SHORT COMMUNICATION ARTICLE Dipankar et.al / UJPSR / 3 (2), 2017, 33-37 Department of Pharmacy e ISSN: 2454-3764 Print ISSN: 2454-3756 DOI: 10.21276/UJPSR.2017.03.02.93 OROPOUCHE: A NEW HEADACHE FOR MEDICAL SCIENCE Dipankar Kumar Bhagat*, Sourav Mohanto, Dr. Shubhrajit Mantry Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, Sikkim, INDIA ARTICLE INFO: Abstract Article history: Oropouche virus (OROV) is an important cause of arboviral Received: illness in Latin American countries, more specifically in the 19 August 2017 Amazon region of Brazil, Venezuela and Peru, as well as in Received in revised form: other countries such as Panama. In the past decades, the 05 September 2017 clinical, epidemiological, pathological, and molecular aspects Accepted: 12 November 2017 of OROV have been published and provide the basis for a better understanding of this important human pathogen. Here, Available online: 10 December 2017 we describe the milestones in a comprehensive review of OROV epidemiology, pathogenesis, and molecular biology, Corresponding Author: including a description of the first isolation of the virus, the Dipankar Kumar Bhagat outbreaks during the past six decades, clinical aspects of OROV infection, diagnostic methods, genome and genetic Himalayan Pharmacy Institute traits, evolution, and viral dispersal. Majhitar, Sikkim, 737136, INDIA Key words Email:
[email protected] OROV, Human Pathogen, Panama Phone: +91-7319556801 INTRODUCTION Oropouche virus (OROV) is one of the most is the causative agent of Oropouche fever, a febrile common arboviruses that infect humans in Brazil. arboviral illness that is frequently associated with It is estimated that since the first isolation of the the Brazilian–Amazon region.