FY 2017 Annual Report July 1, 2016 – June 30, 2017
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Huda Y. Zoghbi, MD, Howard Hughes Medical Institute, Jan and Dan Duncan Neurological Research Institute at Texas Children’S Hospital and Baylor College of Medicine
Investigator Spotlight: Huda Y. Zoghbi, MD, Howard Hughes Medical Institute, Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital and Baylor College of Medicine It is hard to believe that the 7th World Rett Syndrome Congress has come and gone with great success! Now with summer upon us, IRSF continues to move the spotlight to the committed scientists who have made the World Congress an impressive, high quality meeting with outstanding presentations and discussions. This month we are honored to focus on Dr. Huda Zoghbi who had co-chaired the Basic Research Symposium at the World Congress along with Dr. Gail Mandel. Together, they had produced an exciting lineup of speakers who were encouraged to present new, unpublished data in an effort to foster new ideas that will help chart the course for Rett syndrome research. Dr. Zoghbi is a Howard Hughes Medical Institute (HHMI) Investigator, the Director of the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, and Professor of the Baylor College of Medicine in Houston, TX. She received her medical degree from Meharry Medical College and completed residency training in pediatrics and neurology at Baylor College of Medicine where she encountered her first Rett syndrome patient in 1983. Dr. Zoghbi was inspired to receive additional research training in the area molecular genetics and upon completion she joined the faculty of Baylor College of Medicine. In 1999, Dr. Zoghbi and collaborators including research fellow Ruthie Amir made a major breakthrough for Rett syndrome. They had discovered that mutations in MECP2, the gene encoding methyl-CpG-binding protein 2, causes Rett syndrome. -
UC San Diego UC San Diego Electronic Theses and Dissertations
UC San Diego UC San Diego Electronic Theses and Dissertations Title Spinocerebellar Ataxia Type 7 is Characterized by Defects in Mitochondrial and Metabolic Function Permalink https://escholarship.org/uc/item/02b7m809 Author Ward, Jacqueline Marie Publication Date 2016 Supplemental Material https://escholarship.org/uc/item/02b7m809#supplemental Peer reviewed|Thesis/dissertation eScholarship.org Powered by the California Digital Library University of California UNIVERSITY OF CALIFORNIA, SAN DIEGO Spinocerebellar Ataxia Type 7 is Characterized by Defects in Mitochondrial and Metabolic Function A dissertation submitted in partial satisfaction of the requirements for the degree Doctor of Philosophy in Biomedical Sciences by Jacqueline Marie Ward Committee in charge: Professor Albert La Spada, Chair Professor Eric Bennett Professor Lawrence Goldstein Professor Alysson Muotri Professor Miles Wilkinson 2016 Copyright Jacqueline Marie Ward, 2016 All rights reserved The Dissertation of Jacqueline Marie Ward is approved, and it is acceptable in quality and form for publication on microfilm and electronically: Chair University of California, San Diego 2016 iii DEDICATION This work is dedicated to my grandfather, Dr. Wayne Ward, the kindest person I’ve ever known. His memory inspires me to be a better person daily. iv TABLE OF CONTENTS SIGNATURE PAGE .......................................................................................... iii DEDICATION .................................................................................................. -
Program Book
PARKINSON’SDISEASE2014 ADVANCING RESEARCH, IMPROVING LIVES PROGRAM MATERIALS Sponsored by: January 6 – 7, 2014 Natcher Conference Center National Institutes of Health Bethesda, MD About our cover: The program cover image is a stylized version of the Parkinson’s Disease Motor-Related Pattern (PDRP), an abnormal pattern of regional brain function observed in MRI studies which shows increased metabolism indicated by red in some brain regions (pallidothalamic, pontine, and motor cortical areas), and decreased metabolism indicated by blue in others (associated lateral premotor and posterior parietal areas). Original image used with permission of David Eidelberg, M.D. For further information see: Hirano et al., Journal of Neuroscience 28 (16): 4201-4209. Welcome Message from Dr. Story C. Landis Welcome to the National Institute of Neurological Disorders and Stroke (NINDS) conference, “Parkinson’s Disease 2014: Advancing Research, Improving Lives.” Remarkable new discoveries and technological advances are rapidly changing the way we study the biological mechanisms of Parkinson’s disease, identify paths to improved treatments, and design effective clinical trials. Elucidating mechanisms and developing and testing effective interventions require a diverse set of approaches and perspectives. The NINDS has organized this conference with the primary goal of seeking consensus on, and prioritizing, research recommendations spanning clinical, translational, and basic Parkinson’s disease research that we support. We have assembled a stellar and dedicated group of session chairs and panelists who have worked collaboratively to identify emerging research opportunities in Parkinson’s research. While we have divided our working groups into three main research areas, we expect each will inform the others over the course of the next two days, and we look forward to both complementary and unique perspectives. -
Huda Zoghbi: Taking Genetic Inquiry to the Next Level
Spectrum | Autism Research News https://www.spectrumnews.org NEWS, PROFILES Huda Zoghbi: Taking genetic inquiry to the next level BY RACHEL ZAMZOW 25 JUNE 2021 Listen to this story: Most mornings, Huda Zoghbi, 67, climbs a glass-encased, curling staircase to reach her lab on the top and 13th floor of the Jan and Dan Duncan Neurological Research Institute in Houston, Texas. The twisting glass tower, which she designed with a team of architects, echoes the double helix of DNA — a structure that has been central to her career-long quest to uncover genes underlying neurological conditions. As the institute’s director — and as a scientist— she is known for going beyond the standard job description. Genetics researchers often cast a wide net and sequence thousands of genes at a time. But in her prolific career, Zoghbi has focused on a handful of genes, methodically building up an understanding of their function one careful step at a time. Thanks to that approach, Zoghbi has made a number of landmark discoveries, including identifying the genetic roots of Rett syndrome, an autism-related condition that primarily affects girls, as well as the genetic mutations that spur spinocerebellar ataxia, a degenerative motor condition. She has authored more than 350 journal articles. Her accomplishments have earned her almost every major biology and neuroscience research award, including the prestigious Breakthrough Prize in 2017 and the Brain Prize in 2020. “She’s clearly the international leader in the field,” said the late Stephen Warren, professor of human genetics at Emory University in Atlanta, Georgia. Zoghbi never set out to lead a large research center, she says — her heart is in the lab. -
Gruber Foundation Formed at Yale Yale Joins Sloan Digital Sky Survey
Yale University Astronomy Department Newsletter Vol. 3 Fall 2011 No. 1 Yale joins Sloan Digital Sky Survey III Yale is now a fully participating member of the Sloan Digital Sky Survey III (SDSS-III) Collaboration. Although Yale was not a member during the first two phases of SDSS, the suc- cess of SDSS and the excitement of Yale astronomers about the projects and data of SDSS-III led Yale to join now. Based on citations in refereed articles and meeting abstracts, SDSS has been rated as the telescope project with the biggest sci- entific impact in history, beating out even the Hubble Space Telescope and the Keck Telescopes (c.f. Madrid, Juan P. and Macchetto, Duccio 2009arXiv0901.4552M). The previous incarnations of SDSS have imaged 13,000 square degrees, corresponding to about a third of the en- tire sky. SDSS-III is taking spectra of interesting objects that were found in these images, through a program of four sur- veys that cover three scientific themes. The Baryon Oscil- lation Spectroscopic Survey (BOSS) studies dark energy and the geometry of space. (SEE SDSS-III, p. 4) SDSS-III Data Release 8 image from January 2011 Gruber Foundation formed at Yale with prizes and fellowships in astronomy and cosmology In May of 2011, Patricia and Peter Gruber officially formed the Gruber Founda- tion at Yale University, dedicated to the advancement of science, support of young scientists, global justice, and women’s rights. The Gruber Foundation at Yale will succeed The Peter and Patricia Gruber Foundation, originally estab- lished in 1993, and carry on its philanthropic mission, including its prestigious annual science prizes. -
2016 Joint Meeting Program
April 15 – 17, 2016 Fairmont Chicago Millennium Park • Chicago, Illinois The AAP/ASCI/APSA conference is jointly provided by Boston University School of Medicine and AAP/ASCI/APSA. Meeting Program and Abstracts www.jointmeeting.org www.jointmeeting.org Special Events at the 2016 AAP/ASCI/APSA Joint Meeting Friday, April 15 Saturday, April 16 ASCI President’s Reception ASCI Food and Science Evening 6:15 – 7:15 p.m. 6:30 – 9:00 p.m. Gold Room The Mid-America Club, Aon Center ASCI Dinner & New Member AAP Member Banquet Induction Ceremony (Ticketed guests only) (Ticketed guests only) 7:00 – 10:00 p.m. 7:30 – 9:45 p.m. Imperial Ballroom, Level B2 Rouge, Lobby Level How to Solve a Scientific Puzzle: Speaker: Clara D. Bloomfield, MD Clues from Stockholm and Broadway The Ohio State University Comprehensive Cancer Center Speaker: Joe Goldstein, MD APSA Welcome Reception & University of Texas Southwestern Medical Center at Dallas Presidential Address APSA Dinner (Ticketed guests only) 9:00 p.m. – Midnight Signature Room, 360 Chicago, 7:30 – 9:00 p.m. John Hancock Center (off-site) Rouge, Lobby Level Speaker: Daniel DelloStritto, APSA President Finding One’s Scientific Niche: Musings from a Clinical Neuroscientist Speaker: Helen Mayberg, MD, Emory University Dessert Reception (open to all attendees) 10:00 p.m. – Midnight Imperial Foyer, Level B2 Sunday, April 17 APSA Future of Medicine and www.jointmeeting.org Residency Luncheon Noon – 2:00 p.m. Rouge, Lobby Level 2 www.jointmeeting.org Program Contents General Program Information 4 Continuing Medical Education Information 5 Faculty and Speaker Disclosures 7 Scientific Program Schedule 9 Speaker Biographies 16 Call for Nominations: 2017 Harrington Prize for Innovation in Medicine 26 AAP/ASCI/APSA Joint Meeting Faculty 27 Award Recipients 29 Call for Nominations: 2017 Harrington Scholar-Innovator Award 31 Call for Nominations: George M. -
Gravity's Fatal Attraction
Cambridge University Press 978-0-521-71793-9 - Gravity’s Fatal Attraction: Black Holes in the Universe, Second Edition Mitchell Begelman and Martin Rees Frontmatter More information GRAVITY’S FATAL ATTRACTION Black Holes in the Universe Second edition Richly illustrated with the images from observatories on the ground and in space, and computer simulations, this book shows how black holes were discovered, and discusses our current understanding of their role in cosmic evolution. This second edition covers new discoveries made in the past decade, including defi nitive proof of a black hole at the center of the Milky Way, evidence that the expansion of the Universe is accelerating, and the new appreciation of the connection between black holes and galaxy formation. There are entirely new chapters on gamma-ray bursts and cosmic feedback. Begelman and Rees blend theoretical arguments with observa- tional results to demonstrate how both have contributed to the subject. Clear, explanatory illustrations and photographs reveal the strange and amazing workings of our Universe. The engaging style makes this book suitable for introductory undergraduate courses, amateur astronomers, and all readers interested in astronomy and physics. Mitchell Begelman is Chairman of the Department of Astrophysical and Planetary Sciences and Fellow of JILA, at the University of Colorado at Boulder. He has won several awards, including the Guggenheim Fel- lowship, Sloan Research Fellowship, and the American Astronomical Society Warner Prize. Martin Rees is Professor of Cosmology and Astrophysics and Master of Trinity College at Cambridge University, and Astronomer Royal. He is a winner of the Gold Medal of the Royal Astronomical Society and other awards. -
10. Scientific Programme 10.1
10. SCIENTIFIC PROGRAMME 10.1. OVERVIEW (a) Invited Discourses Plenary Hall B 18:00-19:30 ID1 “The Zoo of Galaxies” Karen Masters, University of Portsmouth, UK Monday, 20 August ID2 “Supernovae, the Accelerating Cosmos, and Dark Energy” Brian Schmidt, ANU, Australia Wednesday, 22 August ID3 “The Herschel View of Star Formation” Philippe André, CEA Saclay, France Wednesday, 29 August ID4 “Past, Present and Future of Chinese Astronomy” Cheng Fang, Nanjing University, China Nanjing Thursday, 30 August (b) Plenary Symposium Review Talks Plenary Hall B (B) 8:30-10:00 Or Rooms 309A+B (3) IAUS 288 Astrophysics from Antarctica John Storey (3) Mon. 20 IAUS 289 The Cosmic Distance Scale: Past, Present and Future Wendy Freedman (3) Mon. 27 IAUS 290 Probing General Relativity using Accreting Black Holes Andy Fabian (B) Wed. 22 IAUS 291 Pulsars are Cool – seriously Scott Ransom (3) Thu. 23 Magnetars: neutron stars with magnetic storms Nanda Rea (3) Thu. 23 Probing Gravitation with Pulsars Michael Kremer (3) Thu. 23 IAUS 292 From Gas to Stars over Cosmic Time Mordacai-Mark Mac Low (B) Tue. 21 IAUS 293 The Kepler Mission: NASA’s ExoEarth Census Natalie Batalha (3) Tue. 28 IAUS 294 The Origin and Evolution of Cosmic Magnetism Bryan Gaensler (B) Wed. 29 IAUS 295 Black Holes in Galaxies John Kormendy (B) Thu. 30 (c) Symposia - Week 1 IAUS 288 Astrophysics from Antartica IAUS 290 Accretion on all scales IAUS 291 Neutron Stars and Pulsars IAUS 292 Molecular gas, Dust, and Star Formation in Galaxies (d) Symposia –Week 2 IAUS 289 Advancing the Physics of Cosmic -
277 — 18 January 2016 Editor: Bo Reipurth ([email protected]) List of Contents
THE STAR FORMATION NEWSLETTER An electronic publication dedicated to early stellar/planetary evolution and molecular clouds No. 277 — 18 January 2016 Editor: Bo Reipurth ([email protected]) List of Contents The Star Formation Newsletter Interview ...................................... 3 Abstracts of Newly Accepted Papers ........... 5 Editor: Bo Reipurth [email protected] Abstracts of Newly Accepted Major Reviews . 30 Technical Editor: Eli Bressert Dissertation Abstracts ........................ 31 [email protected] New Jobs ..................................... 32 Technical Assistant: Hsi-Wei Yen Meetings ..................................... 33 [email protected] Summary of Upcoming Meetings ............. 36 Editorial Board Joao Alves Alan Boss Jerome Bouvier Cover Picture Lee Hartmann Thomas Henning The Rosette Nebula is a large HII region in Mono- Paul Ho ceros at a distance of about 1.6 - 1.7 kpc. It is Jes Jorgensen illuminated by the OB cluster NGC 2244, which Charles J. Lada contains seven O-stars, dominated by the O4V star Thijs Kouwenhoven HD 46223. The northwestern edge of the HII region Michael R. Meyer contains a large complex of globules and elephant Ralph Pudritz trunks. Luis Felipe Rodr´ıguez Ewine van Dishoeck Image courtesy Don Goldman http://astrodonimaging.com Hans Zinnecker ( ). The Star Formation Newsletter is a vehicle for fast distribution of information of interest for as- tronomers working on star and planet formation and molecular clouds. You can submit material for the following sections: Abstracts of recently Submitting your abstracts accepted papers (only for papers sent to refereed journals), Abstracts of recently accepted major re- Latex macros for submitting abstracts views (not standard conference contributions), Dis- and dissertation abstracts (by e-mail to sertation Abstracts (presenting abstracts of new [email protected]) are appended to Ph.D dissertations), Meetings (announcing meet- each Call for Abstracts. -
An Eye to the Future Advances in Imaging Are Accelerating the Pace of Biological Discovery
fall 2007 An Eye to the Future Advances in imaging are accelerating the pace of biological discovery. A new cellular imaging initiative at the University has researchers seeing small and thinking big. story on page 8 p r o f i l e s college News c l a s s N o t e s from the dean Where curiosity- and solution- driven science meet ome scientists are driven by a curiosity to under- As a curiosity-driven college, it’s CBS’ job to keep S stand how life works—from molecules to eco- adding to the foundation of knowledge that supports systems—and to add to the world’s collective body of translational and solution-driven science in other col- knowledge. Others are searching for a puzzle piece leges. As such, we are the stewards of the foundational that may yield a better way to treat cancer, produce disciplines in the biological sciences: biochemistry, food or create renewable forms of energy. molecular biology, genetics, cell biology and develop- ment, ecology, plant biology, etc. Both are essential, and there is plenty of overlap Robert Elde, Dean between the two. Curiosity-driven research often turns In order to keep fueling translational and solution- up a bit of information that has immediate applications driven research, we need to infuse foundational disci- in medicine, agriculture or engineering. By the same plines with new technologies and other opportunities token, solution-driven research can add to knowledge. as science evolves. And some scientists travel between these two worlds. Fall 07 Vol. 5 No. 3 Cellular imaging, the subject of our cover story, is one As a whole, College of Biological Sciences faculty of those opportunities. -
View Final Program
142nd ANNUAL MEETING OF THE AMERICAN ANA2017 NEUROLOGICAL ASSOCIATION SAN DIEGO, CA • OCTOBER 15-17, 2017 SHERATON SAN DIEGO HOTEL & MARINA EXPLORE • EXAMINE • INVESTIGATE FINAL PROGRAM OCTOBER 14, 2017 | Pre-Meeting Symposium: Big Science and the BRAIN Initiative 2017.MYANA.org 142nd ANNUAL MEETING OF THE AMERICAN ANA2017 NEUROLOGICAL ASSOCIATION SAN DIEGO, CA • OCTOBER 15 -17, 2017 SHERATON SAN DIEGO HOTEL & MARINA ND Please note some session titles may have changed since this program was printed. Please refer THE 142 ANA to your Mobile app for the most current session updates. ANNUAL MEETING LETTER FROM THE CHAIR 3 Enjoy outstanding scientific SCHEDULE AT A GLANCE 4 symposia covering the latest HOTEL FLOOR PLANS 6 research in the fields of neurology and neuroscience GENERAL INFORMATION 7 while taking the opportunity WIRELESS CONNECTION 8 to network with leaders in the world of academic neurology CONTINUING MEDICAL EDUCATION 8 at the 142nd ANA Annual ANNUAL MEETING MOBILE APP 8 Meeting in San Diego, CA, October 15-17, 2017. PROGRAMS BY DAY 9 SATURDAY OCT 14 9 MEETING LOCATION SUNDAY OCT 15 9 Sheraton San Diego MONDAY OCT 16 17 Hotel & Marina 1380 Harbor Island Drive TUESDAY OCT 17 25 San Diego, California 92101 IN MEMORIAM 28 ONSITE MEETING CONTACTS SPEAKER ABSTRACTS 29 Registration and meeting questions: THANK YOU TO OUR SUPPORTERS & EXHIBITORS 42 [email protected] FUTURE MEETING DATES 42 OR visit the registration desk Bay View Foyer 2017 AWARDEES 43 (located in Marina Tower Lobby Level) ACADEMIC NEUROLOGY REPRESENTATIVES FROM JAPAN 47 Saturday, October 14 2017 ABSTRACT REVIEWERS 48 3:00 PM–7:00 PM BOARD OF DIRECTORS 49 Sunday, October 15 6:00 AM–5:45 PM ANA 2017 COMMITTEES, SUBCOMMITTEES & TASK FORCES 50 Monday, October 16 6:30 AM–5:45 PM Tuesday, October 17 6:30 AM–2:15 PM #ANAMTG2017 ANA 2017 FROM THE CHAIR Dear Colleagues, It is a pleasure to welcome you to the 142nd Annual Meeting of the American Neurological Association (ANA). -
Yale Law School 2019–2020
BULLETIN OF YALE UNIVERSITY BULLETIN OF YALE BULLETIN OF YALE UNIVERSITY Periodicals postage paid New Haven ct 06520-8227 New Haven, Connecticut Yale Law School 2019–2020 Yale Law School Yale 2019–2020 BULLETIN OF YALE UNIVERSITY Series 115 Number 11 August 10, 2019 BULLETIN OF YALE UNIVERSITY Series 115 Number 11 August 10, 2019 (USPS 078-500) The University is committed to basing judgments concerning the admission, education, is published seventeen times a year (one time in May and October; three times in June and employment of individuals upon their qualifications and abilities and a∞rmatively and September; four times in July; five times in August) by Yale University, 2 Whitney seeks to attract to its faculty, sta≠, and student body qualified persons of diverse Avenue, New Haven CT 06510. Periodicals postage paid at New Haven, Connecticut. backgrounds. In accordance with this policy and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment Postmaster: Send address changes to Bulletin of Yale University, against any individual on account of that individual’s sex, race, color, religion, age, PO Box 208227, New Haven CT 06520-8227 disability, status as a protected veteran, or national or ethnic origin; nor does Yale discriminate on the basis of sexual orientation or gender identity or expression. Managing Editor: Kimberly M. Go≠-Crews University policy is committed to a∞rmative action under law in employment of Editor: Lesley K. Baier women, minority group members, individuals with disabilities, and protected veterans. PO Box 208230, New Haven CT 06520-8230 Inquiries concerning these policies may be referred to Valarie Stanley, Director of the O∞ce for Equal Opportunity Programs, 221 Whitney Avenue, 4th Floor, 203.432.0849.