Multiscale PHATE Exploration of SARS-Cov-2 Data Reveals Multimodal Signatures of Disease
bioRxiv preprint doi: https://doi.org/10.1101/2020.11.15.383661; this version posted November 17, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Multiscale PHATE Exploration of SARS-CoV-2 Data Reveals Multimodal Signatures of Disease Manik Kuchroo1∗, Jessie Huang2∗, Patrick Wong3∗, Jean-Christophe Grenier4, Dennis Shung5, Alexander Tong2, Carolina Lucas3, Jon Klein3, Daniel Burkhardt6, Scott Gigante7, Abhinav Godavarthi8, Benjamin Israelow3, Tianyang Mao3, Ji Eun Oh3, Julio Silva3, Takehiro Takahashi3, Camila D. Odio5, Arnau Casanovas-Massana9, John Fournier10, Yale IMPACT Team11, Shelli Farhadian10, Charles S. Dela Cruz12, Albert I. Ko9, F. Perry Wilson13, Julie Hussin4;14x, Guy Wolf15;16x, Akiko Iwasaki3;17x;y and Smita Krishnaswamy2;6x;y 1Department of Neuroscience, Yale University, New Haven, CT, 2Department of Computer Science, Yale University, New Haven, CT, 3Department of Immunobiology, Yale University, New Haven, CT, 4Montreal Heart Institute, Montréal, Québec, Canada, 5Department of Medicine, Yale University, New Haven, CT, 6Department of Genetics, Yale University, New Haven, CT, 7Computational Biology, Bioinformatics Program,Yale University, New Haven, CT, 8Department of Applied Mathematics, Yale University, New Haven, CT, 9Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 10Department
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