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Inside2015–2016 Boston University College of Health & RehabilitationSARGENT Sciences: Sargent College

THE BIOMECHANICS OF MOTION

HOW A SIMPLE EXERCISE COULD KEEP YOUR BODY MOVING IN HARMONY

+ Triumph Over Traumatic Brain Injury, P 6 An Auditory , P 9 Understanding a Rare Disorder, P 10 Contents 2015–2016

DISCOVERY IN THE WORLD + STUDENT EXPERIENCE

9 13 20 THE BIOMECHANICS OF MOTION 14 An Auditory Illusion Kids in Context On Their BEST Behavior How the language we A tool that helps A Sargent partnership speak determines youth with intellectual with the Museum of the way we hear disabilities record Science, Boston, flips the How a simple their impressions conversation about autism exercise could keep your body moving ONLINE EXTRAS in harmony ALSO IN THIS ISSUE

2 Dean’s Message From Classroom to Community 3 Snapshots Watch a video of Sargent students on the service learning trip to Peru at go.bu.edu/sargent/inside-sargent. 26 Grant Awards Faculty Honors 30 Faculty in Print Keep track of Sargent faculty achievements at 33 Sargent at a Glance bu.edu/sargent/news-releases. A Source for Research News Bookmark bu.edu/sargent for regular research updates. Current work includes a study on how racial disparity is narrowing in cancer mortality. Take a Quiz Why would two people hear the same notes differently? Find out, and compare your auditory acumen, at go.bu.edu/sargent/inside-sargent.

Dean Produced by Boston University Christopher A. Moore, PhD Marketing & Communications InsideSARGENT Communications Manager About 2015–2016 Stephanie Rotondo InsideSARGENT is a publication of Boston University College of Health & Editor Rehabilitation Sciences: Sargent College. Lara Ehrlich (UNI’03) For additional copies or more information 6 10 18 22 Contributors about BU Sargent College, contact Joel Brown, Julie Butters, Leslie Friday Stephanie Rotondo at [email protected] (COM’07), Mara Sassoon, Susan Seligson, or 617-353-7476. Visit us at Triumph Over Trauma Understanding SMS Change of Plans Fighting for a Future and Andrew Thurston bu.edu/sargent. Project CAREER helps A language researcher Students with serious psy- This tool could encourage Follow BU Sargent College on: students with traumatic brain aims to improve diagnosis chiatric challenges return to Designer women of low socioeconomic Hy Zhitnik Boston University is an equal opportunity, injuries succeed in college and treatment of a rare status–and all of us–to eat school with support from the facebook.com/busargent affirmative action institution. disorder healthier Niteo program instagram.com/busargent Cover photograph twitter.com/busargent Tara Moore/Stone/Getty Images Printed on FSC-certified paper. Please recycle this publication.

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Inside gent—whose research andclinicaleffortshave enhancedthe rent andfutureleadersofourprofession—righthereatSar their careers, andbecomeleadersintheirprofession. opportunity to elevate their level of clinicalpractice, advance ual Physical Therapy offerslicensedphysical therapists the (OTD). Similarly, ournew Fellowship inOrthopaedic Man Training (MSAT) andtheDoctorofOccupational Therapy professional requirements:theMaster ofScienceinAthletic has introducedtwonewprogramstostay aheadofimminent responsibilities inmany ofthehealth professions, Sargent In keeping with the rapidly increasing expectations and tion’s CareerAward. professor toreceive theNationalScienceFounda Cara StepphasbecomethefirstCollege Sargent Jennifer Gottlieb received aFulbright Award and some oftheworld’s most prestigious organizations: ulty continuetobehonoredwiththesupportof and experts around the world. In addition, ourfac inthoughtfuldiscussionswithourpeers and engage was anopportunitytoshareouruniqueexpertise ference, Health Matters, inSeptember. Thisevent great start virtualcon withourfirstCollege Sargent Sargenta . Thenewacademicyearhasgotten offto It’s apleasuretointroduceanother issueofInside Dear Friends, Dean’s Message SARGENT This issueofInsideSargent highlightsmany ofthecur

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2015–2016

| bu.edu/sargent ------Dean andProfessor Christopher A. Moore Best wishes, the presentationsatbu.edu/healthmatters. and ifyoumissedourHealth Matters conference,youcanwatch touch! Follow Sargent’s latest andevents news atbu.edu/sargent, year arestill freshinourminds. It’s theperfecttimeforustobein the yearaheadisfullofpromise,andaccomplishmentslast syndrome.Smith-Magenis gling themysteries development inchildrenwith oflanguage for usewithyouthdisabilities, whileanother isuntan one ofournewPhDgraduateshascreatedanassessment tool dents aredeveloping innovative newresearchoftheirown: our habitswhen we’refindings to change young.Andour stu cal therapy inpreventing disabling hipinjury, usingresearch unaddressed—to remainin,orreturn to, university. dents withmentalillness—whose needsmightotherwise be Psychiatric Rehabilitation’s Niteoprogramassistsstu college in publichousingachieve theirnutrition goals. TheCenterfor ums forchildrenwithautismandhave helpedwomenliving lives ofothers. These programs have improved accesstomuse of Inside issue “This the lives of others.” have efforts enhanced clinical and research here at Sargent—whose our profession—right futureand leaders of many of the current Sargent As always, fallisoneofourmost exciting timesatSargent; You’ll alsoreadinourcover story abouttheroleofphysi highlights - - - - -

DAN AGUIRRE

STEVE PRUE about thepartnership.” tions,” says Ellis. “We’re very excited across numerousneurological condi high-caliber, outpatienttraining rigorous “in ordertoaddabroader, extremely Network’s Medford Outpatient Center— Rehabilitation institution—Spaulding CNR isjoiningwithasecondprestigious tion andinintensive care.Andin2015, experience inanacuteneurologyrota Center (BIDMC)provides residentswith tion withBeth Israel DeaconessMedical ners, Ellissays. Theprogram’s collabora it’s criticaltohave top-notch clinicalpart 30 hoursofclinicaltrainingperweek,so programperformapproximatelydency training.”specialized residency toward themedicalmodel,wherethereis “So, physical therapy ismoving more & athletic traininganddirectorofCNR. assistant professorofphysical therapy an everyday job,” says Ellis(MED’05),an in difficult to get mentoringandtraining there aremorethan25. programs intheUnitedStates. Now were just afewother neuroresidency initial groupofstudents in2011, there the first inNewEngland—enrolledits Center forNeurorehabilitation(CNR)— increasingly popular. WhenSargent’s develop expertclinicians, have become grams, whichofferspecialized trainingto applications forjust 2spots. desirable, situation:shehadreceived 33 Ellis foundherselfinadifficult,albeit cal TherapyProgram,Terry Residency dents forthisyear’s NeurologicalPhysi WHEN IT CAME TIME NEW PARTNER AN IMPRESSIVE PROGRAM GETS NEURORESIDENCY COMPETITIVE SARGENT’S Residents inSargent’s neuroresi “In thefast paceofhealthcare,it’s Physical therapypro residency to selecttheresi

------months ateach institution. A part BIDMC andSpaulding,spending six residents dividetheirtimebetween mentor tothe2015 residents. now worksatSpauldingMedford andisa program,SaraCrandall(’10,’12),dency nario, agraduateofSargent’s neuroresi BU.” InwhatElliscallsa“full-circle”sce an academicinstitution aswonderful “and we’re delightedtocollaboratewith tion areality. “Terry isamazing,” shesays, closely withEllistomake thecollabora Brace andProsthetics Clinics, worked supervisor andadirectorinSpaulding’s Pezzini, theneurologyprogramclinical UNIQUE “THE SAME SPACE.” ALLIN THE AND EDUCATION CLINICAL CARE, DO RESEARCH, IS,THING WE During the yearlong program, the During theyearlongprogram, the The excitement ismutual.Lisa —TERRY ELLIS

- - - - bu.edu/sargent unique thingis, wedoresearch, clinical in individualswithParkinson’s. “The disability andimprove physical function early exercise intervention toreduce research atCNR,whichfocuses onusing Physical Therapy program. clinical courseinSargent’s Doctor of in thelabcomponentofaneurological gain teachingexperienceby instructing professional network. Residentsalso pate indidactictrainingandbuildtheir country, allows theresidentstopartici programsfromacrossthe roresidency Consortium, whichbringstogetherneu Physical Therapy ProfessionalEducation nership withCalifornia’s Neurologic The residentsassist Ellisinher

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care, and education all in the same space. people with Parkinson’s. With the app, and allows us to optimize the benefit In summer 2015, Sargent undergraduate and graduate students So there’s never a gap between findings patients watch videos of their CNR ses- of exercise by increasing the challenge embarked on a service learning trip to Peru. At an altitude of 11,000 feet, and translation to clinical practice,” she sions on a mobile device, which allows level over time.” they experienced firsthand the traditional Andean way of life, from a says. “Then we do outreach programs to them to continue their exercises at Ellis is confident that the neuroresi- remote farming village to the Inca capital of Cusco. disseminate our research findings to the home. They rate the difficulty and pain- dency program’s combination of research Supervised by Sargent faculty, students had the opportunity to see broader scientific community.” fulness of each exercise using a sliding experience at CNR, diverse clinical health care at work in a developing country; they learned about tradi- This year, the residents are help- scale on the app. “We can now remotely exposure at BIDMC, and the new partner- tional medicine and visited rural community clinics, as well as public ing Ellis conduct a yearlong research change people’s exercise programs,” ship with Spaulding will make the next and privately funded hospitals. trial testing the benefits of a mobile app Ellis says. “We’ve found that monitor- generation of physical therapists even in making exercise more accessible to ing progress helps people keep going stronger.—Mara Sassoon

APHASIA COMMUNITY TOP AWARDS Julie Starr, a clinical associate pro- fessor of physical therapy & athletic GROUP CELEBRATES training, received the American Physical Sudha Arunachalam, an assistant 25TH ANNIVERSARY Therapy Association (APTA) Linda professor of speech, language & Crane Memorial Lecture Award, which sciences, received the 2015 Marion and In 1990, speech-language patholo- honors an APTA member who has Jasper Whiting Foundation Fellowship gist Jerome Kaplan launched a series demonstrated excellence in research, Award. Sara Brown, a clinical associate of monthly meetings at Spaulding clinical, or academic practice. Cara professor of athletic training, received Rehabilitation Hospital to offer sup- Stepp, an assistant professor of speech, the National Athletic Trainers’ Associa- port to those suffering from aphasia, language & hearing sciences, was named tion Most Distinguished Athletic Trainer a language disorder that often results a Hariri Institute 2014 Junior Faculty Award. Jennifer Gottlieb, a research from stroke, traumatic brain injury, or Fellow and is the first professor at Sar- assistant professor of occupational ther- neurological diseases. gent to receive a Faculty Early Career apy, received a Fulbright Scholar Award Kaplan’s Aphasia Community Development Award from the National for the 2015–2016 academic year. Group moved to BU, and expanded into Science Foundation. Sargent’s Aphasia Resource Center (ARC), which offers educational, social, and clinical resources. In addition to facilitating weekly topic-specific groups, Kaplan still leads the free NEW FACULTY AND PROMOTIONS monthly meetings for up to 100 people. Thanks to the group, says Swathi New Faculty Erin Riley, clinical assistant profes- Kiran, a professor of speech, language Laura Driscoll, clinical assistant profes- sor, department of physical therapy & & hearing sciences and the center’s sor, department of physical therapy & athletic training research director, “the ARC is now athletic training Basilis Zikopoulos, assistant professor, one of the strongest community department of health sciences resource centers in the country, and Bria Dunham, clinical assistant profes- it fulfills three important missions: sor, department of health sciences providing exceptional services for Anne Escher, clinical assistant profes- Promotions patients, training the next generation sor, department of occupational therapy Elizabeth Hoover, clinical associ- of clinicians, and serving as an impor- Daniel Fulford, assistant professor, ate professor, department of speech, tant test bed for clinical research department of occupational therapy language & hearing sciences and clinical in aphasia.” Mary Beth Holmes, clinical assis- director of the Aphasia Resource Center To date, the group has held more tant professor, department of physical Eileen O’Keefe, clinical professor, than 300 sessions and served approxi- therapy & athletic training department of health sciences and direc- mately 12,000 people. The Community tor of the program in health science Group celebrated its 25th anniversary Robin Newman, clinical assistant profes- > WebExtra this June. sor, department of occupational therapy Watch a video of the trip at go.bu.edu/sargent/inside-sargent. ALAN WONG

4 InsideSARGENT | 2015–2016 | bu.edu/sargent bu.edu/sargent | 2015–2016 | InsideSARGENT 5 DISCOVERY

“There is a real void in services for students with TBI in helping them transition from being in a student role, graduating from school, and then obtaining a job,” says Karen Jacobs, a clinical professor of occupational therapy and principal investigator for the BU subcontract. “There are limited resources helping them with that transition period. TRIUMPH Every one of these students could benefit from the intense ­mentoring and advising Project CAREER offers.” OVER TRAUMATIC Every year roughly 1.7 million Americans sustain a TBI, often from a car or sports accident or a violent assault. This group also includes soldiers who have been injured by BRAIN INJURY explosive devices. Symptoms vary, but people living with TBI often experience trouble with memory, concentration, and organization; may be irritable, tired, or depressed; and may endure punishing headaches. They may find it hard to navigate and understand complex systems and initiate new tasks. And they often fail to connect with support services effectively, or have difficulty establishing and maintaining PROJECT CAREER PREPARES relationships. Ongoing cognitive impairments have histori- cally made it more difficult for people suffering from TBIs to STUDENTS FOR RIGORS OF find—and keep—a job. Students develop a number of strategies to manage their SCHOOL AND WORK TBI. They may listen to audiobooks if reading is challenging, request note-takers or extra time for tests if their concentra- BY LESLIE FRIDAY tion lags, and post sticky notes everywhere to remind them- selves of appointments, exams, or medication they could otherwise forget. These strategies might help them get into school, Jacobs says, but they’ll need additional support to do well. Students enrolled in Project CAREER receive an individu- alized plan designed to address their specific needs. Amanda Nardone (’13), a BU technology and employment coordina- tor, works with students to assess their academic difficulties, employment history, and comfort level with technology, as well NNA SAUCIER’S LIFE changed in an instant during Instead of giving up, Saucier says she got mad: “I forced “THERE IS A REAL VOID as where the student would like more support. (Every Project her sophomore year of high school. She remembers myself to get better.” She underwent neurological rehabilita- CAREER student receives an iPad and a budget for apps.) If zipping across a soccer field to head off a boy on the tion, got a tutor, and enrolled in honors and AP courses her IN SERVICES FOR students have difficulty with organization or memory, Nardone opposing team who was fast-breaking toward the junior year. “People get injuries and they think that’s it,” uses calendar and planner apps such as iOS Calendar, Planner- goal. The center defender of her coed team, Saucier she says. “That was never an option for me. I know what I’m STUDENTS WITH TBI. . . . Plus, Week Cal, or iStudiez. For time management, she recom- executed a perfect slide tackle (the first in her career) capable of, and that’s what I had to get back to.” She gradu- mends 30/30, an app that creates a list of tasks and specifies Ato prevent the point, but her opponent flipped and landed ated among the top students in her class, applied to BU, and EVERY ONE OF THESE a time limit for each item. For recording lectures and note- knee-first on her temple. started her freshman year in fall 2014. While her condition has taking that syncs with the recording, she suggests Notability or She continued to play the minute left in the game before improved, she still suffers from crippling headaches and has Evernote. For students experiencing anxiety, she recommends collapsing off the field, suffering from the worst of several trouble with organization, time management, and memory. STUDENTS COULD Breathe2Relax or Yoga Studio. concussions she’d had during her career as a four-sport athlete. Just after she arrived on campus, Saucier visited Disabil- “I do my best to individualize this program and meet stu- Saucier (CAS’18) was rushed to the hospital and in the days ity Services. Staff there recommended she enroll in Project BENEFIT FROM THE dents where they are,” says Nardone, who sees each student for following, she couldn’t walk, had no energy, and experienced CAREER, a program that uses assistive technology and a couple hours every other week or as needed. memory issues. She was placed on morphine for three days to vocational rehabilitation to improve the academic and employ- INTENSE MENTORING For Saucier, the note-taking and organization apps have control her throbbing headaches. ment success of college undergraduates with traumatic brain been invaluable. She says Notability has given her a “confidence Plagued by fatigue, an inability to concentrate, and injury (TBI). She is now among 40 part- and full-time students AND ADVISING PROJECT boost” in lecture-style chemistry and calculus courses. And a ­persistent headaches, Saucier was unable to return to enrolled in the program, which is a partnership among Kent yoga app is helping her deal with still-frequent headaches. school full time for several months. It was enough to drive State University, West Virginia University, and JBS Inter- CAREER OFFERS.” One of the stated goals of the project is to improve employ- the straight-A student and class president crazy. “I got national, Inc. The program is being funded by a five-year, ment outcomes for students suffering from TBI. Nardone really good at coloring,” she says. The walls of her house $2.5 million grant from the National Institute on Disability, —KAREN JACOBS matches students with mentors in their desired field so quickly filled with artwork—a daily reminder of her slow Independent Living, and Rehabilitation Research (NIDILRR) students can better transition from academics to professional

but steady progress. (formerly NIDRR). SHOLA FRIEDENSOHN BY ILLUSTRATION PHOTO careers. Once matched, the student and mentor keep in touch

6 InsideSARGENT | 2015–2016 | bu.edu/sargent bu.edu/sargent | 2015–2016 | InsideSARGENT 7 DISCOVERY STUDENT EXPERIENCE

■ Through Project CAREER, An Auditory Illusion “We are interested in Amanda Nardone (’13) (left) and Does how we speak determine how we hear? how brains change Karen Jacobs support 40 part- and full-time students with TBI. BY LARA EHRLICH with experience and “I DO MY BEST TO how our experiences INDIVIDUALIZE predispose us to esearcher Elizabeth Petitti sits in a certain auditory skills.” quiet lab, opens her laptop, and plays —Tyler Perrachione THIS PROGRAM R two musical notes. Some would hear the notes rise in pitch, while others would AND MEET hear them fall. Why would two people hear These results led Petitti and Perra- the same notes differently? The answer may chione to wonder if the difference in pitch is improve our understanding of how our audi- grounded in our earliest language acquisition, STUDENTS WHERE tory system develops, and may help speech- or if other experiences can also affect how language pathologists who work with people our brains process sound. For instance, THEY ARE.” who have hearing impairment. would musicians—who also rely on pitch— Petitti says the answer comes down to perceive sound the same way as tone- — AMANDA NARDONE (’13) the way our brains perceive two components In their auditory study, Tyler Perrachione language speakers?­ that make up sound: fundamental frequency and Elizabeth Petitti (’15) found that native When they put the question to the test, tone language speakers and native-English and harmonics. speakers hear pitch differently. Petitti and Perrachione found that neither A note’s fundamental frequency is the the age at which a musician began study- primary element of sound from which our “There’s no right answer,” Perrachione ing nor the number of years he’d practiced brains derive pitch—the highness or lowness says. “Pitch only exists in our minds. It’s a impacted his perception of pitch. To Petitti, of a note. Harmonics give a note its timbre, perceptual quality.” So, how exactly do we this suggests the way we listen is determined by email, phone, or Skype, or they meet in person to discuss She says that since the project launched, it has become the quality that makes instruments sound determine pitch? It turns out the language we by our earliest brain development. While you questions from course selection to internship opportunities. apparent that there are few support groups in the area for indi- distinct from one another. speak plays a role. may begin learning an instrument as early Nardone also helps students find internships, research and viduals with TBI. She and Nardone are working on creating a Many sounds in the world are made up Petitti and Perrachione theorized that as three, “you start language learning from apply to graduate school programs, and polish their résumés and support group on or near the BU campus to provide additional of these tones, whether you strike a key on a individuals who grew up speaking a tone birth,” she says. “So your is cover letters. She follows students for up to a year after graduation support for them and their families. keyboard, play a note on a clarinet, or say a language like Mandarin would perceive pitch influenced by the language you are exposed to see if they need further assistance landing a job, or to offer sup- As for Saucier, she’s embarked on an ambitious pre-med letter, says Petitti (’15), who graduated from differently than those who grew up speaking to from day one.” port for those already employed. ­curriculum, designing a degree that combines neurology, Sargent with a master’s in speech-language a non-tone language like English. In Mandarin, It’s not just theoretical. “Big picture: Jacobs recognizes that while Project CAREER helps under- ­psychology, sociology, and medical anthropology. She wants pathology. Our brains expect the fundamental for example, a word often has several mean- we are interested in how brains change graduates, graduate and certificate program students would to encourage more students to enroll in Project CAREER. “The and the harmonics to be present in any given ings, depending on how the speaker employs with experience and how our experiences also benefit from the services, and she hopes the next round of reason I’m doing so well in my classes,” she says, “is because of note. But when some of this information pitch; mā (with a level tone) means “mother,” predispose us to certain auditory skills,” funding will allow her and her colleagues to address that gap. Project CAREER.” IS drops out, “the way you perceive the note can while mă (which drops, then rises in tone) Perrachione says. This understanding could change in surprising ways,” says Petitti’s men- means “horse.” “help us better understand the opposite, tor, Assistant Professor Tyler Perrachione, a To test this theory, Petitti invited 40 native- when things don’t work quite right,” such as Peter Paul Career Development Professor and English speakers and 40 native tone language when a person has a disorder like CONQUERING CONCUSSIONS ■ 300,000+ director of the Communication Neuroscience speakers to participate in a study, which she (tone deafness). annual sports-related concussions in the US Research Laboratory. and Perrachione presented at the International Petitti underscores the study’s potential ■ 10%–15% Petitti explains that when she removes Congress of Phonetic Sciences in August 2015. clinical impact; in her career as a speech- In 2015, Boston University’s Ryan Center for Sports Medicine of concussions result in persistent symptoms will open a Concussion Management Center to meet the the fundamental from a tone (using signal Each participant listened to 72 pairs of tones language pathologist, she intends to work with needs of a growing patient population. Headed by Douglas ■ 25 processing software), and then plays that stripped of their fundamental frequencies, clients who have hearing impairments, which Comeau, a School of Medicine assistant professor of family is the age at which the brain’s frontal lobes stop developing note, the listener’s brain automatically sup- and then indicated if the tones were moving will involve teaching them to perceive and use medicine and director of sports medicine, the facility will pro- plies the pitch. People’s brains deliver this up or down. pitch. This ability is “crucial when you’re teach- ■ vide concussion care to the public, from testing and clinical 34% information in different ways: they either fill Petitti and Perrachione found that ing how to ask a question, and how to use pitch of college football players sustain concussions treatment to rehabilitation and prevention education. in the frequency—simi- language does change the way we hear. to signal the difference between words,” she The new center aims to make patient care more streamlined ■ 60% lar to the way the brain would compensate for Individuals who grow up speaking English are says—all skills we typically begin to develop by offering all services under one roof, says Comeau, who is also of college soccer players sustain concussions a blind spot in our eye—or they determine the more attuned to a note’s harmonics, while the early and unconsciously. For a seemingly the medical director of the Ryan Center and director of the BU ■ pitch from the harmonics. tone-language speakers are more attuned to simple ability that most of us take for granted, primary care sports medicine fellowship. “It’s very exciting that 36% of college athletes suffer multiple concussions Here’s where it gets interesting: when its fundamental. So, when a note is stripped there is much at play. IS we are able to treat high school and college students, full-time two different tones that have been stripped of of that component, they’re more likely to athletes, and weekend warriors,” he says, “and provide the same ■ 70 mph their fundamentals are played in succession, derive pitch by supplying the missing funda- treatment the pros would get.”—MS is the impact speed of a soccer ball > WebExtra some listeners hear their pitch rising, and mental than by listening to the harmonics still Take the auditory illusion quiz at

JACKIE RICCIARDI JACKIE SPENCER MICHAEL D. some hear it falling. Who’s right? present in the note. go.bu.edu/sargent/inside-sargent.

8 InsideSARGENT | 2015–2016 | bu.edu/sargent A version of this article originally appeared in BU Today. bu.edu/sargent | 2015–2016 | InsideSARGENT 9 DISCOVERY misdiagnosed asautism probes agenetic disorder often Language researcher MaxKon (’15) A BROTHER’S LOVE A RARESYNDROME, By Susan Seligson

CYDNEY SCOTT results, Kon says. Zach’s treatmentinvolved modifyinginappropriate behavior by who wasn’t diagnosed withSMSuntilhisteens, hadmixed intervention withABA involve clearinstructions, positive reinforcement,andrepeated trials. For Zach, bances andbehavior issues.) Designed forchildrenandteens, thetasks usedinABA comprehension, reading,and math. (Otherpractitionersalsoaddresssleepdistur whichtargetsskillsrelatedtoattention span,language behavior analysis(ABA), goes Study sample sizeshave been smallbecausethedisorderisnot onlyrare,itoften &hearingsciences,speech, language Lab. anddirectoroftheBUChildLanguage understood, says Kon’s mentor, Sudha Arunachalam,anassistant professorof of SMSareforscientists inanother fieldtodecipher, says Kon. development ofthefetus. Themutation’s causeisunknown, andtheprecisegenetics alteration inaDNAsequenceduringtheformationofreproductive cellsintheearly The disorderisnot typicallyinheritedandiscausedby amutation,orpermanent profile ofSMS, aconditionthataffectsan estimated 1in 25,000 peopleworldwide. ers—“He hasway morefriends thanIdo,” hisbrother says—Zach fitsthetextbook From skillstotheirrepressibleattraction thedelayed speechandlanguage tostrang A MYSTERIOUS DISORDER W lead to a targeted approach to treatment. lead toatargetedapproachtreatment. interpret written andspoken wordsdifferentlythantypicallydeveloping learnerswill Kon. He hopesthatstudying how childrenwithSMSlearntospeakandwhy they research tobetter understanding thedisorderhisfamilyoncecalled“Tourette’s Plus.” brother, Max Kon (’15),tobecomealinguist andspeechpathologist anddevote his of amutationinhisDNA. syndromerevealed Zachhasararedisordercalled Smith-Magenis (SMS),theresult himself. AfteryearsofmisdiagnosesasTourette syndrome orautism,DNAtesting “ GO TO THEM.” LAB, SMSISFAR LESS COMMON, SO INEED TO AND WE OFTENRECRUIT PARTICIPANTS TO THE WHILE AUTISM IS A MORECOMMON DISORDER Individuals whohave beendiagnosedwithSMS areoftentreatedwithapplied As ofnow, the disorder, identifiedin1986geneticists,by apairof remainspoorly Because SMSisnot widelyunderstood, thereisnospecifictreatmentforit, says The family’s struggle toidentifyandtreatZach’s disorderinspiredhisolder ­undiagnosed. wasn’t right.He hadaprotruding jaw, aprominent forehead,andflat aggressive outbursts athomeandschool.Andheconstantly hugged often unintelligible.Despitehisexuberancetoward strangers, hehad tone slackened, andwhenhedidspeakhiswordswereslurred tened features. AsZachgrew, hisspeechwas delayed, hisfacialmuscle HEN ZACHHEN KON WAS INFANT AN —MAX KON (’15) bu.edu/sargent hismother suspectedsomething

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■ Kids in Context A new survey helps youth with intellectual disabilities engage with their community BY STEPHANIE ROTONDO focusing on the “antecedent”—the conditions leading up to the “hat,” which indicates difficulty listening, hearing, or compre- behavior—rather than on the outcome. For children with SMS, hending the command, says Kon. One child pointed to a dog “this tilts the balance toward maintaining a positive, helpful when asked to point to a cat, indicating difficulty with associ- environment rather than setting expectations,” Kon says. This ating meanings and sounds. “And some children, while social t a local burger establishment, disabilities—particularly those in disadvan- treatment is frequently used to treat children with autism, but and happy enough to spend time with me, did not respond at 17-year-old Lisa* orders a drink and taged circumstances—become more involved tends to be less reliable for those with SMS, who require more all, indicating poor comprehension or an inability to recognize A fills her cup at the soda machine. in school and other social activities. individualized intervention, Kon says. my intent.” It’s a routine act for many teenagers, but Developed for those in the “transition In another, slightly more difficult test, Kon presented two performing this task without assistance is a ages” of 12 to 22, the tool will assist service SIMPLE QUESTIONS, REVEALING ANSWERS pictures‚ one of a boy kicking a ball, and one of a boy hugging milestone for Lisa, whose ultimate goal is to providers—occupational therapists, spe- Kon, a master’s student, has been working with Arunachalam a girl, and asked the participants to identify the picture in participate more fully in community living. cial education teachers, and recreational to establish the first comprehensive picture of what the SMS which the boy is hugging the girl. This test examines a child’s Lisa and five other Boston-area youth with therapists—to determine whether the young population looks like in terms of language expression and understanding of syntax, Kon explains. “Think of how compli- intellectual disabilities are taking part in field people have participated in various aspects understanding: their strengths and weaknesses, how their abili- cated English can be,” he says. Sentences as similar as “The boy research for a survey development project of an activity, including being independent, ties grow over time, and whether this growth is dependent on hugged the girl” and “The boy was hugged by the girl” require conducted by Kendra Liljenquist (’15), who working with their peers, and engaging in key the kinds of intervention they experience. what speech-language pathologists call “syntactic compre- recently graduated with a PhD from Sar- developmental activities such as collabora- Arunachalam advised Kon as he prepared the study, helping hension.” “Testing this comprehension can reflect whether gent’s program in Rehabilitation Sciences. tion and planning. The survey will also help With support from her mentor Wendy Coster him to “formulate questions and look at the disorder from a children show patterns in their syntax—passive versus active researchers and service providers better (above), Kendra Liljenquist (’15) (left) broader research perspective,” Kon says. Since Kon’s gradu- sentences, for example—or whether they understand relatively understand how different environments developed the first tool to help youth with ate education has been largely focused on clinical practice complicated sentences but can’t respond verbally with the promote growth and will assist schools and developmental disabilities self-report their experiences. as a speech-language pathologist, Arunachalam helped him same level of complexity. Tests like these also measure verbal community organizations in becoming more integrate the more clinical aspects, such as language testing and memory,” Kon adds. inclusive. survey-takers for input. She conducted in- behavior management, with the rigorous standards of research. Kon hopes his work will eventually help improve detec- Liljenquist’s survey is the first tool to depth interviewing to check the participants’ She helped Kon ensure his documentation and testing met the tion of SMS. He plans to apply to a PhD program to continue provide youth with intellectual disabilities understanding of each question, and she standards of the University’s Institutional Review Board (IRB), his research and attain a better of the range of abilities the opportunity to self-report their impres- was mindful to include youth of varying ages, which must approve all research involving human subjects. among those who have the disorder. As Kon continues his sions and experiences. Current self-report backgrounds, and disabilities. “It’s important study, he also aims to show the key differences between autism measures are often not accessible to individu- to ensure we’re not disenfranchising people,” spectrum disorder and SMS, and find ways in which treatment als who may have difficulty with abstract Coster says. “WHEN I’M GOING THROUGH A that has been effective for autism might be tailored to children thinking. “You’re asking people with cognitive Liljenquist is now implementing the tool with SMS. Ultimately, he hopes his research will enable doc- challenges to report on how they’re thinking, with organizations like Seattle Parks and ROUGH PATCH, [MAX] SAYS THINGS tors to diagnose the disorder more quickly and it will lead to a so you have to conduct testing in a different Recreation, which has asked her to evaluate LIKE, ‘ZACH, CALM DOWN, TAKE A targeted treatment that can be applied as consistently at home Throughout the summer, Liljenquist takes way,” says Liljenquist’s mentor, Professor their youth sport and teen activity programs as it is at school. the youth on trips to a restaurant, a bowling Wendy Coster, chair of the occupational ther- and expand the measure to adult populations. DEEP BREATH.’ ” —ZACH KON alley, a pottery class, and the Museum of Sci- apy department and director of the Kids in And the Special Olympics Washington has A LONG-TERM PROJECT ence, Boston, where they engage in activities Context Lab. Liljenquist’s survey is intended expressed interest in working with Liljenquist “I’m still in the preliminary phase of analysis,” says Kon, who that are new to them. Liljenquist documents to be conducted in interview format—no read- to assess its unified sports program. She In June 2014, Kon attended a conference in St. Louis, is in the process of renewing his IRB certification, which will these outings with photographs, and after ing required—“to be as accessible as possible plans to broaden the public’s access to the Missouri, where those with SMS and their families gathered enable him to continue collecting data to increase the sample each trip, interviews the youth about their to young people with a wide range of abilities,” survey by making it available for free down- to share experiences and learn about research and treatment size as well as track the same participants over time. In the experiences. The tool she has developed to says Liljenquist. “You can’t ask for a survey of load through Canada’s CanChild Centre for updates. In advance of the event, Kon emailed families on the meantime, the more kids with SMS Kon meets, the more he record their impressions—the Participatory people who can’t understand the questions.” Childhood Disability Research, an organiza- conference participant list and recruited eight children to his understands the challenges his brother, Zach, has faced. Experience Survey—features 20 questions, Her tool forgoes the rating scales common tion with which Coster and her lab regularly study. “While autism is a more common disorder and we often Now 22, Zach is a high-functioning extrovert living in a such as, “Did you do something by yourself in many instruments and features straight- collaborate. Coster credits Liljenquist’s skill in recruit participants to the lab, SMS is far less common, so I group home. A fan of the Guinness Book of World Records who’s today?” and “Was anything too hard today?” forward questions, asking participants to cultivating relationships and developing trust need to go to them,” he explains. At the four-day conference, he emphatic about people spelling his name correctly, he is on When Liljenquist asks Lisa to choose the respond with either “yes” or “no.” among service providers and the youth they conducted one-on-one testing with the children whose parents medications that have largely calmed his aggression. photo that depicts her favorite activity of the Liljenquist’s fieldwork was invaluable serve as a key reason for the tool’s success. IS had agreed to participate. At the Parents and Researchers Interested in Smith-­ day, the teen beams with pride as she selects to designing the survey. “She’s not develop- *Name changed for privacy The children, who ranged in age from 5 to 10, took part in Magenis Syndrome, or PRISMS, Building Bridges of Hope Con- the image of herself at the soda machine. ing something in the lab and taking it to the a series of tests to probe their levels of language ability and ference in 2014, Zach gave a speech to children with SMS and “When kids participate in activities like community,” says Coster. “Instead, she went comprehension. In one test, Kon held up a board depicting their families, in which he said, “My family is the rock of my life clubs or sports, they’re given the opportu- to the community and developed something Development of the Participatory Experience Survey was supported by Boston University’s Department of four pictures and asked his young participants to point to the and I love them dearly. My older brother is really helpful,” and nity to develop skills that lead to successful that from the beginning is there to meet their Occupational Therapy and School of Education, Har- objects—shovel, tree, hat—as he named them. While some has been “right there from the start. When I’m going through a transition into adulthood,” says Liljenquist, needs.” Liljenquist conducted field research vard Graduate School of Education, Boston Children’s Hospital, and the Center on Human Development and were very capable of following directions, others responded rough patch, he says things like, ‘Zach, calm down, take a deep who intends for the Participatory Experience and observation, gathered feedback from Disability at the University of Washington. It is aided by

to something close, for example, pointing to “cat” instead of breath,’ and these words will never leave my brain.” IS MIKE SPENCER, RIGHT WURZER, LEFT; RON Survey to help minority youth with intellectual parents and practitioners, and asked the a grant from the Dudley Allen Sargent Research Fund.

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BIOMECHANICS DISCOVERY

THE THE

MO TION MOTION OF BY ANDREW THURSTON IN HARMONY HOW A SIMPLE EXERCISE COULD KEEP YOUR BODY MOVING

PHOTOGRAPHER

A to ensurefewer peopleget injured inthefirst place. after akneegives outorahiplocksup—she’s pioneering rehabilitationasprevention uncovers newways ofhelpingpatients. Andherworkisn’t limitedtojust intervening biomechanics totest conventional treatmentsandexercises, Lewisconsistently that thelegdoingmoving mightnot begetting agreatworkout afterall.By using abductors, fromwheretoplacethebandhow tomove eachleg.Shealsodiscovered what’s eachsideofthebodyhaving todo?” biomechanics backinthepicture,” aretheforces, shesays ofherresearchaims. “What to stop andthink aboutwhatyou’re doingandwhereit’s actuallyworking—putalittle which way: around toes, ankles, andknees;whilestanding andsquatting. “You have full ofthebands, butnocommonguidanceontheirusage. who started her careerinprofessionalpractice.Almost every clinicandgymhasbags saysbut why?” Lewis, anassistant professorofphysical therapy & athletic training they werebeingusedinthemost effective way. began towonderwhichhipmusclesthebandswereactuallyworkingandwhether work harder—an effectthat’s alsomadethempopularat-homeexercise tools. bands, available inarainbow ofcolorsandresistance levels, forcingtheleg’s musclesto to step fromsidetoside.Asthey step, theyhave tostretch thesophisticated rubber pists loopaTheraBand,anelastic resistance band,aroundapatient’s legsandaskthem clinics, theexercise of choiceforsuchconditionsisaresisted sidestep. Physical thera (that dullacheinthekneeyoumightfeelwhenjoggingordescendingstairs). Inmany paincommoninrunnersandcyclists)patellofemoralsyndrome lems (leg a smallmuscleontheouterhip. medius, whichwrapsfromthe reartotheoutsideofthigh,tensorfascialata, side step. Thehipabductorsweregetting aworkout, fromtheposterior gluteus pitches flew, they started talkingaboutthemuscleactivityinvolved inthe Fenway up anddown ofrow afterrow astheSox tookontheArizonaDiamondbacks. Asthe In aseriesoflab-basedexercises, shedetermined thebest way torehabhip In aNationalInstitutes ofHealth–funded study, Lewistested thebandsevery Itreatedpatientsintheclinic,usuallyputbandaroundtheirankles, “When But astheysat watching Fenway Park’s sidesteppers, Lewisandhercolleague They’re thesame musclesthatcancause,amongother things, iliotibial bandprob In summer2010, CaraL.Lewisandafellow physical therapist watched theregular ERS SQUEEZE AND SIDESTEP PAST ROWHASLATECOM TORISE AS THE - DOGS,DRINKS AND WITH WHOLE THE STRAGGLERS IDLEBACK MID-INNING LEGROOM.OR WIGGLE LITTLE WHEN EARLY 20TH CENTURY, OFFER VERY SEATS, CRAMMED INDURING THE FANS DON’T SIT COMFORTABLY. THE T HISTORIC FENWAY PARK, REDSOX bu.edu/sargent

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JANICE CHECCHIO DISCOVERY

THE HUMAN MACHINE She expected to see the hip muscles working harder as the granted. Clinicians in the field aren’t always so blessed, says Fixing things runs in Lewis’ family. When she was growing up, band moved lower down the leg, but wasn’t sure if moving it Lewis. To give her students the best start and “encourage Lewis used to watch her grandfather coax car engines back to from ankle to toe would make a significant difference. a spirit of inquiry,” she urges them to play an active role in life. He was an auto mechanic—and occasional racetrack pit “From a biomechanical standpoint, when you get farther her research. crewmember—and Lewis was captivated by the combustion from the joint, you would assume you’ve increased your lever “It gives you a better appreciation for interpreting evi- engine’s ballet of valves and pistons. arm—that is, the distance from your joint—and that’s going dence,” says Lewis of involving students. “If we’re all going “I always thought being a mechanic was so cool because to increase the torque created by the band,” says Lewis. She to be evidence-based practitioners, we’ve got to understand I loved looking at how things moved, how they interacted,” explains that’s why most doorknobs are opposite the hinge the process and we’ve got to be willing to take part in that.” she says. and not in the middle. “But when you go from ankle to toe, Two Sargent students, Hanna Foley (’15) and Theresa Lee The gadgets assembled in Lewis’ Human Adaptation Lab at we weren’t really sure what was going to happen because the (’15), did much of the work on the side step study and were Sargent College—digital motion capture cameras, an electro- increase in lever arm isn’t a lot.” listed as coauthors when it was published in the Journal of myography system, signal conditioning amplifiers—shed light Orthopaedic & Sports Physical Therapy. After being involved on how components in the human machine work together. And THE POWER NEEDED TO STAND in the project, Foley changed her plans and now hopes to work they help Lewis figure out ways to prevent our bodies from After collating the results, Lewis found that for most conditions toward a career as a researcher. The study results have already breaking down. it’s better to step while squatting rather than standing and that shaped her clinical work. In the side step study, Lewis and her team of researchers the toe is the best place to put the band. “My clinical experience is in the outpatient orthopaedic placed electromyography pickups on subjects to record “the “When you go out to the toe,” she says, “the band pulls setting,” says Foley. “I implement our findings with patients electrical activity in the muscle, which then tells you how active your toes in, creating this internal rotation of your legs.” who need gluteus medius strengthening. It is very rewarding to the muscle is.” Participants also wore small reflective markers. When that happens, the external rotators—the gluteus have been a part of the research that supports the exercises I’m Ten cameras nestled close to the lab’s ceiling followed the reflec- medius on the outer pelvis and the gluteus maximus, the prescribing for real patients.” tive markers, recording the images and tracking movements most powerful hip muscle—activate to stop the toes from Lewis also hopes her students take away another impor- turning. But, importantly, the tensor fascia lata doesn’t have tant lesson: physical therapy is about diagnostics as well as x x to work as hard. treatment. When she was first studying the subject, Lewis “As you go from knee to ankle to toe, the gluteals all increase,” Cara Lewis’ grandfather made remembers, “we were talking about how people walk and I was says Lewis. “The tensor fascia lata increases from knee to ankle car engine components work one of the ones put up onstage to walk in front of everyone. in unison. She does the same but not from ankle to toe. A lot of these musculoskeletal condi- with the human machine. Not because I did it correctly, but because I didn’t know how to tions that we try to rehab, we’re trying to get more gluteal activity push off with my feet.” and not more tensor fascia lata activity. By putting the Thera- In a study with her postdoctoral mentor, Lewis discovered Band around the toe, you’re getting that.” Most home exercisers that pushing off harder from the feet when walking reduced

Incorrect Correct Incorrect using resistance bands to strengthen leg muscles should put the stress on the hip joints. She changed the way she walked, less- band around their toes for the same reason. “I REALLY THINK ening her chances of future hip and back pain. For some, the most surprising conclusion from the study “I really think physical therapists should be playing a bigger In a study using electromyography technology, Cara Lewis determined that the most effective use of the TheraBand is could be Lewis’ finding on which leg is getting the biggest PHYSICAL THERAPISTS role in prevention. If you think about it, you go to the dentist to step while squatting with the band around the toe, as workout during the side step: the one standing still. “As a bio- twice a year, you brush your teeth every day; why don’t we take opposed to positioned around the ankle or knee. mechanist it makes perfect sense to me,” says Lewis. “The leg better care of our musculoskeletal system in a similar way? you’re standing on has to stabilize your trunk; all you’re having SHOULD BE PLAYING Why don’t we go to physical therapists at least once a year to to do is move the other one. You’re really strengthening the find out what we could be doing better?” using a 3D motion capture system so Lewis could determine the leg you’re standing on more than the leg you’re moving.” The A BIGGER ROLE When it comes to hip pain, most think about seniors subject’s position and how they moved. result is one she hopes reminds clinicians—and fitness fanat- creaking along until they need a joint replacement; Lewis She asked the subjects—all healthy, so results weren’t skewed ics—to think more often about the body’s mechanics as it goes IN PREVENTION.” aims to ward off the problems before they begin. Other by existing neuromuscular conditions—to sidestep across the through common exercises. projects in her lab include a study of how male and female lab and then make their way back with a resistance band looped It’s not unusual for Lewis’ research to bring such practice- hip structure changes in adolescence and a five-year inves- around their knees, ankles, or toes. This test allowed researchers changing conclusions. In a concurrent study, she tested the —CARA LEWIS tigation of young athletic adults with hip pain. She’s also to see each leg stand and move in both directions. They’d then do mechanism of another popular drill, the single leg squat—one planning to collaborate with a mechanical engineer to model it all again (and again) with the band in a different position. They leg off the floor, the other bending at the knee and pushing back bone growth to better understand the forces that may cause repeated the whole scenario one more time, too: if a subject went up again. What nobody seemed to have thought about before, leg back: it would force the hip into an injurious position. “A bone to develop abnormally. through the routine standing up, Lewis would ask them to squat says Lewis, is the nonstanding leg’s position. And yet it has a big single leg squat with your leg behind you seems to work the “It’s exciting to think we don’t have to injure ourselves to and repeat. Lewis says the standing and band positions were impact on how the exercise works. quadriceps muscle more,” says Lewis. “A single leg squat with see a rehabilitation specialist,” says Dean Christopher A. Moore randomized in case one position affected the next. “If I stand on my right leg and hold my left leg out in front of your leg in the middle or out in front works your gluteals and of Lewis’ impact on the wider field. “This approach broadens The step distance was not randomized. As the subjects me, just to hold my leg out there, I’m going to tip my trunk back hamstrings more.” the appeal of Dr. Lewis’ work to many more people—young and moved through the room, they were told to step one floor tile a little bit, so I squat differently,” she says. “The second I put it old, injured and not injured.” Moore adds that the analytical at a time. “Some studies will do it on leg length and all these behind me, I lean forward more as I squat and I also drop my MORE THAN TREATMENT and mechanical approach taken by Lewis “requires the skills other parameters,” says Lewis. “We just used the floor tiles to hip a little bit more.” At Sargent, Lewis has the opportunity—albeit between of a counselor, a therapist, an engineer, a physiologist, and a be practical. In the clinic, you’re not going to sit there and put For example, if a clinician were treating someone with teaching courses (she also holds an assistant professor good bit of Dr. Emmett Brown,” ’s resourceful all these different side step lengths down on the floor when you femoroacetabular impingement, a common cause of hip position on BU’s Medical Campus) and directing a lab—to inventor. “She’s one of the rare scientists who has all of those

have floor tiles and you can say, ‘OK, step this far.’” osteoarthritis, they would want to avoid holding the air-bound AGUIRRE DAN study the efficacy of exercises and treatments many take for capabilities.” IS

16 InsideSARGENT | 2015–2016 | bu.edu/sargent bu.edu/sargent | 2015–2016 | InsideSARGENT 17 DISCOVERY Her researchwas partiallyfundedwithafive-year CentersforDis plans toperformaparticularactionatspecifictimeandplace. practice calledimplementationintentions, inwhichanindividual eating morefruitsandvegetables—Michele DeBiasseisstudying a between theirintentionsandadopting healthy habits—specifically, 18 through which DeBiasse couldassesstheirprogress. grapefruit.” Onemonthlater, they completed ashortsurvey waiting topickupmy childfromschool,thenIwilleathalf a 4 p.m., andIam onthelivingroomcouchwatching TV while the planinan“if-then”format, suchas:“Ifit’s between 3and and timeswhentheycoulddo so. Shethenasked them towrite the courseofamonth,whichinvolved noting specificplaces to eatoneadditionaldailyservingoffruitsorvegetables over SES. Inaphoneconversation, shehelpedthemcreateaplan test implementation intentionsexclusively with womenoflow ing tojoinherintervention study, whichshesays isthefirst to to stick withahealth plan. barriers, includingeconomics, won’t necessarily getsomeone make adifference, says DeBiasse.Buteven addressingahost of using government assistance couponsatfarmersmarkets—can lower costs—choosing cannedorfrozen foods, forexample,and economics. Showing peoplehow tobuyfruitsandvegetables at know forthem.Shebelieves onereasonis thesefoodsaregood aren’t eatingmany fruitsandvegetables, even thoughthey ers anddaughterswholive inpublichousing ingreaterBoston ducted withtheassistance ofSPH,DeBiassefoundthatmoth face highhurdlesinimproving theirdiets. Inastudy shecon is workingwithwomenoflow socioeconomicstatus (SES)who that promotes thehealthofBHAresidents. Committee, andBoston University SchoolofPublicHealth (SPH) (BHA), Boston PublicHealth Commission, thePHHCommunity Housing (PHH),acollaborationamongBoston Housing Authority ease ControlandPrevention grantforthe Partnership inHealth & W OF PLANS CHANGE

Inside DeBiasse invited someofthewomenlivinginpublic hous clinicalassistant DeBiasse, aSargent professor ofnutrition, SARGENT

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2015–2016 slip up setting andgetting agoal ingear, we leafy greens. Butsomehow, between carbs orthejunkfoodandeatmore e alldoit.W To helppeoplemake theleap

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. bu.edu/sargent e intend to ease up on the e intendtoeaseuponthe - - - - our NewYear’s resolutions. health. Andall of usmightlearnathingortwo aboutkeeping help individualsorgroupsoflow SEStoimprove theiroverall professionals nationwide wouldhave asimple,low-cost toolto pared tojust 38percentofthecontrolgroup. would exercise followed throughonce ormoreaweek,com participants whowrote aplanspecifyingwhenandwherethey of HealthPsychology, forexample,showed that91percentof their goals. One frequentlycitedstudy intheBritishJournal shown tosignificantly increasepeople’s successinreaching she’s ontherighttrack:implementationintentionshasbeen the intervention shows promise,existing research indicates the trackinstead.” work late,Iwillgetupanhourearlythenext day towalk at account forunexpectedcircumstances, suchas, “IfIhave to sions: youjust doit.You plansto canalsomake contingency tothetrack”—youthen Iwillgo don’t have tomake any deci if youmake aplan—“IfI’m homefromworkby sixo’clock, easier foryoutojust say, ‘Oh, forgetit!’”says DeBiasse.But for how long?” now towalk orwaitand untilafterdinner?WhereamIgoing asse. Whentheopportunityarises, youdebate,“Should Idothis the behavior automatic.Take walking forexercise, says DeBi todoit.”was going Second, aspecificif-thenplanhelpsmake more fruitsandvegetables] oractually plannedwithmehow I participants toldher, “Nobody’s ever asked me[abouteating thanavagueintention.DeBiasse saysthem reachagoal study gotaplan,whichismorelikelyFirst, tohelp itmeansthey’ve OUR INTENTIONS.—BYBUTTERS JULIE AND ALL OF US—FOLLOW THROUGH ON OF LOW SOCIOECONOMIC STATUS— DEBIASSE KNOWS CAN HELP WOMEN RESOLUTIONS? WHAT MICHELE WHY DO WE BREAK OUR HEALTH If theintervention works, says DeBiasse,publichealth While DeBiasseneedstofinishanalyzingthedataseeif “Having tothinkthroughallthesequestions makes it There aretwoprimaryreasonsthismethod shouldwork. thinks it could help useat healthier. reach their goals. Michele DeBiasse method proven to help people Implementation intentions isa I S - - -

DAN AGUIRRE IN THE WORLD

of Science is a highly engaging, interactive, and motivating them. One child asked a friend to “come over here and look at On Their environment,” she says. “Because the content of the exhibits the armadillo,” and another asked his teacher to join him in is so compelling to youth, they have a great desire to be at the looking at a shell. “That’s the kind of spontaneous interaction museum, and because they have an interest in the exhibits,” that happens at the museum that we don’t think would happen they’re more likely to share that interest with others. They’re in the classroom,” Cohn says. Behavior learning new things, and they are interacting socially—and At the end of each visit, the OT students reinforce the BEST spontaneously—with support from Sargent’s OT students. children’s goal-setting by pointing to specific examples of A TRIP TO THE SCIENCE MUSEUM HELPS YOUTH WITH AUTISM For the first two weeks of Cohn’s class in January, the OT their successful behavior. It’s important for the youth to students get to know the children in the BPS classroom setting. assess for themselves whether they met their goals because PRACTICE THEIR SOCIAL SKILLS | BY LARA EHRLICH Together, they develop social stories, booklets that outline “we’re trying to promote their perceived sense of competence the activities the children will participate in at the museum in their ability to be successful science learners and social and identify the behavior expected of them. For example, participants,” Cohn says. “When we get to the museum we will walk together to meet At the end of the program, the OT students and museum VERY SUMMER, the Museum of Science, Boston, Museum Teachers. Museum Teachers wear red coats and they staff also interview the teachers about how the visits benefit offers children’s programs on subjects like rockets, will help us learn about science.” They also set learning and their students, and how BEST reinforces their learning goals. dinosaurs, and electricity. The programs are popular social participation goals for their visit, such as “I will ask my According to teacher assessments before and after the 2014 with children on the autism spectrum, who may friends questions about themselves and their interests” and “I program, 9 of the 15 children demonstrated improvement in have an aptitude for science, technology, engineer- will share things with my partner.” This goal-setting process skills such as participating in group activities, sharing with ing, and math (STEM), and develop focused inter- is vital, says Cohn, because the children “are more intentional others, and demonstrating flexibility in unplanned situa- E ests in these areas. These children also have difficulty with social when they set specific goals, and we see better outcomes when tions. The children, too, reported improvement in their social interaction; at the start of a program, they would be more likely the goals are co-constructed or negotiated” between the OT skills and behaviors. to pull out a book during lunchtime, rather than eat with the students and the children. The OT students benefit as much as the youth. “It’s all other kids, says Annette Sawyer, director of the museum’s edu- The children’s enthusiasm underscores the success of the about the community,” Cohn says. Through the BEST pro- cation and enrichment programs. As the program progressed, program. They have expressed excitement with comments gram, the OT students “learn that some of our partners don’t however, Sawyer noticed that the children and their peers con- like “awesome” and “cool,” asked questions, and participated necessarily have to be medical practitioners in a hospital or nected through their shared interest in science. Sawyer set out in presentations. During the time provided for independent rehabilitation hospital. Our partners can be educators and to see if there was more the staff could do to create a supportive exploration, they often lingered at exhibits that interested exhibit designers and docents in museums.” IS learning environment for the children with autism. In 2009, she called Sargent for help. Ellen Cohn, a clinical professor of occupational therapy at Sargent, and her colleagues began working with Sawyer Children impacted by autism spectrum and her staff to make the museum more inclusive. In 2011, disorder may have an aptitude for the STEM fields, but find social interaction this collaboration expanded into the Buddies Exploring Sci- challenging. At the Museum of Science, ence Together (BEST) program, a partnership of Sargent, the Boston, they learn new things and museum, and Boston Public Schools (BPS) that serves children interact socially, with support from with autism. Each spring semester, the OT students from Sargent’s OT students. In 2014, 9 of Cohn’s Group Leadership Experience course co-lead a group of the 15 participants demonstrated 15 BPS students ages 9 to 16 improvement in their social skills. on weekly field trips to the museum. Now in its fourth year, the BEST program “flips the conversation about youth with autism” says The BEST program Cohn, who is also the direc- tor of Sargent’s Entry-Level “flips the conversation Doctorate in Occupational about youth with Therapy (OTD) Program. Typical interventions Ellen Cohn’s OT students autism.” for people with autism co-lead BPS students on weekly focus on addressing an field trips to the museum. —Ellen Cohn individual’s social deficits and on teaching social skills, such as making eye contact and conducting a reciprocal conversation. These lessons often take place in a classroom or clinic and are not easily trans- ferable to other environments and situations, says Cohn.

“We know it is helpful to teach in context, and the Museum VERNON DOUCETTE, RIGHT LEFT; BOSTON, OF SCIENCE, MUSEUM IMAGES (2); TMP BOSTON OF SCIENCE, MUSEUM IMAGES; TMP

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Since Dori Hutchinson problems, psychiatric and mental health problems like bipolar established Niteo in 2014, disorder, or a depressive disorder,” says Larry Kohn, the cen- the majority of participants have completed the program, ter’s director of development. These problems often worsen in enrolled in college courses, college because of substance abuse and other risky behaviors and secured at least and the stress that comes with having more independence and part-time jobs. FIGHTING FOR responsibility. Students who manage their illnesses with the help of doctors, therapists, and medication may still have dif- ficulty meeting the demands of higher education on their own. When Hutchinson spoke at a 2013 meeting of the National Alli- ance on Mental Illness in Boston, “about 80 parents lined up to tell me the story of their kids, saying, ‘My kid didn’t get any support to stay in school.’” This is where Niteo comes in. The program “uses edu- cation to nurture the idea that people can heal from their A FUTURE experiences with mental health challenges and move forward to live the kind of life they want,” says Hutchinson, director of services at the center. “Education gives people a valued role. They’re not patients, consumers, or clients—they’re students. And there’s a foundation of optimism and hopeful- ness to that.” NITEO PROGRAM GETS The 30-week program is divided into two semesters. Dur- IMPACT: NITEO PROGRAM ing the first, students come to the center on Commonwealth COLLEGE STUDENTS Avenue three times a week for classes in coping skills like WITH MENTAL HEALTH 10 out of 12 students mindfulness and stress tolerance, as well as academic skills like completed the first semester. writing and test preparation. The second semester focuses on individual coaching to help the students over their personal CONDITIONS BACK hurdles, whether it’s a practical task like organizing a schedule or getting to class on time, or more complex, such as over- IN CLASS coming the feeling of stigma. The program can be adjusted to address each student’s needs, says Niteo program coordinator Courtney Joly-Lowdermilk. BY JOEL BROWN Of these, 3 found employment and Students in the first two cohorts, who started in fall 2014 7 returned to plan to return to school and spring 2015, had nearly identical results. A dozen students school, and after a second semester. enrolled each time; 10 in each group completed the classes and 7 have already taken at least one college course. About half also secured at least part-time jobs. The program starts a third cohort in September 2015. Hutchinson and colleagues hope to secure funding to keep the program going and to share their practices with campuses around the country. At 23, Abe is a Niteo success story. An inpatient treatment program finally provided a diagnosis to explain his challenges: be* began hearing voices as a boy. When ment specializing in psychiatric rehabilitation. Many become “Education gives people a schizo-affective disorder. His psychiatrist steered him to the he started drinking and smoking pot as a socially isolated or marginalized, and a job, career, and fulfill- center, where he’s known as an enthusiastic participant, work- teenager, the voices got stronger, and he ment may seem out of reach. Many end up on disability. To valued role. They’re not ing with both a college coach and a writing coach, speaking up was briefly hospitalized for psychiatric help students before they slip that far, Hutchinson and her col- in discussions, and even organizing social events for the group. treatment. Despite ongoing therapy and leagues at the BU Center for Psychiatric Rehabilitation (CPR) patients, consumers, or He attends Alcoholics Anonymous meetings, has two jobs, and medication, things fell apart in college. started the Niteo program. (Niteo is Latin for “to thrive.”) has been admitted to a new college. “I’m taking a course online “IA was so far off track,” says Abe (who is not a BU student). Established in 2014 and funded by a $175,000 grant from the clients—they’re students. there, and I have a 95 average,” he says. “Niteo made it possible, “I was miserable. I was drinking a lot and having lapses in Sidney R. Baer, Jr. Foundation, the program provides recovery because the last time I went back to college I was like a deer in reality and bad symptoms.” He was eventually suspended services and support to help students with serious psychiatric And there’s a foundation the headlights.” by an administration he says failed him, and moved back in challenges return to school. The program is open to college This progress, he says, has convinced him “that if I stay with his parents. students who live in the Boston area or attend school here, of optimism and sober and treat my symptoms and work hard at this, I can make Most students who leave college as a result of mental including BU. a difference in my life. I sort of lost hope at one point, and Niteo health problems do not return, says Dori Hutchinson, a clini- College and mental illness can be a combustible mix. hopefulness to that.” is one of the things that brought it back.” IS cal associate professor in the occupational therapy depart- “There are kids who come to school with attention deficit *Name changed for privacy DAN AGUIRRE DAN —Dori Hutchinson

22 InsideSARGENT | 2015–2016 | bu.edu/sargent bu.edu/sargent | 2015–2016 | InsideSARGENT 23

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Inside PARKINSON’S IMPACT OF THE SOCIAL SARGENT National Institute ofNursingResearch. is fundedby agrantofmorethan$2million from the Tickle-Degnen ontheimpact of Parkinson’s. Theproject project runbyfacultymemberLinda former Sargent colleagues atTuftsUniversity, ispartofafive-year brainstorm toworkbest what isgoing forthem,” shesays. ties, wecandevelop atoolbox forclinicians, tohelpclients stages ofParkinson’s usetomaintaintheirsocialactivi by gatheringall ofthestrategies thatpeopleatdifferent tionships, andhow couplescope.“One ofmy hopesisthat SHE USEDTO PRIDEHERSELF learn how thedisease affectssocialparticipationandrela is studying people withParkinson’s andtheirspousesto clinical associateprofessorofoccupationaltherapy who focused onthephysical symptoms, says SueBerger, a roles totheirspouses, andcansuffer fromdepression. social toll.Sufferersdropactivities, relinquishlong-held worldwide—affects physicala movement, italsoexacts brain diseaseaffectinganestimated 7to10millionpeople communicating achore.WhenParkinson’s—an incurable the party, butherincreasinglystiff expressionshave made tired tofinishagame. Friends onceknewherasthelifeof drill. He usedtocrushopponentsonthecourt—now he’s too Today, becauseofhertremors, herspousehastowieldthe

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2015–2016 This research, which Berger is conducting with isconductingwith This research,whichBerger And yet muchoftheintervention forParkinson’s is

| bu.edu/sargent “ on being Ms. Fix It. onbeingMs. FixIt. well-being.—Sue Berger connected for health and ting out and staying socially size the importance of get Clinicians should empha - - It mightworkforyou.” —JB partners, “Thisiswhat’s beenworkingfor people. will bebetter equippedtotellpatientsandtheir care of thedisease.Withthatinformation,shesays, clinicians son’s gender, socialimpactvarieswithage, andthestage most energetic. help patientsplanactivitiesfortimeswhentheyare that still offer socialinteraction,forexample—and activities thataretoodemandingwitheasierones ago.” Clinicianscanthenofferadvice—replacing and“IdoitlessthanIdidsixmonths as “Idoitnow” to swimming, thatpatientssortintocategories, such ofpastimes,of cardsdepictingarange fromcooking with thehelpofatoolusedinTuftsstudy—a set the activitiesthatpeoplewithParkinson’s in engage becoming isolated,says Berger. Clinicianscanassess intheirfavorite engage pursuitsareatriskoflonger nected forhealthandwell-being.” People whocanno importance ofgetting outandstaying sociallycon forced theideathatcliniciansshouldemphasize“the pation over time.Her analysisofearlydatahasrein later evaluatehow Parkinson’s impactssocialpartici spouses), mostly fromgreaterBoston; thestudy will people withParkinson’s andtheircarepartners(often Berger hopesthestudyBerger willreveal whether Parkin Berger is analyzing data from interviews with isanalyzingdatafrominterviews Berger I S ” - -

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PHOTOGRAPHER excluded groups. storytelling, projects forsocially andself-advocacy program, Photovoice, usesphotography, digital habilitation tocommunity-based settings. Onesuch ranging frominpatientrehabilitationtoday 25 skills.tive andlanguage Since2011: with aniPad loadedwithappstohelpimprove cogni specialists, theprogramprovides eachparticipant suffering fromaphasia.Led by BUfacultyandclinical sional Intensive TreatmentProgramtoserve people CENTER IN 2011, SARGENT’S APHASIA RESOURCE INTENSIVE TREATMENT PROGRAM STUDENTS SARGENT’S OCCUPATIONAL THERAPY FIELDWORK the program ticipated in aphasia par people with meant to them. integration after their brain injury to learn about what community relationships with participants, ­—Intern Angela Viani (’17) “ EDUCATION OF ACLINICAL THE VALUE I had the opportunity to develop launched a rigorous four-week launchedarigorous interprofes - complete Level IFieldworkatsites 100 improvement nificant language demonstrated sig of participants ”

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50 fessional training received interpro- Sargent students - - Intensive Language Program,amonthlonginten Intensive Language health carelandscape,andmoreformalizededu IPP areincreasinglyimportantintheemerging (IPP) naturalpartsofourprograms. Both IPEand education (IPE)andinterprofessionalpractice students andourpatients. innovative patient-centeredapproachestoour cational andclinicalstructures arebringingthese SARGENT COLLEGE THE INTERDISCIPLINARY CULTURE OF (IPE) COMMITTEE INTERPROFESSIONAL EDUCATION LANGUAGE PROGRAM PRESCHOOL INTENSIVE Academic Speech, Language &Hearing Speech,Language Center.Academic The programishosted by theBoston University intervention. cutting-edge approachestolanguage pathologystudents language develop expertisein disorders.language Throughthiswork,speech- and grouptherapy tofour- and five-year-olds with sive intervention programofferingdailyindividual IN 2015, SARGENT LAUNCHED training ­ ­intervention approaches and parent and the specific ­ the intensive nature of the ­ language &hearing sciences ­—Michelle Mentis, clinical professor of speech, “ my client. the end was the most beneficial to comfort zone asastudent, but in sometimes felt abit out of my of reaching out to others, which program, Ilearned the importance ­— “ Athina Kalemos (’15) The program isunique because of Throughout the course of the

sessions bu.edu/sargent ” makes interprofessional combination of . ”

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25 Grant Awards

PRINCIPAL TITLE AGENCY/FOUNDATION FUNDS YEAR OF TOTAL INVESTIGATOR OF PROJECT AWARDED AWARD AWARD 2014–2015

Grant Awards Marianne Farkas Toolkit of Recovery Promoting NIDILRR** $199,869 3 of 3 $599,504 Competencies for Mental Health Rehabilitation Providers Marianne Farkas and E. Sally Improved Employment Outcomes for US Department of $848,218 5 of 5 $4,245,042 Rogers Individuals with Psychiatric Disabilities Education BU SARGENT COLLEGE’S FACULTY RECEIVED $13,052,538 IN RESEARCH FUNDING IN 2014–2015. HERE IS A LIST OF Miguel García-Cabezas, research Circuits and Molecular Features of Brain & Behavior Research $30,000 1 of 2 $65,000 OUR PROJECTS AND THE AGENCIES AND FOUNDATIONS associate Anterior Cingulate Areas and Depression Foundation

SUPPORTING THEM. Simone Gill, assistant professor of Multicenter Career Development NIH/NICHHD $135,000 2 of 2 $270,000 occupational therapy Program for Physical and Occupational Therapy Massive Weight Loss and Its Effects on NIH/NIAMS $83,561 1 of 3 $270,438 Postural Stability and Fall Risks

Mahasweta Girgenrath, assistant Modulation of Inflammation and Fibrosis MDA $119,149 3 of 3 $357,465 PRINCIPAL TITLE AGENCY/FOUNDATION FUNDS YEAR OF TOTAL professor of health sciences in the Context of Regeneration in MDC1A INVESTIGATOR OF PROJECT AWARDED AWARD AWARD 2014–2015 Inhibition of Angiotensin II Signaling in Cure CMD $50,000 2 of 2 $100,000 Congenital Muscular Dystrophy Type 1A (MDC1A) Sudha Arunachalam, assistant A Non-Interactive Method for Teaching Autism Speaks $58,900 2 of 2 $118,886 professor of speech, language & Noun and Verb Meanings to Young Evaluating Efficacy of ANG(1-7) in Tarix Orphan, LLC $25,000 1 of 1 $25,000 hearing sciences Children with ASD Improving Survivability in FYW Mice Toddlers’ Representations of Verbs: Northwestern University $57,706 2 of 2 $119,847 Effects of Delay and Sleep on Verb Jennifer Gottlieb, research assistant Internet-Based CBT for Schizophrenia: NARSAD $0 1 of 1 $21,891 Meaning professor, BU Center for Psychiatric A Pilot RCT Computer-Based Program Rehabilitation for Auditory Hallucinations Mechanisms Underlying Word Learning NIH/NIDCD $172,195 2 of 4 $688,018 in Children with ASD: Non-Social Improving Quality and Reducing CMMI $81,326 3 of 3 $409,022 Learning and Memory Consolidation Cost in Schizophrenia Care and New Technologies and New Personnel Individual Differences in Toddlers’ Language Learning $10,000 1 of 1 $10,000 Abilities to Learn New Verbs From Their Frank Guenther, professor of Neural Modeling and Imaging of Speech NIH/NIDCD $353,515 4 of 5 $1,862,227 Linguistic Context speech, language & hearing sciences Helen Barbas, professor of health Organization of Prefrontal Feedback NIMH $438,124 5 of 5 $2,260,464 sciences Circuits Sequencing and Initiation in Speech NIH/NIDCD $344,384 4 of 5 $1,834,729 Production Prefrontal Anatomic Pathways in NINDS $567,217 1 of 1 $567,217 Executive Control Minimally Verbal ASD: From Basic NIH/NIDCD $347,133 2 of 4 $1,982,833 Mechanisms to Innovative Interventions Prefrontal Anatomic Pathways in NINDS $374,799 5 of 5 $1,990,887 Executive Control Kenneth G. Holt, associate Smart Exoskeleton Suit­­—Biomechanically Wyss Institute for $116,140 2 of 2 $116,140 professor of physical therapy Synergistic Body Support and Biologically Inspired Helen Barbas and Claire Timbie, Circuitry of Emotion: Integration in NIH $41,340 5 of 5 $182,112 & athletic training Protection System Engineering—Subcontract predoctoral student Orbitofrontal Cortex Smart Exoskeleton Suit­­—Biomechanically Wyss Institute for $54,856 1 of 1 $54,856 Shelley Brown, clinical assistant Boston University Health Science Association of American $10,000 2 of 2 $10,000 Synergistic Body Support and Biologically Inspired professor of health sciences Program: Developing Global Citizens Colleges and Universities Protection System Engineering—Subcontract through Civic Engagement in Public Health Biologically Inspired Soft Smart Exosuit Wyss Institute for $67,800 1 of 1 $175,888* for Injury Prevention and Performance Biologically Inspired Augmentation Engineering—Subcontract Terry Ellis, assistant professor of Telemedicine Intervention to Improve Department of Veterans $81,835 1 of 1 $81,835 physical therapy & athletic training Physical Function in Persons with Affairs (VA) Parkinson Disease Norman Hursh, research associate The City Connects Model of Student Boston College $22,871 4 of 4 $162,051 professor of occupational therapy Support: Building a K–12 Student Mobile Health Technology to Promote American Parkinson $50,000 2 of 2 $100,000 Support Practice and Process Physical Activity in Persons with PD Disease Association, Inc. Karen Jacobs, clinical professor of Project CAREER: Development of a Kent State University/ $82,885 2 of 5 $407,210* CPS: TTP Option: Synergy: Human Wyss Institute for $74,039 1 of 3 $328,803* occupational therapy Multidisciplinary Demonstration to NIDILRR** Machine Interaction with Mobility Biologically Inspired Support the Transition of Students Enhancing Soft Exosuits Engineering—NSF with Traumatic Brain Injuries Subcontract from Postsecondary Education to Maintaining Physical Independence in Spaulding Rehabilitation $60,013 1 of 3 $170,807* Employment Older Adults Hospital Rx Foundation Subcontract Susan Kandarian, professor of The Molecular Basis of Muscle Wasting NIH/NIAMS $360,958 4 of 5 $1,815,430 health sciences in Cancer Cachexia Marianne Farkas, clinical professor Bringing Recovery Supports to Scale SAMHSA $35,000 4 of 5 $708,521 of occupational therapy and Technical Assistance Center Strategy Julie Keysor, associate professor of ENACT HHS/DOE $799,991 4 of 5 $3,999,923 director of training & international physical therapy & athletic training services, BU Center for Psychiatric Rehabilitation, and E. Sally Rogers, New Investigator Workshop on NIH/NIAMS $15,000 1 of 1 $15,000 research professor of occupational Advancing Arthritis Research therapy and director of research, BU Center for Psychiatric Osteoarthritis Action Alliance University of North $43,786 1 of 1 $43,786 Rehabilitation Carolina/Arthritis Foundation

26 InsideSARGENT | 2015–2016 | bu.edu/sargent bu.edu/sargent | 2015–2016 | InsideSARGENT 27 Grant Awards Grant Awards

PRINCIPAL TITLE AGENCY/FOUNDATION FUNDS YEAR OF TOTAL PRINCIPAL TITLE AGENCY/FOUNDATION FUNDS YEAR OF TOTAL INVESTIGATOR OF PROJECT AWARDED AWARD AWARD INVESTIGATOR OF PROJECT AWARDED AWARD AWARD 2014–2015 2014–2015

Gerald Kidd, professor of speech, Spatial Hearing, Attention, and US Air Force $233,739 3 of 3 $685,945 Zlatka Russinova, research Patient Navigation and Financial ACS $9,782 1 of 1 $9,782 language & hearing sciences Informational Masking in Speech associate professor of occupational Incentives to Promote Smoking Identification therapy and senior research Cessation specialist, BU Center for Psychiatric Central Factors in Auditory Masking NIDCD $533,202 4 of 5 $2,694,821 Rehabilitation Top Down Control of Selective NIH/NIDCD $535,871 2 of 5 $2,750,773 Enhancing Community Living and NIDILRR** $499,907 1 of 1 $2,499,724 Amplification Participation of Individuals with Psychiatric Disabilities Gerald Kidd and H. Steven Core Center Grant—Sound Field NIDCD $212,929 5 of 5 $1,208,700 Colburn, professor of biomedical Laboratory (Core 1) Recovery 4 Us—Development of NIDILRR** $199,895 1 of 1 $599,855 engineering a Photovoice-Based Social Media Intervention to Enhance Recovery Swathi Kiran, professor of speech, Theoretically Based Treatment for NIH/NIDCD $0 5 of 5 $2,369,071 Peer-Led Photovoice for Overcoming NIH $569,776 1 of 1 $2,158,965 language & hearing sciences Sentence Comprehension Deficits in Prejudice and Enhancing Community Aphasia Integration The Neurobiology of Recovery in Subaward—Northwestern $398,289 3 of 5 $1,299,549* Advanced Research Training Program in ED $149,968 2 of 5 $749,806 Aphasia: Natural History and Treatment- University Employment and Vocational Rehab Induced Recovery

Elliot Lee Saltzman, associate RI: Medium: Collaborative Research: NSF $52,627 2 of 4 $52,627 Jessica Kramer, assistant professor Multicenter Career Development NIH/NICHHD $135,000 2 of 2 $270,000 professor of physical therapy & Multilingual Gestural Models for Robust of occupational therapy Program for Physical and Occupational athletic training Language-Independent Speech Therapy Recognition Evaluation of Project TEAM (Teens NIDILRR** $199,657 3 of 3 $597,509 Modeling the Behavioral Dynamics of NIH/NIGMS—Subaward, $24,900 3 of 5 $124,500* Making Environmental and Activity Social Coordination and Joint Action University of Cincinnati Modifications)—Effectiveness Social Validity and Feasibility Joshua Stefanik, research assistant Effect of Massive Weight Loss on Arthritis Foundation $50,000 3 of 3 $150,000 professor of physical therapy & Patellofemoral Joint Structure and Pain Susan Langmore, clinical professor Non-Invasive Brain Stimulation for Beth Israel Deaconess $115,990 2 of 5 $476,591* athletic training of speech, language & hearing Swallowing Recovery After Dysphagic Medical Center sciences Stroke Identifying Cases of PFJ OA & Their Hip RRF/ACR $124,998 1 of 3 $374,998 Impairments

Cara L. Lewis, assistant professor of Effect of Femoroacetabular Impingement NIH/NIAMS $130,680 2 of 5 $653,400 physical therapy & athletic training (FAI) on Hip Motion in Young Adults Cara E. Stepp, assistant professor Career: Enabling Enhanced NSF $110,143 1 of 5 $537,538 of speech, language & hearing Communication through Human- Sex-Specific Movement Pattern NIH/NIAMS $209,945 2 of 2 $405,158 sciences Machine-Interfaces Differences in Young Adults With and Without Hip Pain Automation of Relative Fundamental NIH/NIDCD $163,700 2 of 3 $480,927 Frequency Estimation SBIR Phase II: Compliant Nonlinear Adicep Technologies $42,768 2 of 2 $70,000 Quasi-Passive Orthotic Joint Development of an Griffin Laboratories, Inc. $26,110 2 of 2 $49,615 Electromyographically Controlled (NIH/NIDCD) Electrolarynx (EMG-EL) Voice Prosthesis Susan McGurk, associate professor Neuroscience-Guided Remediation of NIH $0 2 of 2 $47,733 of occupational therapy and Cognitive Deficits in Schizophrenia Videogame-Based Speech Rehabilitation Deborah Munroe Noonan $80,000 1 of 1 $80,000 senior researcher, BU Center for for Children with Hearing Loss Memorial Fund Psychiatric Rehabilitation A Dismantling Study of Cognitive NIMH $522,538 4 of 5 $2,771,031 Gloria S. Waters, professor of Assessment of Comprehension Skills in ED $0 5 of 5 $1,597,065 Remediation for Supported Employment speech, language & hearing Older Struggling Readers sciences

Kim Mueser, executive director, Treating Co-Occurring Substance NIH $18,827 1 of 3 $56,481 Gloria S. Waters and William Evans, Attention and Executive Control During NIH/NIDCD $33,986 2 of 2 $70,476 BU Center for Psychiatric Use and Mental Disorders Among Jail doctoral student Lexical Processing in Aphasia (NRSA) Rehabilitation, and professor of Inmates occupational therapy Stacey Zawacki, director, BU Statewide Intervention to Reduce Early NIH/NIMH $18,133 1 of 1 $18,133 Recovery After an Initial Schizophrenia NIMH $57,536 5 of 5 $143,267 Sargent Choice Nutrition Center Mortality in Persons with Mental Illness Episode (RAISE) Enhancing Assertive Community NIH/NIMH $42,532 4 of 5 $192,913 Basilis Zikopoulos, research Organization of Excitatory and Inhibitory NIH/NIMH $395,236 2 of 5 $2,018,222 Treatment with CBT and SST for assistant professor of health Prefrontal Circuits in Children with Schizophrenia sciences Autism Effectiveness of Psychosocial Treatment NIH $18,827 2 of 3 $56,481 for Inpatients with Psychosis Total $13,052,538 $58,521,470

Development and Randomized NIDILRR** $14,814 2 of 3 $37,035 *Total anticipated subcontract Controlled Trial of a Mobile System for Self Management of Schizophrenia **Formerly NIDRR

E. Sally Rogers, research professor Improved Employment Outcomes for NIDILRR** $874,965 1 of 5 $4,374,848 of occupational therapy, and Individuals with Psychiatric Disabilities Marianne Farkas, clinical professor of occupational therapy

28 InsideSARGENT | 2015–2016 | bu.edu/sargent bu.edu/sargent | 2015–2016 | InsideSARGENT 29 Faculty in Print Faculty in Print

OUR FACULTY’S RESEARCH REACHES AUDIENCES ACROSS THE GLOBE. HERE’S A SELECTION OF PUBLICATIONS AND ARTICLES WRITTEN BY BU SARGENT COLLEGE FACULTY DURING 2014–2015.

Arunachalam, S., and Waxman, S. R. Starkey, C. A., and Brown, S. D. (2015). Heislein, D. M. Total hip arthroplasty during a manualized self-advocacy inter- (2015). Let’s see a boy and a balloon: argu- Examination and Diagnosis of Orthopedic clinical summary. PTNow.org, American vention for transition-age youth. OTJR: ment labels and syntactic frame in verb Injuries, 4 (Philadelphia: F. A. Davis). Physical Therapy Association. Occupation, Participation and Health, 35, learning. Language Acquisition: A Journal (1), 23–33. Cohn, E. S., Coster, W. J., and Kramer, Asbeck, A., DeRossi, M. M., Holt, K. G., of Developmental Linguistics, 22, 117–131. J. M. (2014). Facilitated learning model to and Walsh, C. J. (2015). A biologically Langmore, S. E., and Pisegna, J. M. Bandini, L., Danielson, M., Esposito, teach habits of evidence-based reasoning inspired soft exosuit for walking assis- (2015). Efficacy of exercises to rehabilitate L. E., Foley, J. T., Fox, M. H., Frey, G. C., across an integrated master of science in tance. International Journal of Robotics dysphagia: a critique of the literature. Fleming, R. K., Krahn, G., Must, A., Por- occupational therapy curriculum. Ameri- Research. 1–19. International Journal of Speech-Language retta, D. L., Rodgers, A. B., Stanish, H., Urv, can Journal of Occupational Therapy, 68, Pathology. 17(3):222–9. Hoover, E. L., Caplan, D., Waters, G., and T., Vogel, L. C., and Humphries, K. (2015). S73–S82. Budson, A. (2015). Effects of impairment- , Foch, E., Luko, M. M., Obesity in children with developmental Lewis, C. L. Whited, M. C., Schneider, K. L., Appel- based individual and socially oriented Loverro, K. L., and Khuu, A. (2015). and/or physical disabilities. Disability hans, B. M., Ma, Y., Waring, M. E., DeBi- group therapies on verb production in Differences in lower extremity and and Health Journal, Epub. (3):309–16. asse, M. A., Busch, A. M., Oleski, J. L., aphasia. Aphasiology, 29(7), 781–798. trunk kinematics between single leg doi: 10.1016/j.dhjo.2015.04.005. PMID: Merriam, P. A., Olendzki, B. C., Crawford, squat and step down tasks. PLOS ONE. 26058685. Cason, J., and Jacobs, K. (2014). Snap- S. L., Ockene, I. S., Lemon, S. C., and 10(5):e0126258. doi: 10.1371/journal. shots of current telehealth applications in Barbas, H., and Zikopoulos, B. (2014). Pagoto, S. L. (2014). Severity of depressive pone.012625. occupational therapy. OT Practice, 7–12. Toward patient-specific targeting and symptoms and accuracy of dietary report- Caron, R., , , parameter setting of deep brain stimula- ing among obese women with major Cornwell, E. W., Mirbod, A., Wu, C. L., Lewis, C. L. Saltzman, E. Wagenaar, R.C., and Holt, K.G. (2015). tion for relief of depression. Commentary. depressive disorder seeking weight loss Kandarian, S. C., and Jackman, R. W. Musculoskeletal stiffness changes linearly Biological Psychiatry, 76: 914–916. treatment. PLOS ONE. 9(2):e90361. doi: (2014). C26 cancer-induced muscle wast- in response to increasing load during 10.1371/journal.pone.0090361. PMID: ing is IKKß-dependent and NF-kappaB- Berger, S., Aravich, D., Dastur, N., Fried- walking gait. Journal of Biomechanics. 24587338. independent. PLOS ONE. 9(1):e87776. man, C., and Son, C. (2014). Changing the 48:1165–1171. doi: 10.1371/journal.pone.0087776. PMID: trajectory of stroke recovery through Cavanaugh, J. T., Ellis, T. D., Earhart, G. 24489962. , and Halloran, T. (2015). interprofessional care. OT Practice, 19(21), M., Ford, M. P., Foreman, K. B., and Dibble, Lowenstein, N. Case studies through the health care con- 7–12. L. E. (2015). Toward understanding ambu- Kidd, G. Jr., Mason, C. R., and Best, V. tinuum: a workbook for the occupational latory activity decline in Parkinson dis- (2014). The role of syntax in maintaining Bohland, J. W., Myers, E. M., and Kim, E. therapy student (2nd ed). (Thorofare, N.J.: ease. Physical Therapy. PMID: 25858971. the integrity of streams of speech. Journal (2014). An informatics approach to inte- Slack, Incorporated). of the Acoustical Society of America, 135, grating genetic and neurological data in García-Cabezas, M. Á., Barbas, H. 766–777. , Christie, R. E., and speech and language neuroscience. Neuro- (2014). Area 4 has layer IV in adult pri- Marinko, L. N. Lewis, C. L. (2015). Successful reha- informatics. 12(1):39–62. doi: 10.1007/ mates. European Journal of Neuroscience, Kiran, S., Meier, E. L., Kapse, K. J., and bilitation of a young adult with total hip s12021-013-9201-6. PMID: 23949335. Epub. (11):1824–34. doi: 10.1111/ejn.12585. Glynn, P. A. (2015). Changes in task-based arthroplasty a decade after a girdlestone PMID: 24735460. effective connectivity in language net- Brown, L. (2015). Examination, diagno- procedure: a case report, PM&R. doi: works following rehabilitation in post- sis, exercise intervention and outcome for Gill, S. V. (2015). The impact of weight 10.1016/j.pmrj.2015.04.002. stroke patients with aphasia. Frontiers in individuals with motor control and motor classification on safety: timing steps to Human Neuroscience, 9:316. Gao, Y. Z., Saphirstein, R. J., Yamin, R., function disorders. Clinical Exercise adapt to external constraints. Journal of Suki, B., and Morgan, K. G. (2014). Aging Pathophysiology for Physical Therapy Musculoskeletal and Neuronal Interac- Kramer, J. (2015). Identifying and impairs smooth muscle-mediated regula- (Thorofare, N. J.: Slack, Incorporated). tions, 15, 103–108. evaluating the therapeutic strategies used

30 InsideSARGENT | 2015–2016 | bu.edu/sargent 32

Inside Talker identificationacrosssource man, R.E.,andWong, P. C. M.(2014). Perrachione, T. K., Health, 35, 169–177. Research: Occupation,Participation, & tions. ity study: objectives andguidingques The distinctive featuresofafeasibil Orsmond, G. I.,andCohn,E.S. (2015). books Online),1–46. University Press. Published OxfordHand Barlow, Ed.),476–510. (NewYork: Oxford Clinical Psychology: UpdatedEdition(D.H. Schizophrenia. Mueser, K.T., andDuva,S. M. (2014). heart.00392.2014. PMID:25128168. ogy. 307(8):H1252–61.doi:10.1152/ajp Physiology: HeartandCirculatory Physiol absorption function?AmericanJournal of tion ofaorticstiffness: adefectinshock Faculty inPrint continued from previous page SARGENT Occupational Therapy Journal of Now, we’re hosting thediscussion. We’ve beendoing theresearch. ATHLETIC TRAINING| NUTRITION | SPEECH, LANGUAGE &HEARINGSCIENCES OCCUPATIONAL THERAPY | The full conference is archived online. communication neuroscience, obesity, concussion management,traumatic brain injury, andchilddevelopment. In September 2015, we hosted afree, informative conference dealingwithtoday’s health issues. Topics included Sargent College isaleaderinresearch, scholarship, education, andclinicalpractice inhealthandrehabilitation. @BUSargent BUSargent

The Oxford Handbookof |

2015–2016 Stepp, C. E.,Hill HUMANPHYSIOLOGY |

| bu.edu/sargent REHABILITATION SCIENCES - - PHYSICAL THERAPY - - - - Check out the presentations and panel discussions at healthmatters.bu.edu. mechanisms: experimentswithlaryn Hearing Research. tion. with aerodynamicsandlistener percep relationships fundamental frequency: monitoring ofvocal effortwithrelative L., andStepp, C. E.(2015). Individual Lien, Y. S., Michener, C. M.,Eadie,T. PMID: 26067683. 5(2):324–40. doi:10.3390/bs5020324. school. environmental intervention inmiddle purchase behavior duringayear-long mographic predictorsofschoollunch (2015). Bodymassindexandsociode Cozier, Y. C., andQuatromoni,P. A. Greece, J. A.,Kratze,DeJong, W., 57, 1651–1665. Speech, Language,andHearingResearch, andelectrolarynxspeech.Journal of geal HEALTH SCIENCE Journal ofSpeech,Language,and Behavioral Sciences(Basel).

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- - a t ters H learning. correlates ofspeechmotor sequence and Segawa, J. A.,Tourville, J. A. , Beal,D. S., 311(7):700–8. doi:10.1001/jama.2014.469.311(7):700–8. ture: arandomizedclinicaltrial.JAMA. following rehabilitationafterhipfrac exercise programonfunctionalrecovery Jette, A.M.(2014). Effectofahome-based P., Giorgetti, M.,Holt, N., Goehring,L.,and Heislein, D. M.,Mustafa, J., Pardasaney, Heeren, T., Goodyear, C., Zawacki, S., Latham, N. K.,Harris, B. A.,Bean,J. F., chology, 69, 136–155. Canadian Journal ofExperimental Psy of syntactic anddiscourseambiguities. (2015). Working memoryandtherevision Michaud, J., Guarino, A.,andWaters, G. Evans, W. S., Caplan,D., Ostrowski, A., ence, 27, 819–831. healthmatters.bu.edu ealth Guenther, F. H.(2015). Theneural Journal ofCognitive Neurosci A VIRTUAL CONFERENCE

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KALMAN ZABARSKY BU Sargent College environment fosters thevalues, effective communication, the needsoffuture healthprofessionals. Our learning continuously improves itsdegree programstomeet College care needsbecomemorecomplex, BUSargent health andrehabilitationincreases andsociety’s health leadership formorethan130 years. As knowledge about hasbeendefininghealthcare College Sciences: Sargent Boston ofHealth University College &Rehabilitation WHO WEARE

• • • New Programs • • • Special Programs PathologySpeech-Language &HearingSpeech, Language Sciences Rehabilitation Sciences Physical Therapy Occupational Therapy Nutrition Human Physiology (Pre-Med) Health Science Behavior &Health Athletic Training Programs of Study ABOUT US students Number offull-time STUDENTS Average GRE Average SAT CLINICAL SITES ALUMNI Part-time Full-time 69 FACULTY

     CombinedBSandMPHinPublicHealth Human Physiology and DoctorofPhysical Therapy ­Physical Therapy (newin2015) Fellowship inOrthopaedicManual Therapy (newin 2016) Entry-Level DoctorofOccupational (new in2016) Master ofScience inAthletic Training Combined BSandMSin Combined BSinHealth Studies

More than UNDERGRADUATE

16,550 and 3countries 1,228 1943 in 1,300 inall50states n/a 60 87 countries Percentage of BU Sargent College studentsPercentage College inentry-level ofBUSargent Board Exam National Certification Passing Rates •  •  •  PathologySpeech-Language Physical Therapy Occupational Therapy Nutrition (data averagedover thepast threeyears): graduate programswhopassedtheexamfirst time U.S. News &World Rankings ReportBest GraduateSchool GRADUATE  Physical TherapyProgramranked number16outof201 programs 156 programs Occupational TherapyProgramranked number2outof in thetop8percenttheirrespective fields: programstracked bySargent U.S. News &World Reportallrank Our graduateprogramsareofficiallyamongthenation’s best— of 250programs PathologySpeech-Language Programranked number21out 394 n/a 312

of servicestogreater Boston. outpatient rehabilitation centersthatoffer awiderange facilities acrossthecountry. alsooperates TheCollege internships areavailable atmorethan 1,300healthcare program withsubstantive clinical experience.Clinical fieldwork component,providing students inevery degree professionals. Ourcurriculumalsoincludesanimportant and clinicalskillsthatdistinguish outstanding health 100% 100% 100% 99%

At aGlance

NONPROFIT US POSTAGE PAID BOSTON MA PERMIT NO. 1839

14 Get in Touch To visit BU Sargent College or learn more about our academic programs, research, and clinical practice, please contact us:

Email: [email protected] 6 Phone: 617-353-2713 Mail:  Boston University College of Health & Rehabilitation Sciences: Sargent College 635 Commonwealth Avenue 10 Boston, Massachusetts 02215 bu.edu/sargent PHOTOGRAPHER

0915 4 InsideSARGENT | 2015–2016 | bu.edu/sargent