International Journal of Environmental Research and Public Health Review Management of Endocrinopathies in Pregnancy: A Review of Current Evidence Daniela Calina 1,† , Anca Oana Docea 2,*,†, Kirill Sergeyevich Golokhvast 3,†, Stavros Sifakis 4, Aristides Tsatsakis 5 and Antonis Makrigiannakis 6 1 Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania;
[email protected] 2 Department of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania 3 Scientific Education Center of Nanotechnology, Far Eastern Federal University, Vladivostok 690950, Russia;
[email protected] 4 Department of Obstetrics and Gynecology, Mitera Maternity Hospital, 71110 Heraklion, Crete, Greece;
[email protected] 5 Department of Forensic Sciences and Toxicology, Faculty of Medicine, University of Crete, 71110 Heraklion, Crete, Greece;
[email protected] 6 Department of Obstetrics and Gynecology, Medical School, University of Crete, 71110 Heraklion, Crete, Greece;
[email protected] * Correspondence:
[email protected] † These authors contributed equally to this work. Received: 28 January 2019; Accepted: 27 February 2019; Published: 4 March 2019 Abstract: Pregnancy in women with associated endocrine conditions is a therapeutic challenge for clinicians. These disorders may be common, such us thyroid disorders and diabetes, or rare, including adrenal and parathyroid disease and pituitary dysfunction. With the development of assisted reproductive techniques, the number of pregnancies with these conditions has increased. It is necessary to recognize symptoms and correct diagnosis for a proper pharmacotherapeutic management in order to avoid adverse side effects both in mother and fetus. This review summarizes the pharmacotherapy of these clinical situations in order to reduce maternal and fetal morbidity.