International Symposium on Metastases in Head and Neck Cancer

6th International Symposium on Metastases in Head and Neck Cancer

1st Satellite Symposium on Arterio-venous Malformations of the Head and Neck

Advisory Board Al-Nawas, Bilal (Mainz, Germany) Brakenhoff, Ruud (Amsterdam, The Netherlands) Budach, Volker (Berlin, Germany) Buscombe, John (Cambridge, United Kingdom) Civantos, Francisco (Miami, USA) De Bree, Remco (Amsterdam, The Netherlands) Dietz, Andreas (Leipzig, Germany) Eckel, Hans-Edmund (Klagenfurt, Austria) Folz, Benedikt (Bad Lippspringe, Germany) Golusinski, Wojciech (Poznan, Poland) Gullane, Patrick (Toronto, Canada) Hambek, Markus (Frankfurt, Germany) Holsinger, Chris (Houston, USA) Hölzel, Dieter (München, Germany) Iro, Heinrich (Erlangen, Germany) Knecht, Rainald (Hamburg, Germany) Lai, Yinyan (Guangzhou, China) Lang, Stefan (Essen, Germany) Lawson, George (Yvoir, Belgium) Lippert, Burkard (Heilbronn, Germany) McGurk, Mark (London, United Kingdom) Negm, Hesham (Cairo, Egypt) Olofsson, Jan (Bergen, Norway) Pepe, Graciela (Corrientes, Argentina) Remacle, Marc (Yvoir, Belgium) Shah, Jatin (New York, USA) Staar, Susanne (Bremen, Germany) Stoeckli, Sandro (St. Gallen, Switzerland) Suen, James (Little Rock, USA) Szyfter, Krzysztof (Poznan, Poland) Szyfter, Witold (Poznan, Poland) Whiteside, Theresa (Pittsburgh, USA) Wittekind, Christian (Leipzig, Germany) Wollenberg, Barbara (Lübeck, Germany)

Faculty of Marburg Eivazi, Behfar Engenhart-Cabillic, Rita Kirschbaum, Andreas Mandapathil, Magis Mandic, Robert Neff, Andreas Roeßler, Marion Teymoortash, Afshin Wiegand, Susanne

Chairman Werner, Jochen A.

CONTENTS

Page

Welcome address ...... 4

Anneliese Pohl Comprehensive Cancer Center ...... 5

General information ...... 6

Instructions for presentations ...... 8

Social events ...... 9

Timetable ...... 10

Scientific program (Thursday, January 24, 2013) ...... 11

Scientific program (Friday, January 25, 2013) ...... 13

Scientific program (Saturday, January 26, 2013) ...... 17

Scientific program (Sunday, January 27, 2013) ...... 21

Posters ...... 22

Lecturers, Panellists, and Chairpersons ...... 24

Industrial exhibitors and donators ...... 26

Impressum ...... 28

WELCOME ADDRESS

Dear Colleagues,

I am very happy to invite you to our 6th International Symposium on Metastases in Head and Neck Cancer that takes place in Marburg from January 24-27, 2013. This time we will again discuss different questions of regional and also distant metastasis, the possibilities of their early detection, and the prognostic potential of lymph node metastases. We will discuss the provoking thesis that lymph node metastases cannot induce distant metastases and critically question the value of neck dissection on the prognosis. Within all these metastasis-related topics we will insert a real highlight of modern medicine, the transoral robotic surgery. We will offer a first contact to this new technology in the context of a hands-on training.

You will see that real controversies and innovations are presented that make the participation in this meeting an interesting event. Beside the medical and ENT-related aspects, we hope that the social events taking place in the evenings will be used as occasions to continue discussions on a more informal level and to perhaps initiate further cooperation, but most of all to allow you to recover from “a long day’s journey into the night”.

We have inserted a new module in the program which is a satellite symposium on arterio- venous malformations of the head and neck. It was especially the particular growth behaviour that moved me to include this satellite symposium in our meeting. This growth pattern often shows a rather malignant behaviour. With this background, mostly head and neck surgeons have to cope with this topic so that I am sure that it is interesting for the participants.

The whole team of the Department of Otorhinolaryngology, Head & Neck Surgery, would like to welcome you and wish you enjoyable and interesting days here in Marburg!

Jochen A. Werner Symposium Chairman

ANNELIESE POHL COMPREHENSIVE CANCER CENTER

In 2005, the Marburg Comprehensive Cancer Center (CCC) was founded based on the objective to promote the interdisciplinary cooperation of different oncologic institutions following the US American model. It is meant to be the basis to bring forward research and to translate research result from previous basic research directly to clinical treatment procedures.

In June 2012, it was renamed to Anneliese Pohl Comprehensive Cancer Center. The Faculty of Medicine and the Philipps University of Marburg recognize with this step the support and the achievements of the Honorary Senator of the Philipps University of Marburg and the Honorary Doctor of the Faculty of Medicine Prof. Dr. Dr. Reinfried Pohl and his wife Anneliese Pohl who had died in 2008.

Prof. Dr. Dr. Pohl has repeatedly supported the cancer research in Marburg and thus created an extraordinary basis for the transfer of the results directly into the medical care of patients. This step effectively strengthened the oncologic focus of the University Hospital of Marburg.

The motto of the CCC is “Cancer: Research – Teach – Cure”. The Anneliese Pohl Comprehensive Cancer Center will ensure that we better understand the mechanisms of cancer diseases and improve the curing possibilities. Prof. Pohl’s support will further be stimulus to perform more and intensive research so that more patients may be cures.

For many years now, the research and the treatment of cancer diseases is in the focus of the University medicine of Marburg. Specific appointments of professors as well as the development of the Institute for Molecular Biology and Tumor Research, founded in 1988 as part of the Philipps University, formed the basis for the institution of the focus of oncology at the Faculty of Medicine at Marburg. Beside research and patients’ care, cancer treatment is also an important part of the teaching curriculum for students so that for the first time in Germany the priority curriculum of oncology was established that finds great interest among the medical students.

GENERAL INFORMATION

Chairman J.A. Werner, M.D. Professor and Chairman Dept. of Otolaryngology, Head and Neck Surgery, University of Marburg Baldingerstr. 1, 35043 Marburg, Germany [email protected]

Program Director Afshin Teymoortash, M.D. Dept. of Otolaryngology, Head and Neck Surgery, University of Marburg Baldingerstr. 1, 35043 Marburg, Germany [email protected]

Program Co-Director Susanne Wiegand, M.D. Dept. of Otolaryngology, Head and Neck Surgery, University of Marburg Baldingerstr. 1, 35043 Marburg, Germany [email protected]

Symposium secretariat Mrs. Susanne Zapf Symposium secretariat Dept. of Otolaryngology, Head and Neck Surgery, University of Marburg Baldingerstr. 1 D-35043 Marburg, Germany Tel.: +49-6421-58-66808 Fax: +49-6421-58-66367 www.marburg-symposium.de e-mail: [email protected]

Congress venue Auditorium, University Hospital of Giessen and Marburg, Campus Marburg, Baldingerstr. 1, 35043 Marburg, Germany

Conference language English

GENERAL INFORMATION

Registration fee Fellow € 150 Resident € 80 Student free Registration on site during the symposium will be possible.

Certification Landesärztekammer Hessen certifies the participation of this meeting.

Luncheons, Tea, Coffee During breaks lunch, tea and coffee will be available free of charge in the industrial exhibition on all days. Snacks and daily changing lunch dishes are offered.

Industrial Exhibition An exhibition with displays of the latest products of the medical industry and of laboratory equipment will be arranged. The industrial exhibition will be open during all four days of the symposium, from Thursday afternoon to Sunday.

Hotel and Accommodation All participants requiring other accommodation are requested to contact: Tourist Information Marburg e.V. Postfach 2305 D-35011 Marburg Germany Tel.: +49-6421-99 120 Fax: +49-6421-99 1212 Internet: www.marburg.de e-mail: [email protected]

INSTRUCTIONS FOR PRESENTATIONS

Length of Oral Presentations

The duration of each presentation are allotted explicitly to each speaker. The chairpersons of the respective sessions will ensure strict compliance with the allotted length of the individual presentation. Lectures will be terminated in cases where the time limit is neglected significantly to allow sufficient time for discussion.

Projection Facilities

Only PowerPoint presentation is possible.

Oral presentations: Data media should be submitted at the Congress venue at least 1 hour prior to each session.

Poster Presentations

Poster boards are provided. Each poster must not measure more than 80 cm by 100 cm. The presentations of the posters will be on the assigned dates. The authors will have to be at their posters to discuss with the auditory.

SOCIAL EVENTS

January 24, 2013, 7:00 pm Welcome Reception in the Industrial Exhibition

January 25, 2013, 8:00 pm: Chairman’s Party (€ 20.00 per person, beverages included, pre-registration necessary until January 25 in the morning),

TIMETABLE

Thursday, January 24, 2013 12.00 Meeting of the German pN1 Study Group 2.30 pm Registration 3.15 pm Welcome 3.30 pm Free papers 1 5.10 pm Lecture 5.30 pm Welcome addresses 5.45 pm Lecture 6.00 pm Panel 1 7.00 pm Welcome Reception in the Industrial Exhibition

Friday, January 25, 2013 7.30 am Registration 8.00 am Free papers 2 9.45 am Key note lecture 1 10.00 am Lecture 10.30 am Coffee break 11.00 am Free papers 3 11.40 am Key note lecture 2 12.00 Key note lecture 3 12.30 pm Lunch 1.30 pm Key note lecture 4 2.00 pm Panel 2 3.00 pm Coffee break 3.30 pm Mini-Symposium 1 8.00 pm Chairman’s Party

Saturday, January 26, 2013 7.30 am Registration 8.00 am Free papers 4 9.00 am Key note lecture 5 9.30 am Panel 3 10.30 am Coffee break 11.00 am Key note lecture 6 11.30 am Mini-Symposium 2 1.00 pm Lunch 2.00 pm Panel 4 3.00 pm Key note lecture 7 3.20 pm Lecture 3.30 pm Coffee break 4.00 pm Mini-Symposium 3 5.30 pm Free papers 5 5.55 pm Poster Award 6.00 pm Panel 5

Sunday, January 27, 2013 Satellite Symposium 7.30 am Registration 9.00 am Introduction 9.15 am Lectures 10.15 am Case discussions 11.30 am Panel 1.00 pm Adjourn

PROGRAM Thursday, January 24, 2013

12.00 Meeting of the German pN1 Study Group Chair: Al Nawas B, Mainz, Germany

2.00 pm Registration

3.15 pm Welcome Werner JA, Marburg, Germany

3.30 pm Free papers 1 Chairpersons: Mandic R, Marburg, Germany; Negm H, Cairo, Egypt

1. Strieth S, Becker S, Jäger L, Eichhorn ME, Dellian M. Preliminary findings of DCE-MRI and laser Doppler flowmetry for monitoring antivascular effects in advanced head and neck cancer

2. Kreppel M, Drebber U, Zöller J, Scheer M. Podoplanin expression in oral squamous cell carcinoma

3. Negm H, Mosleh M, Fathy H, Hareedy A, Elbattawy A. Cytokeratin immunohistochemically detected nodal micrometastases in N0 laryngeal cancer: impact on the overall occult metastases

4. Almadori G, Bussu F, Galli J, Gallus R, Lauriola L, Paludetti G, Ranelletti FO. HER family of type I receptor tyrosine kinases expression and the immunohistochemical expression pattern of HER4 protein in primary laryngeal cancer: an independent prognostic factor of neck node relapse

5. Freudlsperger C, Horn D, Weichert W, Dyckhoff G, Plinkert P, Hoffmann J, Hess J, Freier K. Ex vivo tissue cultures as a preclinical model system for the treatment of head and neck squamous cell carcinoma

6. Irjala H, Marttila-Ichihara F, Karikoski M, Huovinen V, Elima K, Salmi M, Jalkanen S. Clever-1/Stabilin-1 controls both leukocyte and malignant cell traffic in cancer

7. Sproll C, Alexander M, Behrens B, Köhler D, Humbert A, Baldus SE, Kübler NR, Knoefel WT, Stoecklein NH. Detection and comprehensive molecular characterization of single disseminated tumor cells in lymph nodes and bone marrow of head and neck squamous cell carcinoma (HNSCC) patients

8. Hajiyev Y. Squamous cell carcinoma of the temporal bone: experience of a tertiary care center in Istanbul/Turkey

PROGRAM Thursday, January 24, 2013

9. Jarmuz M, Kiwerska K, Giefing M, Wierzbicka M, Szyfter W, Szyfter K. Attempts to find a reliable marker of metastasis in laryngeal squamous cell carcinoma

10. Hülsewig J, Prigge ES, Reuschenbach M, von Knebel Doeberitz M, Wagner S, Wittekindt C, Klußmann JP. Prognostic relevance of human papillomavirus (HPV) infection and expression of ß-Catenin as marker for epithelial to mesenchymal transformation (EMT) in cervical metastasis of unknown primary carcinoma (CUP)

11. Qureshi AA, Collins VP, Jani P. Genomic differences in benign and malignant follicular thyroid tumors using array-comparative genomic hybridisation

5.10 pm Chairpersons: Iro H, Erlangen, Germany; Werner JA, Marburg, Germany

N1 Neck – Report on a prospective trial Al-Nawas B, Mainz, Germany

5.30 pm Welcome addresses President of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (Iro H, Erlangen, Germany) Chairman of the German Working Group of Head and Neck Oncology (Dietz A, Leipzig, Germany)

5.45 pm The Sentinel European Node Trial McGurk M, Schilling C, London, United Kingdom

06.00 pm Panel 1 Lymph node metastases – what does this diagnosis mean for researchers and physicians? Hölzel D, München, Germany; Shah JP, New York, USA; Szyfter K, Poznan, Poland; Whiteside T, Pittsburgh, USA; Wollenberg B, Lübeck, Germany; Werner JA, Marburg, Germany

07.00 pm End of the first day

Welcome reception in the industrial exhibition

SCIENTIFIC PROGRAM Friday, January 25, 2013

07.30 am Registration

08.00 am Free papers 2 Chairpersons: Roeßler M, Marburg, Germany; Wiegand S, Marburg, Germany

1. Schroeder HG, Kollecker I, Petersen P, Donhuijsen K. Sinonasal adenocarcinoma of intestinal type (ITAC): capacity and pattern of metastasis

2. Kazi M. Management of sinonasal tumors: prognostic factors and outcomes – a 10 year experience

3. Konnerth CG, Folz BJ, Henschke F, Czyborra-Brinkmann J. Metastases in adenoid-cystic carcinoma of the head and neck

4. Cosgarea M, Chirila M, Pop S, Maniu A, Necula V, Iencica C, Terhes M, Petrescu M. Oropharyngeal cancer treatment in Cluj- Napoca ENT Department, Romania

5. Künzel J, Psychogios G, Grundtner P, Koch M, Iro H. Lymph node ratio as a valuable prognostic factor for risk stratification in patients with oropharyngeal cancer

6. Freier K, Bodem J, Engel M, Hoffmann J. Retrospective, monocenter analysis of the results of salvage surgery of advanced squamous cell carcinomas of the head and neck

7. Nisa L, Giger R. Tumor seeding to the upper chest wall in head and neck cancer: an uncommon type of metastasis

8. Schilling C. Lessons learned and recommendations for minimizing recurrence after sentinel node biopsy

9. Yeung E. Can we predict additional positive lymph nodes? Looking towards a predictive tool for diagnosis

09.45 am Key note lecture 1 Chairpersons: Wollenberg B, Lübeck, Germany; Mandapathil M, Marburg, Germany

Role of immunology in lymphogenous metastatic spread – what do we know? Whiteside T, Pittsburgh, USA

10.00 am Perspective lecture “Epithelial-mesenchymal transition (EMT) in head and neck cancer”

SCIENTIFIC PROGRAM Friday, January 25, 2013

Wollenberg B, Lübeck, Germany

10.30 am Coffee break

11.00 am Free papers 3 Chairpersons: Folz BJ, Bad Lippspringe, Germany; Golusinski W, Poznan, Poland

1. Giudice M, Gallo S, Pavan G, Ferreli F, Maffioli M, Castelnuovo P. Incidentally detected neck metastatic thyroid cancer during surgical procedures – our experience

2. Bonali M, Molteni G, Soloperto D, Ghidini A, Cioni K, Cremonini N, Presutti L. Central compartment revision surgery for persistent or recurrent thyroid carcinoma: morbidity analysis of our series

3. Wierzbicka M, Wasniewska-Okupniak E, Gurgul E, Banaszewski J, Gryczynska M, Ruchata M. Cervical recurrences in thyroid cancer. How many neck dissections can be undertaken and what is the clinical benefit?

4. Soloperto D, Mattioli F, Masoni F, Ponti G, Rossi G, Molteni G, Alicandri-Ciufelli M, Presutti L. “Collision” metastasis from unknown primary squamous cell carcinoma and papillary microcarcinoma of thyroid presenting as lateral cervical cystic mass

11.40 am Key note lecture 2 Chairpersons: Folz BJ, Bad Lippspringe, Germany; Golusinski W, Poznan, Poland

Expression and genetic profiling to predict the N status of the neck Brakenhoff R, Amsterdam, The Netherlands

12.00 Key note lecture 3 Chairpersons: Folz BJ, Bad Lippspringe, Germany; Golusinski W, Poznan, Poland

Definition of the different stages of neck node metastasis Wittekind C, Leipzig, Germany

12.30 pm Lunch

01.30 pm Key note lecture 4

SCIENTIFIC PROGRAM Friday, January 25, 2013

Chairpersons: Shah JP, New York, USA; Teymoortash A, Marburg, Germany

Do lymph node metastases metastasize? Hölzel D, Munich, Germany

02.00 pm Panel 2 Staging of the neck

Free papers 1. Heuveling DA, Visser GWM, Hoekstra OS, Leemans CR, Van Dongen GAMS, De Bree R. Introduction of the novel PET tracer 89Zr- Nanocoll for improvement of identification of the sentinel node in early stage oral cancer patients

2. Psychogios G, Mantsopoulos K, Koch M, Zenk J, Iro H. Incidence of occult cervical metastasis in head and neck carcinomas: development over time

Panel discussion De Bree R, Amsterdam, The Netherlands; McGurk M, London, United Kingdom; Stoeckli S, St. Gallen, Switzerland; Teymoortash A, Marburg, Germany; Wittekind C, Leipzig, Germany

03.00 pm Coffee break

03.30 pm Mini-Symposium 1 – Sentinel Node Chairperson: Buscombe J, Cambridge, United Kingdom

03.30 pm Opening and overview of the symposium Buscombe J, Cambridge, United Kingdom

03.40 pm Nuclear medicine overview and radiation – Safety issues in radio-guided SLNB Buscombe J, Cambridge, United Kingdom

04.10 pm Overview of SLNB in the head and neck and 3D image guidance De Bree R, Amsterdam, The Netherlands

SCIENTIFIC PROGRAM Friday, January 25, 2013

04.30 pm Background of lymphoseek Reininger C, Dublin, USA

05.00 pm US lymphoseek head and neck trial Civantos F, Miami, USA

05.30 pm Video demonstration of 3D imaging and navigation in the OR Mandapathil M, Marburg, Germany

06.00 pm The future of radio-guided surgery in head and neck malignancies McGurk M, London, United Kingdom

06.30 pm End of the second day

08.00 pm Chairman’s Party

SCIENTIFIC PROGRAM Saturday, January 26, 2013

07.30 am Registration

08.00 am Free papers 4 Chairpersons: Neff A, Marburg, Germany; Pepe G, Corrientes, Argentina

1. Flach G, Heuveling D, Bloemena C, Broglie M, de Bree R, Stoeckli S. Sentinel node biopsy in head and neck cancer patients with a previously treated neck

2. Mantsopoulos K, Psychogios G, Koch M, Waldfahrer F, Zenk J, Iro H. The importance of elective neck dissection in transorally treated early head and neck carcinomas with cN0 neck

3. Habtemichael N, Fetz V, Gößwein D, Hahlbrock A, Krempl K, Unruhe B, Pries R, Wollenberg B, Knauer SK, Stauber RH. Dissecting pathways of lymph node metastasis in head and neck cancer

4. Limani A, Limani Z, Avdiu N. Loco-regional metastasis of head and neck cancer – our experiences

5. Sharma SJ, Wagner S, Steiner D, Wittekindt C, Litzlbauer D, Klußmann JP. FDG tracer-uptake in locally advanced oropharyngeal squamous cell carcinoma

09.00 am Key note lecture 5 Chairpersons: Gullane P, Toronto, Canada; Suen J, Little Rock, USA

History and perspectives of neck dissection Shah JP, New York, USA

09.30 am Panel 3 Extent of neck dissection

Free papers 1. Eckardt AM, Kokemüller H, Wegener G, Diebler G, Gellrich NC. Unilateral versus bilateral neck dissection in oral squamous cell carcinoma treated from 1984 to 2008: a single-center retrospective analysis

2. Olzowy B, Hillebrand M, Harréus U. Frequency of contralateral/bilateral cervical metastases of hypopharyngeal squamous cell carcinoma – a retrospective analysis of 204 patients after bilateral neck dissection

SCIENTIFIC PROGRAM Saturday, January 26, 2013

Panel discussion Eckel HE, Klagenfurt, Austria; Gullane P, Toronto, Canada; Lawson G, Yvoir, Belgium; Neff A, Marburg, Germany; Shah JP, New York, USA; Suen J, Little Rock, USA; Szyfter W, Poznan, Poland

10.30 am Coffee break

11.00 am Key note lecture 6 Chairpersons: Holsinger C, Houston, USA; Lang S, Essen, Germany

Neck dissection in advanced head and neck cancer Gullane P, Toronto, Canada

11.30 am Mini-Symposium 2 – Robotic surgery in head and neck cancer

Chairperson: Lang S, Essen, Germany; Olofsson J, Bergen, Norway

Free papers 1. Koh YW, Holsinger FC, Byeon HK, Hong HJ, Kim WS, Choi EC. Surgical feasibility and oncologic safety of robot-assisted neck dissection followed by transoral robotic surgery (TORS) in head and neck cancer

2. Koh YW, Kim WS, Park YM, Byeon HK, Chung HP, Hong HJ, Choi EC. Robot-assisted modified radical neck dissection via a modified face lift approach in clinical N+ head and neck cancer: a comparative study with the conventional transcervical neck dissection

3. Kim WS, Byeon HK, Park YM, Hong HJ, Kim SH, Choi HS, Choi EC, Koh YW. Comprehensive robot-assisted neck dissection via a transaxillary and retroauricular (“TARA”) approach in papillary thyroid cancer with cervical lymph node metastases: a comparative study with the conventional transcervical approach

12.00 TORS in oropharyngeal cancer Holsinger C, Houston, USA

12.20 pm TORS in laryngeal cancer Remacle M, Yvoir, Belgium

12.45 pm TORS – what can we expect for the future? Knecht R, Hamburg, Germany

SCIENTIFIC PROGRAM Saturday, January 26, 2013

01.00 pm Lunch

02.00 pm Panel 4 Lymph node metastases and radio(chemo)therapy Budach V, Berlin, Germany; Engenhart-Cabillic R, Marburg, Germany; Hambek M, Frankfurt, Germany; Lang S, Essen, Germany; Lippert BM, Heilbronn, Germany; Staar S, Bremen, Germany

03.00 pm Key note lecture 7 Chairpersons: Dietz A, Leipzig, Germany; Engenhart-Cabillic R, Marburg, Germany

Holistic view on radiochemotherapy Knecht R, Hamburg, Germany

03.20 pm Pulmonary metastasectomy in head and neck cancer – indications, techniques, and results Kirschbaum A, Marburg, Germany

03.30 pm Coffee break

04.00 pm Mini-Symposium 3 – Biotherapy in head and neck cancer

Chair: Dietz A, Leipzig, Germany

04.00 pm Efficacy and quality of survival Dietz A, Leipzig, Germany

04.20 pm Optimizing RT Treatment for patients with SCCHN Staar S, Bremen, Germany

04.40 pm Clinical perspectives in head and neck cancer Hambek M, Frankfurt, Germany

SCIENTIFIC PROGRAM Saturday, January 26, 2013

05.30 pm Free papers 5 Chairpersons: Lai Y, Guangzhou, China; Lawson G, Yvoir, Belgium

1. Meeuwis J, Witte BI, Hoekstra OS, Boellaard R, Leemans CR, de Bree R. The predictive value of 18 FDG SUV in the primary tumor and lymph node metastases for development of distant metastases in high risk head and neck cancer patients

2. Scheer M, Kreppel M, Drebber U, Semrau R, Zöller JE. Preoperative radiochemotherapy (RCT) in patients with N2 oral squamous cell carcinoma of the oral cavity

3. Pitak-Arnnop P, Pausch NC, Himpel M, Draenert FG, Dhanuthai K, Neff A. End-of-life care for head and neck tumour patients: Ethical viewpoints based on principalism

05.55 pm Poster Award

06.00 pm Panel 5 Lessons learned and future questions Folz BJ, Bad Lippspringe, Germany; Golusinski W, Poznan, Poland; Gullane P, Toronto, Canada; Olofsson J, Bergen, Norway; Shah JP, New York, USA; Werner JA, Marburg, Germany

07.00 pm End of the third day

SCIENTIFIC PROGRAM Sunday, January 27, 2013

Satellite Symposium Are arterio-venous malformations similar to malignant disease?

Chairmen: Negm, Hesham (Cairo, Egypt) Suen, James (Little Rock, USA) Werner, Jochen A. (Marburg, Germany)

09.00 am Introduction Werner JA, Marburg, Germany

09.15 am Key note lecture Classification of hemangiomas and vascular malformations Eivazi B, Marburg, Germany

09.45 am Key note lecture Treatment of arterio-venous malformations Suen J, Little Rock, USA

10.15 am Case discussions

11.30 am Panel – Immunology in vascular lesions Lang S, Essen, Germany; Whiteside T, Pittsburgh, USA; Mandapathil M, Marburg, Germany; Suen J, Little Rock, USA; Mandic R, Marburg, Germany

01.00 pm Adjourn

POSTERS

1. Albeyatti AD, Kwasnicki RM, Siau D, De Charpentier J. An unusual metastasis of a transglottic squamous cell carcinoma to the forearm: a case report

2. Bahgat YS. Laser cordectomy in glottic carcinoma

3. Beeck S, Schmidt A, Zhu L, Werner JA, Mandic R. Interrelation of EGFR and TrkB signalling and influence on cell adhesion molecules

4. Behrens B, Sproll KC, Möhlendick B, Alexander M, Baldus SE, Kübler NR, Knoefel WT, Brakenhoff RH, Stoecklein NH. Single cell analysis of head and neck squamous cell carcinoma (HNSCC) cell isolated from primary tumors and matched nodal metastases

5. Büntzel J, Danilkina G, Büntzel H. Elastic lymph taping in the head and neck region

6. Franke N, Hoch S, Vorwerk H, Werner JA, Teymoortash JA. Adjuvant radiotherapy in treatment of parotid metastases of squamous cell carcinoma of the skin

7. Günzel T. The value of PET compared to MRI in malignant head and neck tumors – a retrospective analysis of 120 cases

8. Gzirishvili L, Todua F, Mardaleishvili K, Kuchava V. Multi-slice computed tomography angiography in evaluation of vascular pattern of neck cancer metastasis and value of spread within neck structures

9. Hoch S, Katabi N, Werner JA, Teymoortash A. Have the patients with level IV metastases a higher risk for pulmonal metastases?

10. Wong G, Giddings C, Sandison A, Clarke P. Retrospective case series of sinonasal malignant melanoma: the Charing Cross Hospital experience

11. Kelly J, Mole G, Gibbins N. An unusual cause of hoarseness

12. Koh YW, Lee HS, Kim WS, Hong HJ, Choi EC. Robot-assisted supraomohyoid neck dissection via a modified face-lift or retroauricular approach in early- stage cN0 squamous cell carcinoma of the oral cavity: a comparative study with conventional technique

13. Kuchava V, Lomidze Z, Kristesashvili G, Gachechiladze A, Vashakidze M. Cancer or the upper lip with metastatic process in ipsilateral parotid gland and cervical lymph nodes – case report

14. Mandapathil M, Mandic R, Roeßler M, Moll R, Werner JA. Expression of ectonucleotidase and cyclooxygenase-2 in nodal metastasis of head and neck squamous cell carcinoma

POSTERS

15. Manganaris A, Karasmanis I. The application of the anterior cervical flap in major head and neck surgery

16. Peters TT, Senft A, Hoekstra OS, Castelijns JA, Witte BI, Leemans CR, de Bree R. Pretreatment screening on distant metastases and head and neck cancer patients: validation of risk factors and influence on survival

17. Papaspyrou G, Roeßler M, Werner JA, Sesterhenn AM. Transcervical extirpation of the submandibular gland - intraoperative and early postoperative complications

18. Peters TT, Castelijns JA, Ljumanovic R, Witte BI, Leemans CR, de Bree R. Diagnostic value of CT and MRI in the detection of paratracheal lymph node metastases

19. Pitak-Arnnop P, Bertolini J, Dhanuthai K, Hendricks J, Hemprich A, Neff A, Pausch NC. Intracranial extension of Schneiderian inverted papilloma: a case report and proposal of a treatment algorithm

20. Rossmann A, Mandic R, Heinis J, Höffken H, Bette M. Detection of metastasis by PET-CT analysis in the auricular VX2-carcinoma animal model system

21. Seitz D, Konnerth CG, Henschke F, Folz BJ. Metastasis to the base of the tongue

22. Wiegand S, Reuter I, Werner JA. The value of nodal ratio in patients with head and neck cancer

23. Wierzbicka M, Lezczynska M, Szyfter W, Mlodkowska A. The impact of prelaryngeal node metastases for early glottic cancer treatment results

24. Zhang Q, Ma L, Zhang X, Zhang N, Liu D, She C, Wang H. Radiofrequency coblation for treatment of vocal cords leukoplakia

25. Docter D, Gößwein D, Hahlbrock A, Stauber RH. Nanoparticle-based magnetic flow cytometry for the detection of disseminated head and neck cancer cells in biological fluids

LECTURERS, PANELISTS, AND CHAIRPERSONS

Al-Nawas B, Department of Maxillofacial Surgery, University of Main, Germany Brakenhoff R, Department of Otolaryngology, University of Amsterdam, The Netherlands Budach V, Department of Radiology, University of Berlin, Germany Buscombe J, Cambridge Cancer Center, Cambridge, United Kingdom Civantos F, Department of Otolaryngology, University of Miami, USA De Bree R, Department of Otolaryngology, University of Amsterdam, The Netherlands Dietz A, Department of Otolaryngology, University of Leipzig, Germany Eckel HE, Department of Otolaryngology, Klagenfurt, Austria Eivazi B, Department of Otolaryngology, University of Marburg, Germany Engenhart-Cabillic R, Department Radiotherapy, University of Marburg, Germany Folz BJ, Department of Otolaryngology, Bad Lippspringe, Germany Golusinski W, Department of Otolaryngology, Poznan University of Medical Sciences, Poland Gullane P, Department of Otolaryngology, University of Toronto, Canada Hambek M, Department of Otolaryngology, Frankfurt, Germany Holsinger C, Department of Otolaryngology, University of Houston, USA Hölzel D, Institute of Biometry and Epidemiology, University of Munich, Germany Iro H, Department of Otolaryngology, University of Erlangen, Germany Kirschbaum A, Department of Thoracic Surgery, University of Marburg, Germany Knecht R, Department of Otolaryngology, University of Hamburg, Germany Lai Y, Department of Otolaryngology, University of Guangzhou, China Lang S, Department of Otolaryngology, University of Essen, Germany Lawson G, Department of Otolaryngology, University of Yvoir, Belgium Lippert BM, Department of Otolaryngology, Heilbronn, Germany Mandapathil M, Department of Otolaryngology, University of Marburg, Germany Mandic R, Department of Otolaryngology, University of Marburg, Germany McGurk M, Department of Otolaryngology, London, United Kingdom Neff A, Department of Maxillofacial Surgery, University of Marburg, Germany Negm H, Department of Otolaryngology, University of Cairo, Egypt Olofsson J, Department of Otolaryngology, University of Bergen, Norway Pepe G, Department of Otolaryngology, University of Corrientes, Argentina Reininger C, Navidea Company, Dublin, USA Remacle M, Department of Otolaryngology, University of Yvoir, Belgium

LECTURERS, PANELISTS, AND CHAIRPERSONS

Roeßler M, Institute of Pathology, University of Marburg, Germany Shah JP, Department of Otolaryngology, Memorial Sloan Kettering Cancer Center, New York, USA Staar S, Department of Radiotherapy, Bremen, Germany Stoeckli S, Department of Otolaryngology, University of St. Gallen, Switzerland Suen J, Department of Otolaryngology, University of Arkansas, Little Rock, USA Szyfter K, Department of Human Genetics, Poznan University of Medical Sciences, Poland Szyfter W, Department of Otolaryngology, Poznan University of Medical Sciences, Poland Teymoortash A, Department of Otolaryngology, University of Marburg, Germany Werner JA, Department of Otolaryngology, University of Marburg, Germany Whiteside T, Department of Otolaryngology, University of Pittsburgh, USA Wiegand S, Department of Otolaryngology, University of Marburg, Germany Wittekind C, Department of Radiology, University of Leipzig, Germany Wollenberg B, Department of Otolaryngology, University of Lübeck, Germany

INDUSTRIAL EXHIBITORS AND DONATORS

Symposium Supporters

Biomedical Technology, Otto-Schott-Str. 15a, 07745 Jena, Germany ev3 GmbH, Siegfriedstr. 28, 53179 Bonn, Germany Fahl Medizintechnik Vertrieb GmbH, August-Horch-Str. 4a, 51149 Köln, Germany Intuitive Surgical Sarl, Chemin des Mûriers 1, 1170 Aubonne, Switzerland J. Morita Europe GmbH, Justus-von-Liebig-Str. 27a, 63128 Dietzenbach, Germany Karl Storz GmbH & Co. KG, Mittelstr. 8, 78532 Tuttlingen, Germany Lumenis GmbH, Heinrich-Hertz-Str. 3, 63303 Dreieich, Germany Marburger Epithetik Studio, Im Stetefeld 19, 35094 Lahntal-Caldern, Germany Medtronic GmbH, Earl-Brakken-Platz 1, 40670 Meerbusch, Germany Merck Serono GmbH, Alsfelder Str. 17, 64289 Darmstadt, Germany Navidea Biopharmaceuticals, 425 Metro Place North Suite 450, Dublin, OH 43017 Olympus Europa Holding GmbH, Wendenstr. 14-18, 20097 Hamburg, Germany Serag-Wiessner KG, Zum Kugelfang 8-12, 95119 Naila, Germany Servona GmbH, Biberweg 24-26, 53842 Troisdorf, Germany Spiggle & Theis Medizintechnik GmbH, Diepenbroich 15, 51491 Overath, Germany SurgicEye GmbH, Friedenstr. 18a, 81671 München, Germany

NOTES

IMPRESSUM

Herausgeber und verantwortlich für den redaktionellen Inhalt: Dept. of Otolaryngology, Head and Neck Surgery, University of Marburg, Baldingerstr., D-35041 Marburg

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