A, Proton-Density Weighted. B, T2-Weighted. C, DEC-DTI. D, Anatomic Schematic

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ON-LINE FIG 1. Middle pons. Upper row: A, Proton-density weighted. B, T2-weighted. C, DEC-DTI. D, Anatomic schematic. Lower row: E, EMC PD map. F, EMC T2 map. G, stDEC-TDI. H, stTDI. Due to super-resolution, stTDI maps can distinguish the trigeminal nerve fascicles (45) from the middle cerebellar peduncles (42) better than DEC-DTI. Notice how at the same axial section plane, the EMC PD image better depicts the motor nucleus of the trigeminal nerve (45), and the medial lemnisci (15) and spinothalamic tract (26) are more conspicuous on the EMC T2 image. This depiction emphasizes that multicontrast imaging is best suited to confidently discriminate internal brain stem anatomy. ON-LINE FIG 2. Caudal pons. Upper row: A, Proton-density weighted. B, T2-weighted. C, DEC-DT. D, Anatomic schematic. Lower row: E, EMC PD map. F, EMC T2 map. G, stDEC-TDI. H, stTDI. EMC PD maps are able to depict the nucleus solitarius (49), whereas the conventional PD image cannot. The spinal tract and nucleus of the trigeminal nerve (51) can be seen at this level for the first time on both stTDI maps, which may prove useful for future quantitative research in patients with trigeminal neuralgia. AJNR Am J Neuroradiol ●:●●2016 www.ajnr.org E1 On-line Table: Labeled brain stem anatomy key Key 1) Cingulate gyrus 2) Corpus callosum 3) Fornix 4) Subgenual cingulate gyrus 5) Anterior commissure 6) Posterior commissure 7) Subthalamic fields of Forel 8) Tectum of midbrain 9) Decussation of superior cerebellar peduncles 10) Medial cerebral peduncle 11) Optic nerve 12) Cerebellar folia 13) Superior cerebellar peduncle 14) Transverse pontocerebellar fibers 15) Medial lemniscus 16) Pyramidal tract 17) Central tegmental tract 18) Cerebellar tonsil 19) Inferior medullary olive 20) Fasciculus cuneatus 21) Oculomotor nerve fascicles 22) Frontopontine fibers 23) Occipitotemporal and parietopontine fibers 24) Rubrospinal tract 25) Ventral trigeminothalamic tract 26) Spinothalamic tract 27) Spinotectal tract 28) Superior colliculus 29) Periaqueductal gray 30) Midbrain reticular formation 31) Red nucleus 32) Substantia nigra 33) Oculomotor nuclear complex 34) Medial longitudinal fasciculus 35) Interpeduncular fossa 36) Caudal fascicles of oculomotor nerve 37) Cerebral peduncle 38) Aqueduct of Sylvius 39) Inferior colliculus 40) Lateral lemniscus 41) Pontine nuclei 42) Middle cerebellar peduncle 43) Locus coeruleus 44) Superior medullary velum 45) Trigeminal nerve fascicles 46) Motor nucleus of trigeminal nerve 47) Dorsal trigeminothalamic tract 48) Pontine reticular formation 49) Nucleus solitarius 50) Facial nerve fascicles 51) Spinal nucleus and tract of trigeminal nerve 52) Medullary reticular formation 53) Inferior cerebellar peduncle 54) Fourth ventricle 55) Hypoglossal nucleus 56) Dorsal motor nucleus of vagus nerve 57) Vestibular nuclei 58) Spinal tract of trigeminal nerve 59) Ventral median sulcus 60) Spinocerebellar tract 61) Internal arcuate fibers 62) Central gray matter 63) Nucleus gracilis 64) Nucleus cuneatus E2 Hoch ● 2016 www.ajnr.org.

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Characterization of Age-Related Microstructural Changes in Locus Coeruleus and Substantia Nigra Pars Compacta
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