FRIDAY, NOVEMBER 1st, 2019

09:00-20:30 Arrival & Registration

18:00-20:00 Dinner

SATURDAY, NOVEMBER 2nd, 2019 08:30-12:00

Building No. 3, Meeting Room No. 1

Opening Ceremony 08:30-08:55 Chaired by Guochen Zhang (Vice President of Dalian Ocean University)

Welcoming Address by Jie Yao (Chairman of Dalian Ocean University 08:30-08:35 Council) Address by Daigang Yang (Chairman of Dalian Association for Science and 08:35-08:40 Technology Council)

Address by L. Courtney Smith (President of International Society of 08:40-08:45 Developmental and Comparative Immunology)

Address by Linsheng Song (President of Asian Society of Developmental and 08:45-08:50 Comparative Immunology) Conferring the Certificate of Honorary President and Vice President of 08:50-08:55 ASDCI

08:55-09:10 Group Photo

Plenary Lecture 09:10-12:00 Chaired by Linsheng Song and Miki Nakao L. Courtney Smith (George Washington University, USA) 09:10-09:50 Sequence diversity in the genes and proteins of the SpTransformer system in sea urchins Kenneth Söderhäll 09:50-10:30 (Uppsala University, Sweden) Blood cell synthesis in a crustacean

10:30-10:40 Break

Yaofeng Zhao ( Agricultural University, China) 10:40-11:20 Immunoglobulins in tetrapod other than human and mouse: surprises and applications Maria Forlenza 11:20-12:00 (Wageningen University, Netherlands) Trypanosome infections in Zebrafish: seeing is believing

12:00 Lunch

SATURDAY, NOVEMBER 2nd, 2019

14:00-17:35 Building No. 5, Building No. 5, Building No. 1, Room 402 Multi-function Hall Meeting Room No. 5 Session 1 Session 2 Session 3 Evolution and origins of Innate Immunity Ecoimmunology and immune system immunometabolism

Chaired by L. Courtney Chaired by Kenneth Chaired by Liangbiao Smith and Shicui Zhang Söderhäll and Jinxing Chen and Wuhan Xiao Wang Invited Lecture Invited Lecture Invited Lecture Jianhai Xiang Jinxing Wang Wuhan Xiao (Institute of Oceanology, (Shandong University, (Institute of Hydrobiology, Chinese Academy of China) Chinese Academy of Sciences, China) Sciences, China)

14:00-14:25 A comprehensive view of the Regulation of microbiota Zebrafish phd3 negatively immunity characteristics of homeostasis in shrimp regulates antiviral response the shrimp (Litopenaeus via suppression of Irf7 vannamei) and the sea transactivity independent cucumber (Apostichopus of its prolyl hydroxylase japonicas) by digging their activity genome data Heng Chi Suparat Taengchaiyaphum Hao Chen (Ocean University of China, (National Center for Genetic (Institute of Oceanology, China) Engineering and Chinese Academy of Biotechnology, Thailand) Sciences, China)

14:25-14:40 The regulatory functions of The roles of antimicrobial Synergistical modulation of transcription factor GATA-3 peptides in shrimp survived Ca2+/CaM-NOS-TNF during the Th2-like response WSSV infection pathway by multiple in Atlantic salmon (Salmo microRNAs hallmarks salar) resistance of oyster against aerial exposure Zhujin Ding Cuiluan Yao Qingguo Meng ( Ocean University, (Jimei University, China) (Nanjing Normal China) University, China)

Identification and expression TAB2 is critical for TAK1 Spiroplasma eriocheiris analysis of an intelectin gene and TRAF6-mediated NF-κB invasion into 14:40-14:55 from Megalobrama activation in large yellow Macrobrachium amblycephala and its croaker rosenbergii hemocytes is regulation on the mediated by pathogen phagocytosis and killing enolase and host activity of macrophages lipopolysaccharide and β-1, 3-glucan binding protein Sheng Wang Fan Mao Phasini Buathongkam (Sun Yat-Sen University, (South China Sea Institute of (National Center for 14:55-15:10 China) Oceanology, Chinese Genetic Engineering and Academy of Sciences, Biotechnology Thailand) China)

WSSV establishes a novel Learning from survivors of IE1/JNK/c-Jun positive Phagosomal proteomics to white spot syndrome virus feedback loop to drive viral study invertebrate outbreak replication phagocytosis in Crassostrea gigas Mofei Li Junfeng Xie Hongtao Nie (Institute of Oceanology, (Sun Yat-Sen University, (Dalian Ocean University, Chinese Academy of China) China) Sciences, China)

The teleost complement Protein A from Transcriptome analysis 15:10-15:25 factors involved in the orange-spotted nervous reveals differential immune regulation of complement necrosis virus triggers type I related genes expression in activation and immune cell interferon production in fish Ruditapes philippinarum activity cell via under hypoxia stress RIG-I/MDA5-MAV S -IRF3 signal pathway

15:25-16:25 Break & Poster (Building No. 5, Multi-function Hall)

Invited Lecture Invited Lecture Invited Lecture Shaochun Yuan Hai-peng Liu Jian He (Sun Yat-Sen University, (Xiamen University, China) (Sun Yat-Sen University, China) China) 16:25-16:50 Functional characterization White spot syndrome virus The replication of of the ancestral RAG infection in a crustacean infectious spleen and transposon sheds new lights kidney necrosis virus was on the origin and evolution promoted under hypoxia of V(D)J recombination Xianghui Kong Tianming Wang Jianguo Su (Henan Normal University, (Zhejiang Ocean University, (Huazhong Agricultural China) China) University, China) Molecular characteristics of Discover the KISS/GPR54 MxG negatively regulates 16:50-17:05 pIgR in grass carp signaling system in sea type I interferon by (Ctenopharyngodon idella) cucumber targeting IPS-1 and STING and comparative analysis in grass carp between the different animals Bei Wang Haoyang Li Guilan Di (Guangdong Ocean (Sun Yat-Sen University, (Henan Normal University, University, China) China) China) 17:05-17:20 Insights into the evolution of STING dsDNA sensing Phagocytosis of different the suppressors of cytokine induces IRF-Vago antiviral haemocyte subpopulations signaling (socs) gene family mechanism in shrimp of Babylonia areolata in vertebrates Xinyu Jiang Weiwei Li Ruijun Li (Henan Normal University, (East China Normal (Dalian Ocean University, China) University, China) China)

17:20-17:35 Distinct expression profiles The antibacterial response of Immune defense enzymes: and overlapping functions of Chinese mitten crab Advances in L-amino acid IL-4/13A and IL-4/13B in oxidase of marine animals grass carp (Ctenopharyngodon idella) 18:00-20:00 Dinner

SUNDAY, NOVEMBER 3rd, 2019 08:30-12:00

Building No. 5, Building No. 5, Building No. 1, Room 402 Multi-function Hall Meeting Room No. 5

Session 1 Session 2 Session 3 Evolution and origins of Innate Immunity Ecoimmunology and immune system immunometabolism

Chaired by Pin Nie and Chaired by Maria Forlenza Chaired by Qinghui Ai and Geert F. Wiegertjes and Fuhua Li Bo Peng

Invited Lecture Invited Lecture Invited Lecture Geert F. Wiegertjes Fuhua Li Bo Peng (Wageningen University, (Institute of Oceanology, (Sun Yat-Sen University, 08:30-08:55 Netherlands) Chinese Academy of China) Sciences, China)

Evidence of trained The hemocytes mediated Reactivation of glycine immunity in fish innate immunity in shrimp metabolism to eliminate macrophages serum-resistant bacteria Qian Ren Xianwei Wang Kallaya Sritunyalucksana (Nanjing Normal University, (Shandong University, (National Center for Genetic China) China) Engineering and Biotechnology, Thailand) 08:55-09:10 Evolution of invertebrate Maturation of a new Avoiding false-positive immune system: gene antimicrobial peptide inhibits shrimp-virus PCR tests replication, domain doubling Aeromonas hydrophila results that arise from and horizontal transfer infection in red swamp endogenous viral elements crayfish Procambarus clarkii (eves) Junya Wang Hao Wang Songzhe Fu (Shanghai Ocean University) (Institute of Oceanology, (Dalian Ocean University, Chinese Academy of China)

Sciences, China) 09:10-09:25 Structure of grass carp Adapt to extreme Safety assessment of interleukin-2 provides environment: How the animal-use probiotics as an insights into the evolution of deep-sea mussel cope with immune booster: two case four α-helical cytokine symbiotic bacteria studies family Graduate Student Lecture Graduate Student Lecture Graduate Student Lecture Xiaowei Qin Dongli Li Xingjuan Wang (Sun Yat-Sen University, (Xiamen University, China) (Hainan University, China) China)

The roles of mandarin fish Cqβ-actin binding protein Coral lectin implicates in the 09:25-09:40 STING in innate immune Cqprofilin promotes white immunity and symbiosis defense against infectious spot syndrome virus with Symbiodinium spleen and kidney necrosis replication via interacting virus infection with viral nucleocapsid protein vp15 in red claw crayfish Cherax quadricarinatus Graduate Student Lecture Graduate Student Lecture Graduate Student Lecture Nehlah Rosli Yan Gao Libo Hou (Faculty of Agriculture, (Huazhong Agricultural (Nanjing Normal University, Department of Bioscience University, China) China) and Biotechnology, Japan)

09:40-09:55 Functional analysis of two The antiviral mechanism of The role of Wnt signaling complement C4 isotypes of viperin and its splice variant pathway in the process of carp using recombinant in spring viremia of carp Spiroplasma eriocheiris proteins virus infected fathead infected the Eriocheir minnow cells sinensis and caused the Tremor disease

09:55-10:20 Break

Invited Lecture Invited Lecture Invited Lecture Yinglun Han Lingling Wang Liqun Lv (Liaoning Normal (Dalian Ocean University, (Shanghai Ocean University, 10:20-10:45 University, China) China) China) Embryological stages in the The immune recognition Stress response of fish lamprey mechanism in molluscs contributes to viral disease outbreak: a study from grass carp reovirus Graduate Student Lecture Graduate Student Lecture Graduate Student Lecture Libing Xu Ruoyun Zeng Lingke Liu (Fujian Agriculture and (Sun Yat-Sen University, (Xiamen University, China) Forestry University, China) China)

Molecular cloning and Deletion of infectious spleen A histone K-lysine 10:45-11:00 functional characterization of and kidney necrosis virus acetyltransferase c-Jun in large yellow croaker ORF022L reduces virus Cqkat2a-like gene promotes (Larimichthys crocea) virulence and induces white spot syndrome virus protection against challenge infection by enhancing in mandarin fish histone h3 acetylation in red claw crayfish Cherax quadricarinatus Graduate Student Lecture Graduate Student Lecture Graduate Student Lecture Liguo Ding Zeinab Hassan Ahmed Zhuang Wang (Huazhong Agricultural Elsayed (East China University of University, China) (Shanghai Ocean University, Science and Technology, 11:00-11:15 China) China )

Pharyngeal immunity in Characterization of Identification the teleost fish, an ancient interleukin-20 and IL-20 inflammasome component mucosal defense to combat receptor α in grass carp SmASC in Scophthalmus parasitic infection (Ctenopharyngodon idella) maximus L. Graduate Student Lecture Graduate Student Lecture 11:15-11:30 Graduate Student Lecture Kun Cui Bang Xiao Yunfei Ding (Ocean University of China, (Sun Yat-Sen University, (Binzhou Medical China) China) University, China) Establishment and Penaeidins restrict white spot The influence of characterization of two head syndrome virus infection by nano-plastics on gastric kidney macrophage cell lines antagonizing the envelope epithelial cells from large yellow croaker proteins to block viral entry (Larimichthys crocea) Graduate Student Lecture Graduate Student Lecture Graduate Student Lecture Zaichao Zheng Yanyun Guan Honghui Li (Third Institute of (Fujian Agriculture and (Changsha University, Oceanography, Ministry of Forestry University, China) China) Natural Resources, China)

Regulation of hemocyte Molecular characterization Protective effect and 11:30-11:45 homeostasis in crayfish: the and expression analysis of mechanism of role of gill eleven interferon regulatory N-acetylcysteine on factors (IRFs) in the oxidative stress and perciform fish, large yellow autophagy in muscle induced croaker (Larimichthys by infection of Proteus crocea) vulgaris from Chinese soft-shelled turtle (Pelodiscus sinensis) Graduate Student Lecture Graduate Student Lecture Graduate Student Lecture Yueyi Wang Xiangyu Zhang Jun Yang (Zhejiang University, China) (South China Sea Institute of (Sun Yat-Sen University, Oceanology, Chinese China)

11:45-12:00 Academy of Sciences, Identification of an NLRP1 China ) inflammasome in teleost fish reveals a unique mechanism The critical role of chloride Metabolic mechanism by for inflammatory caspase ion influx in phagocytosis which L leucine-induced activation and IL-1 and bactericidal activity in metabolome eliminates maturation Crassostrea gigas Streptococcus iniae

12:00-13:30 Lunch

SUNDAY, NOVEMBER 3rd, 2019 14:00-18:00

Building No. 5, Building No. 5, Building No. 1, Room 402 Meeting Room No. 5 Multi-function Hall

Session 2 Session 3 Session 4 Innate Immunity Ecoimmunology and Adaptive Immunity and immunometabolism Vaccines

Chaired by Kallaya Chaired by Yongan Zhang Chaired by Qiwei Qin and Sritunyalucksana and Jun and Xinhua Chen Zhen Xu Zou Invited Lecture Invited Lecture Invited Lecture Jun Zou Xinhua Chen Zhen Xu (Shanghai Ocean University, (Fujian Agriculture and (Huazhong Agricultural 14:00-14:25 China) Forestry University, China) University, China) The interferon mediated Function and signal The novel function of antiviral response is pathways of large yellow mucosal IgT in teleost positively regulated by croaker (Larimichthys against virus infection IRF2a in zebrafish crocea) interleukin-2 Dahai Yang Hui Li Jialong Yang (East China University of (Sun Yat-Sen University, (East China Normal Science and Technology, China) University, China) China) 14:25-14:40 Zebrafish GSDMEb Myo-inositol improves the Regulatory mechanisms of T cleavage gates the pyroptosis host’s ability to eliminate cell immunity in teleost enhances septic-AKI in vivo balofloxacin-resistant Escherichia coli Graduate Student Lecture Graduate Student Lecture Jie Gao Zheng Xu Yingying Li (Shandong University, (Binzhou Medical (Liaoning Normal China) University, China) University, China) 14:40-14:55 MD-2 homologue recognizes Helicobacter pylori regulates Mechanism on the lamprey the white spot syndrome ILK to influence autophagy adaptive immune system virus lipid component and through Rac1/F-actin and development regulated by induces antiviral molecule RhoA/F-actin signaling intestinal Aeromonas expression in shrimp pathways in gastric epithelial cell Graduate Student Lecture Graduate Student Lecture Graduate Student Lecture Ming Jiang Shuo Han Yu Zhang (Sun Yat-Sen University, (Dalian Ocean University, (East China Normal China) China) University, China) 14:55-15:10 Phenylalanine modulates Comparative MAPK/ERK regulates Nile innate immune of Danio Characterization of bacterial tilapia adaptive immunity via rerio to clear ceftazidime communities in digestive controlling lymphocyte resistant Vibrio alginolyticus glands of Crassostrea gigas activation, proliferation and fed with different diets infection elimination Graduate Student Lecture Graduate Student Lecture Graduate Student Lecture Yue Lin Yu Tang Cheng Li (South China Sea Institute of (Zhejiang University) (East China Normal Oceanology, Chinese University, China) Academy of Sciences, China )

15:10-15:25 Transcriptomic analyses the Immunotoxicity of Teleost employs IL-17 molecular mechanism of microplastics and triggered NF-κB signaling to hemocyte-mediated benzo[a]pyrene alone or in regulate ancestral T cell phagocytosis in Crassostrea combination to a bivalve immunity against hongkongensis species: Particle size Streptococcus agalactiae dependent interactions and infection potential underlying mechanism Graduate Student Lecture Graduate Student Lecture Graduate Student Lecture Pengfei Mu Md Hasim Rabbi Zhiwen Wang (Fujian Agriculture and (Dalian Ocean University, (Guangdong Ocean Forestry University, China) China) University, China) 15:25-15:40 Regulation of Large Yellow Effects of dietary selenium Functional analysis of CD6 Croaker (Larimichthys (Se) and vitamin C (Vc) on of Nile tilapia (Oreochromis crocea) Interleukin-2 growth, digestion, immunity niloticus) and selenium content of the juvenile sea cucumber (Apostichopus japonicus) 15:40-16:00 Break Linlin Zhang Xinjiang Lu Jianmin Ye (Institute of Oceanology, (Ningbo University, China) (South China Normal Chinese Academy of University, China) Sciences, China) 16:00-16:15 Gene duplication and The subfunctionalization of The role of long-lived functional divergence of chemokine receptors in plasma cells in oyster innate immune genes teleost immunological memory in teleosts Yu Huang Jiejie Sun Chao Pei (Guangdong Ocean (Dalian Ocean University, (Henan Normal University, University, China) China) China ) Serotransferrin and C-type An ancient BCR A developed subunit vaccine 16:15-16:30 lectin could mediated NCC molecule-mediated signaling based on fiber protein VP56 activity by interacting with promotes the production of of grass carp reovirus NCCRP-1 in Nile tilapia immunoglobulin providing immune protection (Oreochromis niloticus) domain-containing proteins against grass carp and hemocyte phagocytosis hemorrhagic disease in oyster Pengfei Liu Xingkun Jin Xiaoxue Yin (Dalian Ocean University, (, China) (South China Normal China) University, China)

16:30-16:45 ALDH7A1 is a protein that Transcriptome-wide analysis TNP-specific antigen protects Atlantic salmon of immune responses in induces the oligomannose against Aeromonas Eriocheir sinensis hemocytes modification of IgM heavy salmonicida at the early after challenge with different chain in Nile tilapia stages of infection microbial derivatives (Oreochromis niloticus) Hengwei Deng Shouwen Chen Jie Zhang (Sun Yat-Sen University, (East China University of (Henan Normal University, China) Science and Technology, China ) China )

16:45-17:00 The NF-κB family member Scophthalmus maximus Transcriptome analysis of Dorsal is involved in interleukin-1β limits Qihe crucian carp (Carassius resistance against Edwardsiella piscicida auratus) in response to gram-positive bacterial colonization in vivo Aeromonas hydrophila infection in Scylla paramamosain Closing Ceremony (Building No. 5, Multi-function Hall) 17:30-18:00 Chaired by Lingling Wang (Secretary of Asian Society of Developmental and Comparative Immunology)

17:30-17:40 Announcement of Oral & Poster Awards

17:40-17:45 Closing address by Lingling Wang

th 17:45-18:00 Introduction of the 15 Congress of ISDCI by Maria Forlenza (Secretary of International Society of Developmental and Comparative Immunology)

18:00-20:00 Dinner

MONDAY, NOVEMBER 4th, 2019 08:00-10:30

08:00-10:30 Visit to Aquaculture Company