S C I E N T I F I C P R O G R a M M E
FEDERATION OF EUROPEAN BIOCHEMICAL SOCIETIES UKRAINIAN BIOCHEMICAL SOCIETY POLISH BIOCHEMICAL SOCIETY ISRAEL SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY
S C I E N T I F I C P R O G R A M M E
OF THE FEBS3+ MEETING - XI PARNAS CONFERENCE
‘BIOCHEMISTRY AND MOLECULAR BIOLOGY FOR INNOVATIVE MEDICINE’
3 – 5 September 2018
Kyiv, UKRAINE ORGANIZERS
Ukrainian Biochemical Polish Biochemical Israel Society for Society (UBS) Society (PBS) Biochemistry and Molecular Biology (ISBMB)
PARTNERS
National Academy of Sciences (NAS) of Ukraine Ministry of Science and Education of Ukraine Taras Shevchenko National University of Kyiv Palladin Institute of Biochemistry of NAS of Ukraine
MAIN SPONSOR
Federation of European Biochemical http://www.febsjournal.org/ Societies (FEBS) http://www.febsletters.org/ 'Supported by the FEBS3+ http://www.febsopenbio.org/ Meeting programme' http://www.moloncol.org/
SPONSORS
“Ecofarm” ALT Ukraine
Dear participants of the FEBS3+ Meeting – XIth Parnas Conference – Young Scientists Forum ‘Biochemistry and Molecular Biology for Innovative Medicine’!
On behalf of the Organizing Committee of the XIth Parnas Conference it’s my honour and pleasure to greet you and to invite you to join the PARNAS Conference-2018 in Kyiv, the beautiful capital of our country. Welcome to Ukraine! Many things have been changed in the world and in Biology since the first Parnas Conference in 1996 in Lviv, and the Conference itself has been changed. During these 22 years, the Parnas Conference became an International scientific forum organized now by three societies – Ukrainian Biochemical, Polish Biochemical and Israel Society for Biochemistry and Molecular Biology. Though these three societies serve alternatively as hosts, the Parnas Conference was never considered being a close trilateral event but a wide and open International Conference with a special emphasis on young scientists. Since the last Conference in Wroclaw in 2016 the Parnas Conference became a Young Scientists Forum with financial support of FEBS and as the FEBS3+ Meeting. General opinion is that all ten previous Parnas conferences were successful, and I wish to thank all my colleagues who had contributed so much in the organization of these conferences. In particular, I wish to express our deep gratitude to Professor Rostyslav Stoika who had initiated Parnas Conferences, to Professor Andrzej Dzugaj and Professor Jolanta Baranska – former presidents of the Polish Biochemical Society, to Professor Michael Eisenbach, former President of the Israel Society for Biochemistry and Molecular Biology as well as to Professor Israel Pecht – former FEBS General Secretary and Professor Adam Szewczyk – for mer FEBS Congress Counsellor for their support and contribution into the Parnas Conferences organization. Almost everybody at our Conference is well aware why it bears the name of Jakub Parnas (1884-1949). But still I wish to remind that this outstanding scholar was born in Austro-Hungarian Empire in a village in Drogobytch region, which is in recent Ukraine but after the First WW became in Poland, was studying sciences in Germany, France and Switzerland, and was working in France and in Poland (in Warsaw and mainly in Lviv) until 1939. In all fairness, he is considered to be the founder of Polish Biochemistry. Due to the known events in 1939 Parnas became a Soviet citizen still living and working in Lviv (in the then Ukrainian Soviet Socialist Republic) until 1941 when Nazis occupied Lviv, and he was evacuated to Ufa and later to Moscow. For some time in Ufa he was collaborating with our Institute of Biochemistry, which was evacuated there from Kyiv during the WW II. Due to his outstanding contribution to Biochemistry Parnas was highly estimated in the Soviet Union being elected to the USSR Academy of Sciences and Academy of Medical Sciences and decorated with highest awards. But it was USSR under Stalin and on January 28, 1949 he was arrested by KGB and next day died in KGB prison because of diabetes crisis or heart attack. Indeed it was a personal tragedy but also a huge loss for the world’s science. That’s why establishing the Parnas Conferences on modern Biochemistry is our Biochemical Societies’ homage to this great scholar and personality. Please allow me again, on behalf of the Organizing Committee, to wish you all fruitful and enjoyable stay in Kyiv. Yours sincerely
Professor Serhiy Komisarenko President of the Ukrainian Biochemical Society, Chairperson of the Organizing Committee
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PARNAS CONFERENCE ORGANIZING COMMITTEE
Conference Honorable Chairpersons Prof. Boris Paton, President, National Academy of Sciences of Ukraine Dr. Liliya Grinevitch, Minister for Education and Science of Ukraine Prof. Leonid Guberskiy, Rector, Taras Shevchenko National University of Kyiv, Ukraine Prof. Jerzy Duszynski, President Polish Academy of Sciences, Poland Prof. Israel Pecht, Former FEBS General Secretary, Israel
Conference Scientific and Program Committee Chairperson Prof. Serhiy Komisarenko, President, Ukrainian Biochemical Society, Director, Palladin Institute of Biochemistry, Ukraine Co-Chairpersons Prof. Andrzej Legocki, President, Polish Biochemical Society, Poland Prof. Andrzej Dzugaj, Ex-President, Polish Biochemical Society, Poland Dr. Dana Reichmann, Hebrew University of Jerusalem, Israel Prof. Victor Martynyuk, Vice-Rector, Taras Shevchenko National University of Kyiv, Ukraine Prof. Ganna Elska, Director, Institute of Molecular Biology and Genetics, Ukraine Prof. Liudmila Ostapchenko, Taras Shevchenko National University of Kyiv, Ukraine
Symposium Chairpersons Prof. Adam Szewczyk, Nencki Institute of Experimental Biology, Poland Prof. Grzegorz Węgrzyn, University of Gdańsk, Poland Prof. Andrzej Sybirny, University of Rzeszow, Poland-Ukraine Prof. Gideon Schreiber, The Weizmann Institute of Science, Israel, Dr. Shenhav Cohen, Technion-Israel Institute of Technology, Israel Dr. Dana Reichmann, Hebrew University of Jerusalem, Israel Prof. Sergiy Kosterin, Palladin Institute of Biochemistry, Ukraine Prof. Rostyslav Stoika, Institute of Cell Biology, Ukraine Prof. Valeriy Filonenko, Institute of Molecular Biology and Genetics, Ukraine
Poster Session Co-Chairpersons Prof. Rostyslav Stoika, Institute of Cell Biology, Ukraine Prof. Maryna Skok, Palladin Institute of Biochemistry, Ukraine Prof. Mykola Veliky, Palladin Institute of Biochemistry, Ukraine Prof. Olga Matyshevska, Taras Shevchenko National University of Kyiv, Ukraine Prof. Ganna Tolstanova, Taras Shevchenko National University of Kyiv, Ukraine Dr. Volodymyr Chernyshenko, Palladin Institute of Biochemistry, Ukraine
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CONFERENCE VENUE
Registration
September 03, 09:00 – 17:00 Hall, Palladin Institute of Biochemistry of NAS Ukraine, Kyiv, 9 Leontovycha St.
September 04, 08:30 – 13:30 aud. 201, Main Building, Taras Shevchenko National University of Kyiv, Kyiv, 60 Volodymyrska St.
Opening ceremony
September 03, 17:00 – 19:00 Assembly Hall, Main Building, Taras Shevchenko National University of Kyiv, Kyiv, 60 Volodymyrska St.
Main venue
September 04, 09:00 – 18:30 aud. 329, Main Building, Taras Shevchenko National University of Kyiv, Kyiv, 60 Volodymyrska St.
September 05, 09:00 – 17:30 aud. 329, Main Building, Taras Shevchenko National University of Kyiv, Kyiv, 60 Volodymyrska St.
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PROGRAMME OUTLINE
DAY 1. MONDAY, SEPTEMBER 3
Venue: Palladin Institute of Biochemistry of NAS Ukraine, 9 Leontovycha St. 09:00 – 17:00 Registration (Hall) 15:00 – 16:30 Workshop (Assembly Hall, 3rd floor)
Venue: Taras Shevchenko National University of Kyiv, Main Building, 60 Volodymyrska St. 17:00 – 19:00 Opening ceremony, Plenary lecture-1, Welcome concert (Assembly Hall) 19:00 – 20:30 Get-together party (hall in front of the Assembly Hall, 2nd floor)
DAY 2. TUESDAY, SEPTEMBER 4
Venue: Taras Shevchenko National University of Kyiv, Main Building, 60 Volodymyrska St. 08:30 – 13:30 Registration (aud. 201) 08:30 – 09:00 Preparation of posters for presentation, 1-01 – 1-64 (hall in front of the Assembly Hall, 2nd floor)
Symposium I. ‘Intracellular signalling’ (aud. 329) 09:00 – 09:30 Key-note lecture-1 09:30 – 10:30 Oral presentations (3)
10:30 – 11:30 POSTER SESSION – 1 & COFFEE/TEA BREAK (hall in front of the Assembly Hall, 2nd floor)
Symposium II. ‘The biochemistry of the cell’ (aud. 329) 11:30 – 12:30 Oral presentations (3)
Symposium III. ‘Сell signalling in cancer’ (aud. 329) 12:30 – 13:30 Oral presentations (3)
13:30 – 14:30 LUNCH BREAK
Symposium IV. ‘Ligand-receptor binding in cell functions and drug development’ (aud. 329) 14:30 – 15:00 Key-note lecture-2 15:00 – 16:00 Oral presentations (3)
16:00 – 16:30 COFFEE/TEA BREAK (hall in front of the Assembly Hall, 2nd floor)
Symposium V. ‘From cell to organism’ (aud. 329)
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16:30 – 17:30 Key-note lecture-3, Key-note lecture-4 17:30 – 18:30 Oral presentations (3)
DAY 3. WEDNESDAY, SEPTEMBER 5
Venue: Taras Shevchenko National University of Kyiv, Main Building, 60 Volodymyrska St. 08:30 – 09:00 Preparation of posters for presentation 2-01 – 2-64 (hall in front of the Assembly Hall, 2nd floor)
Symposium VI. ‘Molecular biology of bacteria and viruses’ (aud. 329)
09:00 – 10:00 Oral presentations (3)
10:00 – 11:00 POSTER SESSION – 2 & COFFEE/TEA BREAK (hall in front of the Assembly Hall, 2nd floor)
Symposium VII. ‘Metabolic engineering in construction of the advanced biotechnological producers’ (aud. 329) 11:00 – 11:50 Plenary Lecture-2 11:50 – 12:50 Oral presentations (3)
12:50 – 13:50 LUNCH BREAK
Symposium VIII. 'Studying biology in single-molecule resolution' (aud. 329)
13:50 – 14:50 Oral presentations (3)
Symposium IX. 'Biochemical mechanisms in disease' (aud. 329)
14:50– 15:50 Oral presentations (3)
15:50 – 16:20 COFFEE/TEA BREAK (hall in front of the Assembly Hall, 2nd floor)
16:20 – 17:00 ‘Speed talks’
17:00 – 17:30 AWARDS AND CLOSING CEREMONY
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SCIENTIFIC PROGRAMME
DAY 1. MONDAY, SEPTEMBER 3
Venue: Palladin Institute of Biochemistry of NAS Ukraine, 9 Leontovycha St.
09:00 – 17:00 Registration
15:00 – 16:30 Workshop Dr. Sandor G. Vari ‘Innovative Medicine Does Not Exist Without Knowledge Transfer’ International Research and Innovation in Medicine Program, Cedars - Sinai Medical Center, Los Angeles, USA, [email protected]
Venue: Taras Shevchenko National University of Kyiv, Main Building, Kyiv, 60 Volodymyrska St. (Assembly Hall)
Chairs:Prof. Serhiy Komisarenko, Prof. Andrzej Legocki, Prof. Amnon Horovitz
17:00 – 17:30 OPENING AND GREETINGS
17:30 – 18:20 Plenary lecture-1 Dr. Edward Perello 'Global Biosecurity in the Century' CBO & Director, Desktop Genetics Ltd, Oxford, UK, [email protected]
18:20 – 19:00 WELCOME CONCERT
19:00 – 20:00 GET-TOGETHER PARTY
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DAY 2. TUESDAY, SEPTEMBER 4
Venue: Taras Shevchenko National University of Kyiv, Main Building, 60 Volodymyrska St.
08:30 – 13:30 Registration (aud.201)
SYMPOSIUM I. ‘INTRACELLULAR SIGNALLING’ (aud. 329)
Chair: Prof. Adam Szewczyk Nencki Institute of Experimental Biology, Poland, [email protected], [email protected]
09:00 – 09:30 Key-note lecture-1 Prof. Przemysław Juszczyński 'Immune evasion mechanisms in classical Hodgkin lymphoma: towards new immunotherapies' Institute of Hematology and Transfusion Medicine, Warszawa, Poland, [email protected]
09:30 – 09:50 Yoni Haitin ‘Structural and biophysical characterization of chloride intracellular channels inherent flexibility' The Tel-Aviv University, Tel-Aviv, Israel, [email protected]
09:50 – 10:10 Daria Rotko 'Mitochondrial potassium channels and carbon monoxide signalling' Nencki Institute of Experimental Biology, Warsaw, Poland, [email protected]
10:10 – 10:30 Serhiy Berehovyi ‘New view on development of diabetic polyneuropathy' ESC Institute of Biology and Medicine, Taras Shevchenko National University of Kyiv, Ukraine, [email protected]
10:30 – 11:30 POSTER SESSION – 1 & COFFEE/TEA BREAK (hall in front of the Assembly Hall, 2nd floor)
SYMPOSIUM II. ‘THE BIOCHEMISTRY OF THE CELL’ (aud. 329)
Chair: Prof. Dana Reichmann The Hebrew University of Jerusalem, Jerusalem, Israel, [email protected]
11:30 – 11:50 Oleh Lushchak ‘Trasgenerational effects of late reproduction – an insight from multiomics’ Vasyl Stefanyk Precarpathian National University, Ivano-Frankivsk, Ukraine, [email protected]
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11:50 – 12:10 Efrat Shema ‘Unlocking the Combinatorial Epigenetic Code at a Single-Molecule Level’ The Weizmann Institute of Science, Rehovot, Israel, [email protected]
12:10 – 12:30 Haguy Wolfenson ‘Mechanisms of short- and long-term mechanosensing of matrix rigidity’ Technion-Israel Institute of Technology, Haifa, Israel, [email protected]
SYMPOSIUM III. ‘СELL SIGNALLING IN CANCER’ (aud. 329)
Chair: Prof. Valeriy Filonenko Institute of Molecular Biology and Genetics, Kyiv, Ukraine, [email protected]
12:30 – 12:50 Hagen Hoffmann ‘Coupling enhanced robustness in disordered protein networks’ The Weizmann Institute of Science, Rehovot, Israel, [email protected]
12:50 – 13:10 Inna Gordiienko ‘SLAMF1/CD150-mediated signaling in chronic lymphocytic leukemia B cells’ Ukraine, Kyiv, Ukraine, [email protected]
13:10 – 13:30 Iryna Horak ‘Adaptor protein RUK/CIN85 is a key regulator of epithelial-mesenchymal plasticity of breast cancer cells’ Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, Kyiv, Ukraine, [email protected]
13:30 – 14:30 LUNCH BREAK
SYMPOSIUM IV. ‘LIGAND-RECEPTOR BINDING IN CELL FUNCTIONS AND DRUG DEVELOPMENT’ (aud. 329)
Chair: Prof. Sergiy Kosterin Palladin Institute of Biochemistry, Kyiv, Ukraine, [email protected]
14:30 – 15:00 Key-note lecture-2 Prof. Ivan Gout ‘Protein CoAlation and antioxidant function of Coenzyme A’ University College, London, UK and Institute of Molecular Biology and Genetics, Kyiv, Ukraine, [email protected]
15:00 – 15:20 Kateryna Uspenska ‘The molecular mechanisms of functioning and physiological role of nicotinic acetylcholine receptors in mitochondria’
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Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, Kyiv, Ukraine, [email protected]
15:20 – 15:40 Rostyslav Panchuk ‘Novel anticancer drugs for circumventing multidrug resistance and enhancement of their action through targeted delivery by nanoscale carriers’ Institute of Cell Biology National Academy of Sciences of Ukraine, Lviv, Ukraine, [email protected]
15:40 – 16:00 Joanna Banasiak ‘Medicago ABCG transporter involved in signalling molecules secretion during arbuscularmycorrhiza formation’ Institute of Bioorganic Chemistry, Poznan, Poland, [email protected]
16:00 – 16:30 COFFEE/TEA BREAK
SYMPOSIUM V. ‘FROM CELL TO ORGANISM’ (aud. 329)
Chair: Prof. Shenhav Cohen Technion-Israel Institute of Technology, Haifa, Israel, [email protected]
16:30 – 17:00 Key-note lecture-3 Prof. Amnon Horovitz ‘Chaperonin nano-machines: allostery and function’ The Weizmann Institute of Science Rehovot, Israel, [email protected]
17:00 – 17:30 Key-note lecture-4 Thea Chrysostomou ‘After iGEM’ (iGEM - International Genetically Engineered Machine) The iGEM Foundation, Cambridge, MA, USA, [email protected]
17:30 – 17:50 Moshe Elkabets ‘AXL/AP-1 axes determine sensitivity to PI3Ka therapy in esophageal, and head and neck cancers’ Ben-Gurion University of the Negev, Beer-Sheva, Israel, [email protected]
17:50 – 18:10 Viktoriya Kosach ‘Novel aspects in the of cell motilit y via S6K1’ Institute of molecular biology and genetics, Kyiv, Ukraine, [email protected]
18:10 – 18:30 Gideon Schreiber ‘The evolution of promiscuous interactions’ The Weizmann Institute of Science, Rehovot, Israel, [email protected]
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DAY 3. WEDNESDAY, SEPTEMBER 5
Venue: Taras Shevchenko National University of Kyiv, Main Building, 60 Volodymyrska St.
SYMPOSIUM VI. ‘MOLECULAR BIOLOGY OF BACTERIA AND VIRUSES’ (aud.329) Chair: Prof. Grzegorz Węgrzyn University of Gdańsk, Poland, [email protected]
09:00 – 09:20 Katarzyna Kosznik-Kwaśnicka ‘Comparison of effectiveness of bacteriophages and antibiotics against Salmonella enterica serovars common in poultry’ Institute of Biochemistry and Biophysics Polish Academy of Sciences, Warsaw, Poland, [email protected]
09:20 – 09:40 Andriy Zhuk ‘Identification of endogenous retrovirus Env genes in genome of Gallus gallus and their expression analysis during early embryogenesis’ Institute of molecular biology and genetics, Kyiv, Ukraine, [email protected]
09:40 – 10:00 Aleksandra Dydecka ‘Orf63, orf61 and orf60a as potential regulators of development of lambdoid bacteriophages’ University of Gdańsk, Gdańsk, Poland, [email protected]
10:00 – 11:00 POSTER SESSION – 2 & COFFEE/TEA BREAK (Hall in front of the Assembly hall, 2nd floor)
SYMPOSIUM VII. ‘METABOLIC ENGINEERING IN CONSTRUCTION OF THE ADVANCED BIOTECHNOLOGICAL PRODUCERS’ (aud. 329) Chair: Prof. Andrzej Sybirny University of Rzeszow, Poland-Ukraine, [email protected]@yahoo.com
11:00 – 11:50 Plenary lecture-2 Prof. Nikolaus Rajewsky ‘Single Cell Sequencing in Space and Time’ Berlin Institute for Medical Systems Biology, MDC for Molecular Medicine in the Helmholtz Association, Berlin-Buch, Germany, [email protected]
11:50 – 12:10 Marta Semkiv ‘Glycerol synthesis and bioconversion in conventional versus non-conventional yeasts’ Institute of Cell Biology, Lviv, Ukraine, [email protected]
12:10 – 12:30 Justyna Ruchala
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‘Metabolic engineering of the yeast Ogataea polymorpha for improvement xylose alcoholic fermentation’ Rzeszow University, Rzeszow, Poland, [email protected]
12:30 – 12:50 Dorota Rzechonek ‘From by-product to main product – biosynthesis of citric acid by metabolic engineered yeast Yarrowia lipolytica’ Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland, [email protected]
12:50 – 13:50 LUNCH BREAK
SYMPOSIUM VIII. ‘STUDYING BIOLOGY IN SINGLE-MOLECULE RESOLUTION’ (aud. 329) Chair: Prof. Gideon Schreiber The Weizmann Institute of Science, Rehovot, Israel, [email protected]
13:50 – 14:10 Rina Rosenzweig ‘Substrate Remodeling by Hsp70 Chaperones – What Can We Learn Using NMR’ The Weizmann Institute of Science, Rehovot, Israel, [email protected]
14:10 – 14:30 Norman Metanis ‘Lessons from Selenium Chemistry to Study Protein Science’ The Hebrew University of Jerusalem, Jerusalem, Israel, [email protected]
14:30 – 14:50 Aleksandra Głowacka-Rutkowska ‘The secret life of new polyvalent staphylococcal podovirus phiAGO1.3’ Institute of Biochemistry and Biophysics Polish Academy of Sciences, Warsaw, Poland, [email protected]
SYMPOSIUM IX. ‘BIOCHEMICAL MECHANISMS IN DISEASE’ (aud.329) Chair: Prof. Rostyslav Stoika Institute of Cell Biology, Lviv, Ukraine, [email protected]
14:50 – 15:10 Alona Prysiazhniuk ‘The role of peripheral dopaminergic system in the pathogenesis of inflammatory bowel diseases’ Taras Shevchenko National University of Kyiv, Ukraine, [email protected]
15:10 – 15:30 Bogna Badyra ‘Targeting key signalling factors as a way to control microglial activation and induction of neuroinflammation’ Department of Transplantation, Medical College Jagiellonian University, Krakow, Poland, [email protected]
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15:30 – 15:50 Shai Bel ‘Secretory Autophagy is a Novel Defense Mechanism in the Intestine’ Bar-Ilan University, Ramat Gan, Israel, [email protected]
15:50 – 16:20 COFFE/TEA BREAK
16:20 – 17:00 ‘Speed talks’
17:00 – 17:30 Awards and Closing Ceremony
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POSTER SESSIONS
Venue: Taras Shevchenko National University of Kyiv, Main Building, 60 Volodymyrska St. (Hall in front of the Assembly hall, 2nd floor)
Posters from 1-01 to 1-64 must be exposed on Tuesday, September 4 before the opening of a morning session and removed in the evening of the same day after First day of Conference closing. Posters guided tour (poster session) will take place during the coffee/brake at 10:30 – 11:30.
Posters from 2-01 to 2-64 must be exposed on Wednesday, September 5 before the opening of a morning session and removed after Conference closing. Posters guided tour (poster session) will take place during the coffee/break at 10:00 – 11:00.
Important! The Poster Competition will take place during the Conference. All authors who wish to participate in the Competition kindly asked to pick up sticker ‘COMPETITION’ from the registration desk and put it on their posters.
The members of Evaluation Committee: Prof. Rostyslav Stoika, Institute of Cell Biology, Ukraine Prof. Maryna Skok, Palladin Institute of Biochemistry, Ukraine Prof. Mykola Veliky, Palladin Institute of Biochemistry, Ukraine Prof. Olga Matyshevska, Taras Shevchenko National University of Kyiv, Ukraine Prof. Ganna Tolstanova, Taras Shevchenko National University of Kyiv, Ukraine
Secretary of Evaluation Committee: Volodymyr Chernyshenko, PhD. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine.
The Evaluation Committee will evaluate the scientific level of presented work and quality of presentation. Winners of the Competition selected by the Committee can be invited to make a short oral report (5 min) on the Conference. Please make sure you are ready to make a presentation before signing for the Competition.
The appropriate poster parameters are: width – 594 mm, height - 841 mm (A1, vertical). All authors should expose their posters accordingly to poster numbers that can be found in Programme of the Poster Session below.
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Poster Session I. Biologically active compounds
1-01 RECIPROCAL EFFECT OF CURCUMIN ON CYTOSKELETON OF RPE CELLS STRESSED WITH HYDROGEN PEROXIDE Ağca C.A. Bingol University. Bingol, Turkey, [email protected]
1-02 HEAD-TO-HEAD COMPARISON OF CALIX[4]ARENE BIS-PHOSPHONIC ACID C-145 AND IT’S SULFUR-CONTAINING ANALOGUE AS HAEMOSTASIS EFFECTORS Didkivskyi V.A. Palladin Institute of Biochemistry, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-03 IN VITRO STUDIES ON ANTICANCER AND ANTIVIRAL PROPERTIES OF A HIGH MOLECULAR WEIGHT FRACTION ISOLATED FROM COELOMIC FLUID OF EARTHWORM DENDROBAENA VENETA Czerwonka A. Maria Curie-Sklodowska University. Lublin, Poland, [email protected]
1-04 MOLECULAR MECHANISM OF FACTOR Xa-INHIBITORS INTERACTION Demenko D. Institute of High Technologies, Taras Shevchenko Kyiv National University. Kyiv, Ukraine, [email protected]
1-05 NOVEL 4-THIAZOLIDINONE DERIVATIVES CHANGE THE ACIDIFICATION OF SYNAPTIC VESICLES IN RAT BRAIN NERVE TERMINALS Dudarenko M. V. Palladin Institute of Biochemistry, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-06
APOPTOSIS INDUCTION IN HUMAN LEUKEMIC CELLS WITH C60 FULLERENE LED-MEDIATED PHOTODYNAMIC THERAPY Grebinyk A. Educational and Scientific Center “Institute of Biology and Medicine” Taras Shevchenko National University of Kyiv. Kyiv, Ukraine, [email protected]
1-07 ANTICANCER ACTIVITY OF NEWLY SYNTHESIZED RESVERATROL DERIVATIVES Garbicz D. Institute of Biochemistry and Biophysics, Polish Academy of Sciences. Warsaw, Poland, [email protected]
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1-08 THE CYTOTOXICITY OF CADMIUM IONS SMALL CONCENTRATIONS IN BONE MARROW CELLS DURING PROLONGED CULTIVATION Kharchenko T V.N. Karazin National University. Kharkiv, Ukraine, [email protected]
1-09 GLIA-SPECIFIC REACTION IN THE DIFFERENT BRAIN AREAS OF RATS AFFECTED WITH PITUITRIN AND IZADRIN Kovalchuk Y. P. Oles Honchar Dnipro National University. Dnipro, Ukraine, [email protected]
1-10 IMPACT OF ANTIOXIDANTS SELENOMETHIONINE AND D-PANTETHINE ON FUNCTIONAL STATUS OF GLUTATHIONE SYSTEM IN MULTIDRUG RESISTANT TUMOR CELLS UNDER DOXORUBICIN TREATMENT Kozak Yu. S. IIvan Franko National University of Lviv. Lviv, Ukraine, [email protected]
1-11 CURCUMIN PREVENTS CYTOSKELETON DISREGULATION AND ASTROCYTE REACTIVITY INDUCED WITH LIPOPOLYSACHARIDE Kyrychenko V.V. Oles Honchar Dnipro National University. Dnipro, Ukraine, e-mail: [email protected]
1-12 DIAMIDE-INDUCED MODIFICATIONS OF PROTEINS IN MEMBRANE- CYTOSKELON COMPLEX OF CRYOPRESERVED ERYTHROCYTES Mykhailova O Institute for Problems of Cryobiology and Cryomedicine, NAS of Ukraine. Kharkiv, Ukraine, [email protected]
1-13 THE ACTIVITY OF THE ENZYMES OF THE STONE MOROKO UNDER THE INFLUENCE OF THE HEAVY METALS IONS Marenkov O.N. Oles Honchar Dnipro National University. Dnipro, Ukraine,[email protected]
1-14 DETERMINATION OF THE AMOUNT OF MALONDIALDEHYDE IN THE LIVER OF THE PUMPKINSEED AS A MARKER OF LIPID PEROXIDATION OXIDATION Marenkov O.N. Oles Honchar Dnipro National University. Dnipro, Ukraine,[email protected]
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1-15 INFLUENCE OF PLANT-DERIVED EXTRACTS ONTO CANCER CELLS AND PLATELETS Marunych R.Y. Palladin Institute of Biochemistry, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-16 MODULATING THE INNATE IMMUNE RESPONSE TO INFLUENZA A VIRUS H1N1 (A/FM/1/47) BY COMPLEXES OF OLIGORIBONUCLEOTIDES WITH D-MANNITOL Melnichuk N.S. Institute of Molecular Biology and Genetics, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-17 IDENTIFICATION AND CHARACTERIZATION OF POTENTIAL MOLECULAR DRUG TARGETS OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS USING IN SILICO APPROACHES Pernatii A.Yu. Institute of Molecular Biology and Genetics, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-18 SALT OF HEAVY METALS AS EFFECTORS OF PEPTIDEHYDROLASE FROM DROSOPHILA MELANOGASTER Ryzhko I. L. Odesa I.I. Mechnykov National University. Odesa, Ukraine, [email protected]
1-19 INFLUENCE OF SUPPRESSION SYNTHESIS OF NITRIC OXIDE ON BIOCHEMICAL PARAMETERS OF BLOOD Spirina V.A. Oles Honchar Dnipro National University. Dnipro, Ukraine, [email protected]
1-20 INHIBITION EFFECT OF CALIX[4]ARENES ON PLASMIN ACTIVITY Yatsenko T. Palladin Institute of Biochemistry, NAS of Ukraine. Kyiv, Ukraine, [email protected]
Poster Session II. Biotechnology
1-21 INFLUENCE OF MELANINS OF CLADOSPORIUM CLADOSPORIOIDES ON THERMAL STABILITY OF HUMAN INTERFERON-Β Bulanchuk I.М. Institute of Microbiology and Virology, NAS of Ukraine. Kyiv, Ukraine, [email protected]
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1-22 β-KETOENOLE DYE AS AN AMYLOID-SENSITIVE FLUORESCENT PROBE FOR BACTERIAL BIOFILM INVESTIGATION Chernii S. Institute of Molecular Biology and Genetic, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-23 FLUORESCENT PENTAMETHINE BENZOTHIAZOLE CYANINE DYES FOR SENSING OF SERUM ALBUMINS Chernii S. Institute of Molecular Biology and Genetic, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-24 NANOPARTICLES AFFECT THE EXPRESSION OF IMMUNE-RESPONSE ASSOSIATED GENES IN NORMAL HUMAN ASTROCYTES Tsymbal D.O. Palladin Institute of Biochemistry, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-25 INTERACTION OF POLYVALENT T7-LIKE BACTERIOPHAGES WITH NATURALLY OCCURRING E. COLI STRAINS Faidiuk Yu.V. ESC “Institute of Biology and Medicine”,Taras Shevchenko National University of Kyiv. Kyiv, Ukraine, [email protected]
1-26 DEVELOPING OF NEW MODEL FOR STUDY OF HYPERGLYCEMIA EFFECT UTILIZING CARASSIUS AURATUS STRESS RESPONSES AND DIFFERENT SOURCES OF GLYCANS Gnatyshyna l.l. Ternopil Volodymyr Hnatiuk National Pedagogical University. Ternopil, Ukraine, [email protected]
1-27 FATTY ACID PROFILES in planktoniic and biofilm P. AERUGINOSA cells WITH DIFFERENT LEVEL OF C-DI-GMP Galkin M., Odessa National I.I. Mechnykov University. Odesa, Ukraine, [email protected]
1-28 DETECTION OF MARKERS IN THE FAT-ACID PROFILE OF BACILLUS SUBTILIS ONU551 - DESTRUCTOR OF DISINFECTANTS Gorshkova O. G.
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Odessa National I.I. Mechnykov University. Odesa, Ukraine, [email protected]
1-29 PECULIARITIES OF CHEMICAL COMPOSITION OF PHENOL-OXIDIZING STRAIN CELLS AEROMONAS ICHTHIOSMIA ONU552 Gorshkova O.G. Odessa National I.I. Mechnykov University. Odesa, Ukraine, [email protected]
1-30 COMPUTATIONAL MODELING OF SIRTUIN7 Hałasa M. Medical University of Lublin. Lublin, Poland, [email protected]
1-31 IDENTIFYING NEW PATHOGENIC GENETIC FACTORS OF SEX DEVELOPMENT DISORDERS USING WHOLE-EXOME SEQUENCING Kozyrieva K. ESC “Institute of Biology and Medicine”, Taras Shevchenko Kyiv National University. Kyiv, Ukraine, [email protected]
1-32 ANALYSIS OF APOPTOSIS/NECROSISIS STAGES OF CORD BLOOD NUCLEATED CELLS AFTER CRYOPRESERVATION WITH DMSO AND GLUTATHIONE Makashova O.Ye. Institute for Problems of Cryobiology and Cryomedicine, NAS of Ukraine. Kharkiv, Ukraine, [email protected]
1-33 BACTERIAL DIVERSITY IN SOILS, CONTAMINATED AFTER THE CHORNOBYL ACCIDENT: THE FIRST ANALYSYS ATTEMPT Pareniuk O. National University of Life and Environmental Sciences of Ukraine. Kyiv, Ukraine, [email protected]
1-34 ADAPTIVE LABORATORY EVOLUTION AS A TOOL TO INCREASE THE ABILITY OF MICROORGANISMS FOR BIODEGRADATION OF BIOPLASTICS Urbanek A. K. Wroclaw University of Environmental and Life Sciences. Wrocław, Poland, [email protected]
1-35 PRODUCTION OF IL7-HIS RECOMBINANT PROTEIN for purification of polyclonal antibodies Usenko M.O.
18
Institute of Molecular Biology and Genetics, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-36 NANOBASED ZEARALENONE SENSING SYSTEM FOR HEALTHCARE APPLICATIONS Yarynka D.V. Institute of Molecular Biology and Genetics, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-37 ESTABLISHMENT AND CHARACTERIZATION OF S6K1 ISOFORM-SPECIFIC KNOCKOUT HEK-293 CELLS Zaiets I.V. Institute of Molecular Biology and Genetics, NAS of Ukraine. Kyiv, Ukraine, [email protected]
Poster Session III. Cancer studies
1-38 MOLECULAR CHARACTERISTICS OF AN INTERACTION BETWEEN PROSTATE TUMOR CELLS AND THE HOST ORGANISM Gerashchenko G.V. Institute of Molecular Biology and Genetics, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-39 FIRST STEP TO CHAOS: TUMOR-ASSOCIATED ABNORMALITIES IN MICRORNA EXPRESSION PATTERN CAN AFFECT EPITHELIAL CELL ADHESION, POLARITY AND MITOTIC SPINDLE ORIENTATION Halytskiy V.A. Palladin Institute of Biochemistry, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-40 ANTICANCER PROPERTIES OF MAGNOFLORINE AGAINST CANCER CELLS Jarząb A. Medical University of Lublin. Lublin Poland, [email protected]
1-41 THE ROLE OF THE FBXO11 GENE IN EPITHELIAL-MESENCHYMAL TRANSITION (EMT) Kałafut J. Medical University of Lublin. Lublin Poland, [email protected]
19
1-42 L-CANAVANINE INHIBITS CELL GROWTH UNDER ARGININE DEPLETION BY INDUCING CELL DEATH IN HUMAN GLIOBLASTOMA CELL LINES Karatsai O. Nencki Institute of Experimental Biology PAS. Warsaw, Poland, [email protected]
1-43 GENETIC AND EPIGENETIC CHANGES ON PLASMA CELL-FREE DNA AS MARKERS OF RENAL CELL CARCINOMA Kashparova О. Institute of Molecular Biology and Genetic, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-44 INFLUENCE OF TRANSPLANTATED ALLOGENIC BONE MARROW AND ADIPOSE DERIVED MESENCHYMAL STROMAL CELLLS ON THE BIOCHEMICAL PARAMETERS OF C57Bl/6 MOUSES BLOOD Kladnytska L.V. National University of Life and Environmental Sciences of Ukraine. Kyiv, Ukraine, [email protected]
1-45 HOW TO CATCH THE CHEATING CANCER CELLS? PD-1/PD-L1 IMMUNE CHECKPOINT BLOCKERS IN ACTION: SMALL-MOLECULES, MACROCYCLIC PEPTIDES AND ANTIBODIES Kocik J. Jagiellonian University in Krakow. Krakow, Poland, [email protected]
1-46 THE EFFECTS OF MDM2-p53 ANTAGONIST RG7388 ON THE PROLIFERATION OF HUMAN OSTEOSARCOMA CELLS Machula M. Jagiellonian University in Krakow. Krakow, Poland, [email protected]
1-47 HWAY AND IL2-STAT5 PATHWAYS ARE INACTIVATED IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS Matvieieva A.S. R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine. Kyiv, Ukraine, [email protected]
1-48 GENETIC MODEL OF ESR1 Y537S MUTATION IN BREAST CANCER MCF7 CELLS Miziak P. Medical University of Lublin. Lublin, Poland, [email protected]
20
1-49 MANNOSE-CONTAINING GLYCOTOPES OF LEUKOCYTES IN NEURO- ONCOLOGICAL DISEASE Netronina O.V. State Establishment "Dnipropetrovsk Medical Academy of Health Ministry of Ukraine". Dnipro, Ukraine, [email protected]
1-50 HISTONE DEACETYLASE INHIBITORS MODULATE EXPRESSION OF EPITHELIAL- MESENCHYMAL TRANSITION (EMT) PROTEIN MARKERS IN BREAST CANCER CELL LINES Okoń E. Medical University of Lublin. Lublin, Poland, [email protected]
1-51 ALKBH overexpression in neck and head cancer as new field for anticancer therapy Pilżys T. Institute of Biochemistry and Biophysics, PAS. Warsaw, Poland, [email protected]
1-52 ASSESMENT OF INTERACTIONS BETWEEN HISTONE DEACETYLASE INHIBITORS AND CISPLATIN IN BREAST CANCER CELLS WITH ALTERED NOTCH 1 ACTIVITY Wawruszak A. Medical University of Lublin. Lublin, Poland, [email protected]
1-53 ASSESSMENT OF THE CLINICOPATHOLOGICAL RELEVANCE OF MESOTHELIN LEVEL IN PLASMA, PERITONEAL FLUID AND TUMOR TISSUE OF EPITHELIAL OVARIAN CANCER PATIENTS Wawruszak A. Medical University of Lublin. Lublin, Poland, [email protected]
Poster session IV. Clinical studies
1-54 USP1 PROTEIN COLOCALIZES WITH BCR-ABL ONCOPROTEIN IN K562 CELLS AND ACTS AS POTENTIAL TARGET FOR CML THERAPY Antonenko S.V. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
1-55 CORRELATION BETWEEN METABOLIC MARKERS AND BONE MINERAL DENSITY IN DIAGNOSIS OF OSTEOPOROSIS Brazaluk O.Z.
21
State Establishment "Dnipropetrovsk Medical Academy of Health Ministry of Ukraine", Dnipro, Ukraine, [email protected]
1-56 15q11.2-q13 ALTERATIONS IN PATIENTS WITH PRADER-WILLI AND ANGELMAN SYNDROMES. Chernushyn S.Yu. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
1-57 STUDY OF ADENOSINE DEAMINASE IN ERYTHROCYTES OF PATIENTS WITH BURN SHOCK Fedorova A.A. Donetsk National Medical University, Kramatorsk, Ukraine, [email protected]
1-58 THE ADRB2 GENE A46G AND C79G POLYMORPHISMS IN THE BRONCHIAL ASTHMA CHILDREN FROM UKRAINE Gulkovskyi R. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
1-59 THE NEW SMOOTH MUSCLE CELL CONTRACTION AGENT - CALIX[4]ARENE C-956 Veklich T.O. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine, [email protected]
1-60 EXPRESION OF BRAF, YWHAS, EGF AND AURORA KINASES’ GENES IN URINE SEDIMENTS FROM PATIENTS WITH PROSTATE CANCER Mankovska O.S. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
1-61 DGGE-BASED STRATEGY FOR THE SCREENING OF EEF1A2 GENE MUTATIONS Perebyinis V.M. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
22
1-62 AUTOPHAGY INUCTION AS A STRATEGY FOR TREATMENT OF VARIOUS DISEASES CAUSED BY ACCUMULATION OF PATHOGENIC MACROMOLECULES Wegrzyn G. University of Gdansk, Gdansk, Poland, [email protected]
1-63 MOLECULAR-BIOLOGICAL AND CHEMOTAXONOMIC INDICATIONS OF SUPERFOODS PROPERTIES AS INNOVATIVE COMPONENTS OF PREVENTIVE MEDICINE Kotliiar Ye.A. Odesa National Academy of Food Technologies, Odesa, Ukraine, [email protected]
1-64 MOLECULAR-GENETIC DIAGNOSTICS OF BACTERIAL MICROBIOTA FOR PREDICTING ALIMENTARY IMPACT ON THE HUMAN ORGANISM Zykova N.S. Odesa National Academy of Food Technologies, Odesa, Ukraine, [email protected]
Poster Session V. Medicinal Biochemistry
2-01 THE EFFECTS MELANIN ON THE LEVEL OF PRO- AND ANTI-INFLAMMATORY CYTOKINES IN SERUM OF RATS WITH PROGESTERONE-INDUCED OBESITY Aleksandrov A.V Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, [email protected]
2-02 THE REACTION OF THE MICROGLIA DUE TO ACUTE WATER-IMMOBILIZATION STRESS AND UNDER INFLUENCE OF α-KETOGLUTARATE Muraviova D. Oles Honchar Dnipro National University, Dnipro, Ukraine [email protected]
2-03 DEVELOPMENT OF OXIDATIVE STRESS IN RATS BRAIN IN CONDITIONS OF MELATONIN DEFICIENCY Che K. Oles Honchar Dnipro National University, Dnipro, Ukraine, [email protected]
2-04 CANINЕ ЕRYTHROCYTЕ MЕMBRANЕ PЕRMЕABILITY: QUANTITIVЕ ЕFFЕCTS OF INITIAL CRЕANATION ON FRAGILITY Dеnysova O. Kharkiv Statе Vеtеrinary Acadеmy, Mala Danylivka, Ukrainе, dе[email protected]
23
2-05 STRESS INDUCED CHANGES OF THE GLIAL FIBRILARY ACIDIC PROTEIN LEVEL IN THE RAT`S BRAIN AND 2-OXOGLUTARATE IMPACT Dovban O.O. Oles Honchar Dnipro National University, Dnipro, Ukraine, [email protected]
2-06 INTEGRIN α2β1 IS INVOLVED IN REGULATION OF COLLAGEN DEPOSITION IN CARDIAC FIBROBLAST CULTURED ON BOTH SOFT OR HARD GELLS Gałdyszyńska M. Medical University of Lodz, Lodz, Poland, [email protected]
2-07 MELATONIN EFFECT ON THE HEPATIC HYDROGEN SULFIDE SYSTEM OF RATS UNDER CONDITIONS OF EXPERIMENTAL NEPHROPATHY Kolianyak I.O. Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine, [email protected]
2-08 THE INFLUENCE OF 14 DAYS INTRODUCTION OF MELATONIN ON THE CYSTATHIONIN-β-SYNTHASE AND CYSTATHIONINE-γ-LYASE ACTIVITY OF HYDROGEN SULFIDE SYNTHESIS IN THE LIVER OF ALLOXAN DIABETIC RATS Luhinich N.M. Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine, [email protected]
2-09 CHANGE OF CYTOSKELETON ACTIN ISOFORMS SPECTRUM IN AGING SKIN FIBROBLASTS AT MECHANICAL DEFORMATION Grytsenko M. V. N. Karazin Kharkiv National University, Kharkiv, Ukraine, [email protected]
2-10 AGING IMPACT ON THE MITOCHONDRIAL PROOXIDANT/ANTIOXIDANT BALANCE IN THE GERBIL`S LIVER Koloda M.I. Oles Honchar Dnipro National University, Dnipro, Ukraine, [email protected]
2-11 BIOCHEMICAL STATUS OF LIVER UNDER WATER-IMMOBILIZATIONSTRESS AND α-KETOGLUTARATE IMPACT Kudryashova M. Oles Honchar Dnipro National University, Dnipro, Ukraine, [email protected]
24
2-12 THE POTENTIAL PROTECTIVE EFFECT OF OLIGORIBONUCLEOTIDES-D- MANNITOL COMPLEXES AGAINST THIOACETAMIDE-INDUCED LIVER FIBROSIS Marchyshak T.V. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-13 INFLUENCE OF VITAMIN E ON ASTROCYTES IN BRAIN OF OLD DIABETIC RATS. Murdasov E. Oles Honchar Dnipro National University, Dnipro, Ukraine, [email protected]
2-14 SOME BIOCHEMICAL PARAMETERS OF RAT HEPATOCYTES UNDER INCUBATION WITH ORTHOVANADATE NANOPARTICLES Pavliy A. K. V. N. Karazin Kharkiv National University, Kharkiv, Ukraine, [email protected]
2-15 ANTI-INFLAMMATORY EFFECT OF LIPOSOMAL CURCUMIN IN THE NEOCORTEX AND HIPPOCAMPUS OF RAT BRAIN WITH ALZHEIMER’S DISEASE MODEL Sokolik V. V. State Institution “Institute of Neurology, Psychiatry and Narcology of the National Academy of Medical Sciences of Ukraine”, Kharkiv, Ukraine, [email protected]
2-16 ABOUT SOME MECHANISMS OF DERMATOTROPIC ACTION OF MELANIN Taburets O.V. ESC “Institute of Biology and Medicine”, Taras Shevchenko Kyiv National University, Kyiv, Ukraine, [email protected]
2-17 HEMOGLOBIN SYSTEM AND ENZYMATIC ACTIVITY OF ERYTHROCYTES IN CHOLELITHIASIS Voronkova Yu.S. Oles Honchar Dnipro National University, Dnipro, Ukraine, [email protected]
2-18 EFFECT OF PROBIOTIC ON PARAMETERS OF GLUTATHIONE SYSTEM AND LIPID OXIDATION IN SERUM OF RATS WITH MONOIODOACETATE-INDUCED OSTEOARTHRITIS Vovk A.A. ESC “Institute of Biology and Medicine”, Taras Shevchenko Kyiv National University, Kyiv, Ukraine, e-mail: [email protected]
25
2-19 THE FUNCTIONING OF DUODENUM MUCOSA SEROTONIN SYSTEM UNDER CONSUMPTION OF KIDNEY BEAN (PHASEOLUS VULGARIS) PODS EXTRACT IN THE OBESE MODEL OF RATS Yurchenko A.V. ESC “Institute of Biology and Medicine”, Taras Shevchenko Kyiv National University, Kyiv, Ukraine, [email protected]
Poster Session VI. Metabolism regulation and pathology
2-20 BIOCHEMICAL PROPERTIES OF NO-SYNTHASE ACTIVITY IN UTERUS SMOOTH MUSCLE MITOCHONDRIA Bohach T.V. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-21 EFFECT OF 3 DAYS GLUTATHIONE INTRODUCTION ON ENERGY METABOLISM IN THE LIVER MITOCHONDRIA OF RATS WITH NEPHROPATHY Ferenchuk Ye.O. Higher State Educational Establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine, [email protected]
2-22
DIMINISHING OF BISPHENOL A EFFECTS BY NANOPARTICLES TiO2 IN THE SENTINEL ORGANISM DOES NOT RELATED TO ENDOCRINE DISRUPTION Khoma V.V. Ternopil V. Hnatiuk National Pedagogical University, Ternopil, Ukraine, [email protected],
2-23 CHANGES IN THE INFLAMMATION STATE OF WHITE ADIPOSE TISSUE IN RATS WITH DIET-INDUCED OBESITY AT THE DIFFERENT TIMES OF MELATONIN ADMINISTRATION Kalmukova O. O. ESC “Institute of Biology and Medicine”, Taras Shevchenko Kyiv National University, Kyiv, Ukraine, [email protected]
2-24 SUSCEPTIBILITY OF GLUTATHIONE SYSTEM TO MELATONIN INJECTIONS IN BRAIN OF ALLOXAN DIABETIC RATS Kushnir O.Yu. Higher State Educational Establishment of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine, [email protected]
26
2-25 ACTIVITY OF PYRUVATE KINASE IN THE MUSCLE TISSUE OF ALLOXAN DIABETIC RATS INJECTED BY MELATONIN IN DOSE 5 MG/KG Kushnir O.Yu. Higher State Educational Establishment of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine, [email protected]
2-26
THE ROLE OF VITAMIN D3 IN MODULATION OF GLUCOCORTICOID-INDUCED CHANGES IN ANGIOGENESIS/OSTEOBLASTOGENESIS/OSTEOCLASTOGENESIS COUPLING Lisakovska O.O. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-27 HYDROGEN SULFIDE METABOLISM MODULATORS INFLUENCE THIOL/DISULPHIDE STATUS IN STREPTOZOTOCIN-INDUCED DIABETIC RAT’S HEART Palamarchuk I.V. Vinnytsia National Pirogov Memorial Medical University, Vinnytsia, Ukraine, [email protected]
2-28 ACTIVE TRANSPORT OF Cа2+ IN THE PLASMA MEMBRANE OF ROOTS UNDER SALT STRESS CONDITIONS AND ACTION OF THE PREPARATION METHYURE Rudnytska M.V. Kholodny Institute of Botany, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-29 PEROXIREDOXIN 2 INTERACTION NETWORK REVEALS ENRICHMENT IN GENES LINKED TO INFLAMMATION-RELATED PATHOLOGIES Ruzin Yu. M. School of Biology, V.N. Karazin Kharkiv National University, Kharkiv, Ukraine, [email protected]
2-30 THE EFFECT OF N-STEAROYLETHANOLAMINE ON CHOLESTEROL CONTENT OF ADIPOCYTES IN DIFFERENT AGE RATS WITH OBESITY-INDUCED INSULIN RESISTANCE Tkachenko O.S. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
27
Poster Session VII. Molecular Biology
2.31 OF THE PHYSIOLOGICAL AND GENETIC DIFFERENCES BETWEEN THE WHITE COLLARED FLYCATCHER AND PIED FLYCATCHER OF THE GENUS FICEDULA Drahulian M.V National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine, [email protected]
2-32 E. COLI ALKB AND ITS HUMAN HOMOLOG ALKBH3 DIOXYGENASES EFFECTIVELY REPAIRED ACROLEIN ADDUCTS TO ADENINE Dylewska M. Institute of Biochemistry and Biophysics, Polish Academy of Science, Warsaw, Poland, [email protected]
2-33 COMPUTATIONAL ANALYSIS OF EPS15 3’UTR IN DIFFERENT SPECIES Frankiv N. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-34 MUTATIONS IN EPHA1 GENE ASSOCIATED WITH INTELLECTUAL DISABILITY AND ALZHEIMER'S DISEASE Gulkovskyi R. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-35 MICRORNA- AND RBP-BASED REGULATION OF GENES INVOLVED IN THE REMODELING OF ACTIN CYTOSKELETON Hubiernatorova A. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-36 SPERM MEDIATED GENE TRANSFER (SMGT) IN DUCK (ANAS PLATYRHYNCHOS) Konoval O.M. National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine, [email protected]
2-37 HYPOXIC REGULATION OF ENDOPLASMIC RETICULUM STRESS RESPONSIVE GENE EXPRESSIONS IN IRE1 KNOCKDOWN GLIOMA CELLS
28
Luzina O. Y. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-38 PREDICTING MODEL OF REGULATORY RELATIONSHIPS BETWEEN LONG NON- CODING RNAS ANRIL/XIST AND DISEASE-ASSOCIATED MICRORNAS N. Malyshok Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukrain, [email protected]
2-39 CONSTRUCTION, CLONING AND EXPRESSION OF THE FVIII GENE WITHOUT B DOMAIN IN CHO-DHFR CELLS Mazurkiewicz-Pisarek A. Institute of Biotechnology and Antibiotics, Warsaw, Poland, [email protected]
2-40 EXPRESSION OF THE FVIII GENE WITHOUT B DOMAIN IN E.COLI BACTERIAL EXPRESSION SYSTEM Mazurkiewicz-Pisarek A. Institute of Biotechnology and Antibiotics, Warsaw, Poland, [email protected]
2-41 CONSTRUCTION, CLONING AND EXPRESSION OF THE ANTI-CD22 MONOCLONAL ANTIBODY IN THE E. COLI BACTERIAL EXPRESSION SYSTEM Mikiewicz D. Institute of Biotechnology and Antibiotics, Warsaw, Poland, [email protected]
2-42 OBTAINING THE LIRAGLUTIDE PEPTIDE IN THE UNIVERSAL EXPRESSION SYSTEM IN ESCHERICHIA COLI BACTERIAL CELLS Wójtowicz-Krawiec A. Institute of Biotechnology and Antibiotics, Warsaw, Poland, [email protected]
2-43 INFLUENCE OF OLIGORIBONUCLEOTIDES ON THERMAL STABILITY OF METHYLTRANSFERASE ECORI Nikolaiev R.O. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-44 IRE1 KNOCKDOWN LEADS TO SUPPRESSION OF GLIOBLASTOMA GROWTH Ratushna O.O.
29
Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-45 GENE EXPRESSION IN HUMAN PLACENTA: ON THE WAY FROM FOLATE- RELATED ONE CARBON SUBSYSTEM TO TRANSCRIPTOME. Ralchenko S. Institute of molecular biology and genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-46 METABOLIC REPROGRAMMING OF MITOCHONDRIA IN IRE1 knockdown U87 GLIOMA CELLS Riabovol O.O. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-47 CHIRALITY DURING PROTEIN BIOSYNTHESIS: THE ROLE OF HYDROXYL GROUPS OF TRNATYR IN D-TYR AMINOACYLATION AND PROOFREADING REACTIONS AGAINST ITS INVOLVEMENT IN TRANSLATION Rybak M. Yu. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-48 THE MOLECULAR CONSTRUCTOR PROGRAM BUILDS STRUCTURAL TEMPLATES OF PROTEINS ACCORDING TO THEIR DETERMINING NUCLEOTIDE SEQUENCES Sokolik V. V. State Institution “Institute of Neurology, Psychiatry and Narcology of the National Academy of Medical Sciences of Ukraine”, Kharkiv, Ukraine, [email protected]
2-49 HSP90α EXPRESSION IN THE SMALL INTESTINE AND HSP70 BLOOD SERUM LEVELS IN RATS WITH CARRAGEENAN-INDUCED ENTERITIS Tkachenko A.S. Kharkiv National Medical University, Kharkiv, Ukraine, [email protected]
2-50 SITE-DIRECTED MUTAGENESIS OF TRYPTOPHAN RESIDUES IN THE STRUCTURE OF TYROSYL-tRNA SYNTHETASE BOS TAURUS Tsuvariev O.Yu. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
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Poster Session VIII. Proteomics
2-51 BRADYKININ B2 RECEPTOR AND DOPAMINE D2 RECEPTOR COOPERATIVELY REGULATE LEPTIN- AND INSULIN-DEPENDENT SIGNALING PATHWAYS IN HUMAN NEURON-LIKE CELLS Guevara-Lora I. Jagiellonian University in Krakow, Krakow, Poland, [email protected]
2-52 EFFECT OF HB-EGF INTERACTION WITH HEPARAN SULFATE PROTEOGLYCANS ON GROWTH FACTOR INTERNALIZATION TO CYTOPLASM Krynina O.I Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-53 ICD-SENSITIVITY OF IRON (II) CLATHROCHELATES TO GLOBULAR PROTEINS Kuperman M. Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-54 N-ALKYL FUNCTIONALIZED STYRYL CYANINES FOR FLUORESCENT DETECTION OF NUCLEIC ACIDS Kuperman M. Institute of Molecular Biology and Genetics, NAS of Ukriane, Kyiv, Ukraine, [email protected]
2-55 TRANSLOCATION DOMAIN OF DIPHTHERIA TOXIN (DT) PARTICIPATES IN THE REALIZATION OF ANTITUMOR EFFECT OF NON-TOXIC RECOMBINANT DT DERIVATIVES Manoilov K.Yu. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-56 ITSN1 IS A POTENTIAL PARTNER OF MICROTUBULE-ASSOCIATED PROTEIN TAU Martsishevska I., ESC “Institute of Biology and Medicine”, Taras Shevchenko Kyiv National University, Kyiv, Ukraine, [email protected]
2-57 FTO DIOXYGENASE STRUCTURE AND ITS INTERACTORS - BIOPHYSICAL STUDIES Marcinkowski M.
31
Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland, [email protected]
2-58 IDENTIFICATION OF ISOZYMES OF MALATE DEHYDROGENASE ABLE TO BIND OF THIAMINE Mezhenska O.A. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-59 DETECTION AND CHARACTERIZATION OF THE INTERACTION BETWEEN RNA- BINDING PROTEIN SAM68 AND SCAFFOLD PROTEIN ITSN1 Pankivskyi S.V. Institute of Molecular Biology and Genetics, NAS of Ukraine. Kyiv, Ukraine, [email protected]
2-60 PLATELETS IN COORDINATION OF COAGULATION AND FIBRINOLYSIS Revka O.V. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-61 CHANGES IN MATRIX METALLOPROTEINASE-9 SECRETION, PHAGOCYTES ACTIVATION, MATURATION AND APOPTOSIS, IN VITRO, IN RESPONSE TO MYCOBACTERIUM TUBERCULOSIS COMPLEX ANTIGENS MPT63 AND MPT83 Siromolot A.A. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-62 SEARCH OF NEW PLATELET-BINDING SITES WITHIN αС-REGIONS OF FIBRINOGEN Stohnii Y.M. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-63 THE ROLE OF FIBRINOGEN BβN-DOMAIN IN THE MIGRATION OF CANCER CELLS Tsap P. Yu. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv, Ukraine, [email protected]
2-64 OXIDATIVE-MODIFIED LIPOPROTEINS AS BIOMARKERS OF CARDIOVASCULAR DAMAGE IN PATIENTS WITH ARTERIAL HYPERTENSION Kuchmenko O.B. National Scientific Centre “Strazhesko Institute of Cardiology”, NAMS of Ukraine, Kyiv, Ukraine, [email protected]
32
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