Anti-SESTD1 Monoclonal Antibody, Clone 3F8 (DCABH-3491) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-SESTD1 monoclonal antibody, clone 3F8 (DCABH-3491) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to Solo

Antigen Description May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.

Immunogen Recombinant full length Human Solo (amino acids 1-696) produced in HEK293T cells.

Isotype IgG1

Source/Host Mouse

Species Reactivity Mouse, Human

Clone 3F8

Purity Protein G purified

Purification This antibody is purified from mouse ascites fluids by affinity chromatography.

Conjugate Unconjugated

Applications WB, IHC-P, ICC/IF

Positive Control HEK293T cell lysate transfected with pCMV6-ENTRY Solo cDNA; COS7 cells transiently transfected with pCMV6-ENTRY Solo cDNA; Human colon adenocarcinoma, lung carcinoma, ovary adenocarcinoma, endometrium, endometrium adenocarcinoma, kidney and tonsil tissues

Format Liquid

Size 100 μl

Buffer pH: 7.30; Preservative: 0.02% Sodium azide; Constituents: 48% PBS, 50% Glycerol, 1% BSA

Preservative 0.02% Sodium Azide

Storage store at -20°C. Avoid repeated freeze / thaw cycles.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

GENE INFORMATION

Gene Name SESTD1 SEC14 and spectrin domains 1 [ Homo sapiens ]

Official Symbol SESTD1

Synonyms SESTD1; SEC14 and spectrin domains 1; SEC14 domain and spectrin repeat-containing protein 1; DKFZp434O0515; Solo; protein Solo; huntingtin-interacting protein-like protein; SOLO;

Entrez Gene ID 91404

Protein Refseq NP_835224

UniProt ID B3KTX3

Chromosome Location 2q31.3

Function NOT 1-phosphatidylinositol binding; phosphatidic acid binding; NOT phosphatidylcholine binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4,

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]