Bulletin 2021-22 Department of Neuroscience (09/29/21)

Associate Professor of Neurobiology in Neurological Surgery Department of PHD University of Zurich 1977 MS University of Zurich 1973 Neuroscience Harold Burton, PHD Professor of Neuroscience (primary appointment) The Department of Neuroscience plays a key role in Professor of Biomedical Engineering the development and teaching of basic sciences in the Professor of Cell Biology and Physiology Medical School Gateway curriculum (https://sites.wustl.edu/ Professor of Radiology gatewaycurriculum/), including human anatomy, histology, PHD Univ of Wisconsin Madison 1968 and neuroscience. In conjunction with the Division of Biology BA University of Michigan 1964 & Biomedical Sciences (DBBS) program in neuroscience, the department also offers introductory graduate courses in C cellular, molecular, and systems neuroscience (http:// Valeria Cavalli, MS, PHD neuroscienceprogram.wustl.edu/Program/-Curriculum/). In Professor of Neuroscience (primary appointment) addition, the department also offers a number of advanced MS University of Geneva 1992 courses that are primarily designed for graduate students but PHD University of Geneva 2000 that are also open to students in the medical curriculum. Finally, BS University of Geneva 1991 advanced elective research activities are offered by faculty in the department. Yao Chen, MS, PHD Assistant Professor of Neuroscience (primary appointment) Website: http://neuroscience.wustl.edu Assistant Professor of Cell Biology and Physiology MS Cambridge University 2006 Faculty BS Cambridge University 2002 Linda J. Richards AO, FAA, FAHMS, PhD PHD Harvard University 2009 Department Chair D Visit our website for more information about our faculty (http:// Krikor T Dikranian, PHD, MD neurosci.wustl.edu/People/Faculty/) and their appointments. Professor of Anatomy (primary appointment) Professor of Physical Therapy A PHD Medical University - Sofia 1992 MD Medical University - Varna 1978 Kari Leigh Allen, MA, PHD Assistant Professor of Anatomy (primary appointment) F Assistant Professor of Anthropology (Courtesy) James Alexander John Fitzpatrick, PHD MA New Mexico St University 2008 Professor of Neuroscience (primary appointment) PHD Duke University 2014 Professor of Cell Biology and Physiology BA State Univ of NY Potsdam 2005 BS King's College London 2000 B PHD University of Bristol 2003 Amy Lynn Bauernfeind, PHD, M PHIL Susan M Fitzpatrick, PHD Associate Professor of Anatomy (primary appointment) Adjunct Associate Professor of Neuroscience (primary Associate Professor of Anthropology (Courtesy) appointment) BS Vanderbilt University 2004 Adjunct Associate Professor of Occupational Therapy PHD George Washington University 2014 PHD Cornell University 1984 M PHIL George Washington University 2011 BS St Johns University 1978 Paul C Bridgman, PHD, MS G Professor of Neuroscience (primary appointment) Harrison W. Gabel, AB, PHD Associate Professor of Biomedical Engineering Assistant Professor of Neuroscience (primary appointment) BA University of San Diego 1974 AB Princeton University 2001 PHD Purdue University 1980 PHD Harvard University 2008 MS University of CA San Diego 1976 Andreas H Burkhalter, PHD, MS H Professor of Neuroscience (primary appointment) Edward B. Han, PHD Associate Professor of Biomedical Engineering Assistant Professor of Neuroscience (primary appointment)

1 Bulletin 2021-22 Department of Neuroscience (09/29/21)

Assistant Professor of Anesthesiology BS University of CA Davis 1984 BS Cornell University 1995 PHD University of CA San Diego 2004 O Martha B. Han, PHD Karen Laurel O'Malley, PHD, MS Assistant Professor of Neuroscience (primary appointment) Professor of Neuroscience (primary appointment) PHD University of CA San Diego 2008 PHD University of Texas Austin 1980 BS Yale University 2000 MS Portland St University 1973 BA Sonoma State University 1971 Timothy E. Holy, MA, PHD Professor of Neuroscience (primary appointment) P Alan A and Edith L Wolff Professor of Neuroscience Camillo Padoa-Schioppa, PHD, MS BA Rice University 1991 Professor of Neuroscience (primary appointment) MA Princeton University 1992 Professor of Biomedical Engineering PHD Princeton University 1997 Professor of Economics (Courtesy) J PHD Mass Inst of Technology (MIT) 2002 MS La Sapienza University 1996 Ahmad Jezzini, MS, PHD Instructor in Neuroscience (primary appointment) Thomas J Papouin, PHD, MS MS Univ Claude Bernard Lyon 1 2004 Assistant Professor of Neuroscience (primary appointment) PHD University of Parma 2010 BS Ecole Normale Superieure Lyon 2005 BS Lebanese Univ Med Science 2003 PHD University of Bordeaux 2 2011 MS Ecole Normale Superieure Lyon 2007 K Carlos Ramon Ponce, MD, PHD Adam Kepecs, PHD Assistant Professor of Neuroscience (primary appointment) Professor of Neuroscience (primary appointment) BS University of Utah 2001 Professor of Psychiatry MD Harvard University 2010 Robert J Terry Professor of Neuroscience PHD Harvard University 2008 BS Eötvös Loránd University 1997 PHD Brandeis University 2002 R Linda J Richards, PHD L Edison Professor of Neurobiology (primary appointment) Qingyun Li, PHD Head of the Department of Neuroscience Assistant Professor of Neuroscience (primary appointment) PHD Walter & Eliza Hall Institute 1994 Assistant Professor of Genetics BS Walter & Eliza Hall Institute 1990 BA China Agriculture University 2006 Terrence Bradley Ritzman, MA, PHD PHD Duke University 2015 Assistant Professor of Anatomy (primary appointment) M Assistant Professor of Anthropology BA University of Illinois 1999 Ilya E. Monosov, MS, PHD MA Colorado St University 2005 Associate Professor of Neuroscience (primary appointment) PHD Arizona State University 2014 Associate Professor of Neurological Surgery MS NewSchool Architecture Design 2005 S PHD Brown University 2009 Lawrence B Salkoff, PHD BS University of CA San Diego 2004 Professor of Neuroscience (primary appointment) Ashley C. Morhardt, PHD, MS Professor of Genetics Assistant Professor of Anatomy (primary appointment) BA University of CA Los Angeles 1967 BS Illinois College, Jacksonville 2006 PHD University of CA Berkeley 1979 PHD Ohio University 2016 Paul Joseph Shaw, PHD, MA MS Western Illinois University 2009 Professor of Neuroscience (primary appointment) N PHD University of Chicago 1996 MA San Jose State University 1990 Michael L Nonet, PHD BA Niagara University 1985 Associate Professor of Neuroscience (primary appointment) PHD Mass Inst of Technology (MIT) 1989 Lawrence H Snyder, PHD, MD, MS, AB

2 Bulletin 2021-22 Department of Neuroscience (09/29/21)

Professor of Neuroscience (primary appointment) Professor of Psychological & Brain Sciences Martha Bagnall, PhD PHD University of Rochester 1992 McDonnell Medical Sciences Building, 4th Floor MD University of Rochester 1992 Phone: 314-362-9695 MS University of Rochester 1992 Molecular, electrophysiological, and behavioral analyses of AB Princeton University 1982 neural circuits for vestibular control of spinal function T Paul H Taghert, PHD Amy Bauernfeind, PhD Professor of Neuroscience (primary appointment) North Building, 3rd Floor PHD University of Washington 1981 Phone: 314-747-6566 BA Reed College 1975 Biological bases of human cognition; comparative neurobiology Gaia Tavoni, PHD of primates Assistant Professor of Neuroscience (primary appointment) Assistant Professor of Medicine Paul Bridgman, PhD BS Polytechnic University of Turi 2010 McDonnell Medical Sciences Building, 8th Floor PHD Ecole Normale Superieure Lyon 2015 Phone: 314-362-3449 V Cell biology of the developing nervous system David C Van Essen, PHD Alumni Endowed Professor of Neurobiology (primary Andreas Burkhalter, PhD appointment) North Building, 4th Floor Professor of Biomedical Engineering Phone: 314-362-4068 BS California Institute Technolo 1967 Organization and function of neuronal circuits in mouse visual PHD Harvard University 1971 cortex Y Jason Yi, PHD Harold Burton, PhD Assistant Professor of Neuroscience (primary appointment) East McDonnell Building, 3rd Floor BS Dickinson College 2001 Phone: 314-362-3556 PHD Duke University 2009 Cortical functional reorganization in response to sensory Z changes due to unilateral deafness or strabismus Guoyan Zhao, MS, PHD Assistant Professor of Neuroscience (primary appointment) Valeria Cavalli, PhD MS School Not Listed 1998 McDonnell Medical Sciences Building, 9th Floor PHD Washington Univ in St. Louis 2003 Phone: 314-362-3540 BS School Not Listed 1995 Cellular, molecular and epigentic mechanisms controlling axon Research Electives regeneration

Neuroscience Research Electives Yao Chen, PhD During the fourth year, opportunities exist for many varieties of McDonnell Medical Sciences Building, 9th Floor advanced clinical or research experiences. Phone: 314-273-7739 We aim to understand how the dynamics of neuromodulators Kari Allen, PhD and intracellular signals contribute to the function of North Building, 3rd Floor neuromodulators, to learning, and to the function of sleep. Phone: 314-747-6572 Paleoanthropology and phylogenetic statistics; comparative Krikor Dikranian, MD, PhD analyses of primate craniodental morphology and the evolution North Building, 3rd Floor of brain size Phone: 314-362-3548

3 Bulletin 2021-22 Department of Neuroscience (09/29/21)

Development and morphology of the amyloid plaques in experimental animals; neuropathological changes after head Ashley Morhardt, PhD trauma North Building, 3rd Floor Phone: 314-273-1859 James Fitzpatrick, PhD Evolution of neural diversity within and across non-mammalian McKinley Research Building, Basement vertebrate clades, especially dinosaurs Phone: 314-747-0838 Optical and charged particle multiscale microscopy application Michael L. Nonet, PhD method development McDonnell Medical Sciences Building, 9th Floor Phone: 314-747-1176

Harrison Gabel, PhD Molecular genetic analysis of synaptic development and function McDonnell Medical Sciences Building, 8th Floor Phone: 314-362-3531 Karen L. O’Malley, PhD Gene regulation in the developing nervous system; molecular McDonnell Medical Sciences Building, 9th Floor mechanisms of neurodevelopmental disorders Phone: 314-362-7087 Molecular mechanisms underlying neurodegenerative Edward Han, PhD processes; signaling mechanisms associated with intracellular McDonnell Medical Sciences Building, 9th Floor receptors Phone: 314-747-2505 Learning-related hippocampal network activation Camillo Padoa Schioppa, PhD East McDonnell Building, 3rd Floor Phone: 314-362-3530 Timothy E. Holy, PhD North Building, 4th Floor Neuronal bases of economic choice and decision making Phone: 314-362-0086 Neural mechanisms of action of mammalian pheromones Thomas Papouin, PhD McDonnell Medical Sciences Building, 9th Floor Phone: 314-273-7738 Adam Kepecs, PhD McDonnell Medical Sciences Building, 4th Floor Role played by the 80% to 90% of non-neuronal cells (glial cells) Phone: 314-273-8523 in brain function Our long-term goal is to reverse engineer the computational and neurobiological processes underlying cognition and decision- Carlos Ponce, MD, PhD making and apply these insights to biological psychiatry. East McDonnell Building, 2nd Floor Phone: 314-273-2746 Tristan (Qingyun) Li, PhD The goal of our lab is to define how neurons from different McDonnell Medical Sciences Building, 8th Floor cortical areas interact to realize our perception of shape and Phone: 314-273-1422 motion. My lab is broadly interested in neuroimmunology, with a focus on microglial biology. We combine cutting-edge, single- Linda J. Richards AO, FAA, FAHMS, PhD cell genomic technologies with in vitro and in vivo genetic, McDonnell Medical Sciences Building, 9th Floor molecular, and cellular tools to investigate microglial functions Phone: 314-362-3033 in the establishment of the nervous system, and we study how The Brain Development and Disorders Laboratory investigates changes in these functions contribute to neurological diseases. how long-range neural circuits are established in the brain and how neural circuit plasticity affects the function of the cerebral Ilya Monosov, MS, PhD cortex. East McDonnell Building, 2nd Floor Phone: 314-362-3740 Terry Ritzman, PhD Neuronal mechanisms of voluntary behavior North Building, 3rd Floor Phone: 314-273-1861

4 Bulletin 2021-22 Department of Neuroscience (09/29/21)

Comparative anatomy of the skull in primates as it relates to human evolution Guoyan Zhao, PhD McDonnell Medical Sciences Building, 8th Floor Phone: 314-273-9045 Lawrence B. Salkoff, PhD McDonnell Medical Sciences Building, 9th Floor My laboratory is interested in understanding the regulatory Phone: 314-362-3644 networks that control the development and proper function of mammalian brains in the context of human health and disease. Roles of ion channels in neuronal long-term excitability changes

Paul J. Shaw, PhD Courses McDonnell Medical Sciences Building, 9th Floor Visit online course listings to view offerings for M05 Neurosci Phone: 314-362-2703 (https://courses.wustl.edu/CourseInfo.aspx?sch=M&dept=M05). Molecular genetics of sleep and circadian rhythms M05 Neurosci 554 Neural Science Lawrence H. Snyder, MD, PhD This is an intensive seven-week course that covers the structure, East McDonnell Building, 3rd Floor development, and function of the nervous system as seen from molecular, cellular, and systems-oriented perspectives. The Phone: 314-747-3530 emphasis is on the organization and function of the nervous Computational and cognitive issues in cortical control of eye and system in health, but there is frequent reference to the clinical relevance of the material presented. The course includes regular arm movement investigated via electrophysiology and imaging lectures, conference sessions, and laboratories (including a team based learning session), plus a number of clinically oriented presentations and special topics sessions that address selected Paul H. Taghert, PhD issues in greater depth. Computer-aided instructional programs, McDonnell Medical Sciences Building, 9th Floor which are accessible from a variety of locations, provide auxiliary Phone: 314-362-3641 modes of self-paced learning and review. Exams emphasize the core body of important facts and principles presented in the Neurobiology of circadian rhythms; neurobiology of peptidergic lectures and laboratories. Limited space is available for non- neurotransmission medical students with the instructor's permission. Non-medical students should register under the cross-listed number L41 554. Spring only. Gaia Tavoni Credit 109 units. East McDonnell Building, 3rd Floor Phone: 314-362-3590 M05 Neurosci 810 Advanced Dissection Students will perform detailed dissections on a discrete region Applying concepts and methods from statistical mechanics, of the body of their choosing-i.e. head/neck, thorax, abdomen, Bayesian theory, mathematics and biophysics to the study of the pelvic cavity, or limbs. Students will compile a list of personal brain learning objectives with approval of the course director(s). A minimum of 30hrs of self-paced individual dissection is required and may include practice of surgical approaches, and/or study of David C. Van Essen, PhD cross-sectional anatomy and medical imaging. East McDonnell Building, 2nd Floor Phone: 314-362-7043 L41 Biol 5622 Cognitive, Computational, and Systems Organization, function, and development of primate cerebral Neuroscience Project Building cortex, especially in humans; generation and utilization of The goal of this course is to help students in the CCSN Pathway develop the critical thinking skills necessary to develop and neuroinformatics tools for data mining implement high quality, interdisciplinary research projects. Throughout the course of the semester, each student will develop a research plan in their chosen area of interest. The Jason Yi, PhD plan will be developed in consultation with at least two faculty McDonnell Medical Sciences Building, 8th Floor members (from at least two different subdisciplines within the Phone: 314-273-1664 pathway) as well as the other students and faculty participating in the course. The culmination of this course will be for each Molecular pathways shaping nervous system development and student to produce an NIH-style grant proposal on the research function project of their choosing. For most students, this will serve either as their thesis proposal or a solid precursor to the thesis proposal. The course will be designed to help facilitate the development of such a research plan through didactic work, class presentations, class discussion, and constructive feedback on written work. The course will begin with a review of written

5 Bulletin 2021-22 Department of Neuroscience (09/29/21)

examples of outstanding research proposals, primarily in the form of grant submissions similar to those that the students are expected to develop (i.e., NRSA style proposals, R03 proposals). Review of these proposals will serve as a stimulus to promote discussion about the critical elements of good research proposals and designs in different areas. Each student will be expected to give three presentations throughout the semester that will provide opportunities to receive constructive feedback on the development and implementation of research aims. The first presentation (towards the beginning of the semester) will involve presentation of the student's general topic of interest and preliminary formulation of research questions. Feedback will emphasize ways to focus and develop the research hypotheses into well-formulated questions and experiments. The second presentation will involve a more detailed presentation of specific research questions (along the lines of NIH-style Specific Aims) and an initial outline of research methods. The final presentation will involve a fuller presentation of research questions and proposed methods. Feedback, didactic work, and group discussion throughout the semester will include guidance on critical components of the development of a research plan, including how to perform literature searches, formulate testable hypotheses, write critical literature summaries, and design experiments and analyses. The course will meet once a week, with faculty members from different tracks within the Pathway present at each meeting. This will allow students to receive feedback from several perspectives. Prerequisite: Member of CCSN Pathway, permission of instructor. Credit 3 units.

6