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Download Issue As Important note: Please share this digital-only edition of Almanac with your colleagues. Read more. UNIVERSITY OF PENNSYLVANIA Tuesday December 15, 2020 Volume 67 Number 22 www.upenn.edu/almanac Penn Medicine’s Collaboration with Kimberly Kessler Ferzan: Two New Endowed Chair Regeneron on COVID-19 Earle Hepburn Professor of Law Appointments in Nursing Antibody Cocktail and Co-Director of the Institute of Tanja Kral has been named the Ellen and A new University of Pennsylvania research Law & Philosophy Robert Kapito Endowed Professor in Nursing collaboration with Regeneron Pharmaceuticals, Kimberly Kessler Ferzan, L’95, has been Science and Jianghong Liu has been named Inc. will investigate whether Regeneron’s ca- named the Earle Hepburn Professor of Law the Marjorie O. Rendell Endowed Professor in sirivimab and imdevimab investigational antibody and Co-Director of the Institute of Law & Healthy Transitions, effective September 1, 2020. cocktail can prevent COVID-19 infection when Philosophy at Penn’s delivered intranasally via Adeno-Associated Vi- Carey Law School. rus (AAV) vectors. Regeneron’s antibody cock- She will teach Crimi- tail (casirivimab and imdevimab administered nal Law, Evidence, together) is being studied in clinical trials for the and a seminar on the treatment and prevention of COVID-19 and was theory and practice recently granted an Emergency Use Authoriza- of criminal law. She tion by the U.S. Food and Drug Administration is co-Editor-in-Chief (FDA) in certain high-risk patients with mild to of the journal Law moderate COVID-19. and Philosophy and Gene therapy pioneer James Wilson, profes- serves on the editorial sor of medicine and boards of Legal Theo- director of the Gene ry, Criminal Law and Therapy Program Philosophy, the Stan- and the Orphan Dis- ford Encyclopedia Kimberly Ferzan Tanja Kral Jianghong Liu ease Center at Penn’s of Philosophy, and Perelman School of Oxford Studies in Political Philosophy. She was Dr. Kral is professor of nutrition science and Medicine, and his elected to the American Law Institute in 2015. associate program director of the Graduate Nutri- team will work with Dr. Ferzan writes in criminal law theory. She tion Certificate, with a secondary appointment Regeneron to study has co-authored two books and co-edited three as professor in the department of psychiatry at the safety and ef- as well as authoring over 50 book chapters and the Perelman School of Medicine. One of many fectiveness of using articles. She received the American Philosophi- multi-disciplinary faculty in the Penn Nursing AAV vectors to intro- cal Association’s Berger Memorial Prize in 2013 family, she is a nutrition scientist with training duce the sequence of for “Beyond Crime and Commitment: Justifying in the study of human ingestive behavior. Her the cocktail’s virus- Liberty Deprivations of the Dangerous and Re- research focuses on the cognitive, sensory, and neutralizing antibod- James Wilson (continued on page 4) nutritional controls of appetite and eating in ies directly to nasal children and adults and their relevance to obe- epithelial cells. This new collaboration will sity. In predominantly minority children from introduce the application of AAVs, which have Karen Tani: Seaman Family low-resource environments, Dr. Kral studies traditionally been used for gene therapies against University Professor protective factors within families for mitigating deadly genetic diseases, to the fight against a Karen Tani, L’07 GR’11, is the Seaman behavioral and socioeconomic risk factors for virus that has infected more than 50 million Family University Professor and holds a joint obesity development. people across the globe and taken the lives of appointment with the Dr. Kral has a strong record of funding and 1.25 million to date. department of his- publication. Currently, she is chair of the PhD “The fight against COVID-19 requires the tory in the School of Progressions Committee and Chair-Elect of the most creative approaches for the prevention, Arts and Sciences. Graduate Group. She is the recipient of the Alan testing, and treatment of this disease,” Dr. Wilson She is the Univer- Epstein Research Award from the Society for the said. “Early clinical data from Regeneron show sity of Pennsylvania’s Study of Ingestive Behavior (SSIB), the execu- that their investigational antibody combination 24th Penn Integrates tive editor of Appetite journal; and recipient of may play a role in helping treat the disease and re- Knowledge Univer- the Dean’s Award for Undergraduate Scholarly duce severity in those who are infected. We hope sity Professor. Dr. Mentorship from Penn’s School of Nursing. She to leverage the virus-neutralizing ability of this Tani is co-teaching is an associate fellow of the Center for Public antibody cocktail for prevention of COVID-19 a 1L elective course Health Initiatives and a member of the Interdis- using a novel delivery mechanism, as well. on Law and Inequal- ciplinary Research Network. “The advantage of AAV in this application is ity with Presidential Dr. Liu is professor of nursing, co-director of that [it] can achieve sustained expression of the Assistant Professor (continued on page 4) Karen Tani antibodies in the nasal mucosa, which is the site of Law Shaun Ossei- INSIDE of infection, following a single administration,” Owusu. 2 Senate: SEC Actions and Resolution; Trustees he continued. “In contrast to traditional vaccines, A celebrated legal historian, Dr. Tani’s work 3 Deaths; Climate and Sustainability Action Plan 3.0 AAV delivery of antibodies provides a rapid onset addresses poverty law and policy, disability, 4 Penn Nursing’s Biobehavioral Health Sciences; New Collaboration on Digital Patient Education of response and no reliance on the need for the administrative law, federalism, and rights. Her 5 Marshall Scholars; Schwartzman Scholars recipient to mount an immune system response book, States of Dependency: Welfare, Rights, and 6 Medical Miracles on 34th Street over time. This latter feature may be particularly American Governance, 1935-1972 (Cambridge 8 January AT PENN Calendar attractive in people with weakened immune sys- University Press, 2016), won the 2017 Cromwell 10 Honors & Other Things 12 Penn’s Gargoyles: Genial Gothic Gremlins tems, like the elderly, or people who need rapid Book Prize from the American Society for Legal 14 HR: Upcoming Programs and Special Winter protection, like frontline healthcare workers.” History. The book sheds new light on the nature Vacation Hours; Public Safety: Property Checks One of Dr. Wilson’s major goals throughout of modern American governance by examining and Walking Escorts 15 Update; CrimeStats; Call for 2021 Summer Camps (continued on page 2) (continued on page 4) 16 After More Than 40 years, Almanac’s Dedicated Leader to Retire ALMANAC December 15, 2020 www.upenn.edu/almanac 1 SENATE From the Senate Office Trustees Executive Committee Meeting Coverage The Executive Committee of the Penn The following is published in accordance with the Faculty Senate Rules. Among other purposes, Board of Trustees met virtually on December the publication of SEC actions is intended to stimulate discussion among the constituencies and 10 for a brief Stated Meeting at which time a their representatives. Please communicate your comments to Patrick Walsh, executive assistant to resolution was passed to appoint Scott L. Bok the Senate Office, either by telephone at (215) 898-6943 or by email at [email protected] and Ann Reese to the Penn Medicine Board and the Penn Medicine Executive Committee. Scott L. Bok, a University Trustee, was ap- Faculty Senate Executive Committee Actions pointed to the Penn Medicine Board, for a three Wednesday, December 9, 2020 year term as Term Member, effective Novem- ber 13, 2020 until November 12, 2023, and was appointed to the Penn Medicine Executive Special Note: The Town Hall held on December 9, “From Campus Access to Testing Committee, effective November 13, 2020, to and Vaccination: What to Expect for Penn’s COVID-Era Spring Semester,” is available for serve in accordance with the Bylaws. viewing at https://provost.upenn.edu/senate/faculty-senate-seminar-series. Written responses Ann Reese, a University Trustee, was ap- to the remaining questions will also be available at the same page upon their finalization. pointed to the Penn Medicine Board, for a three year term as Term Member, effective January 1, 2021 until December 31, 2023, and be ap- pointed to the Penn Medicine Executive Com- Chair’s Report. Faculty Senate Chair Kathleen Hall Jamieson reminded Senate Executive Com- mittee, effective January 1, 2021, to serve in ac- mittee (SEC) members that Provost Wendell Pritchett will return to SEC in January 2021 and invited cordance with the Bylaws. questions for him to be submitted to the Senate Office. Senate Committees will also be invited to share questions. Provost Pritchett is prepared to discuss questions on the relationship between Penn and the surrounding community. Penn Medicine Collaboration On January 20 at 4 p.m. ET, SEC will also convene a virtual, interactive workshop on “Inter- with Regeneron rogating and Re-Imagining Expressive Public Space on the Penn Campus” during the second half (continued from page 1) of its meeting; this session will be open to all faculty members. his career has been to develop new methods for Past Chair’s Report. No report was offered. delivering genes to cells. He led his lab at the Resolution in Appreciation of Penn’s Contributions to Doctoral Education at Penn and GTP to discover the AAV family of viruses, to the School District of Philadelphia through the Penn Compact. Following a motion and found in primate tissues, that can be engineered discussion, SEC members voted unanimously to adopt the Resolution, which appears as an appendix to ferry healthy DNA into the correct cells. AAV to these minutes (see below). vectors—the most commonly used viral vectors today—were developed by Dr.
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