Traditional Posters
Traditional Poster MRS/MRSI Aquisition Exhibition Hall 1271-1304 Monday 8:15 - 10:15 Metabolite cycled density-weighted concentric rings k-space trajectory (DW-CRT) enables 1H magnetic resonance spectroscopic imaging at 3 Tesla in a clinically feasible timeframe Adam Steel1,2, Mark Chiew3, Peter Jezzard4, Natalie Voets4, Puneet Plaha4, M. Albert Thomas5, Charlotte J Stagg4, and Uzay E Emir6 1Nuffield Department of Medicine, University of Oxford, Headington, United Kingdom, 2National Institute of Mental Health, National Institutes of Health, Bethesda, DC, United States, 3Nuffield Department of Clinical Neuroscience, University of Oxford, Headington, United Kingdom, 4Nuffield Department of Clinical Neurosciences, University of Oxford, Headington, 1271 United Kingdom, 5Department of Radiology, University of California Los Angelas, Los Angeles, CA, United States, 6School of Health Sciences, Purdue University, West Lafayette, IN, United States In this study, we demonstrate that a metabolite-cycled semi-LASER pulse localization with density-weighted concentric rings trajectory (DW-CRT) enables high-resolution MRSI to be acquired at 3 Tesla within a clinically feasible acquisition time. High-resolution (5 x 5 x 10 mm3) DW-CRT feasibility at 3T was assessed in 6 healthy volunteers. Subsequently, the clinical utility of this approach was demonstrated by mapping the presence of 2-HG in a patient with a grade III oligodendroglioma tumor. Standardized Parameterization of Echo-Planar Compressed Sensing MRSI Acquisition and Reconstruction Jason C. Crane1, Marram P Olson1, Yan Li1, Maryam Vareth1, Hsin-Yu Chen1, Zihan Zhu1, Sukumar Subramaniam1, Peder E.Z. Larson1, Duan Xu1, Daniel B. Vigneron1, and Sarah J. Nelson1 1272 1Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States Advanced MRSI acquisition strategies can be complex to implement and require customized reconstruction software, typically designed for a specific raw file format and that relies upon a priori knowledge of the specific implementation of the pulse sequence being applied.
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