November 17-20, 2019

4th Ringberg Symposium on Giant Biology

Ringberg Castle, Tegernsee, Germany MAX-PLANCK-GESELLSCHAFT - Scientific Program -

Sunday, November 17 Monday, November 18 - continued

15:00 Arrival, Coffee & Cake 11:30-12:00 Steven Wilhelm 16:00 Welcoming Remarks University of Tennessee, USA The Proteome and Structure of the AaV 16:15 - 17:15 Alexandra Worden Particle: a Virus With a Sweet Tooth MBARI, USA & GEOMAR Kiel, Germany A Sea of Giant 12:00 - 12:30 Jim Van Etten University of Nebraska, USA 17:30 - 20:00 Poster Session Chloroviruses Encode Many Sandwiches & Beverages Glycosyltransferases

Monday, November 18 12:30 Lunch

08:00 - 09:00 Breakfast Genetics and Biology Chair: Corina Brussaard Diversity of Giant Viruses Chair: Thomas Hackl 14:00 - 14:30 Jean-Michel Claverie IGS Aix-Marseille University, France 09:00 - 09:30 Ruth-Anne Sandaa A Spectacular Anomaly in the 4-mer University of Bergen, Norway Composition of the Giant Diversity of Giant Viruses Infecting Haptophytes 14:30 - 14:45 Matthieu Legendre 09:30 - 10:00 Grieg Steward IGS Aix-Marseille University, France University of Hawai’i Mānoa, USA The DNA Methylation Landscape of Giant Viruses in the Sea: Why Be Big? Viruses

10:00 - 10:15 Keizo Nagasaki 14:45 - 15:00 Motohiro Akashi Kochi University, Japan Tokyo University of Science, Japan How a ‘Small Society’ For ‘Giant DNA Replication, Repair, and Evolution of Viruses’ Started a Quarter Giant Viruses of a Century Ago 15:00 - 15:15 Rodrigo Rodrigues 10:15 - 10:35 Coffee Break Federal University of Ouro Preto, Brazil Trapping the Enemy: Vermamoeba Structure of Giant Virus Particles Vermiformis Circumvents In Memoriam Michael Rossmann Mariensis Dissemination by Enclosing Chair: Dennis Bamford with short intro Viral Progeny Inside Cysts

10:45 - 11:00 Chuan Xiao 15:15 - 15:45 Coffee Break University of Texas at El Paso, USA In Memoriam Michael Rossmann Host-Virus(-) Interactions Chair: Eva Lievens 11:00 - 11:30 Thomas Klose Purdue University, USA 15:45 - 16:00 Steven Short High-resolution Structures of Large University of Toronto Mississauga, Canada dsDNA Viruses and What We Can Learn The CpV System: Two Viruses, Three from Them , and One Host?

Monday, November 18 - continued Tuesday, November 19 - continued

16:00 - 16:30 Chantal Abergel 11:00 - 11:30 Eugene Koonin IGS Aix-Marseille University, France National Institutes of Health, USA Exploration of the Propagation of Giants and Dwarfs in All Branches of the Within NCLDV Reveals a Unique Example of Commensalism in the Viral World 11:30 - 12:00 Mart Krupovic Institut Pasteur, France 16:30 - 17:00 Matthias Fischer Chimeric Scenario for the Origin of Max Planck Institute for Medical Research, Viruses Germany Endogenous Virophages Populate the 12:00 - 12:15 Curtis Suttle Genomes of Cafeteria Roenbergensis University of British Columbia, Vancouver, Canada 17:00 - 17:30 Assaf Vardi Viruses – Unlocking Secrets of the Most Weizmann Institute of Science, Israel Abundant ‘’ on Earth Individuality in Host-Virus Interactions in the Ocean 12:30 Lunch

17:30 Guided Tour of Ringberg Castle Free Afternoon (Hiking, Discussions, Sports, etc.) 18:30 Dinner 16:00 - 16:30 Coffee Break 20:00 Podcast Recording ”This Week in Virology” , Isolation & Ecology With Vincent Racaniello, Rich Condit, In Memoriam Disa Bäckström Nels Elde & Guests Chair: Jeffrey Blanchard

16:30 - 17:00 Frederik Schulz Tuesday, November 19 Joint Institute, USA Global Diversity of the Megavirales as 08:00 - 09:00 Breakfast Determined by Metagenomic Analysis

Evolution of Nucleocytoplasmic 17:00 - 17:15 Bernard La Scola Large DNA Viruses IHU Aix-Marseille University, France Chair: Curtis Suttle Running After Metagenomics: New Strategies and New Tools to Discover and 09:00 - 09:30 Rich Condit Study New Giant Viruses University of Florida, USA 17:15 - 17:30 Poxviruses: A Window on the World of Hiro Ogata Kyoto University, Japan NCLDVs Global Genetic Data Reveal Lineages of 09:30 - 10:00 Nels Elde Giant Viruses and Other Eukaryotic University of Utah, USA Viruses Associated With Carbon Export Poxvirus Evolution: A Big Virus Among Efficiency Giants 17:30 - 18:00 Philippe Colson IHU Aix-Marseille University, France 10:00 - 10:15 Natalya Yutin National Institutes of Health, USA Giant Viruses in Humans Comparative Genomics of Fish 18:00 - 18:30 Provides Insights into Lutz Becks University of Constance, Germany Host Adaptation The Molecular Evolution of Eco- 10:15 - 10:45 Coffee Break Evolutionary Dynamics in a Coevolving Host-Virus System 10:45 - 11:00 Morgan Gaia CEA Genoscope, France 18:30 Conference Dinner The Co-Evolution of NCLDVs and Their Role in Eukaryogenesis 20:00 Open Mic (Music Room) - Japanese Songs - Virus Opera - Paint Your Virus

Wednesday, November 20 Version:16-November-2019

08:00-09:00 Breakfast Contact: [email protected]

Biochemistry We gratefully acknowledge Chair: Sarah Duponchel support of this meeting by:

09:00 - 09:30 Gerhard Thiel Technical University Darmstadt, Germany Viral Membrane Transport Proteins: They are Everywhere

09:30 - 10:00 Jochen Reinstein Max Planck Institute for Medical Research, Germany Illuminating Virus-Like Particles - Probes and Tools for Visualizing Mavirus Assembly and Infection

10:00 - 10:15 Yuejiao Xian University of Texas at El Paso, USA The Roles of Electrostatic Interactions in Assembly Mechanisms of Giant Icosahedral Viruses

10:15 - 10:30 Guy Schleyer Weizmann Institute of Science, Israel Mass Spectrometry Imaging of a Viral Plaque Reveals a Metabolic Shift in Emiliania Huxleyi

10:30 - 11:00 Coffee Break

11:00 - 12:00 Final Discussion

12:00 Departure