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Working Together to Treat Recurrent Prostate Cancer

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Working Together to Treat Recurrent Prostate Cancer DonorDollars at Work Spring 2015 DonorDollars at Work DonorDollars at Work Fall 2016 NEW CLINICAL EXPANSION OFFERS a place of hope The new Chemotherapy Infusion Center in the Scott Bieler Clinical Sciences Center offers a bright, sunny atmosphere and a view of Buffalo’s skyline. Roswell Park Cancer Institute recently opened its first clinical Since the campaign began in 2014, an astonishing $32.7 million was expansion in nearly two decades, and it was made possible by a raised through philanthropic gifts to build the facility – more than community of people who believe in the Institute’s mission. two-thirds of the $50.5 million needed to complete the project. Additionally, Sen. Charles Schumer, Rep. Brian Higgins and Buffalo In May, the Scott Bieler Clinical Sciences Center (CSC) opened on Mayor Byron Brown all assisted in securing $6.3 million in New Roswell Park’s campus, featuring 11 stories and 142,000 square feet Market Tax Credits. of space for patients to receive comprehensive care from prevention to survivorship. The combined generosity of each and every donor, no matter the gift amount, will mean enhanced specialized care and increased To make this healing hub a reality, it took a tremendous number of innovation in treatment for countless Roswell Park patients as we aim donors and advocates with a passion for helping people not just to meet the growing demand for comprehensive cancer care. survive, but thrive in the face of cancer. The Clinical Sciences Center was named in honor of Scott Bieler, More than 500 individuals, corporations, foundations, organizations president of West Herr Automotive Group, for making a historic gift and Roswell Park faculty and staff contributed to the Making Room commitment to the Institute’s Priority Endowment Fund. to Save Lives campaign, which was co-chaired by Donna Gioia and Scott Bieler. (continued on back page) Fifteen donors, each contributing $1 million or more, also helped make the center a reality. Among this Circle of 15 was The Ride For Roswell which contributed a gift comprised of donations from What’s Inside hundreds of thousands of its riders and supporters from across • New Clinical Expansion Offers a Place of Hope p1 Western New York and beyond. The other donors who created the • Working Together to Treat Prostate Cancer p2 Circle of 15 were the Scott R. Bieler Foundation, Bill and Nancy Gacioch and Family, the Garman Family, Richard and Anne Gioia • Funding for Fertility Preservation Options p3 and Ambassador Anthony and Donna Gioia, the Hawk Family, the • Roswell’s Brightest Working Together p4 - 5 Jeremy Jacobs Family, The Patrick P. Lee Foundation, Stanford and Judith Lipsey, Al and Kit Maroone, The Estate of Lawrence Minet, PhD, • Roswell Park’s Quilts p6 New Era Cap, The John R. Oishei Foundation, The Ralph C. Wilson Jr. Foundation and an anonymous donor. • Craig Wittmann’s Empire State Ride p7 TEAM SCIENCE The Team Irwin Gelman, PhD, Professor of Oncology and Director of Research Integration at Roswell Park David Goodrich, PhD, Department of Pharmacology and Therapeutics Dean Tang, PhD, Chair of the Department of Pharmacology and Therapeutics Leigh Ellis, PhD, Department of Pharmacology and Therapeutics Shahriar Koochekpour, MD, PhD, Department of Cancer Genetics, Medicine and Urology John Krolewski, MD, PhD, Interim Chair of the Department of Cancer Genetics Kent Nastiuk, PhD, Department of Cancer Genetics Irwin Gelman, PhD, is leading a team toward more effective treatments for recurrent prostate cancer. WORKING TOGETHER TO TREAT RECURRENT PROSTATE CANCER Thanks to advancements in prostate cancer screening and treatments, it’s becoming increasingly rare for a patient to succumb to his initial prostate cancer. Recurrent prostate cancer, however, can be highly fatal because it no longer responds to standard therapies and tends to recur in other areas of the body. Irwin Gelman, PhD, Professor of Oncology and Director of Research Integration at Roswell Park, is investigating how to better treat recurrent prostate cancers and improve patient outcomes. The task is not an easy one and the urgency is great, but he is not tackling this research alone. He is just one of several Roswell Park specialists working on this research project to explore more effective treatments for recurrent prostate cancers. According to Dr. Gelman, this Team Science The generosity of Roswell Park supporters provided the seed funding approach works much like a sports team – each team member for the initial research efforts for this project. Now, the team has contributes his or her specialties and expertise to the program in collected the data they need to apply for a national grant to begin order to achieve a positive outcome. clinical trials and bring new treatments to patients who can hopefully “The bottom line is that it helps advance research tremendously benefit from them. If it weren’t for donor support, this possibility would because you have more systems, more minds,” said Dr. Gelman. have been entirely out of reach. “The point of seed money from the Alliance Foundation is to put that The team has already completed preliminary studies on the pathways seed in the ground, which you then take the fruit of and use to apply to that drive the recurrence of this cancer, and are now looking to move larger organizations like the National Institute of Health for established one step closer to a realized treatment. This promising research grants,” said Dr. Gelman. has the potential to save lives, but without the support of donors like you, the first steps would have gone un-funded This is just one of several Team Science research programs underway and this team of specialists may have never had the chance at Roswell Park, and with continued donor support more promising to work together. ideas can be given the chance to flourish. 2 Donor Dollars at Work 2 Donor Dollars at Work Funding for Fertility Preservation Increases Patients’ Options Those who undergo chemotherapy or radiation for cancer can face The decision was made to preserve sperm for the future, as Jacob a number of challenges and long-term side effects. Among those was told he would have between a 10 and 15 percent chance of possible obstacles is the potential for diminished fertility for both conceiving naturally. men and women. Jacob says knowing that this assistance is available to those who need For many patients with cancer, particularly teens and young adults, it most can help alleviate some of the stress faced by young patients. the ability to have a child one day is of paramount importance. “The cost of fertility preservation can be overwhelming, Steps can be taken prior to treatment to increase the chances especially on top of medical expenses,” he said. “It’s not for conception in the future, such as cryopreservation of sperm supposed to be a stressful thing, having a baby, it’s supposed for men, and of eggs and embryos for women. These treatments, to be a happy thing, especially after you’ve beaten cancer.” however, can become cost prohibitive. Jacob and his wife, Lorrina, were recently able to beat the odds and With the help of generous Roswell Park donors, we can put these conceive naturally, but for him, fertility planning still had a major impact options within reach for more of our patients than ever before. on his wellbeing. Thanks to supporters like you, Roswell Park is able to offer financial assistance to individuals of reproductive age who During the time of treatment, Jacob, like many patients, had many otherwise could not afford these preservation services. pressing issues to face. The peace of mind brought about by having a future plan should natural conception not be an option was a burden “Thanks to our donors, many patients realize that preserving their lifted during that challenging time. “I am still so thankful, just to have fertility is a realistic option,” said Lynda Beaupin, MD, Director of the always known that I had options,” he said. Adolescent and Young Adults Cancer Program. While many fertility preservation services are offered off-site through referrals, Roswell Park has recently made an Onco-Fertility Program available to our patients as a part of an expanding Survivorship Program. The Onco-Fertility Program addresses the effects cancer treatment has on sexuality and fertility from identifying risks, to acting as a liaison between a patient’s primary oncology team and outside fertility services to which a patient could be referred. Jacob Madonia was diagnosed with synovial sarcoma in his teens and understands just how important having fertility preservation options available can be, both for the future as well as a patient’s present ease of mind. “You don’t think about planning a family too much when you’re 19 years old, so it was not at the forefront of my mind,” he said. That was what he thought as he faced his initial diagnosis and treatment, but when he had a recurrence five years later and was engaged Jacob Madonia and his wife, Lorrina, plan to welcome their first child this fall. to his now wife, the situation was a bit different. RoswellPark.org/Giving | 716.845.4444 3 Roswell Park’s Brightest Work Together for Improved Futures Cancer, in its many forms, presents a host of complicated challenges to those who are seeking to find treatments and cures. Such complex issues are often best solved by the meeting of many minds in different areas of specialty. Such scientists and clinicians need a venue in which they can utilize one another’s knowledge and skills in order to create solutions. At Roswell Park, doctors and scientists combine their While the research goals of each group are different, they clinical and scientific expertise to identify the most pressing hold in common the desire to create better outcomes for all research needs for specific disease sites, such as breast, those who walk through the doors of Roswell Park.
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