Innate Immune Activity Is Detected Prior to Seroconversion in Children
Diabetes Page 2 of 111 Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility Henna Kallionpää,1,2,19,* Laura L. Elo,1,3,* Essi Laajala,1,4,5,19,*, Juha Mykkänen,1,6,18,19 Isis Ricaño- Ponce,7 Matti Vaarma,8 Teemu D. Laajala,1 Heikki Hyöty,9,10 Jorma Ilonen,11,12 Riitta Veijola,13 Tuula Simell,6,19 Cisca Wijmenga,7 Mikael Knip,14−16,19 Harri Lähdesmäki,1,4,19 Olli Simell,6,18,19 and Riitta Lahesmaa1,19 1Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, FI-20521 Turku, Finland. 2Turku Doctoral Programme of Biomedical Sciences, FI-20520 Turku, Finland. 3Biomathematics Research Group, Department of Mathematics, University of Turku, FI-20014 Turku, Finland. 4Department of Information and Computer Science, Aalto University School of Science, FI-00076 Aalto, Finland. 5The National Graduate School in Informational and Structural Biology, FI-20520 Turku, Finland 6Department of Pediatrics, University of Turku, FI-20014 Turku, Finland. 7University of Groningen, University Medical Centre, Department of Genetics, Groningen 9700 RB, The Netherlands 8Deparment of Signal Processing, Tampere University of Technology, FI-33101 Tampere, Finland. 9Department of Virology, University of Tampere, FI-33014 Tampere, Finland. 10Fimlab Laboratories, Pirkanmaa Hospital District, FI-33520 Tampere, Finland. 11Immunogenetics Laboratory, University of Turku, FI-20014 Turku, Finland. 12Department of Clinical Microbiology, University of Eastern Finland, FI-70211 Kuopio, Finland. 13Department of Pediatrics, University of Oulu and Oulu University Hospital, FI-90014 Oulu, Finland. 14Children’s Hospital, University of Helsinki and Helsinki University Central Hospital, FI-00014 Helsinki, Finland.
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