SQF Cannabis Definitions Guide 1 Definit Ions Cannabis

Total Page:16

File Type:pdf, Size:1020Kb

SQF Cannabis Definitions Guide 1 Definit Ions Cannabis Definit ions Cannabis A Acidic Form Natural cannabinoid form from within the trichom es of raw cannabis flowers that have a carboxyl ring or group (COOH) attached to their chain. Alcohol Ext ract ion Process by which the cannabis plant is stripped of essential oils and trichom es using ethyl or isopropyl alcohol. Once the extra plant m aterial is filtered out and the rem aining alcohol is evaporated, sticky hash oil rem ains. B Broad Spect rum Unrefined extract from the hem p plant that has not been refined to contain Hem p Oil/Ext ract only specific cannabinoids and plant parts, but one or m ore constituents (e.g. THC) has been rem oved. But ane Hash Oil Process by which cannabis flowers are treated with butane creating an Ext ract ion am ber resin known as wax or shatter. This process allows tetrahydrocannabinol (THC) to becom e soluble. C Cannabinoid Any of a group of closely related com pounds which include cannabinol and the active constituents of cannabis. C21 or C22 (for the carboxylated form s) terpenophenolic com pounds, their carboxylic acids, analogs and transform ation products that act on cannabinoid receptors within the endocannabinoid system of anim als. Cannabinoids exist in three prim ary form s, distinguished by their sources: (a) phytocannabinoids, (b) endocannabinoids, and (c) synthetically produced cannabinoids SQF Cannabis Definitions Guide 1 Definit ions Cannabis C Cannabinoid Profile The com bined am ount of each cannabinoid that m ake up the plant or product. Cannabis Cannabis is a plant genus that produces three species of flowering plants: - Cannabis sativa L. a subspecies of Cannabis, is known as Hem p (see definition). Varieties have a THC content of less than 0.3%. Hem p is a non- psychoactive form of cannabis. Cannabis sativa L. is generally tall and random ly branched, high in fibre and grain. It is low in THC. Many fibre and grain products and industrial uses have been m ade from Cannabis sativa L. (hem p) - Cannabis indica has poor fibre quality and is used to m ake drugs for recreation and m edicine. The plant is relatively short, conical and densely branched. Cannabis indica tend to have a higher ? 9- THC and a lower Cannabidiol (CBD) content than C. sativa L. Marijuana (see definition), dependent on the strain, can have THC concentrations of 18% to 38%. - Cannabis Ruderalis a low- THC cannabis variety that is prim arily selected by breeders for its CBD- rich genetics. Unlike Cannabis sativa L. and indica, which use light cycles to flower, ruderalis is an ?autoflowering? variety, m eaning it flowers with age. Originating in Russia, ruderalis is a hardy plant that can survive harsh clim ates. CBC Cannabichrom ene, CBC is a powerful, non- psychoactive cannabinoid, has the sam e origins as both THC and CBD do in that they all stem from Cannabigerolic acid (CBGA). Cannabis plants produce CBGA, the precursor to three m ajor cannabinoids: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichrom enic acid (CBCA). SQF Cannabis Definitions Guide 2 Definit ions Cannabis C CBD Cannabidiol, CBD is the abbreviation for cannabidiol, one of the cannabinoids found in cannabis plants. CBD does not cause psychoactive effects (the ?high?) associated with THC. CBD is an antagonist to THC and is non- psychoactive as it blocks the form ation of 11- OH- THC and m itigates the psychoactive effects of THC. CBD has becom e popular for its therapeutic effects. CBDA Cannabidiolic Acid is an active ingredient in cannabis derived from the hem p plant and m olecular precursor to CBD. CBG Cannabigerol is a non- psychoactive cannabinoid that plays an im portant role in the biochem istry of the cannabis plant. CBG acts as a chem ical precursor to other cannabinoids such as THC and CBD. CBGA Cannabigerolic Acid is, the precursor to three m ajor cannabinoids: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichrom enic acid (CBCA). CBN Cannabinol, com es from the Cannabis sativa plant and serves as an indication of THC content and THC degradation. CFIA Canadian Food Inspection Agency is a regulatory agency that is dedicated to the safeguarding of food, anim als, and plants, which enhance the health and well- being of Canada's people, environm ent and econom y. Working under Health Canada is it responsible for ensuring com pliance to the Safe Food for Canadians Regulation. SQF Cannabis Definitions Guide 3 Definit ions Cannabis C Concent rat e (or Refers to any m aterial created by refining cannabis flowers or by synthesizing Ext ract ) phytocannabinoids. The substance is obtained by separating naturally occurring chem ical constituents of Cannabis, such as cannabinoids, from insoluble Cannabis plant m aterial by m echanical, chem ical, or other processes. Concentrates or extracts have m uch higher cannabinoid concentration. Som etim e referred to as Cannabis Extracts. They m ay: I. Contain solvents in allowable am ounts and Ingredients used to prom ote a desired physical state, texture, or flavor in the Cannabis Concentrate, but no other Ingredients; and II. Be intended for use in the production of Cannabis- Infused Products; or III. Be a finished product intended for hum an consum ption or use. Crude Hem p Is an unrefined extract that contains all com pounds found naturally occurring Oil/Ext ract in the Cannabis plant, including terpenes, essential oils and other cannabinoids from the hem p plant that has not been refined to contain only specific cannabinoids and plant parts. Also known as Full Spectrum Hem p Oil/Extract D DEA The Drug Enforcem ent Adm inistration is a United States federal law enforcem ent agency under the United States Departm ent of Justice, tasked with com bating drug trafficking and distribution within the United States. The DEA is the lead agency for dom estic enforcem ent of the Controlled Substances Act. Decarboxy lat ion The process by which, when exposed to heat, the carboxyl ring or group (COOH) is rem oved. During decarboxylation, Tetrahydrocannabinolic acid (THCA) is converted to THC and Cannabidiolic acid (CBDA) is converted to CBD (Cannabidiol). SQF Cannabis Definitions Guide 4 Definit ions Cannabis D Dosage/Dosing Individualized am ount of cannabinoids within a product. Dosing depends on titration, which is the process of increasing m edication am ounts until the desired effect is achieved. Dronabinol (Marinol A synthetic THC pharm aceutical approved in the U.S. for the reduction of and Sy ndros) nausea and vom iting in cancer chem otherapy and increased appetite in HIV- wasting disease. Dry Biom ass Dried whole of m illed plant m aterial of cultivars of Cannabis spp. DSHEA The Dietary Supplem ent Health and Education Act of 1994, is a 1994 statute of United States Federal legislation which defines and regulates dietary supplem ents. Under the act, supplem ents are effectively regulated by the FDA for Good Manufacturing Practices under 21 CFR Part 111. E Edibles (also see Edibles are m edicated edible goods that have been infused with cannabis Ingestible extracts. They are com m only baked goods such as cookies and brownies, but Cannabis- Infused options as varied as flavored coffee drinks, breads, and candies exist as well. Product) Dispensaries also often sell m arijuana- infused butters or oils for patients or consum ers to m ake their own edibles. Consum ing edibles m eans the active com ponents from the extracts require longer to take effect as they need to be absorbed through the digestive system . SQF Cannabis Definitions Guide 5 Definit ions Cannabis E Endocannabinoid Is a biological system com posed of a group of receptors that m ake up a very Sy st em (ECS) com plex regulatory system throughout the hum an brain, body, and central and peripheral nervous system s. The m ain function of the ECS is to m aintain the body?s internal stability (hom eostasis) by adjusting the flow of neurotransm itters and regulating bodily functions, including appetite, sleep, em otion, and m ovem ent. Endocannabinoids Are endogenous (m ade within the body) lipid- based retrograde neurotransm itters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the vertebrate central nervous system (including the brain) and peripheral nervous system . Epidiolex A cannabidiol drug, approved by the Food and Drug Adm inistration in 2018 for treatm ent of epilepsy associated with Lennox?Gastaut syndrom e or Dravet syndrom e in patients 2 years of age and older. Ext ract ion The different processes by which cannabinoids within the plant can be extracted for use. These processes include alcohol extraction, butane hash oil extraction, etc. F FDA The Food and Drug Adm inistration (or also USFDA) is a federal agency of the United States Departm ent of Health and Hum an Services, one of the United States federal executive departm ents. The FDA is responsible for protecting and prom oting public health through the control and supervision of food safety, tobacco products, dietary supplem ents, prescription and over- the- counter pharm aceutical drugs (m edications), vaccines, biopharm aceuticals, blood transfusions, m edical devices, electrom agnetic radiation em itting devices (ERED), cosm etics, anim al foods & feed and veterinary products. SQF Cannabis Definitions Guide 6 Definit ions Cannabis F Fem inized Fem inized plants com e from seeds that have been selectively bred to produce only fem ale plants. Since fem ale plants are the ones that produce flowers (which is where m ost of cannabis? cannabinoids are found), they are the only ones that are used to create cannabinoid containing products. Flow er Known as the hairy or sticky parts of the plant which are harvested for consum ption in various products, also known as the reproductive organs of the plant.
Recommended publications
  • Basic Cannabis Knowledge 101
    Basic Cannabis Knowledge 101 Cannabis is the genus of three species of flowering plants: Sativa and Indica and ruderalis (naturally lower in THC). Marijuana is the female cannabis plant in which flowers contain a percentage of cannabinoids and hold both medicinal and psychoactive properties. There are 488 chemical entities, and at least 66 are cannabinoid compounds. THC and CBD are not the only medicinally active compounds found in cannabis. Sativa plant grows taller, are lighter in color. The plant takes longer to flower and produces more Sativa cerebral effects. This plant is the largest of the three families. Symptom Relief: Depression, ADD, fatigue, Mood Disorder. Indica plants are shorter, bushier and produce Indica sedative physical effects. Symptom Relief: Pain, anxiety, insomnia, muscle spasms. Cannabis Ruderalis is a low-THC species of Ruderalis Cannabis. Very small plant and fast growing. What is Hemp? HEMP: Active Ingredient-CBD. No psychoactive effects. Contains Know the 20% or more of CBD and less than .3% of THC. Federally legal. Difference MARIJUANA PLANT: Active Ingredient-THC. Yes psychoactive effects (leaves and flowers). Contains 10% or more of CBD and more than 20% THC. Federally illegal Schedule II Drug. Many parts of the plant can be produced to make every day consumables. Hemp is produced from the male cannabis plant. CBD can be obtained from both hemp and marijuana, but hemp is the better choice as it does not contain THC. (Tetrahydrocannabinol). Hemp seed does not contain the psychoactive compound and will not get consumers high. It has shown to be beneficial for treating neurodegenerative diseases inflammation, autoimmune and neurodegenerative diseases.
    [Show full text]
  • Ethical Implications of Medical Marijuana Legalization
    DRUGS & SOCIETY: ETHICAL IMPLICATIONS OF MEDICAL MARIJUANA LEGALIZATION BARRY S. LEE, PSY D, MSW, LCSW, CADC HANNAH AHRENS & AUBREY ST. JOHN LOOKING THROUGH ROSE COLORED GLASSES? AREAS OF FOCUS ❑ Introductory Content ` (Barry Lee) ❑ Macro Perspective: Policy ➢ NASW Code of Ethics: (Aubrey St. John) Preamble ➢ Scheduling of Controlled Substances; ➢ Cannabis sativa Constitutional Commerce Clause ❑ Medical Use (Hannah Ahrens) ➢ Research findings/clinical studies’ ➢ NASW Code of Ethics: Ethical impact Principles ❑ Legal Factors/Parallels to Alcohol ➢ Patients’ stories & implications for (Barry Lee) further research ➢ “Straddling” MML and “Adult Use”: Beverage Alcohol INTRODUCTORY CONTENT: BARRY LEE NASW Code of Ethics Faith Integration About Cannabis sativa NASW CODE OF ETHICS: CORE VALUES ❑ Competence ❑ Integrity ❑ Dignity and Worth of the Person ❑ Service ❑ Importance of Human ❑ Social Justice Relationships NASW CODE OF ETHICS Ethical Standards 5.01 (d) Integrity of the Profession: “…should contribute to the knowledge base of social work and share with colleagues…and to share their knowledge at professional meetings….” 6.04 (a) Social and Political Action: “Social workers should be aware of the impact of the political arena…and advocate for changes in policy…to improve social conditions….” NASW CODE OF ETHICS Preamble "The primary mission of the social work profession is to enhance human well-being and help meet the basic human needs of all people...." NASW CODE OF ETHICS Preamble "A historic and defining feature of social work is the profession's
    [Show full text]
  • Psychedelic Resource List (PRL) Was Born in 1994 As a Subscription-Based Newsletter
    A Note from the Author… The Psychedelic Resource List (PRL) was born in 1994 as a subscription-based newsletter. In 1996, everything that had previously been published, along with a bounty of new material, was updated and compiled into a book. From 1996 until 2004, several new editions of the book were produced. With each new version, a decrease in font size correlated to an increase in information. The task of revising the book grew continually larger. Two attempts to create an updated fifth edition both fizzled out. I finally accepted that keeping on top of all of the new books, businesses, and organizations, had become a more formidable challenge than I wished to take on. In any case, these days folks can find much of what they are looking for by simply using an Internet search engine. Even though much of the PRL is now extremely dated, it occurred to me that there are two reasons why making it available on the web might be of value. First, despite the fact that a good deal of the book’s content describes things that are no longer extant, certainly some of the content relates to writings that are still available and businesses or organizations that are still in operation. The opinions expressed regarding such literature and groups may remain helpful for those who are attempting to navigate the field for solid resources, or who need some guidance regarding what’s best to avoid. Second, the book acts as a snapshot of underground culture at a particular point in history. As such, it may be found to be an enjoyable glimpse of the psychedelic scene during the late 1990s and early 2000s.
    [Show full text]
  • Conversion Characteristics of Some Major Cannabinoids from Hemp (Cannabis Sativa L.) Raw Materials by New Rapid Simultaneous Analysis Method
    molecules Article Conversion Characteristics of Some Major Cannabinoids from Hemp (Cannabis sativa L.) Raw Materials by New Rapid Simultaneous Analysis Method Byeong Ryeol Ryu 1,† , Md. Jahirul Islam 1,2,† , Md. Obyedul Kalam Azad 1 , Eun-Ji Go 1, Md. Hafizur Rahman 1, Md. Soyel Rana 1, Young-Seok Lim 1,* and Jung-Dae Lim 1,* 1 Department of Bio-Health Convergence, Kangwon National University, Chuncheon 24341, Korea; [email protected] (B.R.R.); [email protected] (M.J.I.); [email protected] (M.O.K.A.); [email protected] (E.-J.G.); hafi[email protected] (M.H.R.); [email protected] (M.S.R.) 2 Physiology and Sugar Chemistry Division, Bangladesh Sugarcrop Research Institute, Ishurdi, Pabna 6620, Bangladesh * Correspondence: [email protected] (Y.-S.L.); [email protected] (J.-D.L.); Tel.: +82-33-250-6474 (Y.-S.L.); +82-33-540-3323 (J.-D.L.) † These authors contribute equally. Abstract: This study was carried out to develop a high-performance liquid chromatography method for short-time analysis of the main cannabinoids in the inflorescence of hemp (Cannabis sativa L.). We also performed decarboxylation of the raw material using our advanced analysis technique. In this study, the UV spectrum was considered to analyze each of the four common cannabinoids, solvents, and samples, where the uniform elution of acidic cannabinoids without peak tailing and Citation: Ryu, B.R.; Islam, M..J.; acids was tested. Optimal results were obtained when readings were taken at a wavelength of 220 nm Azad, M..O.K.; Go, E.-J.; Rahman, using water and methanol containing trifluoroacetic acid as mobile phases in a solvent gradient M..H.; Rana, M..S.; Lim, Y.-S.; Lim, J.-D.
    [Show full text]
  • Microwave-Assisted Industrial Scale Cannabis Extraction
    technologies Article Microwave-Assisted Industrial Scale Cannabis Extraction Marilena Radoiu 1,2,*, Harmandeep Kaur 1, Anna Bakowska-Barczak 1 and Steven Splinter 1 1 Radient Technologies Inc., Edmonton, AB T6E 6S4, Canada; [email protected] (H.K.); [email protected] (A.B.-B.); [email protected] (S.S.) 2 Microwave Technologies Consulting, 69140 Lyon, France * Correspondence: [email protected]; Tel.: +33-651-285174 Received: 10 July 2020; Accepted: 18 August 2020; Published: 21 August 2020 Abstract: Cannabis is a flowering plant that has long been used for medicinal, therapeutic, and recreational purposes. Cannabis contains more than 500 different compounds, including a unique class of terpeno-phenolic compounds known as cannabinoids. D9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most extensively studied cannabinoids. They have been associated with the therapeutic and medicinal properties of the cannabis plant and also with its popularity as a recreational drug. In this paper, an industrial method for cannabis extraction using 915 MHz microwaves coupled with continuous flow operation is presented. The main advantages of the microwave-assisted extraction (MAE) are associated to the continuous-flow operation at atmospheric pressure which allows for higher volumes of biomass to be processed in less time than existing extraction methods, with improved extraction efficiency leading to increased final product yields, improved extract consistency and quality because the process does not require stopping and restarting material flows, and ease of scale-up to industrial scale without the use of pressurised batch vessels. Moreover, due to the flexibility of changing the operation conditions, MAE eliminates additional steps required in most extraction methods, such as biomass decarboxylation or winterisation, which typically adds at least a half day to the extraction process.
    [Show full text]
  • What Is Hemp Part 1.Indd
    WHAT IS HEMP? PART 1 WHAT IS HEMP? A FEW THINGS TO KNOW! 01 •Hemp is a variety of Cannabis sativa referred to as Cannabis Sativa L. • Contains high levels of CBD & low levels of the psychotropic compound THC • The psychoactive properties of cannabis show up at around 5% so marijuana with lower levels of THC may not be psychoactive. • Legally all cannabis plants with below .3% THC are classified as hemp • Historically hemp has been bred for its fiber, but in more recent years has been cultivated for its flowers which produce high levels of CBD RELATED ARTICLES ONLINE https://www.leafly.com/news/cannabis-101/what-is-cbd https://www.leafly.com/news/cannabis-101/what-is-cbd-oil https://www.leafly.com/news/cbd/cbd-vs-thc WHAT IS HEMP? HOW ARE THESE PLANTS DIFFERENT? The various species of cannabis are still debated but these three species; Cannabis sativa, Cannabis indica, and Cannabis ruderalis, are the most widely accepted. The greatest differences between them are due to selective breeding for fiber, seed or high levels of certain cannabinoids (more on cannabinoids later). Their appearance and cultivation methods will vary based on the desired use of the final crop. HOW ARE THESE PLANTS DIFFERENT? CANNABIS SATIVA 01 • Indigenous to Eastern Asia • Used as a source of industrial fiber, seed, oil, food, recreation, religious practices and medicine • Requires at least 13 hours of light to stay in vegetative state CANNABIS INDICA 02 • Indigenous to Afghanistan • Mainly used for extraction and medical purposes due to high levels of THC • Requires 15-18 hours of light to stay in a vegetative state CANNABIS RUDERALIS 03 • Indigenous to central Europe, eastern Europe, and Russia • Used in Russian folk medicine and more recently for extracting its high levels of CBD • Transitions from veg to flower with time, not light cycle WHAT IS HEMP? LET’S TALK CANNABINOIDS! Cannabinoids are a diverse class of chemical compounds that occur naturally in the human body as endocannabinoids and in the cannabis plant as phytocannabinoids.
    [Show full text]
  • Medicinal Cannabis & Parkinson Disease
    Ankur Butala MD Assistant Professor of Neurology, Psychiatry & Behavioral Sciences DISCLOSURES I have no actual or potential conflicts of interest in relation to this presentation I will be discussing “off-label” uses of the following medications: Dronabinol (Marinol) Nabixmols (Sativex) Nabilone (Cesamet) 2 DISCLAIMER & PSA … FOR PATIENTS Cannabis = “Natural” “Natural” = Better or Benign 3 Prescription medication have more Scientific Evidence, Regulations and Quality Control than Medicinal Cannabis 4 Disclaimer & PSA … For Doctors Patients asking about medicinal cannabis … are NOT (generally) trying to get high or avoiding treatment may be implying that they are experiencing or are concerned about side-effects need counseling, education and engagement have an unaddressed or unmet need 5 Objectives & Propositions Inquiring about medicinal cannabis isn’t “strange” or “weird” Explaining that Cannabis is (relatively) safe Cannabis is effective reasonable for motor and neuropsychiatric symptoms of Parkinson Disease Cannabis is not simpler / cheaper / faster than “medication” 6 “Where do you find the strength to live when you suffer an incurable disease? After a 20- year battle with Parkinson's, Larry refuses to give up and will attempt the unthinkable: a 300-mile bike ride across South Dakota, a journey of hope for anyone facing a life altering illness. In this intimate portrait of courage, love, and community, Larry will prove that if you love life, you fight for it.” HTTP://A.CO/D/7HSG1OI 7 Medicinal cannabis Cannabis has roots as old as humanity isn’t strange or weird WESTWARD MIGRATION AND SACRAMENTAL USE Al-Qanun fi-I-tibb (“The Canon of Medicine”) Abu Ali Sina 9 MIDDLE AGE & RENAISSANCE APOTHECARIES 10 200+ Cannabis elixirs, extracts and tinctures were available in US Pharmacies by 1937 REEFER MADNESS Dir.
    [Show full text]
  • Medical Cannabis, Headaches, and Migraines: a Published 08/24/2021
    Open Access Review Article DOI: 10.7759/cureus.17407 Review began 08/06/2021 Review ended 08/15/2021 Medical Cannabis, Headaches, and Migraines: A Published 08/24/2021 © Copyright 2021 Review of the Current Literature Poudel et al. This is an open access 1 2 1 3 1 article distributed under the terms of the Sujan Poudel , Jonathan Quinonez , Jinal Choudhari , Zachary T. Au , Sylvia Paesani , Armond K. Creative Commons Attribution License Thiess 1 , Samir Ruxmohan 4 , Mobashir Hosameddin 5 , Gerardo F. Ferrer 6 , Jack Michel 7 CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any 1. Division of Research and Academic Affairs, Larkin Community Hospital, Miami, USA 2. Neurology/Osteopathic medium, provided the original author and source are credited. Neuromuscular Medicine, Larkin Community Hospital, Miami, USA 3. Family and Community Medicine, Larkin Community Hospital, Miami, Florida, USA 4. Neurology, Larkin Community Hospital, Miami, Florida, USA 5. Preventive Medicine, Larkin Community Hospital, Miami, USA 6. Psychiatry, Larkin Community Hospital, Miami, USA 7. Medicine, Larkin Health System, Miami, USA Corresponding author: Jonathan Quinonez, [email protected] Abstract Cannabis has been long used since ancient times for both medical and recreational use. Past research has shown that cannabis can be indicated for symptom management disorders, including cancer, chronic pain, headaches, migraines, and psychological disorders (anxiety, depression, and post-traumatic stress disorder). Active ingredients in cannabis that modulate patients' perceptions of their conditions include Δ9‐ tetrahydrocannabinol (THC), cannabidiol (CBD), flavonoids, and terpenes. These compounds work to produce effects within the endocannabinoid system to decrease nociception and decrease symptom frequency.
    [Show full text]
  • An Interview with Ethan Russo, MD
    Cannabis and Cannabinoid Research Volume 1.1, 2016 Cannabis and DOI: 10.1089/can.2015.29003.ebr Cannabinoid Research INTERVIEW Open Access The Cannabis sativa Versus Cannabis indica Debate: An Interview with Ethan Russo, MD Daniele Piomelli1,2,* and Ethan B. Russo3 Dr. Ethan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and Medical Director of PHYTECS, a biotechnology company researching and developing innovative approaches targeting the human endocannabinoid system. Previously, from 2003 to 2014, he served as Senior Medical Advisor and study physician to GW Pharmaceuticals for three Phase III clinical trials of SativexÒ for alleviation of cancer pain unresponsive to optimized opioid treatment and studies of EpidiolexÒ for intractable epilepsy. He has held faculty appointments in Pharmaceutical Sciences at the University of Montana, in Medicine at the University of Washington, and as visiting Professor, Chinese Academy of Sciences. He is a past President of the International Cannabinoid Research Society and former Chairman of the International Association for Cannabinoid Medicines. He serves on the Sci- entific Advisory Board for the American Botanical Council. He is the author of numerous books, book chapters, and articles on Cannabis, ethnobotany, and herbal medicine. His research interests have included correlations of historical uses of Cannabis with modern pharmacological mechanisms, phytopharmaceutical treatment of mi- graine and chronic pain, and phytocannabinoid/terpenoid/serotonergic/vanilloid interactions. Cannabis and Cannabinoid Research (Dr. Daniele Dr. Russo: D9-tetrahydrocannabinol is, of course, the Piomelli: CCR): I would like to start with a few pre-eminent psychoactive component of Cannabis. questions that should not be too contentious. D8-tetrahydrocannabinol, a more heat-stable compo- First off, what is the geographic origin of the Can- nent, is probably slightly less psychoactive, but is pres- nabis plant? ent only in trace amounts or as an artifact of laboratory analysis.
    [Show full text]
  • Medical Marijuana and Include Our Role in the Definition of the Prescribing ‘Physician’.”
    APMA 2019 THE NATIONAL MEDICAL CANNABIS FOR PAIN MANAGEMENT Disclosures Wenjay Sung, DPM, FACFAS The following relationships with commercial interests related to this presentation existed during the past 12 months: NONE AUDIENCE RESPONSE SYSTEM INSTRUCTIONS WWW.POLLEV.COM/WENJAYSUNG OR TEXT WENJAYSUNG TO 37607 The News “The Marijuana Freedom and Opportunity Act removes marijuana from the list of scheduled substances under the 1970 Controlled Substances Act, allowing states to decide how to handle marijuana possession” Genus: Cannabaceae Cannabis sativa Cannabis ruderalis Cannabis indica Dioecious, Flowering Herb Male Female Hemp Resin Flower Buds “Hashish” “Marijuana” “Marijuana” Cannabinoids Tetrahydrocannabinol Cannabidiol THC/CBD At least 500 other active chemicals in marijuana Act on cannabinoid receptors in cells that repress neurotransmitter release in the brain (CNS) Gets you “HIGH” Act on cannabinoid receptors in cells that repress neurotransmitter release in the brain (CNS) Does NOT get you “HIGH” In 1970, Congress and the Nixon Administration determined that Cannabis and its derivatives are dangerous drugs and that illegal distribution and sale is a serious crime Doctor’s Recommendation Podiatrist Role? • “We must clarify the role of podiatric physicians in prescribing medical marijuana and include our role in the definition of the prescribing ‘physician’.” • “We must challenge state laws regarding medical marijuana, much like the scope of practice issues past and present.” Why does it matter? • “The inability to obtain a license
    [Show full text]
  • Colorado Cannabis Faqs
    Cannabis FAQ We get many inquiries about what is happening in Colorado after the two state constitutional amendments regulating cannabis. We hope that this document will provide some basic information and where to find resources. What are the components of marijuana? Marijuana is comprised of hundreds of individual molecules known as cannabinoids and terpenes. Cannabinoids are molecules unique to cannabis that can produce a wide variety of both therapeutic and adverse effects. Approximately 66 cannabinoids have been discovered, yet due to limited research, we only know a fair amount about a select few. The most well-known cannabinoid is Delta-9 Tetrahydrocannabinol. Next in line is Cannabidiol (CBD). Terpenes are organic molecules that emit aromas. These molecules are responsible for the unique smells and flavors that cannabis brings to the table and also can produce physiological effects. Common terpenes found in cannabis include Myrcene, Linalool, and Limonene. The cannabinoid and terpene profile of any cannabis plant make up its chemotype which helps us to predict what the effects will be. adai.uw.edu/marijuana/factsheets/cannabinoids.htm (Cannabinoid Factsheet) How is marijuana used? There are many ways to use marijuana and each one affects users differently. Factors include dosage, subject’s body composition, and tolerance. Marijuana can be smoked like a cigarette (a joint) or a cigar (a blunt). Marijuana can also be smoked in a pipe; small glass (spoon) and water (bong) pipes are common. Sometimes people mix it in food and eat it or brew it as a tea (edibles). Smoking oils, concentrates, and extracts from the marijuana plant are also popular.
    [Show full text]
  • Medical Cannabis: a Guide to Access Glossary of Terms
    Medical Cannabis: A Guide to Access Glossary of Terms Aroma Cannabinoid receptors Aroma describes smell and/or taste. Aroma is very personal and Cannabinoid receptors are proteins in the body — found perceived differently by different people. For medical cannabis, predominantly in the brain, nervous system and immune system aroma also depends on the strain and can range from earthy, — that bind cannabinoid molecules. The two main cannabinoid skunky, to even citrusy. receptors are called CB1 and CB2, and over the past 20 years we’ve begun to gain a better understanding of their role in our Blend bodies. The binding of cannabinoids to their receptors triggers a chain of biochemical events within a person. The cannabinoid A cannabis blend combines different strains (see page 3) to system — endocannabinoid molecules and their receptors — achieve a particular desired effect, similar to the way that helps regulate pain, mood, appetite and memory. Cannabinoids different tea leaves are blended to create a particular flavor introduced externally, such as from medical cannabis, bind (e.g., English Breakfast). to these receptors and produce the same effect as our body’s own endocannabinoids, except at a higher concentration, thus Bud producing more intense effects. The cannabis plant’s fluffy-looking flower is referred to as a bud. Buds are used for medical cannabis because they have the Cannabis, marijuana highest cannabinoid concentrations in the cannabis plant. Cannabis is a scientific name and marijuana is a slang term; however, they refer to the same thing and are often used Cannabidiol (CBD) interchangeably. Medical cannabis is sometimes used by people who live with a chronic illness as a way to deal with Cannabidiol, also called CBD, is the second most and alleviate symptoms, such as pain and fatigue.
    [Show full text]