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Mesoporous Polydopamine Nanoparticles Carrying Peptide RL-QN15 Show Potential for Skin Wound Therapy
Mesoporous Polydopamine Nanoparticles Carrying Peptide RL-QN15 Show Potential for Skin Wound Therapy Pan Qin Kunming Medical University Yi Meng Kunming Medical University Ying Wang Yunnan Minzu University Xinyu Gou Shaanxi Normal University Naixin Liu Kunming Medical University Saige Yin Kunming Medical University Yan Hu Kunming Medical University Huiling Sun Kunming Medical University Zhe Fu Kunming Medical University Yinlei Wang Kunming Medical University Xiaojie Li Kunming Medical University Jing Tang Kunming Medical University Ying Yang Kunming Medical College Fourth Aliated Hospital Ziwei Deng Shaanxi Normal University Xinwang Yang ( [email protected] ) Kunming Medical University https://orcid.org/0000-0003-3210-8908 Page 1/28 Research Keywords: wound healing, mesoporous polydopamine, RL-QN15, nanoparticles Posted Date: April 28th, 2021 DOI: https://doi.org/10.21203/rs.3.rs-437830/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 2/28 Abstract Background: Skin wound healing remains a considerable clinical challenge, thus stressing the urgent need for the development of new interventions to promote repair. Recent researches indicate that both peptides and nanoparticles may be potential therapies for the treatment of skin wounds. Methods: In the current study, the mesoporous polydopamine (MPDA) nanoparticles were prepared and the peptide RL-QN15 that was previously identied from amphibian skin secretions and exhibited signicant potential as a novel prohealing agent was successfully loaded onto the MPDA nanoparticles, which was conrmed by results of analysis of scanning electron microscopy and fourier transform infrared spectroscopy. The encapsulation eciency and sustained release rate of RL-QN15 from the nanocomposites were determined. -
Construction of Water Environment Carrying Capacity
International Conference on Economics, Social Science, Arts, Education and Management Engineering (ESSAEME 2015) Construction of Water Environment Carrying Capacity Evaluation Model in Erhai River Basin Liu Wei-Hong1,2, Zhang Cheng-Gui1,3 , Gao Peng-Fei1,3,Liu Heng1,3,Song Yan-Qiu1, Huang Bi-Sheng4, Yang Jian-Fang*1,5 1 The Key Laboratory of Medical Insects and Spiders Resources for Development & Utilization at Yunnan Province; Dali University, Dali 671000, Yunnan Province, China; 2The Libraries of Dali University, Dali 671000, Yunnan Province, China; 3 National-local Joint Engineering Research Center of Entomoceutics, Dali 671000, Yunnan Province, China 4Department of Agriculture and Biological Sciences,Dali University, Dali 671003, People’s Republic of China 5School of Foreign Languages, Dali University, Dali 671000, Yunnan Province, China; Liu Wei-Hong and Zhang Cheng-Gui have contributed equally to this work. *Corresponding author: Associate Professor Yang Jian-Fang The Key Laboratory of Medical Insects and Spiders Resources for Development & Utilization at Yunnan Province; Dali University, Dali 671000, Yunnan Province, China; E-mail: [email protected] Keywords: Water environment carrying capacity, Evaluation model, Erhai River basin. Abstract. With the acceleration of urbanization and increasing energy consumption in China, the intensity of pollution emission the pollution load is increasing significantly. In many rivers, the main pollutant load is much more than the environmental capacity of the water, resulting in the destruction of the structure and function of the river basin. This paper puts forward the concept of water environment carrying capacity, and constructs the basic model of calculating water environment carrying capacity, and then takes ErhaiRiver as an example to calculate the carrying capacity of water environment in order to provide reference for relevant researchers. -
FORMATO PDF Ranking Instituciones Acadã©Micas Por Sub Ã
Ranking Instituciones Académicas por sub área OCDE 2020 1. Cs. Naturales > 1.07 Otras Ciencias Naturales PAÍS INSTITUCIÓN RANKING PUNTAJE USA Harvard University 1 5,000 USA Massachusetts Institute of Technology (MIT) 2 5,000 USA Stanford University 3 5,000 UNITED KINGDOM University of Cambridge 4 5,000 USA Columbia University 5 5,000 USA University of California Berkeley 6 5,000 UNITED KINGDOM University of Oxford 7 5,000 UNITED KINGDOM University College London 8 5,000 USA Yale University 9 5,000 USA University of California Los Angeles 10 5,000 USA Johns Hopkins University 11 5,000 USA University of Washington Seattle 12 5,000 USA University of California San Diego 13 5,000 USA University of Chicago 14 5,000 UNITED KINGDOM Imperial College London 15 5,000 USA University of California San Francisco 16 5,000 USA Northeastern University 17 5,000 USA Cornell University 18 5,000 CHINA Peking University 19 5,000 AUSTRALIA University of Queensland 20 5,000 DENMARK University of Copenhagen 21 5,000 USA Princeton University 22 5,000 JAPAN University of Tokyo 23 5,000 SINGAPORE National University of Singapore 24 5,000 USA University of Pennsylvania 25 5,000 CANADA University of Toronto 26 5,000 FRANCE Universite Paris Saclay 27 5,000 UNITED KINGDOM University of Edinburgh 28 5,000 SWITZERLAND ETH Zurich 29 5,000 USA Duke University 30 5,000 USA Arizona State University 31 5,000 CANADA University of British Columbia 32 5,000 FRANCE Universite de Toulouse 33 5,000 FRANCE Sorbonne Universite 34 5,000 USA Georgia Institute of Technology 35 5,000 USA University of Michigan 36 5,000 USA University of Maryland College Park 37 5,000 FRANCE Universite Toulouse III - Paul Sabatier 38 5,000 UNITED KINGDOM University of Bristol 39 5,000 CANADA McGill University 40 5,000 USA University of California Santa Barbara 41 5,000 GERMANY Ruprecht Karls University Heidelberg 42 5,000 NETHERLANDS Utrecht University 43 5,000 USA New York University 44 5,000 USA University of Minnesota Twin Cities 45 5,000 CHINA Tsinghua University 46 5,000 USA Harvard T.H. -
Conference Program Organizing Committee
Conference Program GMSARN Board Members Dr. OM Romny Day 1 Afternoon: Opening & Keynote, Parallel Sessions Director General, Institute of Technology of Cambodia, Day 2 Technical Visit (Optional) Cambodia Welcome Dinner Prof. Lav Chhiv Eav Day 3 Morning: Keynote & Parallel Sessions Rector, The Royal University of Phnom Penh, Cambodia Afternoon: Parallel Sessions & Closing Prof. Zhou Rong President, Kunming University of Science and Technol- th ogy, Yunnan, China The GMSARN International Organizing Committee Prof. HE Tianchun President, Yunnan University, Yunnan, China Chair: Prof. Worsak Kanok -Nukulchai, Acting President, 8 Conference 2013 Prof. Tang Jiliang Asian Institute of Technology President, Guangxi University, China Co-chairs: Prof. Mya Mya Oo, Rector, Yangon Technological Prof. Dr. Soukkongseng Saignaleuth University & Mandalay Technological University President, National University of Laos, Vientiane, Lao PDR Members: Prof. Dr. Mya Mya Oo H.E. Prof. LAV Chhiv Eav, President, Royal University of Phnom Rector, Yangon Technological University, Myanmar Penh Prof. Dr. Nguyen Trong Giang Dr. OM Romny, Director General, Institute of Technology President, Hanoi University of Science and Technology, of Cambodia Hanoi, Vietnam Assoc. Prof. Dr. Taweep Chaisomphop, Vice Rector for Academic Assoc. Prof. Dr. Vu Dinh Thanh Affairs, Thammasat University Rector, Ho Chi Minh City University of Technology, Ho Asst. Prof. Dr. Apisak Dhiravisit, Assistant to the President for Tech- Chi Minh City, Vietnam nology Transfer Affairs, Khon Kaen University Prof. Dr. Somkit Lertpaithoon Prof. Dr. Xiao Xian, Vice President, Yunnan University Rector, Thammasat University, Bangkok, Thailand Prof. DENG Gang, Director, Division of International Cooperation, Assoc. Prof. Dr. Kittichai Triratanasirichai Kunming University of Science and Technology President, Khon Kaen University, Khon Kaen, Thailand Prof. -
Full Text Via the Platform
PREFACE Dear Distinguished Delegates and Guests, The 3rd International Conference on Green Power, Materials and Manufacturing Technology and Applications (GPMMTA2013) was held in Wuhan, China, from December 27-30, 2013, serving as a platform for expertise exchange. GPMMTA2013 had drawn the attention of researchers from various disciplines: Green Power, Materials, Manufacturing Technology, Mechanical Engineering, Electronic Engineering, Automation and Control, etc. Persons who attended the conference were engineers, scientists, managers of various companies and professors of the universities abroad and home. We have had record number of submission 735 this year. From which 239 papers have been accepted for presentation at the conference and will be published by TTP, in Applied Mechanics and Materials (ISSN: 1660-9336), which is online available in full text via the platform www.scientific.net. AMM should be indexed by EI according the previous TTP index results. We express our special gratitude to all the members of the General Committee Chairs, Program Committee Chairs, Technical Program Committee and Steering Committee who worked so hard to prepare the conference and who supported the conference so professionally. The 3rd International Conference on Green Power, Materials and Manufacturing Technology and Applications (GPMMTA2013) is organized by Yunan University, Electric Power Research Institute of YNPG, Huazhong Agricultural University, Southwest Forestry University, Jinan University, Shanghai Jiao Tong University, Nanyang Technological University, Tsinghua University, Hunan Institute of Engineering, and sponsored by National Natural Science Foundation of China (NSFC), Provincial Natural Science Foundation of Hunan (13JJ9022), Provincial Science & Technology plan project of Hunan(2013GK3029). Their kind support makes GPMMTA2013 become possible. Especially, we should thank the TTP. -
1Ec77e117e2ce3cf999f0ab38d9f
Electronic Supplementary Material (ESI) for RSC Advances. This journal is © The Royal Society of Chemistry 2018 Electronic supplementary information (ESI) Insights into the role of electrostatics in temperature adaptation: A comparative study of psychrophilic, mesophilic, and thermophilic subtilisin-like serine proteases Yuan-Ling Xia,‡a Jian-Hong Sun,‡a Shi-Meng Ai,b Yi Li,a Xing Du,a Peng Sang,c Li-Quan Yang,c Yun-Xin Fu*a,d and Shu-Qun Liu*a,e aState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, Yunnan, P.R. China bDepartment of Applied Mathematics, Yunnan Agricultural University, Kunming, Yunnan, P. R. China cCollege of Agriculture and Biological Science, Dali University, Dali, Yunnan, P. R. China dHuman Genetics Center and Division of Biostatistics, School of Public Health, the University of Texas Health Science Center, Houston, Texas, USA eKey Laboratory for Tumor molecular biology of High Education in Yunnan Province, School of Life Sciences, Yunnan University, Kunming, Yunnan, P. R. China ‡ These authors contributed equally to this work * Corresponding author Email: [email protected] (YXF), [email protected] (SQL) Fig. S1 Structure-based multiple sequence alignment of the psychrophilic VPR, mesophilic PRK, and thermophilic AQN. Protein secondary structure (SS) is shown below the alignment, with H, E, and L/l representing the -helix (or 3/10 helix), -strand, and loop, respectively. Residue insertion and deletion are denoted by lowercase single-letter amino acid code and ‘-‘, respectively. The charged residues are highlighted in grey. † Table S1 pKa values of histidines in the three protease structures predicted by DelPhiPKa . -
1 Report on the CALA 21 Century Librarian Seminar Project at the 2007 US-SINO Librarians Pragmatic Forum Yunnan Normal Universi
Report on the CALA 21st Century Librarian Seminar Project at the 2007 US-SINO Librarians Pragmatic Forum Yunnan Normal University, Kunming, Yunnan, China, July 9-12, 2007 Sponsored by Yunnan Normal University, CALA, and Yunnan Provincial Library Commission The CALA team includes Guoqing Li (team leader), Barbara Ford, Haiwang Yuan, Shuyong Jiang, Lisa Zhao. Each person had prepared two topics but the Forum only arranged for each to present one. The topics each CALA presenter gave are (titles are not exact): 1. Guoqing Li: • Resources Sharing in the Networked Environment (网络信息环境下图 书馆的信息资源共享模式与运行机制研究) (presented) 2. Barbara Ford: • 21st Century Library Management and Services, Innovations and Developments (21 世纪图书馆管理和服务理念的创新与发展) (presented) • 图书馆馆长在图书馆发展中的地位和作用 3. Haiwang Yuan: • The Building of Models of Library Service Networks (图书馆服务网络 模式的构建) (presented) • 图书馆与和谐社会的建设问题研究 (2nd topic prepared) 4. Shuyong Jiang: • The Value of the Subject Librarian System and Its Effectiveness (学科 馆员制度的价值定位和实效性原则) (presented) • 图书馆人力资源的开发与管理(2nd topic prepared) 5. Lisa Zhao: • Library Role in Preserving Ethnic Culture (图书馆的特色定位与文化 建设研究)(presented) • 图书馆信息共享空间的建设问题研究(2nd topic prepared) There are 5 other speakers from Beijing and Yunnan. The Forum had about 150 attendees who came from different places and institutions: Yunnan province: College of Education College of Finance & Economics 1 Dali Institute Commission of Higher Education of Yunnan Province Honghe Public Library Kunming Army Institute Kunming Institute of Technology Kunming University of Medicine -
Preferential Admission Policies for Ethnic Minority Students in Yunnan: Help Or Hindrance
356 International Journal of Learning, Teaching and Educational Research Vol. 19, No. 4, pp. 356-376, April 2020 https://doi.org/10.26803/ijlter.19.4.21 Preferential Admission Policies for Ethnic Minority Students in Yunnan: Help or Hindrance Dongyuan Deng Suranaree University of Technology, Thailand https://orcid.org/0000-0002-7003-8157 Sirinthorn Seepho Suranaree University of Technology, Thailand https://orcid.org/0000-0002-5048-5435 Andrew Lian Suranaree University of Technology, Thailand https://orcid.org/0000-0002-5812-3017 Abstract. This research project took Yunnan (YN), the most southwestern province of China and a frontier province with the largest number of ethnic minorities along with multi-ethnic languages and abundant ethnic cultures, as a specific case. It studied both the current situation of minority education and the necessity for Preferential Admission Policies (PAPs) in the particular stage of the national college entrance examination (NCEE) from a social perspective. Quantitative statistics was used to analyze data from the different education levels of the minority groups. Document analysis and in-depth interviews with four groups of participants (exclusive ethnic minority university students (EEMs), university teachers, administrators and provincial officials of Yunnan Province) were conducted to explore the rationality and feasibility of PAPs. The findings reveal that PAPs are indeed justified in Yunnan’s multi-ethnic social context, at the same time, geographical remoteness and regional gaps, socioeconomic determinants, and linguistic barriers contributed to the need for PAPs at present under the average level of minority education in Yunnan. Keywords: Yunnan; ethnic minority education; Preferential Admission Policies; entrance examination; social context 1. -
General Chairs' Message and Conference Program
2016 International Conference on Comp uter, Information and Telecommunication Systems July 6-8, 2016, Kunming, China Technical Sponsors: CITS 2016 is sponsored by Xidian University, China and Yunnan Minzu University, China. CITS 2016 General ChairsÊ Message Welcome to the 2016 International Conference on Computer, Information and Telecommunication Systems (CITS 2016). This year’s conference marks the fifth CITS, which is being held on annual basis. CITS 2016 offers a unique forum for researchers and practitioners from academia, industry, business, and government to share their expertise results and research findings in all areas of Computer, Information and Telecommunication Systems. This year’s conference includes an outstanding technical program, and four distinguished keynote speakers and two invited speakers. We have chosen the campus of the Yunnan Minzu University, Kunming, China as the site for our conference. The city of Kunming is famous in its great weather and historical significance. The site provides excellent meeting facilities and will be a comfortable setting for our conference. The CITS 2016 technical program consists of several parallel tracks and will last for three days. Each track consists of several sessions of top quality papers. The topics covered in the program include, among others, wireless networks, wireless sensor networks, computer networks and telecommunications, admission control in networking, cyber security, information security, cell networks, 4G and 5G systems, parallel and distributed computing, databases -
Yunnan Contemporary Higher Vocal Education
2019 International Conference on Social Science and Education (ICSSAE 2019) Yunnan Contemporary Higher Vocal Education Yu Chen1, a * 1 Music and Dance College of Qujing Normal University, Yunnan, China a [email protected] *Music and Dance College of Qujing Normal University, Yu Chen Keywords: Vocal Music; Higher Education; Yunnan; Contemporary Abstract: This article is based on the contemporary Chinese, from 1949 to the 21st century, and the development of higher vocal education in Yunnan in the past 70 years. It is divided into three parts: the founding of the People’ s Republic of China, the reform and opening up, and the beginning of the 21st century. Then it sorts out the historical track of vocal music education in colleges and universities, as well as the vocal music education experts who promote its development. Recovery and Development After the Founding of the People’s Republic of China At the end of 1949, Yunnan was peacefully liberated. And the Ministry of Culture and Education of the Southwest Military and Political Committee informed that the Kunming Normal University was renamed Kunming Normal College (renamed Yunnan Normal University on April 11, 1984). The party and the government paid great attention to the construction and development of Yunnan’ s cultural and educational undertakings. With the gradual recovery of the economy and the increasingly stable society, art education has become more and more concerned by the primary and secondary schools in the province. The Kunming Teachers College, which has been adhering to the spirit of the Southwest United University, has taken the lead in opening up art education. -
Cathelicidin-OA1, a Novel Antioxidant Peptide Identified from An
www.nature.com/scientificreports OPEN Cathelicidin-OA1, a novel antioxidant peptide identifed from an amphibian, accelerates skin Received: 9 October 2017 Accepted: 2 January 2018 wound healing Published: xx xx xxxx Xiaoqing Cao1, Ying Wang2, Chunyun Wu3, Xiaojie Li4, Zhe Fu3, Meifeng Yang3, Wenxin Bian3, Siyuan Wang2, Yongli Song3, Jing Tang4 & Xinwang Yang3 Cathelicidins play pivotal roles in host defense. The discovery of novel cathelicidins is important research; however, despite the identifcation of many cathelicidins in vertebrates, few have been reported in amphibians. Here we identifed a novel cathelicidin (named cathelicidin-OA1) from the skin of an amphibian species, Odorrana andersonii. Produced by posttranslational processing of a 198-residue prepropeptide, cathelicidin-OA1 presented an amino acid sequence of ‘IGRDPTWSHLAASCLKCIFDDLPKTHN′ and a molecular mass of 3038.5 Da. Functional analysis showed that, unlike other cathelicidins, cathelicidin-OA1 demonstrated no direct microbe-killing, acute toxicity and hemolytic activity, but did exhibit antioxidant activity. Importantly, cathelicidin-OA1 accelerated wound healing against human keratinocytes (HaCaT) and skin fbroblasts (HSF) in both time- and dose-dependent manners. Notably, cathelicidin-OA1 also showed wound-healing promotion in a mouse model with full-thickness skin wounds, accelerating re-epithelialization and granulation tissue formation by enhancing the recruitment of macrophages to the wound site, inducing HaCaT cell proliferation and HSF cell migration. This is the frst cathelicidin identifed from an amphibian that shows potent wound-healing activity. These results will help in the development of new types of wound-healing agents and in our understanding of the biological functions of cathelicidins. Cathelicidins, which belong to a group of cationic peptides with amphipathic properties, play critical roles in host defense1. -
Investigation of China's Yunnan Pharmaceutical Industry Derived from Two Ethnomedicines, Yi Medicine and Dai Medicine
Investigation of China’s Yunnan pharmaceutical industry derived from two ethnomedicines, Yi medicine and Dai medicine Zhiyong Li Kunming University of Science and Technology Caifeng Li Jiangxi University of Traditional Chinese Medicine Xiaobo Zhang China Academy of Chinese Medical Sciences Shihuan Tang China Academy of Chinese Medical Sciences Xiulan Huang Minzu University of China Hongjun Yang China Academy of Chinese Medical Sciences Xiuming Cui Kunming University of Science and Technology Luqi Huang ( [email protected] ) Research Keywords: Ethnomedicine; Dai patent medicine; Yi patent medicine; Ethnic Pharmaceutical Industry; Traditional knowledge Posted Date: January 22nd, 2020 DOI: https://doi.org/10.21203/rs.2.21598/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 1/21 Abstract Background: Yunnan Province is a multi-ethnic area located in the southwest of China, and she also is rich in Chinese matiera medica resources, known as the ‘kingdom of plants’. There is abundant of ethnomedicine resources in Yunnan province and many ethnic minorities inherit and retain numerous knowledge of traditional medicine. The biomedicine and big health industry have been the pillar industry of Yunnan since 2016, which is the important pharmaceutical industrial base for Dai Medicine and Yi Medicine in China, for example Yunnan Baiyao with “amazing ecacy” and originating from a Yi medical formula. Yi medicine and Dai medicine of Yunnan Province were investigated in this work focusing on the basic information of Dai patent medicine (DPM) and Yi patent medicine (YPM), including the clinical indications, herbal resources and their sources of traditional knowledge.