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Drugs Not Repackaged by Safecor Health

The following tables list specific medications that are not repackaged by Safecor Health due to regulatory restrictions or specific manufacturer requirements. The items not repackaged are alphabetically listed below, both by brand name (table 1) and generic name (table 2).

Please note: Safecor Health cannot repackage any beta lactam antibiotics (such as penicillins, amoxicillin and cephalosporins) or potent chemotherapeutic agents. Also, due to FDA restrictions, we cannot repackage half- or quarter-tabs, compounded or diluted drugs, powders, and ointments or creams.

Safecor Health can repackage most on the NIOSH list. Contact us for a complete list of hazardous drugs repackaged by Safecor Health.

Table 1. Do Not Repackage Drugs Sorted Alphabetically by Brand Name

Brand Name(s) Generic Name(s) Reason Item Cannot Be Repackaged

Adrucil Potent agent

Aspirin and Extended-Release Specific manufacturer recommendations for very Aggrenox Dipyridamole limited expiration dating

Albenza Albendazole Cost per dose prohibitive

Alkeran Potent chemotherapy agent

Augmentin Amoxicillin and Clavulanate Potassium Safecor Health does not repackage this drug class

Manufacturer states, "dispense in original container," Belsomra Suvorexant on the drug label Manufacturer states, "dispense in original container," Biktarvy Bictegravir, Emtricitabine and on the drug label

Bion Tears Dextran, Hypromellose Ophthalmic Drops Sterile and unpreserved

CeeNU Potent chemotherapy agent

Emtricitabine, Rilpivirine, Tenofovir Manufacturer states, "dispense in original container," Complera Disoproxil Fumarate on the drug label Manufacturer states, "dispense in original container," Crixivan Indinavir Sulfate on the drug label Culterelle GG Manufacturer states, "dispense in original container," Lactobacillus (cannot deblister; flag or overwrap service available) on the drug label

Cuprimine, Depen Penicillamine Penicillin derivative

Cytoxan Potent chemotherapy agent

Manufacturer states, "dispense in original container," Descovy Emtricitabine and Tenofovir Alafenamide Fumarate on the drug label Azilsartan Medoxomil and Manufacturer states, "dispense in original container," Edarbyclor Chlorthalidone on the drug label Chlorthalidone and Azilsartan Manufacturer states, "dispense in original container," Edarbyclor Medoxomil on the drug label Manufacturer states, "dispense in original container," Effient Prasugrel on the drug label

Emcyt Sodium Potent chemotherapy agent

Epculsa Sofosbuvir and Velpatasvir Cost per dose prohibitive

safecorhealth.com 800.447.1006 [email protected] Updated 4.17.19 | Page 1 Table 1 (continued). Do Not Repackage Drugs Sorted Alphabetically by Brand Name

Brand Name(s) Generic Name(s) Reason Item Cannot Be Repackaged

Gastrografin, MD-Gastroview Diatrizoate Meglumine and Diatrizoate Sodium Contrast agent/unpreserved/single-use bulk bottle

Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Manufacturer states, "dispense in original container," GENVOYA Alafenamide on the drug label

Gleevec Imatinib Potent chemotherapy agent

Harvoni Ledipasvir and Sofosbuvir Cost per dose prohibitive

Manufacturer states, "dispense in original container," Hepsera Dipivoxil on the drug label

Hydrea, Droxia Hydroxyurea Potent chemotherapy agent

Manufacturer states, "dispense in original container," Intelence Etravirine on the drug label Isentress Raltegravir Manufacturer states, "dispense in original container," (25 mg & 100 mg chewable tablets and liquid only) (25 mg & 100 mg chewable tablets and liquid only) on the drug label

Isovue Iopamidol Sterile and unpreserved

Manufacturer states, "dispense in original container," Kaletra liquid Lopinavir and Ritonavir on the drug label Specific manufacturer recommendations for very Kionex Sodium Polystyrene Sulfonate Suspension limited expiration dating

Leukeran Potent chemotherapy agent

Manufacturer states, "dispense in original container," Linzess Linaclotide on the drug label

Lysodren Potent chemotherapy agent

Mag 64, MagDelay, Slow-Mag, & GeriCare's Slow Magnesium Chloride Delayed-Release/Enteric-Coated Manufacturer states, "dispense in original container," Magnesium Chloride with Calcium Tablets on the drug label

Matulane Potent chemotherapy agent

Manufacturer states, "dispense in original container," Mestinon tablets Pyridostigmine tablets on the drug label Mineral Oil-Heavy Mineral Oil-Heavy For External Use Only (MFG: Medisca-NDC: 37877-0094-98 only) (MFG: Medisca-NDC: 37877-0094-98 only)

Mineral Oil-LIGHT Mineral Oil-LIGHT For External Use Only

Myleran Potent chemotherapy agent

Manufacturer states, "dispense in original container," Neoral Cyclosporine on the drug label Nitrostat Nitroglycerin SL Manufacturer states, "dispense in original container," (overwrap service available for unopened bottle) (overwrap service available for unopened bottle) on the drug label Norvir Ritonavir Manufacturer states, "dispense in original container," (capsules & liquid only; we can repackage tablets) (capsules & liquid only; we can repackage tablets) on the drug label Emtricitabine, Rilpivirine Hydrochloride, and Manufacturer states, "dispense in original container," ODEFSEY Tenofovir Alafenamide Fumarate on the drug label

Omnipaque Iohexol Sterile and unpreserved

Otovel (unit-dose ear drops) Sterile and unpreserved

Pancreaze Manufacturer states, "dispense in original container," Pancrelipase (can repackage Creon) on the drug label Pertzye Manufacturer states, "dispense in original container," Pancrelipase (can repackage Creon) on the drug label Manufacturer states, "dispense in original container," Pradaxa Etexilate Mesylate on the drug label Manufacturer states, "store in original package until Prevymis tablets Letermovir tablets use"

safecorhealth.com 800.447.1006 [email protected] | Page 2 Table 1 (continued). Do Not Repackage Drugs Sorted Alphabetically by Brand Name

Brand Name(s) Generic Name(s) Reason Item Cannot Be Repackaged

Purinethol Potent chemotherapy agent

Manufacturer states, "dispense in original container," Saphris sublingual tablet Asenapine sublingual tablet on the drug label

Sprycel Dasatinib Potent chemotherapy agent

Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Manufacturer states, "dispense in original container," Stribild Disoproxil Fumarate on the drug label

Syprine Trientine Cost per dose prohibitive

Tabloid Thioguanine Potent chemotherapy agent

Temodar Potent chemotherapy agent

Tivicay Dolutegravir Manufacturer states, "dispense in original container," (10 mg tablet only) (10 mg tablet only) on the drug label

Trexall, Rheumatrex Potent chemotherapy agent

Manufacturer states, "Do not repackage; dispense Treximet Sumatriptan and Naproxen Sodium tablets and store in original container" Manufacturer states, "dispense in original container," Triumeq Abacavir Sulfate, Dolutegravir Sodium, on the drug label Manufacturer states, "dispense in original container," Tybost Cobicistat on the drug label Viokace Manufacturer states, "dispense in original container," Pancrelipase (can repackage Creon) on the drug label Manufacturer states, "dispense in original container," Viracept Nelfinavir Mesylate on the drug label Manufacturer states, "dispense in original container," Xeljanz Tofacitinib Citrate on the drug label

Xeloda Potent chemotherapy agent

Zenpep Manufacturer states, "dispense in original container," Pancrelipase (can repackage Creon) on the drug label Manufacturer states, "dispense in original container," Zontivity Vorapaxar on the drug label

Table 2. Do Not Repackage Drugs Sorted Alphabetically by Generic Name

Generic Name(s) Brand Name(s) Reason Item Cannot Be Repackaged

Manufacturer states, "dispense in original container," Abacavir Sulfate, Dolutegravir Sodium, Lamivudine Triumeq on the drug label

Acetic Acid

Manufacturer states, "dispense in original container," Acetylcysteine Solution on the drug label; Sterile and unpreserved Manufacturer states, "dispense in original container," Adefovir Dipivoxil Hepsera on the drug label

Albendazole Albenza Cost per dose prohibitive

Albuterol Sulfate Inhalation Solution 0.5%: sterile Manufacturer states, "dispense in original container," multiple dose (NDC: 50383-741-20) on the drug label

Amoxicillin and Clavulanate Potassium Augmentin Safecor Health does not repackage this drug class

Manufacturer states, "dispense in original container," Asenapine sublingual tablet Saphris sublingual tablet on the drug label

safecorhealth.com 800.447.1006 [email protected] | Page 3 Table 2. Do Not Repackage Drugs Sorted Alphabetically by Generic Name

Generic Name(s) Brand Name(s) Reason Item Cannot Be Repackaged

Specific manufacturer recommendations for very Aspirin and Extended-Release Dipyridamole Aggrenox limited expiration dating Manufacturer states, "dispense in original container," Azilsartan Medoxomil and Chlorthalidone Edarbyclor on the drug label Manufacturer states, "dispense in original container," Bictegravir, Emtricitabine and Tenofovir Alafenamide Biktarvy on the drug label

Busulfan Myleran Potent chemotherapy agent

Manufacturer states, "dispense in original container," Caffeine Citrate Oral Solution on the drug label; Sterile and unpreserved

Capecitabine Xeloda Potent chemotherapy agent

CEPHALOSPORINS Safecor Health does not repackage this drug class (such as cephalexin and cefuroxime)

Chlorambucil Leukeran Potent chemotherapy agent

Manufacturer states, "dispense in original container," Chlorthalidone and Azilsartan Medoxomil Edarbyclor on the drug label Manufacturer states, "dispense in original container," Cobicistat Tybost on the drug label Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Manufacturer states, "dispense in original container," GENVOYA Alafenamide on the drug label Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Manufacturer states, "dispense in original container," Stribild Disoproxil Fumarate on the drug label

Cyclophosphamide Cytoxan Potent chemotherapy agent

Manufacturer states, "dispense in original container," Cyclosporine Neoral on the drug label Manufacturer states, "dispense in original container," Dabigatran Etexilate Mesylate Pradaxa on the drug label

Dasatinib Sprycel Potent chemotherapy agent

Dextran, Hypromellose Ophthalmic Drops Bion Tears Sterile and unpreserved

Diatrizoate Meglumine and Diatrizoate Sodium Gastrografin, MD-Gastroview Contrast agent/unpreserved/single-use bulk bottle

Dolutegravir Tivicay Manufacturer states, "dispense in original container," (10 mg tablet only) (10 mg tablet only) on the drug label Manufacturer states, "dispense in original container," Dolutegravir Sodium, Abacavir Sulfate, Lamivudine Triumeq on the drug label Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Manufacturer states, "dispense in original container," GENVOYA Alafenamide on the drug label Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Manufacturer states, "dispense in original container," Stribild Disoproxil Fumarate on the drug label Manufacturer states, "dispense in original container," Emtricitabine and Tenofovir Alafenamide Fumarate Descovy on the drug label Manufacturer states, "dispense in original container," Emtricitabine, Bictegravir and Tenofovir Alafenamide Biktarvy on the drug label Emtricitabine, Elvitegravir, Cobicistat, Tenofovir Manufacturer states, "dispense in original container," GENVOYA Alafenamide on the drug label Emtricitabine, Elvitegravir, Cobicistat, Tenofovir Manufacturer states, "dispense in original container," Stribild Disoproxil Fumarate on the drug label Emtricitabine, Rilpivirine Hydrochloride, and Manufacturer states, "dispense in original container," ODEFSEY Tenofovir Alafenamide Fumarate on the drug label Emtricitabine, Rilpivirine, Manufacturer states, "dispense in original container," Complera Fumarate on the drug label

Estramustine Phosphate Sodium Emcyt Potent chemotherapy agent

safecorhealth.com 800.447.1006 [email protected] | Page 4 Table 2 (continued). Do Not Repackage Drugs Sorted Alphabetically by Generic Name

Generic Name(s) Brand Name(s) Reason Item Cannot Be Repackaged

Manufacturer states, "dispense in original container," Etravirine Intelence on the drug label

Fluorouracil Adrucil Potent chemotherapy agent

Glycerin Liquid For Rectal or Topical Use

Hydroxyurea Hydrea, Droxia Potent chemotherapy agent

Imatinib Gleevec Potent chemotherapy agent

Manufacturer states, "dispense in original container," Indinavir Sulfate Crixivan on the drug label

Iohexol Omnipaque Sterile and unpreserved

Iopamidol Isovue Sterile and unpreserved

Culterelle GG (cannot deblister; we can flag or over- Manufacturer states, "dispense in original container," Lactobacillus wrap individual blisters) on the drug label Manufacturer states, "dispense in original container," Lamivudine, Abacavir Sulfate, Dolutegravir Sodium Triumeq on the drug label

Ledipasvir and Sofosbuvir Harvoni Cost per dose prohibitive

Manufacturer states, "store in original package until Letermovir tablets Prevymis tablets use" Letrozole Manufacturer states, "dispense in original container," (MFG: Dr. Reddy's-2.5 mg tablet only) on the drug label

Lidocaine 4% Topical Solution For External Use Only

Manufacturer states, "dispense in original container," Linaclotide Linzess on the drug label

Lomustine CeeNU Potent chemotherapy agent

Manufacturer states, "dispense in original container," Lopinavir and Ritonavir Kaletra liquid on the drug label Magnesium Chloride Delayed-Release/ Mag 64, MagDelay, Slow-Mag, & GeriCare's Slow Manufacturer states, "dispense in original container," Enteric-Coated Tablets Magnesium Chloride with Calcium on the drug label

Melphalan Alkeran Potent chemotherapy agent

Mercaptopurine Purinethol Potent chemotherapy agent

Methotrexate Trexall, Rheumatrex Potent chemotherapy agent

Mineral Oil-Heavy Mineral Oil-Heavy For External Use Only (MFG: Medisca-NDC: 37877-0094-98 only) (MFG: Medisca-NDC: 37877-0094-98 only)

Mineral Oil-LIGHT Mineral Oil-LIGHT For External Use Only

Mitotane Lysodren Potent chemotherapy agent

Manufacturer states, "dispense in original container," Nelfinavir Mesylate Viracept on the drug label Nitroglycerin SL Nitrostat Manufacturer states, "dispense in original container," (overwrap service available for unopened bottle) (overwrap service available for unopened bottle) on the drug label Pancrelipase Manufacturer states, "dispense in original container," Pancreaze, Pertzye, Viokace, Zenpep (can repackage Creon) on the drug label

Penicillamine Cuprimine, Depen Penicillin derivative

PENICILLINS Augmentin Safecor Health does not repackage this drug class (such as amoxicillin) Polyvitamin and Polyvitamin with iron liquid Incompatible with Safecor Health syringe (MFG: Rugby only) Manufacturer states, "dispense in original container," Prasugrel Effient on the drug label

safecorhealth.com 800.447.1006 [email protected] | Page 5 Table 2 (continued). Do Not Repackage Drugs Sorted Alphabetically by Generic Name

Generic Name(s) Brand Name(s) Reason Item Cannot Be Repackaged

Procarbazine Matulane Potent chemotherapy agent

Manufacturer states, "dispense in original container," Pyridostigmine tablets Mestinon tablets on the drug label Raltegravir Isentress Manufacturer states, "dispense in original container," (25 mg & 100 mg chewable tablets and liquid only) (25 mg & 100 mg chewable tablets and liquid only) on the drug label Rilpivirine Hydrochloride, Emtricitabine, and Manufacturer states, "dispense in original container," ODEFSEY Tenofovir Alafenamide Fumarate on the drug label Rilpivirine, Emtricitabine, Tenofovir Disoproxil Manufacturer states, "dispense in original container," Complera Fumarate on the drug label Ritonavir Norvir Manufacturer states, "dispense in original container," (capsules & liquid only; we can repackage tablets) (capsules & liquid only; we can repackage tablets) on the drug label Manufacturer states, "dispense in original container," Ritonavir and Lopinavir Kaletra liquid on the drug label Senna syrup Incompatible in Safecor Health cups (MFG: GeriCare only) Specific manufacturer recommendations for very Sodium Polystyrene Sulfonate Suspension Kionex limited expiration dating

Sofosbuvir and Ledipasvir Harvoni Cost per dose prohibitive

Sofosbuvir and Velpatasvir Epculsa Cost per dose prohibitive

Manufacturer states, "Do not repackage; dispense Sumatriptan and Naproxen Sodium tablets Treximet and store in original container" Manufacturer states, "dispense in original container," Suvorexant Belsomra on the drug label

Temozolomide Temodar Potent chemotherapy agent

Manufacturer states, "dispense in original container," Tenofovir Alafenamide Fumarate and Emtricitabine Descovy on the drug label Tenofovir Alafenamide Fumarate, Emtricitabine, and Manufacturer states, "dispense in original container," ODEFSEY Rilpivirine Hydrochloride on the drug label Manufacturer states, "dispense in original container," Tenofovir Alafenamide, Bictegravir and Emtricitabine Biktarvy on the drug label Tenofovir Alafenamide, Elvitegravir, Cobicistat, Manufacturer states, "dispense in original container," GENVOYA Emtricitabine on the drug label Tenofovir Disoproxil Fumarate, Elvitegravir, Manufacturer states, "dispense in original container," Stribild Cobicistat, Emtricitabine on the drug label Tenofovir Disoproxil Fumarate, Emtricitabine, Manufacturer states, "dispense in original container," Complera Rilpivirine on the drug label

Thioguanine Tabloid Potent chemotherapy agent

Manufacturer states, "dispense in original container," Tofacitinib Citrate Xeljanz on the drug label

Trientine Syprine Cost per dose prohibitive

Velpatasvir and Sofosbuvir Epculsa Cost per dose prohibitive

Manufacturer states, "dispense in original container," Vorapaxar Zontivity on the drug label

Contact us today for additional information on Safecor Health’s repackaging capabilities.

safecorhealth.com 800.447.1006 [email protected] | Page 6