Paranoid Personality Disorder
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Negative Symptoms in Schizophrenia
Reward Processing Mechanisms of Negative Symptoms in Schizophrenia Gregory P. Strauss, Ph.D. Assistant Professor Department of Psychology University of Georgia Disclosures ACKNOWLEDGMENTS & DISCLOSURES ▪ Receive royalties and consultation fees from ProPhase LLC in connection with commercial use of the BNSS and other professional activities; these fees are donated to the Brain and Behavior Research Foundation. ▪ Last 12 Months: Speaking/consultation with Minerva, Lundbeck, Acadia What are negative symptoms and why are they important? Domains of psychopathology in schizophrenia Negative Symptoms ▪ Negative symptoms - reductions in goal-directed activity, social behavior, pleasure, and the outward expression of emotion or speech Cognitive Positive ▪ Long considered a core feature of psychotic disorders1,2 Deficits Symptoms ▪ Distinct from other domains of psychopathology (e.g., psychosis, disorganization) 3 ▪ Associated with a range of poor clinical outcomes (e.g., Disorganized Affective disease liability, quality of life, subjective well-being, Symptoms Symptoms recovery) 4-7 1. Bleuler E. [Dementia praecox or the group of schizophrenias]. Vertex Sep-Oct 2010;21(93):394-400. 2. Kraepelin E. Dementia praecox and paraphrenia (R. M. Barclay, Trans.). New York, NY: Krieger. 1919. 3. Peralta V, Cuesta MJ. How many and which are the psychopathological dimensions in schizophrenia? Issues influencing their ascertainment. Schizophrenia research Apr 30 2001;49(3):269-285. 4. Fervaha G, Remington G. Validation of an abbreviated quality of life scale for schizophrenia. Eur Neuropsychopharmacol Sep 2013;23(9):1072-1077. 5. Piskulic D, Addington J, Cadenhead KS, et al. Negative symptoms in individuals at clinical high risk of psychosis. Psychiatry research Apr 30 2012;196(2-3):220-224. -
Autism Spectrum Disorders Among Adolescents and Adults and Comparison with Schizophrenia
The European Research Journal 2019;5(6):962-968 ORIGINAL ARTICLE Autism spectrum disorders among adolescents and adults and comparison with schizophrenia Aylin Küçük1 , Fulya Maner2 , Mehmet Emin Ceylan3 1Department of Psychiatry, Adana City Training and Research Hospital, Adana, Turkey 2Department of Child Development, Kırklareli University, Kırklareli, Turkey 3Deparment Of Psychology, Üsküdar Üniversty, İstanbul, Turkey DOI: 10.18621/eurj.441214 ABSTRACT Objectives: Autism Spectrum Disorders (ASD) may be commonly misdiagnosed as schizophrenia due to common symptoms and accompanying psychotic manifestations in both adolescence and adulthood. The purpose of this study is to examine and compare the autistic symptoms and positive and negative symptoms of schizophrenia in cases diagnosed as Autism Spectrum Disorder. Methods: Twenty-one patients between ages of 16-36 who have admitted to outpatient clinic have previously been diagnosed as autism spectrum disorders (autistic disorder, Asperger Syndrome, pervasive development disorder not otherwise specified) according to DSM-IV diagnosis criteria, have an IQ of 50 or above, have been included in the study. Control group have been composed of 21 patients between ages of 21-39 who have been diagnosed as schizophrenia according to DSM-IV diagnosis criteria and have an IQ of 50 or above. Psychiatric assessment has been made with Childhood Autism Rating Scale (CARS), Scale for the Assessment of Positive Symptoms (SAPS), Scale for the Assessment of Negative Symptoms (SANS), SCID-I and WAIS. Results: The negative symptoms of ASD are found to be higher than schizophrenia cases where as the positive symptoms of schizophrenia cases are found to be higher than ASD cases. Twenty percent (n = 4) of OSB cases do not meet autism symptoms while none of the schizophrenia cases meet autism symptoms. -
The Latent Structure of Negative Symptoms in Schizophrenia
Supplementary Online Content Strauss GP, Nuñez A, Ahmed AO, et al. The latent structure of negative symptoms in schizophrenia. JAMA Psychiatry. Published online September 12, 2018. doi:10.1001/ jamapsychiatry.2018.2475 eTable 1. Confirmatory Factor Analysis Models for the Scale for the Assessment of Negative Symptoms (SANS) eTable 2. Confirmatory Factor Analysis Models for the Brief Negative Symptom Scale (BNSS) eTable 3. Confirmatory Factor Analysis Models for the Clinical Assessment Interview for Negative Symptoms (CAINS) This supplementary material has been provided by the authors to give readers additional information about their work. © 2018 American Medical Association. All rights reserved. Downloaded From: https://jamanetwork.com/ on 10/02/2021 eTable 1. Confirmatory Factor Analysis Models for the Scale for the Assessment of Negative Symptoms (SANS) SANS Items and Domains Mean SD Range CFA Models UNI MAP/EXP Consensus Consensus HM 1st 2nd order order Anhedonia 15. Anhedonia 1.7 1.3 0-5 1 1 1 1 1 Asociality 14. Asociality 2.2 1.3 0-5 1 1 2 2 1 16. Decreased Sex. 2.7 1.7 0-5 1 1 2 2 1 Interest/Activity 17. Ability Feel 1.9 1.3 0-5 1 1 2 2 1 Intimacy/Closeness Avolition-Apathy 10. Grooming and 1.1 1.2 0-5 1 1 3 3 1 Hygiene 11. Current Role 3.6 1.6 0-5 1 1 3 3 1 Function - Level 12. Current Role 1.9 2.1 0-5 1 1 3 3 1 Function – Quality 13. Physical Anergia 2.4 1.4 0-5 1 1 3 3 1 Affective Flattening/Blunting 1. -
The Clinical Presentation of Psychotic Disorders Bob Boland MD Slide 1
The Clinical Presentation of Psychotic Disorders Bob Boland MD Slide 1 Psychotic Disorders Slide 2 As with all the disorders, it is preferable to pick Archetype one “archetypal” disorder for the category of • Schizophrenia disorder, understand it well, and then know the others as they compare. For the psychotic disorders, the diagnosis we will concentrate on will be Schizophrenia. Slide 3 A good way to organize discussions of Phenomenology phenomenology is by using the same structure • The mental status exam as the mental status examination. – Appearance –Mood – Thought – Cognition – Judgment and Insight Clinical Presentation of Psychotic Disorders. Slide 4 Motor disturbances include disorders of Appearance mobility, activity and volition. Catatonic – Motor disturbances • Catatonia stupor is a state in which patients are •Stereotypy • Mannerisms immobile, mute, yet conscious. They exhibit – Behavioral problems •Hygiene waxy flexibility, or assumption of bizarre • Social functioning – “Soft signs” postures as most dramatic example. Catatonic excitement is uncontrolled and aimless motor activity. It is important to differentiate from substance-induced movement disorders, such as extrapyramidal symptoms and tardive dyskinesia. Slide 5 Disorders of behavior may involve Appearance deterioration of social functioning-- social • Behavioral Problems • Social functioning withdrawal, self neglect, neglect of • Other – Ex. Neuro soft signs environment (deterioration of housing, etc.), or socially inappropriate behaviors (talking to themselves in -
Songs by Title
Karaoke Song Book Songs by Title Title Artist Title Artist #1 Nelly 18 And Life Skid Row #1 Crush Garbage 18 'til I Die Adams, Bryan #Dream Lennon, John 18 Yellow Roses Darin, Bobby (doo Wop) That Thing Parody 19 2000 Gorillaz (I Hate) Everything About You Three Days Grace 19 2000 Gorrilaz (I Would Do) Anything For Love Meatloaf 19 Somethin' Mark Wills (If You're Not In It For Love) I'm Outta Here Twain, Shania 19 Somethin' Wills, Mark (I'm Not Your) Steppin' Stone Monkees, The 19 SOMETHING WILLS,MARK (Now & Then) There's A Fool Such As I Presley, Elvis 192000 Gorillaz (Our Love) Don't Throw It All Away Andy Gibb 1969 Stegall, Keith (Sitting On The) Dock Of The Bay Redding, Otis 1979 Smashing Pumpkins (Theme From) The Monkees Monkees, The 1982 Randy Travis (you Drive Me) Crazy Britney Spears 1982 Travis, Randy (Your Love Has Lifted Me) Higher And Higher Coolidge, Rita 1985 BOWLING FOR SOUP 03 Bonnie & Clyde Jay Z & Beyonce 1985 Bowling For Soup 03 Bonnie & Clyde Jay Z & Beyonce Knowles 1985 BOWLING FOR SOUP '03 Bonnie & Clyde Jay Z & Beyonce Knowles 1985 Bowling For Soup 03 Bonnie And Clyde Jay Z & Beyonce 1999 Prince 1 2 3 Estefan, Gloria 1999 Prince & Revolution 1 Thing Amerie 1999 Wilkinsons, The 1, 2, 3, 4, Sumpin' New Coolio 19Th Nervous Breakdown Rolling Stones, The 1,2 STEP CIARA & M. ELLIOTT 2 Become 1 Jewel 10 Days Late Third Eye Blind 2 Become 1 Spice Girls 10 Min Sorry We've Stopped Taking Requests 2 Become 1 Spice Girls, The 10 Min The Karaoke Show Is Over 2 Become One SPICE GIRLS 10 Min Welcome To Karaoke Show 2 Faced Louise 10 Out Of 10 Louchie Lou 2 Find U Jewel 10 Rounds With Jose Cuervo Byrd, Tracy 2 For The Show Trooper 10 Seconds Down Sugar Ray 2 Legit 2 Quit Hammer, M.C. -
Running Head: AUTISM SPECTRUM DISORDER and SCHIZOPHRENIA 1
Running head: AUTISM SPECTRUM DISORDER AND SCHIZOPHRENIA 1 Autism Spectrum Disorder and Schizophrenia A Literature Review Presented to The Faculty of the Adler Graduate School ____________________ In Partial Fulfillment of the Requirement for The Degree of Master of Arts in Adlerian Counseling and Psychotherapy ____________________ By Björn Walter ____________________ Chair: Richard Close, DMin, LPCC, LMFT Reader: Meghan Williams, MA, LMFT ____________________ August, 2017 AUTISM SPECTRUM DISORDER AND SCHIZOPHRENIA 2 Abstract This literature review sets out to compare the similarities and the differences between autism spectrum disorder and schizophrenia. To understand the relationship between the two disorders, this project includes an examination of the historical timeline, an analysis of the diagnostic criteria, the impact and effectiveness of various treatments for autism spectrum disorder and schizophrenia. Emphasis is on Adlerian therapy, pharmacological treatment through antipsychotic medications, and the legal and ethical issues as a result of misdiagnosis. To achieve understanding around ethical and legal concerns regarding misdiagnosis, this project includes a hypothetical case study to demonstrate potential harm after the wrong treatment. The primary purpose of this paper is to increase awareness of the problematic situations that arise when the autism spectrum disorder and schizophrenia are misdiagnosed. Keywords: autism spectrum disorder, schizophrenia, Adlerian therapy, antipsychotic medication, DSM-5 AUTISM SPECTRUM DISORDER AND SCHIZOPHRENIA 3 Acknowledgements I would first like to thank my colleagues at the Autism Society of Minnesota. I would like to particularly extend my gratitude to Dr. Barbara Luskin. You inspired me to complete this project, and I will always be grateful for the support you gave me. I would also like to thank my family for always being there for me. -
Distinct Effects of Social Motivation on Face Evaluations in Adolescents
www.nature.com/scientificreports Corrected: Author Correction OPEN Distinct efects of social motivation on face evaluations in adolescents with and without autism Received: 5 October 2017 Lou Safra 1, Christina Ioannou1, Frédérique Amsellem2,3, Richard Delorme2,3 & Accepted: 21 June 2018 Coralie Chevallier1 Published online: 13 July 2018 Individual diferences in social motivation have an infuence on many behaviours in both clinical and non-clinical populations. As such, social motivation has been identifed as a biological trait that is particularly well-suited for dimensional approaches cutting across neuropsychological conditions. In the present paper, we tested whether social motivation had a similar impact in the general population and in a neuropsychological condition characterized by diminished social motivation: Autism Spectrum Disorders (ASD). More precisely, we evaluated the efect of social motivation on face evaluations in 20 adolescents with ASD and 20 matched controls using avatars parametrically varying in dominance and trustworthiness. In line with previous research, we found in the control group that participants with higher levels of social motivation relied more on perceived trustworthiness when producing likeability judgments. However, this pattern was not found in the ASD group. Social motivation thus appears to have a diferent efect in ASD and control populations, which raises questions about the relevance of subclinical or non-clinical populations to understand ASD. Compared to many other animals, humans stand out when it comes to the variety of social interactions they pursue and the importance of social activities in their ecological niche1. Te willingness to be included in social interactions and the propensity to preferentially attend to the social world is present early on in development and remains a driving force throughout the lifespan2–4. -
Running Head: SOLITUDE I Understanding the Potential Of
Running Head: i SOLITUDE Understanding the Potential of Solitude by Leslie Williams A thesis submitted in partial fulfillment of the requirements for the degree of Master of Counselling (MC) City University of Seattle Vancouver BC, Canada site 2017 APPROVED BY Christine Dennstedt, Ph.D., R.C.C., Thesis Supervisor Glen Grigg, Ph.D., R.C.C., Faculty Reader Division of Arts and Sciences SOLITUDE ii Abstract This thesis seeks to investigate the positive psychology of solitude. Solitude can be viewed as a kind of positive aloneness, a sought out and enjoyable experience that is not usually associated with negative emotions. For some, spending time alone is to be avoided at all costs; for others, time spent alone can be enjoyable and a necessity. Solitude is a volitional state and as such is intrinsically considered a beneficial sort of aloneness in contrast to loneliness (McGraw, 2010). Making a clear distinction between these two very different experiences is key to exploring how therapists may collaborate with clients to find a sense of a personal private space, and explore the positive possibilities of time spent alone. Be it through creativity, spirituality or being immersed in nature, solitude and the awareness it can facilitate, allows for greater connection and participation with personal meanings and truths, both internally and in relationship. SOLITUDE iii Table of Contents Abstract...............................................................................................................................ii Acknowledgements.............................................................................................................v -
Marking the 20Th Anniversary of the Fall of the Berlin Wall Responsible Leadership in a Globalized World
A publication of the Contributors include: President Barack Obama | James L. Jones Chuck Hagel | Horst Teltschik | Condoleezza Rice | Zbigniew Brzezinski [ Helmut Kohl | Colin Powell | Frederick Forsyth | Brent Scowcroft ] Freedom’s Challenge Marking the 20th Anniversary of the Fall of the Berlin Wall Responsible Leadership in a Globalized World The fall of the Berlin Wall on November 9, 1989, not only years, there have been differences in opinion on important led to the unifi cation of Germany, thus ending decades of issues, but the shared interests continue to predominate. division and immeasurable human suffering; it also ended It is important that, in the future, we do not forget what binds the division of Europe and changed the world. us together and that we defi ne our common interests and responsibilities. The deepening of personal relations between Today, twenty years after this event, we are in a position to young Germans and Americans in particular should be dear gauge which distance we have covered since. We are able to to our hearts. observe that in spite of continuing problems and justifi ed as well as unjustifi ed complaints, the unifi cation of Germany and For this reason the BMW Foundation accounts the Europe has been crowned with success. transatlantic relationship as a focus of its activity. The Transatlantic Forum for example is the “veteran“ of the It is being emphasized again and again, and rightly so, that it BMW Foundation’s Young Leaders Forums. The aim of was the people in the former GDR that started the peaceful these Young Leaders Forums is to establish a network, revolution. -
The Clinical Utility of Personality Profiles of High-Risk Offenders in Rehabilitation
The Clinical Utility of Personality Profiles of High-Risk Offenders in Rehabilitation by Morgan K. A. Sissons A thesis submitted to the Victoria University of Wellington in fulfilment of the requirements for the degree of Doctor of Philosophy Victoria University of Wellington 2013 2 Abstract Personality disorders are common among high-risk offenders. These disorders may have relevance for their risk of offending, and they are likely to present barriers to their engagement in rehabilitation programmes. Co-morbidity between personality disorders—and the high frequency of clinical disorders in general—in offender samples complicate research on personality disorder in offender rehabilitation. One approach to understanding this heterogeneity is to use cluster analysis (CA). CA is an empirical strategy which is used to identify subgroups (clusters) of individuals who have similar scores on the variables used in the analysis. It has been used to empirically identify different patterns of personality and clinical psychopathology among incarcerated offenders. Two profiles frequently emerge in cluster analytic research on offender psychopathology profiles: an antisocial/narcissistic profile and a high-psychopathology profile. However, previous research has not empirically examined whether the identification of these profiles has clinical relevance for offender rehabilitation; that is, whether the profiles are simply descriptive, or whether they can provide useful information for the management and rehabilitation of offenders. In the current research, I used data collected from high risk offenders entering prison- based rehabilitation programmes to investigate the clinical utility of psychopathology clusters. Using a self-report measure of personality and clinical psychopathology—the Millon Clinical Multiaxial Inventory III—I identified three clusters: a low-psychopathology cluster (26% of the sample), a high-psychopathology cluster (35% of the sample), and an antisocial/narcissistic cluster (39% of the sample). -
Adults Living with Autism Spectrum Disorder
A d u l t s L i v i n g with Autism Spectrum Disorder : Self Perceived Traits of Autism, Marital Quality, Parenting Competency and Anxiety Symptoms Winnie Yu Pow La u B. Com.; B. A. (Hons); M. Ed. (Dist); PGDip (C&F Psyc) A thesis submitted for the degree of Doctor of Philosophy at The University of Queensland in 2015 School of Psychology Abstract Autism Spectrum Disorder (ASD) are life-long conditions characterised by socio- communication deficits and stereotyped behaviours (American Psychiatric Association, 2013). To date, little is known about experiences of adults living with ASD, especially for those who manage to develop couple relationships and become parents (Howlin & Moss, 2012). This research examines the associations between self-perceived traits of autism and marital quality, parenting sense of competency and anxiety symptoms in adults affected by ASD. Uniquely, the sample encompasses 1) adults diagnosed with ASD whose children also have diagnosis of ASD; 2) non-ASD diagnosed parents who have children diagnosed with ASD and; 3) non-ASD parents who have typically developing children. Parents of children diagnosed with ASD are particularly targeted for their susceptibility to tendency towards autism (Bernier, Gerdts, Munson, Dawson, & Estes, 2011), and their distinctively high prevalence of psychiatric illness and marital breakdowns (Benson & Kersh, 2011; Hayes & Watson, 2013). Effects of child versus parental traits of autism were considered simultaneously. The thesis entails five empirical studies of which four have been published in peer- reviewed journals and one currently under review. Study 1 (chapter 5) investigated the associations between adult attachment style, marital quality and parenting satisfaction in adults formally diagnosed with Asperger’s Disorder/Asperger’s Syndrome (AS; a higher functioning variant of ASD). -
Living with Asperger's Syndrome - the Phenomenon Of
Living with Asperger's syndrome - the phenomenon of "not quitefitting in" Suzannah Marie Portway Submittedto City University for the degreeof Doctor of Philosophy St. Bartholomew's School of Nursing and Midwifery October 2006 Table of Contents Acknowledgments 5 Declaration 6 Abstract Chapter one: Introduction 8 1.1 Introduction 9 1.2 Background to the study 9 1.3 Study aim 10 1.4 Rationale for grounded theory methodology 11 1.5 A 'nursing' study 11 1.6 Terms of reference 13 1.7 Structure of thesis 15 1.8 Summary 19 Chapter two: Stock of knowledge: Asperger's syndrome 20 2.1 Introduction 21 2.2 The place of the literature in groundedtheory 22 23 2.3 Asperger's syndrome- historical context debate 29 2.4 Asperger's syndrome- current 2.5 Overview of current researchliterature 33 2.6 Personalexperiences of living with Asperger's syndrome 46 2.7 Gapsin the researchknowledge 53 2.8 Summary 55 Chapter three: Methodology 56 3.1 Introduction 57 3.2 Groundedtheory methodology 57 3.3 Methods 63 3.4 Evaluation of the study 82 3.5 Summary 88 Chapter four: Ethical reflections 89 4.1 Introduction 90 4.2 Planning an ethical study 90 4.3 Dilemmas of data collection 97 4.4 Researcher-participantrelationship 107 4.5 Ethical approval 112 4.6 Impact on researcher 115 4.7 Summary 118 2 Chapter five: Findings - young adults 120 5.1 Introduction to the findings 121 5.2 The core category- not quitefitting in 122 5.3 How young adults feel about themselves 123 5.4 How young adults appearto others 129 5.5 How young adults behave 134 5.6 How othersreact 142 5.7 Summary