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16667 Rules and Regulations Federal Register Vol. 86, No. 60 Wednesday, March 31, 2021 This section of the FEDERAL REGISTER isomers, esters, ethers, salts, and salts of opiates crotonyl fentanyl, contains regulatory documents having general isomers, esters, and ethers, permanently ketobemidone, para-fluorofentanyl, and applicability and legal effect, most of which in schedule I of the Controlled phenampromide (i.e., (b)(22), (40), (56), are keyed to and codified in the Code of Substances Act, specifically to the and (59)). In addition, the final rule Federal Regulations, which is published under opiates list under DEA regulations. The incorrectly added valeryl fentanyl as a 50 titles pursuant to 44 U.S.C. 1510. published document assigned incorrect new paragraph (b)(75) instead of (b)(76). The Code of Federal Regulations is sold by paragraph numbers to all five This document updates the numbering the Superintendent of Documents. substances, and inadvertently removed of all listed opiates in paragraph (b), and four other substances from the listed specifically corrects the paragraph opiates. numbers for cyclopentyl fentanyl, DEPARTMENT OF JUSTICE DATES: Effective date: March 31, 2021. isobutyryl fentanyl, para- chloroisobutyryl fentanyl, para- Drug Enforcement Administration FOR FURTHER INFORMATION CONTACT: methoxybutyryl fentanyl, and valeryl Terrence L. Boos, Drug and Chemical fentanyl, and reassigns paragraph 21 CFR Part 1308 Evaluation Section, Diversion Control numbers for crotonyl fentanyl, Division, Drug Enforcement [Docket No. DEA–565] ketobemidone, para-fluorofentanyl, and Administration; Telephone: (571) 362– phenampromide. It bears emphasis that 3249. Schedules of Controlled Substances: DEA still considers the four substances Placement of cyclopentyl fentanyl, SUPPLEMENTARY INFORMATION: On (crotonyl fentanyl, ketobemidone, para- isobutyryl fentanyl, para- November 25, 2020, the Drug fluorofentanyl, and phenampromide) to chloroisobutyryl fentanyl, para- Enforcement Administration (DEA) have been schedule I substances during methoxybutyryl fentanyl, and valeryl permanently placed five fentanyl- the time period from the issuance of the fentanyl in Schedule I; Correction related substances (cyclopentyl fentanyl November 25, 2020, final rule to this (N-(1-phenethylpiperidin-4-yl)-N- AGENCY: Drug Enforcement correction, despite these inadvertent Administration, Department of Justice. phenylcyclopentanecarboxamide), numbering errors.1 isobutyryl fentanyl (N-(1- ACTION: Final rule; correcting phenethylpiperidin-4-yl)-N- List of Subjects in 21 CFR Part 1308 amendment. phenylisobutyramide), para- Administrative practice and SUMMARY: The Drug Enforcement chloroisobutyryl fentanyl (N-(4- procedure, Drug traffic control, Administration is correcting a final rule chlorophenyl)-N-(1-phenethylpiperidin- Reporting and recordkeeping that appeared in the Federal Register on 4-yl)isobutyramide), para- requirements. methoxybutyryl fentanyl (N-(4- November 25, 2020. The document For the reasons set out above, 21 CFR issued an action placing five fentanyl- methoxyphenyl)-N-(1- part 1308 is amended as follows: related substances (cyclopentyl fentanyl phenethylpiperidin-4-yl)butyramide), (N-(1-phenethylpiperidin-4-yl)-N- and valeryl fentanyl (N-(1- PART 1308—SCHEDULES OF phenylcyclopentanecarboxamide), phenethylpiperidin-4-yl)-N- CONTROLLED SUBSTANCES isobutyryl fentanyl (N-(1- phenylpentanamide) in schedule I of the phenethylpiperidin-4-yl)-N- Controlled Substances Act (CSA), ■ 1. The authority citation for 21 CFR phenylisobutyramide), para- specifically to the opiates list under 21 part 1308 continues to read as follows: chloroisobutyryl fentanyl (N-(4- CFR 1308.11(b). 85 FR 75231. The final chlorophenyl)-N-(1-phenethylpiperidin- rule incorrectly assigned paragraph Authority: 21 U.S.C. 811, 812, 871(b), 956(b), unless otherwise noted. 4-yl)isobutyramide), para- numbers 22, 40, 56, and 59 under methoxybutyryl fentanyl (N-(4- paragraph (b) to cyclopentyl fentanyl, ■ 2. In § 1308.11(b), revise the table to methoxyphenyl)-N-(1- isobutyryl fentanyl, para- read as follows: phenethylpiperidin-4-yl)butyramide), chloroisobutyryl fentanyl, and para- and valeryl fentanyl (N-(1- methoxybutyryl fentanyl, respectively, § 1308.11 Schedule I. phenethylpiperidin-4-yl)-N- overriding previously assigned * * * * * phenylpentanamide), including their paragraph numbers for four listed (b) * * * (1) Acetyl-alpha-methylfentanyl (N-[1-(1-methyl-2-phenethyl)-4-piperidinyl]-N-phenylacetamide) ................................................... 9815 (2) Acetylmethadol ..................................................................................................................................................................................... 9601 (3) Acetyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide) ............................................................................................... 9821 (4) Acryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylacrylamide; also known as acryloylfentanyl) ......................................... 9811 (5) AH–7921 (3,4-dichloro-N-[(1-dimethylamino)cyclohexylmethyl]benzamide) .................................................................................. 9551 (6) Allylprodine .......................................................................................................................................................................................... 9602 (7) Alphacetylmethadol (except levo-alphacetylmethadol also known as levo-alpha-acetylmethadol, levomethadyl acetate, or LAAM) ..................................................................................................................................................................................................... 9603 (8) Alphameprodine ................................................................................................................................................................................... 9604 (9) Alphamethadol ...................................................................................................................................................................................... 9605 1 Under the CSA, a controlled substance may only U.S.C. 811 and published in the Federal Register. status of these four substances was never altered by be removed from the schedules, or transferred to DEA took no such action with respect to crotonyl the final rule that appeared in the Federal Register another schedule, where DEA expressly does so by fentanyl, ketobemidone, para-fluorofentanyl, and on November 25, 2020. a scheduling action issued in accordance with 21 phenampromide. Accordingly, the scheduling VerDate Sep<11>2014 15:38 Mar 30, 2021 Jkt 253001 PO 00000 Frm 00001 Fmt 4700 Sfmt 4700 E:\FR\FM\31MRR1.SGM 31MRR1 jbell on DSKJLSW7X2PROD with RULES 16668 Federal Register / Vol. 86, No. 60 / Wednesday, March 31, 2021 / Rules and Regulations (10) alpha-Methylfentanyl (N-[1-(alpha-methyl-beta-phenyl)ethyl-4-piperidyl]propionanilide; 1-(1-methyl-2-phenylethyl)-4-(N- propanilido)piperidine) .......................................................................................................................................................................... 9814 (11) alpha-Methylthiofentanyl (N-[1-methyl-2-(2-thienyl)ethyl-4-piperidinyl]-N-phenylpropanamide) .............................................. 9832 (12) Benzethidine ....................................................................................................................................................................................... 9606 (13) Betacetylmethadol ............................................................................................................................................................................... 9607 (14) beta-Hydroxyfentanyl (N-[1-(2-hydroxy-2-phenethyl)-4-piperidinyl]-N-phenylpropanamide) ...................................................... 9830 (15) beta-Hydroxy-3-methylfentanyl (N-[1-(2-hydroxy-2-phenylethyl)-3-methyl-4-piperidinyl]-N-phenylpropanamide) .................. 9831 (16) beta-Hydroxythiofentanyl (N-[1-[2-hydroxy-2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropionamide) ............................. 9836 (17) Betameprodine .................................................................................................................................................................................... 9608 (18) Betamethadol ....................................................................................................................................................................................... 9609 (19) Betaprodine ......................................................................................................................................................................................... 9611 (20) Butyryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylbutyramide) ......................................................................................... 9822 (21) Clonitazene .......................................................................................................................................................................................... 9612 (22) Crotonyl fentanyl ((E)-N-(1-phenethylpiperidin-4-yl)-N-phenylbut-2-enamide) ............................................................................. 9844 (23) Cyclopentyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylcyclopentanecarboxamide) .........................................................
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