Life Sciences and Technology Company Listing: September 2020

Business Name Address City State

TCR2 Therapeutics 100 Binney Street Cambridge MA

Eikonizo Therapeutics 700 Main Street Cambridge MA

Lysosomal Therapeutics 19 Blackstone Street Cambridge MA

AOBiome 125 Cambridgepark Drive Cambridge MA

Nuance 675 Avenue Cambridge MA

Scholar Rock, LLC 620 Memorial Drive Cambridge MA

Vecna Technologies 36 Cambridge Park Drive Cambridge MA

Ironwood Pharmaceuticals 301 Binney Street Cambridge MA

Totient One Alewife Center Cambridge MA

Verily Cambridge MA

Navitor Pharmaceuticals 1030 Massachusetts Avenue Cambridge MA

WaveGuide Corporation 675 West Kendall Street Cambridge MA

Page 1 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Zip Code Business Type Business Class

02142 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02140 Biotechnology Life Science

02139 Information Technology High Tech

02139 Biopharmaceutical Life Science

02140 Information Technology Life Science

02142 Biopharmaceutical Life Science

02140 Biotechnology Life Science

Biotechnology Life Science

02139 Biopharmaceutical Life Science

02142 Biotechnology Life Science

Page 2 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Year Business Description Established

R&D in cancer treatment

Developing disease-modifying therapeutics for neurodegenerative diseases 2017

R&D in small-molecule research neurodegeneration diseases 2011

Development of microbiome-based therapies for inflammatory conditions 2013

Voice recognition software 1992

R&D in biologic therapies called niche activators 2012

High tech research in healthcare, business and robotics 1999

Drug development 1998

Immunoinformatics algorithms and machine learning 2017

Life Sciences company 2019

Pharmaceutical R&D 2014

Medical Device

Page 3 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Website Longitude Latitude Location

-71.0805992117041 42.3652581293824 (42.3652581293824, - http://www.tcr2.com/ 71.0805992117041) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.eikonizo.com/ 71.09491617478) -71.1145004232591 42.3634172936065 (42.3634172936065, - https://www.lysosomaltx.com/ 71.1145004232591) -71.1457538393149 42.3950752907362 (42.3950752907362, - https://www.aobiome.com/ 71.1457538393149) -71.1040820735933 42.3658127184955 (42.3658127184955, - http://www.nuance.com 71.1040820735933) -71.1076001591032 42.3539087777099 (42.3539087777099, - http://www.scholarrock.com/index.html 71.1076001591032) -71.1438261608321 42.3940100972981 (42.3940100972981, - http://www.vecna.com 71.1438261608321) -71.0879679450326 42.3665842178827 (42.3665842178827, - http://ironwoodpharma.com/ 71.0879679450326) -71.1399143502488 42.3983467196212 (42.3983467196212, - https://totient.bio/ 71.1399143502488)

https://verily.com/ -71.1122045152113 42.3695906454501 (42.3695906454501, - http://www.navitorpharma.com/ 71.1122045152113) -71.0819311032568 42.3646274397156 (42.3646274397156, - http://waveguidecorp.com/

Page 4 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Police Police cambridge_nei cambridge_cdd Census Blocks Neighborhood Response ghborhoods _zoning 2010 Regions Districts 4 79 8 253 89

7 83 1 258 86

13 82 5 196 412

6 3 13 168 1098

10 75 6 264 378

5 85 3 178 125

6 3 13 168 1105

4 71 8 117 310

6 2 13 166 1070

13 66 5 110 166

4 79 8 276 154

Page 5 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

BioAxone BioSciences, Inc. 763 Concord Ave Cambridge MA

Sarepta Therapeutics 215 First Street Cambridge MA

Catabasis Pharmaceuticals One Cambridge MA

Takeda Pharmaceutical Company 300 Massachusetts Ave. Cambridge MA

Broad Institute 415 Main Street Cambridge MA

Enzyvant 55 Cambridge Parkway Cambridge MA

Ariana Data Intelligence, Inc. One Broadway Cambridge MA

SeromYx Systems 99 Erie Street Cambridge MA

Vedantra Pharmaceuticals One Kendall Square Cambridge MA

Google, Inc. 355 Main Street Cambridge MA

Octagon Therapeutics 700 Main Street Cambridge MA

Vigeo Therapeutics 86 Sherman Street Cambridge MA

Page 6 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02138 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02142 Academic/Nonprofit R&D Academic/Non-Profit

02142 Biopharmaceutical Life Science

02142 Bioinformatics Life Science

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Information Technology High Tech

02139 Biotechnology Life Science

02140 Biotechnology Life Science

Page 7 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

R&D in regenerative medicine

R&D in RNA-based therapeutics 1980

R&D in inflammatory conditions 2009

Biopharmaceutical R&D 1781

Academic Research Institution 2004

Drug Development

Clinical and biomarker data analytics technology 2002

Drug development 2019

R&D in ICMVs 2013

Web/Application Development 1998

Drug development 2017

Cancer therapeutics company 2011

Page 8 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

71.0819311032568) http://waveguidecorp.com/ -71.1526217445868 42.3927176062605 (42.3927176062605, - http://bioaxonebio.com/ 71.1526217445868) -71.0785437379441 42.3642063517586 (42.3642063517586, - https://www.sarepta.com/ 71.0785437379441) -71.0903221519948 42.3672909799538 (42.3672909799538, - http://www.catabasis.com/ 71.0903221519948) -71.0988575448498 42.3622760776956 (42.3622760776956, - https://www.takeda.com/en-us/ 71.0988575448498) -71.0891226713898 42.3628674386568 (42.3628674386568, - http://www.broadinstitute.org/ 71.0891226713898) -71.0762977105578 42.3657420050532 (42.3657420050532, - https://enzyvant.com/contact-us/ 71.0762977105578) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.arianapharma.com/ 71.0838266372968) -71.1055206894536 42.3588440982339 (42.3588440982339, - http://www.seromyx.com/ 71.1055206894536) -71.0903221519948 42.3672909799538 (42.3672909799538, - http://vedantra.com/ 71.0903221519948) -71.087115791042 42.3626348636581 (42.3626348636581, - http://www.google.com 71.087115791042) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.octagontherapeutics.com/ 71.09491617478) -71.1322809196099 42.3883177011679 (42.3883177011679, - https://vigeotherapeutics.com/ 71.1322809196099)

Page 9 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

1 8 10 289 1066

4 79 8 276 318

3 73 7 258 68

11 116 4 265 128

5 88 3 279 255

4 65 8 218 153

4 79 8 277 295

11 117 4 151 184

3 73 7 258 68

5 88 3 280 145

7 83 1 258 86

8 97 2 20 868

Page 10 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Casma Therapeutics 400 Technology Square Cambridge MA

nQ Medical 245 Main Street Cambridge MA

BioExec Institute One Broadway Cambridge MA

Rgenta Therapeutics 700 Main Street Cambridge MA

Rekindle Therapeutics 700 Main Street Cambridge MA

IntegraGen 1 Mifflin Place, Suite 400 Cambridge MA

CarGurus 2 Canal Park Cambridge MA

Baxalta 650 East Kendall St Cambridge MA

Seres Therapeutics 200 Sidney Street Cambridge MA

VBI Vaccines 222 Third Street Cambridge MA

IBM Research Center 75 Binney Street Cambridge MA

Boston Oncology 245 First Street Cambridge MA

Summit Therapeutics One Broadway Cambridge MA

Page 11 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02138 Biotechnology Life Science

02141 Information Technology High Tech

02142 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02141 Biotechnology Life Science

02142 Information Technology High Tech

02142 Biotechnology Life Science

02142 Biotechnology Life Science

Page 12 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Drug development based on autophagy 2018

Neurotechnology company 2016

Life sciences leadership network

Develops RNA-targeting medicines 2018

Molecular Genetics Research

Online service for evaluating cars

Drug Development 1931

Biotherapeutic company developing ecobiotic products 2010

Vaccine development in infectious diseases 2001

Software/Application Development 2008

Chemotherapeutic and biotechnology therapy development 2005

R&D in innovative therapies

Page 13 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.091951377916 42.3638464323303 (42.3638464323303, - https://www.casmatx.com/ 71.091951377916) -71.0848274465445 42.362543834575 (42.362543834575, - http://www.nq-medical.com/ 71.0848274465445) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.bioexecinstitute.com/ 71.0838266372968) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.rgentatx.com/ 71.09491617478) -71.09491617478 42.3619392706752 (42.3619392706752, - 71.09491617478) -71.1224787776923 42.3732988725555 (42.3732988725555, - https://www.integragen.com/contact/offic 71.1224787776923) e-locations - 42.3700645210408 (42.3700645210408, - http://www.cargurus.com 71.0763151655322 9 71.07631516553229) -71.0810729236616 42.3645257329026 (42.3645257329026, - http://www.baxalta.com/index.page 71.0810729236616) -71.1048489587854 42.3581969319501 (42.3581969319501, - http://www.serestherapeutics.com/ 71.1048489587854) -71.0809909801686 42.3670782746947 (42.3670782746947, - http://vbivaccines.com 71.0809909801686) -71.0805066509211 42.3657792656652 (42.3657792656652, - http://www.watson.ibm.com/cambridge/i 71.0805066509211) ndex.shtml -71.0787234936367 42.3635391601232 (42.3635391601232, - http://bostononcology.com/ 71.0787234936367) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.summitplc.com/

Page 14 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

7 87 1 258 217

5 88 3 280 145

4 79 8 277 295

7 83 1 258 86

7 83 1 258 86

12 103 12 197 531

4 65 8 226 19

4 79 8 276 154

11 114 4 147 481

4 71 8 117 33

4 71 8 254 144

4 79 8 276 154

4 79 8 277 295

Page 15 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Infinity Pharmaceuticals, Inc. 784 Memorial Drive Cambridge MA

FUJIFILM Pharmaceuticals USA One Broadway Cambridge MA

EyeNetra 47 Third Street Cambridge MA

E25Bio 501 Massachusetts Avenue Cambridge MA

Inari One Kendall Square Cambridge MA

Daktari Diagnostics 85 Bolton Street Cambridge MA

Q32 Bio One Broadway Cambridge MA

GO Therapeutics One Broadway Cambridge MA

Celsius Therapeutics 399 Binney Street Cambridge MA

Tenza 700 Main Street Cambridge MA

Optum Labs One Main Street Cambridge MA

ChemAxon One Broadway Cambridge MA

Page 16 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02139 Biopharmaceutical Life Science

02142 Biopharmaceutical Life Science

02141 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02140 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Incubator Life Science

02142 Biotechnology Life Science

Page 17 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

R&D in cancer drug development 2001

Clinical Development

Developing mobile phone eye diagnostics 2011

Develops Rapid Diagnostic Tests for fever infectious diseases 2018

Agricultural biotechnology

Develop and delivery critical diagnostic test results

Developing treatment for autoimmune and inflammatory diseases

Cancer immunotherapy 2014

Drug development 2018

Drug delivery

R&D innovation center for the health care industry 2013

Chemical software development 1998

Page 18 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

71.0838266372968) http://www.summitplc.com/ -71.1150858508757 42.3597230355907 (42.3597230355907, - http://www.infi.com/ 71.1150858508757) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.fujifilmusa.com/about/corpor 71.0838266372968) ate_profile/fujifilm_companies/pharmace uticals/about/index.html -71.0800210116779 42.3713099001707 (42.3713099001707, - https://eyenetra.com/ 71.0800210116779) -71.1014931241571 42.3642623755098 (42.3642623755098, - http://www.e25bio.com/ 71.1014931241571) -71.0902561602224 42.3669114403858 (42.3669114403858, - http://www.inari.com/ 71.0902561602224) -71.1305699529474 42.39003115429 (42.39003115429, - http://www.daktaridx.com/ 71.1305699529474) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://www.q32bio.com/ 71.0838266372968) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.gotherapeutics.com/ 71.0838266372968) -71.0902337857325 42.3676019682682 (42.3676019682682, - http://www.celsiustx.com 71.0902337857325) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.tenza.bio/ 71.09491617478) -71.0801548712499 42.3621050405824 (42.3621050405824, - http://www.optum.com/Optumlabs 71.0801548712499) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://chemaxon.com

Page 19 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

11 20 4 243 42

4 79 8 277 295

4 57 8 186 635

7 80 1 264 22

3 73 7 258 68

8 97 2 16 727

4 79 8 277 295

4 79 8 277 295

3 61 7 117 723

7 83 1 258 86

4 79 8 276 272

4 79 8 277 295

Page 20 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

AuxoCell Laboratories 245 First Street Cambridge MA

Lab Central 700 Main Street Cambridge MA

ITeos Therapeutics 139 Main Street Cambridge MA

Cambridge Health Alliance 1493 Cambridge Street Cambridge MA

SmartPharm Therapeutics 650 East Kendall Street Cambridge MA

Angiex 700 Main Street Cambridge MA

Satorius Stedim North America, Inc. 245 First Street Cambridge MA

Rational Vaccines 21 Erie Street Cambridge MA

Forsyth Institute 245 First Street Cambridge MA

Enterome Bioscience One Broadway Cambridge MA

Vesigen Therapeutics 790 Memorial Drive Cambridge MA

XtalPi One Broadway Cambridge MA

Page 21 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Biopharmaceutical Life Science

02139 Incubator Coworking Space/Incubator 02142 Biotechnology Life Science

02139 Non-Profit Life Science

02142 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02142 Contract Research Life Science

02139 Biotechnology Life Science

02142 Research Institute Academic/Non-Profit

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biotechnology High Tech

Page 22 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Stem Cell Laboratory 2008

Lab Incubator Space 2013

Tumor immunology, cancer immunotherapy, and drug discovery 2011

Hospital 1996

Gene therapy 2017

R&D in cancer

Contract testing

Develops live-attenuated herpes simplex virus vaccines 2015

R&D in Oral Medicine 1910

R&D in Human Gut Microbiome

Drug delivery

Artificial intelligence, drug development 2014

Page 23 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

71.0838266372968)

-71.0787234936367 42.3635391601232 (42.3635391601232, - http://www.auxocell.com 71.0787234936367) -71.09491617478 42.3619392706752 (42.3619392706752, - http://www.labcentral.org/ 71.09491617478) -71.0822616219526 42.3622223616064 (42.3622223616064, - https://iteostherapeutics.com 71.0822616219526) -71.1044363345297 42.3744167811923 (42.3744167811923, - http://www.challiance.org/Main/Home.as 71.1044363345297) px -71.0810729236616 42.3645257329026 (42.3645257329026, - https://smartpharmtx.com/ 71.0810729236616) -71.09491617478 42.3619392706752 (42.3619392706752, - http://angiex.com/ 71.09491617478) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://www.biooutsource.com/ 71.0787234936367) -71.1038053210519 42.3578097131557 (42.3578097131557, - https://rationalvaccines.com/ 71.1038053210519) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://www.forsyth.org 71.0787234936367) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.enterome.fr/ 71.0838266372968) -71.1148317990337 42.3598764519961 (42.3598764519961, - https://www.vesigentx.com/ 71.1148317990337) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.xtalpi.com/ 71.0838266372968)

Page 24 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

4 79 8 276 154

7 83 1 258 86

4 79 8 276 295

10 43 6 69 589

4 79 8 276 154

7 83 1 258 86

4 79 8 276 154

11 117 4 147 124

4 79 8 276 154

4 79 8 277 295

11 20 4 243 42

4 79 8 277 295

Page 25 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Cambridge Biomedical Careers Program 1035 Cambridge Street Cambridge MA

Blueprint Medicines 45 Sidney Street Cambridge MA

Jounce Therapeutics 780 Memorial Drive Cambridge MA

Casebia Therapeutics 610 Main Street Cambridge MA

Synlife Bio One Kendall Square Cambridge MA

Massachusetts Biotechnology Council 300 Technology Square Cambridge MA

Vaxxas 47 Thorndike St Cambridge MA

Claritas Genomics 99 Erie Street Cambridge MA

Pykus Therapeutics One Mifflin Place Cambridge MA

Forrester Research 60 Acorn Park Drive Cambridge MA

Semma Therapeutics 100 Technology Square Cambridge MA

Intellia Therapeutics 40 Erie Street Cambridge MA

MediSapiens One Broadway Cambridge MA

Page 26 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02141 Non-Profit Academic/Non-Profit

02139 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02142 Non-Profit Academic/Non-Profit

02141 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02138 Medical Devices Life Science

02140 Information Technology High Tech

02142 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02142 Information Technology/Healthcare Life Science

Page 27 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Workforce Development

Drug Development 2011

R&D of cancer immunotherapies 2013

Novel CRISPr -based therapies 2016

Research Products and Instrumentation 2017

Non-profit, Workforce Development 2001

R&D in the next generation of vaccines 2011

Genetic diagnostic laboratory

Developer of surgical device for retinal surgery

Research Company 1983

R&D in Type 1 diabetes 2015

Development of CRISPR/Cas9 gene editing 2014

Genomics data software for biopharmaceutical companies 2009

Page 28 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0937041519439 42.3734936331323 (42.3734936331323, - http://www.justastart.org/ 71.0937041519439) -71.1014233914707 42.3619155589271 (42.3619155589271, - http://www.blueprintmedicines.com 71.1014233914707) -71.1147971377611 42.359586309195 (42.359586309195, - http://www.jouncetx.com/ 71.1147971377611) -71.0940133114707 42.3628809096634 (42.3628809096634, - http://www.casebia.com/ 71.0940133114707) -71.0911051057089 42.3663645885345 (42.3663645885345, - https://www.synlifebio.com/ 71.0911051057089) -71.0917711454075 42.3634083285031 (42.3634083285031, - http://www.massbio.org/ 71.0917711454075) -71.0795405331677 42.3698974797414 (42.3698974797414, - http://www.vaxxas.com/home 71.0795405331677) -71.1055206894536 42.3588440982339 (42.3588440982339, - http://claritasgenomics.com 71.1055206894536) -71.1224787776923 42.3732988725555 (42.3732988725555, - https://pykustherapeutics.com/ 71.1224787776923) -71.1487488532359 42.3982519281572 (42.3982519281572, - http://www.forrester.com/home 71.1487488532359) -71.0907938787327 42.3629489687522 (42.3629489687522, - http://www.semma-tx.com/ 71.0907938787327) -71.1042275993795 42.3574194822637 (42.3574194822637, - http://intelliatx.com/ 71.1042275993795) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.medisapiens.com/ 71.0838266372968)

Page 29 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

3 48 7 191 900

11 117 4 265 182

11 20 4 243 42

7 83 1 258 299

3 73 7 258 68

7 87 1 258 217

4 57 8 187 31

11 117 4 151 184

12 103 12 197 531

6 3 13 3 1010

7 87 1 258 398

11 114 4 147 481

4 79 8 277 295

Page 30 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Cove 295 Third Street Cambridge MA

NGIN Workplace 210 Broadway Cambridge MA

Aegerion Pharmaceuticals 245 First Street Cambridge MA

Ra Pharmaceuticals 87 CambridgePark Drive Cambridge MA

ViThera One Kendall Square Cambridge MA

Mercy Bioanalytics 700 Main Street Cambridge MA

Repertoire Immune Medecines 26 Landsdowne Street Cambridge MA

Vizgen 37 Spinelli Place Cambridge MA

24M Technologies 130 Brookline Street Cambridge MA

Cygnal Therapeutics 325 Vassar Street Cambridge MA

Solid Biosciences 141 Broadway Cambridge MA

Spero Therapeutics 675 Massachusetts Avenue Cambridge MA

Manus Bio 1030 Massachusetts Ave Cambridge MA

Page 31 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Coworking Space Coworking Space/Incubator 02139 Coworking Space Coworking Space/Incubator 02142 Biopharmaceutical Life Science

02140 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02138 Biotechnology Life Science

02139 Clean Technology Clean Energy

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02139 Biotechnology Life Science

Page 32 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Coworking Office Space

Flexible coworking space 2014

Drug Development in genetic disorders 2005

R&D 2008

Contract research organization 2009

Developing a liquid biopsy 2018

Designing immune medicines

Developing transcriptomics technologies 2019

Electric Energy R&D 2010

Drug development 2017

Focused on Duchenne Muscular Dystrophy 2014

Novel treatments for bacteria infections

Agricultural biotechnology

Page 33 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0833792914583 42.3644187617896 (42.3644187617896, - https://cove.is/ 71.0833792914583) -71.0932182826967 42.3661132632655 (42.3661132632655, - http://www.nginworkplace.com/ 71.0932182826967) -71.0787234936367 42.3635391601232 (42.3635391601232, - https://www.novelion.com/contact 71.0787234936367) -71.1447354193478 42.3954676435594 (42.3954676435594, - http://www.rapharma.com/ 71.1447354193478) -71.0902561602224 42.3669114403858 (42.3669114403858, - http://www.vitherapharma.com/ 71.0902561602224) -71.09491617478 42.3619392706752 (42.3619392706752, - https://mercybio.com/ 71.09491617478) -71.0990223853639 42.3610129940534 (42.3610129940534, - https://www.repertoire.com/ 71.0990223853639) -71.1537133050666 42.3922967326194 (42.3922967326194, - https://vizgen.com/ 71.1537133050666) -71.1046390137608 42.3603907075727 (42.3603907075727, - http://www.24mtechnologies.com 71.1046390137608) -71.1056951550591 42.3549339189278 (42.3549339189278, - http://www.cygnaltx.com/ 71.1056951550591) -71.0885041535868 42.3647572806653 (42.3647572806653, - http://solidbio.com/ 71.0885041535868) -71.1040820735933 42.3658127184955 (42.3658127184955, - https://sperotherapeutics.com/ 71.1040820735933) -71.1122045152113 42.3695906454501 (42.3695906454501, - http://www.manusbio.com 71.1122045152113)

Page 34 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

4 79 8 281 88

7 77 1 130 63

4 79 8 276 154

6 3 13 168 1098

3 73 7 258 68

7 83 1 258 86

11 117 4 265 239

1 8 10 289 1066

11 117 4 146 472

5 85 3 160 125

4 79 8 279 311

10 75 6 264 378

13 66 5 110 166

Page 35 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

3DBioLabs 700 Main Street Cambridge MA

Unum Therapeutics 200 Cambridge Park Drive Cambridge MA

Cydan Development 700 Technology Square Cambridge MA

Harvard-MIT Division of Health Sciences Technology 77 Massachusetts Ave Bldg. E25-519 Cambridge MA

Amber Biology 10 Appleton Road Cambridge MA

ALS Therapy Development Institute 300 Technology Square Cambridge MA

Oncorus 50 Hampshire Street Cambridge MA

Idera Pharmaceuticals, Inc. 167 Sidney Street Cambridge MA

Merrimack Pharmaceuticals, Inc. One Kendall Square Cambridge MA

Obsidian Therapeutics 1030 Massachusetts Avenue Cambridge MA

Renewable Energy Massachusetts 17 Arlington Street Cambridge MA

Thrombolytic Science International 763D Concord Avenue Cambridge MA

Invivo Therapeutics Corp. One Kendall Square Cambridge MA

Page 36 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02139 Biotechnology Life Science

02140 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Academic/Nonprofit R&D Academic/Non-Profit

02138 Biotechnology Life Science

02142 Academic/Nonprofit R&D Academic/Non-Profit

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02140 Renewable Energy Clean Energy

02138 Biotechnology Life Science

02142 Medical Devices Life Science

Page 37 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Tissue engineering and regenerative medicine research and development 2016

Drug Development 2014

Orphan Drug Accelerator 2013

Academic Research Institution 1970

Digital biology consulting firm 2013

Nonprofit biotechnology company 1998

Immunotherapy platforms to treat cancer

R&D of novel therapeutics 1989

R&D of autoimmune and cancer drugs 2000

R&D in cell and gene therapeutics 2016

Solar Energy Development 2009

Developing clot-dissolving therapy 2006

R&D of Spinal Cord Injury Treatment Technology

Page 38 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.09491617478 42.3619392706752 (42.3619392706752, - 71.09491617478) -71.1489061819435 42.3954009280417 (42.3954009280417, - http://www.unumrx.com/ 71.1489061819435) -71.0927839228085 42.3638943145572 (42.3638943145572, - http://www.cydanco.com/ 71.0927839228085) -71.0864544597375 42.3614502811134 (42.3614502811134, - http://hst.mit.edu 71.0864544597375) -71.1334317705788 42.3808821913293 (42.3808821913293, - http://www.amberbiology.com/ 71.1334317705788) -71.0917711454075 42.3634083285031 (42.3634083285031, - http://www.als.net/ 71.0917711454075) -71.092829191189 42.3668780444442 (42.3668780444442, - http://www.oncorus.com/ 71.092829191189) -71.1046072695631 42.3586803275966 (42.3586803275966, - http://www.iderapharma.com/ 71.1046072695631) -71.0902284817783 42.3669537210037 (42.3669537210037, - http://www.merrimackpharma.com/ 71.0902284817783) -71.1122045152113 42.3695906454501 (42.3695906454501, - http://obsidiantx.com/ 71.1122045152113) -71.1211111567223 42.3864737262996 (42.3864737262996, - http://www.remenergyco.com 71.1211111567223) -71.1528283444272 42.3925467275244 (42.3925467275244, - http://www.tsillc.net 71.1528283444272) -71.0903221519948 42.3672909799538 (42.3672909799538, - http://www.invivotherapeutics.com 71.0903221519948)

Page 39 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

7 83 1 258 86

6 3 13 168 1098

7 87 1 258 217

5 84 3 283 425

12 25 12 210 959

7 87 1 258 217

7 70 1 258 168

11 117 4 151 347

3 73 7 258 68

13 66 5 110 166

8 98 2 210 811

1 8 10 289 1066

3 73 7 258 68

Page 40 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Apic Bio 35 Cambridgepark Drive Cambridge MA

Elstar Therapeutics 840 Memorial Drive Cambridge MA

Akrivis Technologies One Broadway Cambridge MA

Amide Technologies One Kendall Square Cambridge MA

Draper Laboratories 555 Technology Square Cambridge MA

Symbiota 100 Edwin H Land Blvd. Cambridge MA

Novartis 250 Massachusetts Ave Cambridge MA

Decimmune Therapeutics 55 Cambridge Parkway Cambridge MA

EQRx 50 Hampshire Street Cambridge MA

Generation Bio 301 Binney Street Cambridge MA

STG International Cambridge MA

Artax Biopharma One Broadway Cambridge MA

Avastus Preclinical Services 359 Allston Street Cambridge MA

Page 41 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02140 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02142 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02142 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02142 Biotechnology Life Science

Clean Technology Clean Energy

02142 Biopharmaceutical Life Science

02139 Biotechnology Life Science

Page 42 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Advancing therapies to treat rare diseases

R&D in cancer immunotherapies

Drug development

Peptide synthesis 2017

R&D in alterative fuels, engineering

R&D in plant microbiome 2000

R&D, Drug Development 1996

R&D in novel peptides& antibodies for acute, tissue damaging inflammation 2001

Drug development and delivery processes 2019

Drug development 2016

Non-profit, sustainable energy in developing countries 2005

Autoimmune and inflammatory disease therapy development 2013

Contract Research and Manufacturing 2013

Page 43 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.1435428235516 42.3948130745936 (42.3948130745936, - https://www.apic-bio.com/ 71.1435428235516) -71.1150750377726 42.3631052107115 (42.3631052107115, - http://elstartherapeutics.com/ 71.1150750377726) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.akrivis.com/ 71.0838266372968) -71.0902043074382 42.3666417762688 (42.3666417762688, - http://www.amidetech.com/ 71.0902043074382) -71.0903650365721 42.3645276940892 (42.3645276940892, - http://www.draper.com/ 71.0903650365721) -71.0777769159513 42.3640613396564 (42.3640613396564, - http://symbiota.org/docs/ 71.0777769159513) -71.0975758400457 42.3615928983788 (42.3615928983788, - http://www.novartis.com/ 71.0975758400457) -71.0762977105578 42.3657420050532 (42.3657420050532, - http://decimmune.com/ 71.0762977105578) -71.092829191189 42.3668780444442 (42.3668780444442, - http://www.eqrx.com/ 71.092829191189) -71.0879679450326 42.3665842178827 (42.3665842178827, - https://generationbio.com/ 71.0879679450326)

http://www.stginternational.org/ -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.artaxbiopharma.com/ 71.0838266372968) -71.1132303285694 42.3616289911378 (42.3616289911378, - https://www.avastusps.com/about- 71.1132303285694) us/contact-us/

Page 44 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

6 3 13 168 1007

13 82 5 241 322

4 79 8 277 295

3 73 7 258 68

7 87 1 258 398

4 65 8 218 153

11 117 4 145 130

4 65 8 218 153

7 70 1 258 168

4 71 8 117 310

4 79 8 277 295

11 20 4 143 106

Page 45 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Pegasystems 1 Rogers Street Cambridge MA

Outermost Therapeutics 700 Main Street Cambridge MA

Kanyos Bio One Kendall Square Cambridge MA

Wyzer Biosciences 85 Bolton Street Cambridge MA

Delta Search Labs 400 Technology Square Cambridge MA

Mitrobridge 1030 Massachusetts Ave Cambridge MA

Genevant 245 Main Street Cambridge MA

Pandion Therapeutics 700 Main Street Cambridge MA

AvroBio One Kendall Square Cambridge MA

EnBiotix 700 Main Street Cambridge MA

Definiens 125 CambridgePark Drive Cambridge MA

Syros Pharmaceuticals 620 Memorial Drive Cambridge MA

Lucy Therapeutics 501 Massachusetts Avenue Cambridge MA

Page 46 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Information Technology High Tech

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02140 Biopharmaceutical Life Science

02142 Biotechnology/IT Life Science

02139 Biopharmaceutical Life Science

02142 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02140 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biotechnology Life Science

Page 47 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Software Development 1983

Strategies to treat and prevent brain diseases 2018

Immunotechnology therapies for type-1 diabetes and celiac disease 2016

Focused on Sanger DNA sequencing services 2011

R&D 2001

R&D in small molecule therapeutics that improve mitochondrial functions

Drug development and delivery 2018

Developing bispecific antibody therapeutics 2016

Drug development

Developer of anti-infective, personal care, and industrial products 2012

Tissue phonemics company

Drug Development in gene control

Drug discovery 2017

Page 48 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0772451084797 42.3663573089197 (42.3663573089197, - http://www.pega.com 71.0772451084797) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.outermostrx.com/ 71.09491617478) -71.0903221519948 42.3672909799538 (42.3672909799538, - http://kanyos.com/ 71.0903221519948) -71.1305699529474 42.39003115429 (42.39003115429, - https://www.wyzerbio.com 71.1305699529474) -71.091951377916 42.3638464323303 (42.3638464323303, - http://www.deltasearchlabs.com 71.091951377916) -71.1122045152113 42.3695906454501 (42.3695906454501, - https://www.mitobridge.com/ 71.1122045152113) -71.0848274465445 42.362543834575 (42.362543834575, - https://genevant.com/ 71.0848274465445) -71.09491617478 42.3619392706752 (42.3619392706752, - http://www.pandiontx.com/ 71.09491617478) -71.0909213544418 42.3661335993384 (42.3661335993384, - http://www.avrobio.com/ 71.0909213544418) -71.09491617478 42.3619392706752 (42.3619392706752, - http://www.enbiotix.com/ 71.09491617478) -71.1457538393149 42.3950752907362 (42.3950752907362, - http://www.definiens.com/company 71.1457538393149) -71.1076001591032 42.3539087777099 (42.3539087777099, - http://www.syros.com/#about 71.1076001591032) -71.1014931241571 42.3642623755098 (42.3642623755098, - http://www.lucytherapeutics.com/ 71.1014931241571)

Page 49 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

4 65 8 226 163

7 83 1 258 86

3 73 7 258 68

8 97 2 16 727

7 87 1 258 217

13 66 5 110 166

5 88 3 280 145

7 83 1 258 86

3 73 7 258 68

7 83 1 258 86

6 3 13 168 1098

5 85 3 178 125

7 80 1 264 22

Page 50 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Gritstone Oncology 40 Erie Street Cambridge MA

Zapotec Energy 675 Massachusetts Avenue Cambridge MA

Janpix One Broadway Cambridge MA

Repare Therapeutics One Broadway Cambridge MA

Canon USA - Healthcare Optics Research Laboratory 210 Broadway Cambridge MA

Tidal Therapeutics 700 Main Street Cambridge MA

Harvard-MIT Biomedical Engineering Center 500 Technology Square Cambridge MA

Prometrika 100 CambridgePark Drive Cambridge MA

Axcella Health 840 Memorial Drive Cambridge MA

Monsanto 245 First Street Cambridge MA

Voyager Therapeutics 75 Sidney Street Cambridge MA

IQ Proteomics 840 Memorial Drive Cambridge MA

Vedere Bio 400 Technology Square Cambridge MA

Page 51 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02139 Biotechnology Life Science

02139 Clean Technology Clean Energy

02142 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02139 Information Technology High Tech

02139 Biotechnology Life Science

02142 Academic/Nonprofit R&D Academic/Non-Profit

02140 Contract Research Life Science

02139 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

Page 52 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Drug Development in cancer therapeutics

Solar Energy Development 1997

Oncology-focused startup

Drug development

Research laboratory focusing on biomedical technology 2013

2019

Academic Research Institution

Specializes in clinical trial research 2003

R&D for Orphan Diseases

Sustainable agriculture company 1901

R&D in life-changing gene therapies 2014

Quantitative multiplexed proteomic applications 2015

Gene therapy 2019

Page 53 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.1042275993795 42.3574194822637 (42.3574194822637, - http://www.gritstoneoncology.com/ 71.1042275993795) -71.1040820735933 42.3658127184955 (42.3658127184955, - http://www.zapotecenergy.com/ 71.1040820735933) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://www.janpixbio.com/ 71.0838266372968) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.reparerx.com/ 71.0838266372968) -71.0932182826967 42.3661132632655 (42.3661132632655, - http://www.usa.canon.com 71.0932182826967) -71.09491617478 42.3619392706752 (42.3619392706752, - 71.09491617478) -71.0924508948695 42.3634560218508 (42.3634560218508, - http://web.mit.edu/hst-program/erelab 71.0924508948695) -71.1446382682865 42.3944559207962 (42.3944559207962, - http://www.prometrika.com/ 71.1446382682865) -71.1150750377726 42.3631052107115 (42.3631052107115, - http://www.axcellahealth.com/ 71.1150750377726) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://www.monsanto.com/ 71.0787234936367) -71.1020735355447 42.3613172138348 (42.3613172138348, - http://www.voyagertherapeutics.com/ 71.1020735355447) -71.1150750377726 42.3631052107115 (42.3631052107115, - http://www.iqproteomics.com/ 71.1150750377726) -71.091951377916 42.3638464323303 (42.3638464323303, - http://www.vederebio.com/ 71.091951377916)

Page 54 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

11 114 4 147 481

10 75 6 264 378

4 79 8 277 295

4 79 8 277 295

7 77 1 130 63

7 83 1 258 86

7 87 1 258 217

6 3 13 168 1098

13 82 5 241 322

4 79 8 276 154

11 117 4 265 182

13 82 5 241 322

7 87 1 258 217

Page 55 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Era7 Bioinformatics One Broadway Cambridge MA

Elemental Machines 186 Alewife Brook Parkway Cambridge MA

Cancer Research Technology, Inc. 215 First Street Cambridge MA

Novopyxis One Broadway Cambridge MA

Anokion 1035 Cambridge Street Cambridge MA

Rodin Therapeutics 300 Technology Square Cambridge MA

Genometry 37 Spinelli Place Cambridge MA

Sesen Bio, Inc. 245 First Street Cambridge MA

Catamaran Bio 700 Main Street Cambridge MA

Facebook 100 Binney Street Cambridge MA

Aura Biosciences 85 Bolton Street Cambridge MA

Geek Offices 1035 Cambridge Street Cambridge MA

Pfizer 610 Main Street Cambridge MA

Page 56 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Biopharmaceutical Life Science

02138 Information Technology High Tech

02142 Nonprofit/R&D Life Science

02142 Biotechnology Life Science

02141 Biopharmaceutical Life Science

02142 Biopharmaceutical Life Science

02138 Contract Research Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Information Technology High Tech

02140 Biotechnology Life Science

02141 Incubator Coworking Space/Incubator 02139 Biopharmaceutical Life Science

Page 57 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Next Generation Sequencing service provider 2004

Specializes in Cancer Research 2002

Medical device, diagnostics development

Drug Development

R&D in neurological disorders 2013

Next generation gene expression profiling 2012

Drug delivery

Developer of allogeneic immune cell therapies 2020

Social Networking Site 2004

Nanosmart technology development 2007

Coworking Office Space

R&D in drug development 1980

Page 58 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0838266372968 42.3626255873632 (42.3626255873632, - http://era7bioinformatics.com/en/index.cf 71.0838266372968) m -71.1409496735256 42.3901598267712 (42.3901598267712, - http://elementalmachines.io/ 71.1409496735256) -71.0785437379441 42.3642063517586 (42.3642063517586, - http://www.cancertechnology.com 71.0785437379441) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.novopyxis.com/ 71.0838266372968) -71.0937041519439 42.3734936331323 (42.3734936331323, - http://www.amsbio.com/contactus.aspx 71.0937041519439) -71.0917711454075 42.3634083285031 (42.3634083285031, - http://rodintherapeutics.com/ 71.0917711454075) -71.1537133050666 42.3922967326194 (42.3922967326194, - http://www.genometry.com/ 71.1537133050666) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://www.sesenbio.com/ 71.0787234936367) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.catamaranbio.com/ 71.09491617478) -71.0805992117041 42.3652581293824 (42.3652581293824, - https://www.facebook.com/fbboston 71.0805992117041) -71.1305699529474 42.39003115429 (42.39003115429, - http://www.aurabiosciences.com 71.1305699529474) -71.0937041519439 42.3734936331323 (42.3734936331323, - http://geekoffices.com/ 71.0937041519439) -71.0940133114707 42.3628809096634 (42.3628809096634, - http://www.pfizer.com/ 71.0940133114707)

Page 59 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

4 79 8 277 295

1 11 10 169 965

4 79 8 276 318

4 79 8 277 295

3 48 7 191 900

7 87 1 258 217

1 8 10 289 1066

4 79 8 276 154

7 83 1 258 86

4 79 8 253 89

8 97 2 16 727

3 48 7 191 900

7 83 1 258 299

Page 60 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Bayer Life Hub 610 Main Street Cambridge MA

GVD Corp 45 Spinelli Place Cambridge MA

Disc Medecine 300 Technology Square Cambridge MA

Blue Bird Bio 60 Binney Street Cambridge MA

Kronos Bio 21 Erie Street Cambridge MA

Nano Terra 737 Concord Avenue Cambridge MA

Axxam One Broadway Cambridge MA

Etagen Pharma 245 First Street Cambridge MA

STIMIT 700 Main Street Cambridge MA

Oracle One Main Street Cambridge MA

Amathus Therapeutics, Inc. 700 Main Street Cambridge MA

Sage Therapeutics 215 First Street Cambridge MA

GNS Healthcare 196 Broadway Cambridge MA

Page 61 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02139 Biopharmaceutical Life Science

02138 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02138 Biotechnology Life Science

02142 Contract Research Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Information Technology High Tech

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

Page 62 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Innovation Center

Nanotechnology/polymer coatings

Developer of therapeutics to treat neurological diseases

Gene therapy for cancer research 1992

R&D cancer therapy 2017

Nano- and micro-technology development company 2005

Partner Research Organization

2014

Cancer immunotherapy

Cloud Computing 1977

Developer of small-molecule therapeutics 2018

R&D around the Nervous System 2011

Bioinformatics 2000

Page 63 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0940133114707 42.3628809096634 (42.3628809096634, - https://www.lifehubboston.bayer.com/ 71.0940133114707) -71.1535123967346 42.3924697070264 (42.3924697070264, - http://gvdcorp.com/ 71.1535123967346) -71.0917711454075 42.3634083285031 (42.3634083285031, - http://www.discmedicine.com/ 71.0917711454075) -71.0795170854724 42.3651201867491 (42.3651201867491, - http://www.bluebirdbio.com/ 71.0795170854724) -71.1038053210519 42.3578097131557 (42.3578097131557, - http://www.kronosbio.com/ 71.1038053210519) -71.1530606503875 42.3905262653211 (42.3905262653211, - http://www.nanoterra.com/ 71.1530606503875) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.axxam.com/ 71.0838266372968) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://www.etagenpharma.com/ 71.0787234936367) -71.09491617478 42.3619392706752 (42.3619392706752, - https://stimittx.com/ 71.09491617478) -71.0801548712499 42.3621050405824 (42.3621050405824, - http://www.oracle.com/index.html 71.0801548712499) -71.09491617478 42.3619392706752 (42.3619392706752, - 71.09491617478) -71.0785437379441 42.3642063517586 (42.3642063517586, - http://www.sagerx.com 71.0785437379441) -71.0924542632677 42.3658367858015 (42.3658367858015, - http://www.gnshealthcare.com 71.0924542632677)

Page 64 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

7 83 1 258 299

1 8 10 289 1066

7 87 1 258 217

4 79 8 253 35

11 117 4 147 124

1 8 10 286 1066

4 79 8 277 295

4 79 8 276 154

7 83 1 258 86

4 79 8 276 272

7 83 1 258 86

4 79 8 276 318

7 77 1 258 134

Page 65 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Vaxess Technologies 790 Memorial Drive Cambridge MA

ElevateBio 139 Main Street Cambridge MA

KSQ Therapeutics 610 Main Street Cambridge MA

Thrive Earlier Detection 38 Sidney Street Cambridge MA

Twitter 141 Portland Street Cambridge MA

EGenesis 300 Technology Square Cambridge MA

Sumitomo Dainippon Pharma Oncology 640 Memorial Drive Cambridge MA

Magenta Therapeutics 100 Technology Square Cambridge MA

Nanobiosym 245 First Street Cambridge MA

Fulcrum Therapeutics 26 Lansdowne Street Cambridge MA

Fire Hose Games 1035 Cambridge Street Cambridge MA

Travera 700 Main Street Cambridge MA

US Green Data 222 Third Street Cambridge MA

Page 66 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biotechnology High Tech

02139 Information Technology High Tech

02142 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Medical Devices Life Science

02139 Biopharmaceutical Life Science

02141 Information Technology High Tech

02139 Biotechnology Life Science

02141 Renewable Energy Clean Energy

Page 67 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Developing a pipeline of MIMIXâ„¢ therapies 2012

Cell and gene therapy

Drug Development

Cancer detection 2019

Social Media Developer 2006

Genome editing 2015

Cancer therapeutics company 2020

R&D in immune and blood-based diseases

Creating new technology for healthcare

Drug Development

Video Game Developer and Incubator 2011

Cancer Research 2017

Energy information analysis 2010

Page 68 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.1148317990337 42.3598764519961 (42.3598764519961, - http://www.vaxess.com 71.1148317990337) -71.0822616219526 42.3622223616064 (42.3622223616064, - https://elevate.bio/ 71.0822616219526) -71.0940133114707 42.3628809096634 (42.3628809096634, - http://ksqtx.com/ 71.0940133114707) -71.1009023296914 42.3615643305096 (42.3615643305096, - https://thrivedetect.com/ 71.1009023296914) -71.0922963004345 42.365576593007 (42.365576593007, - http://www.twitter.com 71.0922963004345) -71.0917711454075 42.3634083285031 (42.3634083285031, - http://www.egenesisbio.com/ 71.0917711454075) -71.1102284659553 42.3545195799064 (42.3545195799064, - https://www.sdponcology.com/ 71.1102284659553) -71.0907938787327 42.3629489687522 (42.3629489687522, - https://www.magentatx.com/contact/ 71.0907938787327) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://www.nanobiosym.com 71.0787234936367) -71.0990223853639 42.3610129940534 (42.3610129940534, - https://www.fulcrumtx.com/contact 71.0990223853639) -71.0937041519439 42.3734936331323 (42.3734936331323, - http://www.firehosegames.com/ 71.0937041519439) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.travera.com/ 71.09491617478) -71.0809909801686 42.3670782746947 (42.3670782746947, - http://www.usgreendata.com/ 71.0809909801686)

Page 69 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

11 20 4 243 42

4 79 8 276 295

7 83 1 258 299

11 117 4 265 487

7 77 1 258 134

7 87 1 258 217

11 114 4 178 101

7 87 1 258 398

4 79 8 276 154

11 117 4 265 239

3 48 7 191 900

7 83 1 258 86

4 71 8 117 33

Page 70 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Cambridge Innovation Center One Broadway Cambridge MA

Lipomed, Inc. 150 CambridgePark Drive Cambridge MA

Standard Molecular One Broadway Cambridge MA

Kernal Biologics 700 Main Street Cambridge MA

Q-State Biosciences 179 Sidney Street Cambridge MA

One Cell Systems, Inc. 100 Inman Street Cambridge MA

Intuit 150 CambridgePark Drive Cambridge MA

Immunitas Therapeutics 650 East Kendall Street Cambridge MA

Ally Therapeutics 325 Vassar Street Cambridge MA

Acceleron Pharma, Inc. 128 Sidney Street Cambridge MA

Glympse Bio 35 Cambridgepark Drive Cambridge MA

Angiogenesis Foundation One Broadway Cambridge MA

Expansion Technologies One Kendall Square Cambridge MA

Page 71 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Incubator Coworking Space/Incubator 02140 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02140 Information Technology High Tech

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02140 Biotechnology Life Science

02142 Academic/Nonprofit R&D Life Science

02142 Biotechnology Life Science

Page 72 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

600+ companies in one location 2001

R&D Health Care Company 1997

Personalized medicine, genetic testing, & tumor genomics 2014

mRNA vaccine and therapeutics company 2004

Human Diagnostic Development 2014

R&D in single cell assays 1992

Software developer

Drug discovery 2019

Gene therapy 2018

Biopharmaceutical R&D 2003

Development of synthetic biomarkers 2015

Research in angiogenesis-based medicine 1994

Bioimaging

Page 73 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.cictr.com/ 71.0838266372968) -71.1459500611312 42.3946110167458 (42.3946110167458, - http://www.lipomed.com 71.1459500611312) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.standardmolecular.com/ 71.0838266372968) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.kernalbio.com/ 71.09491617478) -71.1051011912218 42.3583424620476 (42.3583424620476, - http://www.qstatebio.com/ 71.1051011912218) -71.1015788078025 42.3718698253958 (42.3718698253958, - http://www.onecell.com/ 71.1015788078025) -71.1459500611312 42.3946110167458 (42.3946110167458, - http://www.intuit.com/ 71.1459500611312) -71.0810729236616 42.3645257329026 (42.3645257329026, - https://www.immunitastx.com 71.0810729236616) -71.1056951550591 42.3549339189278 (42.3549339189278, - https://www.allytx.com/ 71.1056951550591) -71.1034267910418 42.3594609731047 (42.3594609731047, - http://www.acceleronpharma.com 71.1034267910418) -71.1435428235516 42.3948130745936 (42.3948130745936, - http://glympsebio.com/ 71.1435428235516) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.angio.org/ 71.0838266372968) -71.0902043074382 42.3666417762688 (42.3666417762688, - http://www.extbio.com/ 71.0902043074382)

Page 74 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

4 79 8 277 295

6 3 13 168 1098

4 79 8 277 295

7 83 1 258 86

11 114 4 151 172

10 55 6 221 853

6 3 13 168 1098

4 79 8 276 154

5 85 3 160 125

11 117 4 147 226

6 3 13 168 1007

4 79 8 277 295

3 73 7 258 68

Page 75 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Carmine Therapeutics 700 Main Street Cambridge MA

Brammer Bio 250 Binney Street Cambridge MA

WuXi AppTec Sales 55 Cambridge Parkway Cambridge MA

Tiburio Therapeutics 700 Technology Square Cambridge MA

Verve Therapeutics 500 Technology Square Cambridge MA

Eutropics Pharmaceuticals 767-C Concord Ave Cambridge MA

Boston BioChem, Inc. 840 Memorial Drive Cambridge MA

Mersana Therapeutics 840 Memorial Drive Cambridge MA

Constellation Pharmaceuticals 215 First Street Cambridge MA

Neurocycle Therapeutics One Broadway Cambridge MA

Nuritas One Broadway Cambridge MA

Energesis Pharmaceuticals One Kendall Square Cambridge MA

MIT Energy Initiative 77 Massachusetts Ave E19-307 Cambridge MA

Page 76 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Information Technology/Healthcare Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02138 Biopharmaceutical Life Science

02139 Contract Research Life Science

02139 Biopharmaceutical Life Science

02142 Biopharmaceutical Life Science

02142 Biopharmaceutical Life Science

02142 Biotechnology High Tech

02142 Biopharmaceutical Life Science

02142 Academic/Research Academic/Non-Profit

Page 77 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Developing genetic medicines based on red blood cell extracellular vesicles 2019

CDMO cell therapy

Tech App platform for the drug R&D process 2000

Develops and manufactures endocrine system medicines

Drug discovery and development 2018

R&D in cancer 2005

Produces ubiquitin proteasome pathway products 1997

Cancer compounds 2002

Development in Epigenetics 2008

Drug discovery and development 2017

Combines artificial intelligence and genomics 2014

Drug development

Research in energy technology 2006

Page 78 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.09491617478 42.3619392706752 (42.3619392706752, - https://www.carminetherapeutics.com/ 71.09491617478) -71.0868051833275 42.3657359802891 (42.3657359802891, - https://www.brammerbio.com/ 71.0868051833275) -71.0762977105578 42.3657420050532 (42.3657420050532, - http://www.wuxiapptec.com/ 71.0762977105578) -71.0927839228085 42.3638943145572 (42.3638943145572, - http://www.tiburio.com/ 71.0927839228085) -71.0924508948695 42.3634560218508 (42.3634560218508, - http://www.vervetx.com/ 71.0924508948695) -71.1532072993002 42.3927723484994 (42.3927723484994, - http://www.eutropics.com 71.1532072993002) -71.1150750377726 42.3631052107115 (42.3631052107115, - http://www.bostonbiochem.com 71.1150750377726) -71.1150750377726 42.3631052107115 (42.3631052107115, - http://www.mersana.com/ 71.1150750377726) -71.0785437379441 42.3642063517586 (42.3642063517586, - http://www.constellationpharma.com/ 71.0785437379441) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://neurocycletherapeutics.com/ 71.0838266372968) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.nuritas.com/ 71.0838266372968) -71.0911051057089 42.3663645885345 (42.3663645885345, - http://energesispharma.com/ 71.0911051057089) -71.0878251224377 42.3624197298936 (42.3624197298936, - http://mitei.mit.edu 71.0878251224377)

Page 79 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

7 83 1 258 86

4 79 8 279 270

4 65 8 218 153

7 87 1 258 217

7 87 1 258 217

1 8 10 289 1066

13 82 5 241 322

13 82 5 241 322

4 79 8 276 318

4 79 8 277 295

4 79 8 277 295

3 73 7 258 68

5 84 3 272 425

Page 80 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

US Offshore Wind Collaborative One Broadway Cambridge MA

EIP Pharma 210 Broadway Cambridge MA

Picower Institute for Learning and Memory 43 Vassar St Cambridge MA

Genocea Biosciences 100 Acorn Park Drive Cambridge MA

Akashi Therapeutics 245 First Street Cambridge MA

Codiak Biosciences 500 Technology Square Cambridge MA

DSM Innovation Center One Broadway Cambridge MA

Aurora Flight Sciences 90 Broadway Cambridge MA

Samyang Biopharm USA One Kendall Square Cambridge MA

Mediar Therapeutics 700 Main Street Cambridge MA

Biogen Idec Innovation Incubator 225 Binney Street Cambridge MA

Science Hotel 790 Memorial Drive Cambridge MA

Lysogene 245 First Street Cambridge MA

Page 81 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Renewable Energy Life Science

02139 Biopharmaceutical Life Science

02142 Academic/Nonprofit R&D Academic/Non-Profit

02140 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Incubator Coworking Space/Incubator 02142 Biotechnology Life Science

Page 82 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Non-Profit organization working on the offshore wind energy market 2005

Developing neflamapimod 2014

Academic Research Institution 1994

Vaccine R&D 2006

R&D of therapies for DMD and pediatric diseases 2010

Exosome Biology

R&D on therapeutic cells 1902

R&D in aerospace vehicles 1989

Biologics development in oncology and rare disease 2018

Developer of medicines to address fibrosis 2019

R&D Incubator

R&D Lab Incubator

R&D in neurodegenerative diseases 2009

Page 83 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0838266372968 42.3626255873632 (42.3626255873632, - http://usoffshorewind.org/ 71.0838266372968) -71.0932182826967 42.3661132632655 (42.3661132632655, - http://www.eippharma.com/ 71.0932182826967) -71.091428219345 42.362113822768 (42.362113822768, - http://picower.mit.edu 71.091428219345) -71.1496528305172 42.3981084327217 (42.3981084327217, - https://www.genocea.com/ 71.1496528305172) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://akashirx.com/ 71.0787234936367) -71.0924508948695 42.3634560218508 (42.3634560218508, - http://www.codiakbio.com/ 71.0924508948695) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.dsm.com 71.0838266372968) -71.0871433250208 42.3636524285693 (42.3636524285693, - http://www.aurora.aero/ 71.0871433250208) -71.0911051057089 42.3663645885345 (42.3663645885345, - http://us.samyangbiopharm.com/ 71.0911051057089) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.mediartx.com/ 71.09491617478) -71.08567301266 42.3662549989373 (42.3662549989373, - https://www.biogen.com/en_us/contact.h 71.08567301266) tml -71.1148317990337 42.3598764519961 (42.3598764519961, - http://www.are.com/greater-boston.html 71.1148317990337) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://www.lysogene.com/ 71.0787234936367)

Page 84 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

4 79 8 277 295

7 77 1 130 63

5 90 3 270 478

6 3 13 3 1010

4 79 8 276 154

7 87 1 258 217

4 79 8 277 295

5 88 3 280 145

3 73 7 258 68

7 83 1 258 86

4 71 8 252 424

11 20 4 243 42

4 79 8 276 154

Page 85 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

WAVE Life Sciences 733 Concord Ave Cambridge MA

Ethismos Research Inc One Broadway Cambridge MA

Tiba Biotech One Broadway Cambridge MA

Eli Lilly 450 Kendall Street Cambridge MA

MedPanel 50 Church Street Cambridge MA

VL50 One Kendall Square Cambridge MA

Next Jump One Kendall Square Cambridge MA

MIT Clinical Research Center 45 Carleton Street Cambridge MA

HubSpot 25 First Street Cambridge MA

Rubius Therapeutics 399 Binney Street Cambridge MA

Hybrigenics Services One Broadway Cambridge MA

Genosco 767-C Concord Ave Cambridge MA

Vor Biopharma 100 CambridgePark Drive Cambridge MA

Page 86 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02138 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02138 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02142 Information Technology High Tech

02142 Academic/Nonprofit R&D Academic/Non-Profit

02141 Information Technology High Tech

02142 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02138 Biotechnology Life Science

02140 Biopharmaceutical Life Science

Page 87 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

R&D in Nucleic acid therapeutics

R&D in novel medicines for major depressive disorder and ADHD

Developing vaccines and immunotherapies 2017

Drug delivery and device innovation center 2015

Full service healthcare market research firm

Post-transcriptional modifications platform

E-Commerce Solutions 1994

Lab-Research and Development 1964

Internet Marketing Software 2006

Enucleated cells therapeutics

Research Products and Instrumentation

R&D in Human Diseases

Immuno-oncology company

Page 88 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.1531364827633 42.3911021505754 (42.3911021505754, - http://www.wavelifesciences.com/ 71.1531364827633) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://www.ethismos.com/ 71.0838266372968) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.tiba.bio/ 71.0838266372968) -71.0817284552779 42.3634864743587 (42.3634864743587, - http://www.lilly.com/Pages/Home.aspx 71.0817284552779) -71.120551880288 42.3742459391683 (42.3742459391683, - https://www.medpanel.com/ 71.120551880288) -71.0896391378324 42.3673859562795 (42.3673859562795, - 71.0896391378324) -71.0903221519948 42.3672909799538 (42.3672909799538, - http://www.nextjump.com 71.0903221519948) -71.0864544597375 42.3614502811134 (42.3614502811134, - http://crc.mit.edu 71.0864544597375) -71.0772857119759 42.3696017222785 (42.3696017222785, - http://www.hubspot.com/ 71.0772857119759) -71.0902337857325 42.3676019682682 (42.3676019682682, - http://www.rubiustx.com/ 71.0902337857325) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://www.hybrigenics-services.com/ 71.0838266372968) -71.1532072993002 42.3927723484994 (42.3927723484994, - http://www.genosco.com 71.1532072993002) -71.1446382682865 42.3944559207962 (42.3944559207962, - http://www.vorbiopharma.com 71.1446382682865)

Page 89 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

1 8 10 286 1066

4 79 8 277 295

4 79 8 277 295

4 79 8 276 154

12 103 12 197 818

3 61 7 117 723

3 73 7 258 68

5 84 3 283 425

4 57 8 226 151

3 61 7 117 723

4 79 8 277 295

1 8 10 289 1066

6 3 13 168 1098

Page 90 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Tiaki Therapeutics 700 Main Street Cambridge MA

Burke Bioventures One Broadway Cambridge MA

Custom Made 90 Sherman Street Cambridge MA

PanTher Therapeutics 700 Main Street Cambridge MA

Intersystems Corporation One Memorial Drive Cambridge MA

MicroContinuim 57 Smith Place Cambridge MA

Omega Therapeutics 20 Acorn Park Drive Cambridge MA

Disarm Therapeutics One Main Street Cambridge MA

WeWork 625 Massachusetts Ave Cambridge MA

Synlogic Inc. 301 Binney Street Cambridge MA

Akebia Therapeutics 245 First Street Cambridge MA

Zimmer Etex 675 Massachusetts Avenue Cambridge MA

Potenza Therapeutics 1030 Massachusetts Ave Cambridge MA

Page 91 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02140 Information Technology High Tech

02139 Biotechnology Life Science

02142 Information Technology High Tech

02138 Biotechnology Life Science

02140 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Coworking Space Coworking Space/Incubator 02142 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02139 Biotechnology Life Science

Page 92 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Developing therapeutics for dementias 2017

Drug development

Online custom designed platform 2009

Chemotherapeutic response improvement 2014

Software Application Development 1978

Development in solar & electronics technology 1998

Preclinical stage genomic medicine 2017

Developer of therapeutics to prevent axonal degeneration 2016

Flexible office coworking space

Synthetic biotics platform development

R&D on Hypoxia inducible factor biology 2007

R&D in bone repair and regeneration 1989

R&D in oncology/immunotherapy 2014

Page 93 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.09491617478 42.3619392706752 (42.3619392706752, - http://www.tiakitx.com/ 71.09491617478) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.burkebioventures.com 71.0838266372968) -71.1323849678653 42.3884908047309 (42.3884908047309, - http://www.custommade.com 71.1323849678653) -71.09491617478 42.3619392706752 (42.3619392706752, - http://www.panthertx.com/ 71.09491617478) -71.0812562847235 42.3613569943424 (42.3613569943424, - http://www.intersystems.com 71.0812562847235) -71.1519193028896 42.3926977768483 (42.3926977768483, - http://www.microcontinuum.com/ 71.1519193028896) -71.147298571881 42.3981061523318 (42.3981061523318, - http://www.omegatherapeutics.com/ 71.147298571881) -71.0801548712499 42.3621050405824 (42.3621050405824, - https://www.disarmtx.com/ 71.0801548712499) -71.1034839676115 42.3654554769794 (42.3654554769794, - http://www.wework.com 71.1034839676115) -71.0879679450326 42.3665842178827 (42.3665842178827, - http://www.synlogictx.com/ 71.0879679450326) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://akebia.com/ 71.0787234936367) -71.1040820735933 42.3658127184955 (42.3658127184955, - https://etexcorp.com/ 71.1040820735933) -71.1122045152113 42.3695906454501 (42.3695906454501, - http://potenzatherapeutics.com/ 71.1122045152113)

Page 94 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

7 83 1 258 86

4 79 8 277 295

8 97 2 20 868

7 83 1 258 86

5 84 3 180 149

1 8 10 289 1066

6 3 13 3 1010

4 79 8 276 272

7 80 1 264 405

4 71 8 117 310

4 79 8 276 154

10 75 6 264 378

13 66 5 110 166

Page 95 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Actipulse Neuroscience 210 Broadway Cambridge MA

Eleven Biotherapeutics 245 First Street Cambridge MA

Invaio Sciences 75 Moulton Street Cambridge MA

Stemcell Technologies 222 Third Street Cambridge MA

CAMP4 Therapeutics One Kendall Square Cambridge MA

Abcam, Inc. One Kendall Square Cambridge MA

Ragon Institute of MGH, MIT and Harvard 400 Technology Square Cambridge MA

BioAnalytix 790 Memorial Drive Cambridge MA

Eight Spokes 101 Main Street Cambridge MA

MicroQuin 700 Main Street Cambridge MA

SciFluor Life Sciences 300 Technology Square Cambridge MA

Cocoon Biotech 700 Main Street Cambridge MA

Luca Biologics Cambridge MA

Page 96 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02138 Biotechnology Life Science

02141 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Academic/Nonprofit R&D Academic/Non-Profit

02139 Biopharmaceutical Life Science

02142 Biotechnology High Tech

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02139 Biotechnology Life Science

Biotechnology Life Science

Page 97 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Medical company specialized in non invasive brain stimulation technologies 2017

Drug Development 2010

2018

Research Products and Instrumentation

Drug discovery and development 2016

Produces & catalogs antibodies 1992

AIDS/HIV and immunology research institution 2009

R&D in biologic and biosimilar drugs

Cloud Software for Project Development

Cancer therapeutics company

R&D in fluorine chemistry/PET traces 2011

Arthritis treatment 2013

Drug development 2019

Page 98 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0932182826967 42.3661132632655 (42.3661132632655, - https://actipulse.com/ 71.0932182826967) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://www.elevenbio.com 71.0787234936367) -71.1480683928401 42.3922152102531 (42.3922152102531, - https://www.invaio.com/ 71.1480683928401) -71.0809909801686 42.3670782746947 (42.3670782746947, - https://www.stemcell.com/ 71.0809909801686) -71.0903221519948 42.3672909799538 (42.3672909799538, - https://www.camp4tx.com/ 71.0903221519948) -71.0909213544418 42.3661335993384 (42.3661335993384, - http://www.abcam.com 71.0909213544418) -71.091951377916 42.3638464323303 (42.3638464323303, - http://www.ragoninstitute.org/ 71.091951377916) -71.1148317990337 42.3598764519961 (42.3598764519961, - http://www.bioanalytixinc.com/index.html 71.1148317990337) -71.0815834855672 42.3622099312421 (42.3622099312421, - https://www.eightspokes.com/ 71.0815834855672) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.microquin.com/ 71.09491617478) -71.0917711454075 42.3634083285031 (42.3634083285031, - http://www.scifluor.com/ 71.0917711454075) -71.09491617478 42.3619392706752 (42.3619392706752, - http://www.cocoonbiotech.com 71.09491617478)

https://luca.bio/

Page 99 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

7 77 1 130 63

4 79 8 276 154

1 9 10 244 1044

4 71 8 117 33

3 73 7 258 68

3 73 7 258 68

7 87 1 258 217

11 20 4 243 42

4 79 8 276 272

7 83 1 258 86

7 87 1 258 217

7 83 1 258 86

Page 100 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Cellarity 100 Technology Square Cambridge MA

AVEO Pharmaceuticals One Broadway Cambridge MA

Pyxis Oncology 35 Cambridgepark Drive Cambridge MA

Cadent Therapeutics 60 Hamilton Street Cambridge MA

Row Analytics One Broadway Cambridge MA

Ultragenyx 840 Memorial Drive Cambridge MA

Novellus 1035 Cambridge Street Cambridge MA

XGenomes Corp. 501 Massachusetts Avenue Cambridge MA

Epizyme, Inc. 400 Technology Square Cambridge MA

Beam Therapeutics 26 Landsdowne Street Cambridge MA

Servier 700 Main Street Cambridge MA

Koa Labs 66 Church St Cambridge MA

Exo Therapeutics 700 Main Street Cambridge MA

Page 101 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02140 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02141 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02138 Incubator Life Science

02139 Biotechnology Life Science

Page 102 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Digitizing molecular information in cells 2017

R&D in novel, targeted cancer therapeutic drugs 2002

Developing antibody therapeutics for cancer treatment 2019

Precision neuroscience company 2017

AI and disease research

R&D in gene therapy 2013

Developer of engineered cellular medicines 2015

Developer of DNA sequencing technologies

Drug Development 2007

Developer of precision genetic medicines using CRISPR base editing 2018

Biopharmaceutical R&D

Incubator Space 2012

Drug development 2018

Page 103 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0907938787327 42.3629489687522 (42.3629489687522, - https://cellarity.com/ 71.0907938787327) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.aveopharma.com 71.0838266372968) -71.1435428235516 42.3948130745936 (42.3948130745936, - https://www.pyxisoncology.com/ 71.1435428235516) -71.1056266569763 42.3579020246661 (42.3579020246661, - http://www.cadenttx.com 71.1056266569763) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://rowanalytics.com/ 71.0838266372968) -71.1150750377726 42.3631052107115 (42.3631052107115, - http://www.ultragenyx.com/ 71.1150750377726) -71.0937041519439 42.3734936331323 (42.3734936331323, - http://novellus-inc.com/ 71.0937041519439) -71.1014931241571 42.3642623755098 (42.3642623755098, - http://www.xgenomes.com/ 71.1014931241571) -71.091951377916 42.3638464323303 (42.3638464323303, - http://www.epizyme.com 71.091951377916) -71.0990223853639 42.3610129940534 (42.3610129940534, - https://beamtx.com/contact/ 71.0990223853639) -71.09491617478 42.3619392706752 (42.3619392706752, - https://servier.com/en/ 71.09491617478) -71.1212071580752 42.3739809997343 (42.3739809997343, - http://www.koalab.com 71.1212071580752) -71.09491617478 42.3619392706752 (42.3619392706752, - https://labcentral.org/resident- 71.09491617478) companies/exo

Page 104 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

7 87 1 258 398

4 79 8 277 295

6 3 13 168 1007

11 114 4 151 484

4 79 8 277 295

13 82 5 241 322

3 48 7 191 900

7 80 1 264 22

7 87 1 258 217

11 117 4 265 239

7 83 1 258 86

12 103 12 197 818

7 83 1 258 86

Page 105 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

SIRION Biotech International 125 Cambridge Park Drive Cambridge MA

Aquinnah Pharmaceuticals 610 Main Street Cambridge MA

Portal Instruments 190 Fifth Street Cambridge MA

Sanofi-Aventis Pharmaceuticals 270 Albany Street Cambridge MA

AMSBIO LLC 1035 Cambridge Street Cambridge MA

Foghorn Therapeutics 100 Binney Street Cambridge MA

Ohana Biosciences 325 Vassar Street Cambridge MA

Reveal Pharmaceuticals 37 Prentiss Street Cambridge MA

Cue Therapeutics 21 Erie Street Cambridge MA

Bill & Melinda Gates Medical Research Institute 245 Main St Cambridge MA

Black Diamond Therapeutics 139 Main Street Cambridge MA

Revitope Oncology 610 Main Street Cambridge MA

Foundation Medicine 150 Second Street Cambridge MA

Page 106 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02140 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02141 Medical Devices Life Science

02139 Biopharmaceutical Life Science

02141 Contract Research Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02140 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02141 Biotechnology Life Science

Page 107 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Gene and cell therapy, vaccine development 2005

Neurodegenerative drug development 2014

Medical Devices

R&D in drug development 2000

Research reagents 1987

R&D in Gene Control 2016

Reproductive health 2016

Gadolinium free MRI contrast agent 2016

R&D in immunotherapy

Non-profit biotech organization focused on translational medicine 2017

Precision oncology medicine company 2017

Cancer immunotherapy 2016

R&D in cancer medicine 2010

Page 108 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.1457538393149 42.3950752907362 (42.3950752907362, - https://www.sirion-biotech.com/ 71.1457538393149) -71.0940133114707 42.3628809096634 (42.3628809096634, - https://www.aquinnahpharma.com/ 71.0940133114707) -71.0836331755733 42.3675617268696 (42.3675617268696, - https://www.portalinstruments.com/ 71.0836331755733) -71.1021283268448 42.3575705643314 (42.3575705643314, - http://en.sanofi.com/ 71.1021283268448) -71.0937041519439 42.3734936331323 (42.3734936331323, - http://www.amsbio.com/ 71.0937041519439) -71.0805992117041 42.3652581293824 (42.3652581293824, - http://foghorntx.com/ 71.0805992117041) -71.1056951550591 42.3549339189278 (42.3549339189278, - https://www.ohanabio.com/ 71.1056951550591) -71.1169713306477 42.384511873517 (42.384511873517, - http://www.revealpharma.com/ 71.1169713306477) -71.1038053210519 42.3578097131557 (42.3578097131557, - https://www.cuebiopharma.com/ 71.1038053210519) -71.0848274465445 42.362543834575 (42.362543834575, - https://www.gatesmri.org/ 71.0848274465445) -71.0822616219526 42.3622223616064 (42.3622223616064, - https://www.blackdiamondtherapeutics.c 71.0822616219526) om -71.0940133114707 42.3628809096634 (42.3628809096634, - http://www.revitope.com/ 71.0940133114707) -71.0790906560675 42.3669436404215 (42.3669436404215, - http://www.foundationmedicine.com 71.0790906560675)

Page 109 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

6 3 13 168 1098

7 83 1 258 299

4 60 8 117 262

11 117 4 147 233

3 48 7 191 900

4 79 8 253 89

5 85 3 160 125

9 100 9 208 643

11 117 4 147 124

5 88 3 280 145

4 79 8 276 295

7 83 1 258 299

4 71 8 112 268

Page 110 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Scilligence 701 Concord Ave Cambridge MA

MIT Brain and Cognitive Sciences Center 77 Massachusetts Ave Cambridge MA

Caraway Therapeutics 300 Technology Square Cambridge MA

Vivtex 700 Main Street Cambridge MA

Boston Pharmaceuticals 55 Cambridge Parkway Cambridge MA

Genfit Corp. 185 Alewife Brook Pkwy Cambridge MA

Cellino Biotech 501 Massachusetts Ave Cambridge MA

H3 Biomedicine 300 Technology Square Cambridge MA

Apeiron Synthesis One Broadway Cambridge MA

RedStar Ventures One Kendall Square Cambridge MA

Proclara Biosciences 85 Bolton Street Cambridge MA

Protnutria Biosciences 840 Memorial Drive Cambridge MA

PhAST Diagnostics 325 Vassar Street Cambridge MA

Page 111 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02138 Biotechnology Life Science

02142 Academic/Nonprofit R&D Academic/Non-Profit

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02138 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Entrepreneurship High Tech

02140 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02139 Biotechnology Life Science

Page 112 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

R&D Informatics Insights

Academic Research Institution

Biotherapeutic company

Drug development 2018

Drug Development 2015

R&D in medication for cardio metabolic disease 1999

Develops intracellular delivery lasers and nanotechnology

R&D in Cancer Research 2001

Contract Research and Manufacturing 2010

Company that helps grow companies 2010

R&D in protein misfolding diseases 2016

R&D in amino acids pharmacology 2010

Develops rapid diagnostic technology 2017

Page 113 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.1513289552288 42.3903054076996 (42.3903054076996, - http://www.scilligence.com/web/ 71.1513289552288) -71.091428219345 42.362113822768 (42.362113822768, - http://bcs.mit.edu/ 71.091428219345) -71.0917711454075 42.3634083285031 (42.3634083285031, - https://carawaytx.com/ 71.0917711454075) -71.09491617478 42.3619392706752 (42.3619392706752, - http://www.vivtex.com/ 71.09491617478) -71.0762977105578 42.3657420050532 (42.3657420050532, - http://www.bostonpharmaceuticals.com/ 71.0762977105578) -71.142276992259 42.3904955493343 (42.3904955493343, - http://www.genfit.com/ 71.142276992259) -71.1014931241571 42.3642623755098 (42.3642623755098, - https://www.cellinobio.com 71.1014931241571) -71.0917711454075 42.3634083285031 (42.3634083285031, - http://www.h3biomedicine.com/ 71.0917711454075) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.apeiron-synthesis.com 71.0838266372968) -71.0902043074382 42.3666417762688 (42.3666417762688, - http://redstar.com/ 71.0902043074382) -71.1305699529474 42.39003115429 (42.39003115429, - http://www.proclarabio.com/ 71.1305699529474) -71.1150750377726 42.3631052107115 (42.3631052107115, - http://www.pronutria.com/ 71.1150750377726) -71.1056951550591 42.3549339189278 (42.3549339189278, - https://phastdiagnostics.com/ 71.1056951550591)

Page 114 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

1 8 10 286 1066

5 90 3 270 478

7 87 1 258 217

7 83 1 258 86

4 65 8 218 153

1 9 10 246 1022

7 80 1 264 22

7 87 1 258 217

4 79 8 277 295

3 73 7 258 68

8 97 2 16 727

13 82 5 241 322

5 85 3 160 125

Page 115 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Checkmate Pharmaceuticals 101 Main Street Cambridge MA

Goldfinch Bio 215 First Street Cambridge MA

Piper Therapeutics One Broadway Cambridge MA

Center for Human Genetics 840 Memorial Drive Cambridge MA

Nanobiotix 210 Broadway Cambridge MA

Mantle Biotech 700 Main Street Cambridge MA

Rheos Medicines 38 Sidney Street Cambridge MA

Generate Biomedicines 26 Landsdowne Street Cambridge MA

AnTolRx One Kendall Square Cambridge MA

Civetta Therapeutics 650 East Kendall Street Cambridge MA

edX 141 Portland Street Cambridge MA

Acworth Pharmaceuticals 700 Main Street Cambridge MA

NEO Scientific 245 First Street Cambridge MA

Page 116 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Non-Profit Life Science

02139 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Non-Profit Academic/Non-Profit

02139 Biotechnology Life Science

02142 Contract Research Life Science

Page 117 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Drug Development 2016

Drug Development in kidney diseases

R&D in autoimmune diseases 2015

Genetic testing and counseling services

R&D in nanomedicine for local treatment of cancer 2003

Medical diagnostics

Drug development 2018

Drug development

Development of novel patented therapies for autoimmune diseases

Cancer therapeutics company 2019

Education Program 2012

Preclinical development of novel treatments for cancers 2018

Provider of high quality research reagents

Page 118 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0815834855672 42.3622099312421 (42.3622099312421, - http://checkmatepharma.com/ 71.0815834855672) -71.0785437379441 42.3642063517586 (42.3642063517586, - https://www.goldfinchbio.com/ 71.0785437379441) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.pipertx.com/index.html 71.0838266372968) -71.1150750377726 42.3631052107115 (42.3631052107115, - http://chginc.org/ 71.1150750377726) -71.0932182826967 42.3661132632655 (42.3661132632655, - http://www.nanobiotix.com/ 71.0932182826967) -71.09491617478 42.3619392706752 (42.3619392706752, - http://mantlebiotech.com 71.09491617478) -71.1009023296914 42.3615643305096 (42.3615643305096, - http://www.rheosrx.com/ 71.1009023296914) -71.0990223853639 42.3610129940534 (42.3610129940534, - https://generatebiomedicines.com/ 71.0990223853639) -71.0903221519948 42.3672909799538 (42.3672909799538, - https://antolrx.com/ 71.0903221519948) -71.0810729236616 42.3645257329026 (42.3645257329026, - https://www.civettatherapeutics.com/ 71.0810729236616) -71.0922963004345 42.365576593007 (42.365576593007, - https://www.edx.org 71.0922963004345) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.acworthpharma.com/ 71.09491617478) -71.0787234936367 42.3635391601232 (42.3635391601232, - https://neobiolab.com/contact-us 71.0787234936367)

Page 119 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

4 79 8 276 272

4 79 8 276 318

4 79 8 277 295

13 82 5 241 322

7 77 1 130 63

7 83 1 258 86

11 117 4 265 487

11 117 4 265 239

3 73 7 258 68

4 79 8 276 154

7 77 1 258 134

7 83 1 258 86

4 79 8 276 154

Page 120 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Orum Therapeutics 20 Acorn Park Drive Cambridge MA

Cullinan Oncology One Main Street Cambridge MA

Fog Pharma 100 Acorn Park Drive Cambridge MA

Cogo Labs One Kendall Square Cambridge MA

EnClear Therapies One Broadway Cambridge MA

Hydra Biosciences 45 Moulton Street Cambridge MA

Strand Therapeutics One Kendall Square Cambridge MA

NovoBiotic Pharmaceuticals 767C Concord Avenue Cambridge MA

Factor Bioscience 1035 Cambridge Street Cambridge MA

Dyno Therapeutics 610 Main Street Cambridge MA

Boston Open Labs 763-D Concord Ave Cambridge MA

Takeda Oncology 40 Lansdowne Street Cambridge MA

Ring Therapeutics 55 Cambridge Parkway Cambridge MA

Page 121 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02140 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02140 Biopharmaceutical Life Science

02142 Information Technology High Tech

02142 Biopharmaceutical Life Science

02138 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02138 Biopharmaceutical Life Science

02141 Biotechnology Life Science

02139 Biotechnology Life Science

02138 Contract Research Life Science

02139 Biopharmaceutical Life Science

02142 Biotechnology Life Science

Page 122 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Creating cell penetrating therapeutic antibodies 2016

Drug development

R&D in miniproteins 2016

Web Incubator 2005

Developing therapies for neurodegenerative disease 2018

Drug development using novel ion channels 2001

mRNA therapeutics 2017

Development of novel antibiotics 2003

Regenerative medecine

AI-powered gene therapies 2018

Contract Research in open lab format 2009

R&D in drug development 1993

Discovering and developing Anellovector therapeutics 2017

Page 123 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.147298571881 42.3981061523318 (42.3981061523318, - https://www.orumrx.com/ 71.147298571881) -71.0801548712499 42.3621050405824 (42.3621050405824, - https://www.cullinanoncology.com/ 71.0801548712499) -71.1496528305172 42.3981084327217 (42.3981084327217, - http://www.fogpharma.com/ 71.1496528305172) -71.0901835021388 42.3666888663926 (42.3666888663926, - http://www.cogolabs.com 71.0901835021388) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.encleartherapies.com/ 71.0838266372968) -71.1479922742536 42.3909764936268 (42.3909764936268, - http://www.hydrabiosciences.com/ 71.1479922742536) -71.0911051057089 42.3663645885345 (42.3663645885345, - https://www.strandtx.com/ 71.0911051057089) -71.1532072993002 42.3927723484994 (42.3927723484994, - http://www.novobiotic.com/ 71.1532072993002) -71.0937041519439 42.3734936331323 (42.3734936331323, - https://factor.bio/ 71.0937041519439) -71.0940133114707 42.3628809096634 (42.3628809096634, - http://www.dynotx.com/ 71.0940133114707) -71.1528283444272 42.3925467275244 (42.3925467275244, - http://www.bolresearch.com/ 71.1528283444272) -71.0998226166888 42.3605729835869 (42.3605729835869, - https://www.takedaoncology.com/ 71.0998226166888) -71.0762977105578 42.3657420050532 (42.3657420050532, - http://www.ringtx.com/ 71.0762977105578)

Page 124 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

6 3 13 3 1010

4 79 8 276 272

6 3 13 3 1010

3 73 7 258 68

4 79 8 277 295

1 9 10 244 740

3 73 7 258 68

1 8 10 289 1066

3 48 7 191 900

7 83 1 258 299

1 8 10 289 1066

11 117 4 265 239

4 65 8 218 153

Page 125 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

GoDaddy One Main Street Cambridge MA

Sigilon 100 Binney Street Cambridge MA

Immuneering Corporation 245 Main St Cambridge MA

Good Start Genetics 237 Putnam Ave Cambridge MA

Alxerion Biotech Corporation 245 First Street Cambridge MA

Rent24 Coworking 618 Cambridge Street Cambridge MA

Agios Pharmaceuticals 86 Sidney Street Cambridge MA

Daedalus Software, Inc. One Broadway Cambridge MA

Hopewell Therapeutics 700 Main Street Cambridge MA

Hewlett-Packard Vertica Systems 150 CambridgePark Drive Cambridge MA

Boston Biomedical, Inc. 640 Memorial Drive Cambridge MA

Braizon Therapeutics 700 Main Street Cambridge MA

MYOMO One Broadway Cambridge MA

Page 126 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Information Technology High Tech

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02141 Coworking Space Coworking Space/Incubator 02139 Biopharmaceutical Life Science

02142 Information Technology High Tech

02139 Biotechnology Life Science

02140 Information Technology High Tech

02139 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

Page 127 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Web hosting and domain services 1997

Creating biomedical technologies

Human Diagnostic Development 2008

Human Diagnostic - Carrier Screening 2010

Exosome therapeutics 2017

Coworking Office Space 2016

Cancer Research 2008

Software Development 2000

Drug delivery

Data storage and analytics

R&D in Cancer Stem Cells 2013

Developer of central nervous system drug delivery system

Develops myoelectric prosthetic technology

Page 128 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0801548712499 42.3621050405824 (42.3621050405824, - http://www.godaddy.com 71.0801548712499) -71.0805992117041 42.3652581293824 (42.3652581293824, - http://sigilon.com/ 71.0805992117041) -71.0848274465445 42.362543834575 (42.362543834575, - https://immuneering.com/contact/ 71.0848274465445) -71.1141594186898 42.3633191631470 (42.363319163147096, - http://www.goodstartgenetics.com 96 71.1141594186898) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://alxerion.com/ 71.0787234936367) -71.0867113255645 42.3718022030206 (42.3718022030206, - http://plugcambridge.com/ 71.0867113255645) -71.1018787793074 42.3606516160272 (42.3606516160272, - http://www.agios.com 71.1018787793074) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.daedalussoftware.com 71.0838266372968) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.hopewell-tx.com/ 71.09491617478) -71.1459500611312 42.3946110167458 (42.3946110167458, - http://www.vertica.com 71.1459500611312) -71.1102284659553 42.3545195799064 (42.3545195799064, - http://www.bostonbiomedical.com/ 71.1102284659553) -71.09491617478 42.3619392706752 (42.3619392706752, - https://braizon.com/en/ 71.09491617478) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://myomo.com/ 71.0838266372968)

Page 129 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

4 79 8 276 272

4 79 8 253 89

5 88 3 280 145

13 82 5 196 412

4 79 8 276 154

4 60 8 186 999

11 117 4 265 123

4 79 8 277 295

7 83 1 258 86

6 3 13 168 1098

11 114 4 178 101

7 83 1 258 86

4 79 8 277 295

Page 130 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Quintara Biosciences 625 Mt. Auburn Street Cambridge MA

Moderna Therapeutics 200 Technology Square Cambridge MA

BlueRock Therapeutics One Broadway Cambridge MA

Cellay, Inc. 100 Inman Street Cambridge MA

Biogen Idec 225 Binney Street Cambridge MA

Rome Therapeutics 700 Main Street Cambridge MA

Strategic Science & Technologies 58 Charles Street Cambridge MA

X4 Pharmaceuticals 955 Massachusetts Avenue Cambridge MA

Philips Research 2 Canal Park Cambridge MA

SynDevRx One Broadway Cambridge MA

Amgen, Inc. 360 Binney Street Cambridge MA

Alnylam Pharmaceuticals 300 Third Street Cambridge MA

Triplet Therapeutics One Kendall Square Cambridge MA

Page 131 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02138 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02141 Biotechnology Life Science

02139 Biotechnology Life Science

02141 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Biotechnology Life Science

Page 132 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

 DNA sequencing and genomic services 2005

R&D in novel therapeutics 2010

Developer of induced pluripotent stem cell (iPSC) therapies 2016

Drug Development 2009

Drug R&D and Manufacturing 1978

Cancer therapeutics company 2020

Development of topical formulations

R&D in novel therapeutics 2016

R&D in lighting and healthcare technology 1914

Drug Development 2007

R&D in human therapeutics 1980

Uses RNA interface for new drug discovery 2002

Drug development 2019

Page 133 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.1471445054796 42.3753758794434 (42.3753758794434, - https://www.quintarabio.com/ 71.1471445054796) -71.0912149614735 42.3629219468234 (42.3629219468234, - http://www.modernatx.com/ 71.0912149614735) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://bluerocktx.com/ 71.0838266372968) -71.1015788078025 42.3718698253958 (42.3718698253958, - http://www.cellayinc.com 71.1015788078025) -71.08567301266 42.3662549989373 (42.3662549989373, - https://www.biogen.com/en_us/contact.h 71.08567301266) tml -71.09491617478 42.3619392706752 (42.3619392706752, - https://rometx.com/ 71.09491617478) -71.079680757493 42.3672963253637 (42.3672963253637, - http://www.strategicscience.com/ 71.079680757493) -71.1099256678971 42.3690189046948 (42.3690189046948, - http://www.x4pharma.com/ 71.1099256678971) - 42.3700645210408 (42.3700645210408, - http://www.research.philips.com/ 71.0763151655322 9 71.07631516553229) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.syndevrx.com 71.0838266372968) -71.0901747711236 42.3664369853085 (42.3664369853085, - http://www.amgen.com 71.0901747711236) -71.0823294451049 42.3654975793537 (42.3654975793537, - http://www.alnylam.com/ 71.0823294451049) -71.0903221519948 42.3672909799538 (42.3672909799538, - http://www.triplettx.com/ 71.0903221519948)

Page 134 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

2 36 12 62 677

7 87 1 258 398

4 79 8 277 295

10 55 6 221 853

4 71 8 252 424

7 83 1 258 86

4 71 8 117 33

10 64 6 113 159

4 65 8 226 19

4 79 8 277 295

3 73 7 258 68

4 79 8 135 89

3 73 7 258 68

Page 135 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Editas Medicine 11 Hurley Street Cambridge MA

Combined Therapeutics 700 Main Street Cambridge MA

Manus Biosynthesis 1030 Massachusetts Avenue Cambridge MA

Fraunhofer Heinrich Hertz Institute 25 First Street Cambridge MA

Gemini Therapeutics, Inc. 300 One Kendall Square Cambridge MA

TriNetX 125 CambridgePark Drive Cambridge MA

Fairbanks Pharmaceuticals 700 Main Street Cambridge MA

iZotope 60 Hampshire Street Cambridge MA

Rx Celerate One Broadway Cambridge MA

Modalis Therapeutics 51 Moulton Street Cambridge MA

Halifax Biomedical One Broadway Cambridge MA

Relay Therapeutics 399 Binney Street Cambridge MA

Smart Labs 21 Erie Street Cambridge MA

Page 136 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02141 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02141 Nonprofit/R&D Academic/Non-Profit

02142 Biopharmaceutical Life Science

02140 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Information Technology High Tech

02142 Contract Research Life Science

02138 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Incubator Coworking

Page 137 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

R&D in genome editing 2013

Pre-clinical-stage immunotherapy biotech 2016

2011

Research Lab focusing on Technology 2011

Precision medical company 2015

Clinical research

Develop diabetes therapies 2014

Audio Technology 2001

Outsourced drug development platform

Develops therapeutics using CRISPR

R&D orthopedic diagnostic company

Analyzes the movement of proteins 2016

Lab Incubator Space 2015

Page 138 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

71.0903221519948)

-71.0783143490886 42.36817412814 (42.36817412814, - http://editasmedicine.com/index.php 71.0783143490886) -71.09491617478 42.3619392706752 (42.3619392706752, - http://www.combinedtx.com/ 71.09491617478) -71.1122045152113 42.3695906454501 (42.3695906454501, - https://www.manusbio.com/index.php 71.1122045152113) -71.0772857119759 42.3696017222785 (42.3696017222785, - http://www.hhi.fraunhofer.de 71.0772857119759) -71.0909213544418 42.3661335993384 (42.3661335993384, - https://geminitherapeutics.com/ 71.0909213544418) -71.1457538393149 42.3950752907362 (42.3950752907362, - http://trinetx.com/ 71.1457538393149) -71.09491617478 42.3619392706752 (42.3619392706752, - http://www.fairbankspharma.com/ 71.09491617478) -71.0930790984057 42.3670007673897 (42.3670007673897, - http://www.izotope.com 71.0930790984057) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.rxcelerate.com/ 71.0838266372968) -71.1489984332958 42.391159555635 (42.391159555635, - https://www.modalistx.com/en/ 71.1489984332958) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://halifaxbiomedical.com/ 71.0838266372968) -71.0902337857325 42.3676019682682 (42.3676019682682, - http://relaytx.com/ 71.0902337857325) -71.1038053210519 42.3578097131557 (42.3578097131557, - http://www.massinnovationlabs.com/#ho

Page 139 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

4 57 8 112 152

7 83 1 258 86

13 66 5 110 166

4 57 8 226 151

3 73 7 258 68

6 3 13 168 1098

7 83 1 258 86

7 70 1 124 168

4 79 8 277 295

1 9 10 244 740

4 79 8 277 295

3 61 7 117 723

11 117 4 147 124

Page 140 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Cellaria Biosciences 675 West Kendall Street Cambridge MA

Tevard Biosciences 700 Main Street Cambridge MA

Compass Therapeutics 245 First Street Cambridge MA

Microsoft New England Research & Development Center One Memorial Drive Cambridge MA

Elicio Therapeutics One Kendall Square Cambridge MA

InTeahouse 727 Massachusetts Avenue Cambridge MA

Intrepid Pursuits 222 Third Street Cambridge MA

Vedanta Biosciences 19 Blackstone Street Cambridge MA

Arbor Biotechnologies 790 Memorial Drive Cambridge MA

Euretos One Broadway Cambridge MA

Aviceda Therapeutics One Broadway Cambridge MA

Hunterian Medicine 100 Pacific Street Cambridge MA

Page 141 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Space/Incubator

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Information Technology High Tech

02142 Biotechnology Life Science

02139 Incubator Coworking Space/Incubator 02141 Information Technology High Tech

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

Page 142 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Cell Model Development

Gene therapy 2017

Drug Development 2015

Software/Application Development 2008

Immuno-tumor vaccine developer

Incubator Space 2015

Digital Production 2010

Drug development

Early stage life sciences company 2016

Bioinformatics 2012

Developer of glyco-immune therapeutics (GCT’s) 2018

Gene editing 2016

Page 143 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

71.1038053210519) http://www.massinnovationlabs.com/#ho me -71.0819311032568 42.3646274397156 (42.3646274397156, - https://www.cellariabio.com/ 71.0819311032568) -71.09491617478 42.3619392706752 (42.3619392706752, - 71.09491617478) -71.0787234936367 42.3635391601232 (42.3635391601232, - https://www.compasstherapeutics.com/c 71.0787234936367) ontact/ -71.0812562847235 42.3613569943424 (42.3613569943424, - http://www.microsoftcambridge.com 71.0812562847235) -71.0903221519948 42.3672909799538 (42.3672909799538, - https://elicio.com/ 71.0903221519948) -71.1048992735392 42.3662928902631 (42.3662928902631, - http://www.inteahouse.com/ 71.1048992735392) -71.0809909801686 42.3670782746947 (42.3670782746947, - http://www.intrepid.io/ 71.0809909801686) -71.1145004232591 42.3634172936065 (42.3634172936065, - http://www.vedantabio.com/ 71.1145004232591) -71.1148317990337 42.3598764519961 (42.3598764519961, - https://arbor.bio/ 71.1148317990337) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.euretos.com/euretos 71.0838266372968) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://www.avicedarx.com/ 71.0838266372968) -71.1034926737103 42.3607198649548 (42.3607198649548, - http://hunterian.com/

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4 79 8 276 154

7 83 1 258 86

4 79 8 276 154

5 84 3 180 149

3 73 7 258 68

10 75 6 264 52

4 71 8 117 33

13 82 5 196 412

11 20 4 243 42

4 79 8 277 295

4 79 8 277 295

11 117 4 147 469

Page 145 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Leap Therapeutics 47 Thorndike Street Cambridge MA

Torque One Kendall Square Cambridge MA

Sony DADC Biosciences One Mifflin Place Cambridge MA

Neutrolis 700 Main Street Cambridge MA

Momenta Pharmaceuticals, Inc. 301 Binney Street Cambridge MA

Ribon Therapeutics 35 Cambridge Park Drive Cambridge MA

Seaside Therapeutics 840 Memorial Drive Cambridge MA

Johnson and Johnson Innovation Center 255 Main Street Cambridge MA

Korro Bio 400 Technology Square Cambridge MA

QurAlis 700 Main Street Cambridge MA

Cytel, Inc. 675 Massachusetts Avenue Cambridge MA

Shell TechWorks 101 Main Street Cambridge MA

Page 146 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02141 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02138 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02140 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Information Technology High Tech

02142 Biotechnology Life Science

Page 147 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Clinical-stage biopharmaceutical company

R&D in immunotherapy

OEM Supplier 1986

Developing therapeutics that target neutrophils 2017

Drug Development 2001

Discovery and development of monoPARP inhibitors 2015

R&D in neuro-developmental disorders 2011

R&D in novel early-stage collaborations with emerging companies 2013

Precision genetic medicine

Drug discovery and development 2016

Statistical Software Development 1987

Innovation Center 2014

Page 148 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

71.1034926737103)

-71.0795405331677 42.3698974797414 (42.3698974797414, - http://www.leaptx.com/ 71.0795405331677) -71.0903221519948 42.3672909799538 (42.3672909799538, - http://www.torquetx.com/ 71.0903221519948) -71.1224787776923 42.3732988725555 (42.3732988725555, - http://biosciences.sonydadc.com/ 71.1224787776923) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.neutrolis.com/ 71.09491617478) -71.0879679450326 42.3665842178827 (42.3665842178827, - http://www.momentapharma.com 71.0879679450326) -71.1435428235516 42.3948130745936 (42.3948130745936, - http://ribontx.com/ 71.1435428235516) -71.1150750377726 42.3631052107115 (42.3631052107115, - http://www.seasidetherapeutics.com/ 71.1150750377726) -71.0851730353328 42.3624974409972 (42.3624974409972, - http://www.jnjinnovation.com/global- 71.0851730353328) innovation-centers/boston -71.091951377916 42.3638464323303 (42.3638464323303, - http://www.korrobio.com/ 71.091951377916) -71.09491617478 42.3619392706752 (42.3619392706752, - https://quralis.com/ 71.09491617478) -71.1040820735933 42.3658127184955 (42.3658127184955, - http://www.cytel.com 71.1040820735933) -71.0815834855672 42.3622099312421 (42.3622099312421, - http://www.shell.com/global/future- 71.0815834855672) energy/innovation/innovate-with-

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4 57 8 187 31

3 73 7 258 68

12 103 12 197 531

7 83 1 258 86

4 71 8 117 310

6 3 13 168 1007

13 82 5 241 322

5 88 3 280 145

7 87 1 258 217

7 83 1 258 86

10 75 6 264 378

4 79 8 276 272

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Hopper 275 Third Street Cambridge MA

Whitehead Institute for Biomedical Research 455 Main Street Cambridge MA

Alexandria LaunchLabs One Kendall Square Cambridge MA

Kytopen 501 Massachusetts Ave Cambridge MA

Centogene 99 Erie Street Cambridge MA

Clear Creek Bio 585 Massachusetts Avenue Cambridge MA

Readcoor 840 Memorial Drive Cambridge MA

Ultivue 763D Concord Ave Cambridge MA

Praxis Precision Medicines One Broadway Cambridge MA

MOMA Therapeutics 215 First Street Cambridge MA

Neon Therapeutics 40 Erie Street Cambridge MA

Celgene Avilomics Research 200 CambridgePark Drive Cambridge MA

Page 151 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Information Technology High Tech

02142 Academic/Nonprofit R&D Academic/Non-Profit

02142 Incubator Coworking Space/Incubator

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Medical Devices Life Science

02138 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02140 Biopharmaceutical Life Science

Page 152 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Flight-booking app 2007

Lab-Research and Development 1982

Incubator/Coworking space for seed and early-stage life science companies 2019

Research Products and Instrumentation 2017

Human genetics analysis 2006

Drug development for infectious disease and cancer

Medical Devices for panomic spatial sequencing

Human Diagnostic Development

Drug development

Drug discovery 2020

Cancer Immunology Research 2015

R&D in drug therapy

Page 153 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

shell/shell-techworks.html -71.0824231132301 42.3659989260598 (42.3659989260598, - http://www.hopper.com/ 71.0824231132301) -71.0896300928097 42.3630372323129 (42.3630372323129, - http://www.wi.mit.edu/ 71.0896300928097) -71.0911051057089 42.3663645885345 (42.3663645885345, - https://www.alexandrialaunchlabs.com/c 71.0911051057089) ambridge -71.1014931241571 42.3642623755098 (42.3642623755098, - http://kytopen.com/ 71.1014931241571) -71.1055206894536 42.3588440982339 (42.3588440982339, - http://www.centogene.com/ 71.1055206894536) -71.1027812952324 42.3650344370028 (42.3650344370028, - https://www.clearcreekbio.com/ 71.1027812952324) -71.1150750377726 42.3631052107115 (42.3631052107115, - https://www.readcoor.com/ 71.1150750377726) -71.1528283444272 42.3925467275244 (42.3925467275244, - https://www.ultivue.com/ 71.1528283444272) -71.0838266372968 42.3626255873632 (42.3626255873632, - https://www.praxismedicines.com 71.0838266372968) -71.0785437379441 42.3642063517586 (42.3642063517586, - https://momatx.com/ 71.0785437379441) -71.1042275993795 42.3574194822637 (42.3574194822637, - http://neontherapeutics.com/ 71.1042275993795) -71.1489061819435 42.3954009280417 (42.3954009280417, - https://www.celgene.com/research- 71.1489061819435) development/rd-locations/avilomics-

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4 71 8 117 143

5 88 3 279 255

3 73 7 258 68

7 80 1 264 22

11 117 4 151 184

7 80 1 264 381

13 82 5 241 322

1 8 10 289 1066

4 79 8 277 295

4 79 8 276 318

11 114 4 147 481

6 3 13 168 1098

Page 155 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Mother Dirt One Broadway Cambridge MA

nference One Main Street Cambridge MA

Resilient Systems 75 Binney Street Cambridge MA

Genovis 245 First Street Cambridge MA

Astrocyte Pharmaceuticals, Inc. 245 First Street Cambridge MA

Energy Savvy One Broadway Cambridge MA

Yumanity Therapeutics 790 Memorial Drive Cambridge MA

Quench Bio 400 Technology Square Cambridge MA

Lytica Therapeutics 700 Main Street Cambridge MA

BeiGene 55 Cambridge Parkway Cambridge MA

Kintai Therapeutics 26 Landsdowne Street Cambridge MA

CRISPR Therapeutics 610 Main Street Cambridge MA

Page 156 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02142 Biotechnology Life Science

02142 Biotechnology High Tech

02142 Information Technology High Tech

02142 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02142 Clean Technology Clean Energy

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biopharmaceutical Life Science

Page 157 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Skin products 2015

AI technology 2015

IBM Security Platform

Drug development for brain injury patients 2014

Energy Data Management 2008

Drug discovery in neurogenerative disease 2014

Developing medicines for severe inflammatory diseases 2018

Developer of peptide therapeutics

Global, commercial-stage biotechnology company 2010

Precision therapeutics 2016

Development in genome-editing technology 2013

Page 158 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

research/ -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.motherdirt.com/ 71.0838266372968) -71.0801548712499 42.3621050405824 (42.3621050405824, - http://nference.ai 71.0801548712499) -71.0805066509211 42.3657792656652 (42.3657792656652, - https://www.resilientsystems.com/ 71.0805066509211) -71.0787234936367 42.3635391601232 (42.3635391601232, - https://www.genovis.com 71.0787234936367) -71.0787234936367 42.3635391601232 (42.3635391601232, - https://www.astrocytepharma.com/ 71.0787234936367) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.energysavvy.com/ 71.0838266372968) -71.1148317990337 42.3598764519961 (42.3598764519961, - http://yumanity.com/ 71.1148317990337) -71.091951377916 42.3638464323303 (42.3638464323303, - https://quenchbio.com/ 71.091951377916) -71.09491617478 42.3619392706752 (42.3619392706752, - https://lyticatherapeutics.com/ 71.09491617478) -71.0762977105578 42.3657420050532 (42.3657420050532, - https://www.beigene.com/ 71.0762977105578) -71.0990223853639 42.3610129940534 (42.3610129940534, - http://www.kintaitx.com/ 71.0990223853639) -71.0940133114707 42.3628809096634 (42.3628809096634, - http://crisprtx.com/ 71.0940133114707)

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4 79 8 277 295

4 79 8 276 272

4 71 8 254 144

4 79 8 276 154

4 79 8 276 154

4 79 8 277 295

11 20 4 243 42

7 87 1 258 217

7 83 1 258 86

4 65 8 218 153

11 117 4 265 239

7 83 1 258 299

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Nimbus Therapeutics 130 Prospect Street Cambridge MA

Nest Bio Labs 325 Vassar Street Cambridge MA

Mount Auburn Hospital 330 Mount Auburn Street Cambridge MA

Apple One Broadway Cambridge MA

Surface Oncology 50 Hampshire Street Cambridge MA

Akamai 150 Broadway Cambridge MA

IDDI Inc. 185 Alewife Brook Pkwy Cambridge MA

Ipsen Biosciences 650 East Kendall St Cambridge MA

Arkuda Therapeutics 400 Technology Square Cambridge MA

BioDevek 700 Main Street Cambridge MA

Amazon 101 Main Street Cambridge MA

ReviveMed 245 First Street Cambridge MA

Novogy 85 Bolton Street Cambridge MA

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02139 Biopharmaceutical Life Science

02139 Incubator Coworking Space/Incubator 02138 Nonprofit/R&D Academic/Non-Profit

02142 Information Technology High Tech

02139 Biopharmaceutical Life Science

02142 Information Technology High Tech

02138 Contract Research Life Science

02142 Biotechnology High Tech

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Information Technology High Tech

02142 Biotechnology Life Science

02140 Biotechnology Life Science

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R&D in computer-based drug discovery

Incubator Space for life science companies

Hospital 1886

Product and Software Development 1976

R&D in cancer immunotherapies 2015

Software/Internet Applications 1995

Clinical Research Development 1991

R&D in therapies and peptides

Neurodegenerative disease therapy development

Medical device company

Online shopping, shipping, and software company 1994

Precision-medicine platform 2018

Agricultural biotechnology 2009

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-71.1014841337959 42.3684261599883 (42.3684261599883, - http://www.nimbusdiscovery.com 71.1014841337959) -71.1056951550591 42.3549339189278 (42.3549339189278, - https://nest.bio/ 71.1056951550591) -71.1358492006121 42.3746053090362 (42.3746053090362, - http://www.mountauburnhospital.org/ 71.1358492006121) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://www.apple.com 71.0838266372968) -71.092829191189 42.3668780444442 (42.3668780444442, - https://www.surfaceoncology.com/ 71.092829191189) -71.088689669712 42.3643142391919 (42.3643142391919, - http://www.akamai.com 71.088689669712) -71.142276992259 42.3904955493343 (42.3904955493343, - https://www.iddi.com/ 71.142276992259) -71.0810729236616 42.3645257329026 (42.3645257329026, - https://www.ipsenus.com/ 71.0810729236616) -71.091951377916 42.3638464323303 (42.3638464323303, - https://www.arkudatx.com/ 71.091951377916) -71.09491617478 42.3619392706752 (42.3619392706752, - 71.09491617478) -71.0815834855672 42.3622099312421 (42.3622099312421, - http://www.amazon.com 71.0815834855672) -71.0787234936367 42.3635391601232 (42.3635391601232, - http://revive-med.com 71.0787234936367) -71.1305699529474 42.39003115429 (42.39003115429, - http://novogyinc.com 71.1305699529474)

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7 69 1 116 327

5 85 3 160 125

12 46 12 174 544

4 79 8 277 295

7 70 1 258 168

5 88 3 279 255

1 9 10 246 1022

4 79 8 276 154

7 87 1 258 217

7 83 1 258 86

4 79 8 276 272

4 79 8 276 154

8 97 2 16 727

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Cambridge MedSpace 705 Cambridge Street Cambridge MA

DropWise Technologies 1035 Cambridge Street Cambridge MA

Workbar Cambridge 45 Prospect Street Cambridge MA

Surgicure Technologies 77 Massachusetts Ave Cambridge MA

Ymir Genomics 700 Main Street Cambridge MA

Evelo Biosciences 620 Memorial Drive Cambridge MA

Double Rainbow Biosciences 840 Memorial Drive Cambridge MA

Anida Pharma Inc. 155 Brookline Street Cambridge MA

Schlumberger-Doll Research One Hampshire Street Cambridge MA

Collaborative Trajectory Analysis Project One Broadway Cambridge MA

Neuroelectrics 210 Broadway Cambridge MA

FerGene 245 Main Street Cambridge MA

Tango Therapeutics 100 Binney Street Cambridge MA

Page 166 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

02141 Coworking Space Coworking Space/Incubator 02141 Biotechnology Life Science

02139 Coworking Space Coworking Space/Incubator 02142 Biotechnology High Tech

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02139 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02142 Information Technology High Tech

02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biotechnology Life Science

02142 Biopharmaceutical Life Science

Page 167 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Coworking space for Med Device companies 2016

Manufacturer of coating technology

Flexible coworking space 2013

Medical tube development 2018

Diagnostics and therapeutics 2011

Drug Development in oncobiotic therapeutics

Preclinical-stage biopharmaceutical companyÂ

Software Development 1948

Duchenne drug development 2015

Digital Brain Health

Drug development 2020

Drug Development

Page 168 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0883548692668 42.3722047219566 (42.3722047219566, - https://www.cambridgemedspace.com/ 71.0883548692668) -71.0937041519439 42.3734936331323 (42.3734936331323, - http://www.drop-wise.com/ 71.0937041519439) -71.1033520858018 42.3662852541362 (42.3662852541362, - 71.1033520858018) -71.0933394249692 42.3591282547599 (42.3591282547599, - https://www.surgicuretech.com/ 71.0933394249692) -71.09491617478 42.3619392706752 (42.3619392706752, - http://www.ymirgenomics.com/ 71.09491617478) -71.1076001591032 42.3539087777099 (42.3539087777099, - http://evelobio.com/#new-page 71.1076001591032) -71.1150750377726 42.3631052107115 (42.3631052107115, - https://www.doublerainbowbio.com/ 71.1150750377726) -71.1052534598514 42.3601157807063 (42.3601157807063, - https://www.anidapharma.com/ 71.1052534598514) -71.0900645228903 42.3652324408355 (42.3652324408355, - http://www.slb.com 71.0900645228903) -71.0838266372968 42.3626255873632 (42.3626255873632, - http://ctap-duchenne.org 71.0838266372968) -71.0932182826967 42.3661132632655 (42.3661132632655, - http://www.neuroelectrics.com/ 71.0932182826967) -71.0848274465445 42.362543834575 (42.362543834575, - https://www.fergene.com/ 71.0848274465445) -71.0805992117041 42.3652581293824 (42.3652581293824, - https://www.tangotx.com/ 71.0805992117041)

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3 50 7 186 742

3 48 7 191 900

10 75 6 264 378

5 90 3 271 6

7 83 1 258 86

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13 82 5 241 322

11 110 4 146 285

3 73 7 258 68

4 79 8 277 295

7 77 1 130 63

5 88 3 280 145

4 79 8 253 89

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Kayak 10 Canal Park Cambridge MA

HiFiBio 237 Putnam Ave Cambridge MA

Amylyx Pharmaceutical 43 Thorndike Street Cambridge MA

Dicerna Pharmaceuticals 87 CambridgePark Drive Cambridge MA

HelixNano 700 Main Street Cambridge MA

Werewolf Therapeutics 1030 Massachusetts Avenue Cambridge MA

Sea Pharmaceuticals 14 Gray Street Cambridge MA

Cedilla Therapeutics 38 Sidney Street Cambridge MA

LifeMine Therapeutics 300 Technology Square Cambridge MA

Akriveia Therapeutics 610 Main Street Cambridge MA

Vericel 64 Sidney Street Cambridge MA

AstraZeneca Neuroscience iMed 141 Portland Street Cambridge MA

Acrivon Therapeutics 700 Main Street Cambridge MA

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02141 Information Technology High Tech

02139 Biopharmaceutical Life Science

02141 Biopharmaceutical Life Science

02140 Biopharmaceutical Life Science

02139 Biotechnology Life Science

02139 Biotechnology Life Science

02138 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02142 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02139 Biopharmaceutical Life Science

02139 Biotechnology Life Science

Page 172 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Online travel company 2004

Drug development in droplet-based microfluidics

IND-enabling stage pharmaceutical company

R&D in liver and genetically defined cancers 2007

R&D DNA nanotechnology

Oncology biotherapeutics company

R&D in neurological therapeuticss 2013

R&D in cancer and other diseases caused by protein dysregulation.

Drug Development 2016

R&D in the next generation of cancer immunotherapies 2015

R&D in patient-specific cellular therapies with severe diseases and conditions 1989

R&D hub around neuroscience

Drug development 2018

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-71.0754827280311 42.3687255062399 (42.3687255062399, - http://www.kayak.com/ 71.0754827280311) -71.1141594186898 42.3633191631470 (42.363319163147096, - http://www.hifibio.com/ 96 71.1141594186898) -71.0792334051895 42.3696277325763 (42.3696277325763, - https://www.amylyx.com/ 71.0792334051895) -71.1447354193478 42.3954676435594 (42.3954676435594, - http://dicerna.com/ 71.1447354193478) -71.09491617478 42.3619392706752 (42.3619392706752, - https://www.helixnano.com/ 71.09491617478) -71.1122045152113 42.3695906454501 (42.3695906454501, - https://werewolftx.com/ 71.1122045152113) -71.1219457769937 42.3830302920322 (42.3830302920322, - 71.1219457769937) -71.1009023296914 42.3615643305096 (42.3615643305096, - https://www.cedillatx.com/ 71.1009023296914) -71.0917711454075 42.3634083285031 (42.3634083285031, - http://www.lifeminetx.com 71.0917711454075) -71.0940133114707 42.3628809096634 (42.3628809096634, - http://www.akriveiatx.com/ 71.0940133114707) -71.101491087057 42.3610154814174 (42.3610154814174, - http://vcel.com/ 71.101491087057) -71.0922963004345 42.365576593007 (42.365576593007, - https://azneuro.com/about-us/ 71.0922963004345) -71.09491617478 42.3619392706752 (42.3619392706752, - 71.09491617478)

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4 65 8 226 14

13 82 5 196 412

4 57 8 187 31

6 3 13 168 1098

7 83 1 258 86

13 66 5 110 166

8 23 2 35 658

11 117 4 265 487

7 87 1 258 217

7 83 1 258 299

11 117 4 265 244

7 77 1 258 134

7 83 1 258 86

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TiE Boston 101 Main Street Cambridge MA

HIS CERA 55 Cambridge Parkway Cambridge MA

Industry Lab 288 Norfolk Street Cambridge MA

Anelixis Therapeutics 300 Technology Square Cambridge MA

Comet Therapeutics 700 Main Street Cambridge MA

Cyclerion Therapeutics 301 Binney Street Cambridge MA

Pathfinder Cell Therapy 12 Bow Street Cambridge MA

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02142 Non-Profit Academic/Non-Profit

02142 Clean Technology Clean Energy

02139 Coworking Space Coworking Space/Incubator 02142 Biotechnology Life Science

02139 Biotechnology Life Science

02142 Biopharmaceutical Life Science

02138 Biotechnology Life Science

Page 177 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

Supports Entrepreneurship 1992

Energy research

Flexible coworking space

Facilitates pre-clinical drug development 2012

CoEnzyme A (CoA) science and intermediate metabolism 2018

Clinical-stage biopharmaceutical company

Develops therapies for organ-specific cell damage

Page 178 of 180 09/25/2021 Life Sciences and Technology Company Listing: September 2020

-71.0815834855672 42.3622099312421 (42.3622099312421, - https://boston.tie.org/ 71.0815834855672) -71.0762977105578 42.3657420050532 (42.3657420050532, - 71.0762977105578) -71.097265419591 42.3712957612243 (42.3712957612243, - http://industry-lab.com/ 71.097265419591) -71.0917711454075 42.3634083285031 (42.3634083285031, - http://www.anelixistherapeutics.com/ 71.0917711454075) -71.09491617478 42.3619392706752 (42.3619392706752, - https://comettherapeutics.com/ 71.09491617478) -71.0879679450326 42.3665842178827 (42.3665842178827, - https://www.cyclerion.com/ 71.0879679450326) -71.1155196205337 42.371740211738 (42.371740211738, - http://www.pathfindercelltherapy.com/ 71.1155196205337)

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4 65 8 218 153

3 54 7 221 730

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13 107 5 230 932

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