CARCINOGENESIS Specialty Section | Society of Toxicology | Founded 1986
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Summer Newsletter July 2020 CARCINOGENESIS Specialty Section | Society of Toxicology | Founded 1986 Many thanks to our members and In this issue: Letter fom the President officers who were involved in the CSS during the past year, especially those I hope you are all staying safe and well President’s Greeting 1 participated in organizing and during this challenging time. It is my presenting well-received webinars. We Officer Introduction 2 distinct honor and privilege to share continue to provide our members with with you the Summer 2020 Member Spotlight 3 webinars and welcome ideas and newsletter from CSS. In this issue of the proposals. If you have ideas for a Treasury Report 4 newsletter, you will find an introduction webinar or webinar series or are to our current officers, treasure report, Award Recipients 5 interested in presenting, please recognition of award winners, member contact the CSS leadership. Special Award Details 7 n e w s a n d f u t u r e e v e n t s thanks to Sumira Phatak our student announcements. Member News 8 volunteer who has been extremely Member Spotlight 9 I would like to congratulate our student helpful in generating our newsletters. and postdoc award recipients. Special We appreciated the submission of Upcoming Events 10 thanks to those in particular Amy Wang symposia and workshops from our (NTP) and Xuefeng Ren (The University members for the 60th annual meeting at Buffalo) who reviewed their in Orlando, March 2021. I would like to Current CSS Officers materials. Meanwhile, I am excited to encourage members to resubmit their share with you that our newly formed symposia for the 2022 meeting or James A. Swenberg Endowment fund present webinars to CSS if the Program Zemin Wang, President has reached permanent status. Starting Committee does not accept your [email protected] 2021, we will set up “James A. submission for the 2021 meeting. Swenberg Carcinogenesis Merit In addition, I’d like to welcome our new Award” using this fund to recognize an Chris Corton, Vice President CSS officers for the 2020-2021 year outstanding junior faculty for his/her [email protected] and extend my heartfelt thanks to contribution to the advancements in those officers who rotated off for their Chad Brocker, VP Elect understanding the mechanisms of service. This winter, we will have four environmental agent-associated [email protected] positions open for 2021: VP-elect, carcinogenesis. Eligibility, application Councilor, graduate student and Udayan Apte, Past President requirements and selection criteria will postdoc representatives. Please be announced later this summer. It’s [email protected] consider nominating yourself or your still early but please think about the colleagues who are interested in Gina Hilton, Secretary/Treasurer abstracts for your students and post- serving the CSS communities. Udayan [email protected] docs for the Orlando meeting. Also, will be leading the nomination please encourage your students and committee. James Kim, Councilor post-docs to join the CSS and let them [email protected] know about the opportunities and I look forward to Jamie Bernard, Councilor awards offered through CSS. Our working with you leadership is always available to throughout the [email protected] answer any questions from potential year. Please do Rance Nault, Postdoc Rep new members. not hesitate to contact me or I would also like to congratulate Dr. [email protected] any members of James E. Klaunig, a life-time member t h e exe c u t i v e Luma Melo, Student Rep a n d t w o - t i m e C S S p r e s i d e n t committee with (1998/1999 and 2015/2016) for [email protected] any suggestions receiving the 2020 SOT Education o r i t e m s o f Sumira Phatak, Editor-in-Chief A w a r d . C o n g r a t u l a t i o n s J i m ! i n t e r e s t y o u Congratulations also to Lora Arnold for [email protected] would like to be her retirement from UNMC after an included in the outstanding 43-year career. Lora has next newsletter. Outgoing Officers b e e n a c t i v e i n t h e S o c i e t y o f Toxicology and served as CSS senior Zemin Wang, MD, PhD, DABT Timothy Fennell, Past President councilor. You will be sincerely missed, Lora. We wish you well and enjoy every President of CSS, 2020-2021 [email protected] minute of your retirement! SOT CSS .110 Summer Newsletter July 2020 Officer Introduction at Karolinska University, in Huddinge, Sweden laboratory, my work focused on how hepatic President from 1994 to 1995. He is on the editorial boards nuclear receptors influence metabolism and Zemin Wang, MD, PhD, DABT of 6 journals including as the Associate Editor for contribute to liver cancer progression. I left NCI Toxicologist Toxicological Sciences and has been a reviewer in 2018 to work as a Toxicologist in the Office of and/or chair on over 30 peer review committees Science at the Center for Tobacco Products at the US Food and Drug Administration for NIH/NIEHS grants. Dr. Corton has been an U.S. Food and Drug Administration. Dr. Wang serves as toxicology subject matter active member of SOT since 1992, serving as When I was in graduate school SOT really opened expert in an advisory capacity for both regulatory Chair of the Continuing Education and Current my eyes to the wide array of career paths that are and research projects and conducts research in Concepts in Toxicology Committees, in addition available to Toxicologists. SOT meetings provided supporting safety assessment of cosmetic to past President of the Molecular Biology a great opportunity to learn about developing ingredients regarding their human health risks, in Specialty Section. He was the recipient of the areas of toxicological research and helped me particular cancers, within the FDA Cosmetics SOT 2010 AstraZeneca Traveling Lectureship develop as a scientist. The annual SOT meeting Division. Prior to joining FDA in November 2017, award. He has organized and co-chaired continues to serve as an outstanding place to he was a research scientist at Indiana University numerous symposia, roundtables, and CE network and is a great way to meet new studying the modes of action of chemical courses held at SOT meetings. He has studied colleagues as well as catch up with old friends. induced tumors in rodents and their relevance to chemical carcinogenesis for almost 30 years An interesting paper I’ve read this year is human health risks. Dr. Wang received his focusing on the use of toxicogenomics to “Electronic-cigarette smoke induces lung medical training and master’s degree in determine mechanisms of nongenotoxic adenocarcinoma and bladder urothelial Pathology from China. He obtained his doctorate carcinogens. Lately, his group has developed hyperplasia in mice.” (PMID:31591243) in Environmental Toxicology from Texas Tech methods for the prediction of cancer using gene University in 2007, and subsequently worked as expression profiling after short-term exposures. postdoc fellow in chemical carcinogenesis at SOT is a wonderful organization that helped me Past President Indiana University School of Medicine, and to grow as a scientist and leader. First, the SOT cancer genetics and genomics at LSUHSC. Dr. has been and continues to be a way to develop Udayan Apte, PhD, DABT Wang holds American Board of Toxicology connections with talented investigators across Associate Professor certification since 2013 and has been a member different disciplines allowing for exchange of University of Kansas Medical Center of SOT since 2004. He authored over 45 peer ideas and building collaborations. Second, my reviewed articles in cancer and toxicology various committee appointments have allowed Dr. Apte received his journals, 3 book chapters, and over 50 me to gain valuable experience and skills as a d o c t o r a t e f r o m t h e conference presentations. He has served SOT in contributor and leader on a number of efforts. University of Louisiana at a number of other capacities including vice Lastly, the Society has helped me to get out of my M o n ro e i n 2 0 0 3 . H e president elect, councilor/chair of award comfort zone of my particular research area and completed postdoctoral committee for CSS, award committee for consider how to think about solving problems appointments at Texas RASS, councilor/secretary for AACT-SIG and chair from a more systems biology perspective. An A&M University from 2003 of the AACT award committee. interesting paper I’ve read this year is to 2004, as well as the University of Pittsburgh Sustained involvement with SOT, since the 2nd “Quantitative Transcriptional Biomarkers of from 2004 to 2008. His year of my graduate school in 2004, has kept me Xenobiotic Receptor Activation in Rat Liver for research interests include abreast of the latest development in the field, t h e E a r l y A s s e s s m e n t o f D r u g S a f e t y understanding shaped my career path, and provided me with Liabilities.” (PMID:32119089) A group of gene m e c h a n i s m s o f l i v e r unmatched access to the world’s largest expression biomarkers in rat liver identify cancer pathogenesis, liver regeneration, and toxicologist’s own networking platform. An chemical mechanism of action, including tumor persistent organic pollutant-induced chemical interesting paper I’ve read this year is “Cell induction, that could inform candidate selection carcinogenesis.