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CONFIDENTIAL.AISF Pre-Meeting & Annual Meeting 2020.Final

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CONFIDENTIAL.AISF Pre-Meeting & Annual Meeting 2020.Final A I S F ASSOCIAZIONE ITALIANA PER LO STUDIO DEL FEGATO Riconosciuta con D.M. del 7.5.1998, G.U. del 20.6.1998 Iscritta nell’Elenco di cui all'art. 1, comma 353, della Legge 23.12.2005 n. 266, D.P.C.M. 15.4.2011 Iscritta nell'Elenco di cui all'art. 14, comma 1, del D.L. 14.3.2005, n. 35, convertito nella Legge 14.5.2005 n. 80, D.P.C.M. 15.4.2011 53 rd AISF Annual Meeting Aula Magna, Università di Roma “Sapienza” - P.le A. Moro, 5 Rome, February 27 th -28 th , 2020 S CIENTIFIC P ROGRAMME Thursday, February 27 th 08.30-09.30 Selected Oral Communications F. Di Lorenzo, A. Giorgini, L. Sighinolfi, C. (Hepatitis B, C and delta clinical) Dentone, A. Lleo, B. Rossetti, I. Beretta, G. Chairpersons: Maurizia R. Brunetto (Pisa) Cariti, V. Ghisetti, P. Lampertico, G. Parruti, N. Mauro Viganò (Milan) Coppola, F. Baldanti, G.B. Gaeta, G. Raimondo, M. Puoti, M. Zazzi, M. Andreoni, M. Angelico, 08.30-08.45 Genetic and B-cell clonality markers in HCV- C.F. Perno, A. Craxì, F. Ceccherini-Silberstein related cryoglobulinemic vasculitis persisting on behalf of HCV Virology Italian Resistance after DAA therapy Network (Vironet C) - Rome, Pavia, Genoa, S. Marri, L. Gragnani, S. Lorini, V. Santarlasci, Milan, Messina, Naples, Palermo, Bari, Turin, U. Basile, M. Monti, L. Petraccia, C. Stasi, Pescara, Bergamo, Bologna, Modena, Sassari, L. Martini, F. Madia, M. Mudalal, P. Caini, Pisa, Castellana Grotte (BA), Latina, Foggia, N. Marello, L. Cosmi, F. Annunziato, A.L. Trento, Cagliari, Bari, Ferrara, Sanremo (IM), Zignego and the AISF Special Interest Group on Pieve Emanuele (MI), Siena, Monza (MB) “Systemic Manifestations from hepatitis viruses” - Florence, Rome 09.15-09.30 Comprehensive characterization of HBV in tumor and non-tumor liver tissues from 08.45-09.00 Procoagulant imbalance in patients with non- patients with HBV related-HCC cirrhotic Chronic hepatitis C (CHC) improves D. Giosa, F. Casuscelli di Tocco, G. Raffa, C. six months after eradication with direct- Musolino, D. Lombardo, C. Saitta, R. Aiese acting antiviral agents (DAAs) and likely Cigliano, W. Sanseverino, O. Romeo, G. correlates with liver fibrosis Navarra, G. Raimondo, T. Pollicino - Messina, G. Sigon, G. Pisano, R. D'ambrosio, M. Clerici, Barcelona (Spain) V. Chantarangkul, P. Lampertico, R. Lombardi, R. Sollazzi, F. Peyvandi, A. Tripodi, 09.30-10.00 State-of-the-Art Lecture A.L. Fracanzani - Milan Disease Modifying Agents in Advanced Chronic Liver Diseases 09.00-09.15 VIRONET-C real life experience of resistance- Paolo Caraceni (Bologna) guided retreatment in HCV infected patients Introduced by: Prof. Paolo Angeli (Padua) who previously failed a NS5A inhibitor- containing regimen 10.00 -11.00 General Assembly II V.C. Di Maio, M. Aragri, C. Masetti, S. 11.00- 11.30 Coffee break and Posters view Paolucci, B. Bruzzone, E. Degasperi, S. Tutors clinical: Ernesto Claar (Naples) - Marco Barbaliscia, T. Pollicino, C. Minichini, V. Di Pascoli (Padua) Calvaruso, M. Rendina, V. Cento, E. Teti, V. Tutors experimental: Rosaria Maria Pipitone Micheli, T. Allice, E. Polilli, V. Pace Palitti, S. (Palermo) - Chiara Raggi (Florence) Landonio, I. Lenci, S. Francioso, L. Donnarumma, L.A. Nicolini, A. Bertoli, M. 11.30-12.30 Selected Oral Communications Starace, C. Pasquazzi, A.P. Callegaro, F. (Autoimmune and Biliary diseases; Morisco, G. Cenderello, S. Marenco, R. miscellaneous) Gulminetti, S. Novati, A. Scuteri, P. Andreone, Chairpersons: Ana Lleo De Nalda (Rozzano) S. Galli, A. Ciancio, V. Sangiovanni, N. Cuomo, Antonio Moschetta (Bari) A. Raddi, W. Gennari, E. Boeri, G. Morsica, H. 11.30-11.45 Serum gamma-glutamyltransferase is a Hasson, V. Borghi, I. Maida, M. Brunetto, P. prognostic biomarker in primary biliary Colombatto, R. Cozzolongo, A. De Santis, M. cholangitis and improves risk stratification Lichtner, S. Babudieri, E. Biliotti, G. Taliani, T. based on alkaline phosphatase Santantonio, M. Di Stefano, C. Paternoster, R. A. Gerussi, D. Bernasconi, S.E. O'donnell, W.J. Ganga, M. Merli, G. Rizzardini, A. Pellicelli, V. Giannelli, E. Milano, C. Mastroianni, A. Licata, A I S F ASSOCIAZIONE ITALIANA PER LO STUDIO DEL FEGATO Riconosciuta con D.M. del 7.5.1998, G.U. del 20.6.1998 Iscritta nell’Elenco di cui all'art. 1, comma 353, della Legge 23.12.2005 n. 266, D.P.C.M. 15.4.2011 Iscritta nell'Elenco di cui all'art. 14, comma 1, del D.L. 14.3.2005, n. 35, convertito nella Legge 14.5.2005 n. 80, D.P.C.M. 15.4.2011 Lammers, H. Van Buuren, G. Hirschfield, H. Floreani Padua, Pisa, Genoa, Monza (MB), Janssen, C. Corpechot, A. Reig, A. Pares, P.M. Rome, Palermo, Naples Battezzati, M.G. Zuin, N. Cazzagon, A. Floreani, The weight of pre-existing cofactors for liver F. Nevens, N. Gatselis, G. Dalekos, M.J. Mayo, disease progression in patients who D. Thorburn, T. Bruns, A.L. Mason, V. Xavier, K. successfully eradicated HCV virus infection: Kowdley, P. Invernizzi, B. Hansen, M. Carbone - An interim analysis in the PITER cohort Monza (MB), Rotterdam (The Netherlands), L.A. Kondili, M.G. Quaranta, M. Monti, D.A. Toronto (Canada), Paris (France), Barcelona Amoruso, R. Filomia, E. Biliotti, A. Iannone, D. (Spain), Milan, Padua, Leuven Ieluzzi, B. Coco, F.P. Russo, I. Beretta, G. (Belgium), Larissa (Greece), Dallas (TX, USA), Parruti, P. Blanc, M. Vinci, V. Cossiga, E. London (United Kingdom), Jena Degasperi, L. Chemello, M. Massari, L. Badia, (Germany), Aachen (Germany), Edmonton M. Puoti, S.R. Bruno, M. De Siena, V. Panetta, (Canada), Ghent (Belgium), Seattle (WA, A. Aghemo - Rome, Florence, Messina, Bari, USA), Toronto (Canada) Verona, Pisa, Padua, Monza (MB), Pescara, 11.45-12.00 The metabolic plasticity of neoplastic Florence, Milan, Naples, Reggio Emilia, cholangiocytes: perspective for target Bologna, Foggia, Rozzano (MI) therapy of intrahepatic cholangiocarcinoma TM6SF2/PNPLA3/MBOAT7 loss-of-function M. Polidoro, L. Brunelli, C. Soldani, B. genetic variants impact on NAFLD Franceschini, G. Sestito, A. Aghemo, M. development and progression both in Donadon, R. Pastorelli, G. Torzilli, A. Lleo patients and in in vitro models Rozzano (MI), Milan, Pieve Emanuele (MI) M. Longo, M. Meroni, V. Erconi, A. Alisi, L. 12.00-12.15 Role of cellular senescence in the natural Miele, R. Rametta, A.L. Fracanzani, L.Valenti, P. history of primary sclerosing cholangitis Dongiovanni - Milan, Rome S. Sarcognato, N. Cazzagon, G. Corrà, S. De 14.15-15.15 Rare diseases Symposium Martin, V. Guzzardo, A. Floreani, F.P. Russo, Chairpersons: Ana Lleo De Nalda (Rozzano) M. Guido - Padua Luca Valenti (Milan) 12.15-12.30 Pre-existing liver disease and severity of DILI 14.15-14.30 Novel therapeutic approaches in cholestatic in an Italian cohort autoimmune disorders: evidence from clinical M.G. Minissale, V. Calvaruso, A. Liguori, L. studies Miele, M. Soresi, L. Giannitrapani, G. Marrone, Pietro Invernizzi (Milan) A. Gasbarrini, G. Montalto, A. Grieco, A. Craxì, 14.30-14.45 Impact of enzyme replacement/substrate A. Licata - Palermo, Rome reduction therapies on liver involvement in patients with lysosomal storage disorders 12.30-13.00 «Valerio Nobili» Young Investigator Lecture Fabio Nascimbeni (Modena) Cholestatic Liver Diseases 14.45-15.00 Whole exome sequencing for the diagnosis of Marco Carbone (Milan) rare genetic conditions in patients with Introduced by: Pietro Invernizzi (Milan) unexplained liver disease 13.00-14.15 Lunch break and Posters view Serena Pelusi (Milan) Tutors clinical: Ernesto Claar (Naples) - Marco 15.00-15.15 Discussion Di Pascoli (Padua) 15.15-15.45 State-of-the-Art Lecture Tutors experimental: Rosaria Maria Pipitone Liquid biopsy: next generation biomarkers for (Palermo) - Chiara Raggi (Florence) liver cancer 13.45-14.15 Selected Poster Guided Tour Jesus M. Banales (Navarra - Spain) Tutors: Fabio Marra (Florence) Introduced by: Domenico Alvaro (Rome) Luca Miele (Rome) 15.45-16.15 Difficult to treat: Infections in cirrhosis Perception of illness in Italian patients with Chairpersons: Raffaele Bruno (Pavia) Primary Biliary Cholangitis referred to tertiary Giovanni Battista Gaeta (Naples) care units 16.15-16.45 Coffee break and Posters view N. Cazzagon, M. Scaffidi, B. Coco, E.G. Tutors clinical: Ernesto Claar (Naples) - Marco Giannini, V. Cacciato, E. Bonaiuto, S. De Di Pascoli (Padua) Martin, P. Invernizzi, M. Carbone, D. Alvaro, Tutors experimental: Rosaria Maria Pipitone M.C. Bragazza, V. Calvaruso, F. Morisco, A. (Palermo) - Chiara Raggi (Florence) A I S F ASSOCIAZIONE ITALIANA PER LO STUDIO DEL FEGATO Riconosciuta con D.M. del 7.5.1998, G.U. del 20.6.1998 Iscritta nell’Elenco di cui all'art. 1, comma 353, della Legge 23.12.2005 n. 266, D.P.C.M. 15.4.2011 Iscritta nell'Elenco di cui all'art. 14, comma 1, del D.L. 14.3.2005, n. 35, convertito nella Legge 14.5.2005 n. 80, D.P.C.M. 15.4.2011 16.45-17.00 Presentation of the AISF prize for the 2 best 17.30-17.45 Noninvasive risk stratification in nonalcoholic Italian papers in 2019 fatty liver disease: a polygenic risk score Basic Science: Teresa Pollicino (Messina) C. Bianco, S. Pelusi, G. Baselli, I. Zanoni, A. Erica Villa (Modena) Taliento, P. Dongiovanni, R. Rametta, V. Clinical: Calogero Cammà (Palermo) Borroni, A. Federico, U. Vespasiani-Gentilucci, Agostino Colli (Lecco) R. D’Ambrosio, E. Bugianesi, S. Petta, L. Miele, H. Reeves, A. Fracanzani, G. Soardo, D. Prati, L. 17.00-18.00 Selected Oral Communications Valenti - Udine, Milan, Gallarate (VA), Naples, (NAFLD/ALD clinical and experimental) Rome, Turin, Palermo, Newcastle upon Tyne Chairpersons: Elisabetta Bugianesi (Turin) (UK) Carlo Saitta (Messina) 17.45-18.00 Interplay between metabolic derangement, 17.00-17.15 PCSK9 rs11591147 R46L loss-of-function hepatic fibrogenesis and macrophage variant protects against liver damage in activation in non-diabetic patients with non- individuals with non-alcoholic fatty liver alcoholic fatty liver disease S.
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