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The Project Gutenberg Ebook of Syndrome, by Thomas Hoover This Ebook Is for the Use of Anyone Anywhere at No Cost and with Almos

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The Project Gutenberg Ebook of Syndrome, by Thomas Hoover This Ebook Is for the Use of Anyone Anywhere at No Cost and with Almos The Project Gutenberg EBook of Syndrome, by Thomas Hoover This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Project Gutenberg License included with this eBook or online at www.gutenberg.org ** This is a COPYRIGHTED Project Gutenberg eBook, Details Below ** ** Please follow the copyright guidelines in this file. ** Title: Syndrome Author: Thomas Hoover Release Date: November 14, 2010 [EBook #34321] Language: English Character set encoding: UTF-8 *** START OF THIS PROJECT GUTENBERG EBOOK SYNDROME *** Produced by Al Haines ============================================================== This work is licensed under a Creative Commons Attribution 3.0 Unported License, http://creativecommons.org/ ============================================================== SYNDROME They were promised a miracle cure for the deadly diseases destroying their lives. It seemed too good to be true, but to the desperate and dying it was the only chance for survival. Now they’re part of a bizarre secret experiment that reverses the aging process – an experiment gone out of control. To stop the madness, one woman must enter a shocking nightmare world, where scientists control your body – and your mind – and living makes you beg for death . In her mid-thirties, Alexa Hampton runs her own interior design firm in New York’s Soho and has a daily run to keep fit. But now her world is narrowing as a childhood heart mishap increasingly threatens to lethally impact her life. Then out of nowhere her black-sheep younger brother appears and insists she go to a clinic in New Jersey to enter stem-cell clinical trials that are working wonders. The clinic is owned by her brother’s boss, the eccentric millionaire Winston Bartlett. Also interested in the clinic is the medical reporter Stone Aimes, who’s hoping to penetrate Bartlett’s veil of secrecy and find out what’s going on there. He has personal as well as professional reasons for wanting to get closer to Winston Bartlett. He is also a long-ago lover of Alexa’s and still carrying something of a torch for her though they have long been out of touch. As Alexa investigates the clinic, their paths cross and together they slowly uncover the horrifying truth about what can happen when stem-cell technology is taken to its ultimate limit. A bizarre secret experiment to reverse the aging process has gone out of control. Winston Bartlett’s young mistress, the TV personality Kristen Starr, had an anti-aging procedure that went awry and now all her cells are being replaced with new. The side effects are horrific. No one can stop what is happening: she is growing younger, destined to become a child again. Bartlett has had the same procedure and now he knows he’s next. It’s only a matter of time till he too regresses to childhood, and then . no one knows. Alexa and Stone become prisoners in the clinic and then Bartlett and his Dutch medical researcher Karl van der Vliet begin a bizarre experiment on Alexa, hoping to produce antibodies to save Kristen, and Bartlett. In a stunning, blazing finale, Alexa turns the tables on them all, only to discover that she’s now, suddenly unlike anyone else who has ever lived. BOOKS BY THOMAS HOOVER Nonfiction Zen Culture The Zen Experience Fiction The Moghul Caribbee Wall Street Samurai (The Samurai Strategy) Project Daedalus Project Cyclops Life Blood Syndrome All free as e-books at www.thomashoover.info THOMAS HOOVER PINNACLE BOOKS Kensington Publishing Corp. PINNACLE BOOKS are published by Kensington Publishing Corp. 850 Third Avenue New York, NY 10022 Copyright © 2003 by Thomas Hoover Quote copyright © 2000 The New York Times Company. Reprinted by permission. All rights reserved. First Pinnacle Books Printing: November 2003 ISBN:0-7860-1314-1 Key Words THOMAS HOOVER (Author) SYNDROME (Novel: Medical Thriller) Heart disease, Alzheimer’s, Stem Cells, Aortic Stenosis, Medical Columns, Aging, Fountain of Youth, Regenerative Medicine "The potential [of stem cells] for saving lives . may be unlimited. Given the proper signal or environment, stem cells, transplanted into human tissue, can be induced to develop into brain, heart, skin, bone marrow cells—indeed any specialized cells. The scientific research community believes that the transplanted stem cells may be able to regenerate dead or dying human tissue, reversing the progress of disease." Michael J. Fox The New York Times (Op-Ed), November 1, 2000 SYNDROME Chapter 1 Sunday, April 5 6:49 A.M. Alexa Hampton was awakened by a sensation in her chest. The alarm wasn't set to go off for another eleven minutes, but she knew her sleep was finished. Not again! She rolled over and slapped the blue pillowcase. That little sound from her heart and the twinges of angina, that catchall for heart discomfort, was happening more and more now, just as Dr. Ekelman had warned her. But she wasn't going to let it stop her from living her life to the fullest as long as she could, and right now that meant having her morning run. She curled her legs around, onto the floor, reached for a nitroglycerin tab, and slipped it under her tongue. Known as a vasodilator, the nitro lowered the workload on her heart by expanding her veins. It should get her through the workout .... That was when she felt a warm presence rub against her leg. "Hi, baby." Still sucking on the tab, she reached over and tousled Knickers' gray-and-white hair, then pushed it back from her dog's eyes. Her Old English sheepdog, a huge hirsute off-road vehicle, turned and licked her hand. Knickers was ready to hit the trail. She'd been dreaming of Steve when the chest tightness came, and maybe the emotion that stirred up had caused the angina. She still dreamed of him often, and it was always someplace where they had been together and loved, and they were ever on the brink of some disaster. That frequently caused her heart to race, waking her. This time it was the vacation they took six years ago, in the spring. They were sailing off Norman's Cay in the Bahamas. She was raising the jib, the salt spray in her hair, but then she looked up and realized they were about to ram a reef. She felt the dreams were her unconscious telling her to beware her current precarious condition. If, as is said, at the moment of your passing, your entire life flashes before your eyes, then the dreams were like that, only in slow motion. It was as though she were being prepared for something. The dreams were a premonition. She had a pretty good idea of what. Ally had had rheumatic fever when she was five, which went undetected long enough to scar a valve in her heart. The formal name was rheumatoid aortic stenosis, a rare, almost freakish condition that had shaped her entire life. The pediatrician at Mount Sinai had told her parents they should think twice about allowing her to engage in any vigorous activity. Her heart's function could be deceptively normal during childhood but when she got older . Well, why stress that organ now and hasten the inevitable day when it could no longer keep up with the rest of her body? She had refused to listen. She'd played volleyball in grade school, basketball in high school, and she became a disciplined runner when she went to Columbia to study architecture. She wanted to prove that you could make your heart stronger if you believed hard enough and wanted to live hard enough. Now, though, it was all catching up. She'd had a complete checkup two weeks ago Thursday, including a stress test and Doppler echocardiogram, and Dr. Ekelman had laid out the situation, gazing over her half-lens glasses and pulling at her chin. The normal twinkle in her eyes was entirely absent. "Alexa, your condition has begun worsening. There's a clear aortic murmur now when your pulse goes up. How long can you go on living in denial? You really can't keep on stressing your heart the way you have been. You can have a normal life, but it's got to be low-key. Don't push your luck." "Living half a life is so depressing," she'd declared, not entirely sure she meant it. "It's almost worse than none at all." "Ally, I'm warning you. If you start having chest sensations that don't respond to nitro, call me immediately. I mean that. There's a new drug, Ranolazine, that temporarily shifts your heart over to using glucose as a fuel instead of fatty acids and provides more energy for a given amount of oxygen. It will make the pain back off, but I only want to start you on that as a last resort. That's the final stop before open-heart surgery and a prosthetic aortic valve." Day by day, the illusion of normality was getting harder and harder to maintain. She had been playing second violin in an amateur string quartet called the West Village Oldies, but a month ago she'd had to drop out. She didn't have the endurance to practice enough to keep up with the others. Blast. It was having to give up things you love that really hurt. Still, she was determined to keep a positive attitude. There was your heart, and then there was heart. You had to understand the difference. She lay back to wait for the alarm and try to compose her mind.
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