DOCSLIB.ORG

Mushrooms & Marine 2012

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

M & M Mushrooms and Marine Howard A. Greller Introduction • Mushrooms are the fruiting body of a fungus • More than 40,000 species worldwide • 5000 species in U.S., < 2% poisonous • 79% poison < 6 years old • Raw >> cooked • Allergy and anaphylaxis more common than poisoning Mushroom Anatomy and identification General properties of mushrooms. Not everyone has the “cup” (pileus) (lamella) (annulus) cup (volva) (stape) (mycelial threads) Mushroom ID • Books • Location • Size, color, shape • Spore print • Spore ID • Mycologist Melzer’s reagent (mycologist prefers) - 20 mL H2O, 1.5 g K iodide, 0.5 g iodine, 20 g chloral hydrate - Defines presence of amatoxin = dark blue Meixner reaction (reliability = doubtful) - http://namyco.org/ Several drops 10-12 N HCl on newspaper to amatoxin-containing spore - blue reaction Tricksy mushrooms yeeesssss. precious . Cortinarius speciosissimus. Nephrotoxic (non-US). Wound up with a renal transplant (from his daughter). His wife and pssst. Nicholas . the Lord he was dining eat these. they’re yummy. with are still on dialysis. Famous mushroom quote number one There are old mushroom hunters, and there are bold mushroom hunters. But there are no old, bold mushroom hunters. Mushroom Taxonomy Classification Famous mushroom quote number two Falling in love is like eating (poisonous) mushrooms. You never know if it is the real thing until it’s too late. Cyclopeptides Group I Amanita phalloides Amanita verosa Modern series have a lower case fatality rate Amanita species - cyclopeptides - A. phalloides (death cap), A. virosa (death angel) - 95% mushroom related fatalities, 50% case fatality - One mushroom enough to kill an adult Galerina autumnalis Lepiota helveola Galerina & Lepiota species - cyclopeptides - G. autumnalis, G. marginata, G. venenata - L. helveola, L. josserandi, Lbrunneoincarnata Cyclopeptides Amatoxins (cyclic octapeptides) - α-amanitin - heat stabile - poorly absorbed, enterohepatic recirculation - interferes with RNA polymerase II, protein translation - sodium-taurocholate co-transporter polypeptide - centrilobular hepatic necrosis with intact architecture Cyclopeptides Phallotoxins (cyclic heptapeptides) - Phalloidin - limited absorption - interrupts actin polymerization - impairs cell membrane function Cyclopeptides Virotoxins (cyclic heptapeptides) - Virotoxin - ? human toxicity Toxicity - cyclopeptides Phase I - not earlier than 6 hours, lasts up to 24 hours - initial cholera-like diarrhea, then nausea/vomiting Phase II - “quiescent” phase (no n&v) - hepatotoxicity Phase III - hepatic, renal, pancreatic - death 2-3 days after ingestion thioctic acid is a co-enzyme in TCA cycle, free radical scavenger Therapeutics - cyclopeptides PCN displaces amanitin from albumin, Early blocks uptake, binds circulating - volume resuscitation amatoxins, prevents amanitin from - ? MDAC - ? hemodialysis / hemoperfusion binding to RNA polymerase Late(r) Silymarin block amatnitin uptake - thioctic (α-lipoic) acid NAC is good for what ails the liver - penicillin G (1.6 million U/kg/day) Cimetidine potentially inhibits - silymarin (silibinin) from milk thistle metabolism - n-acetylcysteine - cimetidine Bioartificial Liver (“bridge” to recovery or T/P) Therapeutics Liver Transplant (EARLY > late) •Bioartificial liver •Liver transplant •Early >> late Gyrometrin Group II gyromitra esculenta morchella esculenta Gyromitra species - gyromitrin - G. esculenta, G. californica, G. brunnea, G. infula - found in spring under conifers - often confused for the edible morel Gyromitrin - N-methyl-N-formyl hydrazone - hydrolyzed to monomethylhydrazine - heat sensitive (although fumes have ? toxicity) ➜➜➜ gyromitrin monomethylhydrazine Toxicity - gyromitrin - asymptomatic for at least 6 hours - initial GI symptoms - seizures GAD - glutamic acid decarboxylase, PPK - pyridoxal phosphokinase hydrazines ! - inactivate pyridoxal 5’ phosphate ! - inhibit pyridoxal phosphokinase ! - complex with and lead to increased urinary excretion of pyridoxine GAD glutamic acid GABA pyridoxal 5’ phosphate PPK hydrazines pyridoxine Therapeutics - gyromitrin Early - ? GI decontamination Seizures - benzodiazepines - pyridoxine (vit B6) - 70 mg/kg up to 5 grams - anesthetic barbiturates pyridoxine Muscarine Group III clitocybe clavipes inocybe geophylia Clitocybe species - muscarine - C. dealbata (‘the sweater’),C. illudens Inocybe species - muscarine - I. Iacera, I. geophylla Muscarine Quarternary ammonium compound - Does not cross BBB (no CNS) - Not nicotinic - Not susceptible to ACHase hydrolysis acetylcholine muscarine When you think of rain, always bring a “sweater” Toxicity - muscarine - Rapid onset of toxicity (within 30 minutes) - SLUDGE - NO nicotinic findings (i.e. mydriasis, tachycardia, weak) Therapeutics - muscarine - Atropine (infrequently required) - ACLS doses to start - titrate until relief of symptoms, dry secretions - NO oximes (i.e. 2-PAM) Coprine Group IV Coprinus atramentarius Coprinus comatus Coprinus - coprine - C. comatus, C. atramentarius - Undergo “autodigestion” - inky caps - pleasant tasting, edible mushrooms - problematic with ethanol (disulfiram like reaction) Coprine Toxicity comes from primary metabolite - 1-aminocyclopropanol - ethanol present or ingested within 24-48 hours - usually okay if done together (delayed toxicity) ➜➜➜ coprine 1-aminocyclopropanol Toxicity - coprine - rapid onset of toxicity (within 1 hour) - inhibits aldehyde dehydrogenase - disulfiram reaction - flushing - nausea & vomiting - tachycardia - headache disulfiram Therapeutics - coprine - intravenous fluids - antiemetics - analgesics - time (for ethanol to be metabolized) + = Ibotenic acid / Muscimol Group V Amanita muscaria Amanita gemmata Modern series have a lower case fatality rate Amanita muscaria - ibotenic acid / muscimol - A. muscaria (fly agaric), A. pantherina, A. gemmata - popular children’s books and games - Babar, Super Mario Bros. NOT MUSCARINIC, NOT ANTI MUSCARINIC Ibotenic acid / muscimol Ibotenic acid - structurally similar to glutamic acid Muscimol - decarboxylated metabolite of ibotenic acid - similar to GABA ibotenic acid muscimol glutamic acid GABA Toxicity - ibotenic acid / musicmol - rapid onset (0.5 - 2 hours), resolves 6-12 hours - mild GI upset - ibotenic acid stimulates glutamic acid receptors - hallucinosis, excitation - musicmol acts as a GABA agonist - somnolence, ataxia - seizures rare (GABAB agonism) - adults manifest more GABA-ergic symptoms - pediatrics excitatory transmission predominates Therapeutics - ibotenic acid / muscimol - supportive care - benzodiazepines for seizures, excitation - no role for flumazenil for sedation Psilocybin / Psilocin Group VI Psilocybe cubensis Psilocybe cyanescens Gymnopilus spectabilis, Psathyrella foenisecii Psilocybe species - psilocybin / psilocin - P. cyanescens, P. cubensis, G. spectabilis, P. foenisecii - “magic mushrooms” - Native american religious customs, drug culture - when handled, develop blue bruises Psilocybin / psilocin Structural similarity to serotonin - interact with serotonin receptors, no adrenergic effects - rapid onset, medium duration (1 - 6 hours) - psilocybin is rapidly hydrolyzed to psilocin psilocybin serotonin psilocin illusion hallucination pallinopsia synesthesia Toxicity - psilocybin / psilocin - Early GI effects (0.5 - 1 hour) - illusions - synesthesias - “heightened perceptions” - true hallucinations are rare and dose dependent - autonomic response to altered perceptions Therapeutics - psilocybin / psilocin Primary supportive care - benzodiazepines - avoid neuroleptics - risk hallucinogen persistent perceptive disorder (HPPD) Little Brown Mushrooms Group VII russula emetica Chlorophyllum molybdites Little Brown Mushrooms (LBM) - GI toxins - Boletes, Lactarius sp., Omphalotus sp., Tricholoma sp. - Lycoperdon sp., Agaricus, Entoloma, Chlorophyllum sp. - Largest group of mushrooms - Often mistaken for edible or hallucinogenic LBM - GI toxins Heterogenous toxins - terpenes and lactones - unknown specific mechanism or toxin - direct irritant? allergic phenomenon? Toxicity - LBM - Early GI effects (0.5 - 3 hours) - rapid resolution without significant consequence - Paxillus Syndrome (rare) - P. involutus, Clitocybe claviceps, Boletus luridus - involutin? (diphenylcyclopenteneone) - immune-mediated hemolytic anemia, renal failure - repeated long term exposure Therapeutics - LBM Primary supportive care - intravenous hydration - antiemetics - antidiarrheals Prevention Orelline / Orellanine Group VIII cortinarius speciosissimus cortinarius archeri Cortinarius sp. - orelline / orellanine - C. orellanus, C. speciosissimus, C.rainierensis (NA) - Only recent recognition of toxicity Oreline / Orellanine Bipyridyl agents - similar to paraquat/diquat - heat stable - direct irritant? allergic phenomenon? orellanine paraquat Toxicity - orelline / orellanine - asymptomatic for 24 - 26 hours - headache, chills, anorexia, n/v (flu-like) - oliguric renal failure - ATN - similar prognosis to other causes of ATN Therapeutics - LBM Primary supportive care - intravenous hydration - hemodialysis - transplantation reported, but very rare Prevention Allenic norleucine Group IX amanita smithiana tricholoma magnivelare Amanita smithiana - allenic norleucine - mistaken for tricholoma magnivelare (matsutake) - Pacific N.W. US Allenic norleucine 2-amino-4,5-hexadienoic acid - limited mechanistic information - may be the compound Toxicity - allenic norleucine Phase I - early GI distress (0.5 - 12 hours) - malaise, diaphoresis, dizzy Phase II - 4-6 days after ingestion - acute renal
Recommended publications
  • Electrophysiologic Evidence for Increased Endogenous Gabaergic but Not Glycinergic Inhibitory Tone in the Rat Spinal Nerve Ligation Model of Neuropathy Vesa K

    Electrophysiologic Evidence for Increased Endogenous Gabaergic but Not Glycinergic Inhibitory Tone in the Rat Spinal Nerve Ligation Model of Neuropathy Vesa K

    Anesthesiology 2001; 94:333–9 © 2001 American Society of Anesthesiologists, Inc. Lippincott Williams & Wilkins, Inc. Electrophysiologic Evidence for Increased Endogenous GABAergic but Not Glycinergic Inhibitory Tone in the Rat Spinal Nerve Ligation Model of Neuropathy Vesa K. Kontinen, M.D., Ph.D.,* Louise C. Stanfa, Ph.D.,† Amlan Basu,‡ Anthony H. Dickenson, Ph.D.§ Background: Changes in the inhibitory activity mediated by There is evidence that both GABA and glycinergic inter- ␥-aminobutyric acid (GABA) and glycine, acting at spinal GABA A neurons are preferentially associated with the control of receptors and strychnine-sensitive glycine receptors, are of in- 6–9 terest in the development of neuropathic pain. There is ana- low-threshold afferent input to the spinal cord. Con- Downloaded from http://pubs.asahq.org/anesthesiology/article-pdf/94/2/333/402482/0000542-200102000-00024.pdf by guest on 29 September 2021 tomic evidence for changes in these transmitter systems after sistent with this, intrathecal administration of the 10 nerve injuries, and blocking either GABAA or glycine receptors GABAA-receptor antagonist bicuculline or the glycine- has been shown to produce allodynia-like behavior in awake receptor antagonist strychnine10,11 produces segmen- normal animals. tally localized tactile allodynia-like behavior in conscious Methods: In this study, the possible changes in GABAergic and glycinergic inhibitory activity in the spinal nerve ligation rats and increased responses to mechanical stimulation 12 model of neuropathic pain were studied by comparing the in anesthetized cats. Intrathecal strychnine has also effects of the GABAA-receptor antagonist bicuculline and the been shown to produce in anesthetized rats reflex re- glycine-receptor antagonist strychnine in neuropathic rats to sponses similar to those produced by nociceptive stim- their effects in sham-operated and nonoperated control rats.
  • Molecular Phylogenetic Studies in the Genus Amanita

    Molecular Phylogenetic Studies in the Genus Amanita

    1170 Molecular phylogenetic studies in the genus Amanita I5ichael Weiß, Zhu-Liang Yang, and Franz Oberwinkler Abstracl A group of 49 Amanita species that had been thoroughly examined morphologically and amtomically was analyzed by DNA sequence compadson to estimate natural groups and phylogenetic rclationships within the genus. Nuclear DNA sequences coding for a part of the ribosomal large subunit were determined and evaluated using neighbor-joining with bootstrap analysis, parsimony analysis, conditional clustering, and maximum likelihood methods, Sections Amanita, Caesarea, Vaginatae, Validae, Phalloideae, and Amidella were substantially confirmed as monophyletic groups, while the monophyly of section Lepidell.t remained unclear. Branching topologies between and within sections could also pafiially be derived. Stbgenera Amanita an'd Lepidella were not supported. The Mappae group was included in section Validae. Grouping hypotheses obtained by DNA analyses are discussed in relation to the distribution of morphological and anatomical chamcters in the studied species. Key words: fungi, basidiomycetes phylogeny, Agarrcales, Amanita systematics, large subunit rDNA, 28S. R6sum6 : A partir d'un groupe de 49 esp,ces d'Amanita prdalablement examinees morphologiquement et anatomiquement, les auteurs ont utilisd la comparaison des s€quences d'ADN pour ddfinir les groupes naturels et les relations phylog6ndtiques de ce genre. Les sdquences de I'ADN nucl6aire codant pour une partie de la grande sous-unit6 ribosomale ont 6t6 ddterminEes et €valu6es en utilisant l'analyse par liaison en lacet avec le voisin (neighbor-joining with bootstrap), l'analyse en parcimonie, le rcgroupement conditionnel et les m€thodes de ressemblance maximale. Les rdsultats confirment substantiellement les sections Afiarira, Caesarea, Uaqinatae, Ualidae, Phalloideae et Amidella, comme groupes monophyldtiques, alors que la monophylie de la section Lepidella demerxe obscure.
  • Unnamed Document

    Unnamed Document

    Mutations M287L and Q266I in the Glycine Receptor ␣1 Subunit Change Sensitivity to Volatile Anesthetics in Oocytes and Neurons, but Not the Minimal Alveolar Concentration in Knockin Mice Cecilia M. Borghese, Ph.D.,* Wei Xiong, Ph.D.,† S. Irene Oh, B.S.,‡ Angel Ho, B.S.,§ S. John Mihic, Ph.D.,ʈ Li Zhang, M.D.,# David M. Lovinger, Ph.D.,** Gregg E. Homanics, Ph.D.,†† Edmond I. Eger 2nd, M.D.,‡‡ R. Adron Harris, Ph.D.§§ ABSTRACT What We Already Know about This Topic • Inhibitory spinal glycine receptor function is enhanced by vol- Background: Volatile anesthetics (VAs) alter the function of atile anesthetics, making this a leading candidate for their key central nervous system proteins but it is not clear which, immobilizing effect if any, of these targets mediates the immobility produced by • Point mutations in the ␣1 subunit of glycine receptors have been identified that increase or decrease receptor potentiation VAs in the face of noxious stimulation. A leading candidate is by volatile anesthetics the glycine receptor, a ligand-gated ion channel important for spinal physiology. VAs variously enhance such function, and blockade of spinal glycine receptors with strychnine af- fects the minimal alveolar concentration (an anesthetic What This Article Tells Us That Is New EC50) in proportion to the degree of enhancement. • Mice harboring specific mutations in their glycine receptors Methods: We produced single amino acid mutations into that increased or decreased potentiation by volatile anesthetic in vitro did not have significantly altered changes in anesthetic the glycine receptor ␣1 subunit that increased (M287L, third potency in vivo transmembrane region) or decreased (Q266I, second trans- • These findings indicate that this glycine receptor does not me- membrane region) sensitivity to isoflurane in recombinant diate anesthetic immobility, and that other targets must be receptors, and introduced such receptors into mice.
  • Perth Urban Bushland Fungi Field Book

    Perth Urban Bushland Fungi Field Book

    Perth Urban Bushland Fungi Field Book (A Self-Managed Format) Author Neale L. Bougher Format and Electronic Design John R. Weaver Publisher: Perth Urban Bushland Fungi 3rd Edition, 2007 Foundation 1st Edition May 2005 2nd Edition November 2005 3rd Edition February 2007 This book is Copyright. Approval is granted to reproduce this Field Book in whole or in part, for personal and educational purposes only. The Field Book may be downloaded from the Perth Urban Bushland Fungi web site at: http://www.fungiperth.org.au/fieldbook/cat_index.html With the exception of its use for personal and/or educational purposes, electronic storage of data or images from the printed or web site versions of this book and retrieval or transmission in any form from such storage is not permitted. Written permission is required prior to any potential commercial applications or non- personal reproduction or distribution. Enquiries should be made to Perth Urban Bushland Fungi, Western Australian Herbarium, Department of Environment and Conservation, Locked Bag 104, Bentley Delivery Centre, Western Australia 6983. Copyright © text: Neale L. Bougher Copyright © photographs: Neale L. Bougher (unless otherwise stated). Copyright © electronic & printed layout & design: John R. Weaver This book may be cited as: Bougher N.L. (2006). Perth Urban Bushland Fungi Field Book. Perth Urban Bushland Fungi, Perth Western Australia. (Online), from: http://www.fungiperth.org.au/fieldbook/cat_index.html (2 February 2007). © Perth Urban Bushland Fungi - Field Book / Last updated 2/02/2007 Page ii Acknowledgements PUBF activities are the result of a core team comprising Neale Bougher (Mycologist), John Weaver (Formatting and Electronic Presentation and Data Management), Roz Hart (Community Education Officer) and Sarah de Bueger (Project Officer, 2006) with past assistance from Jac Keelan-Wake (Administrative Support 2004-2005).
  • Treatment of Amatoxin Poisoning: 20-Year Retrospective Analysis

    Treatment of Amatoxin Poisoning: 20-Year Retrospective Analysis

    MARCEL DEKKER, INC. • 270 MADISON AVENUE • NEW YORK, NY 10016 ©2002 Marcel Dekker, Inc. All rights reserved. This material may not be used or reproduced in any form without the express written permission of Marcel Dekker, Inc. Journal of Toxicology CLINICAL TOXICOLOGY Vol. 40, No. 6, pp. 715–757, 2002 ARTICLE Treatment of Amatoxin Poisoning: 20-Year Retrospective Analysis Franc¸oise Enjalbert,* Sylvie Rapior, Janine Nouguier-Soule´, Sophie Guillon, Noe¨l Amouroux, and Claudine Cabot Laboratoire de Botanique, Phytochimie et Mycologie, Faculte´ de Pharmacie, Universite´ Montpellier 1, Montpellier Cedex 5, France; Laboratoire de Physique Mole´culaire et Structurale, UMR-CNRS 5094, Faculte´ de Pharmacie, 15 avenue Charles Flahault, BP 14 491, 34093 Montpellier Cedex 5, France; and Centre Anti-Poisons, Hoˆpital Purpan, Place du Docteur Baylac, 31059 Toulouse Cedex, France ABSTRACT Background: Amatoxin poisoning is a medical emergency characterized by a long incubation time lag, gastrointestinal and hepatotoxic phases, coma, and death. This mushroom intoxication is ascribed to 35 amatoxin-containing species belonging to three genera: Amanita, Galerina, and Lepiota. The major amatoxins, the a-, b-, and g-amanitins, are bicyclic octapeptide derivatives that damage the liver and kidney via irreversible binding to RNA polymerase II. Methods: The mycology and clinical syndrome of amatoxin poisoning are reviewed. Clinical data from 2108 hospitalized amatoxin poisoning exposures as reported in the medical literature from North America and Europe over the last 20 years were compiled. Preliminary medical care, supportive measures, specific treatments used singly or in combination, and liver transplantation were characterized. Specific treatments consisted of detoxication procedures (e.g., toxin removal from bile and urine, and extra- corporeal purification) and administration of drugs.
  • Field Guide to Common Macrofungi in Eastern Forests and Their Ecosystem Functions

    Field Guide to Common Macrofungi in Eastern Forests and Their Ecosystem Functions

    United States Department of Field Guide to Agriculture Common Macrofungi Forest Service in Eastern Forests Northern Research Station and Their Ecosystem General Technical Report NRS-79 Functions Michael E. Ostry Neil A. Anderson Joseph G. O’Brien Cover Photos Front: Morel, Morchella esculenta. Photo by Neil A. Anderson, University of Minnesota. Back: Bear’s Head Tooth, Hericium coralloides. Photo by Michael E. Ostry, U.S. Forest Service. The Authors MICHAEL E. OSTRY, research plant pathologist, U.S. Forest Service, Northern Research Station, St. Paul, MN NEIL A. ANDERSON, professor emeritus, University of Minnesota, Department of Plant Pathology, St. Paul, MN JOSEPH G. O’BRIEN, plant pathologist, U.S. Forest Service, Forest Health Protection, St. Paul, MN Manuscript received for publication 23 April 2010 Published by: For additional copies: U.S. FOREST SERVICE U.S. Forest Service 11 CAMPUS BLVD SUITE 200 Publications Distribution NEWTOWN SQUARE PA 19073 359 Main Road Delaware, OH 43015-8640 April 2011 Fax: (740)368-0152 Visit our homepage at: http://www.nrs.fs.fed.us/ CONTENTS Introduction: About this Guide 1 Mushroom Basics 2 Aspen-Birch Ecosystem Mycorrhizal On the ground associated with tree roots Fly Agaric Amanita muscaria 8 Destroying Angel Amanita virosa, A. verna, A. bisporigera 9 The Omnipresent Laccaria Laccaria bicolor 10 Aspen Bolete Leccinum aurantiacum, L. insigne 11 Birch Bolete Leccinum scabrum 12 Saprophytic Litter and Wood Decay On wood Oyster Mushroom Pleurotus populinus (P. ostreatus) 13 Artist’s Conk Ganoderma applanatum
  • Environmental Properties of Chemicals Volume 2

    Environmental Properties of Chemicals Volume 2

    1 t ENVIRONMENTAL 1 PROTECTION Esa Nikunen . Riitta Leinonen Birgit Kemiläinen • Arto Kultamaa Environmental properties of chemicals Volume 2 1 O O O O O O O O OO O OOOOOO Ol OIOOO FINNISH ENVIRONMENT INSTITUTE • EDITA Esa Nikunen e Riitta Leinonen Birgit Kemiläinen • Arto Kultamaa Environmental properties of chemicals Volume 2 HELSINKI 1000 OlO 00000001 00000000000000000 Th/s is a second revfsed version of Environmental Properties of Chemica/s, published by VAPK-Pub/ishing and Ministry of Environment, Environmental Protection Department as Research Report 91, 1990. The pubiication is also available as a CD ROM version: EnviChem 2.0, a PC database runniny under Windows operating systems. ISBN 951-7-2967-2 (publisher) ISBN 952-7 1-0670-0 (co-publisher) ISSN 1238-8602 Layout: Pikseri Julkaisupalvelut Cover illustration: Jussi Hirvi Edita Ltd. Helsinki 2000 Environmental properties of chemicals Volume 2 _____ _____________________________________________________ Contents . VOLUME ONE 1 Contents of the report 2 Environmental properties of chemicals 3 Abbreviations and explanations 7 3.1 Ways of exposure 7 3.2 Exposed species 7 3.3 Fffects________________________________ 7 3.4 Length of exposure 7 3.5 Odour thresholds 8 3.6 Toxicity endpoints 9 3.7 Other abbreviations 9 4 Listofexposedspecies 10 4.1 Mammais 10 4.2 Plants 13 4.3 Birds 14 4.4 Insects 17 4.5 Fishes 1$ 4.6 Mollusca 22 4.7 Crustaceans 23 4.8 Algae 24 4.9 Others 25 5 References 27 Index 1 List of chemicals in alphabetical order - 169 Index II List of chemicals in CAS-number order
  • Fungi of North East Victoria Online

    Fungi of North East Victoria Online

    Agarics Agarics Agarics Agarics Fungi of North East Victoria An Identication and Conservation Guide North East Victoria encompasses an area of almost 20,000 km2, bounded by the Murray River to the north and east, the Great Dividing Range to the south and Fungi the Warby Ranges to the west. From box ironbark woodlands and heathy dry forests, open plains and wetlands, alpine herb elds, montane grasslands and of North East Victoria tall ash forests, to your local park or backyard, fungi are found throughout the region. Every fungus species contributes to the functioning, health and An Identification and Conservation Guide resilience of these ecosystems. Identifying Fungi This guide represents 96 species from hundreds, possibly thousands that grow in the diverse habitats of North East Victoria. It includes some of the more conspicuous and distinctive species that can be recognised in the eld, using features visible to the Agaricus xanthodermus* Armillaria luteobubalina* Coprinellus disseminatus Cortinarius austroalbidus Cortinarius sublargus Galerina patagonica gp* Hypholoma fasciculare Lepista nuda* Mycena albidofusca Mycena nargan* Protostropharia semiglobata Russula clelandii gp. yellow stainer Australian honey fungus fairy bonnet Australian white webcap funeral bell sulphur tuft blewit* white-crowned mycena Nargan’s bonnet dung roundhead naked eye or with a x10 magnier. LAMELLAE M LAMELLAE M ■ LAMELLAE S ■ LAMELLAE S, P ■ LAMELLAE S ■ LAMELLAE M ■ ■ LAMELLAE S ■ LAMELLAE S ■ LAMELLAE S ■ LAMELLAE S ■ LAMELLAE S ■ LAMELLAE S ■ When identifying a fungus, try and nd specimens of the same species at dierent growth stages, so you can observe the developmental changes that can occur. Also note the variation in colour and shape that can result from exposure to varying weather conditions.
  • The Reading Naturalist

    The Reading Naturalist

    The Reading Naturalist No. 53 Published by the Reading and District Natural History Society 2001 Price to Non Members £2.50 T H E R E A D I N G N A T U R A L I S T No 53 for the year 2000 The Journal of the Reading and District Natural History Society President Mr Rod d’Ayala Honorary General Secretary Mrs Catherine Butcher Honorary Editor Dr Malcolm Storey Editorial Sub-committee The Editor, Dr Alan Brickstock, Mrs Linda Carter, Mr Hugh H. Carter Miss June M. V. Housden, Mr David G. Notton Honorary Recorders Botany: Mrs Linda Carter, Fungi: Dr Alan Brickstock Entomology: Mr David G. Notton Invertebates other than insects: Mr Hugh H. Carter Vertebrates: Mr Hugh H. Carter CONTENTS Obituary 1 Members’ Observations 1 Excursions Meryl Beek 2 Wednesday Afternoon Walks Alan Brickstock 5 Meetings (1999-2000) Catherine Butcher 6 The Fishlock Prize 7 Membership Norman Hall 8 Presidential address: Some Mycological Ramblings Alan Brickstock 9 Natural History Services provided at the Museum of Reading David G. Notton 13 A Mutant Foxglove Malcolm Storey 16 Sehirus dubius (or should that be dubious!) Chris Raper 17 Hartslock – a Local Success Story Chris Raper 17 Recorders’ Reports Malcolm Storey 19 “RDB” and “N” status – The Jargon Explained Rod d’Ayala 19 Recorder’s Report for Botany 2000 Linda Carter 20 The New Berkshire Flora Malcolm Storey 23 Recorder’s Report for Mycology 2000 Alan Brickstock 24 Recorder’s Report for Entomology 2000 David G. Notton 27 Recorder’s Report for Invertebrates other than insects 2000 Hugh H.
  • Toxicological and Pharmacological Profile of Amanita Muscaria (L.) Lam

    Toxicological and Pharmacological Profile of Amanita Muscaria (L.) Lam

    Pharmacia 67(4): 317–323 DOI 10.3897/pharmacia.67.e56112 Review Article Toxicological and pharmacological profile of Amanita muscaria (L.) Lam. – a new rising opportunity for biomedicine Maria Voynova1, Aleksandar Shkondrov2, Magdalena Kondeva-Burdina1, Ilina Krasteva2 1 Laboratory of Drug metabolism and drug toxicity, Department “Pharmacology, Pharmacotherapy and Toxicology”, Faculty of Pharmacy, Medical University of Sofia, Bulgaria 2 Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, Bulgaria Corresponding author: Magdalena Kondeva-Burdina ([email protected]) Received 2 July 2020 ♦ Accepted 19 August 2020 ♦ Published 26 November 2020 Citation: Voynova M, Shkondrov A, Kondeva-Burdina M, Krasteva I (2020) Toxicological and pharmacological profile of Amanita muscaria (L.) Lam. – a new rising opportunity for biomedicine. Pharmacia 67(4): 317–323. https://doi.org/10.3897/pharmacia.67. e56112 Abstract Amanita muscaria, commonly known as fly agaric, is a basidiomycete. Its main psychoactive constituents are ibotenic acid and mus- cimol, both involved in ‘pantherina-muscaria’ poisoning syndrome. The rising pharmacological and toxicological interest based on lots of contradictive opinions concerning the use of Amanita muscaria extracts’ neuroprotective role against some neurodegenerative diseases such as Parkinson’s and Alzheimer’s, its potent role in the treatment of cerebral ischaemia and other socially significant health conditions gave the basis for this review. Facts about Amanita muscaria’s morphology, chemical content, toxicological and pharmacological characteristics and usage from ancient times to present-day’s opportunities in modern medicine are presented. Keywords Amanita muscaria, muscimol, ibotenic acid Introduction rica, the genus had an ancestral origin in the Siberian-Be- ringian region in the Tertiary period (Geml et al.
  • Pt Reyes Species As of 12-1-2017 Abortiporus Biennis Agaricus

    Pt Reyes Species As of 12-1-2017 Abortiporus Biennis Agaricus

    Pt Reyes Species as of 12-1-2017 Abortiporus biennis Agaricus augustus Agaricus bernardii Agaricus californicus Agaricus campestris Agaricus cupreobrunneus Agaricus diminutivus Agaricus hondensis Agaricus lilaceps Agaricus praeclaresquamosus Agaricus rutilescens Agaricus silvicola Agaricus subrutilescens Agaricus xanthodermus Agrocybe pediades Agrocybe praecox Alboleptonia sericella Aleuria aurantia Alnicola sp. Amanita aprica Amanita augusta Amanita breckonii Amanita calyptratoides Amanita constricta Amanita gemmata Amanita gemmata var. exannulata Amanita calyptraderma Amanita calyptraderma (white form) Amanita magniverrucata Amanita muscaria Amanita novinupta Amanita ocreata Amanita pachycolea Amanita pantherina Amanita phalloides Amanita porphyria Amanita protecta Amanita velosa Amanita smithiana Amaurodon sp. nova Amphinema byssoides gr. Annulohypoxylon thouarsianum Anthrocobia melaloma Antrodia heteromorpha Aphanobasidium pseudotsugae Armillaria gallica Armillaria mellea Armillaria nabsnona Arrhenia epichysium Pt Reyes Species as of 12-1-2017 Arrhenia retiruga Ascobolus sp. Ascocoryne sarcoides Astraeus hygrometricus Auricularia auricula Auriscalpium vulgare Baeospora myosura Balsamia cf. magnata Bisporella citrina Bjerkandera adusta Boidinia propinqua Bolbitius vitellinus Suillellus (Boletus) amygdalinus Rubroboleus (Boletus) eastwoodiae Boletus edulis Boletus fibrillosus Botryobasidium longisporum Botryobasidium sp. Botryobasidium vagum Bovista dermoxantha Bovista pila Bovista plumbea Bulgaria inquinans Byssocorticium californicum
  • Catalogue No. 121 – Sale, Special Offers and Recent Acquisitions

    Catalogue No. 121 – Sale, Special Offers and Recent Acquisitions

    C. Arden, Bookseller Darren Bloodworth The Nursery, Forest Road, Hay-on-Wye, HR3 5DT, U.K. Tel: +44 (0) 1497-820471 Email: [email protected] Web: www.ardenbooks.co.uk Catalogue No. 121 – Sale, Special Offers and Recent Acquisitions Sale items : Botany 1 - 112 Entomology 113 - 140 Fine, Illustrated & Antiquarian 141 - 151 Gardening 152 - 207 General 208 - 254 Natural History & Zoology 255 - 266 New Naturalist s 267 - 302 Ornithology 303 - 346 Special offers : Botany 347 - 404 and recent Entomology 405 - 440 acquisitions Fine, Illustrated & Antiquarian 441 - 458 Gardening 459 - 512 Natural History & Zoology 513 - 562 New Naturalists 563 - 611 Ornithology 612 - 688 The stock in the Sale part of this catalogue (items 1 to 346) is an attempt to clear the remains of stock from the year’s previous catalogues. Book prices have already been reduced in many cases and further reductions are available to those who wish to take a risk that their chosen books will be available 10 or even 20 days after receiving this catalogue. Books will be dispatched once orders are complete – this may take up to three weeks if you order books at 50% off. How the Sale works First 10 days of sale…….All books available at prices shown in the catalogue After 10 days……………..If books are still available, we reduce their prices by 25% After 20 days……………..If books are still available, we reduce their prices by 50% We have also included over three hundred Special offers and recent acquisitions at the end of the catalogue (items 347 to 688). These Special offers and recent acquisitions are available at the prices indicated and are not part of the Sale terms.