A History of Leprosy and Coercion in Hawai’I
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Evidence for Mycobacterium Leprae Drug Resistance in a Large Cohort of Leprous Neuropathy Patients from India
Am. J. Trop. Med. Hyg., 102(3), 2020, pp. 547–552 doi:10.4269/ajtmh.19-0390 Copyright © 2020 by The American Society of Tropical Medicine and Hygiene Evidence for Mycobacterium leprae Drug Resistance in a Large Cohort of Leprous Neuropathy Patients from India Niranjan Prakash Mahajan,1 Mallika Lavania,2 Itu Singh,2 Saraswati Nashi,1 Veeramani Preethish-Kumar,1 Seena Vengalil,1 Kiran Polavarapu,1 Chevula Pradeep-Chandra-Reddy,1 Muddasu Keerthipriya,1 Anita Mahadevan,3 Tagaduru Chickabasaviah Yasha,3 Bevinahalli Nanjegowda Nandeesh,3 Krishnamurthy Gnanakumar,3 Gareth J. Parry,4 Utpal Sengupta,2 and Atchayaram Nalini1* 1Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, India; 2Stanley Browne Research Laboratory, TLM Community Hospital, New Delhi, India; 3Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, India; 4Department of Neurology, St John’s Medical College, Bangalore, India Abstract. Resistance to anti-leprosy drugs is on the rise. Several studies have documented resistance to rifampicin, dapsone, and ofloxacin in patients with leprosy. We looked for point mutations within the folP1, rpoB, and gyrA gene regions of the Mycobacterium leprae genome predominantly in the neural form of leprosy. DNA samples from 77 nerve tissue samples were polymerase chain reaction (PCR)-amplified for MlepraeDNA and sequenced for drug resistance–determining regions of genes rpoB, folP1, and gyrA. The mean age at presentation and onset was 38.2 ±13.4 (range 14–71) years and 34.9 ± 12.6 years (range 10–63) years, respectively. The majority had borderline tuberculoid leprosy (53 [68.8%]). Mutations associated with resistance were identified in 6/77 (7.8%) specimens. -
A Descriptive Study from Patients' Perspective in Sri Lanka
Scientific Research Journal (SCIRJ), Volume V, Issue IX, September 2017 10 ISSN 2201-2796 Stigmatization in Leprosy: A descriptive study from patients’ perspective in Sri Lanka M.A.J.D. Mallawa Arachchi, A.G.D. Kumari Leprosy Hospital Hendala, Sri Lanka R. Wickramasinghe Dept. of Basic Sciences The Open University of Sri Lanka Nawala, Nugegoda [email protected] N.R. Kuruppu, A.V. Pramuditha Madhavi Dept. of Nursing The Open University of Sri Lanka Nawala, Nugegoda [email protected], [email protected] Abstract- The stigma of leprosy is a real phenomenon in many period from year 2000 to 2013. Six new leprosy patients are people’s lives that affects their physical, psychological, social and being detected in Sri Lanka daily [4]. economic well-being. The objective of the study is to investigate People with leprosy and related deformities suffer from the stigma in leprosy from patient’s perspective. Further this social stigma and discrimination leading to economic loss [5]. study help to determine how stigmatization affect the social life of Stigma is not a single phenomenon and can be define as “an patients with leprosy, how stigmatization affect the psychological aspect of patient’s life and identify the coping mechanisms attribute that is deeply discrediting, and the stigmatized employed by patients to manage the stigma. This study was individual is one who is not accepted and is not accorded the conducted in the central leprosy clinic in National Hospital in Sri respect and regard of his peers; one who is disqualified from Lanka. The data were collected from hundred and thirty two full social acceptance” [8]. -
Interrogating Leprosy 'Stigma'
Lepr Rev (2011) 82, 91–97 EDITORIAL Interrogating leprosy ‘stigma’: why qualitative insights are vital JAMES STAPLES Brunel University, Uxbridge, Middlesex UB8 3PH Accepted for publication 24 April 2011 I was initially in two minds about editing a special issue on ‘stigma’. The term, it seemed to me, was one too often applied uncritically to bodily conditions – especially in relation to leprosy – as a vague gloss for a qualitatively diverse range of negative social reactions and attitudes, as well as a description of how they might be experienced. As such, ‘stigma’ can become a lazy shortcut for the multiple ‘social aspects’ of leprosy, preventing deeper scrutiny of the complex and sometimes contradictory experiences that are characteristic of living with the disease. At the same time, however, devoting a special issue to the topic also offers a valuable opportunity to address precisely those issues: to interrogate how, if at all, ‘stigma’ might remain a conceptually useful notion through which to analyse the experience of those whose lives are touched by leprosy, whether as sufferers, family members or those working in the leprosy field. It also provides a chance to showcase alternative approaches to understanding attitudes towards the disease that go beyond the conventional, taken for granted wisdom which states, a) that leprosy is a uniformly stigmatised disease, and b) that education about its causes and treatments is necessarily the appropriate response to managing that stigma. A critical focus on stigma allows us to ask, for example, questions about the socio-cultural, historical, economic and political contexts in which stigma is produced. -
Historical Overview of Leprosy Control in Cuba
Review Article Historical Overview of Leprosy Control in Cuba Enrique Beldarraín-Chaple MD PhD ABSTRACT Program was established in 1962, implemented in 1963 and revised INTRODUCTION Leprosy, an infectious disease caused by Myco- fi ve times. In 1972, leper colonies were closed and treatment became bacterium leprae, affects the nervous system, skin, internal organs, ambulatory. In 1977, rifampicin was introduced. In 1988, the Program instituted controlled, decentralized, community-based multidrug treat- extremities and mucous membranes. Biological, social and environ- ment and established the criteria for considering a patient cured. In 2003, mental factors infl uence its occurrence and transmission. The fi rst it included actions aimed at early diagnosis and prophylactic treatment of effective treatments appeared in 1930 with the development of dap- contacts. Since 2008, it prioritizes actions directed toward the population sone, a sulfone. The main components of a control and elimination at risk, maintaining fi ve-year followup with dermatological and neurologi- strategy are early case detection and timely administration of multi- cal examination. Primary health care carries out diagnostic and treatment drug therapy. activities. The lowest leprosy incidence of 1.6 per 100,000 population was achieved in 2006. Since 2002, prevalence has remained steady at OBJECTIVES Review the history of leprosy control in Cuba, empha- 0.2 per 10,000 population. Leprosy ceased to be considered a public sizing particularly results of the National Leprosy Control Program, its health problem in Cuba as of 1993. In 1990–2015, 1.6% of new leprosy modifi cations and infl uence on leprosy control. patients were aged <15 years. -
Elisabeth Catherine Mentha Hill
The Roots of Persecution: a comparison of leprosy and madness in late medieval thought and society by Elisabeth Catherine Mentha Hill A thesis submitted in partial fulfillment of the requirements for the degree of Master of Arts in History Department of History and Classics University of Alberta © Elisabeth Catherine Mentha Hill, 2016 Abstract This thesis compares madness and leprosy in the late Middle Ages. The first two chapters explore the conceptualization of madness and leprosy, finding that both were similarly moralized and associated with sin and spiritual degeneration. The third chapter examines the leper and the mad person as social identities and finds that, although leprosy and madness, as concepts, were treated very similarly, lepers and the mad received nearly opposite social treatment. Lepers were collectively excluded and institutionalized, while the mad were assessed and treated individually, and remained within their family and community networks. The exclusionary and marginalizing treatment of lepers culminated, in 1321, in two outbreaks of persecutory violence in France and Aragon, and in lesser but more frequent expulsions through the fourteenth and fifteenth centuries. The mad were not subject to comparable, collective violence. In light of the similar moral and spiritual content of leprosy and madness as concepts, this comparison indicates that a morally condemned or stigmatized condition was not sufficient to generate persecution, or to produce a persecuted social identity. It was the structure of the concept leprosy that produced a collective social identity available to the persecuting apparatus of late medieval society, while the fluid concept of madness produced the more individual identity of the mad person, which was less susceptible to the collective actions of persecution. -
550 Leprosy in China: a History. by Angela Ki-Che Leung. New York
550 Book Reviews / T’oung Pao 96 (2011) 543-585 Leprosy in China: A History. By Angela Ki-che Leung. New York: Columbia Uni- versity Press, 2009. 373 pp. Index, bibliography, ill. Angela Leung’s new book adds a very important case study that historicizes the recent “modernist” works on the history of public health in China by Ruth Rogaski,1 Carol Benedict,2 and Kerrie Macpherson.3 Unlike the above three works, which all focus on “modernity” and have rightly been well-received, Leung presents a highly original, postcolonial history of leprosy in China, which was known in antiquity as li/lai, wind-induced skin ailments, or mafeng, “numb skin.” ese symptoms were subsequently combined during the Song dynasty into a single etiology of skin ailments , i.e., dafeng/lai. Leung’s pioneering account successfully provincializes the European narrative of leprosy and public health by presenting: 1) the longer historical memory of “leprosy” in China since antiquity; 2) the important public health changes that occurred during the Song dynasty (960-1280); and 3) how the skin illnesses we call leprosy were reconceptualized during the Ming and Qing dynasties. Leung then concludes her manuscript with two fi nal chapters that successfully parallel but revise the accounts in Rogaski, Benedict, and Macpherson. Leung describes Chinese political eff orts since the nineteenth century to develop not simply a “modern” and “Western” medical regime but a “hybrid,” Sino-Western public health system to deal with the disease. e book reveals overall the centrality of China in the history of the leprosy, and it shows how leprosy played out as a global threat, which provides lessons for dealing with AIDS, SARS, and bird viruses today. -
Disability-Related Stigma and Discrimination in Sub-Saharan Africa and South Asia: a Systematic Literature Review May 2021
Disability-related stigma and discrimination in sub-Saharan Africa and south Asia: a systematic literature review May 2021 Report authors: Bhavisha Virendrakumar Cathy Stephen Emma Jolley Elena Schmidt Study contributors: Vladimir Pente Elizabeth Clery Acknowledgement: We would like to thank Irish Aid for the funding provided for this review. Many thanks to the systematic review Steering Committee, who provided valuable comments on the protocol and draft report. Recommended citation: Sightsavers. Disability-related stigma and discrimination in sub-Saharan Africa and South Asia: a systematic literature review. Haywards Heath, UK: Sightsavers, 2021. 2 Disability-related stigma and discrimination in sub-Saharan Africa and South Asia: a systematic literature review | May 2021 Contents Executive summary .............................................................................................................. 6 Introduction ........................................................................................................................ 6 Methods ............................................................................................................................. 7 Results ............................................................................................................................... 7 Characteristics of included studies ................................................................................. 7 Factors leading to stigma and discrimination ................................................................ -
Qualitative Exploration of Experiences and Consequences of Health-Related Stigma Among Indonesians with HIV, Leprosy, Schizophrenia and Diabetes
Rai et al. Kesmas: National Public Health Journal. 2020; 15 (1): 7-16 Kesmas: National Public Health Journal DOI:10.21109/kesmas.v15i1.3306 Qualitative Exploration of Experiences and Consequences of Health-related Stigma among Indonesians with HIV, Leprosy, Schizophrenia and Diabetes Sarju Sing Rai1,2, Irwanto3*, Ruth M H Peters1,... 1Athena Institute, Faculty of Science, Vrije University Amsterdam, Amsterdam, The Netherlands 2Barcelona Institute for Global Health (ISGlobal), University of Barcelona, Barcelona, Spain 3Department of Psychology, Atma Jaya Catholic University, Jakarta, Indonesia Abstract Health-related stigma causes a negative impact on the lives of affected people and undermines the effectiveness of public health programs. This study aimed to explore experiences and consequences of stigma among people affected by four health conditions relevant in Indonesia– HIV (Human Immunodeficiency Virus), leprosy, schizophrenia and diabetes. In this qualitative study 40 people affected by the four health conditions in Jakarta and West Java, Indonesia–, were interviewed between March and June 2018. Data were analyzed thematically by following an integrative inductive-deductive approach. The experiences and consequences of people with stigma were similar, but such experience were more severe among people affected by HIV, leprosy, and schizophrenia. Those with diabetes either experienced no or less severe stigma. The participants revealed that they experienced enacted stigma in healthcare, employment, and social interactions in the structural -
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Journal of Public Health in Africa 2011 ; volume 2:e10 Social stigma as an epidemio- lack of self-esteem, tribal stigma and complete rejection by society. From the 480 structured Correspondence: Dr. Dickson S. Nsagha, logical determinant for leprosy questionnaires administered, there were over- Department of Public Health and Hygiene, elimination in Cameroon all positive attitudes to lepers among the study Medicine Programme, Faculty of Health Sciences, population and within the divisions (P=0.0). University of Buea, PO Box 63, Buea, Cameroon. Dickson S. Nsagha,1,2 The proportion of participants that felt sympa- Tel. +237. 77499429.E-mail: [email protected] [email protected] Anne-Cécile Z.K. Bissek,3 thetic with deformed lepers was 78.1% [95% 4 confidence interval (CI): 74.4-81.8%] from a Sarah M. Nsagha, Key words: leprosy, social stigma, attitudes, elim- Anna L. Njunda,5 total of 480. Three hundred and ninety nine ination, Cameroon. Jules C.N. Assob,6 (83.1%) respondents indicated that they could Earnest N. Tabah,7 share a meal or drink at the same table with a Acknowledgements: the authors are grateful to Elijah A. Bamgboye,2 deformed leper (95% CI: 79.7-86.5%). Four Mr. Nsagha BN, Mr. Nsagha IG and Late Papa hundred and three (83.9%) participants indi- James Nsagha, who sponsored this study. The Alain Bankole O.O. Oyediran,2 cated that they could have a handshake and authors also thank Mr. Agyngi CT & Mr. Ideng DA Peter F. Nde,1 embrace a deformed leper (95% CI: 80.7- of the Benakuma Health Center; Mr. -
An Exploratory Study Towards Disclosure Of
UNIVERSITY OF KWAZULU-NATAL AN EXPLORATORY STUDY TOWARDS DISCLOSURE OF STATUS AND REDUCTION OF STIGMA FOR PEOPLE LIVING WITH HIV/AIDS IN A LOW INCOME COMMUNITY: THE DEVELOPMENT OF A COMMUNITY-BASED FRAMEWORK AYISHA RAZAK AN EXPLORATORY STUDY TOWARDS DISCLOSURE OF STATUS AND REDUCTION OF STIGMA FOR PEOPLE LIVING WITH HIV/AIDS IN A LOW INCOME COMMUNITY: THE DEVELOPMENT OF A COMMUNITY-BASED FRAMEWORK BY AYISHA RAZAK A THESIS SUBMITTED TO THE FACULTY OF HEALTH SCIENCES UNIVERSITY OF KWAZULU-NATAL (DURBAN) SOUTH AFRICA In fulfillment of the degree of DOCTOR OF PHILOSOPHY (NURSING) Supervised by PROFESSOR B. R. BHENGU AND PROFESSOR P. BRYSIEWICZ DECEMBER 2010 i DEDICATION This thesis is dedicated to my children, Shabnam, Gulshan and Mohammed Ishruth, my son-in-law, Ahmed Mahomed Cassoo and my adorable grandson, Talha for their love, encouragement and support through this journey. ii ACKNOWLEDGEMENTS I am most grateful to the Almighty Allah for giving me the inner strength, stamina and perseverance to complete this study. My sincere gratitude and appreciation goes to the following people and organizations: Professor Adejumo, my supervisor in the early stages of this project. Thank you for your guidance and supervision. Professor Busi Bhengu, my supervisor for her guidance, patience and encouragement throughout the study. You have been a very good role model to me. Professor Petra Brysiewicz, my co-supervisor for her guidance, patience, encouragement and especially the “hello there” that just boosted my spirits to continue and finally complete my study. PLWHA, who participated in the study? It was the most enriching experience in my life listening to your stories, sometimes very threatening but challenging. -
Stigma and Health Care Among the Men with the Experience Sex with Men in Dhaka City
Stigma and health care among the Men with the experience Sex with men in Dhaka city The Advanced Research Thesis is submitted to the Department of Sociology, University of Dhaka in partial fulfillment of the Degree of Master of Social Sciences By Exam Roll: 3988 Session 2012-2013 Registration No: Ha-5112 MSS 2nd semester December 2014 Abstract Health care is one of the basic needs of the human being. Right to health care is recognized globally by the declaration of various international agreements .The right to health is the economic, social and cultural right to a universal minimum standard of health to which all individuals are entitled. The concept of a right to health has been enumerated in international agreements which include the Universal Declaration of Human Rights, International Covenant on Economic, Social and Cultural Rights and the Convention on the Rights of Persons with Disabilities. An alternative way to conceptualize one facet of the right to health is a “human right to health care.” So Men having sex with men (MSM) also deserve the right to health. But stigma plays a significant role as barrier of getting health care services. Bangladesh is a religiously rigid country, so MSM behavior in this country is publicly prohibited religiously, socially and culturally. That‟s why health care services are a crucial issue for the Men having sex with men (MSM). Here health care for the MSM is related to stigma. There are so many studies or research work internationally and nationally on HIV/AIDS related health care services and MSM. But stigma related health care service is ignored in these studies. -
Review of Stigma Research
ABSTRACT EXAMINING CAUSAL BELIEFS AND STIGMATIZING ATTITUDES TOWARD PERSONS DIAGNOSED WITH SEVERE MENTAL ILLNESS by E. K. Reese Persons diagnosed with severe mental illness are frequently stigmatized as dangerous and unpredictable. Historically, these attitudes have perpetuated years of cruel, inhumane treatment of persons diagnosed with severe mental illness. Stigma research continues to show a link between a belief in the biological/genetic origins of mental illness and higher levels of stigmatization and prejudice. Despite this fact, the most visible anti-stigma programs portray mental illness as “an illness like any other,” such as diabetes or cancer, with the belief that a reduction in blame will result in a reduction in stigma. Several explanations have been provided about why the biological explanation of mental illness is not correlated with decreases in stigma. However, no study thus far has gone beyond conjecture. In the present study, I used a qualitative approach to seek out the underlying attitudes that may contribute to increased stigmatization with a biogenetic conceptualization of mental illness. EXAMINING CAUSAL BELIEFS AND STIGMATIZING ATTITUDES TOWARD PERSONS DIAGNOSED WITH SEVERE MENTAL ILLNESS A Thesis Submitted to the faculty of Miami University in partial fulfillment of the requirements for the degree of Master of Arts Department of Psychology by Emily K. Reese Miami University Oxford, Ohio 2010 Advisor _______________________ Larry M. Leitner, Ph.D. Reader _______________________ Elise Radina, Ph.D. Reader _______________________