Neurotransmitters in the Sexuality of the Pedophile and the Pedophile Killer

Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020 5

Special article NEUROTRANSMITTERS IN THE SEXUALITY OF THE PEDOPHILE AND THE PEDOPHILE KILLER

Received: 18.01.2020 Accepted: 8.02.2020

1*Vasile NIȚESCU, 2**Doina RAMBA N, 3*** Valentin NIȚESCU

1.*Medical Centre for Obstetrics-Gynaecology and Sexology; 2 **“Colentina” Clinical Hospital-Internal Medicine Clinic 3 ***Department of Surgery, Clinical Hospital “Dr.I. Cantacuzino”

Abstract The minor and major sexual deviations of the pedophile and the pedophile killer cause sexual satisfaction outside the normal human sexual intercourse. Any form of sexual assault on the child attests, however, to the existence of brain damage, that has been classified in various clinical forms of disease.

Keywords: neurotransmitters, pedophiles, criminals, sexual deviations, brain damage

* Correspondence: 1*Professor Nițescu Vasile, MD,PhD, E-mail [email protected], phone +40723151804, 2** Ramba N Doina, MD, PhD: E-mail: [email protected], 3***Nițescu Valetin, MD E-mail: [email protected], Phone:+40740953351. 6 Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020

pattern according to the genetic sex of the person, modularized under the auspices of endogenous and exogenous peculiarities, of Typically, minor sexual deviations in interneuronal connections and, respectively, adults may coexist with normal sexual inter- of the transmission of bioelectric impulse course, in which some authors (H.Brainerd, through neurotransmitters. S.Margen, M.Chatton) argue that their prac- The hypothalamus, part of the diencepha- tice does not fit into a pathological form. In lus, is located in the antero-inferior region authors view, only minor sexual deviations of the brain (Fig.1), being linked to the ce- are acceptable, which increase the excitabi- rebral cortex, brainstem and spinal cord by lity of the two adult partners, but do not cau- tracts and fibers, respectively by hypophysis se any harm (physical, neuro-psychic, moral) vascular system located in the pituitary stalk. to practitioners. In adenohypophysis and in the portal hypo- In the desire to obtain as much pleasure physeal vascular system are stored neuro- as possible, at a time of increased erotic ex- transmitters, such as dopamine, essential in citability, some adults accept the practice of sexual intercourse, produced by neurons of minor sexual deviations. On the other hand, the tubero-infundibular system, acetylcholi- sexual perversions imposed by the pedophi- ne, serotonin and histamine, with inhibitory le on the child, regardless of gender and age, or excitatory effect. are determined by the state of excitation with Through the portal hypophyseal vascular the pedophile’s patological behavior, accor- system, the hypothalamus, through gonadoli- ding to brain pathology. In this context, the berin and, partly, dopamine, that is synthesi- pedophile is not only a forensic case, throu- zed mainly in the arcuate nucleus and in the gh sexual offense, but one can consider that black substance, controls the gonadotropic paedophilia is a neuropsychiatric case to be function of adenohypophysis. At the pituitary treated medically, as such. level, they determine the synthesis and elimination of circulating pituitary gonadotropins, Minor sexual deviations and sexual per- which will act on the gonads, inducing the versions present in adults, in both sexes, have synthesis and elimination of the secretion of a much higher frequency in men. Normally, sex hormones, thus the hypothalamus being they are never performed on the child due directly involved in the determinism of sexu- to the neocortex, which plays an important al motivation. role in behavior control. Inter-human sexual relationship, through the mechanism of se- The secretion of LH-RF and FSH-RF is lective inhibition of pathological factors such determined by the predominant secretion of as aggression, serious forms of physical and one of the two hypothalamic centers located neuropsychic abuse or the killing of the child, in the dorso-medial nucleus, the tonic center restores normal sexual behavior. Quantitati- and the preoptic nucleus with the phasic cen- ve and qualitative modulation is done at ter. The secretion of these hormones acts on the level of the structures of the hypothala- the two centers through the short feedback mus (2,3,4), establishing a sexual behavior mechanism, the phasic center being the trigger Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020 7

Fig. 1 The link of the hypothalamus with basal ganglia (image from the Treaty of Clinical Sexology) center. In turn, gonadal hormones induce and receptors in the cytoplasm or nucleus. The develop sexual motivation, individual poten- activated Hormone-Receptor complex then cy, libido and erection, respectively orgasm, binds to a DNA (promoter) sequence, activa- essential elements of sexual intercourse. Go- ting or inhibiting the transcription of specific nadal and adrenal steroids bind to the intra- genes and the RNA-messenger (mRNA-m) cellular protein receptors, and not to receptors formation.The attack and violence against the on the cellular membrane, thus connecting to child, or even its death after copulation, by

Fig. 2 Thalamus – intermediate station between the cerebral cortex and the lower levels of the Central Nervous System (image from the Treaty of Clinical Sexology) 8 Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020

involving neuropsychic and physical factors cerebral cortex is reached. specific to the pedophile and the killer, causes The posterior hypothalamus is connec- altered ejaculation and orgasm. ted to the sympathetic vegetative nervous The hypothalamus has direct connections system, whose center is located at the level with the thalamus (anterior nuclei) through of thoracic spinal cord T11-T12 and lumbar hypothalamic-thalamic fibers, and from here, spinal cord L2-L3, acting as an erection inhi- through thalamo-cortical fibers (Fig.2), the bitor (Fig.3).

Fig.3 Inhibition of penile erection (image from the Treaty of Clinical Sexology)

The antero-lateral hypothalamus is con- of the penis, the pedophile cannot perform nected to the parasympathetic center in the pathological sexual act on the child. This si- sacral spinal cord S2-S4, in order to determi- tuation proves, however, that the pathology ne the erection, essential to the abusive act of of the pedophile is neuro-psychic, as a direct the pedophile (Fig.4). Without the erection . determination of erection, so the treatment should be adapted to it .

Fig.4 Triggering of penile erection (image from the Treated Clinical Sexology)

The hypothalamus is linked to the retina, In the case of the pedophile, it determines derived from the brain (Fig. 5), through reti- the neuro-psychological pathology, the devi- no-hypothalamic fibers of the optic chiasm. ant sexual behavior, which is manifested by The erotic images are retained and stored in acts of physical and neuro-psychic violence, the brain, where they are interpreted and eva- until the murder, after which the criminal se- luated normally or incorrectly, according to xually assaults the child. the structure of the person's brain. Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020 9

Fig. 5.The optic nerve- image from Treaty of Clinical Sexology

The visual analyzer is the first, which by optional homosexuality. correct appreciation, determines whether or The pedophile claims that the sexual re- not the erogenous sensation in humans. lationship with a child is “a normal one”, as Normally, the erection of the penis long as the minor victim accepts it, ignoring is never triggered at the sight of a child, but the fact that, at birth, the newborn’s brain can occur pathologically, in the case of a dis- weighs about 350 grams and until it obtains torted information of the brain, on the data normal weight and brain functions, the child received by the analyzers. possesses insufficient and limited neuro- The reaction of the penile erection, that functionality. has cerebral determinism, at the sight of the In this context, the pedophile can easily 3-5 year old child, is a conclusive proof of carry out sexual abuse of children, by phy- the brain pathology of the pedophile, but also sical and mental coercion, or by threat and attests to the fact that sexuality is not reduced corruption for participation in imposed to an instinctive elementary component. abnormal sexual acts. In the course of these Criminality is defined as committing a cri- abnormal sexual acts, the pedophile, accor- me in a certain place and at a certain time. In ding to some neuropsychiatrists and forensic general, the criminal act is determined by a opinions, is aware of the aberrant impulse, reason or by several motivations. The expla- but, through his pathology, he cannot resist nations of the pedophile’s sexual deviations the impulse to sexually assault and to subject and perversions on the child are aberrant and the child to unimaginable torments (8), di- in accordance with his brain pathology, that rectly influencing the discernment, character of the homo/hetero- or bisexual killer with and conduct of the minor victims. 10 Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020

The severity of paedophilic acts is given some authors (W. Beck), a social taboo. Chil- by the child corruption and early determina- dren, especially girls, are usually victims of tion of vaginal and oral sexual relations with known persons (5). the child, involving physical and mental vio- During pubertal and post-pubertal perio- lence, carried out by the abuser through rape, ds, hormonal changes induce a minor eman- sexual abuse, threat, acts that will not be for- cipation behavior; an example in this regard gotten for the rest of the victims lives. is the provocative dress of the girl, which The 10-12 years old child, being picked induces the criminal a state of excitement, up by a pedophile and subjected to fellatio finally transposed by subsequent dramatic or to masturbation, will force, at the time of consequences - rape and, possibly, trafficking his return to the scholar environment, the yo- of the person in question, murder and necro- unger colleagues to perform the same erotic philia (in necropedophilia the sexual arousal maneuvers that he is determined by the performed on the The severity of paedophilic acts corpse of the child). pedophile. is given by the child corruption and The child targeted Sometimes the early determination of sexual rela- by the pedophile is pedophile does not tions with the child, involving phy- attracted and taken to realize the trauma sical and mental violence, carried distant, dark places, caused to the child, out by the abuser through rape, where he is sexually that is to victims fa- sexual abuse, threat, acts that will assaulted, violently mily or society. In not be forgotten for the rest of the and savagely, subjec- this regard, we men- victims lives. ting him to terrible tion the case of the torments, difficult to pedophile who raped an 11-year-old girl, lea- imagine, the child being physically and men- ving her pregnant; she later became a mother, tally mutilated for life. and her child, the result of rape, was, in turn, The child is brought by the offender to a raped by the same pedophile, thus by his bi- hotel or even to the pedophile’s home, where ological father. After the aggression suffered, he or she offers alcohol or drugs and is even- the child could not recover until after a treat- tually assaulted prior to the sexual act, a con- ment period of three weeks, respectively “he text in which the child is further reduced in could coherently speak a few words” (8). All control of his own behavior. this also proves that the pedophile has a real obsession with the act, unable to control his The immature brain of the minor victim abnormal impulses. confuses sexuality with the affection, becoming dependent on the aggressor, who, when The pedophile knows that he has deviant he becomes the master of the situation, beco- behavior, but at the same time, he “loves” mes a physically and mentally violent man, adrenaline behind the violent acts performed. seriously injuring the child, who will oscilla- In general, sexual abuse of children is te between pleasure, guilt and fear of being not reported, being considered, according to discovered his abnormal acts performed. Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020 11

The pedophile may have family or chil- its injuries at the molecular level, with very dren who are sexually assaulted by him, pro- precise anatomical topography. ving the real existence of behavioral changes. Aggressive pedophilia is often different For example, the child abused by his or her from compulsive sadism (6). own parent moves away from it because of threats, blackmail, violence, becoming a victim of continuous abuse. The significant impact is observed in the child between the ages of 3-4 years, when the Neurotransmitters and brain has the greatest development and re- pathophysiology of pedophilia ceptivity, and the anal pain determined to the minor abused by a peno-rectal act by his own pedophile father is not easily forgotten, nor The role of neurotransmitters is to modu- the terrible moments lived. Mature women late and transmit nerve information to speci- do not matter to the pedophile, but only the fic receptors at the level of inter-neuronal and child has great value (8). neuro-tissue synapses, triggering action po- The pedophile is attracted to the purity of tentials. In the absence of a neurotransmitter, the child he wants as a sexual partner, which the nerve influx does not propagate, so in the underlines that the etiology of the pedophile’s present case, there is no modulation reaction behavioral pathology is complex, not being of the basal or instinctive components of the persons concerned. The information trans- determined by a single neurotransmitter. mitted, but not being modulated, will cause The severity of the pedophile act is deter- the aggression and attack reaction to be a spe- mined not only by the early sexual intercour- cific one to the pedophile, which, thus, can se (vaginal, anal, oral), but also by the physi- even lead to the murder of the minor victim, cal and mental violence, with the contracting possibly followed by a necrophilic sexual act of serious diseases (9), which will shorten Exogenous and endogenous sensory sti- their life, through the pathology developed muli, normal and pathological, respectively over time. imaginative, determine the sexual behavior The pedophile criminal is responsible be- of the person according to his biological po- fore the law for the kidnapping, torture, rape tential and psychosocial environment. and murder of the child, while satisfying the The information of the neuronal cell re- sexual desires, harming the victim’s family ceptors is transformed into bioelectrical im- and society, through the criminal acts com- pulses, being conducted, after processing, at mitted. the cerebral level, respectively in the external The abnormal acts of the pedophile, re- granular layer and in that of the pyramidal spectively of the necrophilic pedophile, have cells, transmitting the information to the cor- been framed by authors in diseases such as tical and subcortical areas. dementia, schizophrenia, oligophrenia, the The bioelectrical impulse is received and pathology of the brain being determined by 12 Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020

transformed, along its path from axon to den- the values of the serum sex hormones, throu- drite, through neurotransmitters, chimneys gh a negative feedback mechanism. located in astrocyte receptors, which provide Normally, many of the very large number energy to neurons, regulating synaptogenesis. of neurotransmitters and neuromodulators Eliminated at the level of the inter-neuro- are involved in mediating behavioral, basal nal synapse, the neurotransmitters thus ensu- or instinctive reactions, respectively in deter- re the transmission of nerve influx, triggering mining the normal behavior of individuals in the action potential, each neurosecretory pro- the family and in society, in which activity duct having a well-defined role (7). is controlled by the perfected central nervous From the physiological point of view, the system. same substance produced by the neuron can The lack or impairment of the neurotrans- act as a neurotransmitter, if released at the mitters involved in the behavioral reactions, synapse, respectively as a neurohormone, if therefore, determines the neuropsychological released in circulation or as a neuromodula- pathology in the pedophile and in the crimi- tor, cyber-paracrine effect (7). nal. Neurotransmitters at axo-dendritic or axo- The limbic system plays an important somatic synapses are excitatory or inhibito- role in the abnormal behavioral reactions. ry, respectively, depolarizing or hyperpola- This determines the normal sexual behavi- rizing the postsynaptic membrane, causing or, heterosexual, through the mechanism of the emergence of an excitatory or inhibitory selective inhibition of the endogenous, ge- postsynaptic potential, triggering or not ac- netic and psychological factors, of agitation, ting potential (7). aggression, timidity, emotionality, etc. by the The information is processed by the cor- presence of the neurotransmitter (2,3). The tical neurosynaptic circuits by processing in limbic system quantitatively and qualitati- layers II-III, after which the cerebral cortex vely modulates the activity of the hypotha- receives the information from the level of the lamus structures and establishes sexual be- cerebral and subcortical layer IV. havior according to the genetic sex and the The data analyzed and transformed into endogenous and exogenous particularities of visual, tactile, olfactory, auditory or gusta- the individual. Bilateral lesions of the limbic tory sensations, corresponding to the type of system underlie progressive dementia and arousal received, will provide the appropriate Korsakoff syndrome. response to the person, who, in sexual relati- The hippocampus is an inhibitor of go- ons, may be normal, suppressed or pathologi- nadotropic hormones secretion (Gallo Rv cal, depending on the normal or pathological 1971) with the horn of Amon, indusium structure. of interested brain formations. The- griseum, girus dentatus, parahippocampus, se will determine the behavior of the normal girus cynguli, the subcalous area, in which, or pathological manifestations of the person. by their older origin, the six brain layers are The normal sexual behavior established by interested. the brain also manifests itself by regulating We also mention cortical formations Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020 13

and subcortical nuclei, with neurons of brain (7), play a very precise role, whether the septal nuclei, which synthesize glyci- or not they fit the effects of normality of the ne, an aminoacid with an inhibitory role individual. in synaptic transmission in the limbic lobe. The amygdalian body, the unnamed sub- Through glycine, the septal nuclei have stance (Reichert), the basal nucleus (Mey- inhibitory action by hyperpolarizing the nert), the olfactory tubercle, the nucleus amygdala, suppressing anger access and accumbens are other formations around the aggressive behavior, initially triggered by callous body. The posterior cortical-medial the amygdala body, and which are specific amygdala has a stimulatory role, and the ante- to the pedophile and the necrophilic kil- rior one has an inhibitory role of pituitary go- ler. This was demonstrated by a classic rat nadotropic hormones. The subcortical nuclei experiment, in which, by destroying the are connected by the stria terminalis with the glycine-producing septal nuclei, the amyg- related amygdala pathway, with the septal nu- dala maintained anger access and aggres- clei, the preoptic area, the thalamic medullary sive behavior, killing rats in the same cage. striae, the dorsal longitudinal tract (Schutz), If glycine As in the mentioned experiment, in the the mammary pe- is injected pedophile, respectively in the pedophile-ne- duncle and the into the crophile, the lack of the neurotransmitter mammo-thalamic amygdala “glycine” in the septal nuclei explains the tract (Popez). Its body in the behavioral disorder characteristic of the pe- lesions modify the same rat, dophile and the criminal sexual behavior in it will no men and women, longer be here being the site aggressive, suppressing the outbursts of of the instinctive, basic and automatic beha- anger. vioral reactions, of fear, aggression or attack of the emotional, primary and visceral sexual As in the mentioned experiment, in the functions. pedophile, respectively in the pedophile-necrophile, the lack of the neurotrans- The neurosecretion of the hypothalamus is mitter “glycine” in the septal nuclei expla- controlled by the brain, modulating the FSH ins the behavioral disorder characteristic and LH secretion of the adenohypophysis. of the pedophile and the criminal. Lesions of the temporal lobe cause major sexual deviations, aberrant sexuality with The neurotransmitters are at the level uncontrolled hypersexuality (Klüver-Bucy of the interneuronal junction (Fig. 6) whe- syndrome), necrophilia, homosexuality, zo- re they trigger the action potential in trans- ophilia, sexual intercourse in non-permitted mitting the nerve influx (7). They have a places that determine public outrage very precise role in the normal functioning of the brain (see case of glycine). With The amygdala body is the seat of violent some exceptions, all neurons, through the behavior, with a reaction of anger and aggres- act of neurosecretion, emit chemicals, whi- sion, which, by lack of neurotransmitters, ch in relation to the level determined in the manifests itself as such in pedophilia. 14 Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020

Disorders characterized by aggression can The amygdala body is rich in enkephalins, also be the effect of limbic or hypothalamic dopamine and glycine (synthesized in the septal lesions, the centers being in the mesen- septal nuclei), acetylcholine, serotonin, nora- cephalic gray matter and in the hypothalamic drenaline, neurotransmitters, which remove the state of anger and aggression, triggered perifornical nucleus. by the amygdala. The absence of neurotransmitters determines the onset of anger, characteristic for the pedophile and the criminal, and there is no balanced behavior of the limbic system. Of all the formations listed, the most important role for behavioral functions is the amygdala body, hippocampus and septal nuclei. The amygdala is the richest formation of the brain in endogenous opioid substan- ces (enkephalins) (involved in transmitting cataleptic* effects) and in neurotransmitters such as dopamine, noradrenaline, serotonin, acetylcholine, glycine. The amygdala body is the center of reactions of fear, anger, aggression, all explaining the violent behavior of the pedophile (which can lead to murder) and controlling the autonomic reactions associated with sexual arousal. The basal nuclei (from the base of the pellucid septum) play a role in sexual behavior and procreation, but also in the determinism of aggressive sexual behavior. Basal ganglia lesions also explain the excessive behavioral reactions to environmental stimuli

Fig.4 Neurotransmitters

(adapted after https://www.turbosquid. *Catalepsy= Pathological condition that appears in some mental com/es/3d-models/3d-max-active-receptor- illnesses and is characterized by an abrupt stiffness of the muscles human-brain/1104769)) and a disturbance of brain functions. Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020 15

. throughout the life of the person concerned, even if the sexual abuse is not intended by Conclusions the victim to the family or those around him. According to Berek / Novak, in the US one third of adult women have suffered such 1. People with bipolar disorder, during the an incident in childhood. Women who have manic phase, can become hypersocial and been sexually abused in childhood, including hypersexual through changes caused by an rape in adulthood, have sexual dysfunctions excessive level of dopamine. The maniacal and difficulties in human intercourse, as well behavioral disturbances further reduce the as in raising and educating their own children self-control capacity of the necrophilic pe- (Berek/Novak). dophile. 6. The limbic system determines the nor- 2. Compulsive psychological hyperero- mal sexual behavior (heterosexual), through tism, present in obsessive-sexual persons, is a mechanism of selective inhibition of the due to neuro-psychic disorders. pathological behavioral factors of the pe- 3. The necrophilic pedophile kills the dophile (associated with brain injuries), ma- child, after which he makes sexual contact nifested by agitation, aggression, physical with the victim. Necrophilia may be the de- and neuro-psychic abuse, child murder, ne- sire of a murderer with macabre tastes, or crophilia. obtaining a necrophilic fantasy, or within the 7. The septal nuclei at the base of the necromultilomania. Necrophil behavior is pellucid septum play a role in sexual and re- caused by brain injury, in the temporal lobe, productive behavior, especially by reversing or may occur in schizophrenia, dementia, or aggressive behavior. Alzheimer’s disease. 8. Regarding the abnormal behavior of 4. Usually, the minor victim is passive, the pedophile and the pedophile criminal, the because of his immature brain, developed connection between the septal nuclei and the according to young age. In this context, the amygdala body, respectively the influence of pedophile, through various forms of solicita- the septal nuclei on the acts of violence cau- tion, convinces the victim to perform mastur- sed by the amygdala, has been proved. Also, bation, fellatio, anal intercourse or intercrural it has been experimentally shown that glyci- intercourse, never being a sexual attraction ne, synthesized in the neurons of the septal of the child. The child, after 3 years of age, nuclei, has inhibitory action by hyperpola- begins to gain sexual orientation towards the rizing on the amygdala, thus removing the opposite sex, being educated in this regard. aggressive behavior, including the criminal This is why sexual identity disorders in abu- one. sed children frequently lead to homosexual attraction in adolescence. In this context, the paper proves that the pedophile’s access to anger and violence on 5. Sexual abuse in childhood causes pro- a child, which he does not differentiate as an found and unforgettable psychological effects adult, is based on morphological lesions of 16 Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020

the brain with well-defined behavioral neuro- dophile. However, the behavioral disorder is psychological manifestations. In the case of complex as long as the pedophile: the murder action, which is followed by the • does not perform the interpretation and pleasure of the necrophilic sexual act, the ne- analysis of the pain determined by the child, uropsychological injuries are complex. for example through the peno-anal or peno- 9 Between the formations of the limbic vaginal act; system there is a balance that allows the civi- • does not raise awareness of the child’s lized coexistence of the people, according to screams of pain when determining acts of se- their normal genetic support. The neocortex xual violence; controls this balance, but only partially, because many of the compartments based in the • in all acts of violence, paradoxically, in arhicortex and the subcortical formations of the absence of a normal sexual motivation, the limbic system escape from the neocortical the pedophile obtains the erection of the pe- control. Also, besides glycine, there may be nis, which allows penetration and rectal co- other neurotransmitters that act in the forma- pulation, proving its complex neuropsycho- tions of the limbic system. logical pathology. This situation involves the mechanisms 13. Normally, the acceptance of the wo- of human behavior, such as dopaminergic, man for the sexual act increases the arousal meso-limbic and meso-cortical, serotoniner- of the partner, causing the penile erection of gic and cholinergic circuits, or neuropeptides the man. In the case of the pedophile, there is from local, neurotransmitter and neuromo- a persistent refusal of the minor victim to the dulatory circuits. The involvement of neuro- abusive requests of the aggressor, hence the transmitters in the pathology of human be- execution of the acts of threat and aggression havior clarifies their involvement in diseases on the victims. Contrary to normal, the erec- such as schizophrenia, epilepsy, Alzheimer’s, tion of the penis, which should be exhausted, chorea, respectively in the manifestations is maintained in the pedophile by the deter- presented in the paper. minism of his brain pathology. 10. The peno-rectal sexual act in the child 14. Dopamine and glycine, like other neu- modifies the anatomical structure of the pe- rotransmitters, may be the cause of behavio- rineal floor and the anal orifice, also produ- ral disorders, caused by lesions of the limbic cing the victim, in parallel, persistent neuro- structures having disorders in the synthesis of psychic injuries for life. the neutrotransmitter substance (7). 12. The lack of cerebral control over the 15. Neurotransmitters and neuromodula- act performed by the pedophile and the cri- tors are involved in mediating the instinctive minal is attested by the serious injuries of and basic behavioral reactions of people in the cerebral anatomical structures. 13. In the the family and society. Behavioral functions present case, a neurotransmitter - glycine is are dependent on the central nervous system involved in the pathological behavior, mani- and any abnormal manifestation is the con- fested by abusive acts of violence of the pe- sequence of brain damage. Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020 17

16. The formations around the corpus ous brain regions. Basically, all neurotrans- callosum constitute the limbic lobe, which mitters, if they exist or interact with receptors functionally forms the Limbic System (LS), on the postsynaptic membrane, alter the the seat of basic behavioral and instinctive structure of the receptor by closing or ope- reactions. LS intervenes in the basal behavior ning a channel for one or more ions (Guyton). in the aggression and attack reactions, accom- 18. Inter-neuronal connections imply the panied by complex somato-motor activities. existence of several neurotransmitters, expla- LS regulates the endocrine functions of ining the abnormal behavior of the pedophile. secretion of gonadotropic hormones, which 19. Excessive sexual behavior is caused in the present case may explain the deter- by the diminution of cortical inhibitory pro- mination of the exaggerated sexual activity cesses, such as in patients presenting with (hypersexuality) of the pedophile, the sexu- psychopaths, epileptic patients, oligophre- al pleasure (the eroticism), respectively the nes, who have an exaggerated sexual impul- erection of the penis in the absence of the se. Other problems can be caused by cerebral, erotic elements of the child, only through an mental disorders, brain trauma, manic-like imaginary perception of the pedophile/mur- arousal, the first phase of the taboos (Stoi- derer. ca). Excessive eroticization causes hypersexuality, which leads to obsession, violent, 17. Of course, between the components aggressive behavior, aspects determined by of the Limbic System there is a balance that neuro-psychic factors (6). differs from individual to individual. Disrup- tion of the glycine elimination function in the 20. The penetration of gonadal hormones septal nuclei, respectively, the lack of this into the cell determines the synthesis of a neurotransmitter, as described in the present new protein (Guyton) with the role of contro- work, maintains aggressive behavior or ca- lling new or altered cellular functions, which uses the child’s death - situations under the could explain, in this respect, the behavioral auspices of the amygdala body secretion, aberrations of pedophiles and criminals. with no communication between the receptors on the cell surface. In this case the neurotransmitter „glycine” does not exist. I point out that in determining specific psychiatric Conflict of interest effects, as well as in the production of many brain lesions, neurotransmitters are involved: The authors have no conflict of interest to • Glycine, in this case, serotonin in schi- make the declaration, had full access to all the zophrenia and many other psychiatric disea- data in the study and takes responsibility for ses; the accuracy of the data analysis. • Dopamine in schizophrenia, behavioral disorders, hallucinations, affective disorders. Usually, the neuro-psychiatric disorder is caused by several neurotransmitters from vari- 18 Journal of Clinical Sexology - Vol. 3;No.1: January- March 2020

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