Supplemental Table 1: Pancreatic Lesion Multiplicity in Ela-KRASG12D Mice at 14 Months of Age Depends on Genetic Background
Supplemental Table 1: Pancreatic lesion multiplicity in Ela-KRASG12D mice at 14 months of age depends on genetic background. Mouse Strain # Mice Lesion Multiplicity ± SD FVB-Tg(Ela-KRASG12D) 18 0.3 ± 0.6 G12D SWFVB-Tg(Ela-KRAS )F1 16 0.6 ± 1 G12D a C3FVB-Tg(Ela-KRAS )F1 14 4 ± 4 G12D a BALBFVB-Tg(Ela-KRAS )F1 16 8 ± 4 G12D a D2FVB-Tg(Ela-KRAS )F1 14 8 ± 4 G12D a B6FVB-Tg(Ela-KRAS )F1 18 11 ± 5 aSignificantly different from the FVB-Tg(Ela-KRASG12D) value by Wilcoxon rank sum test (P < 10-4) Supplemental Table 2 1 Supplemental Table 2: Positions of markers analyzed in linkage studies. a b c c c Marker Chrom Pos (cM) Pos (bp) B6xFVB BALBxFVB D2xFVB D1Mit70 1 17.8 32,733,289 B D1Mit5 1 32.8 63,862,105 IB D1Mit46 1 43.1 75,569,122 IB IB D1Mit83 1 52 88,043,561 IB D1Mit80 1 52 88,274,528 IB D1Mit91 1 64 128,355,210 IB D1Mit30 1 70 135,259,675 IB D1Mit102 1 73 149,096,650 IB D1Mit110 1 88.1 169,688,648 IB D1Mit15 1 87.9 170,288,805 IB IB D1Mit115 1 99.7 179,610,205 IB IB D1Mit406 1 101.2 190,093,211 IB D1Mit292 1 107.3 193,227,344 IB D2Mit6 2 12.5 20,814,594 IB I D2Mit80 2 10 20,928,232 B IB D2Mit7 2 28 38,095,233 IB IB D2Mit9 2 37 65,277,459 IB D2Mit37 2 45 74,531,830 IB D2Mit66 2 47.8 84,657,700 IB D2Mit62 2 65 117,938,185 IB D2Mit17 2 69 122,639,898 IB D2Mit30 2 69 123,526,660 IB D2Mit57 2 82 148,128,121 IB IB D2Mit285 2 86 152,683,037 IB D2Mit51 2 95.5 162,976,178 IB D2Mit148 2 105 178,535,250 IB IB D3Mit62 3 4.6 17,467,423 IB D3Mit55 3 13.8 28,475,226 IB IB D3Mit22 3 33.7 69,522,098 B D3Mit51 3 35.2 73,304,714 IB D3Mit49 3 41 89,036,582
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