DOCSLIB.ORG

Područje Biomedicine I Zdravstva Farmaceutsko-Biokemijski Fakultet

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Područje Biomedicine I Zdravstva Farmaceutsko-Biokemijski Fakultet POPIS VALJANO PRIJAVLJENIH RADOVA ZA AK. GOD. 2014./2015. PODRUČJE BIOMEDICINE I ZDRAVSTVA FARMACEUTSKO-BIOKEMIJSKI FAKULTET 1. Ivan Sušanj i Matija Salopek Ispitivanje mehanizma toksičnosti vodenog ekstrakta kore obične krkavine (Frangula alnus Mill.) i emodina na stanicama ljudske krvi Kora obične krkavine, Frangula alnus Mill. (sin. Rhamnus frangula L.) priznata je kao laksativ. U biljnim ljekarnama se mogu nabaviti preparati na bazi kore obične krkavine, a ljekovito djelovanje kore obične krkavine odobreno je i od strane Europskog parlamenta kao biljni proizvod s „dobro ustanovljenom medicinskom upotrebom“ za liječenje opstipacije. Laksativno svojstvo kore obične krkavine pripisano je njenom sekundarnom metabolitu - emodinu. Na sredstvima na bazi kore obične krkavine naznačeno je da su namijenjeni samo za kratkotrajnu upotrebu. Naime, poznat je niz negativnih učinaka preparata na bazi kore obične krkavine – od gubitka kalija, nadraženosti crijeva do pigmentacije crijeva, a prijavljeni su i slučajevi razvoja karcinoma. Stoga je cilj ovoga istraživanja bio ispitati toksične učinke ekstrakta kore obične krkavine na stanicama ljudske krvi te utvrditi ulogu oksidacijskog stresa kao mogućeg mehanizma toksičnosti, u svrhu utvrđivanja mogućeg štetnog učinka ovoga preparata na ljudsko zdravlje. Kako bi se sa sigurnošću moglo pripisati toksične učinke kore obične krkavine emodinu, u istraživanje je uključen i emodin. Istraživanje je provedeno na ljudskoj krvi koja je tretirana ili vodenim ekstraktom kore obične krkavine (u koncentracijskom rasponu od 0 do 1750 μg/mL) ili emodinom (u koncentracijskom rasponu od 0 do 200 μg/mL) kroz 24 sata. Nakon tretmana u izoliranim mononuklearnim stanicama diferencijalnim bojanjem određena je citotoksičnost, komet testom oštećenje DNA, a razina oksidacijskog stresa određena je mjerenjem reaktivnih kisikovih vrsta (ROS) i glutationa (GSH). Rezultati su pokazali da je vodeni ekstrakt kore obične krkavine toksičan za ljudske stanice krvi već pri koncentraciji od 500 μg/mL, a emodin pri koncentraciji od 150 μg/mL. Te su koncentracije bile i genotoksične, odnosno uzrokovale su značajno oštećenje DNA stanica ljudske krvi. Praćenje razine oksidacijskog stresa pokazalo je da i vodeni ekstrakt kore obične krkavine i emodin pri koncentracijama koje nisu bile ni citotoksične ni genotoksične povećavaju stvaranje ROS što ukazuje na to da je oksidacijski stres mehanizam citotoksičnosti i genotoksičnosti kako kore obične krkavine tako i emodina. Dobiveni rezultati potvrđuju da je emodin taj koji pridonosi njenom toksičnom učinku. Obična krkavina i emodin toksični su za stanice ljudske krvi te stoga preparate na bazi obične krkavine ili one koji sadrže emodin treba koristiti oprezno. Bark of Frangula alnus Mill. (syn. Rhamnus frangula L.) in traditional folk medicine is used as a mild laxative. Medicines based on F. alnus bark are easily obtainable, and according to the EU parliament are considered as medicinal products with “well-established medicinal use”. Laxative properties of F. alnus bark are attributed to its main anthraquinone derivate emodin. It is suggested that medicines based on bark of F. alnus should only be considered for short term use. There are a number of known side-effects of medicinal preparation based on F. alnus. bark ranging from potassium deficiency, bowel irritability to the risk of developing carcinoma. Therefore, the goal of this study was to establish toxic effects of F. alnus bark by assessing toxicity of extract of F. alnus bark as well as of emodin and to determine whether oxidative stress is a possible mechanism of their toxicity. Obtained results will possibly help clarify the mechanisms of side-effects of medicinal preparations based on F. alnus bark on human health. The experiments were conducted on human blood samples treated with either water extracts of F. alnus bark (concentrations ranging from 0 to 1750 μg/mL) or emodin (concentrations ranging from 0 to 200 μg/mL) for 24 hours. After treatment, in isolated mononuclear cells parameters of cytotoxicity, genotoxicity and oxidative stress were determined. Oxidative stress was determined by assessing the level of reactive oxygen species (ROS) and glutathione (GSH) in the cell. The water extract of F. alnus bark was cytotoxic to the mononuclear blood cells at concentration of 500 μg/mL and emodin at 150 μg/mL. These concentrations were also genotoxic, meaning they caused significant DNA damage to the mononuclear blood cells. The F. alnus bark and emodin both induced an increase in ROS level in the concentrations that were neither cytotoxic nor genotoxic, pointing to the fact that oxidative stress is the mechanism of their cytotoxicity and genotoxicity. Results of this study indicate that emodin, the main anthraquinone derivative in F. alnus bark contributes greatly to toxic effects of F. alnus bark and that bark of F. alnus and emodin are both toxic to human blood cells. Therefore, pharmaceuticals based on F. alnus bark or emodin should be used with caution. Obrazloženje mentora, Ivan Sušanj, Farmaceutsko-biokemijski fakultet Natječaj za dodjelu Rektorove nagrade za ak. god. 2014/2015. Prosudbenom povjerenstvu PREDMET: Obrazloženje mentora o udovoljavanju kriterijima izvrsnosti i preporuka Ivan Sušanj i Matija Salopek studenti su druge godine studija Farmacije na Farmaceutsko-biokemijskom fakultetu Sveučilišta u Zagrebu. Pod mojim vodstvom izradili su rad pod naslovom „Ispitivanje mehanizma toksičnosti vodenog ekstrakta kore obične krkavine (Frangula alnus Mill.) i emodina na stanicama ljudske krvi“ te ga prijavili na natječaj za Rektorovu nagradu u akademskoj godini 2014/2015. Tema rada vrlo je zanimljiva i aktualna ne samo s farmaceutskog već i s opće-zdravstvenog gledišta. Preparati na bazi kore obične krkavine i emodina često se koriste kao laksativna sredstva, iako toksikološki profil takvih preparata nije u potpunosti ispitan. Stoga je u ovome radu sistematski pristupljeno ispitivanju toksičnih učinaka i mehanizama toksičnosti kore obične krkavine i emodina, a s ciljem da se utvrde mogući toksični učinci ovog biljnog preparata na ljudsko zdravlje. Predloženi rad sastoji se od 49 stranica, 19 slika i 44 literaturna navoda. Ovo istraživanje nastavlja se na dosadašnja istraživanja projekata koji su u prethodnom razdoblju financirani od Ministarstva znanosti, obrazovanja i sporta: Mutageni i antimutageni u ekogenetičkim istraživanjima (022-0222148-2125) i Mikromorfološka i kemotaksonomska istraživanja nekih vrsta porodica Lamiaceae (006-0000000-3178). Važno je napomenuti da je ovo istraživanje povezalo istraživače sa znanstvenih i znanstveno-nastavnih institucija u Zagrebu, odnosno s Instituta za medicinska istraživanja i medicinu rada i s Farmaceutsko-biokemijskog fakulteta Sveučilišta u Zagrebu. Iako su Ivan Sušanj i Matija Salopek student tek druge godine pokazali su veliki interes za usvajanje novih znanja i vještina. Aktivno su sudjelovali u svakoj fazi ovoga istraživanja, od prikupljanja literature, planiranja eksperimentalnog dijela, do njegovog izvođenja te obrade rezultata. Prilikom izvođenja eksperimentalnog rada pokazali su sklonost timskom radu. Samostalno su napisali rad i donijeli zaključke. Njihov interes za znanstveni rad ne čudi jer s prosjekom ocjena Ivan (4,6) i Matija (4,0) spadaju u ponajbolje studente svoje generacije. Vjerujem da su tokom izrade ovoga rada stekli važna iskustva te stekli saznanja o važnosti znanstvenog rada. Smatram da ovaj rad zadovoljava svim kriterijima izvrsnosti istaknutim Natječajem te predlažem rad studenata Ivana Sušnja i Matije Salopeka za Rektorovu nagradu u akademskoj godini 2014/2015. izv. prof. dr. sc. Ana-Marija Domijan Zavod za farmaceutsku botaniku Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu e-mail: [email protected] U Zagrebu, 29. 4. 2015. 2. Filip Blažević, Tamara Milekić Utjecaj lecitinsko-kitozanskih nanočestica s melatoninom na cijeljenje rane in vitro Cilj ovog istraživanja je priprava nanočestica kitozana i melatonina za topikalnu primjenu te evaluacija njihovog učinka na cijeljenje (epitelizaciju) rane in vitro u ovisnosti o sadržaju uklopljenog melatonina i svojstvima kitozana. Najnovija istraživanja u okviru razvoja funkcionalnih obloga temelje se na primjeni (bio)polimera s učinkom na cijeljenje rana, primjerice kroz utjecaj na migraciju i proliferaciju stanica kože, antimikrobni učinak te hemostatsko djelovanje. Razvijaju se polimerni terapijski nanosustavi koji mogu pridonijeti procesu cijeljenja ovisno o sadržaju djelatne tvari, polimernom sastavu i specifičnim fizičko-kemijskim svojstvima. U ovom radu lecitinsko-kitozanske nanočestice s melatoninom uspješno su pripravljene ionskom interakcijom između lecitina i kitozana. U pripravi nanočestica korištena su četiri tipa kitozana koja se međusobno razlikuju po molekulskoj masi (50-150 kDa ili 150-400 kDa) i/ili stupnju deacetilacije (75-90 % ili ˃90 %). Pripravljene su nanočestice srednjeg promjera od 245,2±2,8 do 277,1±7,6 nm, pozitivnog zeta-potencijala (23,4±0,9 do 32,5±1,2 mV) te zadovoljavajućeg sadržaja melatonina (3,8±0,3 do 4,3±0,4 %). Veličina i površinski naboj nanočestica ovisili su o molekulskoj masi i stupnju deacetilacije kitozana. Za sve ispitivane lecitinsko-kitozanske nanočestice dobiveni su slični bifazični profili produljenog oslobađanja melatonina. Izlaganje stanica suspenzijama nanočestica s melatoninom pri koncentraciji kitozana manjoj od 20 µgml-1 nije značajnije utjecalo na vijabilnost stanica, neovisno o tipu korištenog kitozana. Pri ispitivanju cijeljenja (epitelizacije)
Load more

Recommended publications
  • Back to People's Health in Croatia – Generating New Forms of Collective Agency
    ORIGINAL RESEARCH Back to People's Health in Croatia – Generating new forms of collective agency Snježana Ivčić, PhD; Lecturer Aleksandar Džakula, MD; Damir Martinović, MD; Valerija Žapčić, Abstract frequently focused on a single-disease approach and collaboration with the pharmaceutical This paper concerns new forms of industry. Such practices produced limited results; collective agency in the area of healthcare in hence improved forms of activism emerged. Croatia from 2015 until 2018. These new forms In this research, we illustrate their developed in the midst of the growing development using the example of three case privatization and commodification of health care studies of collective agency. The first case study is and the simultaneous decrease in the accessibility looking at the policy analysis and the activist to healthcare. group started by the Organization for Workers' Privatization has taken place slowly, but Initiative and Democratization (OWID); the continuously over the last 29 years. The traditional second one focuses on the informal group of civil society organizations in the field of medical students called U3 formed at the Andrija healthcare used to be characterized by a narrow set Štampar School of Public Health with the aim of of activities, with vertical structures, and were developing critical thinking; and the third case study considers the Karika Association, started as an attempt to rethink healthcare in the community. Snježana Ivčić, PhD, The main research methods employed Croatian Academy of Sciences and Arts, snjezana. included process tracing analysis and research data Email: [email protected] comparison aimed at showing the differences between the traditional and the new forms of Lecturer Aleksandar Džakula, MD, Škola narodnog zdravlja Andrija Štampar “/ healthcare activism, in addition to the secondary School of Public Health „Andrija Štampar “, sources of information such as scientific and Email: [email protected] professional literature.
    [Show full text]
  • Mental Health Services in Croatia
    91 COUNTRY PROFILE Mental health services in Croatia Sladjana Strkalj Ivezic,1 Martina Rojnic Kuzman2 and Maja Silobrcic Radic3 1Day Hospital and Community Rehabilitation Centre, Psychiatric Hospital Vrapce, Bolnicka cesta 32, 10090 Zagreb, Croatia, email sladjana.ivezic@bolnica-vrapce 2Department of Psychiatry, Zagreb University Hospital Centre and Zagreb School of Medicine, Croatia 3Croatian National Institute of Public Health, Croatia he Republic of Croatia is in central Europe, on the The health budget is covered by social insurance and is TMediterranean. A large majority of its 4 440 000 in- tax based. There is no separate budget allocation for mental habitants are Croats (89.6%). The main religion is Roman health, except for drug addictions. Basic healthcare is obliga- Catholicism (88%). Sixteen per cent of the population is tory for all and is provided by the Croatian Health Insurance aged over 65 years. Croatia was a part of Yugoslavia after Institute. This covers the treatment of all mental illnesses and the Second World War until 1991, when Croatia declared the cost of antipsychotic drugs. Supplementary and private independence. Following the declaration, Croatia was insurance are possible but uncommon. attacked by the Yugoslav army and by Serbia and suffered a devastating war (1991–95). The transition had conse- quences for mental health, for example a dramatic rise in Mental health service delivery the prevalence of post-traumatic stress disorder, especially among soldiers. The majority of soldiers received appro- Although GPs are highly accessible, psychiatric diagnoses priate psychiatric treatment; there has, however, been an com prised only 4.8% of all GP diagnoses in 2007 (CNIPH, increase in claims motivated by secondary gain, as a result 2008) and most service provision for serious mental illness is of government policy.
    [Show full text]
  • Croatia 60 Ana Borovecˇki
    Croatia 60 Ana Borovecˇki Austria Hungary Zagreb Croatia Bosnia and Herzegovina Introduction In Croatia, the impetus for the developments in the field of bioethics were the changes in the political system. Croatia used to be a part of the former Socialist Federative Republic of Yugoslavia. In the 1990s, the socialist political paradigm was abandoned and the democratic changes began. Thus, Croatia entered the same process as the other countries in the Region of East, Central, and Southeast Europe. The transition from a socialist to a democratic society for Croatia was further complicated by the Serbian aggression and the war experienced in the 1990s (Borovecki, ten Have, & Oreskovic, 2004). A. Borovecˇki School of Medicine, Andrija Stampar School of Public Health, University of Zagreb, Zagreb, Croatia e-mail: [email protected]; [email protected] H.A.M.J. ten Have, B. Gordijn (eds.), Handbook of Global Bioethics, 1049 DOI 10.1007/978-94-007-2512-6_15, # Springer Science+Business Media Dordrecht 2014 1050 A. Borovecˇki Bioethics Development In Croatia, the subject of medical ethics, or bioethics, was introduced into the curriculum in the early 1990s at the medical schools of the University of Rijeka and the University of Zagreb. With the advent of the new political changes came the changes in the concept of a subject of medical ethics, which was until that time scarcely taught, mainly as a few hour lecture and seminar at the Zagreb School of Medicine. Moreover, the previously taught obligatory subject of Marxism was abandoned leaving a place for the introduction of a new course in the medical curriculum.
    [Show full text]
  • Partnership Agreement Republic of Croatia 2014HR16M8PA001.1.3
    Partnership Agreement Republic of Croatia 2014HR16M8PA001.1.3 SECTION 1A 1. ARRANGEMENTS TO ENSURE ALIGNMENT WITH THE UNION STRATEGY OF SMART, SUSTAINABLE AND INCLUSIVE GROWTH AS WELL AS THE FUND SPECIFIC MISSIONS PURSUANT TO THEIR TREATY-BASED OBJECTIVES, INCLUDING ECONOMIC, SOCIAL AND TERRITORIAL COHESION 1.1. An analysis of disparities, development needs, and growth potentials with reference to the thematic objectives and the territorial challenges and taking account of the National Reform Programme, where appropriate, and relevant country-specific recommendations adopted in accordance with Article 121(2) TFEU and relevant Council recommendations adopted in accordance with Article 148(4) TFEU 1.1.1 Macroeconomic situation The declining trend of economic activity in Croatia continued in 2013 for the 5th year in a row. According to preliminary data of the Croatian Bureau of Statistics (CBS), 2013 ended with a drop in economic activity of 1.0% in comparison to 2012, which represents a cumulative drop of 11.9% in comparison to 2008. The main macroeconomic indicators of the Croatian economy in the period 2008 to 2012 are given in Table 1 in Annex 1 of this Partnership Agreement (PA). The most significant contribution to the real fall of the gross domestic product (GDP) from the expenditure side in 2013 came from a 1.8% drop in exports of goods and services, and a 1.0% decline in household consumption. All other components from the expenditure side of GDP recorded a real year-on-year decline, with the exception of government consumption (which grew slightly by 0.5%). The drop in household consumption in 2013 was the consequence of the exceptionally negative trends on the labour market and continued deleveraging of the household sector.
    [Show full text]
  • Croatia: National Climate Vulnerability Assessment (ENG)
    REPUBLIC OF CROATIA CLIMATE VULNERABILITY ASSESSMENT REPUBLIC OF CROATIA CLIMATE VULNERABILITY ASSESSMENT REPUBLIC OF CROATIA © Zavisa Simac, Ksenija Vitale. Climate Vulnerability Assessment: Croatia. Zagreb, May 2012 Copies of all or part of this study may be made for non-commercial use, providing the source is acknowledged. The SEEFCCA would appreciate receiving details of its use. Requests for commercial reproduction should be directed to the SEEFCCA at [email protected]. The opinions and recommendations expressed in this study do not necessarily represent the official policy of the SEEFCCA or individual National Red Cross Societies or project partners in this IPA project. The designations used do not imply the expression of any opinion on the part of SEEFCCA concerning the legal status of a territory or of its authorities. The copyright of each photo used in this study is indicated. This publication has been produced with the assistance of the European Union. The contents of this publication are the sole responsibility of Zaviša Simac and Ksenija Vitale and can in no way be taken to reflect the views of the European Union. www.seeclimateforum.org www.facebook.com/seeforumoncca [email protected] Editor: Croatian Red Cross Author: Zaviša Simac, Ksenija Vitale Advisors: Sonja Greiner, Marinko Metlicic, Louisa Whitlock Design: Imre Sebestyén, jr. / UNITgraphics.com Cover image: © iStockphoto.com/enderbirer Print: UVEZ Ltd. Zaprešić, Hrvatska REPUBLIC OF CROATIA ACRONYMS CBS Croatian Bureau of Statistics CDM Clean Development
    [Show full text]
  • Reclaiming Public Health Care in Europe
    Reclaiming Public Health Experiences and Insights from Europe This publication is the result of contributions from many researchers, activists, and organizations across Europe (and beyond!). We are in immense appreciation of the tireless work conducted by Viva Salud, the European Network against Privatization and Commercialization of Health and Social Protection, Centro di Salute Internazionale e Interculturale, Association ESE, the Centre for Development of Workers' Participation, the Life Quality Improvement Organization Karika, Médecine pour le Peuple, and the Action Platform Health and Solidarity. We are also in appreciation of the endless efforts of all People’s Health Movement Europe country circles that have built the basis for this research over the past several years. A special thanks goes to those who made the case studies happen–not only writing them but also by supporting the research for this collection in other ways. Desirée Enlund, Dominika Gornaľová, Eva Gallova, Jasper Thys, and Nina Rajković: thanks a ton for all the effort you put into developing the selected case studies. And a final thanks to the organizations that offered infrastructural support for the development of the case studies—People’s Health Movement Europe, Organization for Workers’ Initiative and Democratization, Institute for Political Reclaiming Public Health: Experiences and Insights from Europe Edited by Leigh Kamore Haynes and Ana Vračar Designed by Leigh Kamore Haynes Research coordination Ana Vračar JUNE 2021 People’s Health Movement Europe phmovement.org
    [Show full text]
  • English Summaries
    Public Disclosure Authorized World Bank Report Long-Term Care and Ageing Case Studies - Bulgaria, Croatia, Latvia and Poland Public Disclosure Authorized NOVEMBER , 2010 Public Disclosure Authorized E UROPE AND C ENTRAL A SIA R EGION H UMAN DEVELOPMENT DEPARTMENT Public Disclosure Authorized ACRONYMS AND ABBREVIATIONS ADL Activities of Daily Living CIA Central Intelligence Agency BGN Bulgarian Lev EASHD East Asia Human Development ECSHD Europe and Central Asia Human Development EU European Union EUROSTAT European Office for Statistics GDP Gross Domestic Product HRK Croatian Kuna IPH Institute for Public Health LTC Long Term Care MoHSW Ministry of Health and Social Welfare MoFVIS War Veterans and Intergenerational Solidarity NATO North Atlantic Treaty Organization NGO Non Governmental Organization NOSOSCO Nordic Social-Statistical Committee OECD Organization for Economic Development and Co-operation PLZ Polish Zloty RISAA Rules for the Implementation of Social Assistance Act SAA Social Assistance Act SHA System of Health Accounts SWH Social Welfare Home UN United Nations UNDP United Nations Development Project WHO World Health Organization Vice President: Philippe Le Houerou, ECAVP Country Director: Peter Harrold, ECCU5 Sector Director: Tamar Manuelyan Atinc, ECSHD Sector Manager: Abdo Yazbeck, ECSHD Task Team Leader: Sarbani Chakraborty, ECSHD ACKNOWLEDGEMENTS This report was prepared by a team led by Sarbani Chakraborty (Senior Health Specialist and Task Team Leader, EASHD) and consisting of Johannes Koettl (Economist, ECSHD) and Azada
    [Show full text]
  • Country Report Croatia 2017 Including an In-Depth Review on the Prevention and Correction of Macroeconomic Imbalances
    EUROPEAN COMMISSION Brussels, 22.2.2017 SWD(2017) 76 final COMMISSION STAFF WORKING DOCUMENT Country Report Croatia 2017 Including an In-Depth Review on the prevention and correction of macroeconomic imbalances Accompanying the document COMMUNICATION FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT, THE COUNCIL, THE EUROPEAN CENTRAL BANK AND THE EUROGROUP 2017 European Semester: Assessment of progress on structural reforms, prevention and correction of macroeconomic imbalances, and results of in-depth reviews under Regulation (EU) No 1176/2011 {COM(2017) 90 final} {SWD(2017) 67 final to SWD(2017) 93 final} EN EN CONTENTS Executive summary 1 1. Economic situation and outlook 4 2. Progress with country-specific recommendations 10 3. Summary of the main findings from the MIP in-depth review 13 4. Reform priorities 19 4.1. Public finances 19 4.2. Private sector debt and financial sector 24 4.3. Labour market, social policies and education 31 4.4. Business environment and investment 39 4.5. Public sector governance 48 A. Overview table 56 B. MIP Scoreboard 61 C. Standard tables 62 References 67 LIST OF TABLES 1.1. Key economic, financial and social indicators — Croatia 9 2.1. Summary table on 2016 CSR assessment 11 3.1. MIP Matrix 17 4.1.1. Tax brackets in PIT (HRK / month) 22 4.2.1. Financial soundness indicators, all banks 28 B.1. The MIP Scoreboard for Croatia 61 C.1. Financial market indicators 62 C.2. Labour market and social indicators 63 C.3. Labour market and social indicators (continued) 64 C.4. Product market performance and policy indicators 65 C.5.
    [Show full text]
  • Dokument Hr. Eng
    INTERDISCIPLINARNO PODRUČJE STUDENTSKI ZBOR SVEUČILIŠTA U ZAGREBU 1. Vedran Bukvić, Ekonomski fakultet, Martin Ivanković, Kineziološki fakultet, Petar Labrović, Prirodoslovno-matematički fakultet, Mario Mašić, Medicinski fakultet, Anamarija Mitar, Fakultet kemijskog inženjerstva i tehnologije, Gabrijela Mitar, Prehrambeno-biotehnološki fakultet, Josip Papak, Hrvatski studiji, Ana Sikavica, Akademija dramske umjetnosti, Mate Vukšić, Fakultet političkih znanosti, Pietro Boban, Akademija likovnih umjetnosti 147 sekundi za Keniju Tragičnim napadom na akademsku zajednicu 2. travnja 2015. godine u Keniji je ubijeno 147 studenata na sveučilišnom kampusu u Garissi. Europu je dva tjedna ranije, 24. ožujka potresla smrt 150 putnika leta 9525, namjerno srušenog u francuskim Alpama. Tom prilikom stradali su pretežno Europljani, državljani Njemačke i Španjolske. Ova dva događaja drastično su se razlikovala po odjeku u javnosti. Točno dva tjedna nakon tog prešućenog događaja, inicijativom “147 sekundi za Keniju” hrvatska studentska zajednica solidarizirala se sa obiteljima žrtava i skrenula pozornost na tragediju i studentske žrtve terorizma. Cilj inicijative bio je senzibilizirati hrvatsku i međunarodnu javnost i potaknuti na širu raspravu civilnog sektora, javnih institucija i akademske zajednice o događaju u Keniji i kontekstu sukoba u kojemu se tragedija dogodila. Tog četvrtka, 16. travnja u 14 sati i sedam minuta, 147 studenata leglo na površinu ispred Hrvatskog narodnog kazališta i ostati nepomično 147 sekundi. Prema procjeni organizatora dodatnih dvjestotinjak studenata i građana Grada Zagreba. Šime Strikoman, renomirani hrvatski fotograf, inicijativu studenata ovjekovječi je milenijskom fotografijom koja je zajedno sa studentskim manifestom obišla svijet. 2. Studenti Studentskog doma Stjepan Radić (akademska godina 2013./14.) i Studentski zbor Sveučilišta u Zagrebu Studentska inicijativa "Studentski val pomoći" „Studentski val pomoći“ naziv je studentske inicijative za pomoć poplavljenim područjima na području Republike Hrvatske i Bosne i Hercegovine.
    [Show full text]
  • Ehealth Interoperability in Croatia Getting Ready for the Connecting Europe Facility (CEF)
    eHealth Interoperability in Croatia Getting ready for the Connecting Europe Facility (CEF) Vanja Pajić Croatian Health Insurance Fund (HZZO), Croatia [email protected] June 9th, 2016 eHealth Week Amsterdam 2016 1 KEY TOPICS INTRODUCTION Croatian Healthcare System: Overview CRO-EU Cross-Border Healthcare PRIORITY AREAS FOR INFORMATION SHARING IN CRO & EU eHealth Services in Croatia: eP/PS/EHR Future of Cross-border healthcare in Croatia under Connecting Europe Facility (CEF) CROATIAN EXPERIENCES & WAY FORWARD eHealth Services Provision Obstacles to eHealth Service Provision June 9th, 2016 eHealth Week Amsterdam 2016 2 Croatian Healthcare System: Overview 4.3M insured persons Physician Nurse 2.300+ GP offices Application Application Hospital General practitioner 1.300+ pharmacies Central Pediatrician 1.000+ specialist health care offices ehealth Laboratory platform Gynecologist 65 hospitals Electronic Healthcare 1 state insurance Record Portal Patient Dentist Pharmacy Register System Messaging Health & business 1 Central eHealth platform Resources logic Register School Medicine Health Insurance Fund (Information System) Specialist Public Health Institution care offices Ministry of Health (Information System) (Information System) June 9th, 2016 eHealth Week Amsterdam 2016 3 CRO-EU Cross-border Healthcare EU Cross-border data exchange Croatia is getting ready for EU cross-border cooperation (Projects: epSOS, EXPAND, JAseHN, Assess-CT etc.) Croatia has applied for CEF eHealth funding June 9th, 2016 eHealth Week Amsterdam 2016
    [Show full text]
  • Italy – Croatia Cross-Border Cooperation Programme 2014-2020
    European Territorial Cooperation Italy – Croatia Cross-border Cooperation Programme 2014-2020 2nd DRAFT August 2014 1/124 Italy - Croatia Cross-border Cooperation Programme 2014 - 2020 draft 2.0 CCI Title Italy - Croatia Cross-border Cooperation Programme 2014 - 2020 Version First Year 2014 Last Year 2020 Eligible from 1 January 2014 Eligible until 31 December 2023 EC Decision Number EC Decision Date MS amending decision N. MS amending date MS amending decision entry into forcer date NUTS regions covered by HR031 Primorsko-goranskažupanija the cooperation programme HR032 Ličko-senjskažupanija HR033 Zadarskažupanija HR034 Šibensko-kninskažupanija HR035 Splitsko-dalmatinskažupanija HR036 Istarskažupanija HR037 Dubrovačko-neretvanskažupanija HR04D Karlovačkažupanija ITF12 Teramo ITF13 Pescara ITF14 Chieti ITF22 Campobasso ITF44 Brindisi ITF45 Lecce ITF46 Foggia ITF47 Bari ITF48 Barletta-Andria-Trani ITH35 Venezia ITH36 Padova ITH37 Rovigo ITH41 Pordenone ITH42 Udine ITH43 Gorizia ITH44 Trieste ITH56 Ferrara ITH57 Ravenna ITH58 Forlì-Cesena ITH59 Rimini ITI31 Pesaro e Urbino ITI32 Ancona ITI33 Macerata ITI34 Ascoli Piceno ITI35 Fermo 2/124 Italy - Croatia Cross-border Cooperation Programme 2014 - 2020 draft 2.0 SECTION 1. STRATEGY FOR THE COOPERATION PROGRAMME'S CONTRIBUTION TO THE UNION STRATEGY FOR SMART, SUSTAINABLE AND INCLUSIVE GROWTH AND THE ACHIEVEMENT OF ECONOMIC, SOCIAL AND TERRITORIAL COHESION 10 1.1. Strategy for the cooperation programme's contribution to the Union strategy for smart, sustainable and inclusive growth and to the achievement of economic, social and territorial cohesion ............................... 10 1.1.1. Description of the cooperation programme’s strategy for contributing to the delivery of the Union strategy for smart, sustainable and inclusive growth and for achievingeconomic, social and territorial cohesion ...........................................................
    [Show full text]
  • Country Report Croatia 2018 Including an In-Depth Review on the Prevention and Correction of Macroeconomic Imbalances
    EUROPEAN COMMISSION Brussels, 7.3.2018 SWD(2018) 209 final COMMISSION STAFF WORKING DOCUMENT Country Report Croatia 2018 Including an In-Depth Review on the prevention and correction of macroeconomic imbalances Accompanying the document COMMUNICATION FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT, THE COUNCIL, THE EUROPEAN CENTRAL BANK AND THE EUROGROUP 2018 European Semester: Assessment of progress on structural reforms, prevention and correction of macroeconomic imbalances, and results of in-depth reviews under Regulation (EU) No 1176/2011 {COM(2018) 120 final} EN EN CONTENTS Executive summary 1 1. Economic situation and outlook 4 2. Progress with country-specific recommendations 9 3. Summary of the main findings from the Macroeconomic Imbalance Procedure in•depth review 13 4. Reform priorities 18 4.1. Public finances* and taxation 18 4.2. Private sector debt and financial sector* 24 4.3. Labour market, social policies and education* 31 4.4. Competitiveness and investment* 39 4.5. Public governance* 47 Annex A: Overview table 54 Annex B: Macroeconomic Imbalance Procedure scoreboard 60 Annex C: Standard tables 61 References 67 LIST OF TABLES Table 2.1: CSR progress 11 Table 3.1: MIP Matrix 16 Table 4.1.1: Tax wedge comparison with peers 21 Table 4.2.1: Financial soundness indicators, all banks in Croatia 29 Table 4.5.1: Hospital beds by type, per 100 000 inhabitants, 2015 52 Table B.1: The MIP scoreboard for Croatia (AMR 2018) 60 Table C.1: Financial market indicators 61 Table C.2: Headline Social Scoreboard indicators 62 Table C.3:
    [Show full text]