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SUNDAY, JULY 3, 2016 (PAGE 4) BOLLYWOOD-BUZZ HEALTHLINES “I grew up admiring Nutan, Waheeda, Sridevi and Madhuri” A rare genetic disorder Bollywood actress Hrishitaa Bhatt, who was last seen playing Maya in 'Miss Tanakpur Haazir Ho' plays the role Dr. Swarkar Sharma human body. As DNA is inherited, these instructions are of a Bengali woman in Vivek Agnihotri's 'just released inherited from parents to children. Junooniyat'. Jaideep Pandey in conversation with the 34 Jammu and Kashmir State is mainly a hilly Sometimes, if an error occurs in a gene (mutation), that year old, who is more popularly known as Niharika Singh could be by chance, the biological instructions are affect- terrain, so majority of the population groups in Uttar Pradesh. ed or changed, resulting in a disease situation. And once Tell us about your role in 'Junooniyat'. exist in small geographic pockets through out this change appears, may be inherited to next generation Well, Junooniyat' is basically a love story and I am play- and in due course mutation and disease keeps accumulat- ing Mishti in the movie, who is a Bengali girl and has lost the state. With geographic isolation and most ing in the family. It may attain alarming proportions if her husband at a very early age. And when you will see me of the population groups practicing and unchecked as we had seen in Arai Village. So, it is very crit- and Yami on screen, you will feel as if we are sisters, but ical to identify families where such disorders exist. Though Mishti is Yami’s brother's wife. I am a catalyst in the movie performing marriages preferentially identification and characterization of such disorders is who plays the lead role in taking Yami and Pulkit's love- within particular subgroups, result in high complicated, it is relatively easy to find if a disorder is story forward. And although it is a guest appearance, I am Genetic or hereditary. The rule of the thumb is, if a disor- sure people will like and remember it. inbreeding in the state. der could not be diagnosed conventionally or the exact 'Junooniyat' is a kind of love-story that has cause is not known, might have a genetic component been put forward by Vivek Agnihotri in a com- Adding to it, majority of population of Jammu and Kashmir practice consanguinity (i.e. marriage with in the involved. Patients suffering from such disorders most of pletely different manner. And I can say that some- the times do not respond to conventional therapy or one like Vivek ji only can come up with such a family). Scientific evidences now confirm that high con- script. sanguinity cause high incidence of rare genet- Your experience working with Vivek Agni- ic disorders. In light of such population struc- hotri? ture in J&K, a high incidence of rare genetic I think he is a wonderful director and I always wanted disorders is expected in the state. Unfortu- to work with him. And when he told me about the role, I nately, due to lack of good clinical and diag- agreed to do it. It was an amazing experience working with nostic resources, many of these have not been him, will surely like to do more work with him in future. diagnosed or misdiagnosed. One co-actor you had the best chemistry with. Very recently, our team has successfully I think that is for my audience to tell me because frankly characterized one such disorder and identi- I really cannot be selective because I think as an actor the fied the genetic cause of it. The research work first key rule is to have a chemistry with your co-actor in has now been acclaimed by international sci- the movie, no matter what role you are playing, be of a love entific community and last week been pub- interest, or a daughter, or a wife. So, I think chemistry is lished in the renowned scientific journal, something that should be lucid on screen and bring out Nature Scientific Reports. This discovery has solved the mystery of decades old crippling a kind of bond that the two people share. I think the audi- skeletal disorder of Arai village of Poonch ence is the better judge when it comes to chemistry with Well I would say director as well as script because even District, Jammu and Kashmir, India. co-stars. if the script is great and the director is not good then the The team identified it as Progressive How was your experience working with Yami script can go wrong. So it really does matter that both Pseudorheumatoid Dysplasia (PPD). Other- and Pulkit. should be good at the time. The director could be a fresh- wise rare, due to lack of characterization and The experience of working with both of them has been er also, but at the same time it has to be a blend of both. proper management, the disorder has gained excellent. In-fact many people on the sets were surprised The Director is the captain of the ship and the script is the alarming proportions in the village. to see the bonding between me and Yami, because nor- ship itself. In many of such disorders, that are not mally we don't find such good chemistry between the two You will seen performing on "Mast Hawa" in lethal in early age, individuals remain normal female co-stars. 'Shorgul'. Would you agree that a political drama, at birth and have disease symptoms later in Any actress you grew up admiring. especially when it is based on UP and Bihar, is age that keep on intensifying with advance- I grew up admiring Nutan ji a lot, Then I was quite incomplete without an item number. ment of age, sometimes resulting in loss of young. And I remember that I loved watching Waheeda ji Somehow I don't know why but yes, in a cliched sense. life. These disorders as such appear rare how- (Waheeda Rehman I have been a dancer and loved watch- And moreover such stories do not have a lot of scope for ever, if unattended in due course may turn ing her since the age I can understand what's happening music and dance, especially if there is no element of a love out to be huge problem. Worldwide, Genet- in the film. story. So, to break the monotony and to add some Masala, ics has started to attain key position in healthcare servic- despite treatment, partial relief or symptoms do not van- To watch anybody dance or act looked so nice and beau- they put in an item number. es and rare disorders screening and Orphan drug devel- ish and reappear. tiful. I think I really looked up to these women beside there How would you rate Tigmanshu Dhulia as a opment is attaining importance as altogether these pose The main key component: more than one person is are lot more. Also Sridevi and Madhuri because I have director? huge health burdens. However, such practices are still affected in extended family (that involves, paternal and grown up watching them. I can say that I love Kajol, she Well I am nobody to rate him. I have always had respect lacking in India, especially Jammu and Kashmir. maternal grandparents, uncles, aunts, cousin etc). Such is wonderful. So for that matter, lot of actress, I would say. for his work from the day I met him. I think now he is Understanding the basics of inheritance is essential as disorders ask for special approach and I invite sharing I think Neetu Singh was also a different kind of an actress somebody. In-fact while we were shooting for 'Haasil' it helps to figure out the plausibility of a disorder as an such information at swarkar. sharma@ smvdu.ac.in or in her time and yes I think somewhere they have all (2003), he hardly spoke because he was so new and he inherited disease or genetic disease. For a brief overview, [email protected], to help you or the family in better inspired me. had just done some television, but he was brilliant as Deoxyribonucleic Acid (DNA) contains biological instruc- understanding. What is more important to you while signing a always. And I think he is going to be one of those who will tions (called the genes) for the various functions in the (The author is Co-ordinator, Human Genetics Research Group, School of Biotech- film. Script or the director? be making a mark in the Indian cinema. (TWF) nology Shri Mata Vaishno Devi University Katra.) SCIENCE & TECHNOLOGY Lifestyle and Fertility Issues Dr Richa Sharma & Dr Amit Basnotra It’s a common saying that we beget of what we do in Life ! Toxicants enter the body in one Same is happening in today’s time as too much of inter- ference with nature by human activities has resulted into or more of three ways: inhalation, compensation in form of deterioration of health- mental,physical,reproductive etc.Its high time to keep a ingestion, or absorption through check on all we do and respect our nature and keep our environment clean and healthy and bless coming genera- the skin. After entering the body, tions with a healthy and quality life and relieve them of all toxicants are distributed to various poisons and toxins mixed in air we breathe and water and other ingradients we consume.Lets Pledge to make Earth tissues and subject to metabolism A HEAVEN in this birth only. To enlighten our readers hereby we are sharing few and excretion.