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Official Journal of AFSTAL, ECLAM, ESLAV, FELASA, GV-SOLAS, ILAF, LASA, NVP, SECAL, SGV, SPCAL Volume 52 Number 6 December 2018 ISSN 0023-6772 Laboratory Animals THE INTERNATIONAL JOURNAL OF LABORATORY ANIMAL SCIENCE, MEDICINE, TECHNOLOGY AND WELFARE Official Journal of AFSTAL, ECLAM, ESLAV, FELASA, GV-SOLAS, ILAF, LASA, NVP, SECAL, SGV, SPCAL Published on behalf of Laboratory Animals Ltd. journals.sagepub.com/home/lan by SAGE Publications Ltd. We build the model, you do the research. Ever considered the consequences of using a model verification. Erroneous modifications can lead to the carrying the wrong genes? The advent of recent generation of mutant and transgenic lines carrying genome editing technologies like CRISPR/Cas9 are non-functional alleles or unwanted mutations. These revolutionising the way new models are created, but faulty models can seriously impact your research their impact on the mouse genome requires careful programme, wasting resources on misleading results. Learn how we can help at www.criver.com/modelcreation Volume 52 Number 6 December 2018 Contents Review Article The African spiny mouse (Acomys spp.) as an emerging model for development and regeneration 565 G Pinheiro, DF Prata, IM Arau´jo and G Tiscornia Original Articles Diurnally active rodents for laboratory research 577 R Refinetti and GJ Kenagy Anaesthetic effects of alfaxalone administered intraperitoneally alone or combined with dexmedetomidine and fentanyl in the rat 588 M Arenillas and IAG de Segura Refinement and reduction through application of a quantitative score system for estimation of TB-induced disease burden using computed tomography 599 SA Sharpe, D Smyth, A McIntyre, F Gleeson and MJ Dennis Color matters: They would choose if they could (see)! 611 T Nitezki, N Schulz and S Kra¨mer Four simple ways to increase power without increasing the sample size 621 SE Lazic Pigs are useful for the molecular study of bone inflammation and regeneration in humans 630 FL Lu¨thje, K Skovgaard, HE Jensen and LK Jensen News Registration is opened for the 14th FELASA Congress! 643 What does the GV-SOLAS actually do? 645 B Kra¨nzlin and N Linklater Meeting report GV-SOLAS annual conference 2018 646 C Johner En Espan˜a se presenta el primer informe anual del Acuerdo de Transparencia en Experimentacio´n Animal 649 S Vila Newly created title of the Diplomate Specialized Veterinarian in Laboratory Animal Science (Dipl. SVLAS) awarded by the Swiss Association of Veterinarians in Industry and Research (SAVIR) 653 M Heimann Calendar of events/Index to advertisers 656 *compared to previous generation Tunnel GP ARCADIA_210X280_DEF-PROFILI.indd 1 13/10/2018 12:30:35 Catalogue 2019 Request your free copy NOW AVAILABLE! at: finescience.de FINE SURGICAL INSTRUMENTS FOR RESEARCHTM .............................................................................................................................................................................................553 Laboratory Animals Subscription information Annual subscription (2018) including postage: AALAS Member, (print and electronic) [US$120]. Combined Institutional Rate (print and electronic) [£304/US$562]. Electronic only and print Editorial Board only subscriptions are available for institutions at a discounted Editor-in-Chief B Riederer rate. Note VAT is applicable at the appropriate local rate. 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Printed in Great Britain ...............................................................................................................................................................554 AFSTAL Secretary President Nicole Linklater Teresa Rodrigo Association Franc¸aise des Sciences et Faculty of Biology Techniques de I’Animal de Laboratoire Philipps University Vice President President Karl-von-Frisch Str. 8 Isabel Blanco Sebastian Paturance 35043 Marburg Vice President Germany Secretary Elodie Bouchoux (www.gv-solas.de) Clara Mun˜oz Secretariat: 28, rue Saint Dominique, 75007, Treasurer Paris, France David Mun˜oz (www.afstal.com) ILAF Israeli Laboratory Animal Forum Secretariat: c/Maestro Ripoll, 8, President 28006 Madrid, Amir Rosner Spain (www.secal.es) ECLAM Secretary European College of Laboratory Animal David Castel Medicine Neufeld Cardiac Research President Institute SGV Rony Kalman Sheba Medical Center Schweizerische Gesellschaft fu¨r Tel Hashomer 52621 Secretariat: PO Box 9101NL-6500 Versuchstierkunde Israel HB Nijmegen, The Netherlands Socie´te´ Suisse pour la Science des Animaux de (www.ilaf.org.il) (http://eslav-eclam.org/eclam) Laboratoire (Swiss Laboratory Animal Science Association) President ESLAV LASA Dr. Birgit Ledermann European Society of Laboratory Animal Laboratory Animal Science Association Secretary Veterinarians President Dr. med. vet. Andrina Zbinden President David Anderson Faculty of Science and Medicine Jose´ Manuel Sa´nchez-Morgado University of Fribourg Secretary General Ch. du Muse´e8 Honorary Secretary Miles Maxwell CH-1700 Fribourg, Switzerland Massimiliano Bardotti (www.naturalsciences.ch/organisations/sgv) PO Box 524,
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