Fall 2020

Bringing CNS Members Together to Make Children’s Lives Better

Honoring our Founder Kenneth Swaiman, MD

TOGETHER•APART virtual OCTOBER 12-23,2020 2020

Sharing Knowledge • Sowing Friendships • Spreading Hope TOGETHER•APART virtual OCTOBER 12-23,2020 2020

ICNA • CNS ICNA • CNS

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

Sharing Knowledge Sowing Friendships • Spreading Hope CONTENTS FALL 2020

CONNECTING WITH COLLEAGUES 6 4 LETTER FROM THE PRESIDENT

6 IN MEMORIAM – KENNETH FRED SWAIMAN, MD

10 LETTER FROM THE EDITOR

12 2020 CNS AWARD RECIPIENTS

19 ICNA•CNS | TOGETHER•APART VIRTUAL 2020 22 YOU ARE INVITED! 19 24 10 THINGS TO KNOW BEFORE YOU GO 30 SCHEDULE 79 SCHEDULE AT A GLANCE 85 REGISTRATION 86 INDUSTRY-SPONSORED SEMINARS & PRODUCT THEATERS 89 SPONSOR/EXHIBITORS

CONNECTING WITH PARTNERS

94 PROFESSORS OF CHILD NEUROLOGY

96 PROGRAM COORDINATORS OF CHILD NEUROLOGY

97 ASSOCIATION OF CHILD NEUROLOGY NURSES 98 ACNN AWARD RECIPIENTS Child Neurology Society 102 VIRTUAL+VITAL ACNN CONFERENCE SCHEDULE 1000 West Cty Rd. E, Suite 290 St. Paul, MN 55126 Tel: 651/486-9447 104 CHILD NEUROLOGY FOUNDATION Fax: 651/486-9436 Email: nationaloffice@ childneurologysociety.org www.childneurologysociety.org CONNECTING WITH THE FUTURE Editor: Daniel Bonthius, MD, PhD Managing Editor: Roger Larson, CAE 107 PERSONNEL REGISTRY Published Quarterly

Child Neurology Society | Fall 2020 3 CONNECTING WITH COLLEAGUES Letter from the President

“We have come a long way together...” Phillip L. Pearl, MD

ur annual rite-of-fall pilgrimage to the CNS meeting feels very “Fall arrived at last. O different this year, as has the rest of life. But we have come a long Order returns to the universe. way together. In the stillness of the early stages of COVID-19, as society A new school year, autumn grounded to a veritable halt, the CNS sprang into action. Early steps focused on ethical challenges, especially the allocation of limited resources and leaves, the CNS meeting! importance of not squandering them or delivering disproportionate care, We’ve come so far and our Ethics committee was at the forefront (Graf et al 2020). We pivoted since last year in Charlotte!” to assembling a toolkit for telemedicine, and later provided resources to help gradually and safely reopen practices, with special thanks to our Telemedicine task force and Practice Committee. We were compelled to “Come so far?! This bleak recommend new guidelines for the evaluation and treatment of one of our year has been a mess. distinct populations, children with infantile spasms, and again turned to the The worst pandemic in a century. Practice Committee, which collaborated closely with the Pediatric Epilepsy Research Consortium (Grinspan et al 2020a, b). The Research Committee And we haven’t gone anywhere. focused on prioritizing research goals at the call of NINDS, with revisions I’m doing this meeting predicated upon the pandemic (Bonkowsky et al, in submission). And from home!” as social unrest unfolded in some of our country’s darkest moments, we responded with genuineness and resolve (Pearl et al 2020), expanding our original pledge in October 2019 to appoint a diversity officer to forming a “Yes...I hear you...” task force commissioned to explore and design a Diversity and Leadership Development Program that would complement and build on programming

4 Child Neurology Society | Fall 2020 offered by the AAN and AES, among others. These are just perspective of two board members rotating off, without a few selected areas that have compelled focused attention whom the momentum and accomplishments of this past and action within the CNS throughout the year. year would not have been possible: Past-President Jonathan Mink and Councillor for the West Mark Wainwright. As we gather together for this International Child Neurology Conference, however virtual, I would like to point out some We are eagerly looking forward to gathering together special features and events of interest to all. Jon Mink and next fall for our 50th/Golden Anniversary meeting the Scientific Program Planning Committee have assembled in Boston. We will pay homage to our first fifty years a breathtaking array of sessions covering an astonishing while also looking forward. To that end, Steve Ashwal is breadth and depth of topics in pediatric neurology. We working feverishly on a second edition of the Founders of continue to feature robust ancillary programming, including Child Neurology book first published in 1989; this will be the Neurobiology of Disease in Childhood Symposium expanded into the Founding, Evolution, and Development organized by Bernie Maria, the Child Neurology Foundation of Child Neurology with updates covering seminal figures symposium which this year will cover the diagnostic odyssey shaping the 2nd half of 20th Century. The very recent loss in genetic testing, and the 5th Annual Jack Pellock Residents of CNS Founder and First President Ken Swaiman has led Seminar on Epilepsy for senior child neurology trainees. We to many members of the society sending Steve and Phyllis are grateful for the support provided the Pellock Seminar Sher, CNS member and Ken’s widow, stories about their through a five-year grant from the Pediatric Epilepsy Research contact with Dr. Swaiman as a colleague, mentor, teacher, Foundation (PERF). As the host for this year’s international and friend. If you would like to send a personal story, congress, we are pleased to offer a special education and please do so to either Phyllis ([email protected]) or Steve entertainment series on American Creativity, Ingenuity and ([email protected]); they would appreciate your thoughts. Diversity; for more on that, see pages 28. And in time we will roll out the exciting new ventures in My fervent hope is that you sample the many offerings place to engage our membership, recruit trainees and made available during this two week virtual conference junior members, reinvigorate careers at all levels, and bring thanks to the extraordinary efforts by our national office staff. the best of pediatric neuroscience to all of us. Special thanks are owed to Executive Director Roger Larson, Associate Director Sue Hussman, the ever friendly, ever- Enjoy the conference! reliable Kathy Pavel and Emily McConnell, and this year’s contracted videographer responsible for capturing nearly 300 Phillip L. Pearl, M.D. symposia presentations, Richard Kearney . President, Child Neurology Society Director of Epilepsy and Clinical Neurophysiology Beyond this year’s challenging but promising conference, William G. Lennox Chair, Department of Neurology other activities continue. We successfully renegotiated Boston Children’s Hospital a contract to continue offering the Annals of Neurology Professor of Neurology, Harvard Medical School as our societal journal in partnership with the American Music and Health Institute, Berklee College of Music Neurological Association, with online access expanded to include CNS members of all categories (only Active Members Citations previously received the print journal). The ANA has been a strong partner in publishing content that is very germane to Graf WD, Epstein LG, Pearl PL: Practical Bioethics during child neurology and developmental neuroscience. A recent the Exceptional Circumstances of a Pandemic. Pediatr search has been initiated for a new rotation for the Editor- Neurol 2020; 108:3-4. in-Chief position, and interested persons are encouraged to Grinspan ZM, Mytinger JR, Baumer FM, et al. Management inquire: https://myana.org/publications/annals-neurology- of Infantile Spasms During the COVID-19 Pandemic. J editor-chief-job-description. Child Neurol 2020a; 35:828-34.

CNS committees are already setting ambitious agendas for Grinspan ZM, Mytinger JR, Baumer FM, et al. Crisis the next year as is the CNS Executive Committee with four Standard of Care: Management of Infantile Spasms during newly elected officers: Bruce Cohen – President Elect, Lori COVID-19. Ann Neurol 2020b; 22:215-7. Jordan – Secretary-Treasurer, and new Councillors Audrey Pearl PL, Mink JW, Cohen BH, et al. The President, Past Brumback and Sonia Partap. While Bruce and Lori move up President, Executive Director, and the Board of the Child from previous positions on the Board as Secretary-treasurer Neurology Society Denounce Racism and Inequality. Ann and Councillor for the South, we will miss the passion and Neurol 2020; 22:209-10.

Child Neurology Society | Fall 2020 5 IN MEMORIAM

Kenneth Fred Swaiman, MD November 19, 1931 - September 18, 2020

en Swaiman was a visionary who has played a in St. Paul, and moved to Minneapolis. Ken attended the K universally recognized, pivotal and remarkable role University of Minnesota, earning degrees in Liberal Arts (Magna in the development of child neurology. He initiated the Cum Laude, 1952), Science (1953), and Medicine (1955) and founding of the Child Neurology Society, the Professors of then joined a rotating internship at the Minneapolis General Child Neurology and the Child Neurology Foundation, and Hospital (1955-56), followed by a Pediatric residency and Chief the publication of what is regarded as the primary textbook residency at the University of Minnesota Hospitals (1956-58). in the field, Pediatric Neurology: Principles and Practice. He This was followed by two years as Chief of Pediatrics at a US began the journal, Pediatric Neurology, one of the major Army Hospital (Ft. McPherson, GA). He returned to Minnesota pediatric neurological journals and served as its editor from where he was an NIH-sponsored ‘Special Fellow in Pediatric 1984-2012. For these and many other accomplishments, Neurology’ (1960-63) under the mentorship of Dr. A.B. Baker, Ken was honored by the Child Neurology Society at the one of the founders of the American Academy of Neurology 2017 Legacy Reception. (1948). Ken received board certifications from the American Board of Pediatrics (1960), the American Board of Psychiatry Ken, although born in St. Paul (1931), was raised in and Neurology (1966) and the American Board of Psychiatry Minneapolis, Minnesota. His Lithuanian parents, before and Neurology, with Special Competence in Child Neurology meeting, separately immigrated to the United States, met (1969).

6 Child Neurology Society | Fall 2020 First CNS Executive Committee: Standing (l-r): John Menkes, Isabelle Rapin, Gerald Fenichel, Kenneth Swaiman, Richard Allen, Manuel Gomez, James Schwartz

Ken joined the Pediatric and the Neurology faculties at Minnesota (1963) and within a decade became a full Professor in both departments. He was Director of the Pediatric Neurology Training Program and Director of Pediatric Neurology (1972), serving in those capacities until 1998. During his career, Ken belonged to 20 professional organizations. He engaged in basic science research: GABA and phenylalanine metabolism, metabolic abnormalities in pediatric neuromuscular conditions, the effects of malnutrition on the developing brain, and clinical disorders, including acid maltase deficiency, sea blue histiocytosis and the effects of iron and other metals on cerebral energetics. Ken’s interest in clinical teaching and research investigation, and transmitting this information to the trainees in his “Minnesota Twins.” Ken Swaiman and Bruce Berg: both 1) program and worldwide, was always in the forefront of native-born Minnesotans, 2) proud alumni of the University his thoughts. He held leadership positions in key child of Minnesota (undergraduate and medical school), 3) neurology organizations, including the Child Neurology Presidents of the Child Neurology Society, 4) Presidents of Society (CNS, First President 1972-1973), International Child the Professors of Child Neurology, and 5) recipients of the Neurology Association (Executive Committee 1970-1979), CNS Hower Award. Professors of Child Neurology (PCN, First President 1978-80) and the Child Neurology Foundation (CNF, First President 2000-2003). Ken was also on many National Institutes of Health Study Sections and has shared his knowledge as a the CNS (1996); and the American Academy of Neurology visiting professor giving over 50 special lectures throughout Lifetime Achievement Award for Neurologic Education the United States and in many countries worldwide. (2005).

Trainees and Awards. Ken served on 15 editorial During his tenure at Minnesota, Ken trained over 80 child boards of major scientific journals. He also served as a neurologists and he felt that contact with his residents was board examiner for the American Board of Psychiatry and one of his prime motivating forces for beginning all of the Neurology. He has received numerous awards, with the organizations that he started. He felt that the role of teacher three most prestigious being the Hower award (1981), the and mentor was the most important responsibility that a highest award given by the CNS to an individual who is faculty member can have. His trainees came from all over highly regarded as an outstanding teacher and scholar, and the world and went on to provide continuing education in additionally, has given a high level of service to the CNS; the U.S. and in their home countries. the Founder’s Award at the 25th anniversary meeting of continued on next page

Child Neurology Society | Fall 2020 7 (CNS, ACGME and ABPN). Ken was a tireless advocate for improving the quality of pediatric neurological education, the advancement of the field, and the means to increase the knowledge and capability of pediatric neurologists.

Child Neurology Foundation. Ken founded the CNF in 1999, recognizing the need to support the outreach of child neurologists and support of families and children with neurological disorders. He was the CNF’s first President and he was instrumental in securing the resources to start the organization’s Researcher in Training and Scientific Awards. Such was the trust in the future of the Foundation that significant industry support was obtained through Ken’s and Roy Elterman’s efforts. More recently, the CNF redirected its efforts to focus on the needs of families and Longtime colleague, friend, and fellow past-CNS President children, and it conducts unique symposia at the annual Paul Rosman presented Ken with a “supplement” to the CNS meeting. “Founders Award” given to him at the 25th Anniversary Meeting of the CNS. Pediatric Neurology: Principles and Practice. The first textbook solely devoted to the entire field of Child Neurology appeared in 1845 (Ludwig Mauthner). Over Child Neurology Society. The first Accreditation Council the ensuing century, additional monographs were written for Graduate Medical Education (ACGME) specialty board by Bernard Sachs (1895), James Taylor (1905), Martin devoted to individuals with neurological and psychiatric Theimich and Julius Zappert (1910), Ludwig Bruns (1912), disorders, the American Board of Psychiatry and Neurology George Peritz (1912), Bronson Crothers (1926), and Frank (ABPN), was established in 1934. Another 34 years elapsed Ford (1937). For a variety of reasons, comprehensive before Child Neurology was recognized as a distinct texts devoted to the field did not appear until that of neurology subspecialty (American Board of Psychiatry and John Menkes (1974), the first edition of the book by Ken Neurology, with Special Competence in Child Neurology, Swaiman and Frank Wright (1975) and the textbook by 1968). Having long recognized the uniqueness of child Jean Aicardi (1992). The book, “The Practice of Pediatric neurology, Ken gathered together a small group of senior Neurology,” edited by Ken and Frank Wright and the Midwest pediatric neurologists in 1971 and the following subsequent 1982 edition were internationally acclaimed. year, he founded the CNS (1972), holding the first meeting Ken then became sole editor of the next edition (1989) at the University of Michigan. There, the Society was when the title changed to “Pediatric Neurology: Principles incorporated, by-laws were created, an Executive Board was formed, and plans were made to hire administrative staff. The formation of the CNS was a major force in the expansion of Pediatric Neurology training programs, and many more medical students and residents decided to pursue a career in pediatric neurology.

Professors of Child Neurology. The Association of University Professors of Neurology (AUPN), one the principal organizations involved in the training of neurologists, held its first meeting in 1968 to address training, legislative, workforce and research funding issues and to serve as a liaison with many organizations. Realizing the importance of having a parallel organization for academic child neurologists, Ken founded the PCN with the help of Bruce Berg (1978), with Ken serving as its first President. The PCN meets at the CNS annual meeting and Ken and Ray Chun: longtime friends, tennis partners and serves many roles including support of training programs, members of the gathering in LaCrosse, WI of midwestern program directors, coordinators and residents, as well as child neurologists who drafted plans for a national serving as the interface with multiple other organizations organization of child neurologists.

8 Child Neurology Society | Fall 2020 Photo Credits: Suzanne Shaff Photography

More than any other modern-day neurologist, Kenneth Swaiman has led the way in establishing the field of child neurology. He has served as the most lustrous academic beacon in the CNS. To hundreds of academicians, he has shown the way in patient care, teaching, research and scholarship and, in that way, has bettered the lives of tens of thousands of children with neurological disorders. No one has come close to Ken in establishing the academic origins and growth of Child Neurology. Through his years of tireless work and productivity, Ken has consistently exuded great warmth, a dazzling smile, and an infectious laugh. He has inspired countless others to reach for lofty goals, inspired by Ken’s many legacies. Ken with Steve Ashwal, his one-upon-a-time trainee at Minnesota, and longtime collaborator editing successive Ken and his wife of 35 years, pediatric neurologist Phyllis editions of Swaiman’s Pediatric Neurology. Sher, alternated their residences between Minneapolis and Tucson. Phyllis was a past member of the Executive Committee of the CNS, taught at the University of Miami and Practice,” with subsequent editions published in in Medical School, the University of Minnesota Medical School 1994, 1999, 2006, 2012 and 2017. As the book grew in and did research at the NIH. While in Arizona, she taught size and coverage, additional editors joined Ken: Steve at the University of Arizona School of Medicine, returned Ashwal (1999), Donna Ferriero (2006), Nina Schor (2012), to her artistic background and is an accomplished painter. and Andrea Gropman, Richard Finkel, Phillip Pearl, and Ken received unswerving support from Phyllis during his last Michael Shevell (2017). The growth of the discipline is of several illnesses, sharing their deep love as Ken reflected documented by the fact that the number of pages and on his life, a life so well lived. In addition to Phyllis, Ken is chapters has grown greatly: from 40 chapters/1,082 pages survived by children, Lisa Swaiman (Jim Grossman), Jerrold in 1975 to 170 chapters in 2017 (online version of >3,500 Swaiman, Barbara Swaiman (Mark Franklin), and Dana pages; shortened print version of 1432 pages). Hoberman (Bruce); and grandchildren, Isaac Swaiman, Sarah Grossman, Ethan Swaiman, Danielle Swaiman, The Journal, ‘Pediatric Neurology’. Although there Sawyer Franklin, Ryan Franklin, Jordan Hoberman and Benji were several journals that covered neurological disorders, Hoberman; and great grandson Everett Swaiman. it was in 1951 that the first issue of Neurology, the official journal of the American Academy of Neurology (AAN) Submitted by longtime colleagues and friends, appeared. Then, in 1975, the American Neurological Stephen Ashwal, MD Association founded the Annals of Neurology. Shortly N. Paul Rosman, MD thereafter and with a certain degree of debate and controversy, the CNS became co-sponsors of the Annals, with all society members getting a subscription to the Annals as part of their dues. Ken described in detail the process that led to his decision to develop a journal solely devoted to child neurology and within several years (1985), “Pediatric Neurology” appeared. The journal has grown remarkably, receives many contributions from all over the world and has a high impact factor. Ken continued as Editor-in-Chief until 2012 and in 2013, he turned over this position to Steve Roach who has maintained the high standard of the journal, with a steadily rising impact factor.

The word ‘retirement’ was not in Ken’s lexicon. He continued to attend CNS meetings, maintained close Ken with his wife of 35-years, Phyllis Sher, who first contacts with leaders of the CNF and was Editor and presented work at a CNS Annual Meeting in 1973, was co-author of chapters in the 2017 edition of the reference elected to serve on the CNS Executive Committee (1993-95), text that he began and has become an accomplished artist in retirement.

Child Neurology Society | Fall 2020 9 CONNECTING WITH COLLEAGUES Letter from the Editor

Lessons Learned From a Voice Not Heard Daniel J. Bonthius, MD, PhD, CNS Connections Editor

nlike most of the readers and contributors to this newsletter, I never met Ken Swaiman, and I am a lesser man for it. It seems It was no accident that child U the height of irony that I, the editor of a child neurology newsletter called neurologists chose the name “Connections,” would never have made a personal connection with the Connections for their newsletter. one individual who, more than anyone else, has led my own field of child neurology. And yet, sadly, it’s true. I never met the man. And so, with Dr. Swaiman’s death to prod and awaken It’s not that I lacked the opportunity. I often saw Dr. Swaiman at Child me, I urge my colleagues – and Neurology Society meetings, walking between meeting rooms, drinking especially newcomers to the coffee, or standing at posters. I could have introduced myself. field – to reach out to each other It’s not that I didn’t recognize him. Having served as President of every and to the people you admire, professional organization in child neurology and been the winner of to form the connections that their most prestigious awards, Ken Swaiman has been the face of child neurology for the past 50 years. How could anyone in the field not prompt us to grow as physicians, recognize him? scientists, and human beings. The time is now, before it’s It’s not that I didn’t hold him in awe. Author and editor of the most too late. influential textbook in the field, founder of our society, our foundation, and one of our most important journals, Ken Swaiman has been the guiding light of our profession. His name is all over my bookshelves, my

10 Child Neurology Society | Fall 2020 references, and my internal list of the “giants” in child neurology. Check out the And yet, I never met him. I never introduced myself to Dr. Swaiman because I assumed that the great man would CNS Lifelong Learning probably not be interested in me. I was a generation younger than him; I was not famous, and I didn’t want to website... be a pest. I know now, how wrong that reasoning was. I’ve learned from the people who knew him best that he was not just a visionary leader who mingled with the high and over 35 CME and mighty, but that he was a great teacher who loved meeting students and other “unknowns” and was dedicated to non-CME courses and their educations and futures in child neurology. I’ve further 3 Self-Assessment Exams learned that he was a friendly person who laughed often and exuded warmth and wisdom. Access by clicking I should have introduced myself. I should have told him about my life-long fascination with the brain, my research Lifelong Learning button in viral infections, and my most perplexing patients. I know now that he would have eaten it up. He would have on main CNS website listened intently and offered sage advice, with wisdom and humor, to me, as he did to so many others.

Unfortunately, I’ve learned this too late. Dr. Swaiman is now gone and so, too, is my chance to grow from his presence.

And yet, all is not lost. I’ve learned from this and can teach the lesson to others. The death of Dr. Swaiman has taught me the urgency of interacting with our mentors and our seniors while they’re here – learning from their experiences and growing from their wisdom.

Child neurologists are nice people. They like to talk. They like to learn. And they like to connect. It was no accident that child neurologists chose the name Connections for their newsletter. And so, with Dr. Swaiman’s death to prod and awaken me, I urge my colleagues – and especially newcomers to the field – to reach out to each other and to the people you admire, to form the connections that prompt us to grow as physicians, scientists, and human beings. The time is now, before it’s too late.

Child Neurology Society | Fall 2020 11 2020 Bernard Sachs Award Joseph G. Gleeson, MD Profile by Doris Trauner, MD

oseph Gerard Gleeson was born in Canoga Park, California, and grew up in J Woodland Hills, 22 miles east of Los Angeles in the San Fernando Valley. He was the oldest of four boys, so he quickly became accustomed to orderly chaos, a perfect training ground for his future endeavors. He attended an all-male Catholic high school in Encino, CA, where he enjoyed participating in high school plays and musicals. Not surprisingly, he usually had the lead role in those performances. After high school, Dr. Gleeson attended UC San Diego for his undergraduate education where he majored in chemistry. He spent a brief period doing a research elective in the laboratory of Dr. Doris Trauner, participating in a project on mitochondrial activity in an animal model of Reye syndrome. After graduation, he moved on to the University of Chicago Pritzker School of Medicine for his medical degree. During that time he worked with Dr. Peter Huttenlocher, one of the leaders in child neurology, and this experience solidified his interest in entering that field. It was during this time that, while filling out forms required for a research elective, he met the love of his life, MariJo Logeman. That research elective may have had the most lasting impact of any he did; they’ve been together ever since, and have been married for 28 years.

Following medical school, Dr. Gleeson moved further east, to Boston, where he fulfilled a dream of working with one of the people he most admired, Dr. Joseph Volpe. He completed his pediatrics and child neurology training at Boston Children’s Hospital, followed by a research fellowship at Harvard with Dr. Christopher Walsh. During this time, his research interest in the genetic underpinnings of neurodevelopmental disorders blossomed. His initial work focused on X-linked lissencephaly, and he identified the doublecortin (DCX) gene that was mutated in X-linked lissencephaly and double cortex syndrome, defined genotype-phenotype correlations, and provided a molecular diagnosis for patients. By studying DCX function, he defined the concept of nuclear-centrosome coupling in neuronal migration. He also demonstrated that DCX is a marker for neural stem cells, now a widely used marker.

Dr. Gleeson was recruited to UC San Diego after completion of his fellowship. He set up a neurogenetics lab and developed productive relationships with clinicians and researchers around the world. In order to study rare genetic disorders, he traveled to the Middle East, where in some countries and communities there is a higher rate of consanguinity, and recruited and examined entire families with genetic disorders. He focused his research on identifying new causes for recessive pediatric brain disease, by traveling extensively in the Middle East for patient evaluations and ascertainment. In doing so, he identified over half of the now 20+ genes mutated

12 Child Neurology Society | Fall 2020 in Joubert syndrome (JS), and linked JS to the ciliopathies. interacts. He has always been very excited to see the He identified defects in ciliary function in patient cells, many patients around the world first hand with the and performed the first cell-based screen to identify various conditions he was studying, and he has also modulators of ciliogenesis, which defined actin-regulatory always been very humbled by the difficulties the children pathways. His recent work has focused on recent work and their parents experienced with the poor outcomes is focused on identifying genes for neurodevelopmental from these severe conditions. Those families have been a and neurodegenerative disorders using a combination of driving force in his tireless efforts to find new genes, new recessive and de novo somatic mosaicism detection, to mechanisms, and potentially new treatments for those define potentially treatable conditions. He identified several devastating conditions. Joe truly embodies the values and mutations as potentially treatable neurodegenerative accomplishments underlying the Sachs award. diseases. His current work includes the use of exome sequencing to improve ability to diagnose and treat disease. Teaching has been an important facet of Dr. Gleeson’s career as well. He has trained a large number of graduate Dr. Gleeson quickly rose through the ranks to Professor. He students, medical students and post-doctoral research has remained at UC San Diego for his entire career, with the fellows, many of whom have gone on to academic exception of a brief detour to the east coast, where he was careers of their own with independent grant funding. He the Hess Professor in the Laboratory for Brain Diseases at is generous with his time and it is clear that he believes the Rockefeller Institute, and Director of Mendelian Genetics in preparing dedicated people to become the next at the New York Genome Center. He is currently the generation of research investigators. Rady Professor of Neurosciences and Pediatrics at UC San Diego, as well as the Director of Neuroscience at the Rady Along the way there has been another major driving force Children’s Institute of Genomic Medicine at Rady Children’s in Dr. Gleeson’s life – his family. Joe and MariJo have been Hospital San Diego. During his career, he has amassed married for 28 years; MariJo has a master’s degree in numerous accolades and research successes. He has enjoyed Public Health and works with early-stage pharmaceutical continuous grant funding for his research for many years. companies. They have three children: Sophia, age 14, He has published over 200 research papers in prestigious a freshman in high school; Jeremy, age 20, in his junior journals. Among his many awards, he received the Young year at Purdue University studying computer science; and Investigator Award from the Child Neurology Society in Matt, age 23, a graduate from Washington University 1998, the Klingenstein Award in the Neurosciences in with a degree in engineering and now at University 2001, the Burroughs Wellcome Fund Award in Translational College, London, working on a Master’s degree in Research in 2005, and was elected to the National Academy machine learning. Although the boys are now away at of Medicine in 2013. For many years he was a Howard school, they return often, and Dr. Gleeson loves spending Hughes Investigator. time with his family. They enjoy walking, hiking, and traveling together. He also enjoys sailing and running, and Now, in 2020, Dr. Gleeson is the recipient of the Bernard has run in a large number of marathons over the past 16 Sachs Award of the Child Neurology Society. This award years. Most recently, he began taking guitar lessons, and honors someone of international status who has done no doubt will master that craft as well. leading research in neuroscience with relevance to the care of children with neurological disorders. This describes Joe Gleeson is, in short, an extremely gifted, dedicated, Dr. Gleeson perfectly. His outstanding research has led and prolific physician scientist who has made and to new understanding about neurogenetic disorders, continues to make seminal discoveries that will and has opened the door to potential new treatments one day lead to new treatments for devastating for previously untreatable conditions. He is an open and neurodevelopmental conditions. He is also a loving generous collaborator and colleague as well, encouraging husband and father, a thoughtful and kind friend, a caring people to join his research efforts and to participate in mentor, and an eager, generous and open colleague and publishing their mutual work. He has amassed a very collaborator. Perhaps one year he will serenade us with large number of collaborators for these reasons, as well as a guitar medley at a post-Covid (one can only hope!) for the excitement that his research engenders in others. CNS Meeting. Meanwhile we can expect a superb Sachs He genuinely cares about the patients with whom he lecture from a colleague most deserving of this award.

Child Neurology Society | Fall 2020 13 2020 Hower Award Kenneth J. Mack MD, PhD Profile by John B. Bodensteiner, MD

his year’s Hower Award recipient is Kenneth Mack, MD, PhD. Currently Dr. T Mack is the Chief of the Division of Child and Adolescent Neurology in the Department of Neurology at the Mayo Clinic in Rochester, MN and Professor of Neurology and Pediatrics at the Mayo Clinic College of Medicine and Science. His numerous contributions to the Child Neurology Society and the discipline of child neurology throughout the United States and world-wide make him an outstanding choice for the Hower in this or any other year.

Born in Chicago as the youngest of four children, Ken was influenced by his older sister who became a nurse. He admits that his interest in medicine was sparked by her apparent enjoyment of her work. Dr. Mack left Chicago at age 18 years to enter the University of Illinois at Urbana-Champaign, from which he graduated with a BS with honors in Biology in 1978, and subsequently an MD and PhD in 1984. During this time he came under the influence of Dr. William Greenbaugh, who impressed the putative researcher with his obvious love for research and the enjoyment of the effort to find things out. While Dr. Mack was not a noteworthy athlete while in school, he was a member of the “Satanic Viruses” basketball club team composed of members of the research lab in which he worked while in Champaign-Urbana.

Dr. Mack did his graduate training at Washington University in St. Louis in both Pediatrics and Neurology. The list of noteworthy faculty members at “Wash U” at the time was impressive, but Dr. Mack recalls that Dr. Arthur Prensky made the biggest impression, noting that “Art was the one everybody took their hardest cases to for his opinion.” Dr. Joseph Volpe and Dr. Edwin Dodson also made lasting impressions on Dr. Mack as a resident.

Dr. Mack joined the faculty at the University of Wisconsin in 1990 as an assistant professor of Neurology, Pediatrics, and Physiology. He was promoted to associate professor in Madison and it was during this time that had the opportunity to work with Drs. Ray Chun and Rob Rust, who became life-long friends and both of whom were very influential members of the Child Neurology community for many years. It was in the early days of his career that Dr. Mack was recognized as a promising clinician and investigator with the bestowing of the Young Investigator Award of the Child Neurology Society in 1991. His young investigator award research was related to the induction of transcription factors in cerebral cortex. While in Madison he investigated synaptic plasticity and transcription factors. It is worth noting that several of the first recipients of the Young Investigator Award (renamed the Philip R. Dodge Young Investigator Award in 2004) are now being recognized for their

14 Child Neurology Society | Fall 2020 contributions to the Child Neurology community over the Dr. Mack recognized, early on, the importance of growing span of a career. As he became more and more involved and supporting the development of child neurology in clinical work Dr. Mack drifted toward clinical research as a specialty world-wide. He joined the International and away from the laboratory. Child Neurology Association (ICNA) in 2002 and quickly became a valued contributing member, serving on the The Mayo Clinic was fortunate enough to acquire the Executive Board of the organization from 2002-2018, talents of Dr. Mack in 2001 and he has remained in as Secretary General from 2004-2010, and as Chair the Division of Child and Adolescent Neurology since, of the Education Committee from 2010-2014. He has serving in several capacities including director of the D. encouraged many colleagues, residents and students to Sanford Pediatric Center (2006-2011), Director of the participate in ICNA congresses and become members Clinical Practice of the Division and Chief of the Division of this important organization. Dr. Mack has also been (2017). While at Mayo, his interest and expertise in a long-time member and contributor to the Society for the management of difficult headache problems and Neuroscience (1979-2004), the American Academy of movement disorders and tics has resulted in a well- Neurology and the International Headache Society ,as deserved reputation for thoughtful and considerate care well as the Movement Disorder Society and the Professors of his patients, and his opinion and advice is sought of Child Neurology. He has many published papers, by many patients, colleagues and referring physicians. abstracts, reviews, commentaries, editorials and chapters. His great clinical skills plus his temperate and mellow approach to even the most trying clinical situation has On a more personal level, Ken and his wife Pat are the made him a favorite of the residents and students and happy parents of three children and three grandchildren. their appreciation has been shown by the receipt of Remarking that there is “scarcely anything more fun three “Excellence in Teaching Awards”; in 2014 he was than playing with grandchildren” he anticipates, once honored by Mayo as the “Teacher of the Year.” the pandemic eases, spending a great deal of time doing just that. Dr. Mack is a warm, friendly, unfailingly Dr. Mack has been a member of the Child Neurology upbeat man with a tremendous capacity to stop what Society since 1989, serving the organization in many he is doing to listen to a question or supply information capacities. He was President from 2015-2017, and before without appearing to be annoyed by the interruption. that served on the Awards Committee, the Electronic He is forever willing to “give the benefit of the doubt” Communications Committee, the Long-Range Planning to everybody he encounters and this includes the many Committee, the Research Committee and the Executive difficult patients, as well as the colleagues, residents and Committee. Following his presidency, he chaired the students he deals with on a daily basis. Although there are Nominating Committee and represents the CNS on the many deserving Child Neurologists among us, I can think Annals of Neurology Oversight Committee. He also was of none more deserving of the Hower Award than Dr. Ken a key contributor, on short notice, to the production Mack. of the first Self-Assessment Examinations produced by and for the Child Neurology Society. It is fair to say that the frequency with which he has been appointed to the various committees of the Society is testament to the value placed on his contributions to those endeavors.

Child Neurology Society | Fall 2020 15 2020 Philip R. Dodge Young Investigator Award Hsiao-Tuan Chao, MD, PhD Profile by Gary D. Clark, MD

his year’s Philip R. Dodge Young Investigator Award recipient is Hsiao-Tuan T Chao, MD, PhD of Baylor College of Medicine (BCM). Tuan is an immensely talented individual who will be a leader in child neurology and in basic neuroscience of neurodevelopmental disorders. Her research has the potential to broaden our understanding of neural circuit development and function, with the long-term goal of advancing therapeutic strategies.

Dr. Chao, a native of Austin,Texas, was born to an engineer father (with a secret desire to be a neuroscientist) and a special education teacher mother. She spent much of her middle and high school years volunteering at her mother’s school, Rosedale, a beloved Austin Independent School District school for children with special needs. One of her mother’s favorite students was a young lady with constant hand wringing, who in retrospect probably had Rett Syndrome, a disorder that Dr. Chao would study for her PhD thesis. As student volunteers, Dr. Chao and her brother helped with daily care, therapies, and educational needs of her mother’s charges, while her father would make and donate equipment for therapy. Her brother serves as a career U.S. military officer and her mother retired from special education. Unfortunately, Dr. Chao lost her father early in 2020, but she continues to carry on his legacy. Her parents instilled in her a love of learning, a lifelong curiosity, and a service to others that comprise the foundation for an early promising career.

After completing her high school International Baccalaureate Diploma Program with honors in chemistry, physics and biology (top 1% of class, Presidential Award for Educational Excellence), she matriculated at the University of Texas at Austin (UT Austin) as a Plan II Honor’s College and Biochemistry double-major. With over 70 advanced credit hours, she entered as a sophomore and finished this challenging double major in only 3 years. It was at UT Austin where she first studied the mechanisms of fruit fly neurotransmitter release in the laboratory of Bing Zhang, PhD and met her future husband, Mingshan Xue, PhD, a neuroscientist at BCM.

Dr. Chao graduated summa cum laude with dual Bachelor of Arts and Bachelor of Science degrees from UT Austin and matriculated into BCM’s Medical Scientist Training Program as a McNair MSTP Scholar with The Robert and Janice McNair Foundation. She completed her PhD in Neuroscience with Christian Rosenmund, PhD and Huda Zoghbi, MD, where she made significant contributions to our understanding of excitatory and inhibitory neuronal mechanisms of disease in Rett and MECP2-duplication syndromes. Their research was among the first to uncover critical roles for MeCP2 in fine-tuning excitatory synaptic connections and regulating inhibitory neuronal signaling. The impacts of these discoveries are reflected by the

16 Child Neurology Society | Fall 2020 thirteen publications resulting from Dr. Chao’s doctoral Junior Member Award, STAT News Wunderkind award, and studies, including landmark first author publications post-doctoral research training fellowships from the Child in journals such as Nature and Neuron. The discovery Neurologist Career Development Program (CNCDP)-K12 linking disrupted inhibitory GABAergic signaling to Rett and the American Academy of Neurology in 2017. syndrome and to autism made a broad impact, and was recognized as one of the top 10 autism research findings In 2017, while still a medical resident, Hurricane Harvey of 2010 by Autism Speaks. In 2012, she graduated with flooded her single-story house. While the floodwater rapidly her MD and PhD degrees and was selected to present rose, the unsinkable Dr. Chao, from her attic, uploaded the commencement address for the graduate school of her application for the prestigious NIH Director’s Early biomedical sciences. Independence Award (DP5), an R01-equivalent grant awarded to outstanding young scientists to accelerate their Dr. Chao completed her Child Neurology residency training research independence. The DP5 award enabled her early in the Basic Neuroscience pathway at BCM and Texas transition to research independence, which was further Children’s Hospital (TCH) in 2017. During her residency supported by the Elterman PERF grant from the Child training, she served as Chief Resident from 2015-2016, Neurology Foundation, and the Burroughs Wellcome Fund and in 2016, she joined the laboratory of Hugo J. Bellen, Career Award for Medical Scientists. In 2018, Dr. Chao DVM, PhD at the Jan and Dan Duncan Neurological established her independent research laboratory at the NRI Research Institute (NRI) to pursue post-doctoral training as an Assistant Professor with joint primary appointments in neurogenetics and fruit fly neurobiology. She was in the departments of Pediatrics, Division of Neurology and instrumental in an international collaborative effort with Developmental Neuroscience, and Molecular and Human researchers in the Undiagnosed Diseases Network, BCM, Genetics at BCM, and was named a McNair Scholar. Her and the NRI that co-discovered the association between primary research focus is to elucidate the genetic and neural genetic variations in EBF3 and a neurodevelopmental mechanisms underlying neurodevelopmental disorders disorder manifesting in variable cognition, speech such as autism, intellectual disability, and epilepsy through impediments, poor muscle tone, impaired coordination integrating human genetics with mechanistic studies of and autistic behaviors. The discovery was published in the single gene disorders in fruit flies and mice. American Journal of Human Genetics and the disorder is now known as the Hypotonia, Ataxia and Delayed Development Dr. Chao is an exemplary child neurologist, a rigorous (HADD) syndrome. This generated much excitement in scholar, and a remarkable physician-scientist. She is the field as EBF3 was previously known to be an important committed to advancing the growth of physician-scientists meditator of inhibitory neuron development, further in child neurology. She encompasses the ideal qualities of supporting the emerging theme of disrupted inhibitory a Philip R. Dodge Young Investigator, and her proposed neuronal signaling as a shared pathogenic mechanism for research has tremendous potential to transform both our many neurodevelopmental disorders. To further expand mechanistic understanding of neurodevelopmental disorders our understanding of HADD syndrome, she established a and our field. multidisciplinary HADD syndrome clinic at Texas Children’s Hospital (TCH) that integrates the strengths of human genetics and neuroscience research at BCM. For this work, she received the Child Neurology Society Outstanding

Child Neurology Society | Fall 2020 17 2020 Outstanding Junior Member Award

Natalie K. Katz, MD, PhD Travis Larsh, MD Kshama Ojha, MD Sonal Sharma, MD Children’s Mercy Hospital & Children’s Hospital University of Louisville Children’s Mercy Clinics/University of Kansas Cleveland Clinic Louisville, Kentucky Hospital & Clinics/ Medical Center Cleveland, Ohio University of Kansas Kansas City, Missouri Medical Center Kansas City, Missouri

2020 M. Richard Koenigsberger Scholarship Award

Junior Members Register by October 12 to attend four dedicated Junior Member Seminars offered Week 1 of the CNS-ICNA Meeting: 1. Becoming a Physician Scientist in Pediatric Neurology Wednesday, October 14 2. Nurturing the Global Pipeline of Katelyn Bricker, MD, MS Academic Child Neurologists North Carolina Memorial Thursday, October 15 Hospital/University of 3. International Clinical Research Consortia North Carolina in Child Neurology: Get Involved! Chapel Hill, North Carolina Friday, October 16 4. Choosing your Career Track – Academic, Private Practice, and NGOs” Friday, October 16

18 Child Neurology Society | Fall 2020 TOGETHER•APART virtual OCTOBER 12-23,2020 2020

ICNA • CNS ICNA • CNS

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

Sharing Knowledge • Sowing Friendships • Spreading Hope TOGETHER•APART virtual2020

Want ICNA • CNS CME Credit? Complete CME survey ICNA • CNS online immediately AFTER THE MEETING: October 23-November 2

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

Sharing Knowledge • Sowing Friendships • Spreading Hope

The 2020 CNS Scientific Program The CNS Scientific Program is designed by and is primarily intended for child neurologists and professionals in other fields of study related to neurologic and developmental disorders in children and adolescents. “As a result of attending this meeting the physician will be better able to care for children with neurological disease through an understanding of recent advances in neuroscience, neuro-diagnostics and therapeutics relevant to child neurology.”

Accreditation Statement This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Minnesota Medical Association and Child Neurology Society. The Minnesota Medical Association (MMA) is accredited by the ACCME to provide continuing medical education for physicians.

CME Statement The Minnesota Medical Association designates this live activity for a maximum of 100.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

20 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 ICNA • CNS ICNA • CNS

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress YOU ARE49th Annual INVITED! Child Neurology Society Meeting 22 • Jo Wilmshurst, MB, BS, MD; President of the ICNA 23 • Phillip L. Pearl, MD; President, Child Neurology Society 10 THINGS 24 • To Know Before You Go (to your computer) SCHEDULE 30 • Monday, October 12 48 • Monday, October 19 31 • Tuesday, October 13 50 • Tuesday, October 20 34 • Wednesday, October 14 58 • Wednesday, October 21 38 • Thursday, October 15 66 • Thursday, October 22 41 • Friday, October 16 74 • Friday, October 23 SCHEDULE AT A GLANCE 79 • REGISTRATION 85 • Information and Fees INDUSTRY-SPONSORED SEMINARS & PRODUCT THEATERS 86 • SPONSOR/EXHIBITORS 89 • TOGETHER•APART virtual OCTOBER 12-23,2020 2020

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 21 You Are Invited!

On behalf of the International Child Neurology Association, it is my great pleasure to welcome you to the 16th International Child Neurology Congress being held October 12-23, 2020 in collaboration with the Child Neurology Society. Due to the COVID-19 pandemic, this will be the first virtual ICNC. Our congress theme is “Sharing Knowledge, Sowing Friendships, Spreading Hope”. The additional theme Together•Apart Virtual 2020 is the perfect concept for this congress. The ICNCs have truly set the stage as the key forum which provides the very latest and most relevant updates on child neurologic disorders from a global perspective. Speakers from across the six major geographic regions will present at the congress. The scientific program will feature internationally recognized experts, including themes of “Developmental and Epileptic Encephalopathies: What we know and what we do not know” (Nicola Specchio/Pritchard Award); “Update in Pediatric Neurometabolic Disorders 2020” (Lance Rodan/Linda de Meirleir Neurometabolic Award); “The Global Burden of Paediatric Neurological Disorders” (Charles Newton/Frank Ford Award) and “Dietary Therapies for Epilepsy in Low Resource Settings: Challenges and Success” (Suvasini Sharma/Sheila Wallace Award).

We are keen to hear from members of the ICNA and CNS community and hope you successfully submitted your proposals. Following the successful framework of previous congresses, the globally representative scientific committee, chaired by Prof Jonathan Mink, have selected the most innovative proposals to ensure a rich and diverse program guaranteeing that all delegates will leave inspired and with knowledge gained.

There will be opportunity for the newly established Council of the Future Leaders of ICNA (FLICNA), comprised of outstanding, regionally nominated senior child neurology residents, fellows and junior faculty to meet virtually and discuss strategy, as well as how the ICNA can support junior child neurologists. To promote access from clinicians based in low and low-middle income countries the registration rate has been significantly reduced. Based on popular demand there will be a strong educational program inclusive of master classes and teaching courses.

There will also be an opportunity for different child neurology subspecialty special interest groups to meet virtually. The networking opportunities building international collaborations is a key theme for the ICNA and the 2020 ICNC-CNS congress will be an ideal opportunity to pursue this. The congress promotes connecting clinicians involved in the phenotyping of unique clinical populations afflicted with specific neurological diseases with researchers in state-of-the-art research laboratories.

Please join us for a scientifically stimulating ICNC2020 program. We look forward to meeting virtually new colleagues and engaging with old friends. Following on from the COVID-19 pandemic, I hope that we can learn from the experience and identify new and positive ways to support each other and promote the health of children with neurologic disease.

On behalf of the ICNA board Jo Wilmshurst, MB, BS, MD President of the ICNA My fellow CNS and ICNA members, this Welcome Letter has undergone too many versions to anticipate anything at all but an unconventional meeting. But we will have a great meeting; Roger Larson guarantees it! Seriously, he and the CNS National Office are working so hard, with a great vendor and platform, to give us a superb conference, and in concert with the international crowd to boot. I am so pleased to co-host this conference with Jo Wilmshurst from ICNA and Jon Mink as chair of the Scientific Planning Committee. So many have worked so hard to coordinate these efforts; please plan to attend the sessions, which will now be spread out over two weeks, lest anyone has to sit in front of a screen and concentrate in aliquots as you would by sitting in a beautiful conference center in sunny San Diego!

This meeting has been years in the planning, but in Churchillian fashion, the best-laid plans of mice and men often go awry. In any case, we will still feature plenty of networking opportunities (Networking Lounges, Happy Hours and roundtable discussions), the Pellock Epilepsy Course for graduating child neurology residents, a Neurobiology of Disease symposium on head injury, and a scientific program replete with plenary award lectures, symposia, platform & poster presentations, Meet-the-Expert sessions, and workshops. The symposia span neuroimmunology, epilepsy, stroke, neuro-oncology, neuro-infectious disease, neuromuscular, movement disorders, neonatal neurology, behavioral neurology, neurogenetic- metabolic, neonatal neurology, neuro-opthalmology, and more. There is something for everyone, including a combination of practical knowledge and research advances, along with international representation that has been carefully integrated into the program. The organization of the meeting has been meticulous, but we are very busy trying to have all the material pre-recorded in time for uniformly high technical quality.

A highlight coming at the end of Week 1 will be the annual Child Neurology Foundation’s symposium, this year focusing on the diagnostic odyssey so familiar to us and our patients in the process of genetic diagnosis, symposia. We will also offer a very special series of evening programs in both Week 1 and Week 2. I so much enjoy experiencing other cultures when attending international conferences. Please join me in our novel course on AMERICAN CREATIVITY, INGENUITY, and DIVERSITY. We are going to demonstrate how the diversity that makes up American society has led to magnificent creativity and ingenuity in the arts, and I will be joined by my colleague and local bard, David Urion MD, past President of the Professors of Child Neurology, in an exploration of the literary works that help illustrate this aspect of American humanities. I will also be joined by colleagues from the Berklee School of Music here in Boston, drawing upon the diversity and expertise of their faculty, so that I will have a chance to play the music presented in the program with some of the greatest performing musicians in the world today. I’m delighted to share the joy of watching and listening to this incredible combo perform from your front row seat in front of the computer screen!

Phillip L. Pearl, MD President, Child Neurology Society William G. Lennox Chair, Boston Children’s Hospital Professor of Neurology, Harvard Medical School Institute of Music and Health, Berklee College of Music 10•THINGS To Know Before You Go (TO YOUR COMPUTER)

REGISTRATION FEES: 1 What’s Included Delegates paying registration fees (listed p55) will be eligible for: LIVE SESSIONS • All Open CME courses listed in this prospectus 3 (OCTOBER 12-23, 2020) • Neurobiology of Disease in Children (NDC): Traumatic Brain Injury requires payment of an additional course fee All sessions listed will be shown “live” once. Each session Special Interest Group meetings: Week 1; • will begin promptly at the dates & times to be listed in late September scheduled time, serially showing • Industry-Sponsored CME seminars and/or product pre-recorded lectures. A live theaters Week 1 & 2; dates & times to be listed Question and Answer period in late September will follow each set of pre- • Up to 100.25 CME credits. To earn credit, delegate must recorded lectures with Session attend the full session & click link at the end of the session Chairs and available presenters to answer a CME question. CME credits will be totaled and providing audible response a certificate issued beginning December to questions selected by a • Participation certificates (not good for validating CME moderator from among those credits earned) will be available immediately upon submitted in a side text/chatbox completing a course. during the lectures. • Because sessions are available On-Demand through March 2021, delegates paying registration fee may be able to earn needed CME credits for two years (2020 and 2021; # of credits will be based on when courses are completed). • Special thanks to the ABPN for a generous grant making it possible for non-CNS/ICNA members certified neurologists to attend at member rates. ON DEMAND SESSIONS 4 (NOVEMBER 2020 - MARCH 2021) All live sessions will be recorded and To Access most will be Sessions JUNIOR MEMBERS offered On Demand (24/7) On Demand thru 2 March 2021, via the virtual Four Junior Member seminars meeting platform You must be have been scheduled in Week 1 November 15, registered by for CNS & ICNA Junior Members 2020 thru October 23 and medical students to attend. March 31, 2021.

24 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 ICNA • CNS ICNA • CNS

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

INDUSTRY-SPONSORED CME SEMINARS AND/OR POSTERS & 7 PRODUCT THEATERS 5 VIDEO-POSTERS These will be listed along with all ICNA-CNS More than 550 posters (pdf files) and CME session in the “Sessions” listings of 100 video poster presentations (PPT the virtual meeting platform. A complete presentations) will be available On listing also appears on the page. Demand (24/7) during both Week 1 and Week 2, and On Demand through NOTE: Industry-sponsored sessions were designed and are staged in complete March 2021. independence of the CNS-ICNA meeting. A fee is paid to CNS & ICNA to link to external Posters & Video-Posters will be available websites on which these sessions are hosted; beginning Thursday, October 15. no endorsement of products, research or positions is implied by provision of this paid service.

SPONSORS & NETWORKING 6 EXHIBITORS 8 This meeting would not be • Special Interest Group Meetings. possible – this year especially – Nine 90-minute Special Interest Group (SIG) without the financial Meetings are scheduled during Week 1. Each support and participation may be followed by multiple pre-scheduled or of our corporate and non- spontaneously scheduled roundtable meetings profit partners. Show your involving up to 6 delegates at a time (signing up appreciation by visiting for wait list is an option). Sponsor & Exhibitor microsites • Networking Lounge & Roundtables (booths) available during Roundtables enabling up to 6 people to gather both Week 1 and Week 2, at a time to discuss anything and everything! and On Demand thru • “Hello World!” December 31, 2020. When first logging in, delegates will be asked to • Check up to 7 “Areas of Interest” (tags) Sponsors & Exhibitors will to help AI link you to others sharing your be available beginning interests Wednesday, October 14. • Introduce yourself with uploaded photo, brief bio, and brief video greeting

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 25 9

ChildNIGHT Neuro

American Creativity, Ingenuity, and Diversity

Thanks to our Gold Level Sponsors for supporting the joint international meeting and this special programming.

I am pleased to announce the development of a special in our society, as a means to reflect on how diversity educational/entertainment program, American Creativity, has enriched our culture and created great American art Ingenuity, and Diversity, offered to our colleagues from forms. The curriculum is formatted as presentations in around the world by the CNS as the host association words and music, and is done collaboratively between and country for this year’s International Child Neurology David Urion MD, the Charles Barlow Chair for Neurology Congress. This program was originally created earlier Education at Boston Children’s Hospital (and local bard this year in response to the pandemic and social unrest at Harvard Medical School) and myself. This was initiated during weekly town hall meetings in our neurology department, Available On during which we found that all Demand 24/7 department members, from the during and after medical and nursing staff to the CNS-ICNA technical, administrative, and Meeting. others gravitated and found meaning and solace. If you have the opportunity to partake of the program, you will note that it is organized into ten segments, each described briefly below. We invite you to watch one segment each night – whenever and wherever in the world it is nighttime for you – leading off your virtual “Happy Hour” networking with colleagues old and new. Those of you who still have a full week blocked off from when we originally hoped and planned to be together in San Diego may choose instead to binge watch the entire series Netflix-style. Either way, I hope you enjoy it.

26 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 PROGRAM OVERVIEW: 4. Literary reading: Excerpt from 7. “Es war beschreibt”, David Urion The Plague, by Albert Camus, story of a home visit 1. Literary reading: Weather, and WE THE PEOPLE, poem by by Claudia Rankine – Maya Angelou that was placed Musical selection: My Favorite commissioned by NY Times on the spacecraft Voyager at Things from The Sound of Music Book Review just after the killing the suggestion of Carl Sagan (1959), the last work of the of George Floyd in Minneapolis. prodigious Broadway writing Musical selection: Les feuilles duo Richard Rodgers and Oscar Musical selection: How High the mortes (1945 Hungarian-French Hammerstein, as interpreted Moon, composed by Morgan composer Joseph Kosma) in the iconic recording of Lewis (music) and Nancy rewritten as Autumn Leaves, saxophonist John Coltrane Hamilton (lyrics), and recorded as recorded by American (1961) by Benny Goodman (clarinetist) trumpeter Miles Davis on Blues in 1940, rewritten as Ornithology and Ballad album, featured 8. Literary reading: Excerpt from by Master Alto Saxophonist soloist on Kind of Blue (#1 “Sonny’s Blues”, short story by Charlie Parker (“Father of selling jazz album in the world) James Baldwin (1959), African Bebop”) in 1946. 1959 American poet writing of life in Harlem 2. Literary reading: Allegiance, 5. Literary reading: Psalm, by William Stafford (poet by Wislawa Szymborska, Musical selection: When Sunny laureate, conscientious objector) Nobel laureate (leaky Gets Blue (1959) and Those Winter Sundays by boundaries; ‘Only what is Robert Hayden (protégé of human can be truly foreign’) 9. Literary reading: The Dakini Auden, African American US Speaks, by Jennifer Welwood Poet Laureate). Musical selection: A Night in (on impermanence) Tunisia (1942) John Birks Musical selection: American “Dizzy” Gillespie (“Godfather Musical selection: Waltz for Song Book Standard It Could of Latin Jazz”) Debby (1956) Bill Evans, giant Happen to You (Jimmy van American pianist (& personal Heusen 1943) rewritten by 6. Literary reading: To be of favorite) African American Bebop Tenor Use by Marge Piercy Saxophonist Dexter Gordon as 10. Band Finale: Caravan (Edward Fried Bananas (1969) Musical selection: Nostalgia Kennedy “Duke” Ellington 1936), in Times Square 1959, African composer of the Far East Suite 3. Literary reading: Shoulders, American Jazz Master on (note the alternating African by Naomi Shihab Nye (Arab Creativity, bassist Charles safari sound/rhythms with -American poet who writes of Mingus, dies of ALS 1979, straight ahead American jazz connections across cultures) defined American music as: using blues form of sequential “what we play, that belongs perfect 4ths) Musical selection: What Is with the people who have a This Thing Called Love? (Cole feeling of freedom and like Porter 1929) rewritten by African to play together without American Pianist, Composer, discrimination.” and Arranger Tadd Dameron as Hot House 1945. Fun! With pleasure, let me share the members of this CNS Band Event, all of whom have toured internationally with the leading active jazz musicians in the world today. Jacques Bart-Schwarz – tenor sax, Professor of Music, Reeds Fun! Department, Berklee College of Music, native of Guadeloupe, blends Caribbean music with jazz Yoron Israel – drums, Chair and Professor, Percussion Department, Berklee College of Music, #3 album on national jazz charts 2004 Fun! Dan Fox – bass, Arlington-Boston Jazz Festival, Boston Jazz Ambassador to Cuba, alumnus, Berklee College of Music

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 27 10 PLENARY/AWARD LECTURES

TUESDAY, OCTOBER 20 THURSDAY, OCTOBER 22

6:00 AM – 6:55 AM PDT 6:00 AM – 6:55 AM PDT JOHN STOBO PRITCHARD LINDA DE MEIRLEIR AWARD LECTURE: NEUROMETABOLIC Developmental and Epileptic AWARD LECTURE : Encephalopathies: What We Know Update in Pediatric and What We Do Not Know Neurometabolic Disorders 2020 Nicola Specchio, MD, PhD, Lance Rodan, MD, FRCP(C); Bambino Gesu’ Children’s Hospital, Boston Children’s Hospital, IRCCS, Rome, Italy Harvard Medical School, Boston, Massachusetts, USA Introduced by Helen Cross, MB, ChB, PhD, OBE FRCP, FRCPCH Introduced by Ingrid Tein, MD

7:00 AM – 7:55 AM PDT 7:00 AM – 7:55 AM PDT BERNARD SACHS AWARD LECTURE: HOWER AWARD LECTURE: Genes as a Window into Migraine, Vertigo and Dizziness the Developing Brain Kenneth J. Mack, MD, PhD; Joseph G. Gleeson, MD; University of Mayo Clinic, Rochester, MN, USA California San Diego, Rady Children’s Introduced by Paul Youssef, MD Institute for Genomic Medicine, San Diego, California, USA Introduced by William Dobyns, MD FRIDAY, OCTOBER 23

6:00 AM – 6:55 AM PDT WEDNESDAY, OCTOBER 21 FRANK FORD AWARD LECTURE: The Global Burden of Paediatric 6:00 AM - 6:55 AM PDT Neurological Disorders SHEILA WALLACE AWARD LECTURE: Charles Newton, MD; Dietary Therapies for Epilepsy University of Oxford, Oxford, in Low Resource Settings: United Kingdom, KEMRI-Wellcome Challenges and Successes Trust Collaborative Programme, Suvasimi Sharma, MD, DM; Kilifi, Kenya Lady Hardinge Medical College and Introduced by Jo M. Wilmshurst, Associated Kalawati Saran MD, BS, MD Children’s Hospital, New Delhi, India Introduced by Pratibha Singhi, MBBS, MD, FIAP, FNAMS

7:00 AM - 7:55 AM PDT PHILIP R. DODGE YOUNG INVESTIGATOR AWARD LECTURE: Molecular and Cellular Mechanisms of Excitation and Inhibition in Neurodevelopmental Disorders Hsiao-Tuan Chao, MD, PhD; Jan and Dan Duncan Neurological Research Institute, Houston, Texas, USA Introduced by Huda Zoghbi, MD

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16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

ALL TIMES SHOWN: PACIFIC DAYLIGHT TIME 16th International Child Neurology Congress

49th AnnualOrganizer: Child Neurology Society MeetingCourse Description: Monday, October 12 Tim Lotze, MD; President, PCN; The Professors of Child Neurology Baylor College of Medicine, is attended by Residency Program 2:15 PM - 4:30 PM Texas Children’s Hospital, Directors, Division Chiefs, and PROFESSORS OF CHILD Houston, Texas, USA Program Coordinators who are NEUROLOGY (PCN): members of the organization. The CLINICIAN TRAINING AND Child Neurology in the session includes two parts. The first ASSESSMENT 21st Century: More than the part provides updates regarding Sum of our RVUs organizational business, national This session is limited to members Mary L. Zupanc, MD; involvement efforts of members, of the Professors of Child CHOC Neurosciences Institute, and updates from affiliated groups Neurology (PCN) and the Program University of California-Irvine; to include the AAP Section of Coordinators of Child Neurology CHOC-Children’s Hospital Neurology. The second part of the (PCCN) and is offered as Part II of of Orange County, meeting provides CME on selected the PCN Annual Business Meeting. Orange, California, USA topics which include a discussion The recorded lectures listed are of the current practice of child available for general viewing, but Creating a Clinical Educator neurology in the era of productivity Live Q&A will not be included on Track for Your Trainees metrics and development of the meeting platform. James Reese, Jr., MD, MPH, MA, a clinician educator track for FAAN; University of New Mexico, residents. Albuquerque, New Mexico, USA Learning Objectives: 1. Identify opportunities to educate residents regarding productivity metrics in clinical medicine. 2. Describe strategies for Learning Objectives and developing a clinical educator curriculum for residents seeking Impact Statement an academic career.

All Learning Objective statements listed for each session Impact Statements: should be read as responses to the following: ‘As a result 1. Attendees of the meeting will of this educational session, participants will be able to:’ receive a comprehensive update on the current state of residency All Impact Statements listed for each session should training. be read as responses to the following: ‘This educational 2. identify opportunities for session helped me to identify changes I could make ongoing program development at their own institution. in my practice related to:’

30 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Targeting the Central Nervous Additionally, participants will learn Tuesday, October 13 System: Experiences with Gene how to communicate a diagnosis Therapy for AADC Deficiency to patients and families, as well as 1:00 PM – 3:15 PM Toni Pearson, MBBS how to develop a plan of care and MEET THE EXPERTS: treatment that results in a lessening EXPERIMENTAL THERAPEUTICS: Gene Therapy Primer of disability and a resumption of Gene Therapy for Childhood Barry Byrne, MD, PhD; normal participation for the child. Neurological Disorders Child Health Research Institute, University of Florida, Learning Objectives: Course Description: Gainesville, Florida, USA 1. Appropriately consider the Participants will gain an place of functional neurologic understanding of the rapidly Experiences with Gene disorders in the context of evolving landscape of gene Therapy for Childhood pediatric disorders of movement therapy for neurological disorders Neuromuscular Disorders and pediatric paroxysmal of childhood. We will discuss the Diana Bharucha-Goebel, MD; disorders. basic principles of gene vector Children’s National Hospital & 2. Effectively explain the diagnosis development and delivery,and National Institutes of Health, of functional neurologic describe specific diseases for which Washington, DC, USA disorders to families and children gene therapy is currently approved 3. Develop and implement for clinical use or available as an Panel Discussion – Present appropriate treatment plans experimental treatment in clinical and Future Challenges in the for children with functional trials. Finally, we will discuss Development of Universally neurological disorders and challenges facing gene therapy Accessible New Therapies for their families as a result of this development, including cost and Ultra-Rare Diseases educational session. worldwide accessibility. Carsten G. Bönnemann, MD; National Institute of Neurological Impact Statements: Learning Objectives: Disorders and Stroke, 1. Accurately and confidently 1. Understand the principles of Bethesda, Maryland, USA diagnosing functional gene therapy development and neurological disorders in delivery. children. 2. Be able to describe how 3:30 PM – 5:45 PM 2. Communication with families different gene therapy strategies WORKSHOP: NEUROPSYCHIATRY/ and children about functional can be used to treat specific MOVEMENT DISORDERS: neurological disorders. neurologic diseases in children. Practical Management of 3. The creation of effective Functional Neurologic Diseases treatment and management Impact Statements: in Children plans for children with functional 1. Recognizing genetic disorders neurological disorders. that are amenable to treatment Course Description: with gene therapy. Attendees to this symposium will Organizer: 2. Identifying opportunities for gain knowledge and expertise Leon Dure, MD; patients with rare diseases to in the recognition of children University of Alabama participate in clinical trials of with functional neurologic at Birmingham, experimental therapies. disorders (FND), particularly Birmingham, Alabama, USA those manifesting as non-epileptic Organizer: seizures and movement disorders. Toni Pearson, MBBS; Washington University School of Medicine, St. Louis, Missouri, USA

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Psychogenic Non-Epileptic Impact Statements: 6:00 PM – 8:15 PM Seizures in a Pediatric Patient 1. Understanding the ethical MEET THE EXPERTS: Leon Dure, MD challenges of rising costs in all NEUROIMMUNOLOGY: healthcare systems. Para-infections and Seronegative Functional Neurologic Disorder 2. Explaining to patients how Autoimmune Encephalitis Presenting as a Movement Disorder healthcare affordability may in Children: Updates and in a Pediatric Patient affect access to certain new Controversies Shekeeb Mohammad, MD, FRACP, treatments now and in the PhD; The Children’s Hospital at future. Course Description: Westmead, Sydney, NSW, Australia Encephalitis in children are most Organizer: frequently infectious, parainfectious Practical Treatment and William D. Graf, MD, FAAP, FAAN; or autoimmune in etiology. Management of Functional Connecticut Children’s, CSF profile, next generation Neurological Disorders in Farmington, Connecticut, USA sequencing, and neuroimaging, Pediatric Patients can help differentiate infectious Aaron D. Fobian, PhD; Growing Disparities in International versus autoimmune causes in University of Alabama Healthcare – Ethical Perspectives some cases, but the etiology at Birmingham, on the Availability Versus remains uncertain in more than Birmingham, Alabama, USA Affordability Crisis half of the patients. Even when William D. Graf, MD, FAAP, FAAN autoimmune encephalitis (AE) is greatly suspected, CSF antibodies 6:00 PM – 8:15 PM Costly Drugs and Healthcare – are encountered in less than MEET THE EXPERTS: ETHICS: Challenges for Distributive Justice 50% of the cases. Furthermore, COSTLY DRUGS AND and the Inevitability of Rationing viruses can trigger autoimmune HEALTHCARE – ETHICS AND Amy Y. Tsou, MD, MSc; responses. Thus, differentiating VALUE PERSPECTIVES FROM ECRI Institute, Michael J Crescenz infectious versus parainfectious DIFFERENT HEALTHCARE VA Medical Center, and seronegative AE are common SYSTEMS Philadelphia, Pennsylvania, USA challenges encountered in clinical practice, and treatment strategies Course Description: The Economization of Healthcare in frequently overlap. Healthcare is expensive in all Germany – Lessons for a Science- countries and availability is based, Patient-centered and In this symposium we will often limited by affordability. Needs-orientated Care dive into the parainfectious The development of new ultra- Klaus-Peter Zimmer, MD PhD; phenomenon through 2 examples: expensive, first-in-class specialty UKGM, Standort Gießen / Justus- the pathophysiology of ADEM biopharmaceuticals for rare Liebig-Universität; and the post-herpetic NMDA neurological diseases exacerbates Gießen, Germany R ab encephalitis. We will also the health care affordability discuss controversies regarding problem. The objective of this Rising Prescription Drug Costs management of seronegative AE symposium is to discuss the in Canadian Healthcare – and the escalation of immune ethical challenges and practical The Implementation of therapy. approaches to the rising cost of National Pharmacare prescription drugs and healthcare Michael Shevell, MDCM, FRCP, Learning Objectives: in different healthcare systems. FCAHS; McGill University, 1. Acquire tools to help Montreal Children’s Hospital, differentiating infectious versus Learning Objectives: Montreal, Quebec, Canada non-infectious AE in the clinical 1. Understand why exorbitant drug practice. pricing poses direct challenges 2. Acknowledge the diagnostic for distributive justice, which challenges and controversies in is concerned with the fair the management of encephalitis distribution of benefits and in children and determine burdens across society. which encephalitic processes 2. Understand why costly may benefit from escalation in treatments inevitably lead immune therapy. to some type of “rationing” such as limitations of access (lack of insurance coverage), cost (excessive out-of-pocket expenses), or long wait times.

32 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Impact Statements: 6:00 PM – 8:15 PM Organizer: 1. Adequate management of SEMINAR: EPILEPSY: Katherine Nickels, MD, FAES, FAAN; Acute Encephalitis in children. Don’t Ask Don’t Tell, or Full Mayo Clinic College of Medicine, 2. Appropriate use of Disclosure? Discussing SUDEP Rochester, Minnesota, USA immunotherapy in Seronegative with Patients and Families in the autoimmune encephalitis. Global Community How Common is the Nightmare? Global Frequency and Causes of Organizer: Course Description: Mortality in Pediatric Epilepsy Cristina Fernandez-Carbonell, MD; In spite of uniform parental desire Elizabeth Donner, MD, MSc, FRCPC; Cohen’s Children Medical Center, for information, consistent SUDEP The Hospital for Sick Children, Lake Success, New York, USA counseling is not happening in University of Toronto, our pediatric neurology practices Toronto, Ontario, Canada Introduction: Infectious, globally. This session highlights Parainfectious and Autoimmune the important cultural barriers that What is our Current Understanding Encephalitis. Challenges in prevent child neurologists from of SUDEP in Pediatrics Clinical Practice discussing SUDEP by providing Omar Abdel-Mannan, MRCPCH, MA, Cristina Fernandez-Carbonell, MD information on the incidence and Great Ormond Street frequency of mortality in pediatric Hospital for Children, Parainfectious Encephalitis and epilepsy patients, as well as our London, UK ADEM. Updates and Controversies current understanding of the Silvia Tenembaum, MD; phathophysiology of SUDEP. This Panel Discussion National Paediatric Hospital will be followed by a panel of • Jeffrey Buchhalter, MD, PhD; experts throughout the globe who University of Calgary, Dr. Juan P. Garrahan, will describe the unique cultural Calgary, Alberta, Canada Buenos Aires, Argentina beliefs that affect discussing • J Helen Cross MB, ChB, PhD, SUDEP and mortality in his/her OBE FRCP, FRCPCH; Postviral Autoimmune Encephalitis: region. UCL Great Ormond Street The Case of Post-Herpetic Institute of Child Health, NMDAR Antibody Encephalitis Learning Objectives: London, UK Thaís Armangue, MD, PhD; 1. Gain a better understanding • Manjari Tripathi, DM; IDIBAPS-Hospital Clinic, of the frequency and potential All India Institute of University of Barcelona, pathophysiology of SUDEP in Medical Sciences, Sant Joan de Déu Children’s pediatric epilepsy patients Delhi, India Hospital, University of Barcelona, 2. Recognize differences in cultural • Viviana Venegas, MD; Barcelona, Spain practices regarding discussing Advanced Center of Epilepsy, SUDEP and mortality in pediatric Clinica Alemana de Santiago, Seronegative Autoimmune epilepsy patients Institute of Neurosurgery, Encephalitis. Updates and Santiago, Chile Controversies Impact Statements: Russell Dale, MRCP, PhD; 1. Understanding the parental Children’s Hospital at Westmead, desire for SUDEP and epilepsy University of Sydney, mortality counseling Sydney, NSW, Australia 2. Identifying potential cultural barriers that prevent the participant from discussing SUDEP and epilepsy-related mortality in his/her practice

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16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress

49th AnnualImpact Child Statements: Neurology Society MeetingWhy Can’t we Eradicate Measles – Wednesday, October 14 1. Understand the implications of Data from the Developing World drop in measles vaccination? – Pauline Samia, MBchB, 8:00 AM – 10:15 AM the immediate and long term MMed Peds, MPhil SEMINAR: picture. How this knowledge NEUROINFECTIOUS DISEASE: will help to convince patients Newer Understanding of the Measles Vaccination – Current to immunize their children? Immunological Basis of Situation and Consequences – How can each of us help in the Measles & SSPE A Global Perspective measles eradication process Banu Anlar, MD; 2. Understanding of the neuro- Hacettepe University, Course Description: immunology of the measles virus. Ankara, Turkey • Repercussions of the present Understanding different research trends in measles vaccination options in SSPE, with the hope 8:00 AM – 10:15 AM due to increasing exemptors – of a cure or treatment in the near SEMINAR: STROKE: short & long term effects on the future. Pediatric Stroke in the developed and developing world. Era of Advanced Genetics • Efforts required on the part of Organizer: the Child Neurology fraternity to Anaita Udwadia-Hegde, MD, Course Description: help with the drive for regional MRCPCH; The adverse health and and eventually global eradication. Jaslok Hospital & Research Centre, economic impacts of pediatric Lessons from Smallpox and Polio. SRCC NH Children’s Hospital, arterial ischemic stroke are • Latest understanding into Wadia Children’s Hospital, increasingly appreciated. the neuro-immunology of the Mumbai, India Mechanisms underlying measles virus, highlighting the childhood arterial ischemic role of research options in the Co-Organizer: stroke (AIS) are heterogeneous treatment and or cure of SSPE. Pauline Samia, MBchB, and poorly understood but MMed Peds, MPhil; critical for the development of Learning Objectives: Aga Khan University, targeted interventions. Cerebral 1. Know the present status Nairobi, Kenya vasculopathies are one of the major of measles with a global causes of pediatric stroke. Genetic perspective. How the present Impact of the Measles Outbreak – discoveries are being increasingly drop in immunization is going to A Global Perspective recognized as an important cause affect the clinical scenario – Kristen A. Feemster, MD, of many cerebral vasculopathies. today & in the future, along MPH, MSPHR; This symposium will highlight the with their role in the eradication Children’s Hospital of Philadelphia, role of advanced genetic analysis process. Philadelphia, Pennsylvania, USA in pediatric cerebrovascular 2. Understand the neuro- diseases, focusing on the common immunology of the measles Measles Eradication – and currently known genes and virus – understanding present Where do we Stand molecular pathways involved in and future research in the Anaita Udwadia-Hegde, MD, genetic cerebral vasculopathies. treatment and cure for SSPE. MRCPCH

34 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 The role of vascular smooth muscle Introduction: An Overview of 10:00 AM – 12:15 PM cell dysfunction will be highlighted, the Genetic Landscape of WORKSHOP: EPILEPSY: as well as the role of endothelial Pediatric Stroke PEDIATRIC EPILEPSY SURGERY: cell dysfunction in small vessel Moran Hausman-Kedem, MD; When, by Whom, and diseases. Current approaches for Pediatric Neurology Institute, What to Expect? the genetic evaluation and its Dana-Dwek Children’s Hospital, implementation in pediatric stroke Tel-Aviv Sourasky Medical Center, Course Description: based on a clinical and radiological- Tel Aviv, Israel Epilepsy surgery is a highly driven approach will be discussed, successful treatment option using a pattern-recognition Mechanistic Insights from for children with focal and approach. Existing challenges in Monogenic Causes of lesional epilepsy. Despite its the provision of accurate definition Cerebrovascular Diseases excellent seizure outcomes and and phenotyping of patients Vijeya Ganesan MD; cognitive benefits, surgery is still with vasculopathies in order UCL Great Ormond Street underutilized and a large treatment to facilitate future genotype– Institute of Child Health, gap remains between geographical phenotype correlations and identify London, UK regions worldwide. This symposium novel associations and disease aims to increase the awareness mechanisms will be highlighted Fits and Misfits: Radiographic of epilepsy surgery, inform the along with potential ways for Approach to Genetic audience about novel insights in enhancing gene discoveries in this Diagnosis in Stroke surgical indications, timing, seizure- developing field. Nomazulu Dlamini, MBBS, and cognitive outcomes, and their MRCPCH, MSc (Lon), PhD; determinants. We will present the Learning Objectives: The Hospital for Sick Children newly defined ILAE criteria for 1. Identify specific clinical as well and University of Toronto, different levels of care in pediatric as radiological phenotypes Toronto, Ontario, Canada epilepsy surgery centers and associated with common and address minimum requirements for newly described monogenic Clinical Management and surgical procedures in the context disorders related to pediatric Future Perspectives of Genetic of the existing treatment gap. stroke Cerebrovascular Diseases 2. Understand the basic concepts Patricia L. Musolino, MD, PhD; Learning Objectives: of cellular and molecular Massachusetts General Hospital, 1. Identify candidates for epilepsy pathways involved in genetic Harvard Medical School, surgery and counsel children medium to large cerebral steno- Boston, Massachusetts, USA and parents about its expected occlusive arteriopathies and seizure- and cognitive outcomes small vessel diseases. 2. Name the two levels of care for pediatric epilepsy Impact Statements: surgery centers and the main 1. Identify clinical and radiological requirements to establish such patterns of recently discovered centers genetic cerebral vasculopathies including arteriopathies and small-vessel diseases. 2. Understand the basic pathophysiological concepts involved in pediatric cerebral vasculopathies

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Impact Statements: Epilepsy Surgery in Children: Learning Objectives: 1. Indications for referral of Indications and Seizure-outcome 1. Identify the most common children with epilepsy for Prof. Dr. Kees P.J. Braun genetic causes of lissencephaly, presurgical evaluation polymicrogyria and cortical 2. Counselling of patients and Cognitive and Behavioural dysplasia. their parents about expected Outcome after Epilepsy Surgery 2. Determine the most appropriate outcomes of epilepsy surgery J Helen Cross MB, ChB, PhD, OBE genetic workup for children with FRCP, FRCPCH; UCL lissencephaly, polymicrogyria Organizer: Great Ormond Street and cortical dysplasia following Prof. Dr. Kees P.J. Braun, Institute of Child Health, review of clinical and imaging University Medical Center Utrecht, London UK features. UMCU Brain Center, Utrecht, Netherlands Criteria for Pediatric Impact Statements: Epilepsy Surgery Centers; 1. Recognising the imaging What about the Treatment Gap? features of different brain William D. Gaillard, MD; malformations. Children’s National Medical Center, 2. Understanding the most likely Washington, DC, USA genetic causes of lissencephaly, polymicrogyria and cortical.

Organizer: 10:30 AM – 12:45 AM Rick Leventer, FRACP, PhD; SEMINAR: NEUROGENETICS: The Royal Children’s Hospital Recent Advances in the Etiologies Melbourne, Parkville, and Mechanisms Underlying Victoria, Australia Common Brain Malformations Co-Organizer: Course Description: William Dobyns, MD; 1. Understand recent advances University of Washington, in the genetic causes and Seattle, Washington, USA mechanisms underlying common brain malformations, focusing Cortical Dysplasia: Linking Genes on polymicrogyria, lissencephaly to Seizure Generation and cortical dysplasia. Rick Leventer FRACP, PhD 2. Understand the imaging and phenotypic spectrum for the Lissencephaly: Novel Clinical common genetic causes of and Molecular Insights common brain malformations. Nataliya Di Donato, MD, 3. Understand how advances in Institute for Clinical Genetics, genetics have led to a better TU Dresden, understanding of seizure Dresden, Germany generation in focal cortical dysplasia. Polymicrogyria: A Clinical and Genetically Heterogenous Malformation Anna C. Jansen, MD, PhD, Peditiatric Neurology Unit, UZ Brussel, Brussels, Belgium

Conclusion & Future Directions William Dobyns, MD

36 ICNA • CNS | San Diego 2020 1:00 PM – 3:15 PM Introduction: Current Diagnostic Learning Objectives: SEMINAR: NEUROIMMUNOLOGY: Criteria of Neuromyelitis Optica 1. Learn the common pearls A New Era for Patients with Spectrum Disorders (NMOSD) and pitfalls in writing a good NMOSD, including Children Silvia N. Tenembaum, MD manuscript. 2. Better plan their medical Course Description: Diagnostic Biomarkers of NMOSD: research career path, especially • To learn current diagnostic AQP4-IgG and MOG-IgG for those in their early stages. criteria for NMO/NMOSD Thaís Armangue, MD, PhD; • To know updated information IDIBAPS-Hospital Clinic, Impact Statements: on the diagnostic biomarkers University of Barcelona, 1. Improve skills to write a scientific and appropriate laboratory Sant Joan de Déu Children’s paper. techniques Hospital, University of Barcelona, 2. Better plan one’s medical • To learn current rescue therapies Barcelona, Spain research career path. for acute events, and introducing novel relapse prevention Current Preventive Treatment Organizer: strategies for patients with Strategies for NMOSD Chang-Chun Wu, MD; NMOSD E. Ann Yeh, MD, MA, FRCPC Department of Pediatrics, Taipei City Hospital, Learning Objectives: New Era on Preventive Treatment Taipei, Taiwan 1. Learn new clinical and of NMOSD: Recently Approved neuroimaging diagnostic and Investigational Agents Co-Organizer: criteria for NMO/NMOSD and Tanuja Chitnis MD, FAAN; Hiroya Nishida, MD; corresponding biomarkers Harvard Medical School, Tokyo Metropolitan Institute 2. Receive updated information Boston, Massachusetts, USA of Medical Science, on current rescue therapies for Tokyo, Japan severe acute CNS events, and Treatment of Acute Clinical Events learn on relapse prevention Andrea Savransky, MD; What are the Common strategies, including novel National Pediatric Hospital Faults Editors See? immunosuppressive drugs. Dr. J. P. Garrahan, Jonathan W. Mink, MD, PhD; Buenos Aires, Argentina University of Rochester, Impact Statements: Rochester, New York, USA 1. The appropriate diagnosis of NMOSD 6:00 PM – 8:15 PM What PhD Brings to our 2. The relevant data about JUNIOR MEMBER SEMINAR: Research and Clinical Work? treatment options that should Becoming a Physician Scientist Pratibha Singhi, MBBS, MD, be considered for the correct in Pediatric Neurology FIAP, FNAMS; treatment of acute events Medanta, The Medicity, and relapse prevention with Course Description: Gurgaon, Haryana, India immunosuppression in children. How do we conduct a good research and write a good scientific Suggestions on Research Organizer: paper? We will approach this Outside a Medical Center Silvia N. Tenembaum, MD; universal question through three Takeru Honda, PhD; National Pediatric Hospital specific talks: “Common faults Tokyo Metropolitan Institute Dr. Juan P. Garrahan, editors see”, “What PhD brings to of Medical Science, Buenos Aires, Argentina research” and “Research outside a Tokyo, Japan medical center”. This symposium Co-Organizer: is aimed to help young physicians E. Ann Yeh, MD, MA, FRCPC; embark on their research journey. Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada

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16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress

49th AnnualImpact Child Statements: Neurology Society Meeting1:00 PM – 3:15 PM Thursday, October 15 1. How to design educational JUNIOR MEMBER SEMINAR: and training programs to Nurturing the Global Pipeline of 10:30 AM – 12:45 PM sustainably improve access to Academic Child Neurologists WORKSHOP: GLOBAL child neurology care in diverse NEUROLOGY: Training to settings Course Description: Bridge the Gap in Global 2. How to participate in There is an ever-growing Access to Child Neurology Care educational and training gap between the need for programs that increase access clinical Child Neurology and Course Description: to child neurology care in low to Neurodevelopmental Disabilities The participants will gain specific moderate resource settings. services and the number of trained knowledge about barriers to access practitioners throughout the to child neurology care in diverse Organizer: world. In this setting, nurturing and settings, with an emphasis on Alex R. Paciorkowski, MD; encouraging trainees and junior South America and Sub-Saharan University of Rochester faculty towards an academic career Africa. They will learn about Medical Center, path is a constant, but necessary, socioeconomic, geographic, and Rochester, New York, USA enterprise to ensure that clinically infrastructure barriers that continue focused research in our field to limit access to care. They will Child Neurology in Brazil, continues to scale as well. This acquire knowledge about three a Model and Challenges seminar will discuss the current specific settings where training Helio van der Linden, Jr., MD; challenges and opportunities programs are bridging these gaps Instituto de Neurologia de Goiânia, for training the next generation in access to child neurology care. Goiânia, Goiás, Brazil of Child Neurology physician- scientists both within the US Learning Objectives: Breaking New Ground in Zambia – and globally. There is an ever- 1. Understand some of the First Child Neurology Trainees growing gap between the need socioeconomic, geographic, Nfwama Kawatu, MD; for clinical Child Neurology and and infrastructure barriers that University Teaching Hospitals, Neurodevelopmental Disabilities continue to limit access to child Children’s Hospital, services and the number of trained neurology care globally Lusaka, Zambia practitioners throughout the 2. Become aware of a variety world. In this setting, nurturing and of approaches to training to Innovative Child Neurology encouraging trainees and junior overcome those barriers. Curriculum in Ecuador faculty towards an academic career Kevin Shapiro, MD, PhD; path is a constant, but necessary, Cortica Healthcare, enterprise to ensure that clinically Los Angeles, California, USA focused research in our field continues to scale as well. This seminar will discuss the current challenges and opportunities for training the next generation of Child Neurology physician- scientists both within the US and globally.

38 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Learning Objectives: 3:30 PM – 5:45 PM Organizer: 1. Understand and educate others MEET THE EXPERTS: BEHAVIORAL Ann M. Neumeyer, MD; about the training and funding NEUROLOGY: Management Massachusetts General Hospital, mechanisms available to support of Behavior in Children with Boston, Massachusetts, USA trainees and junior faculty Neurodevelopmental Disorders interested in an academic Child Moderator: Neurology career path. Course Description: Sarah Spence, MD PhD, 2. Be aware of the research and Pediatric Neurologists now care for Boston Children’s Hospital, service delivery priorities for more children and adolescents with Boston, Massachusetts, USA expanding Child Neurology neurodevelopmental disabilities access globally in addition to as the prevalence increases Case 1: Behavior Changes training more practitioners. worldwide. The neurobehavioral and Anxiety in a Child with care of these children is especially Tuberous Sclerosis Complex Impact Statements: challenging. This Meet the Shafali Spurling Jeste, MD; 1. Encouraging trainees and junior Experts session will address UCLA David Geffen faculty to pursue academic some of the common behavioral School of Medicine, career paths. management issues through Los Angeles, California, USA 2. Prioritizing lines of research case-based presentations of and training that are globally children with neurodevelopmental Case 2: Behavior Changes applicable. disorders including Autism, and Irritability in a Child with Tuberous Sclerosis, Fetal Alcohol Autism Spectrum Disorder Organizer: Syndrome and other intellectual Evdokia Anagnostou, MD; Alexander Li Cohen, MD, PhD; disabilities and Phelan McDermid University of Toronto, Boston Children’s Hospital, Syndrome. The Experts will discuss Bloorview Research Institute, Boston, Massachusetts, USA management of problems such Holland Bloorview Kids as irritability, behavior issues in a Rehabilitation Hospital, The NIH Perspective on child with epilepsy, Attention and Toronto, Ontario, Canada the Child Neurology executive function challenges and Physician-Scientist Workforce sleep. Case 3: Identifying and Treating Adam L. Hartman, MD, FAAP, Executive Function and FANA, FAES; Learning Objectives: Inattention in a Child with National Institute of 1. Treat four common behavior Fetal Alcohol Syndrome Neurological Disorders & Stroke challenges in children with Kirsten A. Donald MD, PhD, Neuroscience Center, NDD’s including irritability, University of Cape Town, Rockville, Maryland USA anxiety, attention and sleep. Cape Town, South Africa 2. Understand some of the Building a More Diverse behavior challenges in children Case 4: Behavior Changes and Pediatric Research Community with autism, tuberous sclerosis Sleep in a Child with Phelan Erika Augustine, MD, MS; complex, fetal alcohol syndrome, McDermid Syndrome University of Rochester and Phelan McDermid Syndrome, Ann M. Neumeyer, MD; Medical Center, their shared characteristics Massachusetts General Hospital, Rochester, New York, USA across disorders but also unique Boston, Massachusetts, USA challenges. Growing a Global(ly Capable) Pediatric Neurology Workforce Impact Statements: Jo M. Wilmshurst, MB, BS, MD, 1. Identifying behaviors in Red Cross War Memorial minimally verbal children and Children’s Hospital, University of NDD Cape Town, Cape Town, 2. Treatment of behaviors in Western Cape, South Africa children with NDD. TOGETHER•APART virtual OCTOBER 12-23,2020 2020

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6:00 PM – 8:15 PM the complexity of treatable 2. Enhancing collaboration and MEET THE EXPERTS: neurometabolic disorders will establishing networks in the NEUROMETABOLIC DISORDERS: enhance knowledge and impact global pediatric neurology Unravelling the Complexity outcomes through appropriate community dedicated to of Treatable Neurometabolic multidisciplinary management. improve the outcomes Disorders: A Case-based Session This symposium will focus on of children affected by the approach and management neurometabolic disorders. Course Description: of patients with treatable Organizer: Inborn errors of metabolism neurometabolic disorders, IEM Asuri N. Prasad, MBBS, MD, FRCPC, (IEM) are individually rare but associated with hyperammonemia, FRCPEdin, FAES; collectively they form a major pediatric neurotransmitter Schulich School of Medicine and group of treatable disorders in disorders, cerebral creatine Dentistry Western University, children. Affected children manifest deficiency syndromes and treatable London, Ontario, Canada with neurological and psychiatric IEMs associated epilepsies. symptoms that overlap more Primary Disorders of common conditions, and delayed Learning Objectives: Neurotransmitter Metabolism: diagnosis is not uncommon. 1. Understand key metabolic Challenges in Diagnosis & Enhancing knowledge and pathways involved in the Management understanding of these conditions biosynthesis of essential Asuri N. Prasad, MBBS, MD, FRCPC, will help neurologists establish neurotransmitters, the FRCPEdin, FAES early diagnosis. Unravelling clinical presentations and the role of the laboratory in Primary Hyperammonemic diagnosis of primary defects in Disorders: Neurological neurotransmitter metabolism Implications, Current Diagnosis 2. Identify biochemical and Management Strategies abnormalities and the Bindu Parayil Sankaran MD, clinical consequences in DM, FRACP, PhD; primary hyperammonemic Children Hospital at Westmead disorders, their diagnoses and NSW, Sydney, Australia management 3. Identify the clinical phenotypes, Epilepsies Associated with IEM diagnose various subtypes Annapurna Poduri, MD, MPH; and optimize the management Boston Children’s Hospital, of inherited cerebral creatine Harvard Medical School, deficiency syndromes Boston, Massachusetts, USA 4. Identify the phenotype and diagnose treatable metabolic Cerebral Creatine Deficiency causes of epilepsy in children Syndromes – An Underdiagnosed and adolescents. Entity: Clinical Aspects and Management Impact Statements: Sangeetha Yoganathan, MD, DNB, 1. Timely recognition, utilization DM; Christian Medical College, of appropriate biochemical and Tamil Nadu, India genetics testing to establish early diagnosis and improve outcomes in the four groups of metabolic disorders discussed through appropriate therapeutic interventions

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16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress

49th AnnualLearning Child Objectives: Neurology Society MeetingUpdate on mTOR Inhibition Friday, October 16 1. Learn about the spectrum of as Treatment for Neurological clinical presentation, importance Tuberous Sclerosis Complex (TSC) 8:00 AM – 10:15 AM of early diagnosis, adequate Manifestations MEET THE EXPERTS: treatment and accurate follow Lorena Lechuga-Becerra, MD; NEURO-CUTANEOUS DISORDERS: up. Sofia Salud, Mexico City, Mexico IN SPANISH: Neurocutaneous 2. Have a clear understanding Syndrome Iberoamerican Network of the benefits of having a Early Management and multidisciplinary team for the Strategies for the Treatment Course Description: treatment and surveillance of of Epilepsy Associated with The aim of the Iberoamerican patients and their families. Sturge Weber Syndrome network is to implement an Bolívar Quito-Betancourt MD; international collaboration Impact Statements: Hospital Monte Sinai, where healthcare professionals 1. The use of appropriate Cuenca, Ecuador (pediatric epileptologists, diagnostic and treatment pediatric neurologist, geneticists, algorithms concerning the Neurocognitive Problems neurosurgeons, pediatricians, management of these patients. and Impact of Individualized psychologists, nurses, etc.), 2. The development of a Neuropsychological affected families and caregivers multidisciplinary approach. Intervention for Children with from different countries share their Neurofibromatosis Type 1 (NF1) field of expertise, knowledge and Organizer: Alba Parra Checa, MSc; experiences. A platform enables Federico Jose Ramos, MD; Sant Joan de Déu Hospital, sharing and empowers families. Sant Joan de Déu Hospital, Barcelona, Spain Barcelona, Spain The main objective of the symposium is to emphasize the Introduction importance of early diagnosis, Federico Jose Ramos, MD adequate treatment and precise follow-up in the more prevalent Neurocutaneous Diseases.

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ICNA • CNS | TOGETHER•APART VIRTUAL 2020 41 Friday, October 16 • continued

10:30 AM – 12:45 PM Impact Statements: 10:30 AM – 12:45 PM SEMINAR: HEADACHE: 1. Implementing a comprehensive SEMINAR: NEUROINFLAMMATION: IN SPANISH: Migraine in Children plan for the management Interferonopathies and Adolescents – Diagnosis, of migraine in the pediatric Management and Treatment population that includes Course Description: pharmacological as well as non- The objectives are to be able to Course Description: pharmacological therapies. consider interferonopathies in the This seminar about Migraine 2. Implementing actions that will appropriate context of progressive in Children and Adolescents, address reintegration to school or static encephalopathies, to learn addressed in Spanish, will allow and management of psychiatric about their pathogenesis, and participants to learn and/or comorbidities in patients with possibilities of treatment. review the diagnostic criteria, migraine. epidemiology, therapeutic Learning Objectives: modalities, economic impact Organizer: 1. Think of a particular group of and quality of life data regarding Clarimar Borrero-Mejias, MD; disorders with variable age of Migraine in the Pediatric population Barrow Neurological Institute onset and severity, but typical in The Americas. Through lecture at Phoenix Children’s Hospital, constellation of symptoms. format and case presentation, University of Arizona – 2. Start the work-up or where to participants will learn and/or COM- Phoenix, refer if needed. review therapeutic modalities Phoenix, Arizona, USA for migraine, including cognitive Impact Statements: behavioral therapy (CBT), Migraine: Diagnosis, 1. This session allowed me to acute medications, preventive Epidemiology and Burden of consider a hereditary disorder medications, “natural” treatments Disease in The Americas in the differential diagnosis of and neuromodulation. Participants Edith Alva Moncayo MD; intrauterine infections, cerebral will learn about “ointments, President of Mexican Councile of calcifications, or hereditary concoctions and potions” and Neurology and Pediatric Neurology paraparesis. will learn perspectives related to in Medical Center La Raza IMSS, 2. I will include recessive interferon the level of scientific evidence for México pathway disorders in any child each therap. Participants will learn with slowly progressive or static about health habit modification, Migraine Therapies: neurological deficits, particularly accommodations in school, Medications and Beyond when more than one offspring exercise, meditation and psychiatric Denia Ramirez-Montealegre MD, is affected in the family albeit at comorbidities for patients with MPH, PhD; The University of different degrees. migraine. In addition, participants Tennessee Medical Center will learn about the similarities Knoxville, Tennessee, USA Organizer: and differences in the practice of Banu Anlar, MD; pediatric neurology (US vs Canada Migraine: Habits, School, Hacettepe University, vs Latin America), as it relates to Mind and Mood Ankara, Turkey the regional, cultural and social Clarimar Borrero-Mejias, MD norms, as well as the resources Case Presentations Illustrating available to each demographic. the Clinical Spectrum Banu Anlar, MD Learning Objectives: 1. Know the diagnostic criteria, Molecular Pathogenesis and epidemiology, therapeutic Treatment Targets modalities, economic impact Adeline Vanderver, MD; and quality of life data regarding Children’s Hospital of Philadelphia, Migraine in the Pediatric Philadelphia, Pennsylvania, USA population in The Americas. 2. Know the importance of Monogenic Interferonopathies health habit modification, with Non-Aicardi accommodations in school, Goutieres Phenotype exercise, meditation and Raphaela Goldbach-Mansky MD, addressing psychiatric MHS; Laboratory of NIAID/NIH, comorbidities for pediatric Bethesda, Maryland, USA patients with migraine. Discussion & Questions

42 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 10:30 AM – 12:45 PM Preterm MRI – Is it Immature The aim of this ‘Meet the Experts’ SEMINAR: NEONATAL Information? session for the Junior Members of NEUROLOGY: The Value of Terrie Inder, MBChB, MD; ICNA, non-member trainees and Magnetic Resonance Imaging Brigham and Women’s Hospital, anyone interested is to discuss in the Newborn Boston, Massachusetts, USA selected case presentations from different age groups and patient Course Description: MRI after Therapeutic populations, reflecting daily The participant will gain knowledge Hypothermia – Are there practice from different sites and regarding the appropriate use Cool Findings resources in an interactive way, with of MRI in the neonatal period Donna M. Ferriero, MD, MS a focus on the various tools we under a variety of conditions. In have to achieve a diagnosis. These particular, the parent and clinician Questions & Answers are ranging from the purely clinical, perspectives will be highlighted so the extended phenotype (imaging as to inform the decision-making and electrodiagnostics), biopsy, to process. 10:30 AM – 12:45 PM genetic and genomic investigations. MEET THE EXPERTS: Learning Objectives: NEUROMUSCULAR: Educational objectives for the 1. Make an informed decision The Many Faces of Pediatric symposium are three fold: about when to obtain an MRI in Neuromuscular Diseases: Cases, 1. Review clinical clues from a the newborn period. Approaches, Pearls and Challenges detailed history and points on 2. Understand what MRI offers the physical examination and in conditions such as neonatal Course Description: discuss when to consider a stroke, hypoxic-ischemic Neuromuscular diseases neuromuscular disease encephalopathy, congenital heart encompass a heterogenous 2. Teach how to integrate clinical disease and extreme prematurity. group of disorders which may be phenotype, and/or imaging and genetically determined, genetic or histology, as well as genetic tools Impact Statements: acquired, congenital or later onset, to arrive at a diagnosis 1. When to order MRI in the acute or chronic, and progressive, 3. How to confirm or refute a newborn. static or intermitted. Specific suspicious but not yet diagnostic 2. The need for MRI in the preterm therapies are emerging for an genotype, based on careful newborn and the appropriate increasing number of diseases with iterative clinical analysis time to get it. promising results for genetically determined diseases of the Learning Objectives: Organizer: neuromuscular system, including 1. Approach to most common Donna M. Ferriero, MD, MS; spinal muscular atrophy, Duchenne neuromuscular presentations UCSF Weill Institute for muscular dystrophy and treatable including early-onset muscle Neurosciences, myopathies, but also for acquired diseases, and recognize various San Francisco, California, USA conditions. The entry point for any important phenotypes in the directed therapy however is an pediatric age group using Tailor Made Prediction of accurate diagnosis. clinical, extended clinical, and Neonatal Stroke basic laboratory clues Linda S. de Vries, MD, PhD; 2. Learn to fully characterize the University Medical Center Utrecht, patient to create a differential the Netherlands diagnostic list of diagnostic possibilities based on the Congenital Heart Disease and patient presentation and exam- Brain MRI: The Heart of the Matter based localization according to Steven Paul Miller, MDCM, MAS, anatomic region and systems FRCPC; The Hospital for Sick involved, and combine traditional Children, The University of Toronto, and modern diagnostic testing Toronto, Ontario, Canada and consider management strategies including proactive treatment opportunities

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 43 Friday, October 16 • continued

Impact Statements: Learning Objectives: 3:30 PM – 5:45 PM 1. Awareness of the many different 1. Understand the range of JUNIOR MEMBER SEMINAR: presentations in the pediatric applications of Telemedicine International Clinical Research neuromuscular field and Technologies Consortia in Child Neurology: recognition of patients in whom 2. Avail of resources to connect Get Involved! a neuromuscular specialist with programs for increasing should be referred in the physician capacity for managing Course Description: ‘Pediatric Neurology’ practice neurological conditions The main objectives of this session 2. Recognition of most are to demonstrate the benefit and common clinical phenotypes, Impact Statements: need for international pediatric individualized clinical and 1. Recognizing applications of clinical trial consortia and how laboratory approaches, telemedicine as a plausible, to engage with international molecular diagnostic tests, attractive and cost-effective clinical research consortia in child and management strategies option to foster regional as well neurology. Content is geared including genetic counseling as international collaboration in to both “site” or local principal in the pediatric neuromuscular patient care and education investigators (PIs) and consortium disorders field 2. Improving capacity of referring PIs, regardless of geographic physicians in increasing self- location. Perspectives from Organizer: efficacy and confidence in co- consortium PIs, site/local PIs, and Göknur Haliloğlu, MD; managing neurological disorders institutions will be presented. Hacettepe University Children’s Hospital, Organizer: Learning Objectives: Ankara, Turkey Sucheta Joshi, MD, MS; 1. Gain a better understanding Michigan Medicine, of the benefit and need for Case Presentations Ann Arbor, Michigan, USA international pediatric clinical Göknur Haliloğlu, MD trial consortia. Co-Organizer: 2. Join and support an ongoing an Carsten G. Bönnemann, MD; Charuta Joshi, MBBS; international clinical research National Institute of Neurological Children’s Hospital Colorado, consortium in child neurology. Disorders and Stroke, Anchutz Medical Campus, Bethesda, Maryland, USA Aurora, Colorado, USA Impact Statements: 1. Joining and supporting an 1:00 PM – 3:15 PM Act Local, Reach Global: international clinical research consortium in child neurology. WORKSHOP: EPILEPSY/GENERAL The Impact of Telementoring 2. Seeking institutional and CHILD NEUROLOGY: through Project ECHO Sucheta Joshi, MD, MS financial support for an Telehealth – A Means to international clinical research Global Outreach The Guatemala-Colorado consortium in child neurology. Course Description: Child Neurology Telemedicine This workshop will bring together Experience Organizer: a panel of experts to review Diana Walleigh, MD; Adam L. Hartman, MD, FAAP, wide ranging applications of Children’s Hospital Colorado, FANA, FAES; National Institute of telemedicine technologies Anchutz Medical Campus, Neurological Disorders & Stroke and provide resources to an Aurora, Colorado, USA Neuroscience Center, Rockville, Maryland USA international audience to Guillermo Bolaños Ventura, MD; implement programs, collaborate Center for Human Development, Introduction with experts and colleagues FUNSALUD, Center for Adam L. Hartman, MD, FAAP, and develop virtual outreach Global Health, FANA, FAES capability. This session will address Retalhuleu, Guatemala resources for Child Neurologists, IPSS: Collaboration on Pediatric opportunities to empower primary Child Neurology Telehealth Stroke in 25 Countries care providers to increase their Special Interest Group: Current Heather J. Fullerton, MD, MAS; confidence, and self-efficacy in Landscape and Future Directions University of California, co-managing common neurological Charuta Joshi, MBBS conditions and partner with San Francisco, specialists in Pediatric Neurology San Francisco, California, USA care.

44 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 The Institutional Perspective on Two Learning Objectives: Historical view of the evaluation of International Research Consortia 1. Identify the different types of neurologic disorders. The impact Edwin Trevathan, MD, MPH; tools available for diagnosing of genetic progress and shift in Vanderbilt University children with neurologic diagnostic approach to genetics Medical Center, differences. viewed from the perspective of Nashville, Tennessee, USA 2. Identify the key elements of neuromuscular disorders; solving collaborating with families the unsolved, implications for Understanding the Etiology and mobilizing energy to use treatment. and Pathogenesis of Nodding resources effectively. James Dowling, MD, PhD; Syndrome in Eastern Africa Hospital for Sick Children, Richard Idro, MMED, PhD; Two Impact Statements: Toronto, Ontario, Canada Makerere University, 1. Developing a more effective Kampala, Uganda protocol to utilize the How to address disorders where appropriate tests and screeners the differential diagnosis includes Question & Answer for children in search of a genetic and non-genetic causes, diagnosis. from the perspective of epilepsy. 2. Improving communication and Role of imaging, role of genetics, 3:30 PM – 5:45 PM collaboration with families to progress and shift in diagnostic CHILD NEUROLOGY shorten the diagnostic journey. approach, evolving implications FOUNDATION SYMPOSIUM: for treatment, role of community Shortening the Diagnostic Organizer: engagement. Odyssey in Children with Child Neurology Foundation Ingrid E. Scheffer, AO, MBBS; Neurologic Conditions Scott L. Pomeroy, MD, PhD; The University of Melbourne, Harvard Medical School, Austin Health and Royal Course Description: Boston Children’s Hospital, Children’s Hospital, This symposium will bring together Boston, Massachusetts, USA Heidelberg, Victoria, Australia medical professionals, families and advocates from around the Welcome and Assessment Results Rare Neurological Diseases – world to discuss ways to shorten Scott L. Pomeroy, MD, PhD; Taking an Undiagnosed the diagnostic odyssey in children Harvard Medical School, Diseases Network Model with neurologic conditions. On Boston Children’s Hospital, average, it takes five years to Boston, Massachusetts, USA Panel Discussion diagnose a rare disease. This is • James Dowling, MD, PhD frustrating for both family and Family Perspective/Hope • E. Gay Grossman, Patient healthcare providers as it is for Diagnosis and Possibly Advocate critical, and sometimes lifesaving, Precision Treatment • Annapurna Poduri, MD, MPH; to get to a diagnosis and begin E. Gay Grossman, Patient Advocate, Boston Children’s Hospital, making informed decisions about Co-Founder ADCY5.org, Harvard Medical School, next steps in care for the child. San Diego, California, USA Boston, Massachusetts, USA During this session, participants • Scott L. Pomeroy, MD, PhD will receive an overview of the Family Support Through • Ingrid E. Scheffer, AO, MBBS current perspective, of families and Multidisciplinary • Beth Rosen Sheidley, MS, CGC professionals, on the challenges Programs/Genetic Counseling of getting to a diagnosis. The Beth Rosen Sheidley, MS, CGC; Close symposium will include speakers Boston Children’s Hospital, Scott L. Pomeroy, MD, PhD; who share information on both Boston, Massachusetts, USA Harvard Medical School, low-tech and high-tech tools to Boston Children’s Hospital, accelerate the diagnostic journey. Boston, Massachusetts, USA Participants will discuss the available tests and screens as well as how to best access and utilize these tools. We will also share information on best collaborate with families during the diagnostic process.

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 45 Friday, October 16 • continued

3:30 PM – 5:45 PM Organizer: These sessions include speakers MEET THE EXPERTS: Donald L. Gilbert, MD, MS; that are early career investigators MOVEMENT DISORDERS: Cincinnati Children’s Hospital at the NIH, public health officials Tics, Stereotypies, and Their Medical Center, working for the department of Look-a-Likes – Understanding and Cincinnati, Ohio, USA defense, and physicians in private Managing Repetitive Movements practice. Speakers will discuss Mimics – Functional (Psychogenic), options available for junior child Course Description: Drug-induced, and Otherwise neurologists in building bridges to This Meet the Experts Interest Donald L. Gilbert, MD, MS various research funding entities, Group session will address tics, carving out a subspecialty interest stereotypies, psychogenic mimics, Stereotypy Phenomenology within a group practice, as well as and similar-appearing movements. and Pathophysiology pursuing governmental careers The presenters will share their Harvey S. Singer MD; in the translation of scientific clinical experience on use of key Johns Hopkins Medicine, advances to the field. diagnostic features from home Kennedy Krieger Institute, videos and in-person neurological Baltimore, Maryland, USA Learning Objectives: evaluations in order to distinguish 1. Identify distinct career options challenging cases. They will also Tic Phenomenology and following training. share the latest research and Pathophysiology 2. Successfully transition into a neurobiological advances regarding Russell Dale, MRCP, PhD; long career role that best suits the pathophysiology and treatment Children’s Hospital at Westmead, their career needs. of these conditions. University of Sydney, Sydney, NSW, Australia Impact Statements: Learning Objectives: 1. Pursue as a child neurology 1. Use clinical skills to accurately attending. distinguish tics and stereotypies 6:00 PM – 8:15 PM 2. Identify clear steps to continue from “mimics” including JUNIOR MEMBER SEMINAR: on my career trajectory and drug-induced and functional Choosing Your Career Track – achieve my long-term career movement disorders. Academic, Private Practice, goals. 2. Discuss recent advances in and NGOs understanding of neurobiology Organizer: of tics, stereotypies, and Course Description: Payal Patel, MD; functional movement disorders. This session will discuss diverse Seattle Children’s Hospital, choices in building a career post- Seattle, Washington, USA Impact Statements: training in child neurology. Three 1. More accurate diagnosis based different career paths will be The Academic Track on phenomenology without discussed: Naila Makhani, MD, MPH; medical diagnostic testing 1. Academic/research careers – Yale University, 2. Implementation of treatment how to interact with chairs, New Haven, Connecticut, USA strategies starting with effective apply for jobs, negotiate time communication of diagnoses and for research or education The Private Practice Track treatment options to caregivers 2. Private practice – how to find Doug Smith, MD; a good practice, tips towards Minnesota Epilepsy Group, starting your clinical career and St. Paul, Minnesota, USA negotiating for dedicated time for your clinical interests The Off-the-Beaten-Path Track, 3. NGO and governmental jobs Working in Government (i.e. CDC) – how to pursue a Ana-Claire Meyer, MD, MHSH; non-traditional career path and US Army Medical Research and interact with multiple Development Command, governmental associations and Fort Detrick, Maryland, USA industry resources outside of the traditional clinical setting.

46 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 CREATING HOPE THROUGH INNOVATION

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CORPUS2790_Ad_FullPage-wBleed_8,5x11.indd 1 9/26/20 9:26 AM ICNA • CNS ICNA • CNS

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress

49th AnnualImpact Child Statements: Neurology Society Meeting7:15 AM – 7:25 AM Monday, October 19 1. To have a deeper understanding OVERVIEW OF of key concepts that enables CLINICAL ASPECTS 7:00 AM – 3:30 PM cutting edge management in Christopher C. Giza, MD SYMPOSIUM I: NEUROBIOLOGY one’s practice soon after injury OF DISEASE IN CHILDREN (NDC): and in follow-up. Traumatic Brain Injury (TBI) 2. To serve as an advocate for 7:25 AM – 7:50 AM prevention of TBI and to educate EPIDEMIOLOGY OF PEDIATRIC TBI Course Description: others about emerging concepts Alcy R. Torres, MD; Traumatic brain injury (TBI) in care and management. Boston University School of takes an enormous toll on the Medicine, Boston Medical Center, developing nervous system. NDC Organizer: Boston, Massachusetts, USA 2020 will focus on the topic Bernard L. Maria, MD, MBA, including a description of clinical Goryeb Children’s Hospital, 7:50 AM – 8:15 AM features, pathogenesis and its Morristown, New Jersey, USA SEVERE TBI AND NEUROCRITICAL management, as well as identifying CARE MONITORING future research directions. TBI not Supported by the National Mark Wainwright, MD, PhD; only contributes to high levels Institutes of Health (NIH grant Seattle Children’s Hospital, of childhood mortality but also 5R13NS040925-21), and the Child University of Washington, considerable morbidity demanding Neurology Society Seattle, Washington, USA the expertise of child neurologists at diagnosis and in follow-up, impacting learning and well-being. 8:15 AM – 8:40 AM SIDELINE ASSESSMENT OF Learning Objectives: CONCUSSION IN SPORT 1. To recognize the spectrum Javier Cárdenas, MD; of clinical presentations and 7:00 AM – 7:15 AM Barrow Concussion & complications arising from Brain Injury Center, OPENING COMMENTS/ traumatic brain injury in children. Barrow Neurological Institute, INTRODUCTION 2. To learn of latest developments Phoenix, Arizona, USA in the field and how best to Bernard L. Maria, MD, MBA manage resulting neurological complications 7:15 AM – 9:15 AM 8:40 AM – 9:05 AM SESSION I: CLINICAL EVALUATION OF Clinical Aspects and Diagnosis PEDIATRIC CONCUSSION AND MILD TBI Moderator: Sean Rose, MD; Christopher C. Giza, MD; Nationwide Children’s Hospital, UCLA – Mattel Children’s Hospital, Columbus, Ohio, USA Los Angeles, California, USA

48 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 9:05 AM – 9:15 AM 12:25 PM – 3:00 PM 2:05 PM – 2:30 PM QUESTION AND SESSION III: TRANSCRANIAL STIMULATION ANSWER SESSION TREATMENT AND MANAGEMENT AND RECOVERY Karen M. Barlow, MBChB, Co-Director and Moderator: MRCPCH(UK), FRACP; BREAK Lucia Braga, Neuroscientist, PhD; University of Queensland, SARAH Network of Brisbane, QLD, Australia Rehabilitation Hospitals, 9:30 AM – 11:20 AM Brasilia, Brazil SESSION II: PATHOGENESIS 2:30 PM – 2:55 PM SPORTS AND RECREATION Co-Director and Moderator: 12:25 PM – 12:50 PM IN CHILDREN WITH Mayumi Prins, PhD; POST-TRAUMATIC SEIZURES, NEURODEVELOPMENTAL Brain Injury Research Center, BIOMARKERS, AND EPILEPSY DISORDERS University of California Adam Numis, MD; Rujuta B. Wilson, MD; Los Angeles, UCSF-Benioff Children’s Hospital, UCLA David Geffen Los Angeles, California, USA University of California School of Medicine, San Francisco, Los Angeles, California, USA San Francisco, California, USA 9:30 AM – 9:55 AM OVERVIEW OF POST-TRAUMATIC 2:55 PM – 3:25 PM PATHOBIOLOGY OF TBI HEADACHE AND MIGRAINE SESSION IV: Mayuni Prins, PhD Heidi K. Blume, MD, MPH; FUTURE DIRECTIONS & QUESTION Seattle Children’s Hospital, AND ANSWER SESSION University of Washington, 9:55 AM – 10:20 AM Seattle, Washington, USA Moderator: SEX DIFFERENCES IN TBI Bernard L. Maria, MD, MBA Meeryo Choe, MD; UCLA Mattel Children’s Hospital, 1:15 PM – 1:40 PM Panelist: Los Angeles, California, USA EXERCISE AND CONCUSSION • Christopher C. Giza, MD John Leddy, MD; • Mayumi Prins, PhD Jacobs School of Medicine, • Karen Barlow, MBChB, 10:20 AM – 10:45 AM Buffalo, New York, USA MRCPCH(UK), FRACP ADVANCED NEUROIMAGING • Lucia Braga, Neuroscientist, PhD IN TBI • NINDS or NCI Program Officer Emily Dennis, PhD; 1:40 PM – 2:05 PM University of Utah, REHABILITATION FROM School of Medicine, PEDIATRIC MODERATE-SEVERE 3:25 PM – 3:30 PM Salt Lake City, Utah, USA TBI CLOSING COMMENTS Lucia Braga, Neuroscientist, PhD; Bernard L. Maria, MD, MBA SARAH Network of 10:45 AM – 11:10 AM Rehabilitation Hospitals, GENETIC AND MOLECULAR Brasilia, Brazil MARKERS FOR TBI Christopher C. Giza, MD

11:10 AM – 11:20 AM QUESTION AND ANSWER SESSION

BREAK TOGETHER•APART virtual OCTOBER 12-23,2020 2020

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 49 ICNA • CNS ICNA • CNS

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress

49th Annualperoxisomal Child functionNeurology could Society all be Meeting7:00 AM – 7:55 AM Tuesday, October 20 involved in DEE. Also, epilepsy BERNARD SACHS and epileptiform discharges might AWARD LECTURE: 6:00 AM – 6:55 AM impact on cognition via several Genes as a Window into JOHN STOBO PRITCHARD mechanisms, although they are not the Developing Brain AWARD LECTURE: fully understood. The correct and Joseph G. Gleeson, MD; Developmental and Epileptic early identification of a etiology in University of California San Diego, Encephalopathies: What We Know DEE might increase the chances Rady Children’s Institute for and What We Do Not Know of a targeted treatment regimen. Genomic Medicine, Nicola Specchio, MD, PhD, Interfering with neurobiological San Diego, California, USA Bambino Gesu’ Children’s Hospital, processes of the disease will be IRCCS, Rome, Italy the most successful way in order Course Description: to improve both the cognitive Discuss causes of childhood Course Description: disturbances and epilepsy that are neurological conditions including To review the evolution of the key features of DEE. intellectual disability, autism the concept of Epileptic spectrum disorder and brain Encephalopathy (EE) during the Learning Objectives: dysplasia. Focus on developing course of past years and analyze 1. Correctly define early onset an approach towards genetic how the current definition might severe epilepsies distinguishing investigation based upon clinical impact on both clinical practice conditions where epilepsy and presentation and family history and and research. Developmental epileptiform abnormalities are developing pathways towards new delay in children with epilepsy responsible for the cognitive treatments. could be the expression of decline from conditions where the etiology, consequence of the etiology is the major player Learning Objectives: intense epileptiform activity in the cognitive dysfunctions. 1. Differentiate between dominant, (seizures and EEG abnormalities), 2. Be updated regarding new recessive, de novo, somatic, and or due to the combination of neurobiological process of complex modes of inheritance. both factors. Therefore, the genetic origin which are 2. Understand differences between current ILAE classification responsible of developmental gene testing strategies and identified three electro-clinical and epileptic encephalopathy. their power to detect genetic entities that are those of mutations that can determine Developmental Encephalopathy, Impact Statements: underlying signs and symptoms. Epileptic Encephalopathy, and 1. Diagnoses different types of Developmental and Epileptic developmental and epileptic Encephalopathy (DEE). Many encephalopathy biological pathways could be 2. Improve their knowledge on involved in the pathogenesis of specific etiologies and targeted DEEs. DNA repair, transcriptional therapies in developmental and regulation, axon myelination, epileptic encephalopathies metabolite and ion transport, and

50 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Impact Statements: Impact Statements: Cardinal Presenting Features, 1. Approaches and limitations 1. The recognition and initial Rating Scales, and the Clinical in evaluating children with evaluation of children with Course of Opsoclonus- neurodevelopmental disease for opsoclonus-myoclonus-ataxia Myoclonus-Ataxia Syndrome underlying genetic causes to syndrome. Ming Lim, MD, PhD; enable more definitive genetic 2. The use of immunomodulatory Evelina London Children’s Hospital, diagnoses, agents in the early course of King’s Health Partners Academic 2. Approaches to selecting and long-term follow-up of Health Science Centre, targeted therapies for specific opsoclonus-myoclonus-ataxia London, United Kingdom mutations using antisense syndrome. oligonucleotides. Short and Long-term Organizer: Neurodevelopmental Outcomes Tim Lotze, MD; in Opsoclonus-Myoclonus- 10:30 AM – 12:45 PM Baylor College of Medicine, Ataxia Syndrome SYMPOSIUM: Texas Children’s Hospital, Wendy G. Mitchell MD; NEUROIMMUNOLOGY: Houston, Texas, USA Keck School of Medicine, International Consensus Children’s Hospital Los Angeles, Opinions in Opsoclonus- Introduction: Los Angeles, California, USA Myoclonus-Ataxia Syndrome Tim Lotze, MD

Course Description: Consensus Recommendations The objectives of this symposium for the Evaluation and Treatment on opsoclonus-myoclonus- of Opsoclonus-Myoclonus- ataxia syndrome (OMAS) are to Ataxia Syndrome provide participants with up-to- Mark Gorman, MD, date consensus opinions from a Boston Children’s Hospital, collaborative international OMAS Boston, Massachusetts, USA study group. Attendees will learn current epidemiology, diagnostic Recognized Etiologies and criteria, biological mechanisms of Emerging Biomarkers in disease, optimal treatment, and Opsoclonus-Myoclonus- long-term outcomes. Ataxia Syndrome Russell Dale, MRCP, PhD; Learning Objectives: Children’s Hospital at Westmead, 1. Explain cardinal presenting University of Sydney, features, ratings scales, and the Sydney, NSW, Australia clinical course of opsoclonus- myoclonus-ataxia syndrome (OMAS) 2. Apply common evaluation and treatment practices for patients with OMAS

TOGETHER•APART virtual OCTOBER 12-23,2020 2020

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 51 Tuesday, October 20 • continued

10:30 AM – 12:45 PM Pilipino Perspective on Learning Objectives: SYMPOSIUM: STROKE: Pediatric Stroke: Differences in 1. To inform attendees of the new PEDIATRIC STROKE: Etiologies and Management understandings of the molecular Hot Topics, Global Challenges Marilyn Tan, MD, FCNSP, FPNA, constitution of pediatric FPPS; University of the Philippines, neuronal-glial BTs and closely Course Description: Philippine General Hospital, aligned pediatric gliomas, so as Our aim is to provide practical Manila, Philippines to better direct therapies. updates and strategies to address 2. To summarize the potential the most pressing and controversial African Perspective on Pediatric molecular therapies available issues related to pediatric Stroke: Stroke in Children with HIV for pediatric neuronal-glial stroke. A focus on infectious/ Alvin Ndondo, MBChB, FCPaed BTs and how such therapy can inflammatory mechanisms and (SA); Red Cross War Memorial dramatically affect outcome; the acute management will emphasize Children’s Hospital, potential toxicities of these new practical clinical issues combined University of Cape Town, agents will also be discussed. with distinct but universal Cape Town, Western Cape Province, considerations of mechanism. South Africa Impact Statements: Speakers will be experts 1. Understand the molecular within an emerging childhood Infectious Mechanisms of differences between the cerebrovascular disease global Childhood Arterial Ischemic S different subtypes of pediatric network and will address the troke: Overview and Update on low-grade neuronal-glial tumors challenges of stroke management New Global Efforts and how these differences affect in resource-limited settings. Heather J. Fullerton, MD, MAS; management and prognosis University of California, 2. Understand the potential new Learning Objectives: San Francisco, therapies available for these 1. Approach the acute San Francisco, California, USA lesions, the indications for management of a child with molecular-targeted therapy and stroke with confidence based the common side effects of such on modern evidence-based best treatment. clinical practice, and 1:00 PM – 3:15 PM 2. Appreciate the possible roles SYMPOSIUM: Organizer: of specific infections and NEURO-ONCOLOGY: Roger J. Packer, MD; inflammation in the pathogenesis PEDIATRIC MIXED Children’s National Hospital, of childhood arterial ischemic NEURONAL-GLIAL TUMORS: Washington, DC, USA stroke and resultant treatment New Classifications, Molecular implications. Understandings and Targeted Neuroradiographic Features of Therapy Pediatric Neuronal-Glial Tumors Impact Statements: Gilbert Vézina, MD, FACR; 1. Evaluating children for infectious Course Description: Children’s National Hospital, causes of stroke. Pediatric mixed neuronal-glial Washington, DC, USA 2. Offering children hyperacute tumors are an increasingly stroke therapy. recognized subtype of childhood Histologic and Histoimmunologic brain tumors (BTs), frequently Classification of Pediatric Organizer: causing seizures. The most recent Mixed Neuronal-Glial Tumors Adam Kirton, MD; WHO classification of pediatric Brent Orr, MD, PhD; University of Calgary, BTs identifies 13 different neuronal- St. Jude’s Children’s Calgary, Alberta, Canada glial tumor types. Over the past Research Hospital, decades there has been an Memphis, Tennessee, USA Acute Stroke Management in explosion of knowledge concerning Children: An Overview with a their molecular makeup, with the Global Perspective majority having distinct molecular Mark MacKay, MBBS, PhD; signatures. This session will Royal Children’s Hospital, review the clinical, radiographic, Melbourne, Australia histopathologic and molecular aspects of neuronal-glial BTs and closely aligned low-grade gliomas and summarize new data concerning the effectiveness of novel molecular targeted approaches.

52 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Molecular Classification and 3. Electrophysiology evaluation Introduction to Resultant Therapeutic continues to be important in Charcot-Marie-Tooth Disease (CMT) Implications of Pediatric Mixed differential diagnosis of various Gyula Acsadi MD, PhD Neuronal-Glial Tumors CMTs from other types of David T. W. Jones, PhD; neuropathies, moreover some Genetic Basis of Charcot-Marie- Hopp Children’s Cancer Center, parameters like CMAP may Tooth Disease (CMT) Heidelberg, Germany serve as biomarkers in clinical Shawna Feely, MS, LGC; trial. Quantitative muscle MRI University of Iowa New Understandings and techniques are emerging as Hospitals & Clinics, Molecular-Targeted Therapies for potential biomarkers along Iowa City, Iowa, USA Pediatric Neuronal-Glial Tumors with some other biological Roger J. Packer, MD measurements. Validated Assessment Tools in 4. In vitro disease models and Natural History for CMT transgenic animal research are Timothy Estilow OTR/L; 3:30 PM – 5:45 PM aimed at understanding the The Children’s Hospital SYMPOSIUM: molecular pathology of CMTs of Philadelphia, NEUROMUSCULAR DISEASE: leading to developments of Philadelphia, Pennsylvania, USA Advances in Pediatric new therapeutic targets. Charcot-Marie-Tooth Disease Electrophysiology and Biomarkers Learning Objectives: Richard A. Lewis, MD; Course Description: 1. Learn about the genetic causes Cedars-Sinai Medical Center, Charcot-Marie-Tooth disease of CMT and acquire validated Los Angeles, California, USA (CMT) is a heterogenous group evaluation tools that can be used of peripheral nerve diseases and neuromuscular clinics. Molecular Basis of CMTs and it is the most prevalent genetic Cellular Drug Targets neuromuscular disease caused Impact Statements: Mario Saporta, MD, PhD, MBA, by mutations in more than one 1. Will help the audience to FAAN, University of Miami, hundred various genes. The onset learn about proper diagnostic Miami, Florida, USA of disease often falls into the strategies, which could make pediatric age group and may lead their neuromuscular practice to significant disability. more efficient. Employing the The Symposium will provide many validated functional assessment updates regarding the causes of tools will make the long term CMT, and will discuss validated progression of CMT more assessment tools as well as new accurate to assess. therapeutic approaches: 1. The genetic basis of various Organizer: forms of CMTs including novel Gyula Acsadi MD, PhD; rare forms will be presented. Connecticut Children’s Medical A rational strategy for genetic Center, University of Connecticut testing will be provided. School of Medicine, 2. New developments in Farmington, Connecticut, USA standardized clinical evaluation tools (CMPTPeds, CMTInf) will be discussed. These tools are employed for natural history data collection in pediatric CMT and they may serve as outcome measures in emerging treatment trials.

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 53 Tuesday, October 20 • continued

3:30 PM – 5:45 PM Diagnosis of Neonatal Seizures • An update in clinical care, SYMPOSIUM: by Clinical Signs, Amplitude- diagnosis and research in some NEONATAL SEIZURES: Integrated EEG and of the most frequent and lethal Practical Approaches to Conventional EEG infection diseases affecting CNS, Classification, Diagnosis Cecil D. Hahn, MD, MPH; like TB and Malaria, and Management The Hospital for Sick Children, • Discuss the acute neurological University of Toronto, manifestations associated with Course Description: Toronto, Ontario, Canada Arbovirus infections, The educational objective of this • Understand implementation symposium is to present key Treatment of Neonatal Seizures challenges for clinical trials findings from the International Informed by Current Evidence conducted in Low and Middle League Against Epilepsy’s Task Hans Hartmann, MD; Income Countries investigating Force on the Classification, Hannover Medical School, new therapeutic modalities for Diagnosis and Treatment of Clinic for Pediatric Kidney, tropical central nervous system Neonatal Seizures. Speakers will Liver and Metabolic Diseases, infectious diseases emphasize key concepts and Hannover, Germany management strategies that can be Learning Objectives: applied across a variety of practice Management of Neonatal Seizures 1. To learn to identify some of settings, including resource-limited in Resource-Limited Settings the most common tropical locations. Jo M. Wilmshurst, MB, BS, MD, neurological infectious diseases Red Cross War Memorial Children’s and how to establish the proper, Learning Objectives: Hospital, University of Cape Town, diagnosis and treatment. 1. Accurately diagnose and classify Cape Town, Western Cape, 2. To learn about the neurological neonatal seizures using clinical South Africa manifestations of acute signs, amplitude-integrated infections for arbovirus. EEG and conventional EEG, and assign a level of certainty 6:00 PM – 8:15 PM Impact Statements: to their diagnosis. SYMPOSIUM: 1. This educational session helped 2. Apply current evidence to NEUROINFECTIOUS DISEASE: me to identify changes I could optimally manage neonatal Tropical Infections of the CNS: make in my practice related seizures across a wide range A Worldwide Problem to identify some of the most of practice settings. common tropical neurological Course Description: infectious diseases and how to Learner Outcomes: Globalization, communications, establish the proper, diagnosis This education workshop helped and technology, have improved and treatment. me to identify changes I could the mobility of populations around 2. This educational session helped make in my practice related to: the world. Infectious diseases me to identify changes I could 1. Recognizing when to suspect previously limited to specific make in my practice related to neonatal seizures and how to geographic areas are n longer learn about the neurological confirm the diagnosis using restricted to their geographic manifestations of acute available resources. location or origin. Due to infections for arbovirus. 2. Managing neonatal seizures in an immigration and the popularity evidence-based fashion. of international travel, patients affected by infectious diseases Organizer: including malaria, tuberculosis, zika, Courtney J. Wusthoff, MD; dengue, chikungunya, and Ebola Stanford University, can be found anywhere in the Stanford, California, USA world. These infections may have devastating consequences for both Definition and Classification individuals and society, especially of Neonatal Seizures: if clinicians are not aware of them Insights from the ILAE Task Force and do not consider them in their Ronit Pressler, MD, PhD; differential diagnosis. Important Great Ormond Street advances have been made in both Hospital for Children, diagnosis and treatment of many London, UK of these infectious diseases. In this symposium we will:

54 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Organizer: 6:00 PM – 8:15 PM Beneath the Tip of the Iceberg: Maria Teresa Acosta, MD; SYMPOSIUM: MOVEMENT Comorbidities of National Human Genome DISORDERS: Lessons from Tourette Syndrome Research Institute, National Tourette Syndrome – Better Jennifer Vermilion, MD, Institutes of Health, Understanding of the University of Rochester, Bethesda, Maryland, USA Development of the Child Brain Rochester, New York, USA

Co-Organizer: Course Description: Non-Pharmacological Alfredo Cerisola, MD; Lessons learned from this Management: Anti-Boring University of the Republic, symposium about Tourette Lifestyles for Children with Uruguay syndrome include comorbid Tourette Syndrome disorders sometimes being more Huei-Shyong Wang, MD CNS Tuberculosis: Recent Concepts impairing than tics alone and in Diagnosis and Treatment how to avoid time-wasting and Pharmacological Therapy for Pratibha Singhi MBBS, MD, FIAP, disappointed regimens. This Tourette Syndrome: What FNAMS; Medanta, The Medicity, symposium will give audience a Medicines Can Do and Cannot Do Gurgaon, Haryana, India, Post better understanding of the Yoshiko Nomura, MD PhD; Graduate Institute of Medical development of the child brain. Yoshiko Nomura Neurological Education and Research Changing life style may help a lot. Clinic for Children, Chandigarh, India Otherwise, deep brain stimulation Tokyo, Japan may improve those refractory Cerebral Malaria: Recent Concepts patients. Deep Brain Stimulation in in Diagnosis and Treatment Tourette Syndrome Charles Newton, MD; Learning Objectives: Jonathan W. Mink, MD, PhD; University of Oxford, Oxford, 1. Learn the whole scope of clinical University of Rochester, United Kingdom, KEMRI-Wellcome manifestations of Tourette Rochester, New York, USA Trust Collaborative Programme, syndrome (TS), not just tics Kilifi, Kenya alone. 2. Apply non-pharmacological and Dengue, Zika and Chickungunya: pharmacological managements Acute Neuroinfections appropriately, and the role Marco T. Medina, Chevalier, FAAN; of deep brain stimulation in National Autonomous refractory TS. University of Honduras, Tegucigalpa, Honduras Impact Statements: 1. Try non-pharmacological Clinical Trials in Tropical Infections: management and appropriate Challenges and Successes medicine for children with Douglas G. Postels, MD, MS; Tourette syndrome; and deep Children’s National Medical Center, brain stimulation perhaps George Washington University, another choice for refractory Washington, DC, USA patients. 2. Avoid many irrelevant alternatives.

Organizer: Huei-Shyong Wang, MD; Chang Gung Children’s Hospital, Chang Gung University, Taoyuan, Taiwan

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 55 Tuesday, October 20 • continued

6:00 PM – 8:15 PM infantile spasms are managed Infantile Spasms: Peculiarities and SYMPOSIUM: EPILEPSY: not only by child neurologists, Challenges in Resource Limited Infantile Spasms – Current but also by paediatricians and Countries; Role of ACTH, Steroids, Management – A Global adult neurologists in many parts and Other Antiepileptic Drugs Perspective; The Way Forward of the world, this topic is relevant Pratibha Singhi, MBBS, MD, FIAP, for all. It is hoped that it would FNAMS Course Description: provide current information with This symposium will deal with an an international perspective and Evaluation of Infantile Spasms – important epileptic encephalopathy opportunities for collaborative Role of Genetics; Approach to ie Infantile Spams. Even Infantile research. a Child with IS in Japan Spasms constitute the commonest Shinichi Hirose, MD, PhD; devastating infantile epilepsy Learning Objectives: Fukuoka University, worldwide, there is a wide 1. Make a correct diagnosis and Fukuoka, Japan variability in their etiology, clinical plan a rational evaluation of a spectrum, and diagnostic and child with suspected infantile Diagnosis and Management of management protocols across spasms Infantile Spasms in the USA – the world. Despite some large 2. Make evidence based, rational New Drugs in the Pipeline; clinical trials, several challenges choices for the management What is the Way Forward? and uncertainties continue to exist. of Infantile Spasms, keeping in Shaun Hussain, MD, MS; There is lack of consensus even mind a global perspective. University of California among experts as to what exactly Los Angeles, constitutes hypsarrhythmia, and Impact Statements: Los Angeles, California, USA the certainty with which one can 1. Making an early and correct diagnose infantile spasms. Also, diagnosis in a child with Infantile Spasms – Concepts there are several unanswered suspected infantile spasms. and Differential Diagnosis; questions not only whether ACTH 2. Formulating appropriate the European Approach or oral steroids should be used, but management protocols for Towards Management also regarding the doses, dosing, children with infantile spasms. Alexis Arzimanoglou, MD; tapering, and duration of ACTH University Hospitals of Lyon, therapy and whether synthetic Organizer: Lyon, France and Children’s and natural ACTH should be Pratibha Singhi MBBS, MD, FIAP, Hospital San Juan de Dios, used. Similar questions also exist FNAMS; Medanta, Barcelona, Spain regarding the use of Vigabatrin, The Medicity, Gurgaon, Haryana, other antiepileptics, special diets India, Post Graduate Institute of and even surgery for the control Medical Education and Research, of IS. In this symposium, experts Chandigarh, India from across the globe will try to address these issues in light of the current scientific evidence and present the state of art information on the subject, with a global perspective. Some new drugs in pipeline and newer ways to conduct clinical trials will also be discussed. Since children with

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16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress

49th AnnualLearning Child Objectives: Neurology Society MeetingCourse Description: Wednesday, October 21 1. Understand the problems faced Discuss genetic, cellular, and neural in low resource settings, for circuit mechanisms underlying 6:00 AM – 6:55 AM prescribing and administering neurodevelopmental conditions SHEILA WALLACE dietary therapies for refractory characterized by autism, intellectual AWARD LECTURE: childhood epilepsy. disability, and epilepsy. Focus Dietary Therapies for Epilepsy 2. Learn strategies for low on integrating multidisciplinary in Low Resource Settings: cost delivery of the diet in approaches in model organisms Challenges and Successes resource constrained and including fruit flies and mice with Suvasini Sharma, MD, DM; underpriviledged populations. genetic investigation based on Lady Hardinge Medical College clinical findings. and Associated Kalawati Impact Statements: Saran Children’s Hospital, 1. Consider and offer the option Learning Objectives: New Delhi, India of ketogenic diet if medically 1. Recognize how the identification indicated, even in low and study of the genetic Course Description: socioeconomic populations, if underpinnings of “rare” disorders I have been working in the field the caregivers are motivated. can uncover biological pathways of Dietary therapies of childhood 2. Use simple and flexible shared with more common epilepsy for the last 15 years. I approaches to the use of the conditions. will share my experience with ketogenic diet for low resource 2. Understand the application of the use of ketogenic diets and settings functional studies in fruit fly and its modifications in India. I work mouse model organisms and in a low resource setting, and in their power to reveal pathogenic a cultural mileau which is very 7:00 AM – 7:55 AM gene alterations and underlying unfamiliar with ketogenic diet. PHILIP R. DODGE disease mechanisms. In this talk, I will discuss the YOUNG INVESTIGATOR challenges faced by pediatric AWARD LECTURE: Impact Statements: neurologists and parents who The Impact of Serendipity: 1. Approaches and limitations wish to use the diet in children From “Rare” Neurodevelopmental in the evaluation, diagnosis, with refractory epilepsy; and how Disorders to Common Insights and prognosis of children with we have used simple low cost Hsiao-Tuan Chao, MD, PhD; neurodevelopmental disorders. innovations to overcome these Baylor College of Medicine, 2. Approaches to identifying challenges. We have evolved from Houston, Texas, USA genetic etiologies underlying the use of the classic ketogenic diet neurodevelopmental disorders. to the flexible use of the modified Atkins diet, which we have demonstrated to be efficacious in randomized controlled trials.

58 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 10:30 AM – 12:45 PM Impact Statements: MECP2 Duplication Disorder: SYMPOSIUM: NEUROGENETICS: 1. Evaluation, diagnosis, and Understanding the Developmental Current Status of management of these Trajectory and Potential Therapies Developmental Encephalopathies: developmental encephalopathies Sarika U. Peters, PhD; Rett Syndrome, MECP2 including directing these Vanderbilt University Duplication Disorder, CDKL5 children to clinical centers Medical Center Deficiency Disorder, and focusing on these disorders. Nashville, Tennessee, USA FOXG1 Disorder 2. Educate and advocate for parents and other caregivers Recent Progress in Course Description: regarding the therapeutic Genotype-Phenotype • To understand the recent opportunities available Correlations in FOXG1 Disorder advances in the developmental or under development Knut Brockmann, MD; encephalopathies, namely, Rett for these developmental Interdisciplinary Pediatric Center syndrome, MECP2 Duplication encephalopathies. for Children with Developmental Disorder, CDKL5 Deficiency Disabilities and Severe Chronic Disorder and FOXG1 Disorder Organizer: Disorders Children’s Hospital, through comparison of the Alan Percy, MD; University Medical Center, important similarities and University of Alabama at University of Göttingen, critical differentiating features Birmingham, Göttingen, Germany of this expanding group of Birmingham, Alabama, USA neurodevelopmental disorders; Comparison of the Core • To understand the phenotype- Rett Syndrome: Features of the Developmental genotype relationships that Current Status and Encephalopathies from the characterize each disorder; and Therapeutic Considerations Rett Natural History Study • To promote the existing and Jeffrey L. Neul, MD, PhD; Eric Marsh, MD, PhD; emerging clinical trials that Vanderbilt Kennedy Center, Children’s Hospital of Philadelphia, offer the potential for disease- Nashville, Tennessee, USA Perelman School of Medicine at modifying or curative promise. the University of Pennsylvania, Philadelphia, Pennsylvania, USA Learning Objectives: 1. To understand the recent advances in the developmental encephalopathies, namely, Rett syndrome, MECP2 Duplication Disorder, CDKL5 Deficiency Disorder and FOXG1 Disorder through comparison of the important similarities and critical differentiating features of this expanding group of neurodevelopmental disorders including clinical trajectories and phenotype-genotype correlations 2. Understand the current strategies and challenges to develop and promote clinical trials that offer the potential for disease-modifying or curative therapeutics. TOGETHER•APART virtual OCTOBER 12-23,2020 2020

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 59 Wednesday, October 21 • continued

10:30 AM – 12:45 PM Impact Statements: 1:00 PM – 3:15 PM SYMPOSIUM: 1. Understanding advanced SYMPOSIUM: COGNITIVE- NEUROIMMUNOLOGY: technologies in diagnosing BEHAVIORAL NEUROLOGY: Cutting Edge Technology in neuroinflammatory diseases The Molecular & Cellular Basis Neuroinflammation: Advancing 2. Potential involvement in the of Developmental Cognitive & Science and Increasing Capacity in global health and capacity Behavioral Disorders Low and Middle-income Countries building process Course Description: Course Description: Organizer: • The overall educational This symposium will provide an Soe Mar, MD; objective of this symposium is overview of advanced technologies, St. Louis Children’s Hospital, to expose child neurologists such as metagenomic next- Washington University to cutting-edge insights into generation sequencing, phage School of Medicine, the developmental roots of display and enhanced virome St. Louis, Missouri, USA pediatric neurological disorders, sequencing, to identify evidence particularly those influencing of infection or autoantibodies in Technologies in LMIC, Advancing cognition, language, and patients with neuroinflammation Science and Increasing Capacity behavior. such as infectious encephalitis Soe Mar, MD • Many disorders in child (IE) and autoimmune encephalitis neurology – particularly (AE). We will also discuss the Decoding Neuroinflammation with those that are manifest by high mortality and morbidity of Metagenomics and Phage Display cognitive and behavioral IE and AE in low and middle- Michael Wilson, M.D, MAS; dysfunction, the failure to reach income countries (LMIC) and UCSF Well Institute for developmental milestones, potential application of these Neurosciences School of Medicine, dysmorphisms, and congenital technologies as well as capacity San Francisco, California, USA epilepsies – are attributable to building in LMIC. Upon completion fundamental aberrations during of this symposium, participants Detecting Hidden Virus cerebrogenesis, whether genetic will become familiar with new with Enhanced Human or acquired. To that extent, a technologies for pathogen and Virome Sequencing child neurologist might actually antibody discovery; understand Kristine Wylie, PhD; be viewed as a “translational the impact of infectious and Washington University developmental biologist”. Newer autoimmune encephalitis in LMIC School of Medicine, insights and tools in cell and and potential usage of technology St. Louis, Missouri, USA molecular biology (e.g., human to advance science, to save brains induced pluripotent stem cells, and to build capacity in LMIC. The Impact of Infectious and genome editing, organoids, Autoimmune Encephalitis in LMIC whole genome sequencing, Learning Objectives: Aye Mya Min Aye, MB.BS, M.Med.Sc; single cell ‘omics, epigenetic 1. To understand cutting edge Yangon Children’s Hospital, modeling, live cell imaging, technologies which can Yangon, Myanmar high-throughput high content detect pathogens directly screening, etc.), have increased by sequencing-based our ability to understand both approaches and indirectly normal cerebrogenic processes with comprehensive serology and the types of abnormalities assays, along with autoantibody that might occur in those discovery in patients with non- processes which might produce infectious encephalitis. the disorders we, as child 2. To understand the impact of neurologists, treat. Although infectious and autoimmune many of these insights are so encephalitis in LMIC and possible new that they have not yet ways to build research capacity yielded concrete treatments, in LMIC they certainly have started to suggest ways to diagnose and

60 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 stratify patients early and to Co-Organizers: 1:00 PM – 3:15 PM offer potential drug targets. Evan Y. Snyder MD, PhD, FAAP; SYMPOSIUM: SLEEP: This symposium seeks to Sanford Burnham Prebys Integrating Pediatric Sleep discuss some of the cutting- Medical Discovery Institute, Medicine into Child Neurology edge research that might yield UC San Diego School of Medicine, a better understanding of the San Diego, California, USA Course Description: cellular and molecular basis of Better understanding of various Doris Trauner MD; some categories in this class of sleep disorders encountered in the UC San Diego, disorders. child neurology practice, how to La Jolla, California, USA • The format for each of the 4 read the sleep study report that representative categories below will be generated by the sleep Introduction will be as follows: (1) a 5 min. physician and sent to the referring Doris Trauner MD introduction to the clinical entity; child neurologist, what treatment (2) a 20 min. synopsis of some options are available for these Genetic Epilepsy Syndromes of the cutting-edge molecular sleep disorders including insomnia, Annapurna Poduri, MD, MPH; and cellular research and/or and finally, when these patient Boston Children’s Hospital, modeling ongoing in that entity; should be referred to a sleep Harvard Medical School, (3) a 5 min. conclusion by the physician. Boston, Massachusetts, USA first speaker with an emphasis on the therapeutic implications Joseph G. Gleeson, MD; Learning Objectives: of the new scientific insights. University of California San Diego, 1. Incorporate better screening Rady Children’s Institute questions and order appropriate Learning Objectives: for Genomic Medicine, diagnostic tests in their 1. Understand how and why a San Diego, California, USA evaluation of children in child particular clinical entity emerged neurology clinics to assess and as an aberration of normal Autism confirm the underlying sleep developmental processes Adi Aran, MD, disorder. 2. Envision where future diagnostic Shaare Zedek Medical Center, 2. Initiate management strategies and therapeutic options may lie. Hebrew University, to treat the underlying sleep Jerusalem, Israel disorder Impact Statements: 1. Counseling patients and their Alysson R. Muotri, PhD; Impact Statements: families with regard to the cause UC San Diego School of Medicine, 1. Diagnose and manage comorbid of a disorder and the likelihood San Diego, California, USA or primary sleep problems in of it’s being observed in future child neurology offspring or future generations Neuropsychiatric Disorders 2. Appropriate referral to sleep 2. Explaining to families where Shafali Jeste, MD; physician the cutting-edge scientific David Geffen School of Medicine, understanding (based on the University of California, Organizer: latest cellular and genetic Los Angeles, California, USA Sanjeev V. Kothare, MD, FAAN, techniques) lies for a particular Evan Y. Snyder MD, PhD, FAAP FAASM; Cohen Children’s disorder and what novel Medical Center, diagnostic and therapeutic Lake Success, New York, USA options may lie ahead based on these understandings (new early tests, new drugs, new rehab strategies, etc.)

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 61 Wednesday, October 21 • continued

Evaluation of Nocturnal Events: Learning Objectives: 3:30 PM – 5:45 PM Seizures, Parasomnias and More 1. Identify potential challenges SYMPOSIUM: EPILEPSY: Sanjeev V. Kothare, MD, FAAN, to the current definition of Epilepsy and Psychiatric FAASM cerebral palsy from a variety of Comorbidities perspectives Evaluation of a Sleepy Child 2. Identify more clearly children Course Description: Joseph Kaleyias, MD, PhD; with and without cerebral This educational symposium East Sussex Healthcare palsy and those that that do has the objective to review the NHS Trust, Eastbourne, not fit clearly into an either-or main psychiatric and behaviour East Sussex, England, UK dichotomy disorders in children with epilepsy. Importantly, the symposium Evaluation of Sleep in Impact Statements: will focus on the difficulties of Neurodevelopmental Disorders 1. To accurately diagnosing diagnosis and optimal management Joanna Wrede, MD; cerebral palsy of ADHD, anxiety and depression in Seattle Children’s Hospital, 2. Counselling families about what a children with epilepsy. University of Washington, diagnosis of cerebral means and Seattle, Washington, USA does not mean for their child Learning Objectives: 1. Understand the difficulties Sleep Pharmacology in Organizer: and the auxiliary tests for the Pediatric Insomnia Michael Shevell, MDCM, FRCP, diagnosis of ADHD, depression Ann Marie Morse, DO; FCAHS; McGill University, and anxiety in children with Geisinger Commonwealth Montreal Children’s Hospital, epilepsy; School of Medicine, Geisinger, Montreal, Quebec, Canada 2. Understand the optimal Commonwealth School of Medicine, management of psychiatric and Geisinger Medical Center, The History of the Definition behaviour disorders in children Janet Weis Children’s Hospital, of Cerebral Palsy & with epilepsy. Danville, Pennsylvania, USA Epidemiologic Considerations Michael Shevell, MDCM, FRCP, Impact Statements: FCAHS 1. The diagnosis of ADHD, 3:30 PM – 5:45 PM depression and anxiety in SYMPOSIUM: CEREBRAL PALSY: The Emergence of Genomics children with epilepsy. An Open Discussion on the in Cerebral Palsy and Its 2. The optimal management of Definition of Cerebral Palsy Potential Impact on Definition ADHD, depression and anxiety in Michael Kruer MD; children with epilepsy. Course Description: Barrow Neurological Institute, Participants will gain an awareness Phoenix Children’s Hospital, Organizer: of the historical evolution of Phoenix, Arizona, USA Ana Carolina Coan, MD, PhD, the definition of cerebral palsy Campinas University – UNICAMP, including the current (2007) Low Resource Settings and Campinas, SP, Brazil consensus definition. Potential Defining Cerebral Palsy amplification and clarification Gulam Khandakar, MBBS, MPH, Epilepsy in Children – of this definition suggesting DCH, PhD, FAFPHM; Beyond Seizure Control continuity will be presented from Central Queensland Hospital Marilisa Guerreiro, MD, PhD, the perspectives of epidemiology, and Health Service, Campinas University, genomics, health care limitations, Rockhampton, Australia Campinas, Brazil rehabilitation and the lifespan. This will frame an open discussion Rehabilitation, Lifespan, with parental input about what ICF Considerations in challenges may lie ahead in any Defining Cerebral Palsy modification of the established Annette Majnemer OT, PhD; definition. McGill University, Montreal, Quebec, Canada

62 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 How to Differentiate ADHD from its panel will have an open discussion Organizer: Mimics in Children with Epilepsy? to identify themes and practices Mahendra Moharir MD, MSc, FRACP; Stéphane Auvin, MD, PhD, that can be improved, barriers University of Toronto, Hôpital Universitaire Robert-Debré, that could be overcome from a The Hospital for Sick Children, Université de Paris, healthcare systems perspective Toronto, Ontario, Canada Paris, France and shared and implemented across international settings. The Acute Pediatric Neurology in Depression and Anxiety in discussion will highlight the need the Inpatient Setting across the Children with Epilepsy – for development of global networks Globe – Can One Size Fit All? How to Improve the Diagnosis? and collaborations to systematically Mahendra Moharir MD, MSc, FRACP Kette Valente, MD, PhD, harmonize clinical care pathways University of São Paulo, as well inform the potential for Acute Inpatient Pediatric São Paulo, Brazil research opportunities in common Neurology – The North American acute pediatric neurologic Academic Practice Perspective Management of Psychiatric and conditions. Craig A. Press, MD, PhD; Behavior Disorders in Children’s Hospital of Colorado, Children with Epilepsy Learning Objectives: University of Colorado School Kirsten A. Donald MD, PhD, 1. Explore and understand the of Medicine, University of Cape Town, approach to workup and Aurora, Colorado, USA Cape Town, South Africa treatment of three common acute neurologic conditions in Acute Inpatient Pediatric each of the following settings: Neurology – The Australian 6:00 PM – 8:15 PM 1) Resource-intense academic Managed Care Approach SYMPOSIUM: medical center, 2) a managed Mark MacKay, MBBS, PhD; GLOBAL NEUROLOGY: care non-North American but Royal Children’s Hospital, Global Challenges and developed academic center Melbourne, Australia Opportunities in Inpatient setting, and 3) Developing Child Neurology Nation with limited resources Acute Inpatient Pediatric 2. Conceptualize how to provide Neurology in the Developing Course Description: high-quality, research-informed World – Advancing Care The objective of this symposium care depending on the resources with Limited Resources is to highlight and understand the available in each individual’s Vrajesh Udani, MD; reasons behind the differences setting. Hinduja National Hospital & in management of commonly Medical Research Centre, encountered pediatric neurological Impact Statements: Mumbai, India conditions across the globe. 1. The resources I have available Discussants from three diverse to investigate, diagnose and Panel Discussion and Q & A settings (a resource-intense manage status epilepticus. US academic medical center, 2. The resources I have available a managed care non-North to investigate, diagnose and American but developed academic manage anti-NMDA receptor center setting, and a developing encephalitis. nation with limited resources) 3. The resources I have available will compare and contrast their to investigate, diagnose and approach to three common acute manage acute arterial ischemic neurologic conditions: status stroke. epilepticus, anti-NMDA receptor encephalitis, and stroke. After each discussant comments on the evaluation, diagnosis, and management of each condition, the

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 63 Wednesday, October 21 • continued

6:00 PM – 8:15 PM of ketogenic diet and its variants Organizer: SYMPOSIUM: EPILEPSY: in epilepsy and other neurological Suvasini Sharma, MD, DM; Ketogenic Diets in Child disorders in children. The Lady Hardinge Medical College Neurology – A Tale of 100 Years: symposium will cover the recently and Associated Kalawati Saran What Does the Future Hold? published International consensus Children’s Hospital, guidelines, the use of the diet in New Delhi, India Course Description: genetic and metabolic epilepsies, As ketogenic diet completes use in neurological disorders other Dietary Therapy at a Century: a century of its use in child than epilepsy, and new insights into From Popularity to Obscurity neurology, this symposium the mechanism of action of the and Back Again proposal will summarize the current diet and implications for clinical Eric H. W. Kossoff, MD; and future perspectives of the use utilization. Johns Hopkins Hospital, of ketogenic diet and its variants Baltimore, Maryland, USA in epilepsy and other neurological Learning Objectives: disorders in children. The 1. Be aware of the recent Ketogenic Diet in Genetic symposium will cover the recently international consensus and Metabolic Epilepsies published International consensus guidelines on the use of KD, and Puneet Jain, MD, DM; guidelines, the use of the diet in its uses in metabolic and genetic The Hospital for Sick Children genetic and metabolic epilepsies, epilepsies and non-epilepsy Toronto, Ontario, Canada use in neurological disorders other neurodevelopmental conditions than epilepsy, and new insights into in children. New Insights into the the mechanism of action of the 2. Understand the current thinking Mechanisms of Action and diet and implications for clinical on the mechanisms of action Implications for Utilization utilization. The speakers include of the diet, and how we can Helen Cross, MB, ChB, PhD; Dr Eric Kossoff (USA), Dr Helen potentially use this to optimize University College London, Cross (UK), Dr Hoon-Chul Kang patient outcomes. Great Ormond Street (South Korea) and Dr Suvasini Impact Statements: Institute of Child Health, Sharma (India). As ketogenic diet 1. Early identification of childhood London, UK completes a century of its use in neurological conditions which child neurology, this symposium are likely to respond to the Non-epilepsy Uses and Other proposal will summarize the current ketogenic diet. Benefits of the Ketogenic Diet and future perspectives of the use 2. Awareness of the new Suvasini Sharma, MD, DM International consensus guidelines for the use of ketogenic diet in children with epilepsy.

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16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress

49th AnnualImpact Child Statements: Neurology Society Meeting10:30 AM – 12:45 PM Thursday, October 22 1. The recognition of SYMPOSIUM: neurometabolic disorders NEONATAL NEUROLOGY: 6:00 AM – 6:55 AM 2. The interpretation of metabolic Neurodevelopmental Outcomes LINDA DE MEIRLEIR test results in Congenital Heart Disease: NEUROMETABOLIC From Fetal Pathogenesis AWARD LECTURE: to Prevention Update in Pediatric 7:00 AM – 7:55 AM Neurometabolic Disorders 2020 HOWER AWARD LECTURE: Course Description: Lance Rodan, MD, FRCP(C); Migraine, Vertigo, and Dizziness This symposium will bring Boston Children’s Hospital, Kenneth J. Mack, MD, PhD; participants up-to-date on the Harvard Medical School, Mayo Clinic, critical role of fetal risk factors for Boston, Massachusetts, USA Rochester, Minnesota, USA neurodevelopmental disabilities arising from congenital heart Course Description: Course Description: disease including the key • Discussion of metabolic disease This session will help attendees contributions of chronic fetal discovery in the post-genomic to identify changes they could hypoxemia and maternal-fetal era: what are the tools we have? make in their practice related to stress. Emerging insights from fetal • Discussion of metabolic pathway addressing the multiple target and neonatal human imaging and analysis in the discovery of symptoms of migraine, which experimental models will define future disease modifying include dizziness and vertigo. the impact of fetal hypoxemia therapies. on brain growth and neuronal • Illustrative examples, through Learning Objectives: dysmaturation. We will explore review of recently described 1. Better organize the components emerging potential interventions neurometabolic disorders, of the migraine attack ranging from maternal-fetal including a novel disorder of 2. Understand the multiple forms hyperoxygenation to early life cerebral folate metabolism of vertigo and dizziness that environmental enrichment. and a disorder of polyamine patients experience metabolism, among others. Learning Objectives: Impact Statements: 1. Recognize the spectrum of Learning Objectives: 1. Addressing the multiple target neurodevelopmental disabilities 1. Identify a number of recently symptoms of migraine, which associated with various forms described neurometabolic include dizziness and vertigo of congenital heart disease and disorders their key fetal and neonatal 2. Become familiar with currently neuroimaging findings. available clinical tests that can 2. Recognize the relative impact aid in the diagnosis of rare of pre- and postnatal factors, neurometabolic disorders including maternal-fetal stress and chronic in utero hypoxemia on long-term neurodevelopmental outcomes associated with various forms of congenital heart disease

66 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Impact Statements: 10:30 AM – 12:45 PM real impact of those interventions. 1. Counselling parents on risks for SYMPOSIUM: In this symposium we aim: adverse neurodevelopmental NEURODEVELOPMENTAL • To present an update on outcomes associated with DISORDERS: therapeutic alternatives, beyond various forms of congenital heart IN SPANISH: Beyond pharmacological interventions, disease. Pharmacological Treatment for for treating neurodevelopmental 2. The indications and Neurodevelopmental Disorders: disorders like ADHD, ASD and interpretation of fetal or What Parents and Physicians learning disabilities neonatal imaging for patients Want to Know About the • To discuss the evidence base with various forms of congenital Available Options available about the benefits of heart disease. those interventions Course Description: • To present a clinical model for Organizer: Neurodevelopmental disorders the care of neurodevelopmental Stephen A. Back, MD, PhD, such as ADHD, ASD and learning disorders that can be adapted Oregon Health & Science University, disabilities are the most common by practitioners, worldwide. Portland, Oregon, USA cause of consultation in Pediatric Neurology in all countries. While Learning Objectives: Pathogenetic Mechanisms pharmacological treatment has 1. Learn how to evaluate and of Hypoxia-mediated been extensively studied, in some recommend common non- Cerebral Dysmaturation conditions like ADHD, the access pharmacological interventions Stephen A. Back, MD, PhD to stimulant medications in many and technology aids as part of countries is very limited and with the treatment of patients with Fetal Oxygenation in Utero very selective options. In addition, neurodevelopmental disorders. of Human Fetuses with the high cost of medications makes 2. Learn how to develop Congenital Heart Disease them of inaccessible for many programs to provide Mette Høj Lauridsen, MD, PhD; populations around the world. In comprehensive evaluation and Aarhus University Hospital, other conditions, like ASD and treatment for patients with Aarhus, Denmark LD, the benefits of medications neurodevelopmental conditions are more controversial. Non- that decrease the long-term Advanced Brain Imaging – pharmacological and alternative impact on their mental and From Fetus to Neonate with interventions have been used physical health as they grow up. Congenital Heart Disease extensively around the world Serena J. Counsell, PhD; without clear evidence of the Impact Statements: King’s College London, benefits that they can provide 1. The use of some common non- London, UK to patients and families. Some of pharmacological interventions these alternative interventions and alternative therapies in Where to Next: Potential are more expensive and have side Neurodevelopment disorders, Interventions from the effects that are often not disclosed. especially Autism. Fetus to the Environment Parents have strongly advocated 2. How to coordinate chronic and Steven Paul Miller, MDCM, MAS, for research to demonstrate the long-term care for patients with FRCPC; The Hospital for Sick neurodevelopment disorders, Children, The University of Toronto, especially ADHD. Toronto, Ontario, Canada

TOGETHER•APART virtual OCTOBER 12-23,2020 2020

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 67 Thursday, October 22 • continued

Organizer: 1:00 PM – 3:15 PM Obstacles to Practice Humanism in Maria Teresa Acosta, MD; SYMPOSIUM: ETHICS: Child Neurology in Global Health National Human Genome HUMANISM IN CHILD Ornella Ciccone; MD, DTM&H, MMED; Research Institute, National NEUROLOGY: The Time is Now! University Teaching Hospital, Institutes of Health, Lusaka, Zambia Bethesda, Maryland, USA Course Description: Goal: The primary goal of this Neurology and Longevity: Co-Organizer: symposium is to increase global A Critical Care Pediatrician’s Gabriel Gonzalez Rabelino, awareness about the importance Perspective University of the Republic of of humanism in child neurology for Kam Lun Ellis Hon; MBBS, MD, Uruguay, Pereira Rossell Hospital, our patients and for ourselves. FAAP, FCCM, The Hong Kong Montevideo, Uruguay Children’s Hospital, Secondary Goals: Hong Kong Why to Treat ADHD as a 1. Recognize the humanistic needs Chronic Medical Condition: of our patients with neurological The Time is Now! Impact of a Health Care Model disorders Humanism as the Global and Long-Term Outcomes 2. Understand how to live a Bedrock of Child Neurology Maria Teresa Acosta, MD humanistic professional life while David L. Coulter, MD facing many challenges Alternative Therapies and 3. Learn what humanism means Non-Pharmacological Treatment in every continent and country 1:00 PM – 3:15 PM in Autism: What Parents throughout the world SYMPOSIUM: HEADACHE: Would Like to Know Migraine Management in 2020: Víctor Ruggieri, MD; Learning Objectives: New Options for Treatment Hospital de Pediatría J. P. Garrahan, 1. Understand the importance of and How to Incorporate Recent Buenos Aires, Argentina humanism in child neurology Guidelines and Novel Treatments 2. Understand what humanism in Clinical Practice Advances in the Use of means in different global Technology and Virtual settings Course Description: Reality for the Diagnosis and This session will cover recent Treatment of ASD and Other Impact Statements: developments in migraine Neurodevelopmental Disorders 1. Being more aware and supportive management. Dr. Lewis and Fernando Mulas Delgado, MD, PhD; of the humanism of my patients Dr. Oakley will review new Instituto Valenciano de and their families and more medications (including anti-GCRP Neurología Pediátrica, responsive to them medications) and neuromodulatory Valencia, Spain 2. Being more sensitive to the devices designed for the acute different meanings of humanism and preventive treatment of Treatment of in my patients who come from migraine. Speakers will discuss the Neurodevelopmental Disorders various cultural backgrounds mechanisms of action, evidence without Geographic Barriers of efficacy, potential side effects, Manuel Vides-Rosales, MD MS; Organizer: and pediatric specific issues Centro Medico Escalon, David L. Coulter, MD; for these novel treatments. Dr. San Salvador, San Salvador, Harvard Medical School, Guidetti will review recently El Salvador Boston Children’s Hospital, published guidelines for the Boston, Massachusetts, USA treatment of pediatric migraine and discuss how to integrate Definitions and History these recommendations into the of Humanism clinical practice treating youth Alcy R. Torres, MD; with chronic migraine. He will Boston University School of also consider similarities and Medicine, Boston Medical Center, differences between European and Boston, Massachusetts, USA US migraine treatment so we can each learn from others’ experience. Together these topics will enhance participants’ ability to manage episodic and chronic migraine in clinical practice.

68 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Learning Objectives: New Guidelines for Treatment Impact Statements: 1. Understand the role of CGRP of Pediatric Migraine: 1. Understanding the treatment in migraine and how anti-CGRP How to Apply These and care of a child before, during medications may be used to Recommendations and Novel and after gene transfer and the treat migraine. Treatments to Manage Chronic role of Newborn screening as 2. Understand and describe the Migraine in Clinical Practice therapies are approved. role of neuromodulation in the Vincenzo Guidetti, MD; 2. Understanding and describing management of migraine and University of Rome “La Sapienza,” risk/benefit considerations of how these devices may be used Rome, Italy gene replacement therapy in a to treat migraine in the pediatric non-progressive muscle disease population. such as X-linked myotubular 3. Discuss how the new AAN 3:30 PM – 5:45 PM myopathy. guidelines on the treatment SYMPOSIUM: of pediatric migraine can be NEUROMUSCULAR DISEASE: Organizer: applied to clinical practice. Gene Transfer for Children: Anne M. Connolly, MD, FAAN; What We Know Now Nationwide Children’s Hospital, Impact Statements: The Ohio State University 1. The management of chronic Course Description: College of Medicine, migraine in pediatrics. The promise of gene therapy is now Columbus, Ohio, USA 2. Acute or abortive treatment of a reality for several neuromuscular migraine in pediatrics. conditions. This symposium will Gene Therapy for SMA and DMD: address four educational objectives Where are we Now? Organizer: including 1)to understand treatment Anne M. Connolly, MD, FAAN Heidi K. Blume, MD, MPH; implementation for commercially Seattle Children’s Hospital, available gene transfer 2) to Gene Replacement Therapy in University of Washington, understand the status of ongoing X-linked Myotubular Myopathy Seattle, Washington, USA clinical trials in Spinal Muscular Nancy L. Kuntz, MD, FAAN; Atrophy, X-linked myotubular Ann & Robert H Lurie Novel Medications for the myopathy, Duchenne and limb Children’s Hospital of Chicago, Treatment of Migraine: girdle muscular dystrophy; 3) to Chicago, Illinois, USA Anti-GGRP Therapies and understand future gene therapy for Other Medications in the other neuromuscular disorders and Is Gene Replacement a Viable Migraine Pipeline 4) to understand the critical role of Option for my Favorite Disease? Kara Stuart Lewis, MD, FAHS, FAAN; Newborn screening if gene therapy Katherine D. Mathews, MD; Barrow Neurological Institute is to succeed. University of Iowa Carver at Phoenix Children’s Hospital, College of Medicine, Phoenix, Arizona, USA Learning Objectives: Iowa City, Iowa, USA 1. Understand the current status of Neuromodulation for Migraine: approved, ongoing, and future Newborn Screening in the What is the Role for Devices in the clinical gene transfer trials for Era of Gene Therapy Treatment of Childhood Migraine? children with neuromuscular Margie Ream, MD, PhD; Christopher B. Oakley, MD; disorders. Nationwide Children’s Hospital, Johns Hopkins Hospital, 2. Understand the role of the Columbus, Ohio, USA Baltimore, Maryland, USA Newborn Screening in the translation of these clinical trials to implementation across all populations.

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 69 Thursday, October 22 • continued

3:30 PM – 5:45 PM Finally, the symposia will address Organizer: SYMPOSIUM: EPILEPSY: current therapeutic options Jorge Vidaurre, MD; IN SPANISH: Pediatric Epilepsy. for children with drug resistant Nationwide Children’s Hospital, When Drugs Don’t Work epilepsy, when surgery is not an The Ohio State University, option. Target audience: Latin Columbus, Ohio, USA Course Description: America and Spanish speaking To present current data on drug countries, with the goal to raise Elia M. Pestana-Knight, DO; resistant epilepsy and therapeutic awareness about importance of Cleveland Clinic Epilepsy Center, options when pharmacological developing alternative therapies Cleveland, Ohio, USA treatment is not a choice. This (including surgery) for children program will explore latest with drug resistance epilepsy. Dr. Co-Organizer: information about pediatric Vanegas, from Mexico has been a Mario A. Genel Castillo, MD; epilepsy surgery. Speaker from leader and advocate in the initiative Clinica de Epilepsia, Cleveland Clinic, a center with of creating surgical centers in Latin Hospital de Salud Mental, extensive expertise in surgical America and is a representative of Tijuana B.C., Mexico epilepsy will present available ILAE (International League against surgical techniques and outcomes. Epilepsy). This symposium is also Introduction This will be followed by a intended to educate audience Jorge Vidaurre, MD discussion about the challenges about need to develop such experienced in Latin America for programs in poor resource regions. Pediatric Epilepsy Surgery the creation of surgical programs. in the Stereo EEG Era. Learning Objectives: Cleveland Clinic Experience 1. As a result of this educational Elia M. Pestana-Knight, DO session, participants will be able to: learn relevant data Epidemiology of Drug Resistant about pediatric drug refractory Epilepsy. Data You Should Know. epilepsy and understand that What to Tell our Families? medications are not the best Loreto Ríos-Pohl, MD; option. Clínica Integral de Epilepsia 2. As a result of this educational Infanto-Juvenil (CIEI), session, participants will be Santiago, Chile able to learn about importance of creating epilepsy surgery Establishing Epilepsy programs in Latin America Surgical Programs in to care for children with Low-income Countries. drug refractory epilepsy and The Latin America Experience alternative options when surgery Mario A. Alonso Vanegas MD, FAES; is not a possibility Internacional Epilepsy Surgery Center, HMG-Coyoacán Hospital, Impact Statements: México City, México 1. This educational session helped me to identify changes I could Drug Refractory Epilepsy. make in my practice related to When Surgery is not an Option patients who present to my clinic Juan Carlos Perez-Poveda, MD; with drug refractory epilepsy Pontificia Universidad Javeriana, 2. This educational session helped Hospital Universitario San Ignacio, me to identify changes I could Fundacion Hospital Pediatrico, make in my practice related Bogotá, D. C., Colombia to referral for epilepsy surgery evaluation in children with drug refractory epilepsy, who are appropriate candidates

70 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 6:00 PM – 8:15 PM Dr Sankhyan will be discussing Organizer: SYMPOSIUM: inherited and acquired neurological Suvasini Sharma, MD, DM; NEURO-METABOLIC DISORDERS: disorders responsive to vitamin B12 Lady Hardinge Medical College and Vitamin Responsive Conditions in and Folate treatment. There will be Associated Kalawati Child Neurology: What’s New? a special focus on infantile tremor Saran Children’s Hospital, syndrome, an interesting condition New Delhi, India Course Description: characterized by infantile onset Vitamin responsive conditions neuroregression, tremors, skin and Thiamine and Biotin are a “must know” area for every hair changes, which responds very Responsive Disorders child neurologist, as vitamin well to vitamin B12 therapy. Dr Suvasini Sharma, MD, DM treatments are simple, inexpensive Sharma will cover the recognition, and safe treatments for a host diagnosis and management of Pyridoxine Dependent of neurological conditions. Child inborn errors of metabolism which Epilepsy and Related Disorders: neurologists need to be able to respond to thiamine and biotin Recent Advances promptly recognize and treat these supplementation with special Ingrid Tein, MD; entities. In this session, the speakers focus on the recently described The Hospital for Sick Children, will discuss the latest developments biotin and thiamine responsive University of Toronto, in vitamin responsive epilepsies, basal ganglia disease, caused by Toronto, Ontario, Canada encephalopathies, movement mutations in the SLC19A3 gene. disorders and neuromuscular Acquired neurological disorders Riboflavin Responsive Disorders conditions. The four speakers caused by thiamine deficiency, such Haluk Topaloğlu, MD; will be Dr Ingrid Tein (Canada), as Wernicke encephalopathy will Hacettepe Children’s Hospital, Dr Haluk Topaloglu (Turkey), Dr also be discussed. Ankara, Turkey Naveen Sankhyan (India) and Dr Suvasini Sharma (India). Learning Objectives: Vitamin B12 and Folate Responsive Dr Tein’s lecture will be focused on 1. Recognize common as well as Disorders vitamin responsive early infantile rare and newly described vitamin Naveen Sankhyan, MD, DM; epileptic encephalopathies with responsive conditions in child Post Graduate Institute of special reference to pyridoxine neurology. Medical education and Research, dependent epilepsy and related 2. Understand the diagnostic Chandigarh, India disorders. The current guidelines approach and treatment on recognition and treatment of strategies. these conditions as well as the new genetic conditions now recognized Impact Statements: to causing pyridoxine dependent 1. Trial of high dose riboflavin epilepsy will be discussed. Dr supplementation unexplained Topaloglu will discuss riboflavin progressive peripheral and responsive conditions with special cranial neuropathies and emphasis on riboflavin transporter neuronopathies deficiency. The recent advances in 2. Vitamin trials in unexplained clinical and genetic diagnosis and refractory seizures in young treatment strategies for riboflavin infants, and high dose vitamin responsive disorders will be trials in acute metabolic discussed. decompensations.

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 71 Thursday, October 22 • continued

6:00 PM – 8:15 PM Learning Objectives: Introduction: A Global SYMPOSIUM: 1. Learn about the global situation Perspective of Child Neurology GLOBAL NEUROLOGY: of pediatric neurology and Agustin Legido, MD, PHD, MBA Pediatric Neurology. understand the situation of Jorge Vidaurre, MD A Global Perspective pediatric neurology practice in low income countries. Child Neurology in Africa. Course Description: 2. Learn about importance of Narrowing the Gap in Access To educate audience about the collaborative international to Medical Care global situation of pediatric projects directed to improve Jo M. Wilmshurst, MB, BS, MD, neurology, using data and statistics education and clinical care in low Red Cross War Memorial from the World Health Organization income countries. Children’s Hospital, University (WHO).The program brings of Cape Town, Cape Town, international leaders and speakers Impact Statements: Western Cape, South Africa with extensive experience in 1. Learning about the global international outreach/collaborative situation of pediatric neurology Yes. There are Global projects directed to reduce and becoming more active Disparities in Epilepsy Care. gap in medical knowledge and in supporting international Can we do Something? access to neurological care. The educational programs Solomon L. Moshé, MD; symposium will educate audience 2. Recognizing importance of t Albert Einstein College of Medicine, about importance of collaborative international outreach programs Montefiore Medical Center, efforts between medical societies directed to improve pediatric Bronx, New York, USA (including CNS), to support local neurological care, and finding efforts in low income countries. ways to collaborate, as a CNS Practicing Pediatric Neurology member in Poor Resource Regions. The panel of speakers (which Importance of Collaborative Efforts includes current president of the Organizer: Arushi G. Saini, MD, DM; international Child Neurology Jorge Vidaurre, MD; Postgraduate Institute of Medical Association and past president of Nationwide Children’s Hospital, Education and Research (PGIMER), the international League against The Ohio State University, Chandigarh, India Epilepsy) will share their wide Columbus, Ohio, USA experience working with poor- resource regions in Africa and other Co-Organizer: poor-resource regions and will Agustin Legido, MD, PHD, MBA; educate audience with potential Philadelphia, Pennsylvania, USA solutions to improve access to neurological care for children living in these areas.

72 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Spencer, living with epilepsy Connecting with patients

At UCB, everything we do starts with a simple question: “How will this create value for people living with severe diseases?” UCB is proud to support the Child Neurology Society. We are committed to advancing research to improve the lives of people living with epilepsy and finding solutions to help patients live at their ideal. Contact ucbCARES® for additional information about UCB products, patient resources, and financial assistance at 1-844-599-CARE (2273) or [email protected].

To learn more, visit www.ucb-usa.com www.askucbCARES.com © 2020 UCB, Inc. All rights reserved. ICNA • CNS ICNA • CNS

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress

49th Annual10:30 AM Child – 12:45 Neurology PM Society Meetingvisits, hospitalizations, and deaths, Friday, October 23 SYMPOSIUM: and recent data shows that ver 25% TRAUMATIC BRAIN INJURY: of fall-related TBIs were among the 6:00 AM – 6:55 AM New Advances in Management, youngest (0-4 years). FRANK FORD AWARD LECTURE: Treatment and Rehabilitation The Global Burden of Paediatric Goal: The main objective of Neurological Disorders Course Description: this symposium is to increase Charles Newton, MD; Each year, TBI causes a substantial awareness about importance University of Oxford, Oxford, number of deaths and leads of practicing humanism in child United Kingdom, KEMRI-Wellcome to life-long disability for many neurology not only for our patients Trust Collaborative Programme, children around the world. Every but for ourselves. Kilifi, Kenya year, 830,000 children die from unintentional or “accidental” Secondary Goals: Course Description: injuries and TBI represents about 1. Recognize the humanistic needs An invited lecture that assess 30%. 2270 children die every day of our patients with neurological the global burden of Pediatric as a result of an unintentional injury diseases Neurology Disorders, discussing and the vast majority of these 2. Understand how to live a disability adjusted life years injuries occur in low-income and humanistic professional life middle-income countries. facing so many challenges Learning Objectives: 3. Be familiar with difficult 1. Meaning of the Disability Child injuries are a growing global situations and how to solve them Adjusted Life Years in terms of public health problem. They are a in current times and different Global Burden of Diseases significant area of concern from areas of the world. 2. Identify the neurological the age of one year. Among older complications of diseases children they represent almost Learning Objectives: usually associated with low half of the deaths. The effects of 1. Recognize the symptoms income countries and immigrant a TBI can vary significantly, but of patients with mild or populations individuals with a moderate or severe Traumatic Brain Injury severe TBI may have long-term or and design comprehensive Impact Statements: life-long effects from the injury. therapeutic plans for each group 1. Make Pediatric Neurologists A severe TBI not only impacts the according to their needs more aware of neurological life of an individual and their family, 2. Implement timely, appropriate conditions in low income but it also has a large societal supportive critical care, countries and immigrant and economic toll. The lifetime neurological therapy and populations economic cost of TBI, including rehabilitation for patients with 2. Introduce cultural awareness of direct and indirect medical costs, traumatic brain injury neurological conditions in the was estimated to be approximately immigrant populations. $76.5 billion in 2010 is the US only. Impact Statements: 1. Diagnosis and management Additionally, the cost of fatal TBIs of children with mild or severe and TBIs requiring hospitalization, traumatic brain injury many of which are severe, account 2. Rehabilitation of children with for approximately 90% of total TBI traumatic brain injury with long medical costs. Falls are one of the term sequelae leading causes of TBI-related ED

74 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 Organizer & Moderator: Impact Statements: 1:00 PM – 3:15 PM Christopher C. Giza, MD; 1. The recognition of SYMPOSIUM: UCLA – Mattel Children’s Hospital, clinical features of certain NEUROIMMUNOLOGY: MOG Los Angeles, California, USA rare neurogenetic and Antibody Associated neurometabolic diseases. Neurological Disease – Co-Organizer: 2. Knowledge about recent An Update for the Clinician Alcy Torres, MD; advances in the treatment Boston University School of of neurogenetic and Course Description: Medicine, Boston Medical Center, neurometabolic diseases. This symposium’s objective is Boston, Massachusetts, USA to update the child neurology Organizer: community on the emerging and Basic Science and Translational Wang-Tso Lee, MD, PhD, rapidly expanding spectrum of Research Relating to Pediatric TBI National Taiwan University MOG AB associated neurological Christopher C. Giza, MD Children’s Hospital, disease. This would be Taipei, Taiwan predominantly clinician-centric Pediatric Concussion and Mild TBI and would help the participants Alcy Torres, MD Recent Advances in SSADH in getting updated information Deficiency, a Disorder of on the diagnostic and therapeutic Severe TBI: Evaluation and GABA Metabolism challenges the clinician faces in Managing of Children in the ICU Phillip L. Pearl, MD; taking care of this newly described Biju Hameed, MRCPI, MRCPCH, Boston Children’s Hospital, inflammatory demyelination PhD; Great Ormond Street Harvard Medical School, disorder (IDD) of the central Hospital for Children, Boston, Massachusetts, USA nervous system with myriad London, England, UK presentations. Recent Advance in Possible Innovative and Practical Probiotic Treatment for Learning Objectives: Methods of Rehabilitation Neurogenetic Disorders 1. Identify the different clinical Lucia Braga, Neuroscientist, PhD; Wang-Tso Lee, MD, PhD situations where one should SARAH Network of consider MOG antibody Rehabilitation Hospitals, Gene Therapy for AADC Deficiency associated neurological diseases Brasilia, Brazil and other Neurogenetic Disorders in the clinic and in the ICU. Toni Pearson, MBBS, Washington 2. Familiarize themselves with the University School of Medicine, imaging features that distinguish 10:30 AM – 12:45 PM St. Louis, Missouri, USA MOG AB associated IDDs from SYMPOSIUM: AQP-4 associated NMOSD NEUROMETABOLIC DISORDERS: Recent Advance in Targeted and from MS and learn how Novel Advanced Treatment in Treatment in Children with NCLs to differentiate these different Neurogenetic Disorders Nicola Specchio, MD, PhD, syndromes Bambino Gesu’ Children’s Hospital, 3. Learn about the challenges of Course Description: IRCCS, Rome, Italy the detection of MOG ABs and The aim of this symposium is also gat an overview of how to present novel treatments for these antibodies cause disease. neurogenetic disorders, which will 4. Decide the why, when and how enhance our understanding of the to manage these disorders n the future potential for treatment of a acute stage and in the long-term. range of neurogenetic conditions. 5. Give long-term prognosis to parents about risk of relapse and Learning Objectives: any persisting deficits expected. 1. Learn the pathogenic mechanisms of some important neurogenetic and neurometabolic diseases in children. 2. Gain knowledge about recent advances in novel treatments for TOGETHER•APART some important neurogenetic and neurometabolic diseases. virtual OCTOBER 12-23,2020 2020

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 75 Friday, October 23 • continued

Impact Statements: 1:00 PM – 3:15 PM Impact Statements: 1. Diagnosis and differential SYMPOSIUM: 1. Various mechanisms of diagnosis of MOG – associated GLOBAL NEUROLOGY: involvement to provide Neurological Disorders Integration of Global Health effective support for child 2. Treatment strategies in the and Child Neurology: neurology practices in lower different MOG associated Perspectives and Successful resource regions through disorders. Partnerships Around the World global partnerships 2. Developing strategies Organizer: Course Description: to establish successful Vrajesh Udani, MD; In this symposium, we highlight partnerships in the Hinduja Hospital & Medical the ways for participants to developing world for research Research Centre, successfully partner with collaborations Mumbai, India institutions around the world in order to integrate global health Organizer: Overview of the MOG Antibody into child neurology practices. Archana A. Patel, MD, MPH; Associated IDDs and Challenges The objectives include: Harvard Medical School, in Laboratory Diagnosis 1. Discuss various mechanisms Boston Children’s Hospital, Vrajesh Udani, MD and levels of involvement Boston, Massachusetts, USA possible for child neurologists, Clinical and Imaging Features including opportunities for Integrating Global Health of the MOG Associated IDDs those in training and early in a Child Neurology Career Russell Dale, MRCP, PhD; career phases, Archana A. Patel, MD, MPH Children’s Hospital at Westmead, 2. Identifying mechanisms University of Sydney, of involvement for child How to Get Started – Clinical and Sydney, NSW, Australia neurologists based in Educational Opportunities higher resourced settings to in Global Child Neurology Update on Current Management partner with civil and NGO Douglas G. Postels, MD, MS; Strategies and Outcome in the organizations in the developing Children’s National Medical MOG Associated IDDs world with a primary Center, George Washington Yael Hacohen, MD; educational or clinical focus, University, Washington, DC, USA Great Ormond Street 3. Understand the perspectives Hospital for Children, of researchers in the Building a Research London, United Kingdom developing world in order Collaboration- Considerations to build successful research and Perspectives Panel Discussion – collaborations, and 4. of Researchers from LMIC Case Scenarios Providing an example of Pauline Samia, Mphil; Neelu Desai, MD, DNB; approaching research in global Aga Khan University, PD Hinduja Hospital & child neurology, including East Africa, Nairobi, Kenya Medical Research Centre, mechanisms for funding and Mumbai, India partnership. Building a Research Collaboration- Considerations for Learning Objectives: Funding and an Example from 1. Identify opportunities for the US and Nigeria getting involved in global child Edwin Trevathan, MD, MPH; neurology Vanderbilt University 2. Understand the core Medical Center, components of successful Nashville, Tennessee, USA global research collaborations, including engagement, support for researchers in the developing world, and funding strategies

76 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 B:9" T:8.5" S:7.625"

My  rst seizure could have been trying to tell you something. S:10.375" B:11.5" When the  rst seizure strikes a newborn, be aware of T:11" and consider testing for molybdenum cofactor de ciency (MoCD).1 This neurological disease can present with intractable seizures and trigger a pattern of progressive brain damage that is often fatal.1-3

Every minute counts, so use the STAT approach to make an early treatment decision:

S See a seizure?

T Think MoCD.

A Assess for sulfites.

T Time to call Origin Biosciences.

Contact Origin Biosciences at (617) 322-5165 to learn about an investigational treatment for MoCD Type A.

Origin Biosciences is a member of the BridgeBio family. References: 1. Mechler K et al. Genet Med. 2015;17(12):965-970. 2. Schwahn BC et al. Lancet. ©2019 Origin Biosciences. All rights reserved. PRC-““” “•/—• 2015;386(10007):1955-1963. 3. Atwal PS et al. Mol Genet Metab. 2016;117(1):1-4.

11408286_Origin_CNS_STAT Journal Ad Resize_M2FR.indd 1 9/21/20 4:31 PM PREPARED BY 11408286 Origin CNS STAT Journal Ad - Resize M2FR Job info Images Fonts Special Instructions Date: 9-21-2020 4:30 PM NY_ORIG_A054189_4C.tif (CMYK; 816 ppi; Gotham Rounded (Bold), Meta Pro (Condensed None Client: BridgeBio Pharma 36.76%; 644.7MB), Origin_Inline_FullCol- Normal, Condensed Bold, Condensed Normal Product: Origin Biosciences-Nulibry or_CMYK.ai (9.64%; 1.1MB) Italic, Condensed Book, Bold) Client Code: None Additional Information WF Issue # None None Releasing as: PDFx1A X1A_ Final Size: None Finishing: None Gutter: None Inks Additional Comments for Sizing Colors: 4C Cyan, Magenta, Yellow, Black None Team Producer: None AD: Victoria Rompilla-Vecchione AE: Andrea Stello Scale: 1" = 1" QC: None Bleed 9" w x 11.5" h 9" w x 11.5" h Production: Debi Post Trim/Flat 8.5" w x 11" h 8.5" w x 11" h Digital Artist: Schlomann, Greg (PPY-FCR) Live/Safety 7.625" w x 10.375" h 7.625" w x 10.375" h FR Spellcheck: None

Path: PrePress:BridgeBio:Origin:11408286:11408286_Origin_CNS_STAT Journal Ad Resize_M2FR.indd ICNA • CNS ICNA • CNS Sponsor/Exhibitors ICNA and CNS thank the following partners

16th International Child Neurology Congress for their generous financial support. 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting GOLD SPONSORS

SILVER SPONSORS

recode for life™

BRONZE SPONSORS

Aeglea BioTherapeutics European Paediatric National Institute of Sanford Health Aquestive Therapeutics Neurology Society Neurological Disorders Sarepta Therapeutics (EPNS) and Stroke (NINDS) Association of Child St. Luke’s University Neurology Nurses Invitae Origin Biosciences Health Network (ACNN) Lineagen Orphazyme Medical Tourette Association AveXis Medical Affairs LivaNova Affairs of America BioMarin Marinus Parent Project UT Health Austin Pharmaceutical Inc. Pharmaceuticals, Inc. Muscular Dystrophy Pediatric Neurosciences RosmanSearch at Dell Children’s Saint Francis Variantyx Health System

78 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 ICNA • CNS ICNA • CNS Schedule at a Glance

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting ALL TIMES PACIFIC DAYLIGHT TIME 15 Minutes Q&A Will be Added to Each CME Session (other than plenary/award lectures – no Q&A)

Monday, October 12, 2020 On Demand (24/7) Welcome: Jo Wilmshurst, President, ICNA On Demand (24/7) Welcome: Phillip Pearl, President, CNS On Demand (24/7) Welcome: Jonathan Mink, Chair, Joint CNS-ICNA Program Planning Committee 1:00 PM – 2:00 PM Professors of Child Neurology (PCN): Part 1: Annual Business Meeting (Private Zoom Meeting) 2:15 PM - 4:30 PM Professors of Child Neurology (PCN): Part II: Education Session (Private Zoom Meeting) 2:30 PM – 4:00 PM Cerebral Palsy SIG 4:30 PM – 6:00 PM Telemedicine SIG 4:30 PM – 6:00 PM Neurodevelopmental Disorders SIG On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word) Tuesday, October 13, 2020 11:30 AM – 12:30 PM Industry Sponsored Product Theater: Spinal Muscular Atrophy (Genentech) 1:00 PM - 2:00 PM Industry Sponsored Educational Seminar: Patient Identification, Evaluation, and Management – Addressing Multiple Challenges in Neurodegenerative Lysosomal Storage Diseases (Takeda) 1:00 PM – 3:00 PM Meet the Experts: Experimental Therapeutics; Gene Therapy for Childhood Neurological Disorders 3:00 PM – 4:30 PM Education SIG 3:30 PM – 5:30 PM Workshop: Neuropsychiatry/Movement Disorders: Practical Management of Functional Neurologic Diseases in Children 6:00 PM – 8:00 PM Meet the Experts: Ethics: Costly Drugs and Healthcare – Ethics and Value Perspectives from Different Healthcare Systems 6:00 PM – 8:00 PM Meet the Experts: Neuroimmunology: Parainfections and Seronegative Autoimmune Encephalitis in Children: Updates and Controversies 6:00 PM – 8:00 PM Seminar: Epilepsy: Don’t Ask Don’t Tell, or Full Disclosure? Discussing SUDEP with Patients and Families in the Global Community On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word)

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 79 Schedule at a Glance ALL TIMES PACIFIC DAYLIGHT TIME 15 Minutes Q&A Will be Added to Each CME Session (other than plenary/award lectures – no Q&A)

Wednesday, October 14, 2020 8:00 AM – 10:00 AM Seminar: Neuroinfectious Disease: Measles Vaccination – Current Situation and Consequences – A Global Perspective 8:00 AM – 10:00 AM Seminar: Stroke: Pediatric Stroke in the Era of Advanced Genetics 10:00 AM – 12:00 PM Workshop: Epilepsy: Pediatric Epilepsy Surgery: When, by Whom, and What to Expect? 10:30 AM – 12:30 PM Seminar: Neurogenetics: Recent Advances in the Etiologies and Mechanisms Underlying Common Brain Malformations 12:30 PM – 1:30 PM Industry Sponsored Educational Seminar: Distinguishing Pediatric Movement Disorders: Uncovering AADC Deficiency (PTCBio) 1:00 PM – 3:00 PM Seminar 4: Neuroimmunology: A New Era for Patients with NMOSD, including Children 3:00 PM – 4:30 PM Early Stage Investigator SIG 3:00 PM – 4:30 PM Neurogenetics SIG 4:00 PM – 6:00 PM Industry Sponsored CME Seminar: SMA Horizons: What is the Future of SMA Management? (Genentech) 6:00 PM – 8:00 PM Junior Member Seminar: Becoming a Physician Scientist in Pediatric Neurology On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word) Thursday, October 15, 2020 10:30 AM - 11:30 AM Industry Sponsored Product Theater: Spinal Muscular Atrophy (Avexis) 10:30 AM – 12:30 PM Workshop: Global Neurology: Training to Bridge the Gap in Global Access to Child Neurology Care 12:30 PM – 2:00 PM Peds Demyelinating Disease SIG 12:30 PM – 2:30 PM Industry Sponsored CME Seminar: Developmental and Epileptic Encephalopathies (Zogenix) 1:00 PM – 3:00 PM Junior Member Seminar: Nurturing the Global Pipeline of Academic Child Neurologists 3:30 PM – 5:30 PM Meet the Experts: Behavioral Neurology: Management of Behavior in Children with Neurodevelopmental Disorders 6:00 PM – 8:00 PM Meet the Experts: Neurometabolic Disorders: Unravelling the Complexity of Treatable Neurometabolic Disorders: A Case-based Session On Demand (24/7) Posters & Video Posters On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word)

80 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 ALL TIMES PACIFIC DAYLIGHT TIME 15 Minutes Q&A Will be Added to Each CME Session (other than plenary/award lectures – no Q&A)

Friday, October 16, 2020 8:00 AM – 10:00 AM Meet the Experts: Neuro-Cutaneous Disorders (In Spanish): Neurocutaneous Syndrome Iberoamerican Network 10:00 AM - 11:00 AM Industry Sponsored Product Theater: The Evolving Role of Early Pediatric Care for Spinal Muscular Atrophy (SMA) and a Treatment for Presymptomatic and Early-onset SMA (Biogen) 10:30 AM – 12:30 PM Seminar: Headache (In Spanish): Migraine in Children and Adolescents – Diagnosis, Management and Treatment 10:30 AM – 12:30 PM Seminar: Neuroinflammation: Interferonopathies 10:30 AM – 12:30 PM Seminar: Neonatal Neurology: The Value of Magnetic Resonance Imaging in the Newborn 10:30 AM – 12:30 PM Meet the Experts: Neuromuscular: The Many Faces of Pediatric Neuromuscular Diseases: Cases, Approaches, Pearls and Challenges 12:30 PM – 2:00 PM Neuro-Oncology SIG 12:30 PM – 2:00 PM Neonatal Neurology SIG 1:00 PM – 3:00 PM Workshop: Epilepsy/General Child Neurology: Telehealth – A Means to Global Outreach 3:30 PM – 5:30 PM Junior Member Seminar: International Clinical Research Consortia in Child Neurology: Get Involved! 3:30 PM – 5:30 PM Child Neurology Foundation: Shortening the Diagnostic Odyssey in Children with Neurologic Conditions 3:30 PM – 5:30 PM Meet the Experts: Movement Disorders: Tics, Stereotypies, and their Look-a-Likes – Understanding and Managing Repetitive Movements 6:00 PM – 8:00 PM Junior Member Seminar: Choosing your Career Track – Academic, Private Practice, and NGOs On Demand (24/7) Posters & Video Posters On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word) Monday, October 19, 2020 7:00 AM – 3:30 PM Neurobiology of Disease in Children Symposium: Traumatic Brain Injury (TBI) 12:30 PM – 1:30 PM Industry Sponsored Educational Seminar: Distinguishing Pediatric Movement Disorders: Uncovering AADC Deficiency (PTCBio) 2:30 PM – 4:00 PM Cerebral Palsy SIG 5:00 PM – 6:00 PM Industry Sponsored Product Theater: Spinal Muscular Atrophy (Genentech) On Demand (24/7) Posters & Video Posters On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word)

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 81 Schedule at a Glance

ALL TIMES PACIFIC DAYLIGHT TIME 15 Minutes Q&A Will be Added to Each CME Session (other than plenary/award lectures – no Q&A)

Tuesday, October 20, 2020 6:00 AM – 6:55 AM JOHN STOBO PRITCHARD AWARD LECTURE: Nicola Specchio, MD, PhD, Bambino Gesu’ Children’s Hospital, IRCCS, Rome, Italy: Developmental and Epileptic Encephalopathies: What We Know and What We Do Not Know 7:00 AM – 7:55 AM BERNARD SACHS AWARD LECTURE: Joseph G. Gleeson, MD; University of California San Diego, Rady Children’s Institute for Genomic Medicine, San Diego, CA, USA: Genes as a Window into the Developing Brain 8:00 AM – 9:00 AM Industry Sponsored Educational Seminar: Progressive Pathways: Recent Recommendations and Emerging Therapies for Treatment of Tumors Associated with Neurofibromatosis Type 1 in Children (AstraZeneca) 10:30 AM - 11:30 AM Industry Sponsored Product Theater: Spinal Muscular Atrophy (Avexis) 10:30 AM – 12:30 PM SYMPOSIUM: NEUROIMMUNOLOGY: International Consensus Opinions in Opsoclonus-Myoclonus-Ataxia Syndrome 10:30 AM – 12:30 PM SYMPOSIUM: STROKE: Pediatric Stroke: Hot Topics, Global Challenges 1:00 PM - 2:00 PM Industry Sponsored Educational Seminar: Patient Identification, Evaluation, and Management – Addressing Multiple Challenges in Neurodegenerative Lysosomal Storage Diseases (Takeda) 1:00 PM – 3:00 PM SYMPOSIUM: NEURO-ONCOLOGY: Pediatric Mixed Neuronal-Glial Tumors: New Classifications, Molecular Understandings and Targeted Therapy 3:30 PM – 5:30 PM SYMPOSIUM: NEUROMUSCULAR DISEASE: Advances in Pediatric Charcot-Marie-Tooth Disease 3:30 PM – 5:30 PM SYMPOSIUM: NEONATAL SEIZURES: Practical Approaches to Classification, Diagnosis and Management 6:00 PM – 8:00 PM SYMPOSIUM: EPILEPSY: Infantile Spasms – Current Management – A Global Perspective; The Way Forward 6:00 PM – 8:00 PM SYMPOSIUM: NEUROINFECTIOUS DISEASE: Tropical Infections of the CNS: A Worldwide Problem 6:00 PM – 8:00 PM SYMPOSIUM: MOVEMENT DISORDERS: Lessons from Tourette Syndrome – Better Understanding of Development of the Child Brain On Demand (24/7) Posters & Video Posters On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word)

82 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 ALL TIMES PACIFIC DAYLIGHT TIME 15 Minutes Q&A Will be Added to Each CME Session (other than plenary/award lectures – no Q&A)

Wednesday, October 21, 2020 6:00 AM – 6:55 AM SHEILA WALLACE AWARD LECTURE: Suvasini Sharma, MD, DM; Lady Hardinge Medical College and Associated Kalawati Saran Children’s Hospital, New Delhi, India: Dietary Therapies for Epilepsy in Low Resource Settings: Challenges and Successes 7:00 AM – 7:55 AM PHILIP R. DODGE YOUNG INVESTIGATOR AWARD LECTURE: Hsiao-Tuan Chao, MD, PhD; Baylor College of Medicine, Houston, TX, USA: The Impact of Serendipity: From “Rare” Neurodevelopmental Disorders to Common Insights 8:00 AM – 10:00 AM Industry Sponsored CME Seminar: SMA Horizons: What is the Future of SMA Management? (Genentech) 10:30 AM – 12:30 PM SYMPOSIUM: NEUROGENETICS: Current Status of Developmental Encephalopathies: Rett Syndrome, MECP2 Duplication Disorder, CDKL5 Deficiency Disorder, and FOXG1 Disorder 10:30 AM – 12:30 PM SYMPOSIUM: NEUROIMMUNOLOGY: Cutting Edge Technology in Neuroinflammation: Advancing Science and Increasing Capacity in Low and Middle-income Countries 12:30 PM – 2:30 PM Industry Sponsored CME Seminar: Developmental and Epileptic Encephalopathies (Zogenix) 1:00 PM – 3:00 PM SYMPOSIUM: COGNITIVE-BEHAVIORAL NEUROLOGY: The Molecular & Cellular Basis of Developmental Cognitive & Behavioral Disorders 1:00 PM – 3:00 PM SYMPOSIUM: SLEEP: Integrating Pediatric Sleep Medicine into Child Neurology 3:30 PM – 5:30 PM SYMPOSIUM: CEREBRAL PALSY: An Open Discussion on the Definition of Cerebral Palsy 3:30 PM – 5:30 PM SYMPOSIUM: EPILEPSY: Epilepsy and Psychiatric Comorbidities 6:00 PM – 8:00 PM SYMPOSIUM: GLOBAL NEUROLOGY: Global Challenges and Opportunities in Inpatient Child Neurology 6:00 PM – 8:00 PM SYMPOSIUM: EPILEPSY: Ketogenic Diets in Child Neurology – A Tale of 100 Years: What Does the Future Hold? On Demand (24/7) Posters & Video Posters On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word)

SPECIAL INTEREST GROUP MEETINGS

Monday, October 12 Wednesday, October 14 Cerebral Palsy: 2:30 pm - 4:00 pm Early Stage Investigator: 3:00 pm - 4:30 pm Telemedicine: 4:30 pm - 6:00 pm Neurogenetics: 3:00 pm - 4:30 pm Neurodevelopmental Disorders: 4:30 pm - 6:00 pm Thursday, October 15 Tuesday, October 13 Peds Demyelinating Disease: 12:30 pm - 2:00 pm Education: 3:00 pm - 4:30 pm Friday, October 16 Neuro-Oncology: 12:30 pm - 2:00 pm Neonatal Neurology: 12:30 pm - 2:00 pm

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 83 Schedule at a Glance

ALL TIMES PACIFIC DAYLIGHT TIME 15 Minutes Q&A Will be Added to Each CME Session (other than plenary/award lectures – no Q&A)

Thursday, October 22, 2020 6:00 AM – 6:55 AM LINDA DE MEIRLEIR NEUROMETABOLIC AWARD LECTURE: Lance Rodan, MD, FRCP(C); Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA: Update in Pediatric Neurometabolic Disorders 2020 7:00 AM – 7:55 AM HOWER AWARD LECTURE: Kenneth J. Mack, MD, PhD; Mayo Clinic, Rochester, MN, USA: Migraine, Vertigo, and Dizziness 10:00 AM - 11:00 AM Industry Sponsored Product Theater: The Evolving Role of Early Pediatric Care for Spinal Muscular Atrophy (SMA) and a Treatment for Presymptomatic and Early-onset SMA (Biogen) 10:30 AM – 12:30 PM SYMPOSIUM: NEONATAL NEUROLOGY: Neurodevelopmental Outcomes in Congenital Heart Disease: From Fetal Pathogenesis to Prevention 10:30 AM – 12:30 PM SYMPOSIUM: NEURODEVELOPMENTAL DISORDERS: IN SPANISH: Beyond Pharmacological Treatment for Neurodevelopmental Disorders: What Parents and Physicians Want to Know About the Available Options 1:00 PM – 3:00 PM SYMPOSIUM: ETHICS: Humanism in Child Neurology: The Time is Now! SYMPOSIUM: HEADACHE: Migraine Management in 2020: New Options for Treatment and How to Incorporate Recent Guidelines and Novel Treatments in Clinical Practice 3:30 PM – 5:30 PM SYMPOSIUM: NEUROMUSCULAR DISEASE: Gene Transfer for Children: What We Know Now 3:30 PM – 5:30 PM SYMPOSIUM: EPILEPSY: IN SPANISH: Pediatric Epilepsy. When Drugs Don’t Work 6:00 PM – 8:00 PM SYMPOSIUM: NEURO-METABOLIC DISORDERS: Vitamin Responsive Conditions in Child Neurology: Whats New? 6:00 PM – 8:00 PM SYMPOSIUM: GLOBAL NEUROLOGY: Pediatric Neurology. A Global Perspective On Demand (24/7) Posters & Video Posters On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word) Friday, October 23, 2020 6:00 AM – 6:55 AM FRANK FORD AWARD LECTURE: Charles Newton, MD; University of Oxford, Oxford, United Kingdom, KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya: The Global Burden of Paediatric Neurological Disorders 10:30 AM – 12:30 PM SYMPOSIUM: TRAUMATIC BRAIN INJURY: New Advances in Management, Treatment and Rehabilitation 10:30 AM – 12:30 PM SYMPOSIUM: NEUROMETABOLIC DISORDERS: Novel Advanced Treatment in Neurogenetic Disorders 1:00 PM – 3:00 PM SYMPOSIUM: NEUROIMMUNOLOGY: MOG Antibody Associated Neurological Disease – An Update for the Clinician 1:00 PM – 3:00 PM SYMPOSIUM: GLOBAL NEUROLOGY: Integration of Global Health and Child Neurology: Perspectives and Successful Partnerships Around the World On Demand (24/7) Posters & Video Posters On Demand (24/7) Child Neuro Night Club: American Creativity, Ingenuity and Diversity (Jazz & Spoken Word)

84 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 To Access Sessions On Demand thru TOGETHER APART March 2021, • You must be registered by virtual2020 October 23 ICNA • CNS ICNA • CNS

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting OCTOBER 12-23, 2020 16th International Child Neurology Congress Sharing Knowledge • Sowing Friendships • Spreading Hope 49th Annual Child Neurology Society Meeting

Registration CLICK HERE REGISTRATION FEES admit delegate to all Live Open Sessions, Live SIG Meetings, and On-Demand ePoster and Video-Poster TO REGISTER Sessions. Junior Members also admitted to Junior Member Sessions. or go to NDC: Traumatic Brain Injury requires additional course fee. https://www.badgeguys. com/reg/2020/cnsv/ PLUS.... register.aspx REGISTRATION FEE good for all recorded sessions available On-Demand November 2020 - March 2021.

NDC COURSE FEE REGISTRATION CATEGORIES (ADDITIONAL - FEE OPTIONAL

ICNA High Income $500 $60 ICNA Member Upper Middle Income $300 $35 ICNA Member Lower Middle Income $100 $25 ICNA Member Lower Income $75 $25 ICNA Junior Member $50 $25 CNS Active Member (Dues paid by 7/31) $500 $60 CNS Active Member (late or unpaid dues) $600 $60 CNS Emeritus Member $100 $60 CNS Junior Member $50 $25 Medical Student/Resident $50 $25 Non-CNS Member/Non-ICNA Member $750 $60 Non-CNS Member and Non-ICNA Member - $600 $60 ABPN Certified * *ABPN Certified neurologists who are not CNS or ICNA members are eligible to register at CNS Active Member rates thanks to a grant from the American Board of Psychiatry and Neurology (ABPN)

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 85 ICNA • CNS ICNA • CNS Industry-Sponsored Seminars & Product Theaters

16th International Child Neurology Congress Links provided on CNS 2020 Meeting Page: https://www. 49th Annual Child Neurology Society Meeting childneurologysociety.org/meetings/future-cns-annual-meetings

16th International Child Neurology Congress PRODUCT49th Annual Child THEATER: Neurology Society Meeting EDUCATIONAL SEMINAR: Spinal Muscular Atrophy Patient Identification, Evaluation, and Tuesday, October 13, 11:30 AM - 12:30 PM Management – Addressing Multiple Monday, October 19, 5:00 PM - 6:00 PM Challenges in Neurodegenerative Lysosomal Storage Diseases Tuesday, October 13, 1:00 PM - 2:00 PM Tuesday, October 20, 1:00 PM - 2:00 PM

Lysosomal storage diseases (LSDs) are a group of CME SEMINAR: over 70 diseases that are characterized by lysosomal Developmental and Epileptic Encephalopathies dysfunction, most of which are inherited as autosomal (Miller Medical Communicatioins with recessive traits. These disorders are individually funding from Zogenix) rare but collectively affect 1 in 5,000 live births. Thursday, October 15, 12:30 PM - 2:30 PM LSDs typically present in infancy and childhood, Wednesday, October 21, 12:30 PM - 2:30 PM although adult-onset forms also occur. Since LSDs are caused by systematic enzyme deficiencies, they Developmental Epileptic Encephalopathies often present with severe neurological symptoms. encompass an array of devastating conditions Diseases like Gaucher disease, mucopolysaccharidosis marked by treatment-resistant seizures and type II (MPS II), and metachromatic leukodystrophy significant comorbid neurodevelopmental challenges (MLD) present with major neurological symptoms. for which there continues to be a high unmet need. Currently, the mechanisms for these neurological As part of those neurodevelopmental challenges, disease manifestations are not fully understood and many children clinically present with autistic present a diagnostic odyssey and major management tendencies and traits. This symposium will cover the challenges. Although these diseases are distinct with latest understanding of these behavioral challenges; respect to pathology and clinical characteristics, including genetic correlates, clinical characteristics there are important similarities in the unmet needs for and behavior management strategies. these conditions. Some of these include substantial variability in patient phenotypes and associated Educational Objectives: prognoses; the need for biomarkers to support both 1. Discuss the epidemiology, clinical presentation, patient identification and establishment of prognosis; and burden of autistic spectrum disorder (ASD) in improved early diagnosis including newborn screening epileptic encephalopathies (EE); to support earlier intervention; and a requirement for 2. Analyze the key neuroanatomical and molecular treatment approaches that address CNS pathology. determinants that regulate the complexities of Discussion of these unmet needs and a critical review of behavior associate with epilepsy and EE; the manner in which they are now and will be addressed 3. Examine the relationship between seizure is important and timely; and it is the basis for the frequency and executive functions, such as proposed symposium. behavior, emotion, and cognition; 4. Discuss current and emerging behavioral and The product theatre will be presented in the following pharmacologic management approaches for the three sections: treatment of ASD in EE. 1. Neurodegenerative consequences of Gaucher disease across the spectrum of patient phenotypes; (This program is supported by an independent 2. Predicting, assessing, and addressing cognitive educational grant from Zogenix, Inc.) dysfunction in MLD; 3. MPS II: Meeting needs for prognosis and monitoring

86 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 CME SEMINAR: EDUCATIONAL SEMINAR: SMA Horizons: Distinguishing Pediatric Movement Disorders: What is the future of SMA management? Uncovering AADC Deficiency (PTC Therapeautics) (France Foundation with funding from Genentech) Wednesday, October 14, 12:30 PM - 2:00 PM Wednesday, October 14, 4:00 PM - 6:00 PM Monday, October 19, 12:30 PM - 2:00 PM Wednesday, OCtober 21, 8:00 AM - 10:00 AM Pediatric movement disorders can result from a Spinal muscular atrophy (SMA) is the leading variety of pathologies, including errors of metabolism, genetic cause of infant death. There are currently 2 autoimmune processes, neurodegenerative and approved life-saving therapies, with approval of a neurogenetic diseases, and others. Aromatic L-amino third treatment anticipated by summer. Treatment decarboxylase (AADC) deficiency is a rare, inherited early in the disease course is crucial to preventing disorder of neurotransmitter synthesis that presents irreversible neuromuscular damage. However, diagnosis early in life and can have debilitating effects on quality is often missed and/or delayed because of insufficient of life. Due to similarities in clinical presentation with awareness of SMA among clinicians and families, and other conditions (eg, cerebral palsy or epilepsy), because the clinical presentation may appear similar patients with AADC deficiency are often undiagnosed to that of other diseases. The expanding landscape of or misdiagnosed. A differential diagnosis from other SMA treatments necessitates the need for education pediatric movement disorders is therefore critical to that provides real-life, timely solutions based on the identify AADC deficiency and ensure optimal patient most current evidence and expert recommendations. management. Understanding the clinical features, This session will feature world-renowned SMA clinical appropriate patient assessment methods and diagnostic experts Dr. Claudia Chiriboga, Dr. Perry Shieh, and approaches is key in this process. The objectives of Dr. Julie Parsons. They will explain the SMA disease this symposium are to provide an overview of pediatric process, describe mechanisms of action of FDA- movement disorders that may clinically resemble approved and emerging therapies, and highlight the AADC deficiency, provide an overview of key clinical importance and impact of newborn screening efforts features, diagnostic tests, and screening methods for in the United States. Videos of a patient’s journey patients with suspected AADC deficiency, share clinical through recent SMA clinical trials will be interspersed experience with regard to diagnosis of AADC deficiency throughout the session to illustrate real-world in patients who initially presented with symptoms experiences of patients and families, support clinical resembling those of certain pediatric movement relevance of interventions discussed, and engage disorders, review current management options for AADC learners. In addition, patient vignettes will be used to deficiency, and provide a balanced overview of available highlight various approaches to SMA management. information regarding treatments in development. Faculty will describe clinical trial findings and experiences with approved and emerging therapies Faculty will: and discuss how new treatments have impacted clinical 1. provide an overview of pediatric movement disorders care. and highlight AADC deficiency as a movement disorder including etiology, key clinical features, and The session will conclude with an opportunity for diagnostic methods, questions from the audience. At the conclusion of this 2. review case studies and provide an overview of program, the learners will be able to: approaches to distinguishing and identifying AADC 1. Review pathology, genetics, and epidemiology of deficiency in these patients by highlighting key SMA; decision points along the patient journey and the 2. Explain the importance of genetic testing; testing methods that resulted in an accurate diagnosis 3. Discuss newborn screening and its importance in of AADC deficiency, and early diagnosis 3. review current management options for AADC 4. Evaluate new and emerging therapies for SMA. deficiency and provide a balanced overview of treatments in development for AADC deficiency, (This program is supported by an independent highlighting the importance of early and accurate educational grant from Genentech, Inc.) diagnosis in order to provide appropriate disease management. The session will close with a group discussion designed to reinforce the key learning objectives and address questions from the audience.

(This program is supported by an independent educational grant from PTC Therapeutics)

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 87 Links provided on CNS 2020 Meeting Page: https://www.childneurologysociety.org/meetings/future-cns-annual-meetings

CME SEMINAR: PRODUCT THEATER: Progressive Pathways: Advancing Our Understanding of Recent Recommendations and Emerging Gene Therapy in SMA: Therapies for Treatment of Tumors Associated From Clinical Trials to Real-World Experience With Neurofibromatosis Type 1 in Children Thursday, October 15, 10:30 AM - 11:30 AM (PeerView w/ funding from AstraZeneca) Tuesday, October 20, 10:30 AM - 11:30 AM Tuesday, October 20, 8:00 AM - 9:AM

PeerView’s latest MasterClass and Practicum satellite symposium will feature an expert review of: 1. Treatment recommendations, including diagnostic criteria, current management paradigms, and challenges in the care of NF-1 and NF-1–associated tumors in children; PRODUCT THEATER: 2. Insight into the expanding landscape of targeted The Evolving Role of Early Pediatric therapies for NF-1–associated tumors; Care for Spinal Muscular Atrophy (SMA) and 3. Practical guidance on effectively and safely incorporating these strategies and new therapies. a Treatment for Presymptomatic and Early-onset SMA After participating in the activity, learners are Friday, October 16, 10:00 AM - 11:00 AM expected to be better able to: Thursday, October 22, 10:00 AM - 11:00 AM 1. Describe fundamental aspects of NF-1 etiology, pathophysiology, and clinical presentation as they relate to pediatric patients; 2. Summarize current recommendations for NF-1 diagnosis and treatment of NF-1–associated tumors in pediatric patients; 3. Evaluate recent evidence regarding the role of emerging therapies in the treatment of NF-1– associated tumors in pediatric patients, including agents that affect the RAS/MAPK pathway; 4. Assess options for patient-centered treatment of PNs and other NF-1–associated tumors in pediatric patients.

(This program is supported by an independent educational grant from AstraZeneca)

88 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 ICNA • CNS ICNA • CNS Sponsor/Exhibitors

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

Aeglea BioTherapeutics Aeglea BioTherapeutics is a clinical-stage biotechnology company redefining the potential GOLD SPONSOR SILVER SPONSOR of human enzyme therapeutics to benefit people with rare and other high burden diseases. Aeglea’s lead product candidate, pegzilarginase, AveXis, Inc. AstraZeneca (NO BOOTH) is currently being investigated in a pivotal Phase Avexis is dedicated to developing and AstraZeneca is a global, science-led 3 clinical trial for the treatment of Arginase 1 commercializing gene therapies for biopharmaceutical company that Deficiency. patients and families devastated by rare focuses on the discovery, development and life-threatening neurological genetic and commercialization of prescription diseases. Our initial gene therapy for medicines, primarily for the treatment spinal muscular atrophy (SMA) has been of diseases in three therapy areas – Aquestive Therapeutics approved in the United State, Japan and Oncology, Cardiovascular, Renal & Aquestive Therapeutics is a leader in developing The European Union. Metabolism and Respiratory. and delivering medications via our proprietary For more information, please visit PharmFilm® technology. We’ve created www.astrazeneca-us.com and follow a robust, proprietary CNS portfolio. Our us on Twitter @AstraZenecaUS. innovations in oral drug delivery aim to improve the treatment experience for patients with epilepsy and their caregivers.

Association of Child Neurology AveXis Medical Affairs Nurses (ACNN) AveXis is dedicated to developing and The Association of Child Neurology Nurses commercializing gene therapies for patients and SILVER SPONSOR is an international non-profit organization of families devastated by rare and life-threatening nurses and other health care professionals who neurological genetic diseases. Learn more at promote excellence in child neurology nursing www.avexis.com. For medical information, Biocodex practice. The ACNN provides educational please contact us at www.avexismedinfo.com BIOCODEX is a family-owned opportunities at national and regional or 1-833-828-3947. conferences, nursing excellence awards, research multinational pharmaceutical company support, newsletters, and online membership founded in France in 1953, with contacts for networking. Additional information proven expertise in treatments for the and how to join can be found at www.acnn.org. central nervous system. As the maker of DIACOMIT® (stiripentol), we are dedicated to providing education and support to healthcare providers, affected individuals, and their families.

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 89 Exhibitor/Sponsors

GOLD SPONSOR SILVER SPONSOR GOLD SPONSOR

Biogen (NO BOOTH) Cannabinoid Clinical Eisai Inc. At Biogen, our mission is clear: Cannabinoid Clinical is a web-based As the U.S. pharmaceutical subsidiary we are pioneers in neuroscience. platform to provide evidenced- of Tokyo-based Eisai Co., Ltd., we are a Biogen discovers, develops and delivers based cannabinoid information to fully integrated global business with two worldwide innovative therapies for multi-disciplinary audience. Among commercial focus areas: oncology and people living with serious neurological the education resources is Covering neurology (dementia-related diseases and neurodegenerative diseases as well Cannabinoids, a quarterly newsletter and neurodegenerative diseases). as related therapeutic adjacencies. written to provide healthcare providers, To learn more about Eisai Inc., please payers, and policymakers timely visit us at www.eisai.com/US. information on scientific facts, trends,

and regulations to help you make informed decisions. Sign up to receive this newsletter directly by email or read past issues by clicking the link: https:// www.cannabinoidclinical.com/covering- cannabinoids BioMarin Pharmaceutical Inc.

BioMarin is a world leader in developing and European Paediatric Neurology commercializing innovative therapies for rare Society (EPNS) diseases driven by genetic causes. With a 20-year history, BioMarin remains steadfast to A society for physicians with a research or clinical its original mission – to bring new treatments interest in Paediatric Neurology. to market that will make a big impact on small patient populations. Visit www.biomarin.com to learn more.

GOLD SPONSOR SILVER SPONSOR

SILVER SPONSOR Genentech Child Neurology Foundation Genentech is a biotechnology company bluebird bio (NO BOOTH) The Child Neurology Foundation serves dedicated to pursuing groundbreaking science to discover and develop At bluebird, our goal is to recode the as a collaborative center of education medicines for people with serious science, the system – and even the status and support for children living with and life-threatening diseases. Our quo – for life. Powered by multiple labs, neurologic conditions and their families. transformational discoveries include the in-house lentiviral vector manufacturing CNF’s expanding network of patients first targeted antibody for cancer and capabilities and future drug product and caregivers, advocates and partners, the first medicine for primary progressive production, we push ourselves to find researchers and clinicians is here so no multiple sclerosis. answers for the people who need them child will ever have to walk alone. by exploring the cutting-edge spectrum of gene therapy.

recode for life™

90 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 LivaNova As pioneers of the VNS (Vagus Nerve Stimulation) GOLD SPONSOR Therapy® system, we continue to advance SILVER SPONSOR medical device solutions for people affected by treatment-resistant epilepsy. We strive to help Greenwich Biosciences, Inc. where it really counts, where it truly matters Neurelis, Inc. Greenwich Biosciences is focused the most. Sharp, responsive and effective – at Neurelis, Inc. is an innovation-driven on discovering, developing, and LivaNova we serve health and improve lives. neuroscience company focused on the commercializing novel therapeutics from Day by day. Life by life. development and commercialization of its proprietary cannabinoid product product candidates for unmet medical platform. It is our passion and purpose needs in epilepsy and the broader central to continually seek solutions that nervous system (CNS) market. Neurelis transform the lives of those living with Marinus Pharmaceuticals, Inc. has reached a milestone in patient care rare and severe neurological diseases. Marinus Pharmaceuticals is a clinical stage with its first FDA-approved treatment. or additional information, please visit biopharmaceutical company committed to For more information, please visit http:// www.GreenwichBiosciences.com. improving the lives of patients suffering from www.neurelis.com. For more information about our product, rare seizure disorders. Marinus is dedicated to please visit www.GBmedicine.com the development of ganaxolone, offering a new mechanism of action for the potential treatment

of adult and pediatric patient populations with CNS disorders.

National Institute of Neurological Origin Biosciences Disorders and Stroke (NINDS) Origin Biosciences, a subsidiary of BridgeBio The National Institute of Neurological Disorders Pharma, is a biotechnology company focused Invitae and Stroke (NINDS) (www.ninds.nih.gov), part of on developing and commercializing a treatment Invitae’s mission is to bring comprehensive the National Institutes of Health (NIH), provides for Molybdenum Cofactor Deficiency (MoCD) genetic information into mainstream medical information about research funding and free Type A. Together with patients and physicians, practice to improve the quality of healthcare for publications for patients and their families on the company aims to bring a safe, effective billions of people. Our goal is to aggregate most neurological disorders. Home of the free Migraine treatment for MoCD Type A to market as quickly of the world’s genetic tests into a single service Trainer™ app: https://www.ninds.nih.gov/sites/ as possible. with higher quality, faster turnaround time and default/files/ninds_migraine_trainer_flyer_508c. lower prices. Visit www.invitae.com. pdf. Disorder information: https://www.ninds. nih.gov/Disorders. NINDS publications catalog: https://catalog.ninds.nih.gov/. Orphazyme Medical Affairs Orphazyme is pioneering the Heat-Shock Lineagen Protein response to develop innovative therapies for neurodegenerative orphan Since 2010, Lineagen has developed and diseases. Arimoclomol, our lead candidate, is in provided highly optimized genetic testing development for four diseases: Niemann-Pick services for children with autism spectrum disease Type C (NPC), Gaucher Disease, sporadic disorder and other neurodevelopmental Inclusion Body Myositis (sIBM), and Amyotrophic disabilities. Lineagen’s genetic tests, which are all Lateral Sclerosis (ALS). For more information, visit validated and collected by cheek swab, include www.orphazyme.com, LinkedIn or Twitter. FirstStepDxPLUS chromosomal microarray, fragile X syndrome testing, epilepsy panel testing, whole exome and whole genome sequencing, and pharmacogenomic testing.

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 91 Exhibitor/Sponsors

Parent Project Muscular Dystrophy Pediatric Epilepsy Research RosmanSearch Parent Project Muscular Dystrophy fights to Foundation (PERF) RosmanSearch is a Neurosurgery, Neurology end Duchenne. We accelerate research, raise (NO BOOTH) and APP recruitment firm. We place quality our voices to impact policy, demand optimal The Pediatric Epilepsy Research Foundation providers with quality practices nationwide. care for every family, and strive to ensure (PERF) was established in 2004 as a not- We are the only search firm with dedicated access to approved therapies. Our Decode for-profit foundation to support research in teams specializing in neuroscience. Our mission Duchenne program provides free genetic testing pediatric epilepsy and other pediatric neurologic is to be the best, the most expert, and the one (diagnostic and carrier) for families living in the conditions. PERF is proud to support this year’s that is known for quality – every time! US or Canada. 5th Annual CNS John M. “Jack” Pellock Residents Seminar on Epilepsy for PGY5 and PGY6 trainees as part of a 5-year, $50K/year unrestricted Saint Francis Health System educational grant. Warren Clinic, a part of Saint Francis Health System, is looking to add a BC or BE Pediatric Neurologist to our group. This physician will be joining Oklahoma’s largest health system, which was ranked by Forbes as a Best-in-State GOLD SPONSOR Employer in 2019.

PTC Therapeutics PTC is a science-driven, global Sanford Health biopharmaceutical company focused Sanford Health, one of the largest health on the discovery, development systems in the United States, is dedicated to and commercialization of clinically the integrated delivery of health care, genomic differentiated medicines that provide medicine, senior care and services, global clinics, benefits to patients with rare disorders. research and affordable insurance. Headquartered PTC’s ability to globally commercialize in Sioux Falls, South Dakota, the organization products is the foundation that drives includes 44 hospitals, 1,400 physicians and more investment in a robust and diversified than 200 Good Samaritan Society senior care pipeline of transformative medicines and locations in 26 states and 9 countries. Nearly $1 our mission to provide access to best-in- billion in gifts from philanthropist Denny Sanford class treatments for patients who have have transformed how Sanford Health improves an unmet medical need. To learn more the human condition. For information, visit about PTC, please visit us at www.ptcbio. sanfordhealth.org or Sanford Health News. com and follow us on Facebook, on Twitter at @PTCBio, and on LinkedIn.

Sarepta Therapeutics

Our Products & Pipeline: Working urgently to bring therapies to those who need them.

At Sarepta, we are working with urgency to develop breakthrough therapies to treat genetic diseases. Currently, we have more than 40 investigational therapies in various stages of development – many already in late-stage clinical trials. In many cases, development is being accelerated by our gene therapy engine, which potentially provides a more efficient model for drug design.

92 ICNA • CNS | TOGETHER•APART VIRTUAL 2020 St. Luke’s University Health Tourette Association of America UT Health Austin Pediatric Network The Tourette Association of America is dedicated Neurosciences at Dell Children’s St. Luke’s University Health Network (SLUHN) is to making life better for all individuals affected UT Health Austin Pediatric Neurosciences at a fully integrated, regional, non-profit network by Tourette and Tic Disorders. The only Dell Children’s provides world-class medical of more than 16,000 employees providing nationwide organization serving this community, care for children with disorders of the central services at 12 hospitals and 300+ outpatient the Association works to raise awareness, fund nervous system. The center is committed sites. research and provide on-going support through to interdisciplinary care promoting health- To learn more, please visit www.slhn.org its network of 31 Chapters, 83 Support Groups related quality of life through family-centered and 18 Centers of Excellence. treatment, multidisciplinary collaborations, and interinstitutional partnerships. Including clinical academics and research-driven protocols with UT Austin. GOLD SPONSOR GOLD SPONSOR Variantyx Takeda (NO BOOTH) We are a CLIA/CAP accredited genomic For over 200 years, Takeda has remained Upsher-Smith Laboratories, diagnostic lab that specializes in testing for committed to bringing better health and LLC rare inherited and neurological disorders. a brighter future to people around the Upsher-Smith Laboratories, LLC is a All of our tests, ranging from single gene world by focusing on four therapeutic trusted U.S. pharmaceutical company to comprehensive genome-wide tests, are areas: Oncology, Rare Diseases, striving to improve the health and lives performed on a WGS-backbone methodology Neuroscience, and Gastroenterology of patients through an unwavering that uniquely detects all major types of genetic (GI). Our neuroscience therapeutic area commitment to high-quality products variation including small sequence changes, is driven by the immense unmet need and sustainable growth. We seek to structural variants, mitochondrial variants of patients suffering from neurological deliver the best value for our stakeholders and tandem repeat expansions. We provide diseases and current therapies include and do more good for our customers. the flexibility to test only the genes that you Major Depressive Disorder (MDD), For more information, visit www.upsher- want to, with the option to reflex up to a Attention-Deficit Hyperactivity Disorder smith.com. comprehensive genome-wide test as part of the (ADHD), and Binge Eating Disorder same test order.

(B.E.D.). In addition to this, Takeda also has a strong legacy in developing treatments for rare genetic and metabolic diseases, including Lysosomal GOLD SPONSOR Storage Disorders (LSDs) with visceral and neurological manifestations, which have a debilitating impact on patients, Zogenix many of whom are diagnosed in early childhood. Our current portfolio for LSDs Zogenix is a global pharmaceutical in the United States includes therapies company passionate about taking on for Gaucher Disease and MPS II (Hunter the complex challenges of developing Syndrome). For more information on our therapies with the potential to transform pipeline and areas of focus please visit the lives of rare disease patients and their families. https://www.takeda.com/what-we-do/.

ICNA • CNS | TOGETHER•APART VIRTUAL 2020 93 CONNECTING WITH PARTNERS Professors of Child Neurology

What time is it in California? Tim Lotze, M.D. | President, Professors of Child Neurology

ome of you may be familiar with the radical proposal that all time zones should be S abolished and replaced with a so-called “Universal Time.” Steve Hanke, professor of applied economics, and Dick Henry, professor of physics and astronomy at Johns Hopkins are big proponents of this concept. You can learn more about their reasoning related to economic and health benefits as well as some of the international politics of time zones at this link: https://www.wired.co.uk/article/universal-time-zones.

Time zone issues can be especially vexing in this pandemic. Like me, I am sure that many of you have had at least one experience of either confusing others or being confused yourself as to exactly what time zone some Zoom meeting was scheduled for when it involved people from across the country. I thought that I was a total “Time Zone Pro” until the day when I logged in to begin a meeting that I had scheduled with some members of the PCN, only to find that it was just ending. It recently got even worse for me, when I sent an incorrect meeting reminder to Nancy Bass- I got the time right but not the right month. Seems that I am alert but not oriented.

Time zone issues will also be tricky as we come into this virtual interview season and try to figure out how to coordinate applicants from the two coasts with faculty and residents from our programs, not to mention how they might also learn about our related pediatrics and adult neurology programs. One lesson that I learned from the most recent PCN webinar is that the internet has no time zone, and this is where our applicants are going to try and learn all that they can about our programs at whatever time they would like. For applicants, social media is especially important (and more valuable than program swag!) as a method for all of us to continue to advertise and highlight aspects of our programs. A general Tweet or Instagram message from you (or even better, your residents) about what is happening in your program is a cost effective and fair way to connect with the masses. I am sure that this will be an important part of recruitment for years to come.

For the upcoming virtual Professors of Child Neurology meeting at ICNA/CNS, I have triple checked the day and time and set up reminders and alarms on all my gadgets so that I do not miss it! We are all set for October 12, 2020. We will start at 1 PM Pacific Daylight Time with our traditional business meeting followed by a 2-hour CME session beginning at 2:15 PM Pacific Daylight Time.

94 Child Neurology Society | Fall 2020 What time is it in California?

related publication if you have not done so already: “Child neurology in the 21st century: More than the sum of our RVUs” (https://pubmed.ncbi.nlm.nih.gov/31874925/). Due to our time zone issues, all ICNA-CNS talks, to include this session, have been pre-recorded. However, I am hoping that we will be able to engage in a “live” discussion, since I expect the majority of attendees will be coming from North America and (more or less) in the same time zone.

My time as the PCN President comes to an end with the conclusion of this meeting. It has been my privilege to Karen Ballaban-Gil have served in this position for the past couple of years, Rujuta Wilson and the time went by fast… too fast for me to have gotten to all of the things needing to be done, and I wish that I had more of it to accomplish what is still left. However, the PCN will certainly be in excellent hands with its current Our 1-hour business meeting will be via a special link sent Board members to include the incoming President, Nancy out just to PCN members via CNS Connect. The business Bass. I will be stepping into a leadership position with the meeting will include our usual reviews of the Match, American Academy of Pediatrics, Section of Neurology Treasurer report, K12, and a discussion of By-Laws revisions. Executive Committee. I hope to continue to partner with We will also introduce and hear comments from the two the PCN, so that together we might better connect with candidates nominated to run for Director at Large: Karen student and pediatric resident AAP members to let them Ballaban-Gil and Rujuta Wilson. I shoud note that Rujuta know about Child Neurology and NDD earlier in their currently serves on the PCN Board of Directors, having filled training. out the 2nd year of my term when I became President; she is running this year to serve a full term of her own). I look forward to seeing you all online in the coming weeks and in person in the coming year! The subsequent 2-hour CME session will be open to other attendees of the ICNA-CNS meeting. I am looking forward Sincerely, to this session, as we will have Jimmy Reese presenting on Tim Lotze, M.D. the creation of a clinician educator pathway followed by President, Professors of Child Neurology Mary Zupanc discussing the findings and recommendations Professor of Pediatrics and Neurology of the CNS Task Force investigating the practice of Child Texas Children’s Hospital Neurology in the 21st century. Please be sure to read the Baylor College of Medicine

Child Neurology Society | Fall 2020 95 CONNECTING WITH PARTNERS Program Coordinators of Child Neurology

Dear Colleagues Adam Finney, MS | Vice-President, PCCN

e are thrilled to invite all Child Neurology residency program coordinators W to attend the 7th Annual Program Coordinators of Child Neurology (PCCN) Conference. The conference this year will be virtual, but we will still have a great time learning and helping each other. As the conference plans come together, there are a few items worth highlighting.

We formed our coordinator group in 2014 to help fill a gap in the world of GME for Child Neurology residency programs and provide support, knowledge, and skills to the coordinators in their daily managerial role. Even though we continue to see substantial turnover in the coordinator workforce, I believe we have helped flatten the learning curve and have seen some consistency, at least among program coordinators who participate with the group. We could not have done any of this without Terri Feist.

We have a full three-day agenda and will again provide a Coordinator Boot Camp on the first day. The remainder of the conference will include a wide variety of topics, including recruiting, evaluation methods, and technology. Finally, we will have sessions regarding coordinator development and efforts nationally to advance the recognition and role of the Program Coordinator.

We aim to continue to provide support to child neurology residency coordinators by sharing best practices and practical tools for residency management. We are thankful to have the support of the Professors of Child Neurology and the Child Neurology Society, and look forward to working with them as we continue to advocate for improvements in GME and the role of the residency coordinator.

To register (recommend by October 8): Program Coordinators: https://www.badgeguys.com/reg/2020/cnsv/register.aspx?type=PC

2019 Program Coordinators of Child Neurology Conference

96 Child Neurology Society | Fall 2020 CONNECTING WITH PARTNERS Association of Child Neurology Nurses

Dear Colleagues Dear ACNN Colleagues Jennifer Coffman, JD, MSN, CPNP-AC, CNRN | President, ACNN

s autumn represents releasing the old to make way for the new, it is only fitting A that ACNN is embracing a new chapter as we move through this season. We have always maintained a close relationship with the Child Neurology Society (CNS); for the past 7 years ACNN has been actively managed by CNS’s administrative offices. Both ACNN and CNS have realized great growth and success over these years – to the point where CNS no longer has the capacity to provide these services for us.

What does this mean for ACNN? It means releasing the old to make way for the new. It means finding a new association management company to shepherd us into our next chapter. It means change. But this also means opportunity, growth, and the possibility of continued prosperity.

I’ll be the first to admit that this past year has been challenging for ACNN. Between navigating our relationship with CNS and the limited resources available, individually dealing with a global pandemic, quickly pivoting to an all-virtual conference, and searching for our next management partner, the ACNN board members and volunteer committee members have been stretched in ways we never thought possible. Regardless, we stay committed and focused on our members and providing value in membership. Likewise, we ask that you stick with us through this temporary tumult.

As we move into 2021, we will be transforming ourselves – shaping an ACNN that is more responsive to members, has a clear vision and mission, and expanded member offerings. We look forward to continuing our close, collaborative relationship with CNS while simultaneously creating a distinct organization, serving nurses that are in the service to children with neurological disorders. More details will be shared at our all- member annual business meeting during the upcoming conference.

Last, I want to invite everyone to join us for our first-ever virtual Annual ACNN Educational Conference, October 19-21, 2020. It is sure to be filled with timely clinical updates and thought-provoking presentations. Come learn with us. To ensure full access beginning Monday morning, October 19, I urge you to register one week ahead of time (by October 12) by clicking https://www.badgeguys.com/reg/2020/cnsv/registeracnn. aspx. Those registering for the ACNN Conference will also have free access to the CNS- ICNA Joint Meeting (other than NDC Symposium; extra course fee required); a separate URL/log-in is required: To ensure full access beginning Monday morning, October 12, I urge you to register by October 8 if interested in attending CNS-ICNA, and by October 12 if attending only ACNN.

October 19-21, 2020

Child Neurology Society | Fall 2020 97 Association of Child Neurology Nurses Claire Chee Nursing Excellence Award 2020 Jennifer McCrave RN, BSN, CNRN Boston Children’s Hospital, Boston, MA

he Association of Child Neurology Nurses (ACNN) She has been recognized for her expertise with the Tuberous T is pleased to award the 2020 Claire Chee Nursing Sclerosis population and role as clinic coordinator. She was Excellence Award to Jennifer McCrave RN, BSN, CNRN. Jennifer selected as the nurse coordinator’s voice on the TSC Clinic has been a nurse at Boston Children’s Hospital for the past 22 Focus group which is evaluating the TSC Clinic standards years in the neurology clinic. She has served as Clini of care, patient survey metrics, and clinic structure. She has received several awards at Boston Children’s including the Daisy Jennifer graduated from Brockton Hospital School of Nursing. Award in 2010, Excellence in Nursing Leadership Award in She furthered her education receiving an Associate of Science 2013 and the Mark Proctor and Scott Pomeroy Neuroscience Degree from Fisher College and Bachelor of Science degree Nursing Excellence Award in 2017. from Curry College. Organized, kind, efficient, an extraordinary leader and mentor Jenn has worked closely with Dr. Sahin in the multidisciplinary is how Jen is described by her co-workers. “She is such an Tuberous Sclerosis Program. Dr. Sahin stated: “She is a integral part of the care that I provide to my patients that it is passionate advocate for the patients and their families hard to imagine how we would function without her,” stated and has helped to initially develop and now expand our Dr. Sahin. multidisciplinary program.” As a result of her collaborative work a social worker and educational specialist were added to the Dr Basil Darras reported “Jen goes beyond her call of duty, program. Her efforts with this population were recognized by she even works on evenings and weekends, if needed, to close the Tuberous Sclerosis Alliance and she was invited to apply for the loop on certain cases; highly responsible and effective!” a position on the TS Alliance Professional Advisory Board. She A quote from a patient summarizes Jen’s compassion and currently serves on the TS clinic committee. commitment to the care of her patients: “Nurse Jen, or as we call her “Z’s girl”, has been with us since his diagnosis. Jen has Over her many years at Boston Children’s one of her been our guiding light and she’s never faltered. Nurse Jen has supervisors, Deborah Shiers, described Jen as a “compassionate walked us through the most uncharted of territories, and she’s crusader. She strives to bring optimal wellness for both the always done it with care….but most importantly she has done patient and the family, while managing the effects of disease it with encouragement, patience and care….Jen doesn’t stop and navigating the most complex of systems. She has led many there; she makes time to check on me and always finds a way initiatives to improve patient safety and quality of care that to put me at ease when I feel helpless. I don’t think we would have been adopted by many across the organization.” have made it through without nurse Jen, our guiding light.“ Jen McCrave is an exceptional child neurology nurse. She has As the Clinical Coordinator for the Neurology clinic she is dedicated her career to the care of children with neurological responsible for subspecialty program development, overseeing conditions and works to improve their lives. Jen embodies the the day to day operations of the clinic, managing schedules characteristics of the Claire Chee Nursing Excellence Award and and completing performance reviews. She serves as a mentor to is a highly deserving recipient. new staff and has inspired and trained many of the neurology nurses. She has functioned as the research nurse on several clinical trials. She has been involved in several performance improvement projects within the Neurology Department, such as the Magnet Recognition Project. She has been involved with multiple committees and projects at Boston Children’s.

98 Child Neurology Society | Fall 2020 Association of Child Neurology Nurses 2020 Nurse Practitioner Excellence Award Dianne Kulasa-Luke, APRN-CNP, PPNP-BC Akron Children’s Hospital, Akron, OH

ianne Kulasa-Luke, APRN-CNP, PPNP-BC has worked Dianne is supportive of patients and families. Families turn to D since 2006 as a nurse practitioner at Akron Children’s her for questions and concerns. “She has the ability to get to Hospital in Akron Ohio. She is the 2020 Association of Child the heart of an issues and share her solutions and thoughts in a Neurology Nurses Nurse Practitioner Excellence Awardee. She supportive and collegial way,” noted one of her colleagues. was nominated by Dr. Margaret McBride. She is as avid learner. Whether researching information to Dianne has provided leadership, teaching and excellent clinical update a lecture or preparing for journal club she is always care in the field of child neurology for her entire career. Starting looking for new information to enhance her knowledge base. out as a staff nurse caring for patients with neurological/ She shares this information with colleagues. One colleague neurosurgical needs she has continued to care for children with note: “Her documentation is sophisticated. She seeks out neurological issues in various settings. opportunities to advance her own knowledge and expertise in neurology. In a recent care conference, she was the one to She graduated with her Bachelor or Science in Nursing from cite the new ILAE Epilepsy Classification system published last The Ohio State University. She continued her education at Ohio month, having already found and attended a seminar on how State and received her Master of Science in Nursing – Clinical to use it and having already begun to use it in practice.” It Specialist track. She attended University of Akron’s Post maters should be noted here that she regularly attends conferences and courses and completed her Pediatric Nurse Practitioner Program seminars. there. Dianne was nominated for “Best in Nursing” by the American Health Council. In 2017 she was recognized by Akron Children’s Dianne has been a teacher since early in her career. As Hospital for published authors from 2015-2016 and 2018-2019. clinical leader he is responsible for the orientation of the She is involved in several professional organizations including nurse practitioners new to neurology. She continues to act Association of Child Neurology Nurses (ACNN), American as a preceptor for nurse practitioner students. “Dianne has Epilepsy Society, American Academy of Neurology (AAN), Ohio contributed to the understanding and knowledge of nurses Association of Advanced Practice Nurses (OAAPN), Sigma Theta and physicians caring for children with neurologic problems,” Tau and National Association of Pediatric Nurse Practitioners according to Dr. McBride. A new advanced practice provider in (NAPNAP). She has been involved with numerous committees the group was noted as saying, “her advice is always so helpful. with ACNN including planning, education and clinical practice. Her energy and compassion make us want to be like her.” She was the Region 3 Coordinator. She has delivered talks at local, regional, and national meetings. Dianne cares for a complex group of patients and is an integral She is a sought after lecturer on neurological issues and has part of the new seizure and complex seizure clinic. She has presented to students at University of Akron, and Kent State participated in other clinics as needed. She acted as the TBI University in nursing, family studies, and child life programs. nurse practitioner for several months. The coordinator of the Dianne has devoted her entire career to the care and program noted: “Although this area was outside of her usual understanding of children with neurologic disorders. In addition experience, she was able to asses the complex patients and to her numerous professional activities, she volunteers yearly make referrals to psychology or neuropsychology as necessary. with the local Epilepsy Association during Epilepsy Awareness She was able to discern whether there was a psychological Week. Dr. McBride noted: “Dianne’s enjoyment of and overlay in the patients with prolonged post concussive dedication to her work is infectious. It is fun and a privilege symptoms. She addressed the multiple sequelae seen in TBI to be her colleague.” With this high praise, the Association of including mood changes, sleep problems, headaches and Child Neurology Nurses is honored to present the 2020 Nurse academic difficulties. She was able to determine who needed Practitioner Excellence Award to Dianne Kulasa-Luke. close follow up. She was very knowledgeable.”

Child Neurology Society | Fall 2020 99 Association of Child Neurology Nurses Innovative Practice Award Nancy A. Auer, FNP-BC, APRN Nationwide Children’s Hospital, Columbus, OH

he 2020 Association of Child Neurology Nurses In developing the tiered behavioral support, parents, and T Innovative Practice Award recipient is Nancy A. health care workers were interviewed about previous Auer, FNP-BC, APRN. Nancy Auer along with Emily Newton experiences with REE and potential challenges for patients Schreiber, PsyD and Mary Wojnaroski, PhD were instrumental with ASD. Challenges were identified as: ASD symptoms in the development of a Multi-disciplinary Support Program and problem behaviors, specific medical procedures, parent/ for Children with Autism Undergoing a Refractory Epilepsy child expectations and preparation for admission, and Evaluation at Nationwide Children’s Hospital in Columbus, inpatient provider’ training experience and knowledge of OH. patient’s needs prior to admission. Data indicated that the greatest point of intervention may be preparation prior to the This project was a collaborative effort between Neurology, admission to identify and problem solve challenges for each Developmental Psychology and the Autism Center at individual child. Each child was placed into a tier. The tiered Nationwide Children’s Hospital. approach included the following: Tier 1: Studies have shown that 20-33% of individuals with autism Caregiver interview, caregiver preparation discussion, spectrum disorder (ASD) develop epilepsy with approximately team communication 10% becoming refractory (failing two medications). The needs of children with ASD can present unique challenges Tier 2: to procedures during a refractory epilepsy evaluation (REE). In addition to Tier 1 procedure, 2-3 preparation At Nationwide Children’s Hospital from 2016-2018 33% of sessions for REE patients were admitted for REE were diagnosed with ASD, Tier 3: consistent with epidemiological data. In addition to Tier 1, weekly appointments for systematic desensitization The goal was to create a quality support program that prepared children with ASD and their families for refractory Initially, it was difficult to identify patients with Autism epilepsy evaluation (REE) and help providers feel more being sent for REE. A “Hard Stop” question was developed comfortable when referring patients with ASD for REE. in the electronic medical record to identify those children. To our knowledge, we are the only center in the US that The children with autism are then placed in a pool that is have created a program like this and has operationalized it screened by the development psychologist or psychologist at successfully. the autism center and then triaged into a tier. Getting the patient to be compliant with leaving leads on The program was implemented in January of 2020. From their skull or intracranially implanted ones for the necessary January 2020-March 2020 there have been 8 patients time can be a roadblock for some of these children. Not referred to this program; 100 % were able to complete only was cooperation a concern, but the parents of the child their evaluation. In March 2020 the EMU was closed due to were concerned about the care of their child. They were also COVID-19 health concerns and re-opened in May 2020. We concerned about if the procedure would be traumatizing for expect the numbers will increase once the EMU is opened. their child. Providers were concerned that this would not be Providers are feeling more comfortable in referring patients successful and a more non invasive options might be best. with ASD for REE evaluation after implementation of this Because of these concerns, REE was sometimes delayed in program. these children.

100 Child Neurology Society | Fall 2020 Due to this program the children were able to successfully complete their REE. Thus, there was no loss of revenue for the EMU due to cancelled tests. The team is now looking at ways that his program may be having an impact directly on ASD children’s medical care. They are looking at other ways this program could be implemented for children with ASD having long term monitoring. They are also looking at other ways the collaboration of Neurology and Psychology can help patients and families with epilepsy since psychological comorbidities of epilepsy are prevalent.

Supportive letters from Dr. Anup Patel (Neurology) and Dr. Eric Butter (Psychology) were provided with Ms. Auer’s application for the Innovative Practice Award. Dr. Butter noted, “This interdisciplinary team has been able Got a project to facilitate important, high stakes medical evaluation for a population of children who may have not been referred as readily in the past due to barriers presented by their behavioral challenges.” Dr. Patel commented, or colleague “It is innovative ideas like this quality improvement project that will help improve the care patients with epilepsy receive.“ working on a

It is clear from the material submitted by Ms. Auer and the team that this program has led to improvement for project that you’d both the patient/family and the institution, and that she is highly deserving of the 2020 Innovative Practice Award from ACNN. like to see featured?

Send email to: Dan Bonthius ([email protected]) cc Roger Larson ([email protected])

Child Neurology Society | Fall 2020 101 2020 Virtual+Vital ACNN Conference

October 19-21, 2020

ALL SESSIONS ARE LISTED IN PACIFIC DAYLIGHT TIME (PDT)

There may be last minute changes to the schedule due to the pandemic.

MONDAY, OCTOBER 19 1:15 PM - 1:45 PM TUESDAY, OCTOBER 20 Talking to Your Patients and 9:00 AM - 9:15 AM Their Families About 8:30 AM - 9:30 AM Welcome Cannabidiol (CBD) for Genetics 101 Seizures Associated with Melissa Gibbons, MS, CGC 9:15 AM - 10:15 AM Tuberous Sclerosis Complex Children’s Hospital Colorado, Aurora, CO Janet Brucker Keynote Address: Jessica Krefting, RN, BSN Kaitlin Angione, MS, CGC From Case Studies to Quality University of Alabama at Birmingham, Children’s Hospital Colorado, Aurora, CO Outcomes: The Role of the Birmingham, AL DNP within the 21st Century E. Martina Bebin, MD, MPA Mackenzie Blaile, MS, CGC Melissa Reider-Demer, NP University of Alabama at Birmingham, Children’s Hospital Colorado, Aurora, CO Ronald Reagan UCLA Medical Center Birmingham, AL Los Angeles, CA 9:30 AM - 10:00 AM 1:45 PM - 2:15 PM Genetic Evaluation for Children 10:15 AM - 10:45 AM Seizing the Opportunity for with Developmental Delay, Annual Business Meeting Surgical Interventions Intellectual Disability, and Valerie M. Woodard, RN Autism Spectrum Disorder 10:45 AM - 11:45 AM Wake Forest Baptist Health, Carolyn Dickinson, PNP-BC Break Winston-Salem, NC University of Rochester Medical Center Rochester, NY 11:45 AM - 12:15 PM 2:15 PM - 2:30 PM Playing with FIRE(S): What We Break 10:00 AM- 10:15 AM Know and Don’t Know About Break Infection Related Epilepsy 2:30 PM - 3:15 PM Syndrome in Children Poster Review 10:15 AM - 10:45 AM Jennifer Coffman, JD, MSN, APRN, GLUT 1-DS: Recognition of CPNP-AC, CNRN Clinical Symptoms, Diagnosis, Children’s Hospital Colorado, Aurora, CO and Treatment Rebecca Schultz, PhD, APRN, 12:15 PM - 1:15 PM CPNP-PC, FAES Lunch Texas Woman’s University, Houston, TX

10:45 AM- 11:15 AM Awards

1024 Child2020 VirtualNeurology+Vital Society ACCN | Fall Conference 2020 2020 Virtual+Vital ACNN Conference

11:15 AM - 11:45 AM 10:00 AM - 10:15 AM REGISTRATION FEES Innovative Clinical Practice Award Break AND INFORMATION Presentation: Multidisciplinary Support Program for Children with 10:15 AM - 11:15 AM ACNN Meeting Member Autism Undergoing a Refractory Dysautonomia: The Myths $175.00 Epilepsy Evaluation and Pitfalls in Assessing and Nancy A. Auer, APRN Managing this Complex ACNN Meeting Non-Member Nationwide Children’s Hospital, Patient Population $250.00 Columbus, OH Angelina Koehler, CPNP, MA Children’s Hospital Colorado, Aurora, CO Neurobiology of Disease in 11:45 AM - 1:00 PM Children (NDC): TBI Course Fee Lunch 11:15 AM - 11:45 AM $60.00 While We are Sleeping,

1:00 PM - 1:30 PM the Glymphatic System is All ACNN registrants will have An Introduction to Hard at Work: The Brain’s Novel access (on a separate website) Neuroimmunology Waste Removal System Patricia Plumb, RN, MSN Elizabeth K. Rende, DNP, APRN, to Joint ICNA-CNS Meeting University Texas Southwestern, Dallas, TX CPNP- PC, PMHS-BC, FAANP CentraCare Health, St. Cloud, MN

WEDNESDAY, OCTOBER 21 11:45 AM - 1:00 PM Lunch 8:30 AM - 9:30 AM Going Global: What Should we 1:00 PM - 1:30 PM be Doing to Lift the Burden of How to Interpret the Black, Headache in our own Spheres? Gray, White, and Bright: Scott Turner, DNP Neuroimaging Overview for University of Alabama Birmingham Child Neurology Nurses and APPs CLICK HERE Birmingham, AL Kathleen Wetherell Griffin, RN, CPNP TO REGISTER Wake Forest Baptist Health Elizabeth K. Rende DNP, APRN, Winston-Salem, NC Or go to CPNP- PC, PMHS-BC, FAANP https://www.badgeguys.com/ CentraCare Health, St. Cloud, MN 1:30 PM - 2:00 PM Pediatric Stroke Diagnostic reg/2020/cnsv/registeracnn.aspx Samantha Weaver, MSN, PNP-AC Barriers and Emerging Care Children’s of Alabama, Birmingham, AL Michele Grimason Mills, RN, MSN, FNP-BC, PNP-AC 9:30 AM - 10:00 AM Ann and Robert H. Lurie Children’s The New Frontier in Hospital, Chicago, IL Headache Management in CGRP Medications Annmarie Kropp, DNP Children’s Hospital Colorado, Aurora, CO

2020Child Virtual Neurology+Vital ACNNSociety CONFERENCE | Fall 2020 1035 CONNECTING WITH PARTNERS Child Neurology Foundation (CNF)

2020 Pediatric Epilepsy Research Foundation (PERF) Elterman Research Grant Recipient

RESEARCH TITLE: Targeting Aberrant Activity-Dependent Myelination in Absence Epilepsy

I am a practicing pediatric epileptologist and neuroscientist at Stanford University. My basic, translational and clinical research efforts are devoted to better understanding pathogenesis and identifying novel treatment approaches in pediatric epilepsy. My doctoral thesis in the laboratory of Dr. Frank Longo at Stanford elucidated the critical role of p75 neurotrophin receptor (p75NTR) signaling in Alzheimer’s disease neurodegeneration, and demonstrated that small molecule ligands of p75NTR prevented and reversed neurodegeneration in rodent models Juliet Knowles, of Alzheimer’s – precursor findings to an ongoing clinical trial for MD, PhD Alzheimer’s disease. Later, as a medical student in clinical rotations, I Stanford University was particularly drawn to Pediatrics. I found Child Neurology to be a challenging but fulfilling combination of my two professional passions, Pediatrics and Neuroscience. I completed residency in Child Neurology and served as Chief Resident before moving on to a Pediatric Epilepsy fellowship, all at Stanford. As a clinician caring for children with epilepsy, I think about how seizures affect brain development and function, and how we might intervene upon those processes to provide more effective treatments. I am studying these questions in the lab, under the mentorship of Drs. Michelle Monje and John Huguenard. My post- doctoral work in rodent models demonstrated that absence seizures can induce abnormal myelination of the seizure network, which in turn contributes to disease pathogenesis. As an independent investigator, I will continue to study how seizures in various forms of pediatric epilepsy impact brain structure and function, and I will use these discoveries to test novel therapeutic strategies. My ultimate goal is to contribute to a new generation of disease-modifying therapies that improve the lives of pediatric patients with epilepsy.

104 Child Neurology Society | Fall 2020 2020 Pediatric Epilepsy Research Foundation (PERF) Shields Research Grant Recipient

RESEARCH TITLE: Identifying Genetic Risk Factors in Congenital Zika Syndrome

Youssef A. Kousa, MS, D.O., Ph.D., is a physician-scientist specializing in neonatal neurology at Children’s National Hospital in Washington, DC. During pediatric internship, he founded an international, trans- disciplinary research team, the Zika Genetics Consortium, to study the 2015 Zika virus pandemic and model human genetic modifiers in neuroinfectious diseases and neurodevelopmental disorders. Dr. Kousa is the Principal Investigator of the Consortium, which now includes 19 co-investigators representing 13 different institutions. Partnering with Youssef A. Kousa, the National Institutes of Health and Centers for Disease Control and MS, DO, PhD Prevention, the Consortium is bringing together mother-infant dyad Children’s National cohorts with 12,000 participants throughout the Western Hemisphere. Hospital Their goal is disease prevention by integrating and leveraging team science, systems biology, and genomics.

Dr. Kousa completed a combined pediatrics and child neurology residency at Children’s National Hospital and the DO-PhD Physician Scientist Training Program at Michigan State University. Through graduate and post-graduate research training, he has focused on human genetics, genetic engineering, developmental biology, immunology, and virology. His accomplishments include creation of an adenovirus- based malaria vaccine, discovery of a conserved gene regulatory network in craniofacial and neural tube development, 30 peer-reviewed publications, and multiple national and international invited research presentations. His awards and honors span academic, research, service, and leadership roles, including the highest honors possible at Michigan State University for a graduate and medical student. Dr. Kousa directs the Perinatal Neuroinfections Clinic at Children’s National Hospital and is an Instructor in Neurology, Pediatrics, & Genomics, and Precision Medicine at George Washington University School of Medicine, Washington, DC.

Child Neurology Society | Fall 2020 105 CONNECTING WITH PARTNERS Child Neurology Foundation (CNF)

2020 NDD Summer Scholarship Recipient

RESEARCH TITLE: Investigating Cortical/Cerebral Visual Impairment and Visual Processing Deficits in Cerebral Adrenoleukodystrophy

Camille Corre is a rising second year medical student at the University of Rochester School of Medicine and Dentistry. Her motivation for studying childhood-onset neurological disease is inspired by longstanding experience working with young people with disabilities in a rehabilitative setting, academic experiences in clinical research on rare neurological diseases, and a family history of facing a neurodegenerative diagnosis. Camille Corre For six summers throughout high school and college, she worked at the Massachusetts Hospital School (now the Pappas Rehabilitation University of Rochester School Hospital for Children), a long-term residential school and hospital of Medicine setting for children and young adults with disabilities. She completed an undergraduate degree in Biological Chemistry at the University of Chicago. She then spent two years as a clinical research coordinator studying conditions like X-linked adrenoleukodystrophy (ALD) in the Center for Rare Neurological Diseases at Massachusetts General Hospital. In child neurology, she is struck by the overlap between providing rehabilitative/palliative care that maximizes existing quality of life, and the development of neurologic interventions that fundamentally change disease course. This summer, with support from the NDD scholarship, Camille will explore the cortical visual impairment and visual processing deficits seen in early cerebral ALD. As the therapeutic landscape of so many childhood neurological diseases like ALD rapidly changes, Camille looks forward to caring for patients across the phenotypic spectrum and empowering them to embrace their abilities.

106 Child Neurology Society | Fall 2020 CONNECTING WITH YOUR FUTURE Personnel Registry

CNS PERSONNEL REGISTRY We offer: EEO Equal Employment Opportunity • Schedule flexibility and sabbaticals for CALIFORNIA Contact: [email protected] work-life balance • Relocation allowance Website: https://www.sutterhealth.org/ STANFORD MEDICINE • Guaranteed salary for two years with physician-opportunities/dublin/pediatric- SEE AD AT BOTTOM RIGHT. production bonus neurology-2772 ______• Generous benefits package • Shareholder eligibility after two years PEDIATRIC NEUROLOGIST BC/BE – PALO ALTO FOUNDATION • 401K, cash-balance retirement plan, MEDICAL GROUP HSA Palo Alto Foundation Medical Group is seeking a full time BE/BC Pediatric Neurologist. Location: Dublin, CA Highlights: • Physician-led and collegial environment • Three existing Pediatric Neurologists POSITION DESCRIPTION: with a high caliber support staff The Department of Neurology and Neurological Sciences at Stanford University School of Medicine • Malpractice tail coverage is seeking board-eligible or board-certified neurologists to join the Department as a Clinical Assistant Professor, Clinical Associate Professor, or Clinical Professor in the Clinician Educator line. Faculty rank Requirements: will be determined by the qualifications and experience of the successful candidate. • BC/BE in Pediatric Neurology • Experience in electroencephalography The major criterion for appointment, reappointment and promotion for Clinician Educators is interpretation and ability to perform excellence in the overall mix of clinical care and clinical teaching appropriate to the programmatic needs the individual is expected to fulfill. Successful applicants will be encouraged to interact with inpatient consultation services is a plus the wide range of clinical, translational, and basic science programs at Stanford. Palo Alto Foundation Medical Group Responsibilities will include care of general and subspecialty neurology patients, and teaching of We are one of the largest multi-specialty medical students, residents and clinical fellows. For qualified candidates, opportunities are available medical groups in the country, made to participate in research, quality improvement, and development of innovative care programs. up of over 1,600 physicians in 40+ Faculty will work in our hospital and clinics at Stanford Health Care (SHC), Lucile Packard Children’s specialties, in practices throughout the Hospital (LPCH), and/or outreach sites in the San Francisco Bay Area. San Francisco Bay Area Our organization QUALIFICATIONS: is nationally recognized for our excellence Candidates must have an MD or equivalent. Fellowship training in a neurology subspecialty, with multiple awards for quality of care, such as autonomic disorders, general (comprehensive) child neurology, epilepsy, intraoperative innovation and leadership. neurophysiologic monitoring, movement disorders, neonatal neurology, neurobehavior, or neurocritical care, is highly desirable. Necessary qualifications include board certification or eligibility Palo Alto Foundation Medical Group (ABPN), eligibility for a California medical license, and suitable clinical and teaching experience. is affiliated with Palo Alto Medical Foundation, a not-for-profit health care APPLICATION INSTRUCTIONS: organization, providing operational and Review of applications will be conducted on a rolling basis. administrative support, including the Interested candidates should send a copy of their curriculum vitae, and a statement/ letter of intent latest technology, allowing physicians to outlining their specialty interest to the secure web portal listed below for each subspecialty: focus on delivering exceptional patient Child Neurology: http://apply.interfolio.com/78400 care Equal Employment Opportunity Statement Stanford University is an equal opportunity employer and is committed to increasing the diversity of its faculty. It welcomes nominations of and applications from women, members of minority groups, protected veterans and individuals with disabilities, as well as from others who would bring additional dimensions to the university’s research, teaching and clinical missions.

Contact: http://apply.interfolio.com/78400

Child Neurology Society | Fall 2020 107 CALIFORNIA continued forward to your reply and thank you for For consideration or to apply, your review. Please do not delay as we please visit our website at https:// ______anticipate a significant response. scpmgphysiciancareers.com. PEDIATRIC NEUROLOGIST: $315,000 | Please contact: John Flynn at medcareers@ For questions or additional information, LIVE AND WORK IN SANTA BARBARA merritthawkins.com or at (866) 406-0269 please contact Michelle Schnorf at 866- and reference PNE-118866 285-5438 or [email protected]. A stable, independent not-for-profit healthcare organization in Santa ______The Answer to Health Care in America. Barbara is seeking a board-certified PEDIATRIC EPILEPTOLOGIST ______pediatric neurologist to join its team. UCSF FRESNO CHILD NEUROLOGY This is a wonderful opportunity for an At the Southern California Permanente Medical Group (SCPMG), a physician- experienced physician to create a new UCSF Fresno Medical Education Program led partnership organization with a service line and take ownership over the and Central California Faculty Medical patient-centered and evidence-based success of an innovative program. Group (CCFMG) are currently recruiting approach to medicine, we believe in for academic pediatrics faculty in Opportunity Highlights giving every member of our community neurology at the Assistant, Associate • Outpatient and inpatient services with the opportunity to live a happy, healthy or Full Professor rank. The successful a manageable call schedule life. From the physicians we employ to the candidate must have completed a • Four-day clinical workweek with patients we serve our mission is to provide residency, be board-certified in pediatrics moderate hospital census a level of care and support that enables and completed subspecialty training in • Beautiful clinic space with all of the each of us to achieve our best. neurology care. latest technology PEDIATRIC EPILEPTOLOGIST • Opportunity to Build A Practice In A The responsibilities include teaching San Diego, California Thriving Coastal Community residents and students and providing We are currently seeking a BC/BE Pediatric specialty care to pediatrics patients. Nestled between the beautiful Pacific Neurologist who has fellowship training in Interest or experience in patient- Ocean and the breathtaking Santa Epilepsy. centered research is desirable. Academic Ynez Mountains, Santa Barbara is a rank and salary will be consistent with picturesque town for families and SCPMG is an organization with strong the successful candidates professional individuals alike to call home. With values, which provides our physicians background. The UCSF Fresno Medical scenic views all around engaging with the resources and support systems Education Program sees patients in a festivities and activities throughout the to ensure they can focus on practicing Regional Medical Center and has very year, youll enjoy an ideal quality of life medicine, connecting with one another successful faculty practice sites. here. and providing the best possible care to their patients. In Southern California, The program is based in Fresno, Community Highlights you’ll enjoy amazing recreational California, where residents enjoy a high • A close-knit community with incredible activities, spectacular natural sceneries standard of living combined with a low housing options and charming and an exceptional climate. cost of living. The result is a quality of neighborhoods life uniquely Californian, yet surprisingly • Excellent public and private schools SCPMG is proud to offer its physicians: affordable. Limitless recreational • Ideal weather and consistent sunshine • An organization that has served the opportunities and spectacular scenery year -ound, allowing for an abundance communities of Southern California for is all accessible in a community with of outdoor recreation, including more than 65 years abundant affordable housing. While hiking, biking, surfing, sailing, and • A physician-led practice that equally there is much to see and do in Fresno, golfing emphasizes professional autonomy and the city is ideally located for fast, • An array of attractions, including a cross-specialty collaboration convenient getaways to the majestic renowned downtown area, Stearns • Comprehensive administrative support Sierra (just 90 minutes away) as well Wharf, a famous local courthouse, and • An environment that promotes excellent as the scenic Central Coast, just two pristine beaches service to patients and one-half hours away. Fresno is the • Immediate access to a regional airport • A fully implemented electronic medical only major city in the country with with multiple direct flights nationwide record system close proximity to three national parks, • An excellent salary, comprehensive including renowned Yosemite National U.S. News ranks California #7 in Best benefits and partnership eligibility after 3 Park. States For Healthcare years For immediate consideration please Please apply online at: https:// We invite you to make a difference in the inquire with an updated copy of your aprecruit.ucsf.edu/JPF02979 communities we serve. CV so we can discuss the position Visit our websites: www.universitymds. by phone. Also, inform me of your com | www.fresno.ucsf.edu best available times to speak. I look

108 Child Neurology Society | Fall 2020 UC San Francisco seeks candidates competitive compensation and a D.C. location that is part of the Johns whose experience, teaching, research, generous benefits package. Hopkins Medicine system. This is an or community service has prepared employed position with All Children’s Qualified candidates must hold a MD/ them to contribute to our commitment Specialty Physicians, a growing group DO degree and be Board Certified/ to diversity and excellence. practice that includes more than 200 Board Eligible in Pediatric Neurology. physicians. Pediatric neurohospitalists The University of California is an For the Epilepsy Position, board will work a schedule of 7 days on - Equal Opportunity/Affirmative Action certification is required. Candidate must focusing on neurology consultations in Employer. All qualified applicants will be able to obtain medical licensure in the pediatric NICU, PICU, pediatric floor, receive consideration for employment Washington, D.C. and Maryland and and EC. The service week is followed by without regard to race, color, religion, possess demonstrated clinical expertise in 7 days off. The following week entails sex, sexual orientation, gender identity, pediatric neurology and epilepsy. Strong seeing hospital and Emergency Center national origin, disability, age or interpersonal skills and the ability to work (EC) follow-up patients in the continuity protected veteran status.orientation, collaboratively with other professionals to clinic. We seek a well-trained child gender identity, national origin, advance clinical programs is essential. neurologist who is comfortable providing disability, age or protected veteran As the largest healthcare provider in a wide spectrum of pediatric neurology status. Maryland and the Washington, D.C., care including long term EEG with region, MedStar Health’s programs and video. Clinical neurophysiology trained services are recognized regionally and neurologists are encouraged to apply. nationally for excellence in medical care. CNS PERSONNEL REGISTRY As members of the Johns Hopkins With 10 hospitals, the MedStar Health All Children’s Institute for Brain DISTRICT OF COLUMBIA Research Institute, and MedStar Medical Protection Sciences, our pediatric group and urgent care centers, our neurologists also regularly draw PEDIATRIC NEUROLOGIST/ 30,000 associates and 6,000 affiliated upon the expertise of specialists PEDIATRIC EPILEPTOLOGIST physicians proudly care for more than in neurosurgery, neuroradiology, half-million patients each year across the MedStar Georgetown University Hospital neuro-oncology, psychiatry, genetics, region. MedStar Georgetown University (MGUH) seeks a Pediatric Neurologist/ neuropsychology, and neuropathology. hospital is a not-for profit, acute-care Pediatric Epileptologist to join our This multidisciplinary institute unites teaching and research hospital with growing pediatric neurology service clinicians, researchers and educators in 600 beds located in the heart of the based in a multidisciplinary clinical, a comprehensive program to promote Nations capital. Visit us at http://www. academic and research environment. optimal neurodevelopment early in medstargeorgetown.org MGUH is an The individual selected will provide life and provide state-of-the-art care Equal Opportunity Employer. patient care, teaching and consultative for children with injuries or illness that services in both an ambulatory and CVs may be sent to dian.p.saunders@ can affect the brain. Johns Hopkins inpatient setting and join a collaborative gunet.georgetown.edu All Children’s Hospital is designated team of clinicians specializing in a NAEC Level 4 epilepsy center. The epilepsy, stroke, neurogenetics, as well $100 million Research and Education as sleep medicine. Building houses our graduate medical CNS PERSONNEL REGISTRY Our division works closely with MedStar FLORIDA education and simulation programs, as Georgetown’s Neurosciences Center of well as an expanded biorepository. It has Excellence, which is home to MGUHs been designed to promote education PEDIATRIC NEUROHOSPITALIST / Epilepsy Center, the first Level Four and research collaboration with our JOHNS HOPKINS ALL CHILDREN’S Epilepsy Center in Washington, DC. other core institutes: Heart, Maternal, HOSPITAL IN ST. PETERSBURG, Fetal & Neonatal, and Cancer & Blood Current pediatric service lines include FLORIDA general child neurology, epilepsy, Disorders. Members of the faculty pediatric stroke and rehabilitation, Pediatric Neurohospitalist consistently participate in the education neuromuscular and neurodegenerative Johns Hopkins All Children’s Hospital of Neurology and Pediatrics residents disorders, movement disorders, and in St. Petersburg, Florida and our Neuro-Oncology fellowship sleep disorders. Physician will oversee provides faculty with additional Johns Hopkins All Children’s Hospital opportunities for teaching and research. bedside long-term EEG monitoring, (JHACH) in St. Petersburg, Florida routine EEG and Video EEG monitoring. is recruiting an additional pediatric In addition to providing clinical care, If appropriate for level of experience, neurohospitalist for our rapidly expanding participation in research will be strongly intraoperative neurophysiologic Child Neurology Program. Our 259-bed supported and encouraged. Qualified monitoring is also available. teaching hospital has been ranked as a candidates may be eligible for an Position includes faculty appointment at U.S. News & World Report Best Children’s academic appointment at Johns Hopkins Georgetown University commensurate Hospital in 8 pediatric specialties including University School of Medicine (academic with experience, opportunity for Neurology and Neurosurgery (2020- rank is open and commensurate with teaching and research along with 2021). JHACH is the only US hospital experience). outside of the Baltimore/Washington,

Child Neurology Society | Fall 2020 109 FLORIDA continued exist. This is an outstanding opportunity Pensacola is a beautiful and vibrant coastal to be a part of a patient-centered, city in the western Florida panhandle. We offer a competitive salary and collegial group committed to delivering The family-friendly city has a flourishing benefits package including relocation high-quality clinical care. The selected downtown and waterfront, numerous assistance, paid vacation, paid time candidate(s) will enjoy a market-based, outdoor activities and cultural offerings, and expenses for CME, 403(B) self- competitive salary and comprehensive and the #1 beach in Florida according contribution retirement plan, medical benefits package. to USA Today. With a low cost of living and no state income tax, Pensacola has malpractice insurance with tail UF Health represents the shared vision and something to offer everyone. insurance, short and long-term disability commitment to patient care excellence coverage, and life insurance and health of more than 22,000 employees of the The University is an equal opportunity, benefits. University of Florida Health Science affirmative action employer committed The Tampa-St. Petersburg area offers Center and UF Health Shands health care to non-discrimination with respect to year-round sunshine, abundant cultural system. With campuses in Gainesville race, creed, color, religion, age, disability, and recreational activities, national and Jacksonville, UF Health includes six sex, sexual orientation, gender identity sports venues, excellent schools and health colleges, nine research institutes and expression, marital status, national an affordable cost of living. We are and centers, two teaching hospitals, two origin, political opinions or affiliations, centrally located to many of Florida’s specialty hospitals and a host of physician genetic information and veteran status amenities, only minutes from beautiful medical practices and outpatient services in all aspects of employment including gulf beaches, 90 minutes from Orlando throughout north central and northeast recruitment, hiring, promotions, transfers, and four hours from Miami. Florida. Our mission is to promote health discipline, terminations, wage and salary through outstanding and high-quality administration, benefits, and training. To confidentially learn more details, patient care; innovative and rigorous Contact: please contact: education in the health professions and Kevin Bogert Joe Bogan biomedical sciences; and high-impact [email protected] Providence Healthcare Group research across the spectrum of basic, (817) 424-1010 (Direct) translational and clinical investigation. The [email protected] UF Health Regional Physicians Network CNS PERSONNEL REGISTRY ______represents the extension of our spectrum of patient-care services to regional ILLINOIS UF HEALTH REGIONAL PHYSICIAN community under the University of (PEDIATRIC NEUROLOGIST) – Floridas College of Medicine. JOIN A GROWING CHILD NEUROLOGY PENSACOLA, FLORIDA PRACTICE AT A MAGNET-DESIGNATED The Studer Family Childrens Hospital HOSPITAL IN IL At UF Health, together, we strive to celebrated its 50th year in 2019 with the create unstoppable momentum toward opening of a new Childrens Hospital. The Carle Physician Group is seeking the goal of improving individual and Childrens Hospital has a full complement additional BE/BC Pediatric Neurologists to community health through discovery, of pediatric subspecialties and support join our established practice in Urbana, clinical and translational science and programs. Through UF Health and Illinois. technology, exceptional education and Ascension Sacred Heart, we are staying on Practice Opportunity Details Include: patient-centered, innovative, high- the leading edge of children’s healthcare. • Level III Perinatal services and Level quality health care. At the heart of our Our mission is to promote health through III Epilepsy Center accredited by the mission is to provide high-quality clinical outstanding and high-quality patient National Association of Epilepsy Centers care and to promise every patient their care; innovative and rigorous education (NAEC) best experience possible. in the health professions and biomedical • 100% child neurology practice UF Health Regional Physicians with The sciences; and high-impact research across • Call consists of only Pediatric Neurology Studer Family Children’s Hospital at the spectrum of basic, translational and patients Ascension Sacred Heart in Pensacola, clinical investigation. The UF Health • Established sleep program Florida seeks a second Pediatric Regional Physicians Network represents the • Onsite MRI and CAT scanning Neurologist. The practice will provide extension of our spectrum of patient-care equipment inpatient consultation services, reading services to regional communities under the • Referral base from more than 20 general of inpatient and outpatient EEGs and University of Florida’s College of Medicine. Pediatricians outpatient follow-up clinic. In addition to • Pediatric subspecialists include clinical care, opportunities for Pediatric Critical Care, Surgery, Cardiology, Resident education and research projects Neurosurgery, Pulmonology, Gastroenterology, Genetics, Urology, Pediatric Psychologists, and Developmental-Behavioral

110 Child Neurology Society | Fall 2020 ______• Excellent benefit package: health/ CNS PERSONNEL REGISTRY dental/life insurance, 403-B plan with INDIANA PEDIATRIC NEUROLOGIST employer match, LTD, relocation Peyton Manning Childrens Hospital at allowance, CME allowance, and paid PEDIATRIC NEUROLOGIST Ascension St. Vincent is seeking a Pediatric malpractice insurance with 100% tail Neurologist for our hospital in Indianapolis. insurance covered Peyton Manning Childrens Hospital at Our ideal candidate will be comfortable • 24 hour in-house coverage provided Ascension St. Vincent (Indianapolis) with child neurology including epilepsy and by Anesthesia, Intensivists, Trauma, Pediatric Neurologist inpatient and outpatient care. and ED; Pediatric Hospitalist & PICU Peyton Manning Childrens Hospital Practice Highlights: are available 24/7 at Ascension St. Vincent is seeking a • Dedicated Neonatal and Obstetric air Pediatric Neurologist for our hospital in • Schedule: M-F 8am-5pm and ground and Pediatric transport Indianapolis. Our ideal candidate will • Call Schedule: 1 in 4 weeks, once every services be comfortable with child neurology 4th night, 1:4 weekends • Two Neurosurgeons (one is a including epilepsy and inpatient and • Home to 300 Pediatric Specialists BC Pediatric Neurosurgeon), outpatient care. • Largest level IV NICU and Pediatric ER in a Neuro-ophthalmologist, six the state Practice Highlights: adult Neurologists, and two • Opportunity to expand program and • Schedule: Monday-Friday 8am-5pm Neuropsychologists on staff nationwide system referral base • Call Schedule: 1 in 4 weeks, once every • 24-hour telephone nurse advisory • Full support of the worlds largest 4th night, 1:4 weekends system in place to help ease demands catholic healthcare system • Home to 300 Pediatric Specialists of call • The most specialized care in the state in • Largest level IV NICU and Pediatric ER in • Flexible scheduling one of the countrys largest cities the state • Experienced support staff • Physician-led organization • Opportunity to expand program and • Teaching and research opportunities • Largest nonprofit health system in the nationwide system referral base are available with the University of country Illinois College of Medicine and the • Full support of the world’s largest Carle Illinois College of Medicine catholic healthcare system Ascension St. Vincent offers a very • Carle Illinois College of Medicine is the • The most specialized care in the state in competitive compensation package nation’s first medical school focused one of the country’s largest cities that includes: Competitive base salaries, at the intersection of healthcare and • Physician-led organization Relocation allowance, CME, Comprehensive engineering • Largest nonprofit health system in the health benefits, Retirement savings plan country (403b) with match, Malpractice with tail About Carle: coverage and generous paid time off. Based in Urbana, IL, The Carle Ascension St. Vincent offers a very Foundation is a vertically integrated competitive compensation package Peyton Manning Childrens Hospital at system with more than 9,500 that includes: Competitive base Ascension St. Vincent is part of Indianas employees in its five hospitals, multi- salaries, Relocation allowance, CME, largest not-for-profit health system with specialty physician groups, health plan Comprehensive health benefits, 22 ministries and over 3000 physicians. and associated healthcare businesses Retirement savings plan (403b) with Features include: a free-standing tertiary including the Carle Illinois College of match, Malpractice with tail coverage and care, pediatric hospital with 40 private Medicine, the world’s first engineering- generous paid time off. inpatient beds and 6 short stay beds, staffed in-house 24/7 by our Pediatric based medical school. Carle is proud Peyton Manning Childrens Hospital at Hospitalist group; a 23-bed PICU staffed to be named a Great Place to Work. Ascension St. Vincent is part of Indiana’s 24/7 by Pediatric Intensivists; a 17-bed Carle Foundation Hospital and Carle largest not-for-profit health system with Pediatric Emergency department staffed BroMenn Medical Center hold Magnet 22 ministries and over 3000 physicians. 24/7 by Pediatric Emergency physicians; designation, the nation’s highest honor Features include: a free-standing tertiary and Indianas largest Level IV NICU with 96 for nursing care and Carle Foundation care, pediatric hospital with 40 private beds staffed 24/7 by Neonatologists. Hospital (CFH) ranks as one of Americas inpatient beds and 6 short stay beds, 50 Best Hospitals by Healthgrades. staffed in-house 24/7 by our Pediatric Interested? Contact: Hospitalist group; a 23-bed PICU staffed Contact Seth Turner, Physician Recruiter Reyna Lute 24/7 by Pediatric Intensivists; a 17-bed (317) 338-6064 or [email protected] Pediatric Emergency department staffed [email protected] 24/7 by Pediatric Emergency physicians; and Indiana’s largest Level IV NICU with 96 beds staffed 24/7 by Neonatologists. Interested? Contact Seth Turner, Physician Recruiter (317) 338 6064 or Seth.turner@ ascension.org

Child Neurology Society | Fall 2020 111 CNS PERSONNEL REGISTRY For more information, please contact: Training includes an MASSACHUSETTS Ariana Caradiaz, Physician Recruiter electroencephalograph (EEG) findings Conference, 2-weeks intensive EEG course, Telephone: 413-794-8701 Fax: 413- Seizure Semiology Conference, Epilepsy INPATIENT/OUTPATIENT 794-5059 Email: Ariana.Caradiaz@ MCQs discussion, Epilepsy Book club, PSYCHIATRY baystatehealth.org Journal Club, and Epilepsy lecture series. Baystate Health (BH), home of the Baystate Health is an Equal Opportunity Inquiries regarding the program can University of Massachusetts Medical employer. All qualified applicants will be directed to Rachel Laws at rmlaws@ School-Baystate, has an outstanding receive consideration for employment cmh.edu Psychiatry opportunity available to fit without regard to race, color, religion, your schedule. Whether you want to sex, sexual orientation, gender identity, ______work part-time, full-time, or per diem. marital status, national origin, ancestry, EXECUTIVE DIRECTOR OF THE BH wants to work with you to find the age, genetic information, disability or THOMPSON CENTER FOR AUTISM AND right fit and schedule that works for protected veteran status. NEURODEVELOPMENTAL DISORDERS your life! & THOMPSON ENDOWED CHAIR IN Opportunities are available for CHILD HEALTH physicians in a variety of practice CNS PERSONNEL REGISTRY The University of Missouri-Columbia, settings ranging from our: MISSOURI the flagship, land-grant, comprehensive • Large academic medical center research university of the University including our well-established PEDIATRIC EPILEPSY FELLOWSHIP of Missouri System started a national Psychiatry Residency Program search for the for the Executive Director • Award winning community hospitals The Epilepsy Fellowship at Children’s of the Thompson Center for Autism and growing group practices in urban, Mercy Kansas City (CMKC) is an and Neurodevelopmental Disorders and suburban, and rural areas ACGME-accredited one-year exclusive seeks nominations and applications. The • Inpatient and outpatient adult or child pediatric epilepsy program that focuses successful candidate will also hold the psychiatry opportunities, working on developing the skills of interpreting Thompson Endowed Chair in Child Health with high performing multidisciplinary electroencephalogram (EEG), and and will provide visionary leadership to teams evaluation/treatment of epilepsy across the Centers interdisciplinary programs • Locations include Ware, Springfield, the pediatric spectrum including and oversee faculty, staff, and programs. Westfield and Greenfield, MA children requiring epilepsy surgery, VNS Reporting to the Executive Vice Chancellor implantation, and ketogenic diet therapy. At Baystate Health, we value the of Health Affairs the Executive Director will CMKC features a Level 4 comprehensive skill and commitment you make to build on the existing world-class programs epilepsy center for the management your patients. Our well-resourced and expand upon continued growth and of intractable epilepsy and surgical staff is comprised of Psychiatrists, broad impact for families, professionals, evaluation. Psychiatric nurses, Psychologists, and trainees. Psychiatric Social Workers and Masters The Epilepsy Section at the Children’s Inaugurated in 2005 with a generous gift prepared specialists, Occupational Mercy is a multi-disciplinary team led by from William and Nancy Thompson / The and Recreational therapists and unit eight Board certified/eligible pediatric Thompson Foundation the Thompson counselors. epileptologists, five adult epileptologists, Center is a nationally recognized clinical, three pediatric neurosurgery faculty, and Baystate Health offers a very training, and research center founded to two pediatric epilepsy neuropsychologists. competitive compensation package improve the lives of individuals and families CMKC serves >5000 clinic patients in that includes generous salary, paid affected by autism spectrum disorder and the epilepsy clinic a year and has an time off, full medical benefits and CME neurodevelopmental disorders through eight-room Epilepsy Monitoring Unit reimbursement and time allowance. world class programs that integrate with over 700 studies and 3000 routine research, clinical service delivery, education Candidates must be BC/BE by the EEGs annually. More than 250 children and public policy. American Board of Psychiatry. Role participate in a Ketogenic diet, and modeling of exceptional clinical, neuromodulation programs with over 60 The Thompson Center is a cohesive, teaching and communication skills in implantations yearly. Our large epilepsy multi-disciplinary home to over a 100 a collaborative and multidisciplinary surgery program includes a LASER faculty, staff, and students from diverse environment is expected. ablation program with a wide variety of backgrounds. Thompson Center research over 30 cases per year. We are one of the is supported by a well-established research Baystate Health was named one of few pediatric centers with Intraoperative core and database and supports a variety Americas Best employers by State in monitoring program with over 25 of federal and industry sponsored trials. 2019 by Forbes. Ranked 14th out of monitored cases per month. The Center is also part of several multi- 74 top employers in Massachusetts, site projects and data collection initiatives. Baystate Health is one of New England’s leading healthcare systems and the largest employer in the region.

112 Child Neurology Society | Fall 2020 Research program growth is a major, CNS PERSONNEL REGISTRY About MEDNAX strategic initiative of the Center and the NEVADA With a 40-year record of success, University of Missouri overall, with a new MEDNAX has grown from a single emphasis on precision health. PEDIATRIC NEUROLOGIST medical practice to a trusted health solutions partner. As part of our national The Center provides care for Exciting opportunity to join and help medical group, we give you the tools you approximately 4,000 patients each year grow the only pediatric neurology need to build the career you want, and across 15,000 visits. Families from across practice in town! the flexibility to adapt as your personal the state of Missouri and beyond are needs and professional interests change. served by 14 clinical sub-specialties. In Due to expansion, we are seeking an addition to clinical breadth, the Center additional BC/BE pediatric neurologist to We invite you to grow with us and help provides training for students in applied join a successful, well-established group shape the future of health care. behavior analysis, medical, psychology, providing pediatric neurology services to MEDNAX is an Equal Opportunity and therapy programs. Las Vegas and surrounding communities Employer for nearly 25 years. In addition to serving We are welcoming applications from patients through local offices, the practice All qualified applicants will receive individuals with an exceptional academic provides pediatric neurology services consideration for employment without record and a strong background to three regional hospitals including regard to race, color, religion, sex, sexual in externally funded clinical and Sunrise Children’s Hospital, Mountain orientation, gender identity, national translational research paired with the View Hospital and University Medical origin, disability or veteran status expertise to grow and develop programs Center of Southern Nevada. The practice and strategize innovative solutions. We Apply Here: http://www.Click2apply. is supported by EEG techs and medical are seeking an active collaborator with net/79d2ykhr4kh9c7w4 assistants. commensurate administrative experience PI121440887 to successfully lead trans-disciplinary and The suburbs of Las Vegas are very family trans-institutional projects and programs friendly. Housing is reasonable, there is no and nourish a collegial and inclusive state income tax, property taxes are very environment. low and outdoor activities are endless and CNS PERSONNEL REGISTRY incredible. The weather is fantastic and For more information on the position NEW JERSEY there are actually some great restaurants. please refer to: If you are into hockey, football and https://www.umsystem.edu/ums/hr/tmr/ PEDIATRIC NEUROLOGIST, BC/BE – baseball, we have you covered with executive-director-thompson-center FULL TIME, CAPITAL HEALTH professional sports teams. For water Considerations: activities, check out Lake Mead. Position Highlights: The University of Missouri is fully • Immediate volume available Benefits committed to achieving the goal of • 100% pediatric neurology opportunity Our clinicians enjoy a competitive a diverse and inclusive community of • Patient-centered environment supported compensation package with many faculty, staff, and students. We seek by cutting-edge technology locations offering sign on bonuses, individuals who are committed to this • Dedicated pediatric ED with long-term relocation and tuition reimbursement. goal of collaboration and inclusion and monitoring capabilities value the many unique qualities and Our benefits include: • Teaching and research opportunities experiences a diverse environment offers. • Health (various options), life, vision, available dental and disability insurance • Achieve work/life balance with minimal Contact: • 401(k) with annual matching program on-call responsibilities Partnering in the search is Anna • Advanced and continuing medical Wiedermann, Senior HR Consultant Our Physicians Enjoy: education for the University of Missouri • Competitive salary and full benefits • Leadership training and advancement System. Inquiries can be sent to package opportunities [email protected] • Six weeks of paid time off • Employee stock purchase plan at a 15% • One week of CME discount • Occurrence malpractice insurance • Professional liability insurance • Employer-paid licensure fees • Support and payment for mandatory license/s and hospital credentialing The Capital Institute for Neurosciences is a center for advanced neuroscience These benefits are for full time employees, care in central NJ serving New Jersey, employees in other types of employment Pennsylvania and the Delaware Valley. The classifications may be eligible for some of Institute includes a dedicated neuro ICU, these benefits. state-of-the-art neuroendovascular suite, neuro OR, stroke unit and the first Mobile Stroke Unit in the region.

Child Neurology Society | Fall 2020 113 • 45 Bed Inpatient Unit • Ability to work collaboratively in an continued NEW JERSEY • 10 Bed Pediatric Intensive Care Unit interdisciplinary setting preferred • 35 Bed Level III Neonatal Intensive Care • Experience teaching house staff and The Institute is part of Capital Health, Unit medical students desired a two-hospital system that includes a • Pediatric Sedation Service hospital in Pennington, NJ and a high- A beautiful and vibrant city, Albuquerque • 24/7 Pediatric Emergency Department acuity hospital in Trenton, NJ that is filled with a diverse culture and • Level II Pediatric Trauma Department includes the system’s Joint Commission distinctive traditions. With consistent • Certified Child Life Specialists Comprehensive Stroke Center and sunshine throughout the year, • HOPE Tower new state-of-the-art Trauma Center. Employed physicians are accompanied by painted skies and pediatric outpatient offices part of Capital Health Medical Group, gorgeous mountain views serving as your • Additional Pediatric Subspecialty Services which is a large, multispecialty group of everyday backdrop, youll find yourself pediatric neurosurgery, behavior/ over 450 providers. basking in an incomparable quality of life. development, hematology/oncology, About Capital Health: pulmonology, endocrinology, infectious COMMUNITY HIGHLIGHTS Capital Health is the region’s leader in diseases, nephrology, rheumatology and • A cost of living lower than the national providing progressive, quality patient genetics average care with significant investments in • Pediatric Residency Program • Some of the top public and private our exceptional physicians, nurses and • Pediatric Neurology Residency Program schools in the state staff, as well as advanced technology. • Academic Appointment to the • Endless opportunities for outdoor Comprising two hospitals (our Regional Hackensack Meridian School of Medicine activities, including skiing, hot air Medical Center in Trenton and Capital ballooning, golfing, hiking, rock Submit your CV for immediate Health Medical Center Hopewell), our climbing, and biking consideration to: carol.petite@ Hamilton outpatient facility and various • An incredible arts scene as well as an hackensackmeridian.org or call primary and specialty care practices array of local shopping and dining 732-673-5000 across the region, Capital Health is a options dynamic healthcare resource accredited by The Joint Commission. For immediate consideration please inquire with an updated copy of your CV To learn more about us and submit CV, CNS PERSONNEL REGISTRY so we can discuss the position by phone. please visit http://www.capital.attnhr. NEW MEXICO Also, inform me of your best available com/jobs/197367/ times to speak. I look forward to your EOE CHIEF OF THE DIVISION OF CHILD reply and thank you for your review. NEUROLOGY: SEEKING A VISIONARY Please do not delay as we anticipate a ______LEADER FOR AN ACADEMIC significant response. CHILD NEUROLOGY OPPORTUNITY OPPORTUNITY IN ALBUQUERQUE, NEW MEXICO Please contact Jay Torio at medcareers@ K. Hovnanian Childrens Hospital merritthawkins.com or at 866-406-0269 The University of New Mexico School Jersey Shore University Medical Center and reference PNE-122402 of Medicine and the Department of Hackensack Meridian Health is seeking Neurology is seeking a board-certified or a BE/BC, fellowship trained Child board-eligible child neurologist to serve Neurologist at Jersey Shore University as the division chief of child neurology. CNS PERSONNEL REGISTRY Medical Center/K. Hovnanian Children’s This position includes research and NEW YORK Hospital located in Neptune, New collaboration opportunities, both in basic Jersey. This is a great opportunity to science and clinical research COLUMBIA UNIVERSITY CHILD live in a desirable coastal location with The successful candidate will be trained in NEUROLOGY RESIDENCY PROGRAM excellent schools and easy access to child neurology and have a strong track New York and Philadelphia. The Division of Child Neurology (led record of administrative accomplishments by Dr. Cigdem Akman) at Columbia The successful candidate will have a and program-building experience. University Irving Medical Center commitment to outstanding pediatric IDEAL CANDIDATE (CUIMC) has an unexpected opening care. They will join an established team • Excellent clinical skills required the in the upcoming PGY3 Child Neurology and enjoy a busy clinical practice along incoming director will be expected to residency program. We are inviting with teaching, research, administrative participate in clinical activities within the applications for the position. Child and supervisory opportunities. UNM Hospital Child Neurology Program Neurology at CUMC is a division of Position Details • Great communication skills desired the nationally #2 ranked Neurology • Employed position with competitive Department at CUIMC and cares for compensation and robust flexible patients in the top ranked childrens benefits package hospital in New York City.

114 Child Neurology Society | Fall 2020 ______The Child Neurology Residency program at CUIMC is one of the PEDIATRIC NEUROLOGIST CHILD NEUROLOGY OPPORTUNITY oldest and most established training Mount Sinai Health System The Department of Neurology at programs in the country. The division Seeking Pediatric Neurologists Albany Medical College seeks BC/BE is a well-recognized center for epilepsy (Academic) Neurologists to expand the Division of and epilepsy surgery, tuberous Pediatric Neurology. Applicants with an sclerosis, neuromuscular disorders, The Mount Sinai Health System interest in general child neurology as neuroimmunology, autism and has openings for full-time pediatric well as those with fellowship training in headache disorders in children, as well neurologists to join our nationally epilepsy to expand the services offered as many other subspecialties of child ranked Division of Pediatric Neurology. by our comprehensive epilepsy center are neurology. The training program will Applicants are sought at any rank both welcome. Albany Medical Center, include a robust exposure to basic, (Assistant, Associate, Professor) with the only academic medical center in translational and clinical research in an academic appointment at the Icahn northeastern New York, is a private, addition to a comprehensive clinical School of Medicine at Mount Sinai that non-profit organization serving over experience in both outpatient based is commensurate with experience and 3 million people. The Department of and hospital based child neurology. resume. The chosen candidate must have Neurology has established programs in excellent clinical skills and an interest Applicants will have to have completed epilepsy, dementia, movement disorders, in outpatient and inpatient pediatric at least two years of a pediatrics neuromuscular disease, pediatric neurology. residency and will spend 36 months neurology, pain management and stroke/ training in child neurology. 12 of these Job Description neurocritical care. Successful applicants months are spent rotating in adult Mount Sinai’s outstanding team of 10 will have a commitment to patient care neurology. Full licensure to practice pediatric neurologists have specialized and supervision of medical students medicine in the United States is interests in epilepsy, movement disorders, and residents, and a desire to work in a required. stroke, neurobehavioral disorders, multiple collaborative environment with neurology sclerosis and autoimmune encephalitis, and pediatric colleagues. Interested applicants should send the as well as general pediatric neurology required documents to Ericka Ayala, Albany Medical College is part of Albany throughout the Mount Sinai Health Graduate Medical Education Specialist Medical Center, northeastern New York’s System in Manhattan. only academic health sciences center, Email: [email protected] Pediatric neurology faculty teach adult which includes Albany Medical Center 1. CV neurology residents, pediatric residents, Hospital, one of upstate New York’s 2. Personal Statement and medical students at the Icahn School largest teaching hospitals. Located at 3. USMLE Scores of Medicine at Mount Sinai during their the heart of New York’s Capital Region, 4. Medical School Transcript clinical rotations in pediatric neurology. Albany is a culturally and environmentally 5. 3 Letter of recommendation In addition, the Division is preparing an diverse area. The Capital Region offers Robert Fryer MD PHD application to ACGME for a pediatric great opportunities for professionals and Program Director neurology fellowship training program. families. Division of Child Neurology Mount Sinai Kravis Childrens Hospital is a Please send inquiries and a C.V. to: Columbia University Irving Medical comprehensive tertiary children’s hospital. Valerie DAloia Center U.S. News and World Report consistently Physician Recruitment Coordinator New York City, NY 10032 selects Mount Sinai Kravis Childrens Albany Med Faculty Physicians Email: [email protected] Hospital as one of the best children’s (518) 262-1333 Phone: 212-342-2919 hospitals in the nation. In the 2018-2019 Fax: (518) 262-6996 annual edition of Best Childrens Hospital [email protected] report, Kravis ranked in five pediatric To learn more about the capital region specialties. It includes a pediatric epilepsy please visit www.amc.edu/greatplace monitoring unit and an active pediatric epilepsy surgical program. Albany Medical College is a private institution and a non-discriminatory We offer a competitive salary and benefits AA/EOE (minorities and women are package. encouraged to apply). Please send your CV, a brief statement of interest, and the names of three referrals to: Alex Cano, DASPR Executive Director, Physician Recruitment Mount Sinai Health System [email protected]

Child Neurology Society | Fall 2020 115 CNS PERSONNEL REGISTRY to the Blue Ridge Mountains and the unwarranted clinical variation, financial NORTH CAROLINA beaches NC, SC, and VA. Please visit planning, oversight of day to day https://www.visitgreensboronc.com/ clinic operations, and driving strategic change. Lead clinicians will also serve as CONE HEALTH IS SEEKING For more information contact and/or the connection point for bidirectional A BC/BE CHILD NEUROLOGIST email your CV to: communication between clinic providers Rebekah Driggers, MBA CHMG Pediatric Specialists is seeking and medical group leadership. In Director, Cone Health Physician & a BC/BE Child Neurologist to expand partnership with clinic administrators, lead Provider Recruitment current child neurology coverage in clinicians are responsible for: (336) 663-5054 Greensboro, NC. The group offers [email protected] • Helping develop a common vision and primarily outpatient child neurology purpose for the clinic that supports services with occasional inpatient ______community needs and Novant Healths consults and a reasonable call schedule. PEDIATRIC NEUROLOGIST mission, vision and values Reading EEGs is essential with an onsite • Partnering with medical group EEG lab in the office. Novant Health Pediatric Neurology is leadership to develop positive office seeking a caring and compassionate CHMG Pediatric Specialists offer culture General Pediatric Neurologist to join our Dietitian, Integrated Behavioral Health • Understanding and communicating rapidly growing pediatric specialty team. Clinician, along with incorporating concepts necessary for the operational This position is located in Charlotte, NC pediatric residents in the clinic. success of the clinic including quality with satellite locations in the south and Direct participation with Neonatal care, safety, accessibility, financial north market of Mecklenburg County. Developmental Follow up clinic and/ responsibility and customer service or Pediatric Complex Care is an option This full-time position will involve seeing • Serving as an effective role model and if interested. There is flexibility to general neurology as well as epilepsy transformational leader pursue additional interests related to patients as part of a pediatric neurology • Providing leadership in teamwork subspecialty training. practice. This physician will act as lead development and provider wellness for the outpatient and inpatient pediatric Minimum qualifications include: Board • Overseeing efficient operation of patient neurologists working closely with the Certification or Board Certification care in the office clinic administrator to achieve system within 5 years of completing training) • Sharing accountability with the clinic goals. in Pediatrics and Neurology, obtaining administrator to achieve the financial full medical license with North Carolina Novant Health Pediatric Neurology is and budgetary goals of the clinic Board of Medicine, full DEA registration, primarily outpatient with hospitalist duties • Counseling individual providers on issues and active privileges with Cone Health. for Novant Health Hemby Childrens such as In Basket management, coding, Preferred skillset/experience: Baclofen Hospital and is part of large pediatric clinical quality, behavior, attendance and and VNS therapies. multispecialty system with an excellent patient complaints built in referral base. Cone Health achieves some of the Contact: http://careerswith.com/ highest quality outcomes in the The practice has several locations in the NovantNeurologist U.S. supported by our Physician south and north market of Mecklenburg Engagement. Cone Health is a large County, centrally located in Charlotte, NC. not-for-profit 6-hospital system with CNS PERSONNEL REGISTRY 1200+ beds, 3 outpatient surgery The physician will help to rotate OHIO centers, and a primary and specialty coverage for the pediatric inpatient floor, care physician network. As a teaching PICU, NICU, and pediatric emergency facility for Pediatric Medicine, Family PEDIATRIC STROKE FELLOWSHIP department for one-week rotations with 4 Medicine, and Internal Medicine. as well other neurologists Nationwide Childrens Hospital as participation in numerous research Department of Neurology and The Ohio trials, Cone Health offers patients access Along with the NH Adult Neurology State University College of Medicine are to the latest developments in medical and Sleep service line, NH Pediatric pleased to announce a Pediatric Stroke care and is a recognized leader in Neurology is associated with an NAEC Fellowship. cardiology, neuroscience, oncology, level IV epilepsy center offering adult and trauma, and rehabilitation. Please visit pediatric epilepsy monitoring. This one-year program will allow trainees www.conehealth.com. to gain extensive knowledge and The physician will participate in EEG experience in the diagnosis, care and Greensboro NC is a growing community reading for the outpatient pediatric EEG treatment of pediatric stroke. Trainees of more than 280,000 people with a lab and the hospital system will have exposure to the Nationwide referral base of 500,000+, located in Leadership Duties: Childrens Stroke and Vascular Anomalies the central part of North Carolina. For The responsibilities of the leadership Clinic, as well as rotations through various weekend getaways, it is an easy drive team will include creating and sustaining departments within Nationwide Childrens aligned clinic culture, reducing and OSU.

116 Child Neurology Society | Fall 2020 Please visit our website for more sports teams and incredible metro park fostering and furthering the culture of information: system for any outdoor enthusiast. To compassion, collaboration, innovation, https://www.nationwidechildrens.org/ learn more about Cleveland, Ohio, visit accountability, diversity, integrity, for-medical-professionals/education-and- http://www.thisiscleveland.com/ quality, and trust that is integral to our training/fellowship-programs/pediatric- mission To Heal. To Teach. To Discover Interested individuals can apply for the stroke-fellowship position by sending their cover letter Contact: ______and curriculum vitae to Asim Shahid, Asim Shahid MD at [email protected]. ACADEMIC PEDIATRIC NEUROLOGIST [email protected] OPPORTUNITY, CLEVELAND, OHIO For additional information about the position, please contact him by email at The Division of Pediatric Neurology and [email protected]. Epilepsy at University Hospitals Rainbow CNS PERSONNEL REGISTRY Rainbow Babies & Childrens Hospital is Babies & Childrens Hospital in Cleveland OKLAHOMA a patient focused center distinguished Ohio is recruiting for a Pediatric Neurologist by collaboration, excellence, at the assistant professor level. The Pediatric THE CHILDREN’S HOSPITAL leadership, and respect. We value Neurologist will provide clinical care to OF SAINT FRANCIS candidates who are committed to children with complex neurological disorders SEE AD BELOW. working closely with a dynamic team of pediatric neurologists and epileptologists. Clinical activities will be carried out at Rainbow Babies & Childrens ambulatory and inpatient sites, and at University Hospitals outpatient clinics. The Pediatric Neurologist will be encouraged and supported to engage A CAREER THAT FULFILLS in investigation/research and scholarly activities. Opportunities exist to conduct YOUR LIFE'S PURPOSE. research in a variety of areas including clinical and translational research, education, outcomes/quality improvement, and medical informatics. There is infrastructure and PEDIATRIC support for clinical and translational research both within the Division and within the Department of Pediatrics. In addition to NEUROLOGIST clinical service and research responsibilities, there is an expectation for academic work MAKE A DIFFERENCE. including education, administration/service, BECOME PART OF THE TEAM. as well as advocacy. Qualified candidates must be Board Eligible/ Board Certified in Pediatric Neurology. The selected candidate will receive a faculty appointment at Case Western Reserve University School of Medicine at the academic level commensurate with experience and qualifications. University Hospitals offers a competitive salary and benefits program and productivity incentives. The Department offers faculty development and mentoring program designed to help faculty succeed in translational or basic research. The Cleveland area offers an incredible quality of life with a growing economy, rich cultural scene with ballet, theatre, 918-488-6021 symphony, opera and museums, SAINTFRANCIS.COM/CAREERS/PHYSICIANS outstanding restaurants, and a moderate cost of living. The city is well-known for its

EOE Protected Veterans/Disability

Child Neurology Society | Fall 2020 117 ______CNS PERSONNEL REGISTRY • Consistently growing pediatric volumes and a strong Network commitment to PEDIATRIC NEUROLOGIST PENNSYLVANIA expanding pediatric services within the St. Christopher’s Hospital for Children is community. seeking a full-time Pediatric Neurologist PEDIATRIC NEUROLOGIST • The Networks first Pediatric Intensive to join the hospital’s Section of Pediatric Care Unit opening in early 2020 at St. St. Lukes University Health Network, the Neurology. As a partnership between Lukes University Hospital, Bethlehem and region’s largest, most established health Tower Health and Drexel University, will receive admissions from all St. Lukes system, a major teaching hospital, and SCHC is a 188-bed, nonprofit facility that campuses. one of the nation’s 100 Top Hospitals provides exceptional care to children • The most robust and highest volume is seeking a passionate BC/BE Pediatric throughout the Greater Philadelphia area OB program in the region with a strong Neurologist to join our Pediatric and surrounding counties and suburbs of maternal and fetal medicine program Neurology practice providing excellent New Jersey. which delivers nearly 4,000 babies per care at St. Lukes University Health year. The applicant should have excellent Network. • 23 bed Level III NICU located at St. clinical and communication skills with a St. Lukes pediatrics department is Lukes University Hospital in Bethlehem, strong interest in teaching. Candidates growing and expanding our offering PA, 8 bed Level II NICU at St. Lukes with additional training in Epilepsy or of services. We are seeking providers Allentown Campus and NEW 26 bed Neurophysiology are welcome to apply who are excited by growth and new Level III NICU at St. Lukes Anderson for this position. opportunities. Join St. Lukes Pediatric Campus. The successful physician will possess a Neurology as our second pediatric • 11 hospital Network spread over a strong commitment to excellence in neurologist! Help us shape the future diverse geographic area providing delivery of care, research, education, of pediatric services in our region emergency care for over 317,000 and advocacy. The Section of Neurology through the addition of new pediatric patients annually. provides a full spectrum of outpatient subspecialists, new locations and • Opportunity to read EEGs from our and inpatient services, including inpatient increased inpatient capabilities! robust 11 hospital Network. video and ambulatory EEG services. In joining St. Lukes University Health About St. Lukes University HIGHLIGHTS: Network you’ll enjoy: Health Network: • The Section has a categorical 5-year • Substantial compensation and a Founded in 1872, St. Lukes University Child Neurology fellowship with two rich benefits package, including Health Network (SLUHN) is a fully fellows per year malpractice insurance, health and integrated, regional, non-profit network • An Academic affiliation through Drexel dental insurance, & CME allowance of more than 15,000 employees University College of Medicine with • Starting bonus and relocation providing services at 11 hospitals and 300 ample opportunities for teaching, assistance outpatient sites. With annual net revenue mentorship, and academic career • Work/life balance & flexibility greater than $2 billion, the Networks development • Team-based care with well-educated, service area includes 11 counties: Lehigh, • Opportunity to pursue research interests, dedicated support staff Northampton, Berks, Bucks, Carbon, in particular as they relate to our • A culture in which innovation is highly Montgomery, Monroe, Schuylkill and multicultural community and clinical valued Luzerne counties in Pennsylvania and setting • Professional support and growth Warren and Hunterdon counties in New • With more than 220 pediatric experts within the network Jersey. Dedicated to advancing medical on staff, SCHC combines top-notch • Teaching, research, quality education, St. Lukes is the preeminent pediatric care with a wide array improvement and strategic teaching hospital in central-eastern of pediatric specialties, including development opportunities Pennsylvania. Cardiology, ENT, GI, Oncology, and Contact: Orthopedics. Highlights include: • The only Verified Pediatric Only Burn • A growing pediatric specialty Christine Figler [email protected] Center between New York City and department currently spanning 12 Baltimore pediatric subspecialties and continuing • 1 of 3 Level I Pediatric Trauma Centers to expand in both depth and breadth in Pennsylvania of services. • Magnet® designated hospital and • Inpatient, primary care and specialty recognized as a Women’s Choice Award care providers across a variety of Best Children’s Hospital practice locations. The current inpatient unit is an 18 bed unit located For more information please contact: at St. Lukes University Hospital in Ellen Delgado Bethlehem, PA. Medical Staff Recruiter | 610-334-3394 [email protected] | towerhealth.org

118 Child Neurology Society | Fall 2020 CNS PERSONNEL REGISTRY CNS PERSONNEL REGISTRY • Earning potential above the 90th TENNESSEE TEXAS percentile of MGMA 10-bed epilepsy monitoring unit and active GENERAL PEDIATRIC NEUROLOGY, PEDIATRIC EPILEPTOLOGIST epilepsy surgery program (average 40 PRIVATE PRACTICE surgeries/yr) Child Neurology Epileptologist • Available technologies include Child Neurology Services, P.C., in Opportunity 3T and intraoperative-MRI, Knoxville, TN, is seeking an additional Cook Children’s Medical Center and Magnetoencephalography, PET, SPECT, board eligible/certified pediatric Health Care System, located in Ft. Worth, fMRI, TMS, and HD-EEG neurologist. TX, has initiated a national search for • Expertise in minimally invasive surgical Our independent, private practice a board certified/board eligible child procedures including Stereo-EEG, is associated with East Tennessee neurologist with subspecialty training in Laser Interstitial Thermal Ablation, and Children’s Hospital, a comprehensive clinical neurophysiology and/or epilepsy. Endoscopy medical center in the Tennessee • Specialty clinics for ketogenic diet, Cook Childrens Medical Center is a Valley with more than 100 pediatric genetic epilepsy, infantile spasms, and not-for-profit, free standing, 443-bed sub-specialists, including pediatric adult epilepsy transition of care quaternary care pediatric hospital that neurosurgery and genetics, serving • Dedicated Neuro-ICU with 10 rooms is consistently ranked by U.S. News and patients throughout the East Tennessee wired for EEG monitoring World Report. Although not academically region. affiliated, clinical research is an important 26-bed state-of-the-art Neuro- This is an opportunity to join a well- program component supported by Rehabilitation unit located next to the established practice due to an upcoming a multi-million dollar Neuroscience Neurosciences offices retirement. As the only neurology Research Endowment providing all • More than 25,000 patient encounters, practice in the area dedicated solely to necessary components for research 2300 evaluations for newly diagnosed pediatric patients, our child neurologists development, data acquisition, analysis, epilepsy, 1350 long term video-EEG and are committed to providing children and dissemination. Opportunities for over 3700 outpatient EEG in 2019 with mild to complex neurological teaching and faculty affiliation with the • First hospital in the country to establish conditions an exceptional level of care. University of North Texas Health Science dedicated Pediatric DBS program and We provide a mix of inpatient and Center and Texas Christian University to have Clearpoint Intraoperative iMRI outpatient care, including coverage of are also possible. For a closer look at our system the PICU, NICU, and hospital floors. We services please visit either of the following • Established comprehensive headache offer scheduled inpatient and outpatient websites:www.arcuate.org or www. program, stroke program, movement EEG monitoring. Call is shared equally cookchildrens.org/neurology disorder program, and genetic epilepsy by all four physicians. Cook Childrens is committed to securing clinic Knoxville offers a blend of small- an epilepsy specialist whose professional, Minimum qualifications: town southern charm and big-city social, and economic interests would lend Incumbent must have completed an opportunity. We are known for themselves to a long-term, cultural fit accredited pediatric specialty training our hospitality, affordability, and within the institution, the medical staff, program and be board certified/ convenience. Nestled in the foothills of and the community. The candidate will board eligible in child neurology the Great Smoky Mountains, Knoxville join a seasoned epilepsy team dedicated with subspecialty training in clinical sits on the banks of the Tennessee River to improving the care of children in our neurophysiology and/or epilepsy. and offers outdoor enthusiasts a wealth region through cutting-edge surgical Particular interest and training in epilepsy of possibilities. There are over 50 miles procedures, novel investigative trials, and surgery is preferred, with research of multi-use trails in the Knoxville Urban quality epilepsy care. experience favored. Wilderness and an expanding array of Other Programmatic Highlights: local breweries and restaurants, many Must be qualified to obtain an • Joining group of 18-Pediatric of which can be reached by Knoxville’s unrestricted Texas Medical License before Neurologists. Enjoy support from growing greenways. As a college town commencing employment. 8-Advanced Practice Providers, housing the University of Tennessee, • 4-Pediatric Neurosurgeons and Contact: this area offers great educational 3-Neuropsychologists. Enjoy an average Debbie Brimer opportunities and is a wonderful place of 4 call weekends per year and 2-3 [email protected] to raise a family and continue your weekday calls per month medical career. For confidential consideration, please forward your formal CV to jessica. [email protected].

Child Neurology Society | Fall 2020 119 TEXAS continued Foundation. Cook Childrens Medical an epilepsy monitoring unit at Covenant Center is a freestanding 443-bed Childrens Hospital. quaternary care pediatric hospital that ______Weekend and evening call coverage is consistently ranked by US News and limited to 1 in 4 weekends and evenings. PEDIATRIC HEADACHE FELLOWSHIP, World Report. The integrated system has BAYLOR COLLEGE OF MEDICINE more than 60 primary and specialty care Interested candidates will have faculty Baylor College of Medicine Department offices throughout North and West Texas, appointment and teaching opportunities of Pediatrics, Section of Child Neurology serving a 23-county referral network. with Texas Tech University providing offers a one year United Council for The Cook Children’s Physician Network instruction for medical students and Neurological Subspecialties (UCNS) is the largest pediatric multi-specialty neurology residents. accredited fellowship in headache physician group in its service area with Highly competitive compensation and medicine. It is currently the only over 600 employed specialty and primary benefits package including: headache fellowship program in care providers. Our focus, first and • Base salary at the 80th percentile. Houston, and one of few in the state. foremost, is delivery of easily accessible, • WRVU productivity-based incentive While it is a pediatric headache focused well-coordinated, comprehensive program. fellowship, adult neurology candidates evaluation and treatment for children with • Salary will be guaranteed for the first 2 may apply. neurological diseases through patient- years of employment. centered care. Although not a university- • Signing Bonus for qualified candidates. Contact: based program, clinical research is an Irene Patniyot important program component supported Covenant Childrens Hospital: [email protected] by a multi-million-dollar Neuroscience Covenant Childrens is part of Covenant ______Research Endowment providing Health, and its parent Providence-St all necessary elements for research Joseph Health, which has a history of OUTSTANDING CHILD development, data acquisition, analysis, over 100 years of service to the West NEUROLOGY OPPORTUNITY and dissemination. Texas/Panhandle Plains and eastern New Mexico region. Covenant Childrens is a On behalf of the Cook Children’s Health Key Programmatic Highlights: 275-bed facility and is the only licensed Care System (CCHCS) located in Dallas/ • Joining a specialized regional group freestanding children’s hospital in the Ft. Worth, Texas, CareerPhysician, a of 18-Child Neurologists, 8-Nurse area. CCH operates a level IV NICU and national leader in child health leadership Practitioners, 4-Pediatric Neurosurgeons, is verified as the only level II Pediatric consultation, is pleased to announce 1 Physiatrist and 3-Neuropsychologists Trauma Center in the region. CCH is also the inception of a national search for • Opportunity for appropriate candidates a regional provider of high-risk maternal qualified candidates to lead its newly to lead the groups Child Neurology care. CCH has over 175 physicians on created child neurology outreach efforts in West Texas medical staff, representing nearly all major location in Lubbock, TX. • Subspecialty support from Cook pediatric subspecialties (neurosurgery, Childrens Justin Neurosciences Center This position is part of a strategic neurology, cardiology, GI, ENT and ENT with nationally ranked programs in relationship between CCHCS and trauma, Endocrine, ID, Hem-Onc, Pulm, Epilepsy, DBS, Movement Disorders and Covenant Childrens Hospital in Lubbock. Adolescent Medicine, among others). The candidate will be responsible Headache for outpatient neurology care and • Access for your patients to a 10-bed CCH plays an active role in the West inpatient consultations at Covenant epilepsy monitoring unit and active Texas/Panhandle Plains regions provision Childrens Hospital. Subspecialty clinics epilepsy surgery program (average 40 of pediatric care via partnerships with for epilepsy and movement disorders surgeries/yr) with available technologies regional facilities, primarily in the Midland will be provided monthly by staff from including 3T and intraoperative-MRI, and Odessa area via providing pediatric the main campus with telemedicine Magnetoencephalography, PET, SPECT, hospitalist services for two hospitals. consultations available for additional fMRI, TMS, and HD-EEG on the main CCH has also begun to partner with neurological subspecialty care as campus. Texas Tech Health Sciences Center in required. Call responsibilities will be • Ability to follow your patient with access Amarillo. Historically, CCH has a close shared by Cook Childrens neurologists to a 26-bed state-of-the-art Neuro- relationship with Texas Tech University serving West Texas with additional call Rehabilitation unit located at main Health Sciences Center in Lubbock, with support from main campus faculty. campus in Fort Worth. CCH acting as the primary teaching site • Participate in established comprehensive for pediatric education for the Health CCHCS is a not-for-profit, nationally clinical and research programs in Sciences Center. Each year CCH trains recognized pediatric health care headache, stroke, movement disorder approximately 24 pediatric residents, with organization comprised of a Medical and epilepsy. many providers also serving as faculty of Center, Physician Network, Home TTUHSC, engaging in academic teaching, Health company, Pediatric Surgery If appropriate with interests and training, Center, Health Plan and Health ability over time to design and establish

120 Child Neurology Society | Fall 2020 and/or research. Qualifications: • Competitive Salary, Loan Forgiveness, • Board Certified or Board Eligible Relocation, and Outstanding Benefits Minimum qualifications: Pediatric Neurology • An innovative academic environment Incumbent must have completed an • US Citizen in partnership with the University of accredited pediatric specialty training Wisconsin Medical School means you program and be board certified/board Contact: can enjoy the best of practicing in an eligible in child neurology. Must be Stacey Ellis academic medical center --teaching and qualified to obtain an unrestricted Texas [email protected] research--in addition to patient care Medical License before commencing ______• In a Physician led organization based employment. on medical/administrative partnerships, SLEEP MEDICINE PHYSICIAN For more information about this managing all aspects of the business, outstanding position, please contact Childrens Specialty Group (CSG), PLLC you can have a voice in the way things Marcel Barbey, Vice President, is seeking a Sleep Medicine Physician to work at Gundersen CareerPhysician, at (817) 707-9034 or join our growing team of providers. The • We were the first health system in the via email at marcel@careerphysician. position offers inpatient and outpatient nation to offset 100 percent of our com for additional details. All inquiries care for newborn through young energy cost by renewable sources and and referrals are treated as and will adulthood. You will have the opportunity sustainable practices remain highly confidential without to work with a robust clinical research • We are a system with a 325-bed your prior approval. team in addition to teaching medical tertiary care center, regional hospitals, students and resident. Cook Childrens Health Care System is an clinics, nursing homes, air and ground ambulances, eye clinics, a behavioral affirmative action and equal opportunity The position offers the administrative health hospital and more employer of individuals with disabilities support of a large multi-specialty • Participate in Gundersen Medical and protected veterans. practice, competitive compensation, Foundation’s Global Partners Program, and a comprehensive benefits package working to create sustained connections that includes a 401k plan, profit sharing, with the Oglala Sioux Tribe on the health insurance, and professional liability CNS PERSONNEL REGISTRY Pine Ridge Reservation, S.D., and in coverage VIRGINIA Yetebon, Ethiopia, as well as engage CSG treat patients from southeastern in meaningful relationships with local PEDIATRIC NEUROLOGIST Virginia to northeastern North Carolina schools to foster resilience in students, as the sole providers of medical specialty teachers and families Bon Secours Mercy Health care at CHKD, the only free standing • Creating the life you want to lead. It’s Pediatric Neurology childrens hospital in Virginia. CSG is a about more than technology and patient Richmond, Virginia physician owned group whose mission is visits. It’s about joining a team that Bon Secours Mercy Health is seeking a to provide direct high-quality healthcare shares your passion, your vision, and full time Pediatric Neurologist to join to children and adolescents, train future your commitment. their team. Successful candidate will hit physicians, and conduct research to improve childrens health. La Crosse is a historic, vibrant city the ground running with a busy clinic nestled between bluffs and the legendary seeing between 12-15 patients a day. For more information, contact Michael Mississippi River. The region boasts great This is a clinical Pediatric Neurology Strunc, MD at Michael.Strunc@chkd. year-round outdoor recreation, excellent opportunity with no academic or org or visit our website csgdocs.com/ schools including three universities, research expectation. Physicians see careers. affordable housing in safe neighborhoods, a mix of cases including headaches, an endless variety of live entertainment epilepsy and a variety of movement and breathtaking beauty, making this a disorders. There is strong support from great place to call home. nurses, social work, and the pediatric CNS PERSONNEL REGISTRY sub-specialty program, including WISCONSIN Please contact Cathy Mooney, Medical Endocrinology, Gastroenterology, Staff Recruitment at camooney@ Pulmonology and Surgery. Pediatric EMPLOYED CHILD NEUROLOGY gundersenhealth.org Hospitalists and Pediatric Intensivists PRACTICE WITH GUNDERSEN HEALTH handle admissions and daily rounding The Department of Neurology at on in-patients. The clinic is located at St. Gundersen Health System, based in La Mary’s, a large community hospital that Crosse, Wisconsin, has an opportunity for has a dedicated Pediatric Emergency a Child/Pediatric Neurologist. You will join Department, NICU and PICU. Pediatric colleagues in a comprehensive pediatric sleep studies are available for children specialty practice, as well as colleagues in 3 years and older, as is home and Neurology and the Neurosciences. in-patient EEG monitoring and complete pediatric imaging services.

Child Neurology Society | Fall 2020 121 climate. Milwaukee is home to major $253 million was invested in research, WISCONSIN continued sports teams, a vibrant arts community, teaching, and training purposes, and a beautiful lakefront and county park more than 2,600 research studies were ______system, some of the best school systems conducted. MCW is also a large and in the nation and several Fortune 500 EMPLOYED CHILD NEUROLOGY growing educational center with three companies. Summer festivals and special OPPORTUNITY WITH GUNDERSEN campuses training over 1,000 medical events year-round make this a family HEALTH students and is in the top 5 percent friendly, culturally rich community. Join a Highly Collegial, Multispecialty, nationally in number of residents trained. Physician led Integrated Health System! Our Neurology group is the largest General Position Requirements: and most comprehensive in the state Board certified/eligible in Neurology with The emphasis is NOT on RVU, but on of Wisconsin, with residency programs a special certificate in child neurology putting patients first. We employ all of in Adult Neurology, Child Neurology, Eligible for medical licensure in Wisconsin our physicians, and also offer a unique Neuropsychology with fellowships in academic environment, affiliation and many subspecialty areas. Contact Info: faculty appointment possible with UW Matthew Harmelink, MD Madison’s School of Medicine. Children’s Wisconsin is a 296-bed Interim Division Chief, Child Neurology freestanding hospital and one of the Assistant Professor Competitive Salary, Loan Forgiveness, busiest pediatric hospitals in the country. Outstanding Benefits Director, Pediatric Neuromuscular Certified as a Level I Trauma Center, Program La Crosse, WI is located in the Driftless there are 13 inpatient units including a Director, Child Neurology Residency Region of SW Wisconsin, along the 72-bed PICU and a 70-bed Level IV NICU. Department of Neurology Upper Mississippi River, where an Our Pediatric Neurosciences Center is [email protected] outdoor lifestyle is complemented by the largest and most comprehensive in great locally grown food, and a thriving the state and ranks among the nation’s We are an Equal Opportunity Employer arts and music scene! best by U.S. News & World Report. Our and do not discriminate against any Epilepsy Center is a National Association employee or applicant for employment Contact: of Epilepsy Centers (NAEC) accredited because of race, color, sex, age, national Cathy Mooney Level 4 epilepsy center and allows us to origin, religion, sexual orientation, gender [email protected] provide the highest level of complex and identity, status as a veteran, and basis of ______specialized care for children living with disability or any other federal, state or epilepsy. The epilepsy monitoring unit is local protected class. CHILD NEUROLOGISTS a state-of-the-art evaluation center with The Department of Neurology at the 24-hour coverage by neurophysiology Medical College of Wisconsin (MCW) technicians and remote EEG reading and Children’s Wisconsin is seeking capabilities. Our subspecialty clinics board-certified/board-eligible child include: Epilepsy, First Seizure, Hypotonia, neurology specialists in both general Brachial Plexus, Neuromuscular with neurology and epilepsy. an MDA and PPMD care center, Neurogenetics and Fetal Concerns as well MCW is a major national research as a Pediatric Neurocritical Care Program center; the largest research institution in the Milwaukee metro area, and the Milwaukee is the cultural and economic second largest in the state of Wisconsin. hub of Wisconsin. The city boasts a In fiscal year 2017-2018, more than moderate cost of living and a four-season

122 Child Neurology Society | Fall 2020 CNS PERSONNEL REGISTRY Interested candidates should submit a CANADA current CV and a statement outlining their academic, teaching and research interests. PEDIATRIC NEUROLOGIST Candidates should also provide the names and contact information for three referees Pediatric Neurologist (1.0 FTE) (at least two of which must be academic). Dalhousie University & IWK Health Dalhousie University and the IWK Health Centre Centre are beautifully situated in the Halifax, Nova Scotia mature tree-lined South end of Halifax; a The Division of Neurology, in the short walk to downtown and the vibrant Department of Pediatrics at Dalhousie boardwalk along Halifax Harbour. Halifax University and the IWK Health Centre, is a rapidly growing cosmopolitan port invite applications for a full-time (1.0 city and the capital of Nova Scotia. The FTE) academic position as a Pediatric city is alive with culture, heritage, tourism Neurologist at the Assistant, Associate and embraced by the Atlantic Ocean. or Full Professor level. This individual Applications for this position will be will be one of a complement of 4 accepted until November 1, 2020 neurologists. The academic physician will primarily provide clinical service To apply for this position, please go to: across the full spectrum of pediatric http://dal.peopleadmin.ca neurology providing tertiary level care Dalhousie University is committed to for the only pediatric hospital serving fostering a collegial culture grounded in the Maritime Provinces. Expertise or diversity and inclusiveness. The university additional training in Neuromuscular encourages applications from indigenous disorders would be considered a strong persons, persons with a disability, asset. racially visible persons, women, persons The successful candidate will also be of a minority sexual orientation and/or expected to participate in research and/ gender identity, and all candidates who or teaching activities in an academic would contribute to the diversity of our environment; a developed interest community. in either would be considered an For more information, please visit https:// asset. The successful candidate will www.dal.ca/hiringfordiversity. be expected to participate in the on-call coverage for general pediatric Contact: neurology. Paula Brna [email protected] The applicant must have an MD or equivalent, and be board certified in Pediatric Neurology (Canadian FRCPC or eligibility), and be eligible for licensure in the Province of Nova Scotia.

Ads may be placed in the CNS Connections Deadline for placement in the next issue is December 1, 2020. AD magazine with rates for text-only ads beginning at $250. Graphic ads begin at $850 TO POST AN AD: PLACEMENT for 1/4 page (email/call for rates). Ads placed Go to www.childneurologysociety.org in newsletter may also be placed on CNS Click “Post a Position” Website for $75 ($275 for non-members).

Child Neurology Society | Fall 2020 123 TOGETHER•APART virtual OCTOBER 12-23,2020 2020

ICNA CNS ICNA CNS

16th International Child Neurology Congress 49th Annual Child Neurology Society Meeting

16th InternationalSharing Child Knowledge Neurology Congress 49thSowing Annual Friendships Child Neurology • Spreading Society HopeMeeting

Want CME Credit? Complete CME survey online immediately after the meeting: October 23-November 2