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List of "Designated Substances" in Japan (As of August 25, 2021)

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List of "Designated Substances" in Japan (as of October 8, 2021) Drug category, "Designated Substances (*)" was newly established in 2007 to control new psychoactive substances (NPS). Their manufacture, import, sale, display, possession, use etc. are generally prohibited except for scietific purposes. A total 2392 substances including 2 plants (Salvia Divinorum and Mitragina Speciosa (Kratom)) are currently controlled as "Designated Substances". (Substances basis 299, Generic scheduling 2098) 69 substances, such as JWH-018, mephedrone, MDPV etc. have been already reclassified to be "Narcotics". (*)They are controlled by "The Act on Securing Quality, Efficacy and Safety of Products Including Pharmaceuticals and Medical Devices". No. Name Other Name Chemical Structure Date of Enforcement 1 Isobutyl nitrite April 1, 2007 ONO 2 Isopropyl nitrite April 1, 2007 ONO 3 Isopentyl nitrite Isoamyl nitrite April 1, 2007 ONO 4 tert-Butyl nitrite April 1, 2007 ONO ONO 5 Cyclohexyl nitrite April 1, 2007 6 Butyl nitrite April 1, 2007 ONO N O 4-Acetyl-N,N-diethyl-7-methyl-4,6,6a,7,8,9- 7 ALD-52 N February 28, 2020 hexahydroindolo[4,3-fg]quinoline-9-carboxamide N O O O 8 4-Acetoxy-N -isopropyl-N- metyltryptamine 4-AcO-MIPT N April 4, 2015 N H O O 9 4-Acetoxy-N -ethyl-N -methyltryptamine 4-AcO-MET N August 8, 2015 N H O O 10 4-Acetoxy-N ,N -diallyltryptamine 4-AcO-DALT N August 8, 2015 N H O O 11 4-Acetoxy-N ,N -diisopropyltryptamine 4-AcO-DIPT N April 1, 2007 N H O O 12 4-Acetoxy-N,N -diethyltryptamine 4-AcO-DET N August 8, 2015 N H O O 13 4-Acetoxy-N,N -dimethyltryptamine 4-AcO-DMT N August 8, 2015 N H O N H N N -(1-Adamantyl)-1-(5-chloropentyl)-1H -indazole-3- APINACA N -(5- N 14 April 18, 2016 carboxamide chloropentyl) analog Cl 1 No. Name Other Name Chemical Structure Date of Enforcement N -(1-Adamantyl)-1-[(tetrahydro-2H -pyran-4-yl)methyl]-1H - Adamantyl-THPINACA 15 March 6, 2017 indazole-3-carboxamide ATHPINACA O Adamantyl-THPINACA 2- N N -(2-Adamantyl)-1-[(tetrahydro-2H -pyran-4-yl)methyl]-1H - adamantyl isomer H N 16 indazole-3-carboxamide ATHPINACA 2-adamantyl N March 6, 2017 isomer O O N H N -(1-Adamantyl)-1-(4-fluorobenzyl)-1H -indazole-3- N 17 carboxamide FUB-APINACA N January 5, 2015 F O N H APICA N-(5-fluoropentyl) N -(1-Adamantyl)-1-(5-fluoropentyl)-1H -indole-3- N 18 derivative May 30, 2013 carboxamide STS-135 F O N H N APINACA N 19 N -(1-Adamantyl)-1-pentyl-1H -indazole-3-carboxamide July 1, 2012 AKB48 O O N 20 1-Adamantyl 1-pentyl-1H -indazole-3-carboxylate ACBL(N)-018 N December 29, 2017 O N 21 1-Adamantyl(1-pentyl-1H -indol-3-yl)methanone AB-001 May 30, 2013 O N H APICA N 22 N -(1-Adamantyl)-1-pentyl-1H -indole-3-carboxamide July 1, 2012 2NE1 O 1-Adamantyl{1-[(1-methylpiperidin-2-yl)methyl]-1H -indol-3- 23 AM1248 N May 30, 2013 yl｝methanone N O H2N N -(1-Amino-1-oxo-3-phenylpropan-2-yl)-1- APP-CHMINACA N 24 H September 3, 2016 (cyclohexylmethyl)-1H -indazole-3-carboxamide PX-3 O N N 2 No. Name Other Name Chemical Structure Date of Enforcement O H2N N N -(1-Amino-1-oxo-3-phenylpropan-2-yl)-1-(4-fluorobenzyl)- H 25 FU-PX-2 August 29, 2015 1H -indazole-3-carboxamide O N N F O H2N N H N -(1-Amino-1-oxo-3-phenylpropan-2-yl)-1-(5-fluoropentyl)- O N 26 PX-2 November 28, 2014 1H -indazole-3-carboxamide N F O H2N N N -(1-Amino-1-oxo-3-phenylpropan-2-yl)-1-(5-fluoropentyl)- H O 27 1H -indole-3-carboxamide PX-1 N November 28, 2014 F O H2N N N -(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1- ADB-CHMICA、 H 28 O February 19, 2019 (cyclohexylmethyl)-1H -indole-3-carboxamide MAB-CHMICA N N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-butyl-1H- 29 ADB-BUTINACA March 15,2021 indazole-3-carboxamide O H2N N H N -(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5- O N 30 fluoropentyl)-1H -indazole-3-carboxamide 5F-ADB-PINACA N November 28, 2014 F O H2N N H N -(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5- O 31 fluoropentyl)-1H -indole-3-carboxamide 5-fluoro-ADBICA N February 9, 2015 F O H2N N N -(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H - H O N 32 indazole-3-carboxamide ADB-PINACA N July 11, 2014 O H2N N H O N N -(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H - N 33 ADBICA May 30, 2013 indole-3-carboxamide 3 No. Name Other Name Chemical Structure Date of Enforcement O O NH 2 34 2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanone bk-2C-B April 4, 2015 Br O O H2N N H O N N -(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-chloropentyl)- N 35 5Cl-AB-PINACA November 8, 2014 1H -indazole-3-carboxamide Cl O H2N N N -(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(2-fluorobenzyl)- H AB-FUBINACA 2- O N 36 1H -indazole-3-carboxamide N December 5, 2015 fluorobenzyl isomer F O H2N N H N -(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)- O N N 37 1H -indazole-3-carboxamide 5‐Fluoro‐AB‐PINACA July 11, 2014 F O H2N N H O N -(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)- N 38 5-Fluoro-ABICA August 25, 2014 1H -indole-3-carboxamide F O NH 2 39 2-(4-Allyloxy-3,5-dimethoxyphenyl)ethanamine Allylescaline April 4, 2015 O O N O 7-Allyl-N,N-diethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg] 40 quinoline-9-carboxamide AL-LAD February 28, 2020 N HN O NH2 41 1-(4-Isopropylsulfanyl- 2,5-dimethoxyphenyl)propan-2-amine ALEPH-4 May 14, 2011 S O N 42 N -Isopropyl-N -methyltryptamine MIPT April 1, 2007 N H O N 43 N -Isopropyl-5-methoxy-N -methyltryptamine 5-MeO-MIPT April 1, 2007 N H 44 Nitrous oxide SIVAGUS N2O February 28, 2016 45 Indan-2-amine 2-AI January 11, 2008 NH2 O α-PBP indane analog N 46 1-(Indan-5-yl)-2-(pyrrolidin-1-yl)butan-1-one February 9, 2015 5-PPDI 4 No. Name Other Name Chemical Structure Date of Enforcement O N α-PHP indane analog 47 1-(Indan-5-yl)-2-(pyrrolidin-1-yl)hexan-1-one February 27, 2015 5-BPDI (1H -Indol-3-yl)(2,2,3,3-tetramethylcycropropan-1- 48 DP-UR-144 September 29, 2014 yl)methanone NH2 5-API 49 1-(1H -Indol-5-yl)propan-2-amine January 16, 2013 5-IT N H O H N 50 2-(Ethylamino)-1-(indan-5-yl)butan-1-one bk-IBP February 9, 2015 O H N 51 2-(Ethylamino)-1-(indan-5-yl)pentan-1-one bk-IVP February 9, 2015 52 3-[1-(Ethylamino)cyclohexyl]phenol 3-HO-PCE HO December 17, 2019 HN 53 2-(Ethylamino)-2-(thiophen-2-yl)cyclohexanone Tiletamine March 6, 2017 Deschloro-N-ethyl- ketamine 54 2-(Ethylamino)-2-phenylcyclohexanone Eticyclidone September 1, 2018 O-PCE 2-Oxo-PCE O N 55 N -Ethyl-N -isopropyl-5-methoxytryptamine 5-MeO-EIPT January 16, 2009 N H H N Ephenidine 56 N -Ethyl-1,2-diphenylethylamine EPE November 11, 2016 NEDPA O NH2 57 2-(4-Ethyl-2,5-dimethoxyphenyl)ethanamine 2C-E April 1, 2007 O O H 2-(4-Ethyl-2,5-dimethoxyphenyl)-N -(2-methoxybenzyl) N 58 ethanamine 25E-NBOMe June 1, 2015 O O 59 ２－［（４－Ethyl－２，５－dimethoxyphenethylamino）methyl］phenol 25E-NBOH December 19, 2018 O NH2 60 1-(4-Ethylsulfanyl-2,5-dimethoxyphenyl)propan-2-amine ALEPH-2 January 16, 2009 S O 5 No. Name Other Name Chemical Structure Date of Enforcement HO N 61 N -Ethyl-4-hydroxy-N -methyltryptamine 4-OH-MET April 4, 2015 N H H 62 1-（4-Ethylphenyl）-N -(2-methoxybenzyl)propan-2-amine 4-EA-NBOMe N December 29, 2017 O 63 Ethyl 2-(4-fluorophenyl)-2-(piperidin-2-yl)acetate 4-Fluoroethylphenidate March 15,2021 H N 2-FEA 64 N -Ethyl-1-（2-fluorophenyl）propan-2-amine February 19, 2019 2-fluoroethamphetamine F 3-FEA 65 N- Ethyl-1-（3-fluorophenyl）propan-2-amine November 24, 2018 3-fluoroethamphetamine 4-FEA 66 N -Ethyl-1-（4-fluorophenyl）propan-2-amine November 24, 2018 4-fluoroethamphetamine 3F-Phenetrazine 67 3-Ethyl-2-(3-fluorophenyl)morpholine September 8, 2017 3-FPE O O N H Ethyl 2-[1-(4-fluorobenzyl)-1H -indazole-3-carboxamido]-3- EMB-FUBINACA O N 68 September 3, 2016 methylbutanoate FUB-AEB N F O O N H O N Ethyl 2-[1-(5-fluoropentyl)-1H-indazole-3-carboxamido]-3,3- N 69 5F-EDMB-PINACA January 22, 2021 dimethylbutanoate F O O N H Ethyl 2-[1-(5-fluoropentyl)-1H -indazole-3-carboxamido]- O N 70 3-methylbutanoate 5F-AEB N July 2, 2016 F O O N H O Ethyl 2-[1-(5-fluoropentyl)-1H-indole-3-carboxamido]-3- N 71 5F-EMB-PICA, EMB-2201 August 25, 2021 methylbutanoate F 6 No.
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  • Virginia Acts of Assembly -- 2021 Special Session I

    Virginia Acts of Assembly -- 2021 Special Session I

    VIRGINIA ACTS OF ASSEMBLY -- 2021 SPECIAL SESSION I CHAPTER 110 An Act to amend and reenact §§ 3.2-4112, 3.2-4113, 3.2-4114.2, 3.2-4115, 3.2-4116, 3.2-4118, 3.2-4119, 18.2-247, 18.2-251.1:3, 54.1-3401, and 54.1-3446 of the Code of Virginia, relating to industrial hemp; emergency. [H 2078] Approved March 12, 2021 Be it enacted by the General Assembly of Virginia: 1. That §§ 3.2-4112, 3.2-4113, 3.2-4114.2, 3.2-4115, 3.2-4116, 3.2-4118, 3.2-4119, 18.2-247, 18.2-251.1:3, 54.1-3401, and 54.1-3446 of the Code of Virginia are amended and reenacted as follows: § 3.2-4112. Definitions. As used in this chapter, unless the context requires a different meaning: "Cannabis sativa product" means a product made from any part of the plant Cannabis sativa, including seeds thereof and any derivative, extract, cannabinoid, isomer, acid, salt, or salt of an isomer, whether growing or not, with a concentration of tetrahydrocannabinol that is greater than that allowed by federal law. "Deal" means to buy temporarily possess industrial hemp grown in compliance with state or federal law and to sell such industrial hemp to a person who that (i) processes industrial hemp in compliance with state or federal law or has not been processed and (ii) sells industrial hemp to a person who processes industrial hemp in compliance with state or federal law was not grown and will not be processed by the person temporarily possessing it.
  • Synthetic Cannabinoids (60 Substances) A) Classical Cannabinoid

    Synthetic Cannabinoids (60 Substances) A) Classical Cannabinoid

    Synthetic cannabinoids (60 substances) a) Classical cannabinoid OH H OH H O Common name Chemical name CAS number Molecular Formula HU-210 3-(1,1’-dimethylheptyl)-6aR,7,10,10aR-tetrahydro-1- Synonym: 112830-95-2 C H O hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanol 25 38 3 11-Hydroxy-Δ-8-THC-DMH b) Nonclassical cannabinoids OH OH R2 R3 R4 R1 CAS Molecular Common name Chemical name R1 R2 R3 R4 number Formula rel-2[(1 S,3 R)-3- hydroxycyclohexyl]- 5- (2- methyloctan- 2- yl) CP-47,497 70434-82-1 C H O CH H H H phenol 21 34 2 3 rel-2[(1 S,3 R)-3- hydroxycyclohexyl]- 5- (2- methylheptan- 2- yl) CP-47,497-C6 - C H O H H H H phenol 20 32 2 CP-47,497-C8 rel-2- [(1 S,3 R)-3- hydroxycyclohexyl]- 5- (2- methylnonan- 2- yl) 70434-92-3 C H O C H H H H Synonym: Cannabicyclohexanol phenol 22 36 2 2 5 CAS Molecular Common name Chemical name R1 R2 R3 R4 number Formula rel-2[(1 S,3 R)-3- hydroxycyclohexyl]- 5- (2- methyldecan- 2- yl) CP-47,497-C9 - C H O C H H H H phenol 23 38 2 3 7 rel-2- ((1 R,2 R,5 R)-5- hydroxy- 2- (3- hydroxypropyl)cyclohexyl)- 3-hydroxy CP-55,940 83003-12-7 C H O CH H H 5-(2- methyloctan- 2- yl)phenol 24 40 3 3 propyl rel-2- [(1 S,3 R)-3- hydroxy-5,5-dimethylcyclohexyl]- 5- (2- Dimethyl CP-47,497-C8 - C H O C H CH CH H methylnonan-2- yl)phenol 24 40 2 2 5 3 3 c) Aminoalkylindoles i) Naphthoylindoles 1' R R3' R2' O N CAS Molecular Common name Chemical name R1’ R2’ R3’ number Formula [1-[(1- methyl- 2- piperidinyl)methyl]- 1 H-indol- 3- yl]- 1- 1-methyl-2- AM-1220 137642-54-7 C H N O H H naphthalenyl-methanone 26 26 2 piperidinyl
  • Article 22 Regulation for Restriction of Synthetic Drugs

    Article 22 Regulation for Restriction of Synthetic Drugs

    ARTICLE 22 REGULATION FOR RESTRICTION OF SYNTHETIC DRUGS SECTION 22.1 AUTHORITY This regulation is promulgated under the authority granted to the Needham Board of Health under Massachusetts General Laws Chapter 111, Section 31 which states that “boards of health may make reasonable health regulations”. SECTION 22.2 PURPOSE The Needham Board of Health has found that synthetic marijuana, consisting of plant or other material treated with various chemicals or other synthetic substances not approved for human consumption, may be marketed and sold as herbal incense in the greater Boston area, although they are being used in the same manner and for the same purposes as scheduled drugs. In addition, the use of these products has become particularly popular among teens and young adults. Based on information and reports from hospitals, emergency room doctors, and police agencies, individuals who use these products experience dangerous side effects including convulsions, hallucinations, and dangerously elevated heart rates. This is evidence that synthetic marijuana products are harmful if inhaled or consumed, and present a significant public health danger. These synthetic compounds and others have a high potential for abuse and lack of any accepted medical use, these dangerous products, while not approved for human consumption, are marketed and sold in a form that allows for such consumption, putting at risk the individuals who come into contact with them. Therefore, the Needham Board of Health adopts this regulation for the purpose and with the intent to protect the public health and safety of the Town of Needham and its residents from the threat posed by the availability and use of synthetic marijuana, synthetic stimulants, synthetic hallucinogens, and other dangerous products by prohibiting persons from trafficking in, possessing, and using them within the town.