Arkusz1 Strona 1 CSB-E13697m CSB-E18032c CSB-E08097h CSB-E08098r P01023 CSB-E08959h CSB-E09040h CSB-E14102m CSB-E13008r CSB-E091

Total Page:16

File Type:pdf, Size:1020Kb

Arkusz1 Strona 1 CSB-E13697m CSB-E18032c CSB-E08097h CSB-E08098r P01023 CSB-E08959h CSB-E09040h CSB-E14102m CSB-E13008r CSB-E091 Arkusz1 Uniprot ID Code Product Name CSB-E13697m Mouse 1,25-dihydroxyvitamin D3 (DVD/DHVD3) ELISA kit CSB-E18032c Dog 25-hydroxy vitamin D3(25 HVD3)ELISA Kit CSB-E08097h Human 25-hydroxy vitamin D3,25HVD3 ELISA Kit CSB-E08098r Rat 25-hydroxy vitamin D3(25 HVD3)ELISA Kit P01023 CSB-E08959h Human α2 macroglobulin,α2 MG ELISA Kit CSB-E09040h Human Arachidonic Acid,AA ELISA Kit CSB-E14102m Mouse Arachidonic Acid(AA) ELISA Kit CSB-E13008r Rat Arachidonic Acid(AA) ELISA Kit CSB-E09159Pl Plant hormone abscisic acid,ABA ELISA Kit P09470 CSB-E04492m Mouse Angiotensin converting enzyme,ACE ELISA Kit CSB-E04486h Human Activin A,ACV-A ELISA Kit CSB-E04502m Mouse Activin A,ACV-A ELISA Kit CSB-E04503r Rat Activin A,ACV-A ELISA Kit C9DFG2 CSB-EL001366HA Hamster adiponectin, C1Q and collagen domain containing (ADIPOQ)ELISA kit Q15848 CSB-E07270h Human adiponectin,ADP ELISA Kit Q60994 CSB-E07272m Mouse adiponectin,ADP ELISA Kit Q8K3R4 CSB-E07271r Rat adiponectin,ADP ELISA Kit CSB-E05005h Human Adenovirus (ADV)antibody(IgG)ELISA Kit CSB-E05006h Human adenovirus (ADV) antibody (IgM) ELISA kit P02771 CSB-E04770h Human Alpha-fetoprotein,AFP ELISA Kit P25304 CSB-EL001461RA Rat Agrin(AGRN) ELISA kit O00253 CSB-E09299h Human Agouti Related Protein,AGRP ELISA Kit P29699 CSB-E14042m Mouse Fetuin A ELISA Kit P49822 CSB-E15757c Dog Albumin(Alb) ELISA Kit P85295 CSB-E15758G Goat Albumin (Alb)ELISA Kit P35747 CSB-E16205Hs Horse Albumin(Alb) ELISA Kit P02768 CSB-E08970h Human microalbunminuria(MAU/ALB) ELISA kit P07724 CSB-E13878m Mouse Albumin (Alb)ELISA Kit P08835 CSB-E16207p Pig Albumin (Alb) ELISA Kit P49065 CSB-E16204Rb Rabbit Albumin(Alb) ELISA Kit P14639 CSB-E15839Sh Sheep Albumin (Alb)ELISA Kit P00978 CSB-EL001654BO Bovine alpha-1-microglobulin/bikunin precursor (AMBP) ELISA kit P02760 CSB-E11316h Human alpha-1-microglobulin/bikunin precursor,AMBP ELISA Kit Q07456 CSB-E09776m Mouse alpha-1-microglobulin/bikunin precursor (AMBP) ELISA kit P04366 CSB-EL001654PI Pig alpha-1-microglobulin/bikunin precursor (AMBP) ELISA kit Q64240 CSB-EL001654RA Rat alpha-1-microglobulin/bikunin precursor (AMBP) ELISA kit P03950 CSB-E04498h Human Angiogenin,ANG ELISA Kit O18920 CSB-EL001706BO Bovine Angiopoietin-1(ANGPT1) ELISA kit Q15389 CSB-EL001706HUHuman Angiopoietin-1(ANGPT1) ELISA kit O15123 CSB-E04500h Human Angiopoietin 2,ANG-2 ELISA Kit Q9Y5C1 CSB-E11724h Human angiopoietin-like protein 3,ANGPTL3 ELISA Kit Q9R182 CSB-EL001711MOMouse Angiopoietin-related protein 3(ANGPTL3) ELISA kit Q9BY76 CSB-EL001712HUHuman Angiopoietin-related protein 4(ANGPTL4) ELISA kit P02647 CSB-E08103h Human apolipoprotein A1 (Apo-A1) ELISA Kit Q6Q788 CSB-E11901h Human apolipoprotein A5 (Apo-A5) ELISA Kit Strona 1 Arkusz1 Q8C7G5 CSB-E16332m Mouse Apolipoprotein A5(apo-A5)ELISA Kit Q9QUH3 CSB-E16334r Rat Apolipoprotein A5(apo-A5)ELISA Kit C1KBZ5 CSB-E16333p Pig Apolipoprotein A5(apo-A5)ELISA Kit P11682 CSB-EL001918CH Chicken Apolipoprotein B(APOB) ELISA kit P11682 CSB-EL001918HA Hamster apolipoprotein B (APOB) ELISA kit P04114 CSB-E08100h Human apolipoprotein B100 (Apo-B100) ELISA Kit E9Q414 CSB-EL001918MOMouse Apolipoprotein B(APOB) ELISA kit Q7TMA5 CSB-E08102r Rat apolipoprotein B100 (Apo-B100) ELISA Kit P17165 CSB-E09805Rb Rabbit apolipoprotein B100 (Apo-B100) ELISA Kit Q03247 CSB-EL001936BO Bovine Apolipoprotein E(APOE) ELISA kit P18649 CSB-EL001936DODog Apolipoprotein E(APOE) ELISA kit P23529 CSB-EL001936GUGuinea pig Apolipoprotein E(APOE) ELISA kit P02649 CSB-E09748h Human apolipoprotein E (Apo-E) ELISA Kit P08226 CSB-E09750m Mouse apolipoprotein E (Apo-E) ELISA Kit P18287 CSB-E09806Rb Rabbit apolipoprotein E (Apo-E) ELISA Kit P02650 CSB-E09749r Rat apolipoprotein E (Apo-E) ELISA Kit Q7M2U8 CSB-EL001936SH Sheep Apolipoprotein E(APOE) ELISA kit P18650 CSB-E17889p Pig apolipoprotein E (Apo-E) ELISA Kit Q61176 CSB-EL002005MOMouse Arginase-1(ARG1) ELISA kit P23560 CSB-E04501h Human Brain derived neurotrophic factor,BDNF ELISA Kit P06681 CSB-EL003658HUHuman Complement C2(C2) ELISA kit P01024 CSB-E08665h Human Complement 3,C3 ELISA Kit P01031 CSB-E13615h Human Complement 5,C5 ELISA Kit CSB-E08514m Mouse Complement fragment 5a,C5a ELISA Kit P00915 CSB-EL004364HUHuman Carbonic anhydrase 1(CA1) ELISA kit Q16790 CSB-E13266h Human Carbonic Anhydrase 9(CA9) ELISA Kit P51671 CSB-E04533h Human eosinophil chemotactic factor,ECF ELISA Kit Q16627 CSB-EL004777HUHuman C-C motif chemokine 14(CCL14) ELISA kit Q16663 CSB-E07997h Human macrophage inflammatory protein 5,MIP-5 ELISA Kit O15467 CSB-EL004779HUHuman C-C motif chemokine 16(CCL16) ELISA kit Q92583 CSB-E09257h Human thymus activation regulated chemokine,TARC ELISA Kit P52203 CSB-E15747c Dog Monocyte Chemotactic Protein 1/Monocyte Chemotactic And Activating Factor(MCP-1/MCAF) ELISA kit P13500 CSB-E04655h Human monocyte chemotactic protein 1/monocyte chemotactic and activating factor,MCP-1/MCAF ELISA kit O00626 CSB-E04660h Human Macrophage-Derived Chemokine (MDC/CCL22) ELISA kit O88430 CSB-E04661m Mouse Macrophage-Derived Chemokine,MDC ELISA kit P55773 CSB-E07309h Human Myeloid Progenitor Inhibitory Factor 1,MPIF-1 ELISA Kit O00175 CSB-E10360h Human Eotaxin 2/CCL24 ELISA Kit Q9Y4X3 CSB-E09125h Human C-C motif chemokine 27 (CCL27) ELISA Kit Q8HYS0 CSB-EL004800DODog C-C motif chemokine 5(CCL5) ELISA kit P97272 CSB-EL004800GUGuinea pig C-C motif chemokine 5(CCL5) ELISA kit P13501 CSB-E17375h Human C-C motif chemokine 5 (CCL5/D17S136E/SCYA5) ELISA kit P08571 CSB-E13199h Human soluble cluster of differentiation 14,sCD14 ELISA Kit P27512 CSB-EL004936MOMouse Tumor necrosis factor receptor superfamily member 5(CD40) ELISA kit P29965 CSB-E04716h Human Soluble Cluster of differentiation 40 ligand,sCD40L ELISA Kit P18181 CSB-EL004941MOMouse CD48 antigen(CD48) ELISA kit Q00609 CSB-EL004959MOMouse T-lymphocyte activation antigen CD80(CD80) ELISA kit Strona 2 Arkusz1 P22223 CSB-E08955h Human Placenta Cadherin,P-cad ELISA Kit P13688 CSB-EL005157HUHuman Carcinoembryonic antigen-related cell adhesion molecule 1(CEACAM1) ELISA kit P06731 CSB-E04767h Human carcinoembryonic antigen,CEA ELISA Kit P00746 CSB-E14369h Human Adipsin ELISA Kit P36222 CSB-E13608h Human Chitinase-3-like Protein 1(YKL-40/CHI3L1)ELISA Kit P17697 CSB-EL005595BO Bovine Clusterin(CLU) ELISA kit P25473 CSB-E13770c Dog clusterin,CLU ELISA Kit Q06890 CSB-EL005595MOMouse Clusterin(CLU) ELISA kit Q9XSC5 CSB-EL005595RB Rabbit Clusterin(CLU) ELISA kit P17698 CSB-EL005595SH Sheep Clusterin(CLU) ELISA kit CSB-E13064B Bovine Cortisol ELISA Kit CSB-E14303c Canine Cortisol ELISA Kit CSB-E08487f Fish Cortisol ELISA Kit CSB-E18048G Goat Cortisol ELISA Kit CSB-E15960Gp Guinea Pig Cortisol ELISA Kit CSB-E05111h Human Cortisol ELISA Kit CSB-E05113m Mouse Cortisol ELISA Kit CSB-E06811p Pig Cortisol ELISA Kit CSB-E05112r Rat Cortisol ELISA Kit Q96IY4 CSB-E08778h Human Thrombin activatable fibrinolysis inhibitor,TAFI ELISA Kit CSB-E13632Mk Cynomologus Monkey C-Peptide ELISA Kit CSB-E05066h Human C-Peptide ELISA Kit P07141 CSB-E04659m Mouse Macrophage Colony-Stimulating Factor,M-CSF ELISA kit P04141 CSB-E04568h Human Granulocyte-Macrophage Colony Stimulating Factor,GM-CSF ELISA Kit P01034 CSB-E08384h Human Cystatin C,Cys-C ELISA Kit P21460 CSB-E08386m Mouse Cystatin C,Cys-C ELISA Kit P04080 CSB-E16835h Human Cystatin-B (CSTB/CST6/STFB) ELISA kit P07711 CSB-E17971h Human Cathepsin L1 (CTSL1/CTSL) ELISA kit P25774 CSB-E13722h Human Cathepsin S (CTSS) ELISA Kit P78423 CSB-E04558h Human Fractalkine,FK ELISA Kit O14625 CSB-E09023h Human Interferon inducible T-cell Chemoattractant,I-TAC ELISA Kit O43927 CSB-E10019h Human B-Lymphocyte Chemoattractant 1,BLC-1 ELISA Kit O55038 CSB-E16832m Mouse C-X-C motif chemokine 13 (Cxcl13/Blc/Scyb13) ELISA kit Q9H2A7 CSB-E08871h Human CXC-chemokine ligand 16,CXCL16 ELISA Kit P30348 CSB-E07419r Rat macrophage inflammatory protein 2,MIP-2 ELISA kit P42830 CSB-E08178h Human Epithelial neutrophil activating peptide 78 (ENA-78/CXCL5) ELISA Kit P80162 CSB-E09990h Human granulocyte chemotactic protein-2,GCP-2 ELISA Kit CSB-E13342r Rat 1,25-dihydroxyvitamin D3(1,25 DHVD3) ELISA Kit P07585 CSB-E16522h Human Decorin/Bone proteoglycan II (DCN) ELISA Kit P28654 CSB-EL006554MOMouse Decorin(DCN) ELISA kit O54908 CSB-EL006920MOMouse Dickkopf-related protein 1(DKK1) ELISA kit Q9UBP4 CSB-E13607h Human Dickkopf 3,DKK3 ELISA Kit CSB-E08173b Bovine Estradiol,E2 ELISA Kit CSB-E12013C Chicken Estradiol,E2 ELISA Kit CSB-E06846c Canine Estradiol,E2 ELISA Kit CSB-E13017Fh Fish Estradiol(E2) ELISA kit Strona 3 Arkusz1 CSB-E13505G Goat Estradiol(E2) ELISA Kit CSB-E05108h Human Estradiol,E2 ELISA Kit CSB-E16426Mk Monkey estradiol (E2) ELISA kit CSB-E05109m Mouse Estradiol,E2 ELISA Kit CSB-E06844p Pig Estradiol,E2 ELISA KIT CSB-E05110r Rat Estradiol,E2 ELISA Kit CSB-E13172Sh Sheep Estradiol(E2) ELISA Kit CSB-E05010h Human epstein-barr virus (EBv)antibody (IgG) ELISA Kit CSB-E05012h Human epstein-barr virus(Ebv) antibody(IgM) ELISA Kit CSB-E14233h Human EchoVirus (ECHO) antibody (IgG) ELISA kit CSB-E05003h Human EchoVirus (ECHO) antibody (IgM) ELISA kit P01133 CSB-E08027h Human Epidermal growth factor,EGF ELISA Kit P17813 CSB-E10030h Human Soluble Endoglin,sENG/sCD105 ELISA Kit Q63961 CSB-E09921m Mouse Soluble Endoglin,ENG/sCD105 ELISA Kit P09104 CSB-E07961h Human Neuron-specific enolase,NSE ELISA Kit P07321 CSB-E04539m Mouse Erythropoietin,EPO ELISA Kit CSB-E13074B Bovine folic acid,FA ELISA Kit CSB-E08759c Canine Folic acid,FA ELISA Kit CSB-E17109h Human Folic acid(FA) ELISA Kit CSB-E08758m Mouse Folic acid,FA ELISA Kit CSB-E08757r Rat Folic acid,FA ELISA Kit P12104 CSB-E08024h Human intestinal fatty acid binding
Recommended publications
  • Supplemental Information
    Supplemental information Dissection of the genomic structure of the miR-183/96/182 gene. Previously, we showed that the miR-183/96/182 cluster is an intergenic miRNA cluster, located in a ~60-kb interval between the genes encoding nuclear respiratory factor-1 (Nrf1) and ubiquitin-conjugating enzyme E2H (Ube2h) on mouse chr6qA3.3 (1). To start to uncover the genomic structure of the miR- 183/96/182 gene, we first studied genomic features around miR-183/96/182 in the UCSC genome browser (http://genome.UCSC.edu/), and identified two CpG islands 3.4-6.5 kb 5’ of pre-miR-183, the most 5’ miRNA of the cluster (Fig. 1A; Fig. S1 and Seq. S1). A cDNA clone, AK044220, located at 3.2-4.6 kb 5’ to pre-miR-183, encompasses the second CpG island (Fig. 1A; Fig. S1). We hypothesized that this cDNA clone was derived from 5’ exon(s) of the primary transcript of the miR-183/96/182 gene, as CpG islands are often associated with promoters (2). Supporting this hypothesis, multiple expressed sequences detected by gene-trap clones, including clone D016D06 (3, 4), were co-localized with the cDNA clone AK044220 (Fig. 1A; Fig. S1). Clone D016D06, deposited by the German GeneTrap Consortium (GGTC) (http://tikus.gsf.de) (3, 4), was derived from insertion of a retroviral construct, rFlpROSAβgeo in 129S2 ES cells (Fig. 1A and C). The rFlpROSAβgeo construct carries a promoterless reporter gene, the β−geo cassette - an in-frame fusion of the β-galactosidase and neomycin resistance (Neor) gene (5), with a splicing acceptor (SA) immediately upstream, and a polyA signal downstream of the β−geo cassette (Fig.
    [Show full text]
  • 9-Azido Analogs of Three Sialic Acid Forms for Metabolic Remodeling Of
    Supporting Information 9-Azido Analogs of Three Sialic Acid Forms for Metabolic Remodeling of Cell-Surface Sialoglycans Bo Cheng,†,‡ Lu Dong,†,§ Yuntao Zhu,†,‡ Rongbing Huang,†,‡ Yuting Sun,†,‖ Qiancheng You,†,‡ Qitao Song,†,§ James C. Paton, ∇ Adrienne W. Paton,∇ and Xing Chen*,†,‡,§,⊥,# †College of Chemistry and Molecular Engineering, ‡Beijing National Laboratory for Molecular Sciences, §Peking−Tsinghua Center for Life Sciences,‖Academy for Advanced Interdisciplinary Studies, ⊥Synthetic and Functional Biomolecules Center, and #Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Peking University, Beijing 100871, China ∇Research Centre for Infectious Diseases, Department of Molecular and Biomedical Science, University of Adelaide, Adelaide SA 5005, Australia Page S1 Table of Contents: Scheme S1.……………………………………………………….........……………. S3 Figure S1……………………………………………………..………..……………. S3 Figure S2……………………………………………………..………..…………… S4 Figure S3……………………………………………………..………..…………… S4 Figure S4……………………………………………………..………..…………… S5 Figure S5……………………………………………………..………..…………… S6 Figure S6……………………………………………………..………..…………….S7 Figure S7……………………………………………………..………..…………….S8 Figure S8……………………………………………………..………..…………….S9 Experimental Procedures……………………………….…........…………....S10-S27 Table S1………………………………………………..………..…………….S28-S48 Supporting Reference……………………………………………….......………...S49 Page S2 Scheme S1. Synthesis of 9AzNeu5Gc Figure S1: a, b, c, d) Representative scatter plots (FSC vs. SSC) and histograms of flow cytometry analysis
    [Show full text]
  • Dataset for the Quantitative Proteomics Analysis of the Primary Hepatocellular Carcinoma with Single and Multiple Lesions
    Data in Brief 5 (2015) 226–240 Contents lists available at ScienceDirect Data in Brief journal homepage: www.elsevier.com/locate/dib Data Article Dataset for the quantitative proteomics analysis of the primary hepatocellular carcinoma with single and multiple lesions Xiaohua Xing a,b, Yao Huang c, Sen Wang a,b, Minhui Chi a,b,c, Yongyi Zeng a,b,c, Lihong Chen a,b,c, Ling Li a,b,c, Jinhua Zeng a,b,c, Minjie Lin a,b, Xiao Han d, Jingfeng Liu a,b,c, Xiaolong Liu a,b,n a The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People’s Republic of China b The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People’s Republic of China c Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People’s Republic of China d Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, People’s Republic of China article info abstract Article history: Hepatocellular Carcinoma (HCC) is one of the most common malig- Received 18 August 2015 nant tumor, which is causing the second leading cancer-related death Received in revised form worldwide. The tumor tissues and the adjacent noncancerous tissues 27 August 2015 obtained from HCC patients with single and multiple lesions were Accepted 28 August 2015 quantified using iTRAQ. A total of 5513 proteins (FDR of 1%) were Available online 8 September 2015 identified which correspond to roughly 27% of the total liver proteome.
    [Show full text]
  • Transcriptome Profiling Revealed Potentially
    Wang et al. BMC Genomics (2020) 21:546 https://doi.org/10.1186/s12864-020-06950-y RESEARCH ARTICLE Open Access Transcriptome profiling revealed potentially important roles of defensive gene expression in the divergence of insect biotypes: a case study with the cereal aphid Sitobion avenae Da Wang1,2, Deguang Liu1,2* , Xiaoqin Shi1,2, Yujing Yang1,2, Na Zhang1,2 and Zheming Shang1,2 Abstract Background: Many insects can develop differential biotypes on variable host plants, but the underlying molecular factors and mechanisms are not well understood. To address this issue, transcriptome profiling analyses were conducted for two biotypes of the cereal aphid, Sitobion avenae (Fabricius), on both original and alternative plants. Results: Comparisons between both biotypes generated 4174 differentially expressed unigenes (DEGs). In their response to host plant shift, 39 DEGs were shared by both biotypes, whereas 126 and 861 DEGs occurred only in biotypes 1 and 3, respectively. MMC (modulated modularity clustering) analyses showed that specific DEGs of biotypes 1 and 3 clustered into five and nine transcriptional modules, respectively. Among these DEGs, defense- related genes underwent intensive expression restructuring in both biotypes. However, biotype 3 was found to have relatively lower gene transcriptional plasticity than biotype 1. Gene enrichment analyses of the abovementioned modules showed functional divergence in defensive DEGs for the two biotypes in response to host transfer. The expression plasticity for some defense related genes was showed to be directly related to fecundity of S. avenae biotypes on both original and alternative plants, suggesting that expression plasticity of key defensive genes could have significant impacts on the adaptive potential and differentiation of S.
    [Show full text]
  • The Effect of Acid on the Dynamics of Intracellular Zinc and the Marker Expressions Of
    The Effect of Acid on the Dynamics of Intracellular Zinc and the Marker Expressions of Pluripotency in Somatic Cells A thesis presented to the faculty of the College of Arts and Sciences of Ohio University In partial fulfillment of the requirements for the degree Master of Science Yuli Hu April 2021 © 2021 Yuli Hu. All Rights Reserved. 2 This thesis titled The Effect of Acid on the Dynamics of Intracellular Zinc and the Marker Expressions of Pluripotency in Somatic Cells by YULI HU has been approved for the Department of Biological Sciences and the College of Arts and Sciences by Yang V. Li Professor of Biomedical Sciences Florenz Plassmann Dean, College of Arts and Sciences 3 Abstract YULI HU, M.S., April 2021, Biological Sciences The Effect of Acid on the Dynamics of Intracellular Zinc and the Marker Expressions of Pluripotency in Somatic Cells Director of Thesis: Yang V. Li Microenvironmental pH is one of the factors that affect the stability of zinc- protein binding. The tight binding between zinc and proteins is favored by the basic pH, whereas acidic pH favors a loose bound, and treatment of strong acid results in the dissociation of zinc. Physiologically, the stomach uses a very acidic pH to digest food which results in a high amount of soluble zinc in the stomach. Whether or not zinc co- present with acid and the effect of zinc on the gastric lining has rarely been discussed. In my experiments, acidic treatment induced the expression of a pluripotent marker in primary cultured gastric cells. It also stimulated the release of intracellular zinc, suggesting that acidic pH supported protein expression through dynamic zinc regulation.
    [Show full text]
  • Effects of a Bacterial ACC Deaminase on Plant Growth
    Effects of a bacterial ACC deaminase on plant growth-promotion by Jennifer Claire Czarny A thesis presented to the University of Waterloo in fulfilment of the thesis requirement for the degree of Doctor of Philosophy in Biology Waterloo Ontario, Canada, 2008 c Jennifer Claire Czarny 2008 Author's declaration I hereby declare that I am the sole author of this thesis. This is a true copy of the thesis, including any required final revisions, as accepted by my examiners. I understand that my thesis may be made electronically available to the public. ii Abstract Plants often live in association with growth-promoting bacteria, which provide them with several benefits. One such benefit is the lowering of plant ethylene levels through the action of the bacterial enzyme 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase that cleaves the immediate biosynthetic precursor of ethylene, ACC. The plant hormone ethylene is responsible for many aspects of plant growth and development but under stressful conditions ethylene exacerbates stress symptoms. The ACC deaminase-containing bacterium Pseudomonas putida UW4, isolated from the rhizosphere of reeds, is a potent plant growth- promoting strain and as such was used, along with an ACC deaminase minus mutant of this strain, to study the role of ACC deaminase in plant growth-promotion. Also, transgenic plants expressing a bacterial ACC deaminase gene were used to study the role of this enzyme in plant growth and stress tolerance in the presence and absence of nickel. Transcriptional changes occurring within plant tissues were investigated with the use of an Arabidopsis oligonucleotide microarray. The results showed that transcription of genes involved in hormone regulation, secondary metabolism and the stress response changed in all treatments.
    [Show full text]
  • Frontiersin.Org 1 April 2015 | Volume 9 | Article 123 Saunders Et Al
    ORIGINAL RESEARCH published: 28 April 2015 doi: 10.3389/fnins.2015.00123 Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study Norman R. Saunders 1*, Katarzyna M. Dziegielewska 1, Kjeld Møllgård 2, Mark D. Habgood 1, Matthew J. Wakefield 3, Helen Lindsay 4, Nathalie Stratzielle 5, Jean-Francois Ghersi-Egea 5 and Shane A. Liddelow 1, 6 1 Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, VIC, Australia, 2 Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark, 3 Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia, 4 Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland, 5 Lyon Neuroscience Research Center, INSERM U1028, Centre National de la Recherche Scientifique UMR5292, Université Lyon 1, Lyon, France, 6 Department of Neurobiology, Stanford University, Stanford, CA, USA The transcriptome of embryonic and adult rat lateral ventricular choroid plexus, using a combination of RNA-Sequencing and microarray data, was analyzed by functional groups of influx transporters, particularly solute carrier (SLC) transporters. RNA-Seq Edited by: Joana A. Palha, was performed at embryonic day (E) 15 and adult with additional data obtained at University of Minho, Portugal intermediate ages from microarray analysis. The largest represented functional group Reviewed by: in the embryo was amino acid transporters (twelve) with expression levels 2–98 times Fernanda Marques, University of Minho, Portugal greater than in the adult. In contrast, in the adult only six amino acid transporters Hanspeter Herzel, were up-regulated compared to the embryo and at more modest enrichment levels Humboldt University, Germany (<5-fold enrichment above E15).
    [Show full text]
  • Supplemental Data
    Article TCF7L2 is a master regulator of insulin production and processing ZHOU, Yuedan, et al. Abstract Genome-wide association studies have revealed >60 loci associated with type 2 diabetes (T2D), but the underlying causal variants and functional mechanisms remain largely elusive. Although variants in TCF7L2 confer the strongest risk of T2D among common variants by presumed effects on islet function, the molecular mechanisms are not yet well understood. Using RNA-sequencing, we have identified a TCF7L2-regulated transcriptional network responsible for its effect on insulin secretion in rodent and human pancreatic islets. ISL1 is a primary target of TCF7L2 and regulates proinsulin production and processing via MAFA, PDX1, NKX6.1, PCSK1, PCSK2 and SLC30A8, thereby providing evidence for a coordinated regulation of insulin production and processing. The risk T-allele of rs7903146 was associated with increased TCF7L2 expression, and decreased insulin content and secretion. Using gene expression profiles of 66 human pancreatic islets donors', we also show that the identified TCF7L2-ISL1 transcriptional network is regulated in a genotype-dependent manner. Taken together, these results demonstrate that not only synthesis of [...] Reference ZHOU, Yuedan, et al. TCF7L2 is a master regulator of insulin production and processing. Human Molecular Genetics, 2014, vol. 23, no. 24, p. 6419-6431 DOI : 10.1093/hmg/ddu359 PMID : 25015099 Available at: http://archive-ouverte.unige.ch/unige:45177 Disclaimer: layout of this document may differ from the published
    [Show full text]
  • Advances and Perspectives in Prostate Cancer Biomarker Discovery in the Last 5 Years Through Tissue and Urine Metabolomics
    H OH metabolites OH Review Advances and Perspectives in Prostate Cancer Biomarker Discovery in the Last 5 Years through Tissue and Urine Metabolomics Ana Rita Lima 1,* , Joana Pinto 1 , Filipa Amaro 1, Maria de Lourdes Bastos 1,Márcia Carvalho 1,2,3,* and Paula Guedes de Pinho 1,* 1 UCIBIO/REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal; [email protected] (J.P.); [email protected] (F.A.); [email protected] (M.d.L.B.) 2 UFP Energy, Environment and Health Research Unit (FP-ENAS), University Fernando Pessoa, Praça Nove de Abril, 349, 4249-004 Porto, Portugal 3 Faculty of Health Sciences, University Fernando Pessoa, Rua Carlos da Maia, 296, 4200-150 Porto, Portugal * Correspondence: [email protected] (A.R.L.); [email protected] (M.C.); [email protected] (P.G.d.P.); Tel.: +351-220-428-500 (A.R.L. & P.G.d.P.); +351-225-071-300 (M.C.) Abstract: Prostate cancer (PCa) is the second most diagnosed cancer in men worldwide. For its screening, serum prostate specific antigen (PSA) test has been largely performed over the past decade, despite its lack of accuracy and inability to distinguish indolent from aggressive disease. Metabolomics has been widely applied in cancer biomarker discovery due to the well-known metabolic reprogramming characteristic of cancer cells. Most of the metabolomic studies have Citation: Lima, A.R.; Pinto, J.; reported alterations in urine of PCa patients due its noninvasive collection, but the analysis of prostate Amaro, F.; Bastos, M.d.L.; Carvalho, tissue metabolome is an ideal approach to disclose specific modifications in PCa development.
    [Show full text]
  • Number 3 March 2012
    VolumeVolume 16 1 -- NumberNumber 31 May March- Sept ember2012 1997 Atlas of Genetics and Cytogenetics in Oncology and Haematology OPEN ACCESS JOURNAL AT INIST-CNRS Scope The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a peer reviewed on-line journal in open access, devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases. It presents structured review articles ("cards") on genes, leukaemias, solid tumours, cancer-prone diseases, more traditional review articles on these and also on surrounding topics ("deep insights"), case reports in hematology, and educational items in the various related topics for students in Medicine and in Sciences. Editorial correspondance Jean-Loup Huret Genetics, Department of Medical Information, University Hospital F-86021 Poitiers, France tel +33 5 49 44 45 46 or +33 5 49 45 47 67 [email protected] or [email protected] Staff Mohammad Ahmad, Mélanie Arsaban, Marie-Christine Jacquemot-Perbal, Maureen Labarussias, Vanessa Le Berre, Anne Malo, Catherine Morel-Pair, Laurent Rassinoux, Alain Zasadzinski. Philippe Dessen is the Database Director, and Alain Bernheim the Chairman of the on-line version (Gustave Roussy Institute – Villejuif – France). The Atlas of Genetics and Cytogenetics in Oncology and Haematology (ISSN 1768-3262) is published 12 times a year by ARMGHM, a non profit organisation, and by the INstitute for Scientific and Technical Information of the French National Center for Scientific Research (INIST-CNRS) since 2008. The Atlas is hosted by INIST-CNRS (http://www.inist.fr) http://AtlasGeneticsOncology.org © ATLAS - ISSN 1768-3262 The PDF version of the Atlas of Genetics and Cytogenetics in Oncology and Haematology is a reissue of the original articles published in collaboration with the Institute for Scientific and Technical Information (INstitut de l’Information Scientifique et Technique - INIST) of the French National Center for Scientific Research (CNRS) on its electronic publishing platform I-Revues.
    [Show full text]
  • Mirnas Documented to Play a Role in Hematopoietic Cell Lineage. Our
    Table S1: miRNAs documented to play a role in hematopoietic cell lineage. Our review of the literature summarizing miRNAs known to be involved in the development and proliferation of the hematopoietic lineage cells. miRNA Expression/function/target/regulator References miR-150 Elevated during developmental stages of B and T cell maturation. 16-19 Controls B cell differentiation, present in mature, resting T and B cells but decreased upon activation of naïve T or B cells. Plays a role in establishing lymphocyte identity. Very little is known about function in T cells. Regulators: Foxp3 Target: C-Myb miR-146a/b Upregulated in macropgahe inflammatory response. Differentially 17, 20 upregulated in murine Th1 subset but abolished in Th2 subset. Upregulated in response to TCRs stimulation, as well as by IL-1 and TNF. Highly expressed in murine T-regs and could play a role in establishing lymphocyte identity. Modulates activation induced cell death in activated T cells. Negative regulator of TLR and cytokine signaling pathway. Endotoxin tolerance. Antiviral role. Targets: IRAK1, IRAK2, TRAF6, FAF1 miR-16-1 Promote apoptosis by targeting Bcl2 expression, act as tumor 22 cluster suppressor RNAs. May block differentiation of later stage hematopoietic progenitor cells to mature cells. Downregulated in CLL. Target: BCL2. miR-155 Regulator of T and B cell maturation and innate immune response. 23-29 Expressed in primary mediastinal B-cell lymphoma, T and B cells, macrophages and DCs. Upregulated during B cell activation. Involved in T cell differentiation and indicated as a positive regulator of cytokine production. Activated by stimulating TLR3 and INFab receptors in bone derived macrophages (regulation of antimicrobial defense).
    [Show full text]
  • Overexpression of the Transporters Atzip1 and Atmtp1 in Cassava Changes Zinc Accumulation and Partitioning
    ORIGINAL RESEARCH published: 09 July 2015 doi: 10.3389/fpls.2015.00492 Overexpression of the transporters AtZIP1 and AtMTP1 in cassava changes zinc accumulation and partitioning Eliana Gaitán-Solís1,NigelJ.Taylor1, Dimuth Siritunga2, William Stevens3 and Daniel P. Schachtman4* 1 Donald Danforth Plant Science Center, St Louis, MO, USA, 2 University of Puerto Rico Mayagüez, Mayagüez, PR, USA, 3 University of Missouri Delta Center, Portageville, MO, USA, 4 Department of Agronomy and Horticulture, University of Nebraska Lincoln, Lincoln, NE, USA Zinc deficiency in humans is a serious problem worldwide with an estimated one third of populations at risk for insufficient zinc in diet, which leads to impairment of cognitive abilities and immune system function. The goal of this research was to Edited by: increase the bioavailable zinc in the edible portion of cassava roots to improve the Soren K. Rasmussen, overall zinc nutrition of populations that rely on cassava as a dietary staple. To increase University of Copenhagen, Denmark zinc concentrations, two Arabidopsis thaliana genes coding for ZIP1 and MTP1 were Reviewed by: overexpressed with a tuber-specific or constitutive promoter. Eighteen transgenic events Peter Gresshoff, The University of Queensland, from four constructs, out of a total of 73 events generated, showed significantly higher Australia zinc concentrations in the edible portion of the storage root compared to the non- John Beeching, transgenic controls. The zinc content in the transgenic lines ranged from 4 to 73 University of Bath, UK *Correspondence: mg/kg dry weight (DW) as compared to the non-transgenic control which contained Daniel P. Schachtman, 8 mg/kg.
    [Show full text]