The NIH Record U.S. Department November27 National of Health, 1979 Institutes Education, and Vol. XXXI of Welfare No.24 Health

Dr. Walter Gilbert, NIH'ers Ride Bikes Lasker Award Winner, To Deliver NIH Lecture To Save Energy Tomorrow And Money

Dr. Walter Gilbert, who will deliver the NIH Rising gasoline prices and the initiation of Lecture tomorrow (Wednesday, Nov. 28) at parking fees in November have spurred NIH 8:15 p.m. in the Masur Auditorium, has employees to find alternate ways of getting received two prestigious awards this month. to and from work. Over the past 6 months, He was awarded an Albert Lasker medical employees have turned to the bicycle as a research prize on Nov. 14, and the Gairdner way to beat the additional expense of trans­ portation, to help save on energy, and to Foundation Award-Canada's highest award in medical science-on Nov. 2. improve their health. Dr. Gilbert, professor of molecular biology On Nov. 7, 150 employees heard NIH at Harvard University, and Dr. Frederick Director Dr. Donald S. Fredrickson, Mont­ Sanger of Britain shared the $1 5,000 Lasker gomery County transportation officials, and prize for their studies on the chemical makeup representatives of the M aryland-National Park of DNA. and Planning Commission speak on the development of the bikeway system for NIH A pioneer in developing an understanding and the surrounding area. of the molecular basis of cellular regulation, Dr. Gilbert has been a longtime grantee of The meeting marked the first time a Federal the National Institute of General Medical organization solicited help from Montgomery Sciences, and is also receiving support from County to assist bicyclists. NIH is the largest the National Institute of Arthritis, Metabolism, Or. Gilbert will speak on The Structure and (See BIKES, Page 4) and Digestive Diseases. Evolution of Genes.

NCI Scientists Attend lnternat'I Symposium In USSR on Leukemia Research

By Pat Newman the only primate research center in the USSR, boasts the largest collection of baboons in Ten NCI scientists recently made the 2-day captivity in the world. trip to , a small resort on the in Soviet , to join nearly 300 sci­ During opening ceremonies of this first entists from 16 western countries and the cancer meeting to be held in that part of the USSR at the IXth International Symposium on world, Dr. Emil J. Freireich, head of the Comparative Research on Leukemia and department of developmental therapeutics at Related Diseases. M.D. Anderson Hospital and Tumor Institute Papers covered such diverse topics as cell in Houson, Tex., received the 12th biennial differentiation, expression of host and viral DeVilliers Award from The Leukemia Society genes, immunology, the role of herpesviruses of America, Inc. The award, which included a in primate and human lymphomas, and the plaque and $1,000, cited Dr. Freireich's epidemiology, diagnosis, and treatment of advocacy of intensive therapy for leukemia leukemia and lymphomas in humans. patients. Pat Newman an NCI science writer, who Dr. Harvey Rabin of the NCI Frederick attended the m'eeting, also had an opportunity Cancer Research Center summarized joint to visit several cancer laboratories in Moscow. virus research by scientists from the Institute, the FCRC, and other U.S. labora­ Pitsunda, is located north of Sukhumi, the tories. Although several viruses have been capital of , one of two autonomous Georgian Soviet Socialist Republics. It is isolated from a 900-animal baboon colony at the home of the Institute of Experimental Sukhumi, including a baboon RNA type-C virus, one of the most interesting viruses Pathology and Therapy, whose scientific staff is Herpesvirus papio, named after the Hamadryas Or. Fredrickson starts out for a noon-hour ride collaborates in leukemia and lymphoma re­ after taking his bicycle from a bike rack ne.u search with scientists in the U.S. The Institute, (See SYMPOSIUM, Page 8) his office.-Photo by Ga,y Best. CFC Campaign Deadline- Extended

The NIH Record NIH CFC Contributions as of November 9th Publi

Free Clinic Needs Volunteers A bar graph shows the amount of CFC donations that have been collected from each ln~ifute as of Nov. 9, Substantial donations have been received since that date, say officials. These additional dona­ The Bache Memurial Free Clinic needs tions indicate that many NIH'ers have responded to the call to be a good neighbor. If you have not yet volunteer physicians, nurses, laboratory tech­ conlributed, please contact your keyworker before the end of the drive on Friday, Dec. 7. nicians, and college students. The clinic, also known as the Bethesda Free Clinic, is located at St. John's Episcopal Privacy Act Requirements To Be Discussed Church in Chevy Chase, Md. It seives as a treatment center for venereal disease, con­ At Meeting traception, and minor ailments. The clinic is also a diagnostic and referral center for more A panel of HEW officials will visit Nill to Administration; a.rid RichMd to NIH employees. All former NIH employees who have retired Offers Varied Courses Any employee who has not received this are invited to attend the first organizational material should contact the B/1/D personnel A free schcdu!e of winter courses is avail­ meeting of the NIH Recreation & Welfare able from the Graduate School, USDA. office. Association Retirees' Club on Wednesday. Dec. 5, from 2 to 4 p.m., in Bldg. 31, Conf. The schedule includes hundreds of day, Burglary Information Rm. 7. This room is located on the 6th floor evening, and correspondence courses in job­ Is Needed by Police of the C wing. related and leisure subjects. The R&W is laying the groundwork for Courses offered this winter include The Montgomery County Police are seek­ getting the retirees invo!ved with NIH long accounting, computer sciences, management, ing information regarding a burglary which after their working days are over. typing, shorthand, paralegalism, journalism, took place on Oct. 23, between 7-9 p.m., at An R&W official says, "We feel that retire­ graphic arts, photography, and more. a home on the 5000 block of Cedar Lane. ment is the beginning of a new life_ It should Registration for evening courses will be Approximately $60,000 worth of valuables be a shift away from employment to other were stolen. Police say that the burglars activities, learning new skills, providing held Jan. 2-5 in the USDA Patio, North Admin­ entered the home by kicking in !he front door. guidance and enjoying each other. istration Bldg., 14th St. and Independence If you have any information, call Officer "We hope to gain insight into your wants Ave., S.W., Washington, D.C. Susan Raymund of the Munlgomery County and desires, w!1ether it be travel, recreational For further information and a schedule of Police at 652-9200. clubs, or volunteerism-we want to help you." classes, call 447-4419.

Page2 The NIH Record November 27, 1979 Dr. Jakubczak Joins Empty I.V. Bottles Discarded by Clinical Center Expanded NIA Program Used To Save Lives in Bangladesh Dr. Leonard F. Jakubczak, a former NIH The garage sale slogan, "One person's trash is another person's treasure," takes on a Grants Associate with an extensive back­ ground in clinical and experimental psy­ unique meaning at NIH. chology, has joined the National Institute on Recently, 20,000 used intravenous fluid Aging's recently expanded social and be­ bottles discarded by the Clinical Center were havioral research program headed by Dr. shipped to Dacca, Bangladesh, where they are Matilda White Riley. He will be responsible being used to save the lives of cholera victims. for stimulating research on the cognitive, perceptual, and psychomotor processes. In February, Dr. Carl Miller, Enteric Dis­ eases Program Officer, National Institute of Has Written Widely on Aging Allergy and Infectious Diseases, received an Dr. Jakubczak's appointment completes his urgent request for the bottles from the Inter­ transition from laboratory scientist to ad­ national Centre for Diarrhoeal Disease Re­ ministrator. Earlier in his career, he investi­ search in Dacca. The Centre, which was partly gated and published widely in the areas of supported by NIAID at the time, needed the dependency behavior; the behavioral aspects bottles to administer special I.V. fluids to of nutrition, aging, and longevity; and the dehydrated cholera victims who otherwise psychology of adult development. might die. Cholera, which causes intense diarrhea and vomiting, is endemic in Bangladesh. The deadline for collecting the bottles was A village mother gives her child oral saline for Aug. 1, because NIH support for the Centre diarrhea. The International Centre for Diarrhoeal would end soon after that date. Dr. Miller; Disease Research teaches the local population to Dr. Lloyd Herman, a microbiologist with the prepare and administer oral fluids so that less Division of Research Services; and Milton serious cases of diarrheal disease can be treated Gross, Ben Burritt, and William Brown, pack­ at home. Patients with serious illnesses such as ing and crating section, Division of Adminis­ cholera are taken to the hospital for I.V. treatment trative Services, went into high gear and salvaged 500 bottles per week from CC supplied about 450 bottles a week until the discards. order was filled at the end of July. When it became obvious in May that the On arrival in Dacca, the I.V. bottles are request for 20,000 bottles could not be filled cleaned, filled with a special salt solution, and by NIH alone, they enlisted the help of the sterilized so they will be ready when needed. nursing staff at Sibley Hospital. The hospital Each bottle can be recycled 15-20 times.

Birth Defects in Children of Alcoholic Mothers Directly Related to Alcohol

Scientific evidence has been presented for the direct effects of environmental agents on Or. Jakubczak's extensive experience in research the first time to indicate that birth defects in development. The embryos growing in cul­ at patient care centers has made him sensitive children of mothers who consume excessive ture can also be coupled with enzymes which to lhe needs of "bench scientists" and of patients, amounts of alcohol are directly related to an who are the end beneficiaries of research. activate indirect acting teratogens. effect of alcohol on the developing fetus, The studies by Dr. Brown, a visiting fellow A native of Buffalo, N.Y., Dr. Jakubczak without the confounding factors of altered in LDRT at the time of the studies, and Dr. received hi s bachelor's degree from St. maternal function, nutrition, or metabolism, Fabro, from the departments of pharmacology Joseph's College in Philadelphia, and his The experiments exposing rat embryos and O8-GYN at George Washington Uni­ master's degree from the University of growing in culture to ethanol were conducted versity, showed that both differentiation and Toronto. in the laboratory of Developmental and growth of embryos cultured in the presence He earned his Ph.D. from Washington Reproductive Toxicology at the National of ethanol (pure alcohol) were retarded as a University in St. Louis, where his dissertation Institute of Environmental Health Sciences. function of dosage. was under Dr. Robert Kleemeier, a pioneer in Investigators Ors. Nigel Brown, Eugenia H. The investigators, whose work was reported the psychosocial aspects of aging. Goulding, and Sergio Fabro are quick to in the Nov. 2, 1979, issue of Science, stated In 1962 Dr. Jakubczak won a competitive point out that the in vitro system supports that their observations suggest that the Fetal postdoctoral fellowship from the National the growth and development of the embryo Alcohol Syndrome may not be totally the Institute of Mental Health, where he studied in a manner that is indistinguishable from result of maternally produced metabolites or behavioral thermo-regulation and aging for growth and development within the womb. altered maternal function and that continuous 3 years with Dr. James E. Birren, the interna­ Dr. Robert L. Dixon, chief of LDRT, said exposure to high levels of ethanol exerts a tionally recognized scientist-administrator. the embryo culture is ideally suited to study direct toxic action on the developing embryo. The Veterans Administration Hospital in St. Louis then recruited Dr. Jakubczak to establish a gerontological psychology research 2-Volume Work To Assist Specialists in Communicative Disorders Available laboratory, which he directed from 1965 to 1978. Studies focused on environmental and MEDLINE Users Manual and Thesaurus for working in the fields of communicative physiological influences on behavior during Specialists in Communicative Disorders, 1979, science and disorders. maturity and old age. The results of these is available without charge from Dr. Christy investigations suggest that the ability to Ludlow, Communicative Disorders Program, It was designed to call MEDLINE to the regulate calories and body weight remains NINCDS, 7550 Wisconsin Ave., Rm. 1C-13, attention of these professionals, and to guide intact throughout life, but w ith aging the Bethesda, Md. 20205. them in interacting with information special­ taste and pleasantness of food overpower this This two-volume work was prepared by ists, in using the system themselves, and in regulatory mechanism. NINCDS to assist clinicians and researchers handling the specialized MEDLINE vocabulary.

November 27, 1979 The NIH Record Page3 BIKES Aller Lhe loop road is cornpleleJ next spring, Children's Books Available Free NIH plans to install a trail-marked bike lane From Consumer lnfor. Center (Con(inuc~cl from PJgc 1) for NIil employees. The lane will run from Old Georgetown Road to Rockville Pike, along employer in the county, and each day over It's the International Year of the Child, and Lincoln Drive, and will include a lane along 300 hicydist~ enter ;rnrl leave its grounds. the Consumer Information Center has some the Service Roads down South and Center free children's publications for this special One of the new breed of employees travels Drives. up to 22 miles per day to get to work. Most year. employees who ride their bikes to work, "We had to add five each year," says The Thing the Professor Forgot (52iG) Thomas Cook, chief, Maintenance and however, average 5 Lo (, miles per day round J. written in rhyme, takes children on a journey Landscaping Branch, about the number of trip. Their bikes may be p!aced at bike racks to learn about the four food groups. As the additional hike racks that his office ha, pro­ localed at 18 different NIH localions. All a professor says, "To have healthy bodies for "bikie" must provide is the lock and chain vided on campus during the last 3 years. work, sleep or play, eat many good foods for his or her own bike. He says that there seem to be more bike from fuur group:;. every day." One of the two-wheel enthusiasts is Dr. riders among the scientific community at Smokey Bear'.<; Story ol tne forest (W4G, Fredrickson, who each day, weather permit­ NII I than among the administrative and sup­ USDA) involves children in keeping tnc forests safo. Smokey tells how to go about ting, rides his bike from his home to his port areas. There arc over 100 bikics who putting out matches and campfires. office in Bldg. 1. "Besides em.:our;,ging our work at Bldg. 10 and over 80 who use the NI 11 employees to conserve energy, I can't racks at Rlrlgs_ 1fi and 17. Other children's booklets include: Dealing think of a more appropriate organization to Currently there are no requirements to with t,l-1e Angry Child (64'.iG, NIMI I). Children take the lead in supporting a form of trans­ register hicydt>s with Pith Pr the parking office and Television (647G), Helping Children portation that provides a health benefit," he or with lhe police at NIH. Make Career Plans (521Gi, Footsteps: A Parenting Guide ((,48G), and A Parent's Guide­ said at the \IIH biking program meeting. After the Nov. 7 mf>eting, 'JS employees to Childhood Immunization (522G). Presently, Montgomery County plans call signed up to organize an NIH Bicycle Com­ For a copy of any of the abuvc publica­ for the construction of access areas to NIH mu lers Association. The club's first organiza­ tion~, 5e11d a postcard with your name and from the east side of Cedar Lane and Rock­ tional meeting will be in the Billings Audi­ address to Consumer Information Center, ville Pike and on the south side from Battery torium at the National Library of Medicine, Pueblo, Colo. 81009. Lane to NIH by next sprine- on hiday, Dec. 7, from 12 to 1 :30 p.m. If you Cu rb and ramp construction is already need arlditional information, rail Dr. Harold taking place at all major crossroads at NIH. A. Wooster, 496-444-r. Louise M. Nett, Expert In Respiratory Disease Care, Proposed bikeways Joins NHLBI Council Louise M. Nett, respiratory care coordiriator Locations of existing at the University of Colorado Medical Center bike racks and in Denver, has been appointed to the * their capacity National Heart, Lung, and Blood Advisory Council. In addition to her coordinator duties in the Pulmonary Division of the Medical Center, Ms_ Nett also serves as a clinical associate professor of nursing in the University's School of :---Jur~ing. She has produced and directed four edu­ cational films, co-authored four books, written 35 scientific artidcs, and directed many courses and conferences on respiratory dis­ e<1,e c;are. She has also served on the faculties of national meetings and symposia on respira­ tory diseases, and has presented more than 150 programs throughout Colorado spon­ sored by the Statf' Regional Medical Program and the American Lung Association.

'Obesity in America' Available From FIC Publications Office

Obesity in America, a hook slemming from " t1 a conference on obesity, has just been pub­ ll * II lished by the Fogarty International Center. '' The book was edited by Dr. George A. Bray, former HEW coordindor of nutrition Bike racks for 18 different NIH locations and the new proposed bikeway arc shown above. programs and chairman of the conference. It i ncludcs reports on various aspcrts of obe~ity, Class on Media Relations Offered by USDA and fcatu res an overview containing recent statistics-by sex, age, and race-on the A class on Media Relations-which Allan TV, newspapers, and magazines. prevalence of overweight, guidelines for body Shapiro, associate producer of WJLA-TV, will Classes will meet every Thursday from 6 to weight, mortality in relation to deviation from teach-is being offered by the USDA Gradu­ 9 p.m. at the Department of Agriculture, average weight, and median caloric intake ate School. Washington, D.C. The cost of tuition is $60 values for persons aged 1 to 74. Beginning Jan. 10, participants will learn for the 10-week course. Interested health professionals can obtain a how to make media contacts, write press For further information, call 447-4419. copy of Obesity in America from the Fogarty releases, and get maximum benefit from radio, Publications Office, Bldg. 1GA, Rm. 205.

Page 4 The NIH Record November 27, 1979 Meeting on Microcomputers in Patient Care Hospital Epidemiologist Brings Together Developers and Users Named at the CC The use of microcomputers in medical considered three areas of usage for micro­ instruments, a development which has computers in medicine: use in medical history become feasible within the last decade, was taking, physical examination, laboratory test­ the subject of a recent°NIH consensus ing, and special procedures; use in diagnosis development conterence. and decision making; and use in treatment The meeting, which was sponsored by the and monitoring. Biomedical Engineering and Instrumentation They concluded that there is a role for Branch, Division of Research Services, was microcomputers in the physician's office. In held to bring together both users and devel­ some cases, they said, it would be helpful for opers of the new technology during its the physician to have the results of ce rtain formative stages. It provided a forum at tests before examining a patient, and micro­ which the physicians who use microcomputer­ computers could be used to gather this based instruments could convey their needs information quickly and accurately. to the researchers who develop them. They believe the goal of microcomputer Much attention has focused on microcom­ usage should be to "exceed physician capa­ puters recently. Manufacturing advances have bility, not just emulate it," especially as it enabled engineers to design computers so applies to decision making. Computerization Dr. Henderson and his staff will be in charge of tiny they can fit inside medical devices or is not appropriate for many medical decisions. the hospital's infection prevention program. even be implanted in patients. The relative The panelists called for the drafting of Dr. David K. Henderson is the new epi­ inexpensive cost and miniaturization of standards for microprocessor-based medical demiologist at the Cl inical Center. He is computers has already led to the develop­ instruments. They stressed that the standards certified in internal medicine and infectious ment of many new medical technologies. should be developed by medical and engi­ diseases and will direct the Infection Control Among the most interesting developments neering professional societies, and should not Program. are those incorporating microcomputers into inhibit innovation. The main objective of this program is to familiar medical devices. Microcomputer­ The participants at the meeting agreed that, prevent the occurrence of hospital-acquired based intensive care monitors, for example, despite impressive advances in microcom­ infections and to prevent transmission of might soon be capable of making medical puter technology, a number of problems still infection from patients to patient care staff or judgments about patients and, where time is exist. An example is the design of miniatur­ visitors. critical, autonomously modifying patients' ized sensors that could be implanted in Dr. Henderson, with the help of two treatment in response to their needs. patients to detect biological changes. At nurses, Joan Laniak and Ramona Myers, will Panelists at The Use of Microprocessor­ present, many such sensors can operate in assist nursing staff and other clinical depart­ Based " Intelligent" Machi nes in Patient Care the body for only a few days. ments on infection prevention measures.

Tom Coleman, Medical Communications Expert, Dr. Hoel Leads Group Joins NIAID On A-Bomb Study Tom Coleman, an expert in the medical communications field, recently joined the A work group of several U.S. scientists, led National Institute of Allergy and Infectious by Dr. David G. Hoel, is participating in an Diseases. on-site study of the long-term health effects Assigned to the Office of Research Report­ on survivors of the atomic explosions at ing and Public Response, Mr. Coleman will Hiroshima and Nagasaki, Japan. increase the flow of information to profes­ Dr. Hoel, chief of the Biometry Branch, sional groups and the general public and make National Institute of Environmental Health minority students aware of career opportu­ Sciences, was invited to participate by the nities in medical research. Initially, he will National Cancer Institute and the National concentrate on increasing NIAID's use of Academy of Sciences, which are conducting television, films, and satellite communications the study in collaboration with the U.S. for professional and patient education. Department of Energy and Japan. Mr. Coleman's extensive experience as a This project will use data gathered since health administrator and communicator began 1950 on a cooperative basis by U.S. and in 1951, when he joined the University of Japanese scientists about survivors of the Nebraska Medical Center. There he produced atomic bomb explosions, and will analyze some of the earliest television shows for how the epidemiological data on carcino­ educating the public about medicine and genicity compares with data from animal health. In the course of his career, Mr, Coleman has experiments. The work will be done in later, while assistant to the vice chancellor written more than 100 television and film scripts Hiroshima and Nagasaki, centered at the of the University of Pittsburgh Medical Center and many radio shows on medical and scientific Radiation Effects Research Foundation in from 1955 to 1957, Mr. Coleman served as subjects. Hiroshima. public affairs representative and trouble Because Dr. Hoel is an expert statistician shooter for Dr. Jonas Salk and his staff during As executive director of the National Asso­ in experimental design, epidemiology, the development and licensing of the polio ciation of Hearing and Speech Agencies, extrapolation of research results, and human vaccine. 1966-76, he developed an accreditation risk assessment, he was selected to head the In 1958, while assistant director of the program for local agencies and a certification multidisciplinary delegation which will con­ Association of American Medical Colleges, program for agency administrators. duct the study over a 9-month period. Mr. Coleman established a Teaching Hospital For the past 3 years, Mr. Coleman has Dr. Hoel received the Mortimer Spiegelman Section, and in 1962 he conducted a nation­ been a free lance writer and consultant to Gold Medal Award from the American Public wide study of medical communications for various health-related agencies, including Health Association in 1977; also, that same the PHS Neurological and Sensory Disease the NINCDS Science Information Program year, he was the recipient of the NIH service program. Advisory Committee. Director's Award.

November 27, 1979 The NIH Record Pages Philip Sapir Joins Staff of NICHD Rural Community Programs To Develop Plans As Special Assistant to Director For High Blood Pressure Control

Philip Sapir has joined the staff of the Model rural community programs to con­ National Institute of Child Health and Human trol high blood pressure will be developed Development as special assistant to the under three grants, totaling $2.8 million, Director of NICHD for Behavioral and Social awarded by the National Heart, Lung, and Sciences, advising on the full range of Blood Institute. The programs will be con­ Institute activities. ducted in areas with higher-than-average He will also oversee the activities of the prevalence of the disease. Human Learning and Behavior Branch. Each program, to be funded over 5 years, Mr. Sapir has held several positions within will be a community-wide effort, enlisting the Public Health Service, principally at the public and private resources for patient National Institute of Mental Health. He also education, disease detection, treatment, and has been with the National Research Council/ follow-up, in order to reach every person National Academy of Sciences; the Albert with high blood pressure. Ei nstein College of Medicine; and, most "The lnstitute's decision to develop these recently, the William T. Grant Foundation, model programs is based on information where he served from 1969 to 1978, starting which shows that communities with an above as associate director and ending as president. average percentage of citizens with high As assistant dean for faculty affairs at the blood pressure---more than 20 percent of the Albert Einstein College of Medicine, 1967 to adults in the pilot communities-often lack 1969, he had a variety of administrative In his most recent post at the Grant Foundation, Mr. Sapir developed and directed a broad adequate programs for managing and con­ responsibilities, including faculty organization trolling the disease," said Dr. Robert Levy, and committee structure, allocation of re­ program of support in areas relevant to child health. NHLBI Director. search resources, and supervision and revision An estimated 18 percent of American adults of procedures for research grant applications. managed extramural support in mental health Ke also was professor of community research, with a major emphasis on programs between ages 18 and 74 have high blood pressure. medicine. in the behavioral and social sciences. At NIMH, where he worked from 1949 until Mr. Sapir graduated from Yale University The three grantees are: Fort Valley State 1967, Mr. Sapir worked in the research grant and attended the New School for Social College in Georgia, the University of North program, serving for 12 years as chief of the Research and the Washington School of Carolina School of Public Health, and the Research Grants and Fellowships Branch. He Psychiatry. University of Kentucky College of Medicine.

Communications. Sponsor: Dr. A. Donald VISITING SCIENTIST PROGRAM PARTICIPANTS Merritt, NLM, Bg. 38, Rm. M137. 10/10-Dr. S. Roy Caplan, lsrael/U.S. Laboratory of Nutrition and Endocrinology, 11/4-Dr. Asher Frensdorff, Israel, laboratory of Theoretical Biology. Sponsor: Sponsor: Mr. Michael Lin, NlAMDD, Bg. 6, Laboratory of Viral Carcinogenesis. Sponsor: Dr. Mones Berman, NCI, Bg. 10, Rm. 4858. Rm. B1-22. Dr. Jeffrey Schlom, NCI, Bg. 37, Rm. 1819. 10/16- Dr. Carmelo Bruni, Italy, Laboratory 10/22-Dr. Benjamin Rivnay, Israel, Arthritis 11/4-Dr. Mathew M. Mathai, India, of Biochemical Pharmacology. Sponsor: Dr. and Rheumatism Branch. Sponsor: Dr. Henry Rehabilitation Medicine Dept. Sponsor: Dr. Matthew Rechler, NIAMDD, Bg. 4, Rm. 81-14. Metzger, NIAMDD, Bg. 10, Rm. 9N206. Lynn Gerber, CC, Bg. 10, Rm. 5D37. 10/16-Dr. David Messer, Luxembourg, 10/25-Dr. Corrado Garbi, Italy, Laboratory 11/4-Dr. Pierluigi Onali, Italy, Laboratory Social and Behavioral Sciences Branch. of Molecular Biology. Sponsor: Dr. Seymour of Preclinical Pharmacology. Sponsor: Dr. Sponsor: Dr. Leon Yarrow, NICHD, Bg. 31, H. Wollman, NCI, Bg. 37, Rm. 1 E16. Erminia Costa, NIMH, St. Elizabeths Hospital. Rm. 82815. 10/26-Dr. Jacob Wilf, Israel, Laboratory of 11/4-Dr. Toshiyuki Yoneda, Japan, 10/16-Dr. Lesley Messer, Luxembourg, Bioorganic Chemistry. Sponsor: Dr. Allen Laboratory of Developmental Biology and Laboratory of Molecular Genetics. Sponsor: Minton, NIAMDD, Bg. 4, Rm. B1-06. Anomalies. Sponsor: Dr. Robert Pratt, NIDR, Dr. Judith G. Levin, NICHD, Bg. 10, Rm. 8D52. 10/29- Dr. Katie R. Daruwalla, India, Bg. 30, Rm. 405. 10/16-Dr. Susy Marie Scholl, Luxembourg, Laboratory of Biochemical Genetics. Sponsor: 11 /5-Dr. Cleanthis-Demetre Froussios, Laboratory of Viral Carcinogenesis. Sponsor: Dr. Allen Minton, NIAMDD, Bg. 4, Rm. B1-06. Greece, Laboratory of Chemical Physics. Dr. Paul Levine, NCI, Landow Bg., Rm. C818. 10/30-Dr. Ding-Shinn Chen, Taiwan, Sponsor: Dr. Herman Ziffer, NIAMDD, Bg. 2, 10/17-Dr. Leon Kuczynski, Canada, Laboratory of Infectious Diseases. Sponsor: Rm. B1-06. Laboratory of Development Psychology. Dr. Robert Purcell, NIAID, Bg. 7, Rm. 202. 11/5- Dr. Peter R. Gardiner, United Sponsor: Dr. Marian Yarrow, NlMH, Bg. 15K. 10/31-Dr. David Wray, Scotland, Kingdom, Laboratory of Parasitic Diseases. 10/17-Dr. Satchithananda Pai, India, Laboratory of Oral Medicine. Sponsor: Dr. Sponsor: Dr. Dennis M. Dwyer, NIAID, Bg. 5, Laboratory of Pulmonary Function and Abner Notkins, NIDR, Bg. 30, Rm. 121. Rm. 114. Toxicology. Sponsor: Dr. Vernon Steele, 11/1- Dr. Fang-Ting Chiu, Taiwan, 11/6- Dr. Sevilla D. Detera, Philippines, NIEHS, Research Triangle Park, N.C. laboratory of Biochemistry and Metabolism. Laboratory of Biochemistry. Sponsor: Dr. 10/17-Dr. Isabelle Seif, France, Laboratory Sponsor: Dr. William Jakoby, NlAMDD, Bg. Samuel Wilson, NCI, Bg. 37, Rm. 4D23. of Molecular Virology. Sponsor: Dr. Robert 10, Rm. 9N109. 11/6-Dr. Josiane Wantyghem, France, Manaker, NCI, Bg. 41 , Rm. 200. 11/1-Dr. Gisela Degen, Germany, Laboratory of Immunology. Sponsor: Dr. 10/17-Dr. Peter Zuurendonk, Netherlands, l aboratory of Environmental Toxicology. Myron Waxdal, NIAID, Bg. 10, Rm. 11 N260. Laboratory of Metabolism. Sponsor. Dr. Sponsor: Dr. John Mclachlan, NIEHS, 11/7- Dr. Mariam K. I. George, India, Richard Vech, NIMA, Flow Lab. Research Triangle Park, N.C. Laboratory of Chemical Pharmacology. 10/21-Dr. Richard Clayton, United 11/1-Dr. Andrea Pavirani, Italy, Laboratory Sponsor: Dr. Gopal Krishna, NHLBI, Bg. 10, Kingdom, Endocrinology and Reproduction of Immunology. Sponsor: Dr. Rose Mage, Rm. 8N107. Research Branch, Sponsor: Dr. Kevin Catt, NIAID, Bg. 10, Rm. 11D10. 11/9-Dr. Shiroh Ida, Japan, Laboratory of NICHD, Bg. 10, Rm. 13N232. 11/1-Dr. Satoru Shimizu, Japan, laboratory Oral Medicine. Sponsor: Dr. Abner Notkins, 10/21- Dr. Eliezer Kedar, Israel, Laboratory of Chemical Biology. Sponsor: Dr. Jurrien NIDR, Bg. 30, Rm. 121. of lmmunodiagnosis, Sponsor: Dr. Ronald Dean, NlAMDD, Bg. 10, Rm. 9N321. 11/13-Dr. Kyozo Tsukamoto, Japan, Herberman, NCI, Bg. 10, Rm. 8B1 1. 11/4-Dr. Goran Falkenberg, Sweden, Laboratory of Viral Carcinogenesis. Sponsor: 10/22-Dr. Shay-Whey Koh, Taiwan, Lister Hill National Center for Biomedical Dr. Charles Boone, NCI, Bg. 37, Rm. 1C09.

Paga 6 The NIH Record November 27, 1979 NIH Plays Host to AAMC Public Relations Group Howard Morgan Named NIH played host to the Group on Public Relations To Sports Hall of Fame of the Association of American Medical Col­ Howard Morgan of the Office of Grants and leges recently with a Contracts, NICHD, was recently inducted into special half-day orienta­ the 1979 Athletic Hall ~f Fame of his alma tion in Wilson Hall. mater, Morgan State College in Baltimore. Representatives from He was honored for his athletic perform­ nearly 70 grantee insti­ ance during his college years, 1950-54. Mr. tutions attended. Morgan was o n the first freshman track team Storm Whaley, NIH for Morgan State to Win the Freshman Mile Associate Director for Relay Championship of America. The main Communications, wel­ event in which he competed was the open comed the visitors, and 440. Occasionally, he ran the half mile and NIH Director Dr. Donald the 220. S. Fredrickson briefly Mr. Morgan's participation in sports goes commented on the back to high school and includes football, stewardship of the tax- The MMC group attends a.n orientation meeting in Wilson Ha.II. basketball, boxing, and track. His achieve- payers' money for medi­ cal research, including the current reviews of Freedom of Information Act, ·investigative NIH research programs, the need for grantee audits of grantee institutions, and the early institutions to acknowledge Federal support warning system for announcing the awarding in press announcements, and the NIH 1981 of grants. budget outlook. Another panel alerted the visitors to NIH Several panels met. One discussed issues information services such as consensus devel­ which may affect grantee public relations, opment conferences, two-way press referrals, including recent court cases relating to the and local tie-ins to NIH promotional projects.

Dopamine May Play Role in Movement Problems of Aged; Drug Therapy Can Help, Research Suggests

Research on rats suggests that age-related continuous performance, and that they fail to changes in the central nervous system may be adjust their movements to compensate for responsible for many of the disturbances in their errors. At NIA's Gerontology Research movement that are seen with advanced age Center, investigators have noted that ability to and that this impairment can be reversed by perform complicated tasks declines more drug therapy. quickly with age than the ability to perform National Institute on Aging grantee Dr. John simple tasks that don't call for coordination, F. Marshall, department of psychobiology, like pushing and pulling a stationary object. University of California, Irvine, has found that Historically, such changes have been thought when compared with younger adult rats, aged to relate to decreased muscle strength or the animals move their limbs less vigorously accumulation of fat with age. during prolonged exercise. Such movement Similarly, numerous investigations in both Mr. Morgan breaks the tape during one of the dysfunctions are strikingly similar to those animals and humans have indicated age­ outstanding runs that led to his nomination into seen in young adult animals that have sus­ related changes in neurotransmission at brain the Sports Hall of Fa.me. tained injury to dopamine-containing dopaminergic synapses. ments throughout the years earned him such neurons in the brain. It has long been known that the dopamine­ honors as All-New York State, All-American, Dr. Marshall's findings, reported in the Oct. containing neurons of the brain play a critical and All-Air Force. 26 issue of Science, include evidence that the role in movement. Parkinson's disease, for His athletic ability carried over into the impaired function of the aged rats can be example, is characterized by rhythmical area of coaching. Recently, for 3 years he reversed by administration of L-dopa (the muscular tremors, rigidity of movement, and coached a girls' track team in Baltimore. The biosynthetic precursor of dopamine) or apo­ similar disturbances which are clearly attribu­ team started as a playground group, and morphine (a dopamine receptor stimulant). table to a loss of dopamine-containing under Mr. Morgan's coaching went on to win Research on aging has shown that elderly neurons. Dr. Marshall's research provides the the South Atlantic AAU Track Championship persons generally require more time to first clue that dopamine might play a role in and placed second in the Women's AAU prepare for and carry out movements, that the movement problems of healthy aged Championship in Cross Country. they pace themselves poorly in tasks requiring populations. Mr. Morgan, formerly an NICHD micro­ biologist, is now a policy analyst. He runs several miles each day, participates each year FTC Updates Pamphlet on Mail Order Rights in the NIH Institute Challenge Relay, and bowls regularly. Your rights when you order by mail are merchandise will be mailed, it must be spelled out in an updated pamphlet issued shipped to you no later than 30 days after Jean-Philippe Collard Featured by the Federal Trade Commission. they get an order. If you don't receive the In FAES Concert Dec. 2 If the ad says, "within 10 days," that's article shortly after that 30-day period, you Jean-Philippe Collard, a young French when the company must send it, and if the can cancel your order and get your pianist, will be featured in a concert to be company cannot send the merchandise money back. held. on Sunday, Dec. 2, at 4 p.m. in the when they say they will, they must give you For a free copy of Shopping by Mail, send Masur Auditorium. the option of cancelling the order and getting a postcard with your name and address to This is the third FAES concert in the 1979-80 a full refund. the Consumer Information Center, Dept. Chamber of Music Series. Admission is by If the seller does not say when the 690G, Pueblo, Colo. 81009. ticket only.

November 27, 1979 The NIH Record Page 7 SYMPOSIUM (Continued from Page 1) papio baboon. This herpesvirus appears to be associated with a lymphoma in the baboons similar in some ways to Burkitt's lymphoma, a type of cancer found in children in Africa. Burkitt's lymphoma is li nked to the Epstein­ Barr virus, an infectious and horizontally trans­ mitted herpesvirus that is endemic in the human population. The baboon lymphoma can affect the spleen, lymph nodes, liver, and lungs of the animals. Ten abstracts from Soviet bloc countries on bovine leukosis, including studies of disease incidence in cattle herds and attempts at vaccine development, were delivered. Soviet scientists reported that cattle of different breeds demonstrated varying susceptibility to leukemia and lymphoma. Despite concern about ,eduction of cattle herds due to leukemia or lymphoma, Soviet NIH fire officials and engineering workers inspect the damage done to a recently installed gas line scientists could find no evidence of increased when it was accidently struck by a backhoe at around 11 a.m. on Wednesday, Nov. 14. The escaping risk for these cancers among humans living gas caused the evacuation of Bldg. 7 a11d the A-wing of Bldg. 10. Officials say that the damage was in a five-district rural area outside of Moscow repaired, that there were no injuries, and after a 40-minute interruption employees returned to work. where bovine leukosis is relatively common. After the Pitsunda symposium, interviews with Soviet scientists in Moscow reflected NIEHS Scientists Develop Improved Technique broad Soviet interest in other areas of re­ search. The Institutes visited during 2 days of To Identify, Measure Environmental Toxins interviews have participated in joint American­ A screening procedure to identify and pieces of equipment needed are a centrifuge Soviet cooperation in cancer research. Prof. measure levels of one of the most toxic and a gamma counter, which are available for Viktor M. Zhdanov, Director of the D.I. lvan­ groups of environmental contaminants, other radioimmunoassays at many hospitals. ovsky Institute of Virology, described studies chlorinated dibenzo-p-dioxins (CDBD's), has TCDD has no chemically reactive functional of RNA tumor viruses of primates and cattle, been developed by scientists at the National groups. In developing the assay, NIEHS human herpes simplex viruses, and the Institute of Environmental Health Sciences. scientists synthesized a TCDD derivative that "swine flu" virus. The double-antibody radioimmunoassay retained most of the TCDD structural features procedure is relatively inexpensive, and can and added a reactive site. The derivative was be used with equipment already available in coupled to an immunogenic protein carrier hospitals. so that test animals would respond to it by The CDBD group of contaminants includes producing antibodies. TCDD (tetrachlorodibenzo-p-dioxin), which In the assay procedure, these animal­ is possibly the most toxic man-made chemical generated antibodies are combined with a known. TCDD was involved in the environ­ second compound similar to TCDD which is mental disaster at Seveso, Italy, in which a labeled with a radioactive isotope. residential neighborhood had to be evacu­ If no TCDD is present, all of the labeled ated. material is bound by the antibody. If TCDD is Previously, identification and monitoring of present, it will compete with the labeled CDBD's had to be done through high resolu­ derivatives for binding sites on the antibody, tion mass spectrometry, a procedure which and less of the labeled material will be identifies a substance by sorting a stream of bound. TCDD is detected and measured by charged particles (ions) by their mass. the decreased presence of labeled derivatives This technique requires expensive equip­ bound to antibodies. ment and highly trained staff, which in turn The radioimmunoassay procedure was limits the amount of identification and moni­ described in the October issue of Toxicology toring that can be done. Until now, there has and Applied Pharmacology. Authors of the Professor Zhdanov conducts his research at a been no way to confirm the spectrometric article were Ors. Phillip Albro, Michael Luster, hospital for patients with viral infections. Nearly 40 results. Kun Chae, and Su nil Chaudhary; George percent of the research al the Institute of Virology is on molecular problems such as the structure The new radioimmunoassay procedure can Clark; Lela Lawson; and Jean Corbett, all of and replication of RNA viruses. be prepared in kit form, with step-by-step the Laboratory of Environmental Chemistry, instructions for hospital technicians. The only and Dr. James McKinney, laboratory chief. Prof. L M. Shabad, department for carcinogenesis research, Oncologic Scientific National Institute on Aging Has Several New Publications Center, USSR Academy of Medical Science, described his studies of the polycyclic aro­ The National Institute on Aging has the marizes presentations given at the State of matic hydrocarbons, especially benzo-(a)­ following new publications now available the Art Seminar on Aging Research in 1977. pyrene, in diverse environmental settings. for distribution: Does Intelligence Decline with Age? NIH Studies of parenteral nutrition before and Recent Developments in Clinical and Re­ Pub. No. 79-1859, and Cells and Aging, after surgery in patients with localized cancers search Geriatric Medicine: The NIA Role, NIH Pub. No. 79-1860, also may be obtained. of the esophagus, throat, and stomach were NIH Pub. No. 79-1990, explains the develop­ To order single copies, include the number, described by Dr. A. V. Surrghan, chief of the ment of geriatric medical care of the elderly your name and address, and mail to: NIA, Laboratory of Parenteral Diet at the Center. by incorporating geriatrics into provider do Expand Associates, 8630 Fenton St., Stomach cancer is the most common form of training. Suite 508, Silver Spring, Md. 20910 or call the disease in adults in the Soviet Union, SCIENCE WRITER SEMINAR SERIES sum- 496-1752. (Continued on Page 9)

Page 8 The NIH Record November 27, 1979 Hamadryas baboons sun themselves in a new breeding enclosure. Another group of baboons is being maintained in a nearby forest, where they An animal holding pen houses research primates at the Institute of Experimental Pathology and Therapy have bred successfully for several generations. in Sukhumi. Founded in 1927, the Institute conducts studies on leukemia and lymphoma, the nervous system, acclimatization, and other aspects of primate research today.

(Continued from Page 8) Across Moscow at the P. A. Hertsen Sci­ N. P. Kuleshov described mutagenicity evalu­ entific Research Institute of Oncology, which ation of new drugs, chemicals in foods, and particularly in the northern parts of the specializes in radiotherapy and surgical treat­ industrial compounds, using tests in fruit country. ment for cancer, its director Prof. Boris E. flies, cells from mice, and microorganisms. Drug Development Lengthy in Both Countries Peterson described the Soviet medical care Dr. S. I. Kozlova discussed a medical referral Prof. Maria N. Preobrazhenskaya, chief of system and the organization of cancer care. service that provides genetics counseling to the Laboratory of Chemical Synthesis at the He said that medical examinations, including prospective parents. The service includes Center, described work in her laboratory on tests for cancer, are compulsory for all people medical tests such as amniocentesis, cyto­ the synthesis of new antimetabolites that may over 40. genetic analysis, and biochemical tests to be screened for anticancer activity in pre­ help predict occurrence of hereditary diseases clinical test systems. If found to be more and other possible abnormalities. Finally, Dr. active than existing drugs, a newly synthesized K. N. Grinberg described cell culture studies analog is formulated in amounts large enough to analyze the processing of genetic informa­ for clinical testing for toxicity and efficacy. tion in cells. The USSR drug development process, she Talks with Soviet scientists reflected a keen explained, is similar to the U.S. system for interest in research results from the West, development of new anticancer drugs. In both appreciation of progress resulting from cur­ countries, the process usually requires many rent US-USSR cooperation, and recognition of years. cancer as one of the most basic problems in biology.

Environmental Health Group Directory Available A Directory of Federal lnteragency Groups Concerned with Environmental Health has recently been published by the Task Force on Environmental Cancer and Heart and Lung Diseases. Monthly Calendar Published ln addition to the directory, the Task Force publishes a monthly calendar which lists events that pertain to environmental cancer Professor Peterson discussed cancer treatment and and heart and lung diseases. the training of oncologists at a 300-bed research A copy of the directory and the latest hospital. The Scientific Research Institute of edition of the calendar may be obtained from Oncology also coordinates a network of oncology Patricia R. Emerson, GEOMET, Inc., 15 Fair­ departments in Moscow and other parts of the field Rd., Gaithersburg, Md. 20760. For USSR. further information, contact Ms. Emerson, (301) 948-0755. Professor Preobrazhenskaya discussed Soviet A visit to the Soviet Institute of Medical efforts to synthesize and test new cancer Genetics revealed active research efforts in treatment drugs. chemical mutagenesis in cultured cells. Dr.

November 27, 1979 The NIH Record Page9 3 Prominent Scientists New Catalog Cites Some 3600 Join NIEHS Council Human Genetic Mutant Three prominent scientists-one in the field of toxicology, one in developmental biology Cell Lines and teratology, and one in pharmacology and A new catalog, citing approximately 3600 cardiovascular physiology-have been ap­ human genetic mutant cell lines available to pointed to the National Advisory Environ­ investigators upon request from the Institute mental Health Sciences Council: Ors. John for Medical Research, Camden, N.J., has been Edward Casida, Jeanne M. Manson, and published by the National Institute of General Janice Lee Stickney. Medical Sciences, sponsor of the cell resource. Dr. Casida is professor of entomology and The sixth edition of The Human Genetic an insect toxicologist at the University of Mutant Cell Repistory lists a collection of cell California at Berkeley. He was honored as a cultures stored in liquid nitrogen, including Haight Travel Fellow in 1958 and 1959, a human fibroblast, lymphoblast, and amniotic Guggenheim Fellow in 1970 and 1971, and fluid cell cultures from patients with bio­ E. won an international research award for chemical genetic disorders and chromosome Jane Collins, who has been at NIH since 1964, has accepted the post of information officer for pesticide chemistry from the American aberrations. Chemical Society in 1970. the Northeastern Region, Science and Education Administration U.S. Department of Agriculture, That same year he was awarded a Medal at Lists Cells Relevant to Aging Beltsville. Prio; to coming to the National Cancer the Seventh International Congress on Plant Also included in the catalog is a listing of Institute as a technical publications writer, she Protection in Paris for his research excellence. cells relevant to aging, which are supported worked for 10 years at the Sloan-Kettering Institute Dr. Casida's research interests include pesti­ by the National Institute on Aging. for Cancer Research. In 1974, she became a special cide chemistry and comparative biochemistry. assistant for scientific information to the Director Copies of the catalog may be obtained from Dr. Manson, assistant professor in the of Public Information, OC/OD. Ms. Collins has the NIGMS Office of Research Reports, been involved with the Science Writers Seminars department of environmental health at the Westwood Bldg., Rm. 9A10, 496-7301, or the University of Cincinnati College of Medicine, since their inception. She coordinated these Institute for Medical Research, Copewood and seminars, in which NIH scientists explain ongoing was an NIH postdoctoral fellow from 1974 to Davis Streets, Camden, N.J. 08103. research to the media. 1976, working in the department of environ­ mental health at the University of Cincinnati College of Medicine. Her research interests Recombinant DNA Office Is Transferred to NIAID focus on developmental biology and teratol­ ogy (study of birth defects). Dr. Stickney, associate professor of pharma­ cology at Michigan State University, was assistant professor of pharmacology in the School of Medicine at the University of California, San Francisco, from 1972 to 1975. Her research interests include studies on the role of the sympathetic nervous system on cardiac arrhythmias and the general cardio­ vascul ar effects of narcotic analgesics and anti-arrhythmic drugs.

Overeaters Anonymous Meets Weekly Al Westwood and Bldg. 31 Overeaters Anonymous, sponsored by the Occupational Medical Service, meets every Wednesday at noon in the Westwood Bldg., Conf. Rm. 428. Weekly meetings are also held in Bldg. 31. Newcomers are welcome.

Facing a Staff of the Office of Recombinant DNA Activities include (seated I to r): Drs. Stanley Barban, Gartland, and Elizabeth Milewski. Standing (I to r): Becky Connors, Betty Butler, Jan Montoya, and Crisis? Patricia Stein.

The Office of Recombinant DNA Activities jectural hazards associated with recombinant was transferred from the National Institute of DNA research. General Medical Sciences to the National Under NIAID, the office will continue to be Oi.al responsible for a wide variety of efforts, in­ 496-3164 Institute of Allergy and Infectious Diseases on Sept. 26. It is anticipated that the transfer will cluding the review of all applications sub­ NIH mitted to NIH involving recombinant DNA facilitate the administration of recombinant Employee technology and the implementation of NIH DNA activities supported and monitored by Assistance policies and procedures for conducting NIH. Program recombinant DNA research. NIAID will assume authority for the office Formed in 1976, the Office of Recombinant Confidenool Response in addition to supporting an ongoing program DNA Activities includes a staff of seven, on risk assessment research to evaluate con- headed by Dr. William Gartland.

Page 10 The NIH Record November 27, 1979 Conference Proceedings Issued On Decline in Coronary Chinese Experts on Diseases of Elderly Start Heart Disease Mortality U.S. Tour at Gerontology Research Center Proceedings of the Conference on the Decline in Coronary Heart Disease Mortality, October 24-25, 1978 has been issued by the GERONTOLOGY National Heart, Lung, and Blood Institute. Although heart attacks are still the major RESEARCH CENTER cause of death and disability in the United States, the Nation has had a major decrease in coronary heart disease mortality during the past 15 years.

Changes Recorded The presentations and discussions recorded in these proceedings address coronary heart d isease: changes in occurrence, changes in care, changes in risk factors, and strategies for quantifying and studying coronary heart disease. The 399-page publication includes a 42-page appendix of statistics, figu res, and tables prepared by the National Center for Health Statistics. Single copies are available free of charge from the NKLB I Public Inquiries and Reports On its first U.S. stop, the Study Group on Diseases of the Elderly from the People's Republic of China Branch, Bldg. 31, Rm. 4A-21. Ask for DHEW pauses outside the NIA Gerontology Research Center. Members of the group and their hosts, front I to r, Pub. No. (NIH) 79-1610. are: Dr. Jiaxin Gao, Prof. Kewei Huang, Dr. Nathan W. Shock, Or. Jiadong Deng, Dr. Luo Yi, Prof. Xiaoda Zhou, Dr. Cunhou Gao, and Dr. Mingxun Tan. Rear I lo rare GRC staff: Dr. Bruce Baum, Dr. Edward G, lakatta, and Dr. Greulich. Dr. Yanbing Wang, deputy head of the group and deputy director, Peking Nursing Department Hospital, was unavailable when this photo was taken. Presents Awards A delegation of eight prominent People's roles of NIH intramural and extramural pro­ At Meeting Republic of China scientists from Peking and grams, and emphasized the postdoctoral Shanghai began a 3-week tour of the U.S. on training opportunities available at GRC. Oct. 10 with a stop at the National Institute The lnstitute's clinical director, Dr. Reubin on Aging Gerontology Research Center in Andres, discussed the purpose and scope of Baltimore. the Baltimore Longitudinal Study of Aging, Led by Dr. Jiadong Deng, vice president of the Chinese Academy of Sciences and a and other laboratory chiefs described their professor of blood d isease, the Study Group studies. on Diseases of the Elderly is seeking informa­ After touring GRC, the Chinese scientists tion on degenerative, cerebrovascular, cardio­ visited several Baltimore area hospitals before vascular, and oral diseases in the older continuing their schedule. This included a population. The group includes members with visit to NIH in Bethesda, where they met with expertise in neurology, stomatology, blood NIA Director Dr. Robert N. Butler and intra­ disease, and internal medicine. mural scientists of the National Institute of Ms. Ferguson Ms. Rugg At the GRC, Dr. Richard C. Greulich, NIA Neurological and Communicative Disorders During the Clinical Center Nursing Depart­ scientific director, outlined research programs and Stroke, the National Heart, Lung, and ment's Sixth Annual Program Meeting, depart­ under way at the center, described its histori­ Blood Institute, and the National Institute of mental awards were presented for the first cal development, explained the respective Mental Health. time on Oct. 9 in the Masur Auditorium. Vernice Ferguson, chief, Nursing Depart­ Postdoctoral Scientists Offered Impact of HEW Planning on NIH ment, was honored as the first member of Congressional Fellowships Subject of Next STEP Forum the newly created CC Assembly of Distin­ In Child Development guished Nurses. She was selected for her HEW Health Research Planning: Impact on contributions outside the Clinical Center. Congressional Science Fellowships in Child NIH Programs will be the subject .of a dis­ 'Nurse of the Year' Development, sponsored by the American cussion to be held Wednesday, Dec. 12, Association for the Advancement of Science from 2 to 4 p.m., in the Westwood Bldg., Juliana Rugg, clinical nurse with the and the Society for Research in Child Devel­ Conf. Rm. D. Mental Health Nursing Service, CC, was opment, are being offered to postdoctoral selected as the Nurse of the Year for the scientists or professionals in the social, behav­ Perpich leads Discussion department. She was recognized "for her ioral, and health-related sciences for 1 year on The discussion, which will be led by Dr. demonstration of exemplary practice and her a Congressional staff. Joseph Perpich, NIH Associate Director for contri butions to patient care within a research Midcareer applicants are especially urged to Program Planning and Evaluation, is part of environment." apply. Fellows should be exceptionally com­ the Staff Training for Extramural Programs Also at the meeting, guest speakers Dr. petent in their field and strongly committed to forum series. Madeline Leininger, dean and professor of applying scientific knowledge to the solution Joseph Brackett, Division of Research nursing at the University of Utah, and Dr. of social problems. The stipend is $18,000 for Grants, will present background information Arthur Levine, Chief, Pediatric Oncology 1 year starting Sept. 1, 1980, with $1,500 on models of stability being developed to Branch, NCI. They spoke on the changes that available for relocation. help with decision making about allocations are influencing health care and the nursing For application information contact: Society of NIH resources. profession. Their remarks will be published for Research in Child Development, 815 15th For further information, call Bnan Kimes, in a nursing monograph late next year. Street, N.W., Washington, D.C. 20005. 496-7028, or Joan Porter, 496-7954.

November 27, 1979 The NIH Record Page 11 Public Meeting To Discuss Preliminary Evaluation Of Carcinogenicity Tests

A public meeting to discuss the p reliminary assessment of the results of a meeting of the International Program for the Evaluation of Short-Term Tests for Carcinogenicity will be held on Monday, Dec. 3, from 9:30 a.m. to 12:30 p.m., in the Masur Auditorium. The meeting is sponsored by the National Toxicology Program. Members of the Pro­ gram's coordinating committee will discuss conclusions reached at a meeting held Oct. 17-22 to evaluate test data obtained over the past 3 years, as well as conclusions during subsequent evaluation and summarization.

Attednance Limited Attendance by the public will be limited to space available. Anyone wishing to attend is requested to write to Ceci Ellington, National Institute of Environmental Health Sciences, P. 0. Box 12233, Research Triangle Park, N.C. Dr. Jesse Roth (r), chief of NIAMDD's Diabetes Branch, holds the $100,000 Lita Annenberg Hazen 27709. Further information about the meeting Award for outstanding achievement in clinical resear:h. He received the award Nov. 1 at the St. Regis can be obtained by calling Ms. Ellington, Hotel in New York. Presenting the award are Dr. Thomas Chalmers (I), President, Mount Sinai Medical Center, and Mrs. Lita Annenberg Hazen. (919) 541 -3492 (FTS 629-3492). Hilda Wexler Receives ACS Award Dr. Rall Will Discuss Toxicology Program Goals For Community Service During Toxics Conference

Hilda Wexler, a biologist in the Surgery The National Toxicology Program, its Branch of the National Cancer lnstitute's development and goals, will be discussed by Clinical Oncology Program, recently received Dr. David P. Rall at a luncheon on Dec. 10 the John F. Fenney Memorial Service Award during the Toxics Control Conference, for her outstanding work in community presented by Government Institutes Dec. health programs and for her personal involve­ 10-11 at the Shoreham Americana Hotel in ment with cancer patients and their famil ies. Washington, D.C. The award, sponsored by the D.C. Division Dr. Rall is Director of both the National of the American Cancer Society, is presented Toxicology Program, which coordinates annually to a volunteer worker who has made toxicology research and testing within HEW, exceptional contributions to the success of the Division's health education programs. and the National Institute of Environmental Health Sciences. "Hilda has been an incredible volunteer for almost 30 years and has shown great dedica­ Chemicals are being tested for their poten­ tion in taking our public health education tial to cause cancer, mutations, teratology programs right to the most needy people," (birth defects), immunologic or target organ said Sanford Milwit, executive director of the toxicities, and reproductive and develop­ ACS's local division. mental anomalies. Miss Wexler, who holds several American The first NTP annual plan, outlining the Cancer Society positions including division Program's goals, was recently presented to the vice president, accepted the award at a scientific community and the public. It is special dinner ceremony at the Fort McNair avai lable from: NTP Deputy Director, P.O. Officer's Club on Nov. 20. Box 12233, Research Triangle Park, N.C. Miss Wexler has a master's degree in 27709. biology from George Washington University Listed in the "Who's Who of American Women," For more information on the Toxics Control and has coauthored almost 30 scientific Miss Wexler has been with NCI for 20 years and Conference, call Marquerite Leichman, articles. has received three Superior Performance Awards. Government Institutes, (301) 656-1090.

Medicine for the Layman Series Schedules Last Two Lectures-Nov. 27, Dec. 4 On Tuesday, Nov. 27, Dr. Arthur Nienhuis, Auditorium. Dr. Robert Chanock, chief, Labo­ out in a few weeks and next month a pam­ N HLBI, will discuss Sickle Cell Anemia and ratory of Infectious Diseases, NlAID, will phlet on cancer treatment will be available. Thalassemia, as part of the Clinical Center's present a layman's lecture on Viruses and The information in these brod1ures is based Medicine for the Layman series. His lecture their impact on the world population. He will on the Medicine for the Layman lectures held will cover these two genetic disorders that also talk about respiratory and gastroin­ last year. For your free copy, stop by the CC affect red blood cells, and current research testinal diseases, and viral hepatitis. Office of Clinical Reports and Inquiries, Bldg. and new therapies. A series of pamphlets are now available on 10, Rm. 1A-05, or call 496-2563. The last lecture of the year will be held on the brain, lungs, heart attacks, and high blood Tuesday, Dec. 4, at 8 p.m., in the Masur pressure. A brochure on obesity will be *U.S. GOVERNMENT PRINTING OFFICE: l97ll--311-2O3/6

Page 12 The NIH Record November 27, 1979