Hinge Region in DNA Packaging Terminase Pul15 of Herpes Simplex Virus: a Potential Allosteric Target for Antiviral Drugs
Louisiana State University LSU Digital Commons Faculty Publications School of Renewable Natural Resources 10-1-2019 Hinge Region in DNA Packaging Terminase pUL15 of Herpes Simplex Virus: A Potential Allosteric Target for Antiviral Drugs Lana F. Thaljeh Louisiana State Univ, Dept Biol Sci, lthalj1@lsu.edu J. Ainsley Rothschild Louisiana State Univ, Div Elect & Comp Engn, jroths2@lsu.edu Misagh Naderi Louisiana State Univ, Dept Biol Sci, misagh.naderi@gmail.com Lyndon M. Coghill Louisiana State Univ, Dept Biol Sci, lcoghill@lsu.edu Follow this and additional works at: https://digitalcommons.lsu.edu/agrnr_pubs Part of the Biology Commons Recommended Citation Thaljeh, Lana F.; Rothschild, J. Ainsley; Naderi, Misagh; and Coghill, Lyndon M., "Hinge Region in DNA Packaging Terminase pUL15 of Herpes Simplex Virus: A Potential Allosteric Target for Antiviral Drugs" (2019). Faculty Publications. 4. https://digitalcommons.lsu.edu/agrnr_pubs/4 This Article is brought to you for free and open access by the School of Renewable Natural Resources at LSU Digital Commons. It has been accepted for inclusion in Faculty Publications by an authorized administrator of LSU Digital Commons. For more information, please contact gcoste1@lsu.edu. biomolecules Article Hinge Region in DNA Packaging Terminase pUL15 of Herpes Simplex Virus: A Potential Allosteric Target for Antiviral Drugs Lana F. Thaljeh 1, J. Ainsley Rothschild 1, Misagh Naderi 1, Lyndon M. Coghill 1,2 , Jeremy M. Brown 1 and Michal Brylinski 1,2,* 1 Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA; lthalj1@lsu.edu (L.F.T.); jroths2@lsu.edu (J.A.R.); mnader5@lsu.edu (M.N.); lcoghill@lsu.edu (L.M.C.); jembrown@lsu.edu (J.M.B.) 2 Center for Computation & Technology, Louisiana State University, Baton Rouge, LA 70803, USA * Correspondence: michal@brylinski.org; Tel.: +225-578-2791; Fax: +225-578-2597 Received: 10 September 2019; Accepted: 8 October 2019; Published: 12 October 2019 Abstract: Approximately 80% of adults are infected with a member of the herpesviridae family.
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