Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000007245Cyc: Xylella fastidiosa Temecula1 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari a metal cation acetate sn-glycerol 3-phosphate

RS03905 RS07795 RS02885 ActP UgpC

acetate sn-glycerol a metal 3-phosphate cation

Nucleoside and Nucleotide Degradation RS04665 Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Cell Structure Biosynthesis Other Biosynthesis Aminoacyl-tRNA Charging a nascent peptidoglycan an electron- a ribonucleoside a [protein]-L- a (7Z,10Z,13Z inosine 5'- quinoxaline-2- + a cis,cis-delta19,37-3- a 3-oxoicosanoyl- [2Fe-2S] iron-sulfur cluster biosynthesis UTP and CTP dephosphorylation I γ a palmitoleoyl-[acp] a malonyl-[acp] NADH H 2',3'-cyclic citrate β superpathay of heme b ubiquinol-8 biosynthesis superpathway of coenzyme A biosynthesis I (bacteria) Kdo transfer to lipid IV II TCA cycle TCA cycle I (prokaryotic) phosphate with (L-alanyl- -D- aryl-carrier protein transfer quinone hydroxy-C56:2-[acp] -isoaspartate [acp] ,16Z,19Z)-3- biotin ATP superpathway of tetrahydrofolate biosynthesis flavin biosynthesis I (bacteria and plants) superpathway of thiamine diphosphate biosynthesis II A tRNA charging lipid II (meso carboxyl adenylate NADH-quinone phosphate bifunctional protein-L- F0F1 ATP 8-amino-7- glutamyl-meso-2,6- acyl carrier beta-ketoacyl- 3-oxoacyl-ACP 3-oxoacyl-ACP oxodocosa- + + biosynthesis from glutamate (prokaryotic) degradation UTP diaminopimelate multifunctional CCA H H oxononanoate diaminopimeloyl- oxidoreductase aconitate hydratase reductase FabG: isoaspartate O- 7,10,13,16,19- bifunctional synthase L-cysteine desulfurase all-trans- 3-methyl-2- a 5,10- CMP-Kdo lipid IV oxaloacetate containing) protein: [acyl-carrier- tRNA nucleotidyl reductase 3-oxoacyl-ACP A biosynthesis I arginine-- D-alanyl-D-alanine) monofunctional subunit H: 2/2-methylisocitrate methyltransferase: pentaenoyl-[acp] biotin-- 4-hydroxybenzoate octaprenyl oxobutanoate methylenetetrahydrofolate a ThiS sulfur- cys 3-deoxy-D-manno- arg IMP PD_RS07910 protein] transferase/2'3'-cyclic PD_RS00755 FabG: reductase GTP GTP glu tRNA ligase: CTP pentapeptide biosynthetic PD_RS01370 dehydratase: PD_RS09635 [acetyl-CoA- cysteine diphosphate carrier protein octulosonic acid IMP acyl carrier synthase II: phosphodiesterase/ 3-oxoacyl-ACP PD_RS00755 FabG: 4-hydroxybenzoate 3-methyl-2-oxobutanoate a malonyl-[acp] PD_RS00620 an L-arginyl- synthetase: pyrG peptidoglycan PD_RS01250 carboxylase] desulfurase: cysteine transferase: dehydrogenase: a nascent peptidoglycan protein: PD_RS07905 quinone 2'nucleotidase/ reductase protein-L- 3-oxoacyl- PD_RS00755 H + RS00050 H + GTP octaprenyltransferase: hydroxymethyltransferase: malonyl-[acyl- Arg transglycosylase: GTP desulfurase: [tRNA ] malate:quinone UMP γ oxidoreductase: aconitate hydratase FabG: fabG isoaspartate O- synthetase/ PD_RS03605 an L-glutamyl- PD_RS00260 PD_RS00985 PD_RS00435 Arg PD_RS07650 CTP with (L-alanyl- -D- PD_RS10000 [+ 2 anisozymes] (11Z)-3- phosphatase: ACP 3-oxoacyl- cyclohydrolase cyclohydrolase- 3-octaprenyl-4- asp carrier protein] O- a tRNA oxidoreductase: di-trans,octa-cis PD_RS05685 a quinoxaline-2- PD_RS08575 a cis,cis-delta19,37- methyltransferase: biotin operon Glu PD_RS03605 α-Kdo-(2->6)-lipid IV malate XMP 5'-nucleotidase PD_RS03130 AcnA: PD_RS01235 reductase 2: PD_RS04255 [tRNA ] A methyltransferase glutamyl-meso-2,6- acyl-carrier protein oxooctadec- ACP an S-sulfanyl-[L- I FolE2: hydroxybenzoate a carboxy- an [L-cysteine PD_RS09250 -undecaprenyl AMP carboxyl-[aryl- an electron- + repressor: 2,5-diamino-6- 2-dehydropantoate dehydrogenase: citrate synthase: SurE: diaminopimeloyl- NAD a ribonucleoside D-threo-isocitrate 3-oxo-C56:2-[acp] βPD_RS10395 FabG: fabG cysteine desulfurase] PD_RS04070 glutamyl-tRNA aspartate 1- adenylated-[ThiS desulfurase]-S- D-glyceraldehyde 3-deoxy-D-manno- BioC: PD_RS04060 diphosphate carrier protein] 11-enoyl-[acp] transfer quinol a protein L- - a (3R)-3- a (3R,7Z,10reductaseZ PD_RS05625 (5-phospho-D- a malonyl-[acp] PD_RS02565 PD_RS03890 5'-nucleotidase PD_RS09630 D-alanyl-D-alanine) 3'-phosphate H + RS01890 H + reductase: decarboxylase: sulfur-carrier protein] sulfanyl-L-cysteine 3-phosphate octulosonic isoaspartate hydroxyicosanoyl- ,13Z,16Z,19ZFabG:)-3- fabG biotinyl-5'- GTP ribosylamino) methyl ester SurE: CMP pentapeptide α PD_RS10685 PD_RS00995 acid kinase: 5'-nucleotidase: -methyl ester [acp] hydroxydocosa- adenylate cyclohydrolase pyrimidin- 1-deoxy-D- beta-ketoacyl- cysteine-- (S)-malate citrate PD_RS09630 PD_RS04100 (S)-4-amino-5- 2-octaprenylphenol gly cysteine PD_RS06390 cys 5'-nucleotidase 7,10,13,16,19- an S-sulfanyl-[cysteine I FolE: 4(3H)-one β xylulose-5- [acyl-carrier- tRNA ligase: 5'-nucleotidase: (R)-pantoate -alanine desulfurase: 4-O-phospho-α- aconitate hydratase uridine SurE: pentaenoyl-[acp] desulfurase]-[disordered- PD_RS04285 bifunctional oxopentanoate phosphate protein] PD_RS01535 an L-cysteinyl- PD_RS04100 citrate RS01410 citrate 7,8- PD_RS03605 Kdo-(2->6)-lipid IV AcnA: PD_RS01235 PD_RS09630 form scaffold diaminohydroxyphosphoribosylaminopyrimidine glutamate-1- synthase: A synthase II: [tRNA Cys ] dihydroneopterin Cys bifunctional 5'-nucleotidase: undecaprenyl- guanosine a (7Z)-3- an [amino group protein] complex deaminase/5-amino-6-(5-phosphoribosylamino) semialdehyde pantoate--beta- PD_RS06845 PD_RS07905 a tRNA xanthosine a ring-opened 7- 3-(all-trans-heptaprenyl) a (4Z)-hexadec- a cis,cis-delta15,33-3- 3'-triphosphate 3-(all-trans a thiocarboxy- fumarate hydratase: aconitate hydratase PD_RS04100 diphospho-N- a malonyl-[acp] 2',3'-cyclic a 3-oxodocosanoyl-[acp] ethanol oxohexacos- carrier protein]- a protein [cysteine desulfurase]-S- uracil reductase RibD: PD_RS09225 2,1- alanine ligase: 1-deoxy-D-xylulose methylguanine in DNA benzene-1,2-diol 4-enoyl-[acp] hydroxy C52:2-[acp] 5-amino-6-(5- -octaprenyl) 2-iminoacetate [ThiS-Protein] [+ 2 isozymes] PD_RS04900 2/2-methylisocitrate S-methyl-5'- acetylmuramoyl- UDP-N-acetyl- formamidopyrimidine- bifunctional 3- monophosphate NAD(P)- 7-enoyl-[acp] C-terminal-γ- sulfanylcysteine:[acceptor aminomutase: PD_RS00990 AIR 5-phosphate cytidine beta-ketoacyl- multifunctional CCA 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP ATP- protein]-cysteine phospho-D- PD_RS07060 benzene-1,2-diol a 3-oxoglutaryl- class II fumarate dehydratase: thioadenosine L-alanyl-γ-D- α-D-glucosamine DNA glycosylase: demethylubiquinone 3- [acyl-carrier- reductase FabG: reductase FabG: dependent alcohol reductase (L-glutamate 5- bifunctional 3- hydratase: undecaprenyldiphospho- tRNA nucleotidyl dependent sulfurtransferase: 7,8- ribosylamino)uracil thiazole [acp] methyl ester PD_RS01250 degradation III glutamyl-L-lysyl- PD_RS00295 O-methyltransferase/2- protein] PD_RS00755 PD_RS00755 dehydrogenase: FabG: semialdehyde-2-N-acetyl- demethylubiquinone 3- phosphomethylpyrimidine glutamine-- PD_RS03980 muramoylpentapeptide beta-N- transferase/2'3'-cyclic Clp protease PD_RS03605 dihydroneopterin bifunctional 5-aminolevulinate (R)-pantothenate synthase: 3-oxoacyl-ACP gln S-methyl-5'- D-alanyl-D-alanine formamidopyrimidine- octaprenyl-6-hydroxy synthase II: PD_RS02215 PD_RS00755 yl)-L-glutamategamma- a [cysteine desulfurase]- O-methyltransferase/2- synthase: PD_RS04710 tRNA ligase: fumarate cis-aconitate xanthine ditrans,octacisacetylglucosaminyltransferase:- phosphodiesterase/ 3-oxoacyl-ACP 3-oxoacyl-ACP proteolytic 3'-phosphate diaminohydroxyphosphoribosylaminopyrimidine D-ribulose PD_RS09945 reductase thioadenosine DNA glycosylase: phenol methylase: PD_RS07905 NAD(P)- glutamyl- S-sulfanyl-[disordered- porphobilinogen octaprenyl-6-hydroxy pantothenate PD_RS03040 an L-glutaminyl- S-methyl-5'- undecaprenyldiphospho-PD_RS09890 2'nucleotidase/ reductase reductase 3-oxoacyl- subunit: deaminase/5-amino-6-(5-phosphoribosylamino) 5-phosphate HMP-P FabG: aconitate hydratase PD_RS00740 PD_RS07845 dependent alcohol phosphate synthase: kinase: Gln thioadenosine N-acetyl-(N-acetyl-β-D- 2,6-diamino-4- [+ 2 isozymes]a (6Z)-3- phosphatase: FabG: fabG FabG: fabG ACP an [amino group PD_RS02465 form scaffold uracil reductase RibD: PD_RS09225 phenol methylase: 2-[(2R,5Z)-2-carboxy- [tRNA ] succinate AcnA: PD_RS01235 UDP an apurinic site 2-methoxy-6-(all-trans a (3R)-3- a cis,cis-delta15,33- dehydrogenase: reductase: 5-amino-6-(5- 3,4-dihydroxy- PD_RS07040 PD_RS05630 superpathway of thiamine diphosphate biosynthesis I PD_RS00755 a tRNA Gln deaminase: glucosaminyl)muramoyl- hydroxy-5-(N-methyl) acyl-carrier protein oxooctadec- PD_RS03130 reductase carrier protein]- a peptide protein] complex PD_RS07845 bifunctional 4-methylthiazol-5(2H)- dehydrogenase: bifunctional -heptaprenyl)phenol 3-oxo-C52:2-[acp] PD_RS01570 cysteine 2-butanone- 2-methoxy- 3-oxoacyl- PD_RS07850 L-alanyl-γ-D-glutamyl-L- within DNA formamidopyrimidine 6-enoyl-[acp] hydroxydocosanoyl-[acp] PD_RS07425 FabG: fabG C-terminal-γ- 7,8- phospho-D- (R)-4'- hydroxymethylpyrimidine ylidene]ethyl phosphate PD_RS01845 aconitate hydratase S-methyl-5'- 3'-GMP a (3R,7Z)-3- desulfurase: chorismate 4-phosphate porphobilinogen 6-(all-trans- ACP urate lysyl-D-alanyl-D-alanine acetaldehyde (5-phospho- dihydroneopterin ribitylamino)uracil phosphopantothenate kinase/ PD_RS01855 2/2-methylisocitrate thioinosine hydroxyhexacos- PD_RS03605 synthase: octaprenyl)phenol cys reductase L-glutamyl)- dihydroneopterin bifunctional phosphomethylpyrimidine PD_RS01860 dehydratase: S-methyl-5'- 7-enoyl-[acp] an S-sulfanyl-[cysteine aminodeoxychorismate/ PD_RS09215 hydroxymethylbilane 2-octaprenyl-6- FabG: fabG L-glutamate aldolase: phosphopantothenoylcysteine kinase: PD_RS08065 cysteine PD_RS01250 thioinosine desulfurase]-S- anthranilate 1-deoxy-L- synthase: PD_RS06075 methoxyphenyl 2-(2-carboxy-4- a (3R)-3- glu sulfanyl-[disordered- PD_RS08630 synthase component decarboxylase/ desulfurase: phosphorylase: ARP glycero-tetrulose hydroxylase: HMP-PP methylthiazol-5- hydroxyglutaryl- form scaffold 6-(hydroxymethyl) II: PD_RS11720 preuroporphyrinogen phosphopantothenate--cysteine PD_RS03605 an L-glutamyl- succinate D-threo-isocitrate Carboxylate PD_RS07295 DNA combined with 3-(all-trans- adenosine a [pyruvate a (5Z)-3- 4-phosphate PD_RS09740 yl)ethyl phosphate [acp] methyl ester N 6 -dimethylallyladenosine 37 a sulfurated an L-phenylalanyl- an N-terminal a (9Z)-3-oxo- a [protein]- ligase CoaBC: PD_RS00630 an [L-cysteine Glu NADP-dependent exogenous DNA to form nonaprenyl) 2',3'-cyclic a 3-oxodocosanoyl-[acp] an aldehyde oxotetracos- protein] complex -7,8-dihydropterin aminodeoxychorismate 2-methoxy-6-all [tRNA ] Degradation Phe dehydrogenase L-histidine [cysteine desulfurase]-S- a ThiS sulfur- desulfurase]-S- glu in tRNA [sulfur carrier] [tRNA ] arginyl-[protein] octadec-9-enoyl-[acp] (R)-4'- a tRNA isocitrate 5-MTR-1-P a recombinational junction benzene-1,2-diol monophosphate NAD(P)- E2 protein] N 6 5-enoyl-[acp] PAS domain- sulfanylcysteine:[acceptor 2-amino-4-hydroxy-6- synthase, component 6,7-dimethyl-8- trans-octaprenyl- thiamine carrier protein succinyl-CoA succinate Holliday junction leucyl/ bifunctional 3- multifunctional CCA 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP phosphopantothenoyl- sulfanyl-L-cysteine dehydrogenase: acetate dependent alcohol -dihydrolipoyl- containing protein]-cysteine hydroxymethyldihydropteridine I: PD_RS07900 ribityllumazine 1,4-benzoquinol phosphate cysteine ligase subunit dehydrogenase, resolvase RuvX: phenylalanyl- demethylubiquinone 3- tRNA nucleotidyl reductase FabG: reductase reductase 2-octaprenyl- L-cysteine a (2E)- PD_RS10850 conversion dehydrogenase: L-lysine dihydrolipoyl sensor sulfurtransferase: diphosphokinase: PD_RS03525 4-amino-4- synthase: synthase: desulfurase: beta: PD_RS10225 hydrophobic PD_RS06750 tRNA--protein O-methyltransferase/2- transferase/2'3'-cyclic PD_RS00755 FabG: fabG FabG: uroporphyrinogen-III 6-methoxy-1,4- bifunctional enoylglutaryl- to acetyl-CoA PD_RS07425 dehydrogenase: histidine PD_RS03605 2-amino-4-hydroxy-6- deoxychorismate PD_RS09210 PD_RS08870 PD_RS03605 membrane crossover junction transferase: octaprenyl-6-hydroxy phosphodiesterase/ 3-oxoacyl-ACP 3-oxoacyl-ACP PD_RS00755 a [cysteine benzoquinone phosphopantothenoylcysteine D-glyceraldehyde [acp] methyl ester PD_RS09600 kinase: hydroxymethyldihydropteridine uroporphyrinogen a carboxy- a [ThiI sulfur- isoleucine-- acetate pyrimidine deoxyribonucleotides anchor protein: endodeoxyribonuclease PD_RS03475 phenol methylase: 2'nucleotidase/ reductase reductase FabG: NAD(P)- 3-oxoacyl- desulfurase]-(S- methylase: decarboxylase/ 3-phosphate ile L-phenylalanyl-L- dihydrolipoyl PD_RS09655 6,7-dimethyl-8-(1- decarboxylase: tRNA ligase: acetyl- PD_RS01850 6 Phe PD_RS07845 FabG: fabG PD_RS00755 dependent alcohol sulfanyl) -[disordered- diphosphokinase: PD_RS00980 phosphopantothenate--cysteine thiamine phosphate adenylated-[ThiS carrier protein]-S- dephosphorylation 2-methylsulfanyl-N - resolution of recombinationalRuvC: PD_RS04625 a tRNA 2-methoxy- phosphatase: dehydrogenase: ACP a [protein]- 2 PD_RS03670 1-deoxy-D- an unsulfurated arginyl-[protein] a (3R)-3- a (3R,9Z)-3-hydroxy- (7,8-dihydropterin- D-ribityl)lumazine PD_RS03020 sulfur-carrier protein] sulfanyl-L-cysteine PD_RS07595 coenzyme A 37 6-(all-trans- PD_RS03130 dehydrogenase: a [pyruvate reductase N-phospho- form scaffold 6-methoxy-3- ligase CoaBC: PD_RS00630 tyr an L-isoleucyl- nucleoside triphosphate met 5'-deoxyadenosine dimethylallyladenosine junction formation PD_RS03945 AIR xylulose-5- Ile succinyl-CoA 2-oxoglutarate [sulfur carrier] hydroxydocosanoyl-[acp] octadec-9-enoyl-[acp] dehydrogenase 6-yl)methyl 4-aminobenzoate riboflavin thiamine- a glutaryl-[acp] [tRNA ] synthetase: pyrophosphohydrolase: in tRNA of two intact strands nonaprenyl)phenol 3'-AMP PD_RS02215 FabG: fabG L-histidine protein] complex coproporphyrinogen III methyl-2-all- 6 a (3R,5Z)-3- phosphate Ile E2 protein] N diphosphate synthase: 4'-phosphopantetheine phosphate methyl ester a tRNA PD_RS06860 PD_RS00810 an alcohol hydroxytetracos- trans-octaprenyl- phosphomethylpyrimidine synthase: acetyl-CoA dCTP dCMP -lipoyl-L-lysine PD_RS09220 kinase: 5-enoyl-[acp] coproporphyrinogen III 1,4-benzoquinol phosphopantetheine synthase: PD_RS04710 PD_RS06845 beta-ketoacyl- riboflavin oxidase: PD_RS00075 PD_RS09200 a thiocarboxy- [acyl-carrier- a [cysteine desulfurase]- adenylyltransferase: 2-iminoacetate 1-deoxy-D-xylulose dUTP diphosphatase: PD_RS01475 HMP-P [ThiS-Protein] 5-phosphate protein] a (2R)-2-hydroxy a 3-(all-trans an [apo BCAA an (11Z)-3- [scaffold protein- 7,8- polyisoprenoid biosynthesis (E. coli) bifunctional protoporphyrinogen IX thiamine diphosphate 2-oxoglutarate PD_RS00635 2-amino-6-[1-hydroxyethyl]- an L-phenylalanyl- an N-terminal a (7Z)-3-oxo- a cis,cis-delta19,31- a cis-delta19-3- synthase II: leu leucine-- even numbered -polyprenyl) a 3-oxohexacosanoyl-[acp] dehydrogenase oxooctadec- (2Fe-2S)] complex dihydropteroate riboflavin 3'-dephospho- bifunctional dehydrogenase 7-methyl-7,8-dihydropterin [tRNA Phe ] L-lysyl-[protein] hexadec-7-enoyl-[acp] 3-hydroxyC50:2-[acp] oxo-C38:1-[acp] IMP 3-demethylubiquinol-8 PD_RS07905 tRNA ligase: nucleoside triphosphate 2-amino-4-hydroxy-6- benzene-1,2-diol 6 CoA hydroxymethylpyrimidine thiazole E1 component: straight chain leucyl/ bifunctional 3- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP E2 protein] N 11-enoyl-[acp]3-oxoacyl-ACP bifunctional IPP kinase/FAD [+ 2 isozymes] PD_RS06470 an L-leucyl- pyrophosphohydrolase: hydroxymethyldihydropteridine 5'-nucleotidase kinase/ synthase: PD_RS03960 2,3,4-saturatedlong-chain phenylalanyl- demethylubiquinone 3- reductase FabG: reductase reductase FabG: reductase FabG: -dihydrolipoyl- reductase tetrahydrofolate synthetase: 3-demethylubiquinone- dephospho- Leu PD_RS00810 dihydrolipoyl SurE: PD_RS09945 a 3-oxopimeloyl- [tRNA ] diphosphokinase: PD_RS03525 fatty acid tRNA--protein O-methyltransferase/2- PD_RS00755 FabG: fabG PD_RS00755 PD_RS00755 L-lysine FabG: a [co-chaperone]- synthase/ PD_RS07600 8 3-O- CoA kinase: phosphomethylpyrimidine a tRNA Leu dUTP dUMP fatty acid-- dehydrogenase: PD_RS09630 protoporphyrin IX pyridoxal 5'-phosphate biosynthesis I kinase: PD_RS08065 [acp] methyl ester 2-amino-4-hydroxy-6- CoA ligase: transferase: octaprenyl-6-hydroxy 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP PD_RS00755 [scaffold protein- dihydrofolate methyltransferase: PD_RS10180 2-[(2R,5Z)-2-carboxy- a (R)-2-hydroxy PD_RS09600 5'-nucleotidase: FMN hydroxymethyldihydropteridine PD_RS01230 PD_RS03475 phenol methylase: reductase reductase FabG: reductase reductase (2Fe-2S)] complex synthase: PD_RS07845 4-methylthiazol-5(2H)- 3-oxoacyl-ACP Macromolecule Modification even numbered dihydrolipoyl 3-oxoacyl- PD_RS04100 ferrochelatase: coenzyme A D-erythrose HMP-PP diphosphokinase: PD_RS00980 Phe L-phenylalanyl- PD_RS04445 reductase 5-hydroxy-CTP 5-hydroxy-CMP [1-(2-amino-7-methyl-4-oxo- diphosphate AMP straight chain a tRNA a 2-methoxy-PD_RS07845 FabG: fabG PD_RS00755 FabG: fabG FabG: fabG ACP DMAPP bifunctional PD_RS08275 4-phosphate ylidene]ethyl phosphate L-lysyl-[protein] a (3R)-3- a (3R,7Z)-3-hydroxy- a cis,cis-delta19,31- a cis-delta19-3- dehydrogenase: inosine ubiquinol-8 FabG: 7,8-dihydro-3H-pteridin- 2,3,4-saturated 6-(all-trans- an [apo BCAA reductase 7,8-dihydrofolate riboflavin valine-- tRNA processing hydroxyhexacosanoyl-[acp] hexadec-7-enoyl-[acp] 3-oxo-C50:2-[acp] hydroxyC38:1-[acp] dehydrogenasePD_RS03945 monoglutamate farnesyl- thiamine PD_RS00755 val 6-yl)]ethyl diphosphate fatty acyl CoA polyprenyl)phenol a (3R,11Z)-3-FabG: fabG a [chaperone-ATP]- kinase/FAD thiamine salvage II protoheme tRNA ligase: E2 protein] N 6 phosphate hydroxyoctadec- [co-chaperone]- diphosphate synthetase: 3-oxoacyl- PD_RS00550 an L-valyl- a polycistronic -lipoyl-L-lysine synthase: 4-amino-2-methyl-5- 4-phospho- synthase: ACP Alcohol Degradation 11-enoyl-[acp] [scaffold protein- PD_RS07600 heme b biosynthesis [tRNA Val ] tRNA precursor 10 D-erythronate PD_RS08870 (2Fe-2S)] complex PD_RS07960 pyrimidinemethanol N -formyl-tetrahydrofolate biosynthesis II (anaerobic) reductase a tRNA Val a 7,8-dihydrofolate geranyl FAD bifunctional FabG: fabG glycerol a (6Z)-3- a 7,8-dihydro-8- α,ω-9Z- a (6S)-5- a (3R,5Z)-3-hydroxy- a cis,cis-delta17,29- a cis-delta17-3- diphosphate hydroxymethylpyrimidine uroporphyrinogen-III a (3R)-3- degradation I glu a 3-oxotetracosanoyl-[acp] butan-1-ol oxooctadec- dihydrofolate a tetrahydrofolate thiamine phosphate a tRNA precursor CTP ATP oxoguanine in DNA octadecenedioate formyltetrahydrofolate tetradec-5-enoyl-[acp] 3-hydroxyC48:2-[acp] oxo-C36:1-[acp] dGDP kinase/ uroporphyrinogen hydroxypimeloyl- formamidopyrimidine- long-chain NAD(P)- 6-enoyl-[acp] reductase: farnesyl- (3R)-3-hydroxy-2-oxo- a tRNA precursor a tRNA precursor with bifunctional 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP a [chaperone- phosphomethylpyrimidine decarboxylase: [acp] methyl ester Amino Acid Degradation glycerol multifunctional CCA tRNA DNA glycosylase: fatty acid-- dependent alcohol ribonucleoside- an [2Fe-2S] PD_RS07205 diphosphate 4 phosphooxybutanoate thiamine- alanine-- with a 5' extension a 5' extension and tetrahydrofolate reductase FabG: reductase reductase FabG: reductase FabG: reductase ADP]-[disordered- kinase: PD_RS08065 PD_RS03020 phosphate ala glycerol nucleotidyl transferase/2'3'- PD_RS00295 CoA ligase: dehydrogenase: diphosphate cluster protein synthase: phosphoserine coproporphyrinogen III tRNA ligase: and a long 3' trailer a short 3' extension synthase/ PD_RS00755 FabG: fabG PD_RS00755 PD_RS00755 FabG: form scaffold kinase: kinase: cyclic phosphodiesterase/ formamidopyrimidine- PD_RS01230 PD_RS02215 reductase: a tetrahydrofolate PD_RS07960 aminotransferase: PD_RS00510 an L-alanyl- ribonuclease glycine cleavage dihydrofolate 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP PD_RS00755 protein] complex HMP-P D-glyceraldehyde PD_RS09200 a (2E)- PD_RS06900 2'nucleotidase/ DNA glycosylase: ω-carboxy- PD_RS02510 PD_RS07180 Ala P protein reductase reductase FabG: reductase reductase NAD(P)- (2E,6E)-farnesyl pyruvate enoylpimeloyl- [tRNA ] sn-glycerol phosphatase: PD_RS03130 AMP diphosphate (9Z)-octadec- synthase: 3-oxoacyl- PD_RS02515 3-phosphate Ala a [glycine-cleavage complex PD_RS00740 diphosphate 5-(2-hydroxyethyl) bifunctional 4-phosphooxy- a tRNA ribonuclease D: component: 3-phosphate PD_RS04445 FabG: fabG PD_RS00755 FabG: fabG FabG: fabG dependent alcohol ACP thiamine diphosphate [acp] methyl ester ribonuclease D: 6 glycine a tRNA containing a 3' CCA end an apurinic site 7,8-dihydro- 9-enoyl-CoA GDP -4-methylthiazole hydroxymethylpyrimidine 1-deoxy-D- L-threonine ribonuclease PD_RS11260 H protein] N -lipoyl-L-lysine a (6S)-5- a (3R)-3- a (5Z)-3-oxo- a cis,cis-delta17,29- a cis-delta17-3- dehydrogenase: reductase dihydrofolate PD_RS10080 PD_RS10080 dehydrogenase within DNA 8-oxoguanine an [Fe-S cluster a [disordered- kinase/ xylulose-5- protoporphyrinogen IX PH: formyltetrahydrofolate hydroxytetracosanoyl-[acp] tetradec-5-enoyl-[acp] 3-oxo-C48:2-[acp] hydroxyC36:1-[acp] PD_RS07425 FabG: fabG ditrans,polycis- octaprenyl- reductase: 4-hydroxythreonine- a tRNA precursor with (aminomethyl- a (3R,6Z)-3- biosynthesis form [Fe-S] cluster phosphomethylpyrimidine phosphate PD_RS03755 glycine cleavage butan-1-al undecaprenyl- diphosphate PD_RS07205 4-phosphate a short 3' extension transferring): hydroxyoctadec- chaperone]-ATP scaffold protein] kinase: PD_RS08065 glycine cleavage synthase: system protein diphosphate synthase: 4-methyl-5-(2- dehydrogenase: a pimeloyl-[acp] asparagine-- PD_RS03225 DHAP 6-enoyl-[acp] a 7,8-dihydrofolate system proteina 5-methyltetrahydrofolate PD_RS06845 PD_RS09720 asn a tRNA precursor H: PD_RS00790 synthase PD_RS03250 phosphooxyethyl) HMP-PP lipoate biosynthesis methyl ester tRNA ligase: serine H: PD_RS00790 1-deoxy-D- 3-amino-1- with a 5' extension [+ 2 isozymes] glycine cleavage ((2E,6E)- thiazole protoporphyrin IX and incorporation PD_RS10315 an L-asparaginyl- ribonuclease 3-(all-trans all-trans- hydroxymethyltransferase: glyA xylulose 5- hydroxyacetone pimeloyl-[acyl- ribonuclease D: system protein undecaprenyldiphospho- a reduced a (5Z)-3- farnesyl- Asn PH: a nucleoside a cis,cis-delta13,31-3- a cis,cis-delta15,27- a cis-delta15-3- butan-1-ol NAD de novo biosynthesis NAD biosynthesis from 2- thymidylate 1-phosphate III (Bacillus) carrier protein] [tRNA ] PD_RS10080 a [glycine-cleavageH: PD_RS00790 N-acetylmuramoyl-L- electron-transfer ubiquinone-6 a small subunit of a ribonucleic acid -decaprenyl) oxododec- diphosphate octaprenyl thiamine phosphate ferrochelatase: tRNA Asn ribonuclease PD_RS03755 a [glycine-cleavage UDP-N-acetyl- ATP triphosphate hydroxy C50:2-[acp] 3-hydroxyC46:2-[acp] oxo-C34:1-[acp] dADP I (from aspartate) amino-3-carboxymuconate synthase: methyl ester complex H protein] N 6 - alanyl-γ-D-glutamyl-meso flavoprotein electron transfer molybdopterin synthase DNA- benzene-1,2-diolbifunctional 3- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP NAD(P)- 5-enoyl-[acp]3-oxoacyl- specific): diphosphate phosphate PD_RS08275 an octanoyl-[acp] P protein complex H protein] N 6 α-D-glucosamine ribonucleoside- semialdehyde PD_RS07210 esterase: aminomethyldihydrolipoyl- -2,6-diaminopimeloyl- molybdopterin- reductase FabG: reductase FabG: reductase FabG: dependent alcohol synthase: a (6S)-5- pyridoxine 5'- lipoyl(octanoyl) component: -dihydrolipoyl-L-lysine flavoprotein- directed RNA demethylubiquinone 3- ACP diphosphate 2-amino-3- PD_RS01750 PD_RS03105 D-alanyl-D-alanine undecaprenyldiphospho- synthase PD_RS00755 dehydrogenase: asp PD_RS08870 bifunctional formyltetrahydrofolate phosphate protoheme transferase L-lysine ubiquinone polymerase O-methyltransferase/2- PD_RS00755 PD_RS00755 reductase carboxymuconate- PD_RS11260 muramoylpentapeptide beta-N- adenylyltransferase PD_RS02215 reductase: di-trans,octa-cis methylenetetrahydrofolate methylenetetrahydrofolate 5-formyltetrahydrofolate synthase: LipB: oxidoreductase: subunit omega: octaprenyl-6-hydroxy 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP FabG: fabG PD_RS02510 L-aspartate oxidase: 6-semialdehyde a pimeloyl-[acp] aspartate-- NADH repair acetylglucosaminyltransferase: a carboxy-adenylatedMoeB: PD_RS08510 -undecaprenyl thiamine reductase [NAD(P) dehydrogenase/ cyclo-ligase: PD_RS00230 a [glycine-cleavagePD_RS02770 asp PD_RS02860an oxidized PD_RS03740 phenol methylase: reductase reductase reductase NAD(P)- 3-oxoacyl-ACP PD_RS02515 PD_RS04535 tRNA ligase: lipid II (PD_RS09890meso [small subunit of + PD_RS07845 FabG: fabG FabG: fabG FabG: fabG dependent alcohol 2-iminosuccinate diphosphate phosphate H]: PD_RS02160 methenyltetrahydrofolate PD_RS04165 complex H protein] 8-amino-7- UDP H ubiquinol-6 electron-transfer molybdopterin synthase] [+ 2 isozymes] 6-(all-trans- reductase ADP quinolinate 6 PD_RS04895 an L-aspartyl- glycine cleavage diaminopimelate containing) a cis,cis-delta13,31- a cis,cis-delta15,27- a cis-delta15-3- dehydrogenase: undecaprenyl- a 5,10- cyclohydrolase: PD_RS07655 a 5,10- pyridoxine N -octanoyl-L-lysine oxononanoate NADH flavoprotein a ribonucleic acid decaprenyl)-2- FabG: thiamine- [tRNA asp ] system protein 3-oxo-C50:2-[acp] 3-oxo-C46:2-[acp] hydroxyC34:1-[acp] PD_RS07425 quinolinate synthase diphosphatase: 5'-phosphate methoxy-phenol a (3R,5Z)-3-PD_RS00755 nicotinate- NAD salvage pathway I (PNC VI cycle) phosphate methylenetetrahydrofolate methenyltetrahydrofolate synthase: tRNA asp an uncharged tRNA H: PD_RS00790 NadA: PD_RS04540 nucleotide PD_RS05405 pyridoxamine PD_RS03110 butan-1-al hydroxydodec- di-trans,octa-cis kinase: bifunctional aminomethyltransferase: diphosphorylase PD_RS09200 methylenetetrahydrofolate 5'-phosphate a [lipoyl-carrier protein] 8-amino-7- 5-enoyl-[acp] quinolinate -undecaprenyl NAD + PD_RS00795 (carboxylating) oxidase: 6 phosphate thiamine dehydrogenase/ N -octanoyl-L-lysine oxononanoate : PD_RS04530 PD_RS03035 (R)-NADHX nicotinate-nucleotide folate transformations I methenyltetrahydrofolate γ a 2-methyl cytidine 2',3'-cyclic a (9Z)-3- diphosphate lipoyl synthase: tyrosine-- bifunctional α L-alanyl- -D-glutamyl- phosphoenol an [HPr]- a cis,cis-delta11,29-3- a cis,cis-delta21,39- a cis-delta13-3- an organic cyclohydrolase: PD_RS07655 tyr lipoprotein posttranslational UDP-N-acetyl- -D-muramate branched 2,3,4- monophosphate phytol oxooctacos- diphosphorylase NaMN PLP PD_RS02765 tRNA ligase: ADP- meso-diaminopimelate pyruvate L-histidine ATP H O hydroxy C48:2-[acp] 3-hydroxyC58:2-[acp] oxo-C32:1-[acp] molecule modification L-serine L-methionine degradation saturated fatty acid phosphoenolpyruvate- 2 multifunctional CCA NAD(P)- 9-enoyl-[acp] cytochrome (carboxylating) glutamine- a tetrahydrofolate 10 a [lipoyl-carrier UDP-N- long-chain 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP an N -formyltetrahydrofolate heme a biosynthesis PD_RS00710 an L-tyrosyl- dependent type I secretion tRNA nucleotidyl : PD_RS04530 nicotinate-nicotinamide dependent NAD+ 6 degradation I (to L-homocysteine) acetylmuramate:L-alanyl- -protein dependent alcohol P450: siroheme biosynthesis protein]-N -[(R)- Tyr a [prolipoprotein]- NAD(P)H- fatty acid-- reductase FabG: reductase FabG: reductase FabG: reductase superpathway of heme [tRNA ] phosphotransferase: system permease/ transferase/2'3'-cyclic dehydrogenase: PD_RS08875 nucleotide synthetase: dihydrolipoyl]-L-lysine Tyr L-cysteine gamma-D-glutamyl- CoA ligase: PD_RS00755 PD_RS00755 PD_RS00755 FabG: NaMN b biosynthesis from a tRNA hydrate ATPase: phosphodiesterase/ adenylyltransferase: nicotinate adenine dinucleotidePD_RS04370 NMN protoheme ser met meso-diaminopimelate PD_RS01230 PD_RS03290 PD_RS02215 PD_RS00755 cytochrome formyltetrahydrofolate uroporphyrinogen-III protoheme IX prolipoprotein dehydratase/ a 2-methyl an [HPr protein]- PD_RS07455 2'nucleotidase/ 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP PD_RS06485 uroporphyrinogen-III π nicotinate-nicotinamide deformylase: diacylglyceryl NAD(P)H- threonine/ S-adenosylmethionine ligase: PD_RS01180 N -phospho- pyruvate reductase reductase reductase NAD(P)- 3-oxoacyl- P450: met RS09575 met uroporphyrinogen III nicotinate-nicotinamide farnesyltransferase: UDP-N-acetyl-α-D-muramoyl-L-alanyl- branched H + phosphate ADP phosphatase: nicotinate adenine uroporphyrinogen-III serine AMP diphosphate L-histidine FabG: fabG FabG: fabG FabG: fabG dependent alcohol PD_RS08950 nucleotide methyltransferase: nucleotide PD_RS05450 PD_RS03120 transferase: hydrate synthase: PD_RS08815 γ-D-glutamyl-meso-2,6-diaminopimelate 2,3,4-saturated PD_RS03130 ACP dinucleotide uroporphyrinogen dehydratase: a cis,cis-delta11,29- a cis,cis-delta21,39- a cis-delta13-3- dehydrogenase: an alcohol adenylyltransferase: PD_RS05610 adenylyltransferase: ferroheme o tryptophan-- PD_RS07215 epimerase: SAM fatty acyl-CoA reductase decarboxylase: Trp 3'-cmp 3-oxo-C48:2-[acp] 3-oxo-C58:2-[acp] hydroxyC32:1-[acp] PD_RS07425 PD_RS06485 glutamine- a tRNA a [prolipoprotein]- PD_RS10060 2-aminoprop-PD_RS05500 a cis-delta9-3-FabG: fabG siroheme synthase: PD_RS06485 PD_RS03020 tRNA ligase: (S)-NADHX dependent glycine heme A synthase: S-1,2-diacyl-sn- 2-enoate phytenal hydroxyC28:1- PD_RS09755 10 coproporphyrinogen III PD_RS08675 nicotinate adenine dinucleotide NAD+ cleavage an N - an L-tryptophanyl- glyceryl-L-cysteine precorrin-1 NaMN nicotinamide PD_RS03115 Trp ATP- [acp] synthetase: system formyltetrahydrofolate [tRNA ] nicotinamidase: coproporphyrinogen III folate polyglutamylation dependent glutamine-dependent NAD+ PD_RS04370 protein H: a (6S)-5- ferroheme i trp lipoprotein uroporphyrinogen III PD_RS06925 oxidase: PD_RS00075 NADH-hydrate SAH synthetase: PD_RS04370 bifunctional signal a 3-methyl- 1915 uridine 2'3'-cyclic an (11Z)-3- α-Kdo8N- methyltransferase: PD_RS00790 formyltetrahydrofolate a pseudouridine a (7Z)-hexadec- a cis,cis-delta13,25- a cis-delta11-3- D-mannitol + dehydratase: 2-iminopropanoate a palmitoyl-[acp] a malonyl-[acp] branched 2,3,4- a malonyl-[acp] monophosphate a [protein] Ser/Thr oxo-icos-11- (2->6)-lipid IV NAD nicotinate methylenetetrahydrofolate heme A synthase: a tetrahydrofolate peptidase: in 23S rRNA A NAD + PD_RS05610 protoporphyrinogen IX PD_RS10060 7-enoyl-[acp] multifunctional CCA 3-hydroxyC44:2-[acp] oxo-C30:1-[acp] 3-deoxy- phosphoribosyltransferase: dehydrogenase/ 5-formyltetrahydrofolate PD_RS03115 PD_RS07590 adenosylhomocysteinase: beta-ketoacyl-[acyl- saturated fattylong-chain acid 23S rRNA 3-oxoacyl-ACP HPr kinase/ 3-oxoacyl-ACP 3-oxoacyl-ACP NAD(P)- enoyl-[acp]3-oxoacyl- PD_RS01690 (pseudouridine(1915)- tRNA nucleotidyl phosphorylase: dependent alcohol D-manno- precorrin-2 PD_RS02055 methenyltetrahydrofolate cyclo-ligase: serine threonine-- NADH carrier-protein] synthase fatty acid-- synthase III: reductase FabG: reductase FabG: ACP thioredoxin hydroxyferroheme i bifunctional thr an (S-diacyl- N(3))-methyltransferase transferase/2'3'-cyclic PD_RS03310 dehydrogenase: octulosonic nicotinate cyclohydrolase: PD_RS07655 PD_RS04165 hydroxymethyltransferase: glyA tRNA ligase: a lipoprotein II: PD_RS07905 CoA ligase: PD_RS05510 PD_RS00755 PD_RS00755 reductase pathway bifunctional tetrahydrofolate sn-glyceryl) RlmH: PD_RS09000 phosphodiesterase/ PD_RS02215 acid kinase: siroheme synthase: bifunctional PD_RS10145 an L-threonyl- signal peptide L-homocysteine [+ 2 isozymes] PD_RS01230 an N 3 - [+ 2 isozymes] serine/threonine 3-oxoacyl-ACP 3-oxoacyl-ACP FabG: fabG glutathione 10 synthase/ pyruvate a 3-methyl- a (9Z)-3-oxo- 2'nucleotidase/ PD_RS06390 PD_RS09755 methylenetetrahydrofolate an N - Thr -L-cysteinyl- 1915 protein kinase: NAD(P)- an oxidized biosynthesis methylenetetrahydrofolate a 5,10- protoporphyrin IX dihydrofolate a 5,10- [tRNA ] acyl-carrier protein a 3-oxooctadecanoyl-[acp] branched methylpseudouridine acyl-carrier protein octadec-9- reductase reductase 3-oxoacyl-ACP 4-O-phospho- dehydrogenase/ formyltetrahydrofolate Thr [apolipoprotein] phosphatase: thioredoxin thiamine serine dehydrogenase/ methenyltetrahydrofolate methylenetetrahydrofolate a tRNA diphosphate AMP in 23S rRNA enoyl-[acp] PD_RS01190 FabG: fabG FabG: fabG dependent alcohol reductase α-Kdo8N- sirohydrochlorin methenyltetrahydrofolate synthase: 2,3,4-saturated PD_RS03130 salvage I hydroxymethyltransferase: glyA methenyltetrahydrofolate glutathione- ferrochelatase: bifunctional a [protein] (L-serine/L- a cis,cis-delta13,25- a cis-delta11-3- dehydrogenase: FabG: (2->6)-lipid IV ferroheme a PD_RS04445 bifunctional fatty acyl-CoA A cys glu cyclohydrolase: PD_RS07655 cyclohydrolase: PD_RS07655 glutaredoxin PD_RS08275 tetrahydrofolate 3'-UMP threonine) phosphate 3-oxo-C44:2-[acp] hydroxyC30:1-[acp] PD_RS07425 siroheme synthase: tetrahydrofolate a peptide a (3R,11Z)-3-PD_RS00755 glutamate- thiamine redox reactions synthase/ an N-acyl-(S- L-phenylalanine degradation I (aerobic) aldehydo- thioredoxin- PD_RS09755 synthase/ hydroxy-icos- -cysteine protoheme dihydrofolate a tetrahydrofolate diacyl-sn-glyceryl) D-mannose disulfide glutathione dihydrofolate serine-- 11-enoyl-[acp] ligase: a 5,10- synthase: ser -L-cysteinyl- (6R)-4a-hydroxy- reductase: siroheme thiamine a 5-methyltetrahydrofolate synthase: tRNA ligase: γ PD_RS03410 methylenetetrahydrofolate lipoate biosynthesis NAD phosphorylation PD_RS04445 [lipoprotein] tetrahydrobiopterin 4a-hydroxytetrahydrobiopterin PD_RS03485 -L-glutamyl- phosphate PD_RS04445 PD_RS06965 an L-seryl- and incorporation I 10 a long-chain N-acetyl-D- N-acetyl-β-D-glucosamine- L-cysteine and dephosphorylation an N - ser dehydratase: PD_RS10475 a [lipoyl-carrier a reduced [tRNA ] a (3Z)-dec- hydrogencarbonate H + a cis,cis-delta11,23- a cis-delta21-3- thiamine- methylenetetrahydrofolate a 5,10- an acetyl-[acp] a malonyl-[acp] 2,3,4-saturated galactosamine a malonyl-[acp] 1,6-anhydro-N- protein]-N 6 -[(R) glutathione glutaredoxin formyltetrahydrofolate a tRNA ser 3-enoyl-[acp] 3-hydroxyC42:2-[acp] oxo-C40:1-[acp] AMP dIDP reductase [NAD(P) + methylenetetrahydrofolate fatty acid 6-phosphate β carbonate a reduced synthetase: phosphate an octanoyl-[acp] NAD beta-ketoacyl-[acyl- long-chain N-acetylglucosamine- 3-oxoacyl-ACP acetyl- -D-muramate 3-oxoacyl-ACP 3-oxoacyl-ACP -dihydrolipoyl]- H]: PD_RS02160 beta- dehydratase: 5'-nucleotidase nucleoside- thioredoxin PD_RS04395 geranyl kinase: acyl carrier lipoyl(octanoyl) glutaredoxin 3: queuosine biosynthesis carrier-protein] synthase fatty acid-- 6-phosphate synthase III: hexosaminidase: reductase FabG: reductase FabG: L-lysine dihydrolipoyl (6R)-L-erythro-5,6,7,8- L-erythro-7,8- PD_RS04075 SurE: diphosphate diphosphate PD_RS09200 protein activation transferase LipB: PD_RS10435 L-glutamine II: PD_RS07905 CoA ligase: deacetylase: PD_RS05510 PD_RS07305 PD_RS00755 PD_RS00755 dehydrogenase: glutathione alkaline tetrahydrobiopterin dihydrobiopterin degradation I carbonate PD_RS03945 PD_RS09630 kinase: biosynthesis thiamine a [lipoyl-carrier protein]PD_RS02770 NAD kinase: a protein with preQ [+ 2 isozymes] PD_RS01230 PD_RS03570 [+ 2 isozymes]a (5Z)-3- beta- 3-oxoacyl-ACP 3-oxoacyl-ACP phosphatase: proline-- 0 a long-chain D-galactosamine dehydratase: 5'-nucleotidase: PD_RS08545 diphosphate an apo acyl- 6 PD_RS04095 reduced L- pro NADPH-dependent 7- an acetoacetyl-[acp] acyl-carrier protein acetate acyl-carrier protein oxododec- reductase reductase dihydrolipoyl IPP N -octanoyl-L-lysine PD_RS07975 tRNA ligase: AMP diphosphate 2,3,4-saturated 6-phosphate hexosaminidase: PD_RS04100 carrier protein cysteine residues gln PD_RS09560 FabG: fabG FabG: fabG dehydrogenase: dITP farnesyl- 4'-phosphopantetheinyl PD_RS08595 cyano-7-deazaguanine fatty acyl CoA 5-enoyl-[acp] PD_RS09685 lipoyl synthase: an L-prolyl- CTP 1,6-anhydro-N- H O CO a cis,cis-delta11,23- a cis-delta21-3- a [lipoyl-carrierPD_RS09600 adenosine transferase: reductase QueF: GlcNAc 2 2 diphosphate PD_RS02765 [tRNA Pro ] β 3-oxo-C42:2-[acp] hydroxyC40:1-[acp] protein]-N 6 - + PD_RS07400 synthetase: acetyl- -muramate synthase: PD_RS04495 NADP a tRNA Pro L-glutamine a holo acyl- a [lipoyl-carrier protein]-N 6 - preQ pyrG lipoyl-L-lysine PD_RS07960 Metabolic Regulator 1 degradation II geranyl carrier protein [(R)-dihydrolipoyl]-L-lysine [+ 7 isozymes] Biosynthesis tRNA guanosine(34) diphosphate glu a [2-oxoglutarate- an N-acetyl-β- UDP-N-acetyl- ppGpp biosynthesis transglycosylase gln dehydrogenase a sulfurated an acyl-[acyl- a malonyl-[acp] decanoate a (5Z)-tetradec- a malonyl-[acp] α-D-muramoyl- D-glt a cis,cis-delta17,35- acetyl-CoA (R)-NADPHX SAM D-hexosaminide GMP IDP phenylalanine- Tgt: PD_RS00950 glutamate 6 carrier protein] 5-enoyl-[acp] beta- 3-hydroxyC54:2-[acp] E2 protein] N - [sulfur carrier] 3-oxoacyl-ACP long-chain fatty 3-oxoacyl-ACP L-alanine UDP-N- 3-oxoacyl-ACP acetyl-CoA bifunctional -tRNA ligase: a 7-aminomethyl-7- synthase hexosaminidase: 5'-nucleotidase nucleoside- pppGpp phe octanoyl-L-lysine lipoyl synthase: synthase III: acid--CoA ligase: synthase III: acetylmuramoyl- reductase FabG: carboxylase ADP-dependent PD_RS10120 deazaguanosine 34 in tRNA subunit beta: PD_RS07305 SurE: diphosphate PD_RS02765 PD_RS05510 PD_RS01230 PD_RS05510 L-alanine--D- PD_RS00755 carboxyltransferase NAD(P)H-hydrate Carbohydrate Biosynthesis bifunctional (p)ppGpp PD_RS10125 an L-phenylalanyl- PD_RS10880 L-aspartate a [2-oxoglutarate PD_RS09630 kinase: S-adenosylmethionine:tRNA an unsulfurated dehydrogenase [+ 2 isozymes] [+ 2 isozymes] beta- glutamate ligase: 3-oxoacyl-ACP subunit beta: dehydratase/ synthetase/guanosine- [tRNA Phe ] glu degradation I diphosphate AMP decanoyl-CoA a (7Z)-3-oxo- PD_RS08545 ribosyltransferase- 5'-deoxyadenosine met 6 hexosaminidase: PD_RS03575 NAD(P)H-hydrate 5'-nucleotidase: a tRNA Phe [sulfur carrier] E2 protein] N acyl-carrier protein a 3-oxoacyl-[acp] acyl-carrier protein hexadec-7- UDP-N-acetyl-PD_RS02145 reductase O-antigen building blocks biosynthesis (E. coli) 3',5'-bis(diphosphate) 3'- isomerase: PD_RS02930 PD_RS09685 epimerase: PD_RS04100 GDP-mannose biosynthesis -lipoyl-L-lysine enoyl-[acp] α-D-muramoyl-L- FabG: fabG [+ 3 isozymes] ITP α pyrophosphohydrolase: relA asp an N-acetyl-β- a cis,cis-delta17,35- PD_RS10060 guanosine Fatty Acid and Lipid Biosynthesis UDP-α-D- α-D- D-glucopyranose UDP- -D-glucose guanosine 3'- an epoxyqueuosine 34 in tRNA an alcohol alanyl-D-glutamate malonyl-CoA bifunctional (p)ppGpp aspartate/ L-glutamate D-hexosamine 3-oxo-C54:2-[acp] galactose glucopyranose 6-phosphate D-glucopyranose biosynthesis I diphosphate 5'- (S)-NADPHX glucose-6- synthetase/guanosine- guanosine-5'- tyrosine/aromatic degradation I palmitate biosynthesis 1-phosphate 6-phosphate D-glucopyranose triphosphate 3'- superpathway of (Kdo) -lipid A biosynthesis (Kdo) -lipid A glucose-1-phosphate phosphate glucose-6- 3',5'-bis(diphosphate) 3'- triphosphate,3'- methionine-- aminotransferase: 2 2 diphosphatase: met II (bacteria and plants) biosynthesis I UDP-Galf thymidylyltransferase: phosphate 6-phosphate pyrophosphohydrolase: tRNA ligase: isomerase: phosphomannomutase/ PD_RS08965 diphosphate PD_RS00145 glu a [pyruvate 34 PD_RS01110 isomerase: PD_RS08965 PD_RS08355 an L-methionyl- oxaloacetate a cis- sn-glycerol a (3Z)-dodec- a guanine a cis,cis-delta9,21-3- a ribonucleoside a [protein]-L- a (3R)-3- α-Kdo-(2-> dTDP-α-D-glucose PD_RS01000 phosphoglucomutase: phosphatase: a queuosine 34 in tRNA glutamate dehydrogenase a sulfurated linoleate a malonyl-[acp] queuine (S)-NADPHX carbonic acid an acetoacetyl-[acp] PD_RS01000 [elongator SAM in tRNA dGTP diphosphate methionine UDP-N-acetyl- α F6P PD_RS01130 PD_RS10410 6 vaccenoyl-[acp] 3-phosphate 3-enoyl-[acp] hydroxyC40:2-[acp] hydroxytetradecanoyl-[acp] 4)- -Kdo-(2- Met dehydrogenase: E2 protein] N - [sulfur carrier] long-chain fatty tRNA bifunctional carbonate peptide- α-D-glucosamine dTDP- F6P elongator tRNA ] glycerol-3- 3-oxoacyl-ACP 3-oxoacyl-ACP ribonucleoside- >6)-lipid IVlauroyl phosphomannomutase/ Met PD_RS04090 octanoyl-L-lysine acid--CoA ligase: guanosine(34) ADP-dependent dehydratase: methionine 3-oxoacyl-ACP A glucose 4,6- glutamine--fructose- tRNA lipoyl synthase: phosphate 1-O- synthase III: nucleoside triphosphate reductase FabG: diphosphate acyltransferase: phosphoglucomutase: 2-oxoglutarate PD_RS01230 transglycosylase PD_RS04075 (S)-S-oxide reductase acyl-[acyl-carrier- dehydratase: 6-phosphate mannose-1-phosphate PD_RS02765 a [pyruvate acyltransferase: PD_RS05510 pyrophosphohydrolase: PD_RS00755 reductase: NAD(P)H-hydrate PD_RS03080 guanylyltransferase/ α PD_RS00640 GTP ppGpp Tgt: PD_RS00950 PD_RS00810 PD_RS02510 dehydratase/ carbonate reductase: FabG: protein]--UDP-N- PD_RS01105 aminotransferase: -D-glucopyranose N-end rule pathway I (prokaryotic) L-asparagine an unsulfurated dehydrogenase PD_RS016751-cis-vaccenoyl- AMP diphosphate linoleoyl-CoA [+ 2a isozymes](5Z)-3-oxo- 3-oxoacyl-ACP lauroyl mannose-6- 5'-deoxyadenosine met 6 34 NAD(P)H-hydrate PD_RS04475 PD_RS00755 acetylglucosamine PD_RS00590 1-phosphate degradation I [sulfur carrier] E2 protein] N acyl-carrier protein sn-glycerol- acyl-carrier protein tetradec-5- a queuosine reductase a 2'- PD_RS02515 dehydratase: a protein-L- D-ribulose 5-phosphate acyltransferase: dTDP-4-dehydro- phosphate isomerase: lysine-- leucyl/ guanine epimerase: O-acyltransferase: Lys -lipoyl-L-lysine in tRNA dGMP FabG: fabG PD_RS09560 3-oxoacyl- α 6-deoxy-α-D- D-glucosamine UTP--glucose- a tRNA L-glutamate 3-phosphate enoyl-[acp] deoxyribonucleoside methionine- PD_RS01715 -Kdo-(2->4)-PD_RS00430 PD_RS01125 tRNA ligase: phenylalanyl- a cis,cis-delta9,21- PD_RS10060 CO H O ACP glucopyranose 6-phosphate 1-phosphate asn 5'-diphosphate 2 2 (S)-S-oxide D-arabinose α-Kdo-(2->6)- nucleoside- PD_RS02115 tRNA--protein degradation X Aromatic Compound 3-oxo-C40:2-[acp] reductase D-mannopyranose uridylyltransferase: an L-lysyl- NADPH 5-phosphate (lauroyl)-lipid IV dTDP-4- phosphoglucosamine diphosphate bifunctional (p)ppGpp Lys asparaginase: Degradation UDP-3-O-[(3R)-3- A 6-phosphate [tRNA ] transferase: FabG: fabG isomerase: myristoyl-acyl dehydrorhamnose mutase: PD_RS03580 PD_RS07660 kinase: GDP synthetase/guanosine- PD_RS03475 a [protein] PD_RS02045 a (3R)-3- hydroxymyristoyl]-N- phosphomannomutase/ lys an N-terminal glu deethylsimazine PD_RS03345 α carrier protein- 3,5-epimerase: α-D-glucosamine α PD_RS08545 pyrophosphokinase: 3',5'-bis(diphosphate) 3'- N-terminal L- asp glutamate acetyl- -D-glucosamine phosphoglucomutase: UDP- -D-glucose arginyl-[protein] undecaprenyl-diphospho-N 955/2504/ an insertion hydroxybutanoyl- aldehydo-D-arabinose dependent PD_RS01115 PD_RS08965 pyrophosphohydrolase: relA leucyl-L-arginine Glycolysis degradation uridine an L-arginyl- a cis,cis-delta9,27-3- a [protein]- UDP-3-O-[3- 1-phosphate PD_RS00640 dehydrogenase: -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine [DNA] octanoate an oleoyl-[acp] a malonyl-[acp] a protein FAD (S)-NADHX NMN sequence [acp] 5-phosphate acyltransferase: dTDP-4-dehydro- 2580 in 23S rRNA [tRNA Arg ] hydroxyC46:2-[acp] L-threonine hydroxymyristoyl] N- bifunctional N- bifunctional (p)ppGpp PD_RS04090 D-glutamyl-L-lysyl- D-alanine exodeoxyribonuclease long-chain fatty 23S rRNA FAD:protein bifunctional 5'-nucleotidase: element IS30 (3R)-3- PD_RS00430 β-L-rhamnose phosphomannomutase/ glycolysis III (from glucose) 2-oxoglutarate deethylsimazine undecaprenyldiphospho- 3-oxoacyl-ACP arginyl-tRNA- 3-oxoacyl-ACP acetylglucosamine acetylglucosamine- PRPP biosynthesis synthetase/guanosine- leucyl/ N-ethylammeline III: PD_RS04500 acid--CoA ligase: pseudouridine(955/ FMN ADP-dependent PD_RS04100 hydroxybutanoyl- α-D-Kdo-(2->4) dTDP-4- phosphoglucomutase: his histidine-- muramoylpentapeptide beta-N- synthase III: protein reductase FabG: transposase: deacetylase: 1-phosphate 3',5'-bis(diphosphate) 3'- phenylalanyl- chlorohydrolase: PD_RS01230 2504/2580) transferase: NAD(P)H-hydrate 5'-nucleotidase [acyl-carrier -α-D-Kdo- dehydrorhamnose PD_RS01130 tRNA ligase: acetylglucosaminyltransferase: exodeoxyribonuclease PD_RS05510 transferase: PD_RS00755 PD_RS11815 PD_RS09860 uridyltransferase/ D-ribose 5- pyrophosphohydrolase: tRNA--protein D-glucopyranose PD_RS07850 synthase: PD_RS08180 dehydratase/ SurE: protein] D-arabinofuranose (2->6)-lipid A reductase: α-D-mannose GDP-D-rhamnose PD_RS06725 an L-histidyl- ditrans,octacis-undecaprenyldiphospho-PD_RS09890 III: PD_RS00690 [+ 2 anisozymes] (11Z)-3- PD_RS01645 3-oxoacyl-ACP an insertion UDP-3-O-(3- phosphate PD_RS08965 transferase: N-ethylammeline a 2'- diphosphate AMP octanoyl-CoA PD_RS10485 an N-terminal PD_RS09630 dehydratase: 5-phosphate glucosamine- 1-phosphate biosynthesis ribose-phosphate [tRNA His ] a [protein] Arg reductase a [protein]-FMN- NAD(P)H-hydrate sequence IS30 hydroxymyristoyl) PD_RS01120 PD_RS03475 glucokinase: Carbohydrate Degradation UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- deoxyribonucleoside [DNA] acyl-carrier protein oxo-icos-11- a pseudouridine 955/ a tRNA 1-(β-D PD_RS08255 1-phosphate GDP a tRNA His an N-terminal arginyl-[protein] AMP epimerase: 2-dehydro-3- -α-D-glucosamine dTDP-β-L- mannose-1-phosphate GDP-α-D- diphosphokinase: N-terminal L- PD_RS01820 L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine 5'-monophosphate enoyl-[acp] FabG: fabG L-threonine ribofuranosyl) with integrated acetyltransferase: L-lysyl-[protein] 2504/2580 in 23S rRNA a cis,cis-delta9,27- PD_RS10060 a (2E)-but- deoxyphosphooctonate UDP-3-O-(3- rhamnose guanylyltransferase: mannose PD_RS10660 leucyl-L-lysine nicotinamide transposon PD_RS02230 GDP- D-glucopyranose Entner-Doudoroff pathway I 3-oxo-C46:2-[acp] 2-enoyl-[acp] aldolase: PD_RS02825 hydroxymyristoyl) phosphatidylethanolamine PD_RS01125 PRPP NADH N-acetyl-α-D- mannose 4,6- 6-phosphate glucosamine N- biosynthesis I GDP-α-D- glucosamine dehydratase: glucose-6- D-glucopyranose N-ethylammelide KDO-8P acyltransferase: mannose glycine-- 1-phosphate PD_RS08120 phosphate 6-phosphate PD_RS05345 a CDP-diacylglycerol GDP-4-dehydro- gly tRNA ligase: adenine 2503 a DNA containing a [DNA]-3'- a 5'-phospho- a peptide with 2-bromo-3-(4- Respiration isomerase: a [protein]- NAD + an L-arginyl- an N-terminal L- a cis,cis-delta7,19-3- a ribonucleoside an ADP-sugar DHAP roseoflavin CDP-diacylglycerol--serine bifunctional N- α-D-rhamnose PD_RS04375 in 23S rRNA S methyl an N-terminal glutathione nitrophenyl) UDP-3-O-(3- p L-cysteine hydroxyl [DNA] [tRNA Arg ] aspartyl-[protein] hydroxyC38:2-[acp] 5'-monophosphate a butanoyl-[acp] O-phosphatidyltransferase: acetylglucosamine- PD_RS04380 PD_RS01000 23S rRNA phosphotriester methylated-DNA-- DNA ligase Xaa-L-prolineXaa-Pro propanoateglutathione S- 3-oxoacyl-ACP ADP glycerol-3- bifunctional hydroxymyristoyl) GDP-6-deoxy- Gly arginyl-tRNA- 5'-nucleotidase: PD_RS08605 1-phosphate a glycyl-[tRNA ] 2-oxoglutarate decarboxylation to succinyl-CoA 6-phospho (adenine(2503)-C(2) (NAD(+)) LigA: compounds phosphate riboflavin α glucosamine N- D-lyxo-4- Secondary Metabolite Biosynthesis F6P [protein]-cysteine S- aminopeptidase: protein transferase: reductase FabG: PD_RS04100 beta-ketoacyl- -Kdo a 3-sn-phosphatidyl-L-serine uridyltransferase/ a tRNA Gly D-glucono- )-methyltransferase PD_RS10275 hydrolase dehydrogenase kinase/FAD acyltransferase: hexulose a [2-oxoglutarate methyltransferase: PD_RS04185 transferase: 2-(glutathion-PD_RS02560 PD_RS00755 5'-nucleotidase [acyl-carrier- glucosamine- 1,5-lactone RlmN: PD_RS08540 NudE: (NAD(P)(+)): synthetase: 3-deoxy-manno- PD_RS01725 phosphatidylserine reductase: methylerythritol phosphate pathway I dehydrogenase 6-phosphofructokinase: PD_RS10450a DNA without a peptide with [+ 2 isozymes] an N-terminal PD_RS01645 S-yl)-3-(4- 3-oxoacyl-ACP SurE: a 2-methyladenine 2503 a [protein]-S- NMN AMP [DNA] bromide PD_RS00820 PD_RS05590 PD_RS07600 protein] 1-phosphate preQ biosynthesis 6 PD_RS01170 6-phosphogluconolactonase: a proteinogenic Arg octulosonate UDP-2-N,3-O-bis[(3R)- decarboxylase PD_RS08115 0 E2 protein] N 5'-deoxyadenosine met S methyl an N-terminal L-arginiyl-L- a tRNA nitrophenyl) reductase PD_RS09630 2-oxoglutarate in 23S rRNA methyl-L-cysteine p sn-glycerol roseoflavin synthase II: cytidylyltransferase: acetyltransferase: α β PD_RS01815 phosphotriester amino acid propanoate FabG: fabG an α-D-aldose 3-hydroxytetradecanoyl]- proenzyme: PD_RS03140 GDP- -D- pyruvate D-glyceraldehyde 3-phosphate -lipoyl-L-lysine dehydrogenase -D-fructose 1,6- L-proline aspartyl-[protein] a ribonucleoside 5'-phosphate PD_RS07905 PD_RS07070 α PD_RS02230 methionine-- a cis,cis-delta7,19- 1-phosphate AMP 3-phosphate -D-glucosamine rhamnose met 2-oxoglutarate E1 component: bisphosphate D-gluconate [+ 2 isozymes] UDP-2,3- an L-1-phosphatidylethanolamine UDP-N-acetyl- 1-deoxy-D-xylulose-5- GTP tRNA ligase: dehydrogenase 6-phosphate 3-oxo-C38:2-[acp] CMP-Kdo α-D-glucosamine PD_RS03960 a 3-oxohexanoyl- diacylglucosamine phosphate synthase: GTP cyclohydrolase PD_RS08355 an L-methionyl- E1 component: fructose- phosphogluconate [acp] hydrolase: Nucleoside and Nucleotide Biosynthesis PD_RS06845 I FolE2: PD_RS04070 [initiator tRNA Met ] PD_RS03960 bisphosphate dehydratase: Met an E. coli a Chi-site containing an N-terminal 966 a protein-L- PD_RS10405 GTP cyclohydrolase initiator tRNA [+ 2 isozymes] aldolase class PD_RS01810 a 2'-deoxyribonucleoside sn-glycerol an L-arginyl- a guanine a cis,cis-delta7,25-3- (2R,3S)-2- 3-oxoacyl-ACP a [2-oxoglutarate a [2-oxoglutarate osmoregulated an L-1- double stranded RecA [DNA] a myristoyl-[acp] 3-sulfino-L- a myristoyl-[acp] Ap4A methionine- 1-deoxy-D-xylulose 5-phosphate 5'-triphosphate Arg in 16S rRNA methylisocitrate superpathway of pyrimidine I FolE: PD_RS04285 dehydrogenase dehydrogenase I: PD_RS09780 3-phosphate [tRNA ] hydroxyC44:2-[acp] (R)-S-oxide reductase lipid X long-chain fatty superpathway of guanosine inosine-5'-phosphate biosynthesis I 7,8-dihydroneopterin 3'-triphosphate periplasmic phosphatidylethanolamine DNA with a blunt end exodeoxyribonuclease DNA polymerase glycerol-3- alanyl-[protein]arginyl-tRNA- 16S rRNA 3-oxoacyl-ACP 3-oxoacyl-ACP bifunctional bis(5'-nucleosyl)- peptide- deoxyribonucleotides de novo biosynthesis E2 protein] N 6 E2 protein] N 6 -S- KDGP phosphoethanolamine FabG: acid activation nucleotides de novo biosynthesis I 1-deoxy-D-xylulose- glucan (OPG) V: PD_RS08680 III subunit gamma/ phosphate 1-O- protein (guanine(966)-N(2) reductase FabG: synthase III: aconitate tetraphosphatase lipid-A- -dihydrolipoyl- succinyldihydrolipoyl- transferase: methionine PD_RS00755 5-phosphate 6-carboxytetrahydropterin triose- an E. coli osmoregulated PD_RS08690 tau: PD_RS05565 acyltransferase: transferase: )-methyltransferase PD_RS00755 PD_RS05510 hydratase 2/2- (symmetrical): (R)-S-oxide disaccharide a long-chain gln hydrogencarbonate AIR L-lysine L-lysine PD_RS08880 RsmD: PD_RS01470 3-oxoacyl- reductoisomerase: synthase QueD: phosphate 2-keto-3- PD_RS08695 PD_RS01675 PD_RS01645 an N 2 - [+ 2 isozymes] methylisocitrate PD_RS06380 synthase: fatty acid a 1,2-diacyl- periplasmic glucan with a double stranded DNA [+ 8 isozymes] 1-myristoyl- an N-terminal L- 3-oxoacyl-ACP reductase: long-chain IMP PD_RS01740 PD_RS00840 966 a 3-oxohexadecanoyl- dehydratase: ACP 5-(carboxyamino) isomerase: deoxygluconate sn-glycerol phosphotidylethanolamine with a RecA protein [DNA] acyl-carrier protein sn-glycerol arginiyl-3-sulfino- a tRNA Arg methylguanine reductase PD_RS09675 PD_RS01710 fatty acid-- PD_RS01320 [acp] PD_RS01250 ADP a [protein]-L- reductase carbamoyl- imidazole ribonucleotide 6-carboxy-5,6,7,8-tetrahydropterin D-glyceraldehyde 6-phosphate substituent loaded 3' overhang 3-phosphate L-alanyl-[protein] in 16S rRNA FabG: fabG CoA ligase: Amine and Polyamine Biosynthesis IMP MEP dihydrolipoyllysine- DHAP a cis,cis-delta7,25- cis-2- methionine FabG: fabG lipid A disaccharide (E. coli) phosphate synthase: PD_RS10740 3-phosphate aldolase: a (3R)-3- PD_RS01230 dehydrogenase: residue 3-oxo-C44:2-[acp] methylaconitate a long-chain synthase: 7-carboxy-7- glyceraldehyde- PD_RS01805 hydroxyhexanoyl- tetraacyldisaccharide spermidine biosynthesis III PD_RS07650 N5-CAIR 2-C-methyl-D- deazaguanine synthase succinyltransferase: fatty acyl-CoA spermidine biosynthesis I PD_RS02085 asp 3-phosphate [acp] 4'-kinase: PD_RS01905 erythritol 4-phosphate QueE: PD_RS04680 PD_RS03955 D-glyceraldehyde carB 5-(carboxyamino) dehydrogenase: pyruvate (3R)-3- XMP cytidylyltransferase: 3-phosphate decaprenyl-diphospho-N- UDP-N-acetyl- a double an N-terminal adenine 2030 an adenosine 34 lipid IV imidazole ribonucleotide 2-oxoglutarate PD_RS08550 sn-glycerol an L-arginyl- a cis,cis-delta5,17-3- A arg SAM PD_RS02840 7-carboxy-7-deazaguanine acetylmuramoyl-pentapeptide α-D-glucosamine a palmitoyl-[acp] 3-sulfo-L- a lignoceroyl-[acp] roseoflavin Arg2 3',5'-ADP hydroxyhexanoyl- dehydrogenase stranded DNA Arg in 23S rRNA in [tRNA ] SAM mutase: PD_RS10745 glyceraldehyde- undecaprenyldiphospho- hypoxanthine PRPP 3-phosphate [tRNA ] hydroxyC36:2[acp] ATP [acyl-carrier carbamoyl 4-(cytidine 5'-diphospho) E1 component: exodeoxyribonuclease glycerol-3- alanyl-[protein]arginyl-tRNA- 23S rRNA 3-oxoacyl-ACP 3-oxoacyl-ACP 5'-phosphate tRNA 3'(2'),5'- S-adenosylmethionine GMP synthase: 13-DPG 3-phosphate muramoylpentapeptide beta-N- hypoxanthine-guanine protein] 3-deoxy-D-manno- arginine S-adenosylmethionine phosphate asp CAIR -2-C-methyl-D-erythritol 7-cyano-7-deazaguanine PD_RS03960 V: PD_RS08680 phosphate 1-O- protein (adenine(2030)-N(6) reductase FabG: synthase III: bifunctional adenosine(34) bisphosphate decarboxylase PD_RS08310 dehydrogenase: acetylglucosaminyltransferase: phosphoribosyltransferase: dehydratase: octulosonic acid decarboxylase, decarboxylase 4-diphosphocytidyl- synthase: PD_RS04890 PD_RS08690 acyltransferase: transferase: )-methyltransferase PD_RS00755 PD_RS05510 riboflavin deaminase nucleotidase: proenzyme: PD_RS03910 phosphoglycerate PD_RS08550 PD_RS09890 PD_RS07300 PD_RS08255 transferase: biosynthetic: proenzyme: aspartate 2C-methyl-D-erythritol PD_RS08695 PD_RS01675 PD_RS01645 6 RlmJ: PD_RS00175 [+ 2 isozymes] kinase/FAD TadA: PD_RS00815 putrescine dAdoMet phosphoribosylaminoimidazolesuccinocarboxamide preQ kinase: PD_RS09790 decaprenyl-pyrophosphoryl- IMP 1-palmitoyl- an N-terminal L- an N - 3-oxoacyl-ACP PD_RS00435 PD_RS00605 PD_RS03910 carbamoyltransferase GMP kinase: PD_RS10670 0 a 5'-phosphooligonucleotide Arg 2030 a 3-oxohexacosanoyl- synthetase: PD_RS01630 a (2E)-hex- phosphatidylglycerol 13-DPG UDP (N-acetylglucosamine)-N- acyl-carrier protein sn-glycerol arginiyl-3-sulfo- a tRNA methyladenine reductase 34 spermidine synthase: catalytic subunit: synthase: PD_RS00880 2-phospho-4-(cytidine 5'- 3-phospho- [acp] PD_RS07600 an inosine AMP acetylmuramyl-(pentapeptide) 3-phosphate L-alanyl-[protein] in 23S rRNA FabG: fabG roseoflavin adenine Arg2 2-enoyl-[acp] biosynthesis I (plastidic) agmatine dAdoMet D-glycerate in [tRNA ] α-Kdo-(2->6)-lipid IV PD_RS00600 PD_RS06745 guanylate diphospho)-2-C-methyl-D-erythritol phosphoglycerate a cis,cis-delta5,17- dinucleotide A kinase: SAICAR 3-oxo-C36:2-[acp] DHAP spermidine 2-C-methyl-D-erythritol phosphoglycerate kinase: PD_RS09790 KDO transferase: polyamine PD_RS03745 2,4-cyclodiphosphate mutase: gpmA glycerol-3- N-carbamoyl- 3-phospho- PD_RS00435 aminopropyltransferase: L-aspartate adenylosuccinate synthase: PD_RS02845 myo-inositol phosphate 2-phospho- D-glycerate 6 a hexanoyl-[acp] α-Kdo-(2->4)-α- PD_RS00600 GDP lyase: PD_RS03970 biosynthesis an N -L- 3-benzyl-3,6- a DNA containing sn-glycerol an organic (3R,5S)-3- dehydrogenase 2-C-methyl-D-erythritol- D-glycerate 37 a 2,3,4-saturated fatty acid guanosine 2251 in 23S rRNA sn-glycerol a cis,cis-delta5,23-3- Kdo-(2->6)-lipid IV dihydroorotase: phosphoglycerate chitin degradation II (Vibrio) threonylcarbamoyladenine a stearoyl-[acp] dihydroxy-6- an apurinic/ a dodecanoyl-[acp] 3-phosphate hydroperoxide hydroxy-1- A (NAD(P)(+)): 2,4-cyclodiphosphate D-glucopyranose 3-phosphate glutathione hydroxyC42:2-[acp] S-methyl-5'- N 1 -(3-aminopropyl) PD_RS01505 AICAR enolase: mutase: gpmA in tRNA long-chain fatty 23S rRNA (hydroxymethyl) apyrimidinic site 3-oxoacyl-ACP 3-oxoacyl-ACP glycerol-3- alkyl pyrroline-5- beta-ketoacyl- PD_RS05590 6-phosphate tRNA glycerol-3- glutathione S- lauroyl thioadenosine agmatine flavodoxin-dependent PD_RS02830 acid--CoA ligase: (guanosine(2251)-2'- -diketopiperazine deoxyribonuclease reductase FabG: synthase III: phosphate 1-O- hydroperoxide carboxylatepyrroline-5- [acyl-carrier- sn-glycerol nucleoside- ribonucleoside- bifunctional 2-phospho- chitin threonylcarbamoyladenosine phosphate 1-O- transferase: Peptide RS04695 Peptide acyltransferase: (S)-dihydroorotate (E)-4-hydroxy-3- PD_RS01230 O)-methyltransferase V: PD_RS04690 PD_RS00755 PD_RS05510 acyltransferase: reductase carboxylate a sugar RS10325 a sugar protein] 3-phosphate diphosphate diphosphate phosphoribosylaminoimidazolecarboxamide phosphoenol D-glycerate dehydratase: PD_RS03935 acyltransferase: 3-benzyl-3,6PD_RS02560 - synthase II: PD_RS03080 methylbut-2-enyl- pyruvate chitinase: a cyclic N 6 -L- a 2,3,4-saturated RlmB: PD_RS04275 PD_RS01675 bis(glutathione)- a 2'- 3-oxoacyl-ACP [+ 2 isozymes] PD_RS01675 subunit F: reductase: Kdo -(palmitoleoyl)-lipid IV glycerol-3- dihydroorotate kinase: reductase: formyltransferase/inosine monophosphate Ins(3)P AMP diphosphate 2-O-methylguanosine 2251 1-stearoyl- 1-(18- 2 A diphosphate synthase: enolase: PD_RS03390 threonylcarbamoyladenosine deoxyribonucleoside a 3-oxotetradecanoyl- PD_RS03870 PD_RS10890 PD_RS07905 lauroyl phosphate 1-O- PD_RS08545 PD_RS02510 cyclohydrolase: PD_RS04315 pyruvate fatty acyl CoA in 23S rRNA acyl-carrier protein sn-glycerol 6-(hydroxymethyl) reductase hydroxyoleoyl) dehydrogenase PD_RS10355 PD_RS02830 [acp] Hyp [+ 2 isozymes] acyltransferase: acyltransferase: spermidine PD_RS02515 inositol kinase: 37 in tRNA 3-phosphate -diketopiperazine 5'-monophosphate FabG: fabG -sn-glycrol an alcohol lipid A RS01900 lipid A (quinone): a chitodextrin a cis,cis-delta5,23- a sugar RS07730 a sugar PD_RS00430 PD_RS01675 FAICAR (E)-4-hydroxy-3-methylbut- monophosphatase: PD_RS09785 phosphoenol 3-phosphate a 3-oxooctanoyl- PD_RS10335 3-oxo-C42:2-[acp] a 1-acyl-sn GTP 2-en-1-yl diphosphate PD_RS07870 superpathway of glycolysis and the Entner-Doudoroff pathway pyruvate [acp] α-Kdo-(2->4)-α-Kdo- (Kdo) -lipid A, cold adapted bifunctional pyruvate 2 -glycerol 3- orotate PRPP dGDP pyruvate (2->6)-(lauroyl)-lipid IV phosphoribosylaminoimidazolecarboxamide myo-inositol 2+ 2+ 3-oxoacyl-ACP A phosphate D-glucopyranose kinase: Mg Mg an anion RS10030 an anion dimethylallyl- isopentenyl- an odd numbered RS06375 reductase myristoyl-acyl formyltransferase/inosine monophosphate a chitodextrin adenine 1518 / 2+ 2+ orotate nucleoside- diphosphate:NAD(P) diphosphate:NAD(P) 6-phosphate PD_RS09785 α-linolenate O-succinyl-L- an L-arginyl- an N-terminal L- chitin NaMN Co Co cyclohydrolase: PD_RS04315 straight chain 2,3,4- methanethiol 1519 a behenoyl-[acp] a butanoyl-[acp] a protein FabG: carrier protein- phosphoribosyltransferase: homoserine [tRNA Arg ] glutamyl-[protein] adenine in 16S rRNA GTP H O RS00545 diphosphate + oxidoreductase: + oxidoreductase: saturated fatty acid long-chain fatty ribosomal RNA 2 beta- 5'-nucleotidase: PD_RS00755 dependent PD_RS00650 pyruvate long-chain fatty O-succinylhomoserine arginyl-tRNA- 3-oxoacyl-ACP 3-oxoacyl-ACP a 1,2-diacyl- kinase: PD_RS07585 PD_RS07585 acid--CoA ligase: small subunit GTPase Era: hexosaminidase: PD_RS04100 S41 family 3-oxoacyl- acyltransferase: IMP acid--CoA ligase: (thiol)-lyase: protein synthase III: synthase III: Co 2+ Co 2+ ammonia RS05390 ammonia sn-glycerol orotidine 5'- PD_RS08545 PD_RS01230 methyltransferase PD_RS06835 PD_RS07305 peptidase: RS09420 ACP PD_RS00430 PD_RS01230 PD_RS09610 transferase: PD_RS05510 5'-nucleotidase PD_RS05510 Mg 2+ Mg 2+ 3-phosphate phosphate an odd numbered A: PD_RS06370 [+ 3 isozymes] beta- PD_RS10855 reductase α-D-Kdo-(2->4)-α- Aromatic Compound Biosynthesis guanine and DMAPP IPP beta- succinate met an N-terminal PD_RS01645 N 6 -dimethyladenine 1518 [+ 2 isozymes] SurE: [+ 2 isozymes] phosphatidate dGTP diphosphate AMP straight chain 2,3,4- AMP diphosphate α-linolenoyl-CoA phosphate GDP H + hexosaminidase: hexosaminidase: Arg /N 6 -dimethyladenine 1519 a 3-oxotetracosanoyl- PD_RS09630 a 3-oxohexanoyl- a peptide FabG: fabG D-Kdo-(2->6)-lipid A cytidylyltransferase: orotidine-5'- guanosine salvage II glucose-6- saturated fatty acyl CoA L-arginiyl-L- a tRNA PD_RS09685 β-D- PD_RS09685 in 16S rRNA [acp] [acp] a metal a metal L-fucose RS06150 L-fucose a (3R)-3- PD_RS01745 chorismate biosynthesis I 4-hydroxyphenylpyruvate phosphate phosphate glutamyl-[protein] N-acetyl-D- ribosylnicotinate RS09605 6-phospho chitin cation cation hydroxyoctanoyl- a CDP- biosynthesis decarboxylase: isomerase: beta- glucosamine D-erythrose guanosine D-glucono- [acp] diacylglycerol PD_RS00140 superpathway of 5-aminoimidazole PD_RS01000 hexosaminidase: (3R)-3- 4-phosphate 1,5-lactone ribonucleotide biosynthesis N,N'- PD_RS07305 N,N',N''- 6 CDP-diacylglycerol-- 3-deoxy-7- UMP an O - 2498 a 5,6- hydroxyoctanoyl- tyr 6-phosphogluconolactonase: UDP-N-acetyl-α-D-muramoyl- a cytidine a negatively pyridoxamine a metal a metal nitrate RS08740 nitrate palmitoleate biosynthesis I phosphoheptulonate diacetylchitobiose triacetylchitotriose a [protein]- O-succinyl-L- 3-phenyl-2- 20 RS01640 glycerol-3-phosphate 3- aspartate/ superpathway of meso-diaminopimelate methylguanine tyr in 23S rRNA dihydrouracil a protein supercoiled DNA a decanoyl-[acp] cation cation [acyl-carrier (from (5Z)-dodec-5-enoate) synthase: PD_RS00095 cytidylate PRPP PD_RS01815 beta- L-alanyl-D-glutamate L-cysteine homoserine oxopropanoate dATP 5'-phosphate phosphatidyltransferase: 3-deoxy-D-arabino- tyrosine/aromatic adenosine nucleotides guanine in DNA O-succinylhomoserine 23S rRNA in tRNA metalloprotease DNA 3-oxoacyl-ACP pyridoxamine protein] kinase: amidophosphoribosyltransferase: D-gluconate hexosaminidase: UDP-N-acetylmuramoyl- methylated-DNA-- aspartate/ tRNA PD_RS07015 heptulosonate aminotransferase: de novo biosynthesis I (thiol)-lyase: (cytidine(2498)-2'-O) nucleoside triphosphate TldD: PD_RS02185 topoisomerase synthase III: 5'-phosphate dehydratase: a (5Z)-dodec- PD_RS07695 PD_RS04430 6-phosphate PD_RS07305 L-alanyl-D-glutamate-- [protein]-cysteine S- tyrosine/aromatic dihydrouridine(20/ 1-(3-sn- 7-phosphate 3-(4- PD_RS00145 hypoxanthine-guanine PD_RS09610 -methyltransferase pyrophosphohydrolase: IV subunit B: PD_RS05510 oxidase: a metal a metal PD_RS08255 5-enoyl-[acp]3-oxoacyl-ACP UMP kinase: amidophosphoribosyltransferase: 2, 6-diaminopimelate methyltransferase: aminotransferase: 20a) synthase metalloprotease RS03265 phosphatidyl) 3-dehydroquinate hydroxyphenyl) IMP asp phosphoribosyltransferase: phosphogluconate beta- RlmM: PD_RS10090 PD_RS00810 PD_RS02810 PD_RS03035 cation cation a (2E)-oct- synthase III: PD_RS01780 PD_RS00240 F6P ligase: PD_RS09910 PD_RS10450 succinate L-homocysteine 3-(4-PD_RS00145 a 2-O- DusA: PD_RS08840 PmbA: PD_RS02195 a 3- [+ 2 isozymes] -sn-glycerol synthase: pyruvate β PD_RS07300 dehydratase: hexosaminidase: UDP-N-acetyl-α-D-muramoyl-L-alanyl- a [protein]-S- 2498 5-phospho- - methylcytidine 20 [+ 3 isozymes] PLP 2-enoyl-[acp] PD_RS05510 3-phosphate adenylosuccinate γ a guanine in DNA phe hydroxyphenyl) a uracil in tRNA a peptide oxododecanoyl- PD_RS03025 UDP D-ribosylamine PD_RS01810 6-phosphofructokinase: PD_RS09685 -D-glutamyl-meso-2,6-diaminopimelate methyl-L-cysteine in 23S rRNA dAMP a relaxed DNA a (7Z)-3- synthetase: pyruvate [acp] [+ 2 isozymes] phosphoribosylamine- GMP PD_RS01170 N-acetyl-D- oxotetradec- 3-dehydroquinate ribonucleoside- nucleoside- PD_RS08555 KDGP adenylo-succinate -glycine ligase: β glucosamine 7-enoyl-[acp] -D-fructose 1,6- an L-1- 3-dehydroquinate diphosphate diphosphate DHAP PD_RS04310 bisphosphate 4 3-oxoacyl- reductase: kinase: adenylosuccinate core an O - an [L-cysteine 1402 a peptidyl- 2605 phosphatidyl- dehydratase: a [protein]- a cytosine 32 a cytidine long chain uridine a nucleoside an octanoyl-[acp] ACP 2-keto-3- fructose- a 5-L-glutamyl- desulfurase]-S- a hexanoyl-[acp] sn-glycerol PD_RS00195 PD_RS02510 PD_RS08545 lyase: PD_RS03970 GAR an L-1- oligosaccharide- methylthymine an amino acid in 16S rRNA GTP dipeptidase in 23S rRNA reductase deoxygluconate bisphosphate triose- L-cysteine [peptide] sulfanyl-L-cysteine in tRNA polyphosphate diphosphate PD_RS02515 chitin degradation III (Serratia) phosphatidylethanolamine lipid A (E. coli in DNA methylated-DNA-- gamma- tRNA 2- 16S rRNA Dcp substratepeptidyl- ribosomal 3-oxoacyl-ACP nucleoside- beta-ketoacyl- FabG: fabG phosphoribosylglycinamide 6-phosphate aldolase class phosphate 3-dehydroshikimate CMP phosphoethanolamineK-12 core type) [protein]-cysteine S- glutamyltransferase: thiocytidine(32) (cytosine(1402)-N(4) exopolyphosphatase: nucleoside triphosphate dipeptidase large subunit synthase III: diphosphate [acyl-carrier- gln UTP AMP formyltransferase: aldolase: I: PD_RS09780 isomerase: transferase: )-methyltransferase pseudouridine 3-oxoacyl-ACP dUDP phosphorylation chitin methyltransferase: an αPD_RS01490-(5-L- synthetase TtcA: PD_RS10410 pyrophosphohydrolase: Dcp: PD_RS05510 kinase: protein] PD_RS08225 PD_RS01805 PD_RS01320 lipid A-core- PD_RS08880 RsmH: PD_RS09925 synthase B: reductase a 1,2-diacyl- PD_RS10450 a peptide glutamyl)- PD_RS08260an [L-cysteine an N 4 - PD_RS00810 PD_RS04455 [+ 2 isozymes] PD_RS08545 synthase II: acyl-CoA hydrolysis nucleoside- CMP phosphoethanolamine a 2-thiocytosine 32 long chain a nucleoside FabG: a [protein]-S- 1402 PD_RS07760 a 3-oxooctanoyl- CTP adenylate kinase: FGAR sn-glycerol a thymine in DNA amino acid desulfurase]- methylcytidine a dipeptide a peptide 2605 PD_RS07905 biotin-carboxyl carrier diphosphate cytidylate D-glyceraldehyde (hep I) methyl-L-cysteine in tRNA polyphosphate GMP a pseudouridine [acp] triphosphate PD_RS00755 a 2,3,4-saturated synthetase: PD_RS01175 L-cysteine in 16S rRNA [+ 2 isozymes] a (3R,7Z)-3- protein assembly shikimate kinase: kinase: 3-phosphate in 23S rRNA fatty acyl CoA PD_RS08545 pyrG phosphoribosylformylglycinamidine PD_RS07695 [(1->4)-β-N-acetyl-D-glucosaminyl] a 3-oxodecanoyl- hydroxytetradec- a [biotin carboxyl- acyl-CoA glyceraldehyde- chitin n shikimate ADP synthase: PD_RS03385 CDP -(1->4)-2-(acetylamino)-2- [acp] 7-enoyl-[acp] carrier protein]-L-lysine thioesterase II: dUTP CTP 3-phosphate kinase: aroK deoxy-D-glucono-1,5-lactone a [pyruvate dehydrogenase PD_RS01655 FGAM nucleoside- dehydrogenase: core a 5-aminomethyl-2- sn-glycerol bifunctional a 2,3,4-saturated dUTP chitinase: isobutanoate a proteinogenic 6 a RNA-DNA hybrid 3-oxoacyl-ACP ribonucleoside- PD_RS08550 an L-1- oligosaccharide- glutathione E2 protein] N -S- 34 an arachidoyl-[acp] a malonyl-[acp] ser biotin-- fatty acid diphosphate PD_RS03390 amino acid thiouridine in tRNA ITP 3-phosphate reductase shikimate 3-phosphate diphosphatase: diphosphate phosphatidylethanolamine lipid A (E. coli acetyl-coenzyme acetyldihydrolipoyl-L-lysine ribonuclease HI: tRNA 2- glycerol-3- a (2E,7Z)- [acetyl-CoA- phosphoribosylformylglycinamidine kinase: gamma- dihydrolipoyllysine- 3-oxoacyl-ACP 3-oxoacyl-ACP threonine/ FabG: PD_RS00635 CDP reductase: 13-DPG [(1->4)-β-N-acetyl-D- phosphoethanolamineK-12 core type) A synthetase: PD_RS06420 thiouridine(34) phosphate 1-O- tetradeca-2,7- carboxylase] 3-phosphoshikimate 1- cyclo-ligase: PD_RS08215 PD_RS08545 glutamyltransferase: residue nucleoside triphosphate synthase III: synthase III: serine PD_RS00755 nucleoside triphosphate PD_RS02510 a chitodextrin glucosaminyl] -(1->4)-N-acetyl- transferase: PD_RS06860 ribonuclease HII: synthase MnmA: acyltransferase: dienoyl-[acp] ribonucleoside- n PD_RS01490an α-(γ-L- acetyltransferase: pyrophosphohydrolase: PD_RS05510 PD_RS05510 dehydratase: synthetase/ carboxyvinyltransferase: pyrophosphohydrolase: PD_RS02515 AIR CTP phosphoglycerate 2-deoxy-2-amino-D-gluconate PD_RS03450 3-oxoacyl- diphosphate lipid A-core- PD_RS08880a 1,2-diacyl- L-cysteinylglycine glutamyl)-L- a [pyruvate dehydrogenasePD_RS09595 PD_RS01705 PD_RS00810 1-C16:0-α,ωPD_RS01675- [+ 2 isozymes] a 3- [+ 2 isozymes] PD_RS05500 biotin operon PD_RS07170 PD_RS00810 isobutanoyl-CoA AMP diphosphate a nucleoside 5'- a 5-methylaminomethyl- a 3- ACP reductase: kinase: PD_RS09790 chitinase: 6 repressor: 5-enolpyruvoyl- pyrophosphoethanolamine sn-glycerol amino acid E2 protein] N - DNA 2-thiouridine 34 in tRNA dicarboxyl-2- oxodocosanoyl- oxodocosanoyl- pyruvate reductase PD_RS02510 dADP PD_RS03390 monophosphate IMP PD_RS05625 shikimate 3-phosphate dUMP 3-phospho- dihydrolipoyl-L-lysine lysophosphatidate [acp] [acp] FabG: fabG PD_RS02515 guanine and a (7Z)-tetradec- a [biotin carboxyl- thymidylate D-glycerate a (3R)-3- 7-enoyl-[acp] chorismate nucleoside- guanosine salvage N,N'-diacetylchitobiose hydroxydecanoyl- carrier protein]-N synthase: dCDP diphosphate kinase: pyrimidine deoxyribonucleotide phosphoglycerate 6 synthase: beta-ketoacyl- -biotinyl-L-lysine phosphorylation 967 2552 [acp] PD_RS03155 PD_RS07210 nucleoside- PD_RS08545 mutase: gpmA beta-hexosaminidase: L-alanyl-γ-D-glutamyl-meso- a carboxy- a cytosine an [amino group carrier uridine sn-glycerol [acyl-carrier- UDP-N-acetyl-α-D-muramate pristanate O-phospho- oleate γ histidinol 3-hydroxydecanoyl- dTMP diphosphate guanosine dTMP dCMP 2-phospho- PD_RS07305 2,6-diaminopimeloyl-D-alanine cys cys adenylated-[ThiS in 16S rRNA protein]-C-terminal- - in 23S rRNA a stearoyl-[acp] 3-phosphate protein] chorismate guanosine long-chain fatty L-homoserine sulfur-carrier protein] ribosomal RNA (L-glutamyl)-L-glutamate ribosomal RNA ACP dehydratase: kinase: dATP thymidylate cytidylate D-glycerate beta-hexosaminidase: UDP-N-acetylmuramate:L- O-succinylhomoserine long-chain fatty cysteine 3-oxoacyl-ACP glycerol-3- histidinol synthase II: thymidylate phosphorylase: acid--CoA ligase: small subunit acetylglutamate large subunit PD_RS08255 a [biotin carboxyl- PD_RS08545 kinase: kinase: PD_RS09685 alanyl-gamma-D-glutamyl- (thiol)-lyase: acid--CoA ligase: desulfurase: synthase III: phosphate 1-O- dehydrogenase: PD_RS07905 kinase: PD_RS07295 enolase: PD_RS01230 PD_RS01230 methyltransferase kinase: methyltransferase a (2E)-dec- carrier-protein dimer]- PD_RS08240 PD_RS07695 meso-diaminopimelate PD_RS09610 PD_RS03605 PD_RS05510 acyltransferase: PD_RS06710 6 PD_RS08240 dCTP PD_RS02830 PD_RS01565 [+ 2 isozymes] N -biotinyl-L-lysine guanine dTDP dCDP N-acetyl-D-glucosamine ligase: PD_RS01180 a thiocarboxy- B: PD_RS09295 an [amino group carrier a 2'-O- E: PD_RS00390 [+ 2 isozymes] 1-oleoyl-snPD_RS01675 2-enoyl-[acp] UDP-N-acetylmuramoyl-L-alanyl-γ-D- AMP diphosphate pristanoyl-CoA L-cystathionine diphosphate AMP oleoyl-CoA AMP ala a 5-methylcytosine 967 a (9Z)-3- acetyl-CoA dTDP phosphoenol 2552 a 3-oxoicosanoyl- his nucleoside- nucleoside- glutamyl-meso-2,6-diaminopimeloyl-D-alanine [ThiS-Protein] in 16S rRNA protein]-C-terminal- methyluridine -glycerol 3- oxohexadec- carboxylase hypoxanthine-guanine pyruvate γ [acp] nucleoside- diphosphate diphosphate -(5-phospho-L- in 23S rRNA phosphate 9-enoyl-[acp] carboxyltransferase phosphoribosyltransferase: pyruvate glutamyl)-L-glutamate 3-oxoacyl-ACP diphosphate kinase: kinase: phosphoenolpyruvate subunit beta: acetyl-CoA PD_RS07300 kinase: D-mannose degradation C1 Compound Utilization reductase kinase: PD_RS08545 PD_RS08545 synthase: PD_RS02735 a decanoyl-[acp] PD_RS03575 carboxylase PD_RS09785 and Assimilation PD_RS08545 38- DNA with adenine:7,8- FabG: biotin GMP dTTP dCTP D-mannopyranose a nucleoside a uridine dCDP acetyl-CoA SAM a sulfurated dethiobiotin phytenate aci-nitroethane pimeloyl-CoA ala dihydro-8- [DNA] an octanoyl-[acp] a protein PD_RS00755 carboxylase dTTP pyruvate 6-phosphate formaldehyde oxidation triphosphate 40 in tRNA ribonucleoside- beta-ketoacyl- carboxylase mannose-1-phosphate [sulfur carrier] long-chain fatty nitronate tRNA oxoguanine mismatch type I restriction 3-oxoacyl- subunit: VII (THF pathway) biotin nucleoside triphosphate 8-amino-7- A/G-specific 3-oxoacyl-ACP diphosphate [acyl-carrier- carboxyl guanylyltransferase/ acid--CoA ligase: monooxygenase: pseudouridine(38- endonuclease ACP PD_RS00205 synthase: pyrophosphohydrolase: oxononanoate adenine synthase III: endopeptidase reductase: protein] transferase mannose-6- PD_RS01230 PD_RS00495 40) synthase subunit R: synthase II: reductase formaldehyde PD_RS00245 [unspecified PD_RS00810 synthase: glycosylase: PD_RS05510 La: PD_RS02475 PD_RS02510 subunit alpha: phosphate isomerase: an unsulfurated degradation nitrite acetaldehyde TruA: PD_RS03175 PD_RS04610 PD_RS10955 [+ 2 isozymes] PD_RS07905 FabG: fabG Amino Acid Biosynthesis met 5'-deoxyadenosine biotin a nucleoside 5'- PD_RS03110 a pseudouridine 38- a double stranded PD_RS02515 a (3R,9Z)-3- PD_RS00870 PD_RS01125 [sulfur carrier] diphosphate AMP phytenoyl-CoA 8-amino-7- a 3-oxodecanoyl- products] monophosphate coenzyme A 40 in tRNA an apurinic site DNA with 5'- a peptide CDP [+ 2 isozymes] hydroxyhexadec- a [carboxyl-carrier F6P a 5,10- oxononanoate adenine [acp] a 3- 6 within DNA terminal phosphate 9-enoyl-[acp] protein dimer]-N - fatty acid superpathway of L- methylenetetrahydrofolate oxododecanoyl- L-histidine biosynthesis superpathway of branched chain amino acid biosynthesis L-lysine biosynthesis I L-alanine L-arginine biosynthesis I (via L-ornithine) superpathway S-adenosyl-L-methionine cycle II carboxybiotinyl-L-lysine biosynthesis initiation I isoleucine biosynthesis I L-cysteine biosynthesis bifunctional [acp] biosynthesis I of L-threonine VI (from L-methionine) 3-oxoacyl-ACP methylenetetrahydrofolate Man GlcNAc - (1S,2R)-1- a 3,5,7,9,11,13,15- acetyl-CoA oxaloacetate PRPP biosynthesis 10 9 2 a 23S rRNA 1,6-anhydro-N- UDP pyruvate thr asp 3-methyl-2- glu met dehydrogenase/ an N - an L-methionyl- isovalerate UDP-N-acetyl- uroporphyrinogen-I reductase a (2E,9Z)- Amine and Polyamine Met [protein] (isomer 1911/1915/1917 ala C-(indol-3- hepta-oxo- β repressor LexA acetyl-CoA carboxylase aspartate/ oxobutanoate oxaloacetate met S-adenosylmethionine formyltetrahydrofolate [initiator tRNA ] uridine α-D-muramate ser acetyl- -muramate ribonucleoside- FabG: hexadeca-2,9- ATP bifunctional branched-chain Degradation methenyltetrahydrofolate acetyl-coenzyme 9A B ) 23S rRNA yl)glycerol hexadecanoyl-[PKS-acp] anhydro-N- carboxyltransferase tyrosine/aromatic acetolactate N-acetylglutamate aspartate/ S-adenosylmethionine synthase: methionyl-tRNA 1,2,3 alpha-1,2-1,2,3 UDP-N- uroporphyrinogen diphosphate PD_RS00755 dienoyl-[acp] phosphoribosyltransferase: threonine/ aspartate kinase/ amino acid cyclohydrolase: PD_RS07655 A synthetase: pseudouridine(1911/ 3-phosphate tryptophan aldo/keto acetylmuramic LexA subunit beta: aminotransferase: synthase synthase: tyrosine/aromatic synthase: 5-methyltetrahydropteroyltriglutamate- PD_RS08815 formyltransferase: mannosidase: acetylmuramate-- decarboxylase: reductase: serine homoserine aminotransferase: N-acetylglucosamine a 5,10- PD_RS06860 reductase: repressor: 3-oxoacyl- PD_RS03575 PD_RS00145 PD_RS06715 2 catalytic aminotransferase: PD_RS08815 - homocysteine an N-formyl- PD_RS09300 PD_RS09710Man GlcNAc - 1915/1917) synthase PD_RS03020 synthase acid kinase: PD_RS02510 dehydrogenase PD_RS01565 degradation I β 8 2 L-alanine ligase: PD_RS08920 PD_RS00500 ACP subunit: dehydratase: PD_RS04220 methenyltetrahydrofolate -D- RluD: PD_RS09265 subunit beta: PD_RS00700 asp β PD_RS00145 SAM methyltransferase: PD_RS06915 L-methionyl- a tetrahydrofolate [protein] (isomer 1911/ PD_RS09885 9-hydroxy-3,5,7,11,13,15- N-acetyl-D- PD_RS02515 acetyl-CoA 1-(5-phospho- -D-ribosyl)-ATP PD_RS05500 I: PD_RS06740 val N-acetyl-L- N-acetyl-D- bifunctional isovaleryl-CoA AMP diphosphate mannopyranose a pseudouridine UDP-N-acetyl-α-D- coproporphyrinogen I PD_RS03185 cleaved reductase carboxylase carboxyl PD_RS05490 [initiator tRNA met ] 8A B ) D-glyceraldehyde hexaoxohexadecanoyl- muramate 6- L-aspartyl-4-phosphate glutamate asp glucosamine methylenetetrahydrofolate 1,2,3 2,3 1915/1917 in 23S rRNA muramoyl-L-alanine trp repressor LexA dUDP FabG: fabG a palmitoleoyl-[acp] bifunctional bifunctional acetolactate (2Z)-2-aminobut- 3-phosphate [PKS-acp] phosphate transferase subunit L-homocysteine SAM 6-phosphate dehydrogenase/ a (3R)-3- aspartate kinase/ phosphoribosyl- synthase: 2-enoate acetylglutamate N-acetylglucosamine- alpha: PD_RS00870 aspartate- bifunctional methenyltetrahydrofolate hydroxydodecanoyl- malonyl-CoA homoserine AMP cyclohydrolase/ PD_RS05495 kinase: 6-phosphate semialdehyde aspartate kinase/ cyclohydrolase: PD_RS07655 [acp] PD_RS01565 deacetylase: α di-trans,octa-cis Man GlcNAc - 527 5-(methylsulfanyl) dehydrogenase phosphoribosyl-ATP homoserine SAH UDP-N-acetyl- -D-muramoyl-L-alanyl- 7 2 3-[(7'-methylsulfanyl) a guanine (2R,3S)-3- D-ribulose (3R)-3- dehydrogenase: 10 D-alanyl-D-alanine α dihydrolipoamide 2-oxoadipate [acyl-carrier-protein] S I: PD_RS06740 diphosphatase: (S)-2-acetolactate ala D-glucosaminePD_RS03570 an N - γ-D-glutamyl-meso-2,6-diaminopimelate UDP- -D-glucose -undecaprenyl protein (isomer asp -2,3-dioxopentyl 5-phosphate hydroxydodecanoyl- PD_RS03165 N-acetylglutamyl- dehydrogenase heptyl]malate in 16S rRNA isopropylmalate palmitoleate -malonyltransferase: PD_RS06680 2-iminobutanoate 6-phosphate formyltetrahydrofolate UDP-N-acetylmuramoyl- phosphate 7A Balpha-1,2-) dihydrolipoyllysine- 2-oxoglutarate ribosomal RNA 3-isopropylmalate 1-phosphate ribulose- ketol-acid phosphate I: PD_RS06740 adenosylhomocysteinase: undecaprenyl- 1,2,3 1 3-isopropylmalate aspartate/ [acyl-carrier protein] PD_RS07920 L-aspartyl- L-aspartate 4- alanine formyltetrahydrofolate tripeptide--D-alanyl-D- residue dehydrogenase small subunit dehydratase: acireductone phosphate 3- reductoisomerase: PD_RS01690 phosphate glucose mannosidase: dehydrogenase: tyrosine/aromatic dehydratase: 4-phosphate 1-(5-phospho-β-D-ribosyl)-AMP semialdehyde racemase: N-acetyl- L-aspartyl- deformylase: alanine ligase: PD_RS09905 acetyltransferase: E1 component: methyltransferase PD_RS07380 synthase: epimerase: PD_RS05485 UDP-N-acetyl-α-D-muramoyl-L- phosphotransferase: PD_RS09710Man GlcNAc - PD_RS07375 aminotransferase: PD_RS08255 a malonyl-[acp] PD_RS09665 gamma- 4-phosphate SAH β-D- 6 2 PD_RS09595 PD_RS03960 G: PD_RS04490 PD_RS07385 PD_RS06675 PD_RS00890 aspartate- 4-hydroxy- S-ribosyl-L- α PD_RS05450 alanyl-γ-D-glutamyl-meso-2,6- PD_RS07360 [protein] (isomer 10-(methylsulfanyl) an N 7 - PD_RS00145 1,2-dihydroxy-5- bifunctional (2R)-2,3- glutamyl- -D-glucosamine α-D-glucopyranosyl- mannopyranose (2S)-2- D-xylulose a (2E)-dodec- homocysteine S-acetyldihydrolipoamide glutaryl-CoA NADH CO 527 semialdehyde dihydroxy-3- tetrahydrodipicolinate diaminopimeloyl-D-alanyl-D-alanine UMP 6A B ) 2 -2-oxodecanoate methylguanine oxaloacetate (methylsulfanyl) 3-oxoacyl-ACP synthase phosphoribosyl- 2-oxobutanoate D-ala phosphate aspartate- 6-phosphate formate 1,2 1 isopropylmalate 5-phosphate 2-enoyl-[acp] synthase: PD_RS09165 diphosphoundecaprenol pent-1-en-3-one III: PD_RS04340 dehydrogenase: AMP cyclohydrolase/ methylbutanoate reductase: semialdehyde superpathway of L- in 16S rRNA stearate PD_RS03165 (2S,4S)-4- 3-oxoacyl-ACP synthase phosphoribosyl-ATP 2,3-dihydroxy- acetolactate PD_RS01570 dehydrogenase: asparagine biosynthesis biosynthesis II synthase hydroxy-2,3,4,5- III: PD_RS05510 L-aspartate 4- diphosphatase: isovalerate N-acetyl-L- PD_RS03165 glycine biosynthesis II 34 Man GlcNAc - 34 (bacteria and plants) tetrahydrodipicolinate a 5-carboxymethylaminomethyluridine 8 2 a cytidine D-ribose 5- dehydratase: 2 catalytic 16-hydroxypalmitate NADH menadione H + a cytosine in DNA L-cysteate [DNA] semialdehyde PD_RS06680 glutamate 5- L-aspartate 4- L-homocysteine asp F6P in tRNA Leu [protein] (isomer in tRNA phosphoenol phosphate subunit: 4-hydroxy- ATP a ribonucleic acid dGDP a palmitoyl-[acp] an acetoacetyl-[acp] 1-(5-phospho-β-D-ribosyl)- PD_RS00410 semialdehyde semialdehyde a [glycine-cleavage complex long-chain fatty acid-- tRNA (cytidine(34) 8A Balpha-1,2-) NADH-quinone tRNA (cytidine(34) aspartate/ pyruvate DNA ribose-5- a dodecanoyl-[acp] bifunctional tetrahydrodipicolinate gly 1,2,3 2,3 DNA cytosine pyruvate 3-oxoacyl-ACP 5-[(5-phosphoribosylamino) 3-methyl-2- PD_RS05490 6 CoA ligase: PD_RS01230 -2'-O)- polynucleotide oxidoreductase -2'-O)- tyrosine/aromatic polymerase: phosphate aspartate kinase/ reductase: PD_RS02080 bifunctional H protein] N -lipoyl-L-lysine mannosidase: methyltransferase: kinase: synthase III: methylideneamino]imidazole- oxobutanoate acetolactate asparagine asparagine glycine dehydrogenase methyltransferase: adenylyltransferase subunit H: methyltransferase: aminotransferase: PD_RS05980 isomerase: homoserine (S)-2,3,4,5- hydrogencarbonate aspartate kinase/ Inorganic Nutrient Metabolism PD_RS09710Man GlcNAc - PD_RS03005 PD_RS09785 PD_RS05510 4-carboxamide synthase: synthase synthase (aminomethyl-transferring) AMP diphosphate 16-hydroxypalmitoyl-CoA PD_RS04330 β-D- 7 2 PcnB: PD_RS00975 PD_RS01370 PD_RS04330 PD_RS00145 [+ 2 isozymes] PD_RS04155 beta-ketoacyl- dehydrogenase tetrahydrodipicolinate superpathway of L-methionine homoserine [protein] (isomer a 5-methylcytosine a 2'-O- D-ribulose 2-isopropylmalate PD_RS05495 N-acetyl-L- B: asnB B: asnB : PD_RS03225 a 5-carboxymethylaminomethyl- mannopyranose a ribonucleic acid + dGTP pyruvate a nucleoside 5'- [acyl-carrier- [+ 2 isozymes] I: PD_RS06740 1-(5-phosphoribosyl) branched-chain carbamoyl- superpathway of sulfate assimilation 7A B ) menadiol NAD in DNA methylcytidine 34 3-sulfopyruvate a 3-oxooctadecanoyl- 2,3,4,5- biosynthesis (by sulfhydrylation) ornithine dehydrogenase L-cystathionine 2'-O-methyluridine 34 in tRNA Leu 1,2,3 2 5-phosphate protein] -5-((5- synthase: amino acid (S)-2-aceto-2- phosphate glycine cleavage system and cysteine biosynthesis in tRNA monophosphate laurate [acp] PD_RS05505 tetrahydropyridine- I: PD_RS06740 protein H: PD_RS00790 synthase II: L-homoserine phosphoribosylamino) aminotransferase: hydroxybutanoate oxaloacetate synthase: acetylornithine O-succinylhomoserine 3-oxoacyl-ACP fatty acid elongation -- saturated 2,6-dicarboxylate N- asn asn CO PD_RS07905 methylideneamino) PD_RS04220 ketol-acid PD_RS02085 deacetylase: L-homoserine (thiol)-lyase: 2 3-phospho-D-glycerate long-chain reductase succinyltransferase: sulfate 4a-hydroxy-N 10 - Man GlcNAc - Man GlcNAc - a uracil 1939 a uracil 1498 homoserine imidazole-4- (2S)-2- reductoisomerase: aspartate/ carB PD_RS01560 7 2 7 2 a phosphate [+ 2 isozymes] fatty acid-- PD_RS00470 PD_RS09610 (15Z)-tetracosenoate [protein] (isomer [protein] (isomer asp fumarate Ins(2)P phosphoenol glu ala FabG: an acetoacetyl-[acp] kinase: carboxamide isomerase: isopropylmalate PD_RS05485 tyrosine/aromatic homoserine sulfate phosphoglycerate formyltetrahydrofolate in 23S rRNA in 16S rRNA dADP monoester CoA ligase: PD_RS00755 val N-succinyl-2-amino- carbamoyl dehydrogenase: long-chain fatty acid-- 7A B alpha-1,2-) 7A Balpha-1,2-) 23S rRNA 16S rRNA pyruvate PD_RS06735 PD_RS06690 3-isopropylmalate aminotransferase: L-ornithine kinase: cys adenylyltransferase 1,2 1,2 1,2,3 3 L-aspartate inositol pyruvate glutamate- alkaline a 3-oxotetradecanoyl- PD_RS01230 (R)-2,3-dihydroxy- phosphate CoA ligase: PD_RS01230 4a-hydroxytetrahydrobiopterin (uracil(1939)-C(5)) (uracil(1498)-N(3))- 3-oxoacyl- dehydratase: 6-ketopimelate PD_RS00145 PD_RS06650 mannosidase: mannosidase: oxidase: monophosphatase: -cysteine phosphatase: [acp] O-phospho- phosphoribulosylformimino- 3-methylpentanoate PD_RS06735 subunit 2: PD_RS03730 dehydratase: PD_RS10475 -methyltransferase methyltransferase: kinase: ACP PD_RS07380 L-glutamate PD_RS09710Man GlcNAc - PD_RS09710Man GlcNAc PD_RS04535 PD_RS07870 ligase: PD_RS07975 lauroyl-CoA L-homoserine AICAR-phosphate β-D- 6 2 β-D- 6 2 PD_RS09785 2,3-dihydroxy-3- ornithine α O-phospho- biosynthesis II 3-phosphooxypyruvate AMP diphosphate (15Z)-tetracosenoyl-CoA 10 RlmD: PD_RS07315 3 PD_RS00830 3-oxoacyl-ACP asp S-methyl-5-thio- -D-ribose APS an N -formyl- [protein] (isomer -[protein] 1939 succinate 2-iminosuccinate an N - PD_RS03410 reductase PD_RS07385 mannopyranose mannopyranose a 5-methyluracil dATP pyruvate γ threonine methylvalerate carbamoyltransferase: L-homoserine 1498 myo-inositol -L-glutamyl- an alcohol reductase FabG: fabG 1-phosphate degradation I phosphoserine 7,8-dihydrofolate 6A B ) (isomer 6A ) methyluracil a 3-oxoacyl-[acp] synthase: imidazole glycerol hydro-lyase: N-succinyl-L,L-2,6- PD_RS01550 2-oxoglutarate adenylyl-sulfate 1,2 2 1,2,3 in 23S rRNA D-alanine FabG: a (3R)-3- 2-isopropylmaleate bifunctional threonine aminotransferase: in 16S rRNA 3-oxoacyl-ACP PD_RS06730 phosphate synthase: PD_RS00410 diaminopimelate glutamate kinase: PD_RS03735 PD_RS00755 hydroxyoctadecanoyl- aspartate kinase/ 5-MTR-1-P synthase: PD_RS07180 reductase PD_RS06685 3-isopropylmalate (S)-3-methyl-2- succinyl- PD_RS06730 superpathway of aromatic amino acid biosynthesis dehydrogenase: 3-oxoacyl- [acp] thr homoserine Man GlcNAc - Man GlcNAc - FabG: fabG PD_RS06695 dehydratase: oxopentanoate diaminopimelate L-citrulline S-methyl-5- PD_RS04090 PAPS 3-aci- 8 2 6 2 a 5' triphospho- O-ureido-L- (S)-2- an aromatic a D-hexose ACP dehydrogenase O-phospho-L-serine 18-hydroxystearate [protein] (isomer [protein] (isomer asp glu Ins(1)P thr 3-oxoacyl-ACP PD_RS07380 desuccinylase: sulfate thioribose-1- thr glu nitropropanoate [mRNA] homoserine aminobutanoate amino acid reductase 3-oxoacyl-ACP branched-chain I: PD_RS06740 chorismate phosphoadenosine long-chain fatty acid-- nitronate 8A B ) 6A B ) reductase FabG: threonine/ PD_RS07385 PD_RS00480 argininosuccinate phosphate 1,2,3 alpha-1,2-1,2 1,2 alpha-1,2-1 RNA argininosuccinate glutamate- inositol aspartate/ threonine/ glucokinase: FabG: fabG synthase III: AICAR D-erythro-imidazole- amino acid phosphosulfate monooxygenase: PD_RS00755 serine (2R,3S)-3- L-aspartyl- sulfate synthase: CoA ligase: PD_RS01230 mannosidase: mannosidase: pyrophosphohydrolase: synthase: -cysteine tyrosine/aromatic serine PD_RS01820 a (3R)-3- a (2E)-octadec- PD_RS05510 glycerol-phosphate aminotransferase: isomerase: reductase: PD_RS03715 PD_RS00495 monophosphatase: 2-enoyl-[acp] dehydratase: isopropylmalate L,L-diaminopimelate 4-phosphate adenylyltransferase PD_RS01555 PD_RS10255 anthranilate synthase: chorismate mutase: [unspecified PD_RS09710Man GlcNAc - PD_RS09710Man GlcNAc PD_RS08800 PD_RS01555 ligase: PD_RS07870 aminotransferase: dehydratase: hydroxytetradecanoyl- a 2,3,4-saturated[+ 2 isozymes] a (3R)-3-hydroxyacyl- bifunctional histidinol- PD_RS04220 subunit 2: AMP diphosphate 18-hydroxystearoyl-CoA β-D- 7 2 β-D- 5 2 PD_RS05500 3-isopropylmalate L-arginino- PD_RS00900 PD_RS07175 sulfite degradation nitrite 3-oxopropanoate [protein] (isomer -[protein] a 5'-phospho- canavaninosuccinate PD_RS03410 PD_RS00145 PD_RS05500 D-hexose 6- [acp] fatty acyl-[acp] [acyl-carrier protein] phosphatase/ aspartate- PD_RS03730 5-(methylsulfanyl)- mannopyranose mannopyranose γ-L-glutamyl-(S)- myo-inositol an aromatic (2Z)-2-aminobut- dehydrogenase: diaminopimelate succinate ser products] 7A B ) (isomer 5A ) [mRNA] 2-oxobutanoate phosphate (3R)-3- imidazoleglycerol- ile semialdehyde ribulose 1-phosphate 1,2 1,2 1,2 2-aminobutanoate 2-oxo-acid 2-enoate PD_RS07375 epimerase: APS PRPP anthranilate prephenate assimilatory sulfite hydroxymyristoyl- phosphate dehydrogenase: argininosuccinate methylthioribulose (2S)-2-isopropyl- PD_RS03640 reductase (NADPH) [acyl-carrier dehydratase: PD_RS03165 lyase: PD_RS01575 1-phosphate a stearoyl-[acp] 3-oxosuccinate adenylyl- anthranilate : PD_RS03720 an N-formyl-L- Man GlcNAc - a double-stranded a peptide with protein] PD_RS06700 meso-diaminopimelate a proteinogenic 8 2 γ-L-glutamyl-(S)- long chain L-aspartate 4- sulfate kinase: dehydratase: phosphoribosyltransferase: prephenate prephenate PD_RS03725 (2E)-hexadecenoate leukotriene-C4 methionylaminoacyl- [protein] (isomer a peptide gly an N-terminal an oligopeptide MeOH dehydratase: arg amino acid 2-aminobutanoate oligonucleotide polyphosphate 2-iminobutanoate semialdehyde PD_RS03735 PD_RS06665 PD_RS00905 dehydratase: dehydrogenase/ long-chain fatty acid-- tRNA 8A B ) L-proline PD_RS08255 L-proline O-acetyl-L-serine gamma- peptide 1,2,3 alpha-1,2-1,3 Xaa-Pro proline catalase- imidazole acetol-phosphate diaminopimelate PD_RS07175 arogenate hydrogen sulfide glutathione oligoribonuclease: oligopeptidase polyphosphate a 2,3,4-saturated a trans-2-enoyl- biosynthesis I decarboxylase: bifunctional 5-(methylsulfanyl)-2,3- CoA ligase: PD_RS01230 glutamyltransferase: deformylase: mannosidase: aminopeptidase: synthetase: iminopeptidase: peroxidase: a (2E)-tetradec- PAPS N-(5-phosphoribosyl)-anthranilate dehydrogenase family PD_RS02725 B: PD_RS03635 kinase: fatty acyl-[acp] [acyl-carrier protein] histidinol-phosphate 4-methyl-2- PD_RS02135 aspartate kinase/ dioxopentyl 1-phosphate PD_RS01490 PD_RS09305 PD_RS09710Man GlcNAc PD_RS04185 PD_RS04395 PD_RS03780 PD_RS06770 β 5 2 PD_RS10415 2-enoyl-[acp] stearate aminotransferase: oxopentanoate homoserine 3-phenyl-2-oxopropanoate protein: PD_RS07230 cysteine synthase AMP diphosphate (2E)-hexadecenoyl-CoA an α-(γ-L-glutamyl) a L-methionylaminoacyl- -D- a proteinogenic glu phosphoadenosine acireductone N-(5'-phosphoribosyl) leukotriene-D4 formate -[protein] a peptide ophthalmate a nucleoside 5'- a peptide pro A: PD_RS09760 -L-amino acid tRNA mannopyranose amino acid a peptide long chain formaldehyde long-chain PD_RS06705 branched-chain glutamate lys dehydrogenase phosphosulfate synthase: anthranilate isomerase: (isomer 5A ) monophosphate 2-oxobutanoate L-alanine aspartate/ 1,2 polyphosphate fatty acid-- amino acid 5-kinase: I: PD_RS06740 reductase: PD_RS06675 PD_RS03180 3-(4-hydroxyphenyl)pyruvate cysteine synthase: selenate reduction L-histidinol phosphate biosynthesis III 2-hydroxy-5- tyrosine/aromatic CoA ligase: acetolactate aminotransferase: PD_RS01580 PD_RS03715 1-(2-carboxyphenylamino)-1- PD_RS00530 γ-L-glutamyl (methylsulfanyl)-3-oxopent- aminotransferase: aspartate/ PD_RS01230 synthase PD_RS04220 L-homoserine deoxy-D-ribulose 5-phosphate selenate a single- Man GlcNAc - 3-[(4'- a [protein]-L- a myristoyl-[acp] bifunctional histidinol- 5-phosphate sulfite cys PD_RS00145 2,3,6- 9 2 (2R,3S)-3- 1-enyl 1-phosphate tyrosine/aromatic 18-hydroxyoleate glutathione [protein] (isomer uroporphyrinogen-III glutathione methylmercury methylsulfanyl) an oligopeptide ω ethanol 2 catalytic phosphatase/ homoserine O- cysteine acireductone indole-3-glycerol- cys sulfate stranded RNA trichlorohydroquinone isopropylmalate proline ( = 180) stearoyl-CoA leu gamma- superpathway of L-serine aminotransferase: long-chain fatty acid-- polyribonucleotide glutathione S- 9A B ) glutathione S- butyl]malate peptidylprolyl beta-ketoacyl- subunit: assimilatory desulfurase: phosphate adenylyltransferase 1,2,3 alpha-1,2-1,2,3 uroporphyrinogen III 3-isopropylmalate catalase- imidazoleglycerol- glutamyl- and glycine biosynthesis I acetyltransferase: synthase: phe PD_RS00145 nucleotidyltransferase: transferase: transferase: 3-isopropylmalate oligopeptidase isomerase: [acyl-carrier- PD_RS05490 sulfite PD_RS03605 synthase: trpC subunit 2: CoA ligase: PD_RS01230 mannosidase: methyltransferase: dehydrogenase: peroxidase: phosphate phosphate PD_RS07825 PD_RS06675 PD_RS01040 PD_RS02560 PD_RS02560 dehydrogenase: A: PD_RS00525 PD_RS02570 protein] acetolactate dehydratase: 3-phospho- reductase ala 1,2-dihydroxy-5- adenosine 5'-PD_RS03730 2,6-dichloro-3- PD_RS09710Man GlcNAc PD_RS05610 PD_RS07375 PD_RS06770 reductase: homoserine O- (1S,2R)-1-C-(indol-3- tyr AMP diphosphate 18-hydroxyoleoyl-CoA a nucleoside a single- β-D- 5 2 methylmercury- PD_RS07375 synthase II: synthase: D-glycerate (NADPH): (methylsulfanyl) (glutathion-S-yl) -[protein] 4-methyl-2- [+ 4 isozymes] phosphatidylglycerol PD_RS06700 PD_RS01585 phosphoglycerate acetyltransferase: yl)glycerol 3-phosphate phosphoselenate diphosphate stranded RNA mannopyranose precorrin-2 S-glutatione 7-(methylsulfanyl) a peptide a [protein]-L- acetaldehyde PD_RS07905 PD_RS05495 PD_RS03720 pent-1-en-3-one -hydroquinone (isomer 5A ) oxopentanoate biosynthesis II L-cysteine dehydrogenase: PD_RS09615 1,2 -2-oxoheptanoate proline (ω = 0) histidinol [+ 2 isozymes] (non-plastidic) (S)-2-aceto-2- biosynthesis I L-glutamate-5- PD_RS06650 PD_RS03725 tryptophan synthase: semialdehyde O-acetyl-L- PD_RS03185 a 3-oxohexadecanoyl- hydroxybutanoate 3-phosphooxypyruvate DHAP histidinol homoserine hydrogen sulfide PD_RS03190 (7R)-7-(4- 3-[(3'- [acp] ketol-acid dehydrogenase: ser 4-(methylsulfanyl) selenite a ribonucleic acid an N-modified 1-chloro-2,4- N-acetyl- DNA with lesion wound RNA phosphoenol glycerol-3- phosphoserine tryptophan S-adenosyl-L-methionine cycle I 7-hydroxylaurate glutathione hypoglycin A carboxybutanamido) glutathione methylsulfanyl) reductoisomerase: PD_RS06710 -2-oxobutanoate aminoacyl-[tRNA] dinitrobenzene L-citrulline pyruvate 3-oxoacyl-ACP phosphate aminotransferase: O-acetylhomoserine synthase subunit long-chain fatty acid-- cephalosporanate ribonuclease glutathione S- propyl]malate excinuclease RNA helicase: PD_RS05485 gamma- glutaryl-7- peptidyl-tRNA 3-isopropylmalate acetylornithine pyruvate reductase dehydrogenase histidinal (S)-1-pyrroline- PD_RS07180 sulfhydrylase: beta: PD_RS03185 CoA ligase: PD_RS01230 PH: transferase: ABC subunit C: PD_RS01085 (R)-2,3-dihydroxy- 2-oxo-4- glutamyltransferase: ACA acylase: hydrolase: dehydrogenase: deacetylase: kinase: FabG: (NAD(P)(+)): O-acetyl-L-serine 5-carboxylate PD_RS09610 SAM PD_RS03755 PD_RS02560 PD_RS07010 RNA helicase: 3-methylpentanoate O-phospho- L-glutamate methylthiobutanoate- PD_RS01490 PD_RS01670 PD_RS10650 2,4-dinitrophenyl- PD_RS07375 PD_RS01560 PD_RS09785 PD_RS00755 PD_RS05590 L-glutamate histidinol pyrroline-5- ser indole selenodiglutathione AMP diphosphate 7-hydroxylauroyl-CoA (7R)-7 a nucleoside a ribonucleic acid an N-modified an uncharged [+ 3 isozymes] PD_RS10835 sn-glycerol 2,3-dihydroxy-3- L-serine biosynthesis I glutamine L-cysteinylglycine hypoglycin B glutarate diphosphate S-glutathione 6-(methylsulfanyl) acetate L-citrulline DNA without pyruvate 3-oxoacyl- biosynthesis III dehydrogenase: cysteine carboxylate S-adenosylmethionine aminocephalosporanate amino acid tRNA an unwound RNA 3-phosphate methylvalerate aminotransferase: -2-oxohexanoate lesion ACP PD_RS06710 synthase A: reductase: L-homocysteine tryptophan synthase: glycerol-3- hydro-lyase: gln PD_RS07775 reductase 2-oxoglutarate PD_RS09760 PD_RS10890 synthase subunit PD_RS08815 FabG: fabG phosphate 1-O- PD_RS00410 glutamate his glutamate 5-methyltetrahydropteroyltriglutamate- beta: PD_RS03185 3-[(5'- cysteine met SAH a 2,3,4-saturated RNase III mRNA a [protein] N-terminal- γ a 3α- a supercoiled a (3R)-3- acyltransferase: (S)-3-methyl-2- synthase synthase - homocysteine 2-oxoglutaramate glutathioselenol 2-methylbutanoate a single a ribonucleoside a [ThiI sulfur-carrier -L-glutamyl- ferroheme o synthase: pro ser met CTP 1,2-diacyl-sn- processing cys formyl-L-methionine methylsulfanyl) gly hydroxysteroid duplex DNA hydroxyhexadecanoyl- PD_RS01675 oxopentanoate subunit beta: subunit beta: methyltransferase: PD_RS06915 stranded DNA triphosphate protein]-L-cysteine D-alanine a 1-acyl-sn PD_RS00530 trp acetyl-coenzyme A glycerol 3-phosphatephosphatidate substrate DNA primase: cysteine peptide pentyl]malate glutathione 3-alpha- replicative heme A [acp] PD_RS10880 PD_RS10880 ribonuclease 3: 3-isopropylmalate -glycerol 3- branched-chain serine synthetase: PD_RS06860 cytidylyltransferase: PD_RS04115 desulfurase: deformylase: synthetase: hydroxysteroid DNA helicase: synthase: (3R)-3- glu met 5-methyltetrahydropteroyltriglutamate- PD_RS06830 dehydrogenase: phosphate amino acid glutamate cys hydroxymethyltransferase: glyA PD_RS01745 RNase III [+ 2 isozymes] PD_RS03605 PD_RS09305 PD_RS04395 dehydrogenase: PD_RS08935 PD_RS03115 hydroxypalmitoyl- aminotransferase: dehydrogenase: - homocysteine a CDP-2,3,4-saturated- an mRNA fragment processing ssDNA/pppN(pN) a [ThiI sulfur- an N-terminal L- PD_RS07375 hydrogen selenide 2-methylbutanoyl-CoA AMP diphosphate formate norophthalmate PD_RS06905 [+ 2 isozymes] [acyl-carrier PD_RS04220 PD_RS04090 2-oxoglutarate methyltransferase: PD_RS06915 S-ribosyl-L- diacylglycerol product mRNA hybrid carrier protein]-S- ala methionyl-[protein] 8-(methylsulfanyl) a single ferroheme a L-homocysteine n -1 a 3-oxosteroid gly homocysteine sulfanyl-L-cysteine -2-oxooctanoate stranded DNA protein] glu dehydratase: a 1,2-diacyl- ile PD_RS08255 sn-glycerol GlcMan GlcNAc 3-[(6'- γ 3-phosphate a single 7,8-dihydrofolate 9 2 dihomo - an organic urea cycle NADPH H + a peptide with a a uracil in DNA methylsulfanyl) H O D-ribofuranose a (2E)-hexadec- phosphatidate stranded DNA O-acetyl-L-serine hydrogen selenide monoglutamate -[protein] linolenoyl-CoA 2 D-ala hydroperoxide 2-enoyl-[acp] exodeoxyribonuclease dihydrofolate leader sequence alpha-1,2- uracil-DNA hexyl]malate acyl-CoA peroxiredoxin: cytidylyltransferase: cysteine synthase: signal peptidase VII large subunit: reductase: mannosidase: glycosylase: 3-isopropylmalate thioesterase II: D-alanine--D- PD_RS03865 ribokinase: PD_RS01745 arg PD_RS00530 I: PD_RS06820 PD_RS10065 PD_RS07205 PD_RS09710 PD_RS10815 dehydrogenase: PD_RS01655 alanine ligase: peroxiredoxin: PD_RS08925 D-glucosyl- Man GlcNAc - γ a CDP- a single-stranded a ribonucleoside 5,6,7,8- 8 2 an apyrimidinic PD_RS07375 di-homo- - PD_RS09880 acetate L-selenocysteine NADP + a leader sequence a peptide α α uracil PD_RS09175 D-ribofuranose diacylglycerol oligodeoxyribonucleotide 5'-monophosphate tetrahydrofolate (1->3)- - [protein] (isomer site in DNA 9-(methylsulfanyl) linolenate ammonium D-mannose 8A B ) D-alanyl-D-alanine an alcohol 5-phosphate a palmitoyl-[acp] CDP-diacylglycerol-- argininosuccinate 1,2,3 1,2 -2-oxononanoate glycerol-3-phosphate 3- lyase: PD_RS01575 carbamoyl- phosphatidyltransferase: phosphate a [glycine-cleavage β 7,8- an (S)-2- acibenzolar- L-gulono- dCTP PD_RS07015 a -D-mannoside 2-phosphoglycolate palmitoyl-CoA H O ethylphosphate L-arginino- synthase: SAM complex H protein] a sulfurated [sulfur carrier] H O diphosphate 2 1,4-lactone 1-(3-sn- L-ornithine dihydromonapterin halocarboxylate 2 S-methyl deoxycytidine PD_RS02085 6 beta- dihydroneopterin haloacid acyl-CoA SMP-30/ phosphatidyl) succinate N -octanoyl-L-lysine inorganic carboxylesterase: phosphoglycolate alkaline triphosphate palmitate carB lipoyl synthase: mannosidase: aldolase: dehalogenase: thioesterase II: gluconolactonase/ -sn-glycerol pyrophosphatase: PD_RS06090 phosphatase: phosphatase: deaminase: PD_RS02765 a [glycine-cleavage PD_RS09690 PD_RS08630 PD_RS03340 PD_RS01655 LRE family protein: long-chain 3-phosphate carbamoyl an unsulfurated β PD_RS06455 MeOH acibenzolar PD_RS07840 PD_RS07975 PD_RS10035 5'-deoxyadenosine met complex H protein] a non glycosylated -D- 6-(hydroxymethyl) a (2R)-2- PD_RS02855 fatty acid-- ornithine phosphate [sulfur carrier] mannopyranose glycolaldehyde a halide anion phosphate H + palmitate N 6 -lipoyl-L-lysine sugar acceptor -7,8-dihydropterin hydroxy fatty acid glycolate ethanol dUTP CoA ligase: argininosuccinate carbamoyltransferase: L-gulonate synthase: PD_RS01230 an L-1- PD_RS01550 PD_RS01555 phosphatidyl- palmitoyl-CoA L-citrulline (5Z,8Z,11Z,14Z,17Z) α-D-galacturonosy- all-trans- CTP sn-glycerol indolylmethylisothiocyanate glutathione coenzyme A glutathione monochlorobimane α an unsulfurated glutathione fenclorim 3-ethylmalate a folate DL-allothreonine -icosapentaenoate (1->4)- -D-galacturonate retinyl palmitate cys deoxycytidine glutathione S- long-chain fatty glutathione S- [sulfur carrier] glutathione S- carboxylesterase: cysteine 3-isopropylmalate dihydrofolate triphosphate Aldehyde Degradation serine transferase: acid--CoA ligase: transferase: polygalacturonase: transferase: PD_RS06090 desulfurase: dehydrogenase: reductase: deaminase: hydroxymethyltransferase: glyA PD_RS02560 PD_RS01230 PD_RS02560 PD_RS07830 PD_RS02560 Fatty Acid and Lipid Degradation palmitate a retinol PD_RS03605 PD_RS07375 PD_RS07205 PD_RS10035 methylglyoxal degradation I gly acetaldehyde indol-3-ylmethylisothiocyanate- (5Z,8Z,11Z,14Z,17Z) (glutathion- a sulfurated 4-(glutathion- D-galactopyranuronate ala glutathione -icosapentaenoyl-CoA S-yl)-bimane [sulfur carrier] S-yl)-fenclorim 2-oxovalerate a 7,8-dihydrofolate UTP methylglyoxal testosterone and androsterone degradation to androstendione lactoylglutathione lyase: PD_RS03270 5,10-methylene- 3-methyl-2- 2,3,5,6- (5Z,8Z,11Z,14Z,17Z) (3E,5Z)-tetradeca- a protein with androsterone glutathione glutathione methylsalicylate a type IV prepilin glutathione RX 2,2-dichloroacetate (S)-malate (R)-S- tetrahydromethanopterin oxobutanoate tetrachlorohydroquinone -icosapentaenoyl-CoA 3,5-dienoyl-CoA a disulfide bond 3-methyl-2-oxobutanoate glutathione S- acyl-CoA acyl-CoA carboxylesterase: glutathione S- lactoylglutathione 3-alpha- glutaredoxin 3: prepilin glutathione S- malate:quinone hydroxymethyltransferase: transferase: thioesterase II: thioesterase II: PD_RS06090 transferase: hydroxyacylglutathione hydroxysteroid PD_RS10435 peptidase: transferase: oxidoreductase: PD_RS00985 PD_RS02560 PD_RS01655 PD_RS01655 a protein with PD_RS02560 hydrolase: PD_RS06430 dehydrogenase: MeOH salicylate PD_RS10185 PD_RS02560 PD_RS09250 2,3,5-trichloro-6-(glutathion- (5Z,8Z,11Z,14Z,17Z) (3E,5Z)- reduced L- GSSG a cleaved type a glutathione- PD_RS06905 THMPT 2-dehydropantoate coenzyme A coenzyme A a peptide HX S-yl)-hydroquinone -icosapentaenoate tetradecadienoate cysteine residues IV prepilin S-conjugate glyoxylate oxaloacetate (R)-lactate 5α-androstane- testosterone 3,17-dione UDP-N-acetyl-α-D-muramoyl- salicyl-6-hydroxy-2- an all-trans UTP 4-hydroxy- a double D-alanyl-D-alanine glutathione glycyl-glycine glutathione stearoyl-CoA H O an L-cysteinyl- L-alanyl-γ-D-glutamyl-L-lysine cyclohexene-on-oyl a tRNA precursor 2 -retinyl ester nucleoside triphosphate 2-nonenal [tRNA Cys ] stranded DNA gamma- carboxylesterase: glutathione S- acyl-CoA pyruvate UDP-N-acetylmuramoyl- carboxylesterase: ribonuclease D: pyrophosphohydrolase: peptidyl-tRNA DNA gyrase tripeptide--D-alanyl-D- glutamyltransferase: PD_RS06090 PD_RS06090 transferase: thioesterase II: androst-4-ene- 6-hydroxy-2- PD_RS10080 PD_RS00810 hydrolase: subunit A: PD_RS01490 PD_RS02560 PD_RS01655 3,17-dione α alanine ligase: PD_RS09905 a fatty acid all-trans-retinol a nucleoside 5'- (glutathion-S- PD_RS10650 PD_RS10250 Detoxification UDP-N-acetyl- -D-muramoyl-L-alanyl- γ-L-glutamyl- salicyl alcohol cyclohexen- a tRNA UMP L-cysteinylglycine stearate Cys γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine glycylglycine one-carboxylate monophosphate yl)-4-hydroxy- a tRNA cys a negatively 2-nonenal supercoiled DNA reactive oxygen species degradation

α UDP-N-acetyl- RNase R degradation superoxide UDP-N-acetyl- -D-muramate dehydro(indole- CTP a kanamycin D-firefly α-D-glucosamine canavaninosuccinate glutathione H O lauroyl-CoA H O a tRNA sec ser UDP-N- substrate RNA 3-yl)acetonitrile nucleoside triphosphate luciferyl-CoA 2 2 UDP-N-acetylglucosamine ribonuclease R: glutathione S- acyl-CoA acyl-CoA superoxide dismutase: acetylenolpyruvoylglucosamine argininosuccinate pyrophosphohydrolase: aminoglycoside serine-- 1-carboxyvinyltransferase: PD_RS04270 transferase: thioesterase II: thioesterase II: PD_RS04545 reductase: PD_RS10340 lyase: PD_RS01575 PD_RS00810 phosphotransferase: tRNA ligase: PD_RS03355 a nucleoside 5'- PD_RS02560 PD_RS01655 PD_RS01655 superoxide dismutase: UDP-N-acetyl-α-D- a diribonucleotide fumarate L-canavanine PD_RS08190 PD_RS06965 UDP-N-acetyl-α-D- monophosphate (glutathion-S-yl)(1H- CMP an L-seryl- PD_RS10515 glucosamine-enolpyruvate a kanamycin D-firefly luciferin laurate glucosamine-enolpyruvate indol-3-yl)acetonitrile 3'-phosphate [tRNA sec ] hydrogen peroxide

a DNA containing methyl (indol- dTTP (2R,3S)-2- (3Z)-hex- catalase-peroxidase: a peptidoglycan [DNA] an apurinic/ a carboxylic ester glutathione oleoyl-CoA H O 2-deoxy-D-ribose 3-yl)acetate nucleoside triphosphate methylisocitrate 3-en-1-ol 2 PD_RS06770 lysozyme: PD_RS05220 apyrimidinic site carboxylesterase: methylisocitrate glutathione S- acyl-CoA exodeoxyribonuclease endonuclease carboxylesterase: pyrophosphohydrolase: muramidase: PD_RS07430 I: PD_RS04130 PD_RS06090 PD_RS06090 lyase: transferase: thioesterase II: ribokinase: [DNA] RS08185 [DNA] H O hydroxyl radical a N-acetylmuramoyl-pentapeptide- a 2'- III: PD_RS08015 PD_RS00810 PD_RS08925 O 2 N-acetyl-D-glucosamine a 3'-terminal a 5'-phospho- PD_RS02650 PD_RS02560 PD_RS01655 2 diphosphoundecaprenol deoxyribonucleoside [DNA] MeOH (indol-3-yl)acetate a carboxylate an alcohol dTMP 3-(glutathion-S 2-deoxy-D-ribose 5'-monophosphate unsaturated sugar [DNA] pyruvate succinate oleate -yl)-hexan-1-ol 5-phosphate

arsenate oxidized GTP and S-(2-hydroxyacyl) D-sedoheptulose D-glyceraldehyde all-trans- (-)-methyl D-erythrose D-xylulose (+)-7-epi- hydrogen detoxification dGTP detoxification a homogalacturonan H O an acyl-CoA H O A(H2) cellulose glutathione 7-phosphate 3-phosphate retinyl palmitate jasmonate 4-phosphate 5-phosphate jasmonoyl-CoA 2 2 peroxide II (glutaredoxin) polygalacturonase: hydroxyacylglutathione transketolase: carboxylesterase: carboxylesterase: transketolase: acyl-CoA acyl-CoA catalase- endoglucanase: PD_RS07830 arsenate hydrolase: PD_RS06430 PD_RS04485 PD_RS06090 PD_RS06090 PD_RS04485 thioesterase II: thioesterase II: peroxidase: PD_RS09815 dGTP GTP D-xylulose D-ribose 5- D-glyceraldehyde arsenate a homogalacturonan a homogalacturonan a 2-hydroxy glutathione palmitate all-trans-retinol MeOH (-)-jasmonate F6P PD_RS01655 PD_RS01655 PD_RS06770 [+ 2 isozymes] reductase: carboxylate 5-phosphate phosphate 3-phosphate (+)-7-epi- a carboxylate H O A 2 a cellodextrin PD_RS00475 jasmonate arsenite 8-oxo-dGTP 8-oxo-GTP 8-oxo-dGTP diphosphatase: PD_RS02750 8-oxo-GMP arsenite 8-oxo-dGMP

a dicarboxylate a dicarboxylate sulfate phosphate D-glucose cis-vaccenoyl-CoA thiosulfate D-fructose a C4- an amino an amino an amino an amino an amino an a lipopolysaccharide a lipopolysaccharide a nucleotide a sulfonate a 2,3,4-saturated fatty acyl CoA sulfate a polysaccharide 1-phosphate dicarboxylate a carbohydrate D-galactose acid acid acid acid acid oligopeptide a lipopolysaccharide phosphate predicted predicted predicted ABC predicted ABC ABC ABC RS01230 RS03075 RS07370 RS03300 efflux transporter of efflux transporter of RS03330 RS01455 RS07725 RS03555 RS07245 RS08745 RS06660 RS06655 RS07980 RS04480 RS08750 RS06360 RS06885 transporter transporter a lipopolysaccharide a lipopolysaccharide of sulfate of phosphate a C4- cis-vaccenate thiosulfate a polysaccharide D-fructose a carbohydrate a nucleotide a sulfonate an amino an amino an amino an dicarboxylate a 2,3,4-saturated fatty acid sulfate a lipopolysaccharide D-galactose acid acid an amino an amino acid phosphate oligopeptide sulfate a lipopolysaccharide a lipopolysaccharide D-glucose acid acid phosphate a dicarboxylate a dicarboxylate This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.