Contents Volume 63 Issue 10 | October 2014

Commentaries 1578 Altered intestinal microbiota and blood 1529 Are we improving disease outcomes in IBD? T cell phenotype are shared by patients with A view from the epidemiology side Crohn’s disease and their unaffected siblings C Gower-Rousseau, G Savoye, J-F Colombel, C R Hedin, N E McCarthy, P Louis, L Peyrin-Biroulet F M Farquharson, S McCartney, K Taylor, N J Prescott, T Murrells, A J Stagg, K Whelan, Gut: first published as on 1 October 2014. Downloaded from Caption: The magnificent Vienna City Hall. Vienna J O Lindsay hosts this year’s UEGW. The Gut family wish 1530 Revival of 5-HT3 antagonism as treatment everyone a very successful meeting. of IBS-D? G Barbara 1587 ClC-3 chloride channel/antiporter defect An international journal of contributes to infl ammatory bowel disease gastroenterology and hepatology 1532 Clearance of HBV markers and HCC risk: in humans and mice : 13.319 who is safe? L-Y Huang, Q He, S-J Liang, Y-X Su, L-X Xiong, Editor Q-Q Wu, Q-Y Wu, J Tao, J-P Wang, Y-B Tang, Emad El-Omar (UK) H M Diepolder X-F Lv, J Liu, Y-Y Guan, R-P Pang, J-G Zhou Deputy Editor (Hepatology) Alexander Gerbes (Germany) 1533 A novel twist in polycystic liver disease Deputy Editor (Luminal 1596 Detection of bacterial DNA in lymph nodes W R Cnossen, J P H Drenth Gastroenterology) of Crohn’s disease patients using high William Grady (USA) throughput sequencing Deputy Editor (Endoscopy) Original articles C L O’Brien, P Pavli, D M Gordon, G E Allison Thomas Rösch (Germany) Oesophagus Associate Editors Matias Avila (Spain) 1535 Long-term recurrence of neoplasia and Barrett’s 1607 Changes in medical treatment and surgery Martin Blaser (USA) epithelium after complete endoscopic resection rates in infl ammatory bowel disease: Guy Boeckxstaens (Belguim) M Anders, C Bähr, M A El-Masry, A H Marx, a nationwide cohort study 1979–2011 Thomas Gress (Germany) M Koch, S Seewald, G Schachschal, A Adler, Arthur Kaser (UK) C Rungoe, E Langholz, M Andersson, S Basit, Ernst Kuipers (The Netherlands) N Soehendra, J Izbicki, P Neuhaus, H Pohl, T Rösch N M Nielsen, J Wohlfahrt, T Jess Jake Liang (USA) Julian Panes (Spain) 1544 Use of proton pump inhibitors after antirefl ux Neurogastroenterology http://gut.bmj.com/ Herbert Tilg (Austria) surgery: a nationwide register-based Fabien Zoulim (France) 1617 A randomised trial of ondansetron for Editorial Offi ce follow-up study the treatment of irritable bowel syndrome Gut A Lødrup, A Pottegård, J Hallas, P Bytzer OPEN ACCESS with diarrhoea BMJ Journals K Garsed, J Chernova, M Hastings, C Lam, BMA House, Tavistock Square London, WC1H 9JR, UK Helicobacter pylori L Marciani, G Singh, A Henry, I Hall, P Whorwell,

T: +44 (0)20 7383 6394 1550 CCL20/CCR6-mediated migration of regulatory R Spiller on September 25, 2021 by guest. Protected copyright. F: +44 (0)20 7383 6668 T cells to the Helicobacter pylori-infected human E: [email protected] OPEN ACCESS gastric mucosa Twitter: @Gut_BMJ Pancreas K W Cook, D P Letley, R J M Ingram, E Staples, 1626 mAb Das-1 is specifi c for high-risk and ISSN: 0017-5749 (print) H Skjoldmose, J C Atherton, K Robinson ISSN: 1468-3288 (online) malignant intraductal papillary mucinous neoplasm (IPMN) Disclaimer: Gut is owned and published by BMJ Publishing Group Ltd, a wholly owned subsidiary Endoscopy K K Das, H Xiao, X Geng, of the British Medical Association and the British Society of Gastroenterology. The owners grant 1560 Carbon dioxide insuffl ation improves the C Fernandez-del-Castillo, V Morales-Oyarvide, editorial freedom to the Editor of Gut. Gut follows intubation depth and total enteroscopy rate E Daglilar, D G Forcione, B C Bounds, W R Brugge, guidelines on editorial independence produced by the World Association of Medical Editors and the in single-balloon enteroscopy: a randomised, M B Pitman, M Mino-Kenudson, K M Das code on good publication practice of the Committee on Publication Ethics. controlled, double-blind trial ᭤ Gut is intended for medical professionals and is X Li, Y-J Zhao, J Dai, X-B Li, H-B Xue, Y Zhang, MORE CONTENTS provided without warranty, express or implied. Statements in the Journal are the responsibility G-S Xiong, K Ohtsuka, Y-J Gao, Q Liu, Y Song, of their authors and advertisers and not authors’ J-Y Fang, Z-Z Ge institutions, the BMJ Publishing Group, the British This article has been chosen by the Editor to be of special interest Society of Gastroenterology or the BMA unless or importance and is freely available online. otherwise specifi ed or determined by law. Acceptance of advertising does not imply Infl ammatory bowel disease This article has been made freely available online under the BMJ endorsement. Journals Open Access scheme. To the fullest extent permitted by law, the BMJ 1566 Bacterial protein signals are associated Publishing Group shall not be liable for any loss, with Crohn’s disease OPEN ACCESS See http://gut.bmj.com/site/about/guidelines.xhtml#open injury or damage resulting from the use of Gut or any information in it whether based on contract, OPEN ACCESS C Juste, D P Kreil, C Beauvallet, A Guillot, S Vaca, tort or otherwise. Readers are advised to verify any information they choose to rely on. C Carapito, S Mondot, P Sykacek, H Sokol, F Blon, Copyright © 2014 BMJ Publishing Group Ltd and P Lepercq, F Levenez, B Valot, W Carré, V Loux, British Society of Gastroenterology. All rights This journal is a member of and subscribes to the principles of the reserved; no part of this publication may be N Pons, O David, B Schaeffer, P Lepage, P Martin, Committee on Publication Ethics reproduced, stored in a retrieval system or V Monnet, P Seksik, L Beaugerie, S D Ehrlich, http://publicationethics.org/ transmitted in any form or by any means, electronic, mechanical, photocopying, recording J-F Gibrat, A Van Dorsselaer, J Doré or otherwise without prior permission Gut is published by BMJ Publishing Group Ltd, typeset by Techset and printed in the UK on acid-free paper. Gut (ISSN: 0017-5749) is published monthly by BMJ Publishing Group and is distributed in the USA by Air Business Ltd. Periodicals postage paid at Jamaica NY 11431 POSTMASTER: send address changes to Gut, Air Business Ltd, c/o Worldnet Shipping Inc., 156-15, 146th Avenue, 2nd Floor, Jamaica, NY 11434, USA.

gutjnl_63_10_TOC.indd 1 01/09/14 4:09 PM Contents Volume 63 Issue 10 | GUT October 2014

Hepatology Recent advances in basic science Receive regular table of contents by email. 1635 PTEN antagonises Tcl1/hnRNPK-mediated G6PD 1668 Moving towards personalised therapy in Register using this QR code. pre-mRNA splicing which contributes patients with hepatocellular carcinoma: to hepatocarcinogenesis the role of the microenvironment X Hong, R Song, H Song, T Zheng, J Wang, Y Liang, G Giannelli, B Rani, F Dituri, Y Cao, G Palasciano

S Qi, Z Lu, X Song, H Jiang, L Liu, Z Zhang Gut: first published as on 1 October 2014. Downloaded from Editor’s quiz: GI snapshot 1648 Spontaneous seroclearance of hepatitis 1606 Fever and right upper quadrant pain B seromarkers and subsequent risk of in a 24-year-old male hepatocellular carcinoma V T F Cheung, D Joshi, Z Amin, G J Webster J Liu, H-I Yang, M-H Lee, S-N Lu, C-L Jen, R Batrla-Utermann, L-Y Wang, S-L You, C K Hsiao, P-J Chen, C-J Chen, for the R.E.V.E.A.L.-HBV JournalScan Study Group 1677 GI highlights from the literature M H McLean 1658 Inhibition of metalloprotease hyperactivity in cystic cholangiocytes halts the development PostScript of polycystic liver diseases 1680 Book review A D Urribarri, P Munoz-Garrido, M J Perugorria, O Erice, M Merino-Azpitarte, A Arbelaiz, E Lozano, E Hijona, R Jiménez-Agüero, M G Fernandez-Barrena, J P Jimeno, M Marzioni, J J G Marin, T V Masyuk, N F LaRusso, J Prieto, L Bujanda, J M Banales http://gut.bmj.com/ on September 25, 2021 by guest. Protected copyright.

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