Based on emerging evidence that treatment delay has a negative impact on outcome, specialized programs to reduce the duration of untreated psychosis and develop specifically adapted treatments have been initiated worldwide. To this effect, it is essential to understand the underlying causes and mechanisms in order to identify key biomarkers profiles, and to develop novel therapeutic and preventive measures based on the etio-pathophysiology. Our Symposium brings together a panel of distinguished leaders in the field, who will present the state of the art of schizophrenia research with focus on pathophysiological mechanisms, genetic and environmental risk factors and their interaction during neurodevelopment. Dialogs between academia and industry on innovative solutions to therapeutic targets will contribute to shape the perspectives on preventive measures. Details regarding the course of the Symposium as well as our speakers and chairs are listed below. We trust that they will meet with your interest, and that we will have an opportunity to share experience, expand our networks, discuss collaborations and cultivate friendships. We thank you for joining us and look forward to a fruitful event. -
Acute Systemic Inflammation Up-Regulates Secretory Sphingomyelinase in Vivo: a Possible Link Between Inflammatory Cytokines and Atherogenesis
Acute systemic inflammation up-regulates secretory sphingomyelinase in vivo: A possible link between inflammatory cytokines and atherogenesis Ma-Li Wong*, Boxun Xie†, Nan Beatini†, Phan Phu‡, Sudhir Marathe†, Anthony Johns§, Philip W. Gold‡, Emmet Hirsch¶, Kevin Jon Williamsʈ, Julio Licinio*, and Ira Tabas†** *Department of Psychiatry and Biobehavioral Sciences, University of California, School of Medicine, Los Angeles, CA 90095-1761; Departments of †Medicine, Anatomy, and Cell Biology and ¶Obstetrics and Gynecology, Columbia University, New York, NY 10032; ‡Clinical Neuroendocrinology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892-1284; §Berlex Biosciences, Richmond, CA 94804; and ʈDorrance H. Hamilton Research Laboratories, Division of Endocrinology, Diabetes, and Metabolic Diseases, Thomas Jefferson University, Philadelphia, PA 19107 Edited by S. M. McCann, Pennington Biomedical Research Center, Baton Rouge, LA, and approved May 23, 2000 (received for review March 7, 2000) Inflammation plays a critical role in atherogenesis, yet the medi- sphingomyelinase (SMase) (20, 21). Ceramide generated from ators linking inflammation to specific atherogenic processes re- SMase activation has been reported to play roles in cytokine- main to be elucidated. One such mediator may be secretory mediated apoptosis, cellular differentiation, and cellular senes- sphingomyelinase (S-SMase), a product of the acid sphingomyeli- cence (20, 21), each of which may be important in the inflam- nase gene. The secretion of S-SMase by cultured endothelial cells matory response. Whereas studies in vitro have suggested roles is induced by inflammatory cytokines, and in vivo data have for several different mammalian SMase activities in various implicated S-SMase in subendothelial lipoprotein aggregation, ceramide signaling pathways (20, 21), a product of the acid macrophage foam cell formation, and possibly other atherogenic SMase (ASM) gene has been implicated in several specific processes. -
ENIGMA and the Individual: Predicting Factors That Affect the Brain in 35 Countries Worldwide☆,☆☆,★
NeuroImage 145 (2017) 389–408 Contents lists available at ScienceDirect NeuroImage journal homepage: www.elsevier.com/locate/ynimg ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide☆,☆☆,★ Paul M. Thompson a,s, Ole A. Andreassen b,c, Alejandro Arias-Vasquez d, Carrie E. Bearden e,f,g, Premika S. Boedhoe h,bk,bl, Rachel M. Brouwer i,RandyL.Bucknerj, Jan K. Buitelaar k,l,KazimaB.Bulayevam, Dara M. Cannon n,o, Ronald A. Cohen p, Patricia J. Conrod q,AndersM.Daler, Ian J. Deary t, Emily L. Dennis a, Marcel A. de Reus i, Sylvane Desrivieres u, Danai Dima v,w, Gary Donohoe x,SimonE.Fishery,k, Jean-Paul Fouche z, Clyde Francks y,k, Sophia Frangou w, Barbara Franke aa,ab,k,HabibGanjgahiac, Hugh Garavan ad, David C. Glahn ae,af,HansJ.Grabeag,ah, Tulio Guadalupe y,ai, Boris A. Gutman a, Ryota Hashimoto aj,DerrekP.Hibara, Dominic Holland r, Martine Hoogman aa,k, Hilleke E. Hulshoff Pol i, Norbert Hosten ak, Neda Jahanshad a, Sinead Kelly a,PeterKochunoval, William S. Kremen am,PhilH.Leean,ao,ap, Scott Mackey aq, Nicholas G. Martin as, Bernard Mazoyer ar,ColmMcDonaldo, Sarah E. Medland as, Rajendra A. Morey at, Thomas E. Nichols au,av,TomasPausaw,ax,ay,ZdenkaPausovaaz,ba, Lianne Schmaal bk,bl, Gunter Schumann u, Li Shen bb,bc, Sanjay M. Sisodiya bd, Dirk J.A. Smit be,bl,JordanW.Smollerbf,DanJ.Steinz,bg, Jason L. Stein a,bh, Roberto Toro bi, Jessica A. Turner bj, Martijn P. van den Heuvel i, Odile L. van den Heuvel h,bk,bl, Theo G.M. -
Telomere Length and Bipolar Disorder
King’s Research Portal DOI: 10.1038/npp.2017.125 Document Version Version created as part of publication process; publisher's layout; not normally made publicly available Link to publication record in King's Research Portal Citation for published version (APA): Powell, T., Dima, D., Frangou, S., & Breen, G. D. (2017). Telomere length and bipolar disorder. Neuropsychopharmacology . https://doi.org/10.1038/npp.2017.125 Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. And where the final published version is provided on the Research Portal, if citing you are again advised to check the publisher's website for any subsequent corrections. General rights Copyright and moral rights for the publications made accessible in the Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognize and abide by the legal requirements associated with these rights. •Users may download and print one copy of any publication from the Research Portal for the purpose of private study or research. •You may not further distribute the material or use it for any profit-making activity or commercial gain •You may freely distribute the URL identifying the publication in the Research Portal Take down policy If you believe that this document breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. -
Bb-Wasp-V5.Pdf
Content 4 / Welcome Address 5 / About WASP 7 / Scientic Committee 8 / National Organizing Committee International Advisory Board 9 / Council of Past Presidents 10 / Invited Speakers WASP Early Career Psychiatrists 15 / Fellowship Program 16 / Why come to Bucharest 17 / Useful Information 19 / Types of badges 21 / General Outline of Scientific Sessions 23 / Scientific Programme 23 / Day 0, Thursday, 24th of October 25 / Day 1, Friday, 25th of October 40 / Day 2, Saturday, 26th of October 62 / Day 3, Sunday, 27th of October 75 / Day 4, Monday, 28th of October 87 / E-Poster Session Recommendations for Speakers 96 / and Chairs 99 / Exhibition Map 100 / Information about Bucharest Content 102 / Photo Contest 103 / Notes 23rd WORLD CONGRESS OF SOCIAL PSYCHIATRY / 25-28 October 2019 / Bucharest Message from the President We are delighted to invite you to the 23rd Congress of the World Association of Social Psychiatry at Bucharest, October 25-28, 2019. This is a special occasion for all of us including our member societies, social psychiatrists and mental health professionals all over the world to meet together and engage in scientific deliberations. The theme of the Congress, “Social determinants of mental health and access to care” is contemporary and relevant. It reflects our concern for mental health in this age of globalization, commercialization and the merging of boundaries between nations. Prof. Roy Abraham Kallivayalil President, World Association of Social Psychiatry Message from LOC Chair We are very pleased that this prestigious event and all its formidable speakers have chosen Romania as a destination for this year congress. Personally, I have prepared a very up to date topic materialized in a Master Class on Preventing Youth Suicide in Europe to which I invited everyone to attend. -
Pan American Division Newsletter
Royal College of Psychiatrists Pan American Division Newsletter April 2018 (Issue 40) Dear Colleagues Following the recent election, we welcome to the Division Prof. Kenneth Kaufman as Vice-hair and Prof Allan Tasman as Financial Officer. Prof. Sophia Frangou will continue in her role as chair. Prof. Kaufman is well known to all the members of the Division because of his dedicated and long-standing contribution which started with his appointment as Financial Officer and most recently as Acting Vice-Chair. Prof Tasman brings with him a wealth of experience as he has previously served as president of the American Association of Directors of Psychiatric Residency Training, of the Association for Academic Psychiatry, of the American Association of Chairs of Departments of Psychiatry, of the American Psychiatric Association, of the Pacific Rim College of Psychiatrists. Together we hope that we continue to enrich the work of the Division and address the needs and aspirations of its members. The College has a very significant presence this year at the annual meeting of the American Psychiatric Association (APA). The meeting is taking place at the Javits Center in New York city, between the 5th and 9th of May. Please mark your diaries! Saturday May 05th, 8:00am–11:00am, Room 1A14 (First Level), Javits Center, 655 West 34th Street, New York Session Title: Body-Behavior-Brain Interactions in Psychosis (Session ID: 2017) Chair/presenter: Professor Sophia Frangou, (Icahn School of Medicine at Mount Sinai) Chair/presenter: Matcheri S. Keshavan (Harvard Medical School) Presenter: Christoph U. Correll (Donald and Barbara Zucker School of Medicine at Hofstra/Northwell) Presenter: Professor Swaran Singh (University of Warwick, UK) The presentations of this symposium summarize the current knowledge about the nature and prevalence of metabolic and glycemic dysregulation in psychosis, its association to medication, its effect on neuroimaging phenotypes and its implication for care planning and service provision. -
Focus on Caspase 1, Inducible Nitric Oxide Synthase, and Interferon-Gamma
Molecular Neurobiology https://doi.org/10.1007/s12035-018-1359-3 Neuroimmunomodulation in Major Depressive Disorder: Focus on Caspase 1, Inducible Nitric Oxide Synthase, and Interferon-Gamma Antonio Inserra1,2,3 & Claudio Alberto Mastronardi4,5 & Geraint Rogers6,7 & Julio Licinio8,9 & Ma-Li Wong1,2,9 Received: 29 April 2018 /Accepted: 19 September 2018 # The Author(s) 2018 Abstract Major depressive disorder (MDD) is one of the leading causes of disability worldwide, and its incidence is expected to increase. Despite tremendous efforts to understand its underlying biological mechanisms, MDD pathophysiology remains elusive and pharmacotherapy outcomes are still far from ideal. Low-grade chronic inflammation seems to play a key role in mediating the interface between psychological stress, depressive symptomatology, altered intestinal microbiology, and MDD onset. We review the available pre-clinical and clinical evidence of an involvement of pro-inflammatory pathways in the pathogenesis, treatment, and remission of MDD. We focus on caspase 1, inducible nitric oxide synthase, and interferon gamma, three inflammatory systems dysregulated in MDD. Treatment strategies aiming at targeting such pathways alone or in combination with classical therapies could prove valuable in MDD. Further studies are needed to assess the safety and efficacy of immune modulation in MDD and other psychiatric disorders with neuroinflammatory components. Keywords Major depressive disorder . MDD . Inflammation . Neuroinflammation . Caspase 1 . Inflammasome . T-helper 1 (Th1) . Interleukin 1 . Inducible nitric oxide synthase . Interferon gamma . Gut microbiome Introduction describe the elusive pathophysiology of MDD, including the monoamine hypothesis, the neurotrophic hypothesis, the gluta- Major depressive disorder (MDD) is a psychiatric disorder with mate hypothesis, the cytokine (or macrophage) hypothesis, and significant morbidity, mortality, disability, and economic bur- the microbiota-inflammasome hypothesis [8–13]. -
Telomere Length As a Predictor of Emotional Processing in the Brain
King’s Research Portal DOI: 10.1002/hbm.24487 Document Version Publisher's PDF, also known as Version of record Link to publication record in King's Research Portal Citation for published version (APA): Powell, T. R., De Jong, S., Breen, G., Lewis, C. M., & Dima, D. (2018). Telomere length as a predictor of emotional processing in the brain. Human Brain Mapping. https://doi.org/10.1002/hbm.24487 Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. And where the final published version is provided on the Research Portal, if citing you are again advised to check the publisher's website for any subsequent corrections. General rights Copyright and moral rights for the publications made accessible in the Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognize and abide by the legal requirements associated with these rights. •Users may download and print one copy of any publication from the Research Portal for the purpose of private study or research. •You may not further distribute the material or use it for any profit-making activity or commercial gain •You may freely distribute the URL identifying the publication in the Research Portal Take down policy If you believe that this document breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. -
FEAM Statement on Mental Health Policy Issues
FEAM Statement on Mental Health Policy Issues Statement November 2010 The Federation of the European Academies of Medicine (FEAM) FEAM was founded in 1993 in Brussels with the objective of promoting cooperation between the national Academies of Medicine and of extending to the political and administrative authorities of the European Union the advisory role that the Academies exercise in their own countries on matters concerning medicine and public health. As an umbrella organisation, it brings together national Academies of thirteen European member states (Austria, Belgium, Czech Republic, France, Germany, Greece, Hungary, Italy, Portugal, the Netherlands, Romania, Spain and the United Kingdom) and aims to reflect the European diversity by seeking the involvement of additional Academies and experts in its scientific activities and by collaborating with other European-wide networks on scientific matters of common interest. Published by Psychiatrické centrum Praha - Prague Psychiatric Center 2010 ISBN: 978-80-87142-11-0 © Federation of the European Academies of Medicine FEAM Statement on Mental Health Policy Issues A FEAM Statement November 2010 Content Summary 4 1. Introduction 5 2. Health and socio-economic impact of mental ill-health in the EU: what is the size of the problem? 6 3. EU mental health policy at the crossroads 8 4. What should be covered in a broader mental health strategy? 9 5. Conclusions 18 6. References 19 Appendix: FEAM procedures and contributing individuals 21 This Statement was endorsed by the FEAM member Academies 22 Acknowledgements 23 3 Summary The high burden of mental illness has been Our recommendations focus on the needs relatively neglected in EU policy. -
2017 Annual Meeting Guide
#APAAM17 psychiatry.org/ annualmeeting to the 2017 Annual Meeting Prevention Through Partnerships About This Guide psychiatry.org/annualmeeting In this book, you will find three sections: Program, New Research and the Exhibits Guide. Use these sections to navigate the 2017 Annual Meeting and experience all the meeting has to offer. Located within the Program, you will find a description of the various scientific session formats along with a log where you can record your daily attendance for the purpose of obtaining CME credit for your activities. The Program is first organized by day, then by session start time, with formats and sessions listed alphabetically under those times. Individual meeting days and program tracks are color- coded to make navigating the Program simple and easy. The New Research section lists the posters that will be presented at this meeting, organized numerically by session/day. There is a topic index at the end of the New Research section to assist you in finding the posters most interesting to you. The Exhibits Guide contains an acknowledgement to exhibitors for sponsorships, a list of the exhibitors and a floor plan of the Exhibit Hall, along with information about the Product Theaters, Therapeutic Updates, Career Fair, and Publishers Book Fair. Use this guide and the included exhibitor and author/presenter indices to navigate the exhibit hall and find precisely the booth you’re looking for. If you have any questions about this book or the scientific program, please feel free to stop by the Education Center, Ballroom 20 Foyer, Upper Level, San Diego Convention Center, and a member of the APA Administration will be happy to assist you. -
Two Thousand and Eighteen
two thousand and eighteen Mission The mission of AACAP is to promote the healthy development of children, adolescents, and families through advocacy, education, and research, and to meet the professional needs of child and adolescent psychiatrists throughout their careers. Table of Contents AACAP Catchers in the Rye Awards AACAP Catchers in the Rye Humanitarian Award .....................................................................7 AACAP Assembly Catchers in the Rye Award to an Individual ..................................................8 AACAP Assembly Catchers in the Rye Award to an AACAP Component .................................9 AACAP Assembly Catchers in the Rye Award to a Regional Organization ...............................10 AACAP Distinguished Member Awards AACAP Virginia Q. Anthony Outstanding Woman Leader Award ..........................................11 AACAP Cancro Academic Leadership Award ...........................................................................12 AACAP Elaine Schlosser Lewis Award for Research on Attention-Deficit Disorder .................13 AACAP Irving Philips, MD, Award for Prevention ...................................................................14 AACAP Norbert and Charlotte Rieger Psychodynamic Psychotherapy Award .........................15 AACAP Norbert and Charlotte Rieger Award for Scientific Achievement ................................16 AACAP Norbert and Charlotte Rieger Service Program Award for Excellence .........................17 AACAP Jeanne Spurlock, MD, Lecture and Award